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Identifying purgative targets of sennoside A via in situ biotransformation of prodrug-based probes
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作者 Zhen Liu Xinyue Geng +6 位作者 Xinyue Liu Mengru Li Xiang Li Zhixin Zhang Gan Luo Ying Wang Xiaoyan Gao 《Journal of Pharmaceutical Analysis》 2025年第4期873-875,共3页
Prodrugs need to be converted to active drugs to exert their pharmacological activities.Identifying the direct targets of active drugs is essential to elucidate the pharmacological mechanisms of prodrugs,but remains c... Prodrugs need to be converted to active drugs to exert their pharmacological activities.Identifying the direct targets of active drugs is essential to elucidate the pharmacological mechanisms of prodrugs,but remains challenging,especially for active drugs with low stability. 展开更多
关键词 purgative targets active drugs pharmacological activities exert their pharmacological activitiesidentifying direct targets active drugs prodrug based probes situ biotransformation direct targets elucidate pharmacological mechanisms
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