A new,selective Ru(Ⅱ)-catalyzed alkynylation reaction of isoquinolones,quinazolones and phthalazinones with readily available bromoalkynes has been developed.This reaction enables the selective construction of a new ...A new,selective Ru(Ⅱ)-catalyzed alkynylation reaction of isoquinolones,quinazolones and phthalazinones with readily available bromoalkynes has been developed.This reaction enables the selective construction of a new C(sp^(2))-C(sp)bond through C-H activation and C-Br functionalization,and offers an effective and selective route to synthesizing highly valuable alkynylated isoquinolone,quinazolone and phthalazinonederivatives with a wide substrate scope and highselectivity.展开更多
I.INTRODUCTION In this decade, much attention has been focused on the research into polynucle- otide analogs, especially their biological activity properties and more reports have been seen. But reports on the synthes...I.INTRODUCTION In this decade, much attention has been focused on the research into polynucle- otide analogs, especially their biological activity properties and more reports have been seen. But reports on the synthesis of polyurethane are still rare. Hiraoka and Yakoyama reported the synthesis of polyurethanes containing nucleic acid bases展开更多
基金supported by the Natural Science Foundation of Shandong Province(ZR2019BB011)the Scientific Research Foundation of Qingdao University of Science&Technology(010029022).
文摘A new,selective Ru(Ⅱ)-catalyzed alkynylation reaction of isoquinolones,quinazolones and phthalazinones with readily available bromoalkynes has been developed.This reaction enables the selective construction of a new C(sp^(2))-C(sp)bond through C-H activation and C-Br functionalization,and offers an effective and selective route to synthesizing highly valuable alkynylated isoquinolone,quinazolone and phthalazinonederivatives with a wide substrate scope and highselectivity.
基金Project supported by the Committee of National Education
文摘I.INTRODUCTION In this decade, much attention has been focused on the research into polynucle- otide analogs, especially their biological activity properties and more reports have been seen. But reports on the synthesis of polyurethane are still rare. Hiraoka and Yakoyama reported the synthesis of polyurethanes containing nucleic acid bases
