AIM： To compare the visual functional outcomes with accommodating and multifocal intraocular lenses（IOLs）.METHODS： Our retrospective comparative study included 51 patients（60 eyes） received implantation of an ac...AIM： To compare the visual functional outcomes with accommodating and multifocal intraocular lenses（IOLs）.METHODS： Our retrospective comparative study included 51 patients（60 eyes） received implantation of an accommodating IOL（Tetraflex;16 patients,20 eyes）,a refractive multifocal IOL（Re Zoom;18 patients,20 eyes）,or a diffractive multifocal IOL（ZMA00;17 patients,20 eyes）.Subjective refraction,visual acuity,contrast sensitivity（CS）,intraocular aberration,and subjective photic phenomena were detected at 3mo after surgery.RESULTS： The spherical equivalent in the three groups was-0.38±0.54 D,0.14±0.56 D,and 0.35±0.41 D,respectively.No statistically significant differences were found in uncorrected and corrected distance visual acuity and uncorrected intermediate visual acuity among the groups（P=0.39）.The Re Zoom group had significantly better distance-corrected intermediate visual acuity than the ZMA00 group（P=0.003）.The ZMA00 group had significantly better near visual acuity than the other groups（P〈0.05）.Better contrast sensitivity values were observed in the Tetraflex group under most of the spatial frequencies conditions（P=0.025）.The total aberration was lowest in the ZMA00 group（P=0.000）,and the spherical aberration was highest in the Tetraflex group（P=0.000）.The three groups had similar frequency of ghosting and glare,and the Tetraflex group had a low rate of halos（P=0.01）.CONCLUSION： Both accommodating and multifocal IOLs can successfully restore distance and uncorrected intermediate visual acuities.Tetraflex accommodating IOLs perform better in CS and with less halos of photic phenomena.Re Zoom refractive multifocal IOLs havebetter performance in distance-corrected intermediate visual acuity than ZMA00 diffractive multifocal IOLs,and the latter achieved better near visual acuity and efficiently decreased the optical aberration.展开更多
The present review describes recent advances in application of accommodating intraocular lenses （AIOLs）. Standard monofocal intraocular lenses （MIOLs） only correct distance vision, while AIOLs are designed to allo...The present review describes recent advances in application of accommodating intraocular lenses （AIOLs）. Standard monofocal intraocular lenses （MIOLs） only correct distance vision, while AIOLs are designed to allow both good distance vision and near vision, which is achieved through the contraction and relaxation of ciliary muscles by providing transformation of the axial movement or curvature of the lens. Thus, AIOLs may be a better choice for those patients who demand a higher level of visual performance. Since techniques to analyze the performance of AIOLs have not been standardized, and there is a variety of both subjective and objective methods, it is hard to measure the performance of these intraocular lenses. By evaluating advantages and disadvantages of various AIOLs, and introducing techniques for measurement the performance postoperative, this paper can provide some relative information on choosing the type of AIOLs in the clinic.展开更多
MARIA Jacobs and her husband left their home in South Africa and moved to Guangzhou, the capital city of south China＇s Guangdong Province. two years ago She enjoys her life in the city, mainly because she lives in th...MARIA Jacobs and her husband left their home in South Africa and moved to Guangzhou, the capital city of south China＇s Guangdong Province. two years ago She enjoys her life in the city, mainly because she lives in the Ascott high-end serviced apartment complex located in the city＇s downtown area. which is not only close to all kinds of entertainment, but also offers convenient access to major business and shopping districts nearby.展开更多
AIM: To compare the results of in vivo human high resolution image registration studies of the eye during accommodation to the predictions of mathematical and finite element models of accommodation. METHODS: Data from...AIM: To compare the results of in vivo human high resolution image registration studies of the eye during accommodation to the predictions of mathematical and finite element models of accommodation. METHODS: Data from published high quality image registration studies of pilocarpine induced accommodative changes of equatorial lens radius(ELR) and central lens thickness(CLT) were statistically analyzed. RESULTS: The mean changes in ELR and CLT were 6.76 μm/diopter and 6.51 μm/diopter, respectively. The linear regressions, reflecting the association between ELR and accommodative amplitude(AAELR) was: slope=6.58 μm/diopter, r^2=0.98, P<0.0001 and between CLT and AACLT was: slope=6.75 μm/diopter, r^2=0.83, P<0.001. On the basis of these relationships, the CLT slope and the AAELR were used to predict the measured change in ELR(ELRpredicted). There was no statistical difference between ELRpredicted and the measured ELR as demonstrated by a Student's paired t-test: P=0.96 and linear regression analysis: slope=0.97, r^2=0.98, P<0.00001.CONCLUSION: Image registration with invariant positional references demonstrates that ELR and CLT equivalently minimally increase ~7.0 μm/diopter during accommodation. The small equivalent increases in ELRand CLT are associated with a large accommodative amplitude. These findings are consistent with the predictions of mathematical and finite element models that specified the stiffness of the lens nucleus is the same or greater than the lens cortex and that accommodation involves a small force(<5 g).展开更多
AIM:To evaluate the efficacy of the total computer vision syndrome questionnaire(CVS-Q)score as a predictive tool for identifying individuals with symptomatic binocular vision anomalies and refractive errors.METHODS:A...AIM:To evaluate the efficacy of the total computer vision syndrome questionnaire(CVS-Q)score as a predictive tool for identifying individuals with symptomatic binocular vision anomalies and refractive errors.METHODS:A total of 141 healthy computer users underwent comprehensive clinical visual function assessments,including evaluations of refractive errors,accommodation(amplitude of accommodation,positive relative accommodation,negative relative accommodation,accommodative accuracy,and accommodative facility),and vergence(phoria,positive and negative fusional vergence,near point of convergence,and vergence facility).Total CVS-Q scores were recorded to explore potential associations between symptom scores and the aforementioned clinical visual function parameters.RESULTS:The cohort included 54 males(38.3%)with a mean age of 23.9±0.58y and 87 age-matched females(61.7%)with a mean age of 23.9±0.53y.The multiple regression model was statistically significant[R²=0.60,F=13.28,degrees of freedom(DF=17122,P<0.001].This indicates that 60%of the variance in total CVS-Q scores(reflecting reported symptoms)could be explained by four clinical measurements:amplitude of accommodation,positive relative accommodation,exophoria at distance and near,and positive fusional vergence at near.CONCLUSION:The total CVS-Q score is a valid and reliable tool for predicting the presence of various nonstrabismic binocular vision anomalies and refractive errors in symptomatic computer users.展开更多
Psychoeducation is a structured but straightforward and effective treatment,which consists of educating patients and family members about psychiatric disorders,teaching them to cope with the illness,and supporting the...Psychoeducation is a structured but straightforward and effective treatment,which consists of educating patients and family members about psychiatric disorders,teaching them to cope with the illness,and supporting them during treatment.Psychoeducation as an independent treatment is effective in schizophrenia and bipolar disorder.Psychoeducation is a core component of cognitivebehavioural therapy(CBT)or exposure and response prevention(ERP)treatment,which are the standard psychotherapeutic treatments for obsessive-compulsive disorder(OCD).However,research on the benefits of psychoeducational treatments in OCD is limited compared to schizophrenia and bipolar disorders.Very few studies have examined psychoeducation as an independent treatment for OCD,and its efficacy is not proven.The effectiveness of CBT or ERP for OCD is well established,but the contribution of psychoeducation to the efficacy of these treatments is unclear.Recently,there has been a greater understanding of maladaptive family responses,such as accommodation and antagonism,that worsen the outcome and treatment response in OCD.Family-based psychoeducational treatments targeting inappropriate family responses are effective in reducing obsessional symptoms,attenuating the negative family impact of OCD,and improving patient and family functioning.Family-based psychoeducation is a promising treatment for OCD,but there are methodological issues with the evidence,and trials among adult patients are limited compared to children and adolescents.The other obstacles to the implementation of psychoeducational treatments of OCD are the large treatment gap,lack of research from low-and middle-income countries,and the limited attempts to develop culturally adapted treatments in these countries.Thus,further research should focus on optimising psychoeducational treatments for OCD and efficiently delivering these treatments in routine clinical settings.展开更多
Crystallographic texture engineering is a key strategy for enhancing the mechanical properties of polycrystalline magnesium(Mg)alloys.Due to the intrinsic anisotropy of the hexagonal close-packed(HCP)structure,the def...Crystallographic texture engineering is a key strategy for enhancing the mechanical properties of polycrystalline magnesium(Mg)alloys.Due to the intrinsic anisotropy of the hexagonal close-packed(HCP)structure,the deformation behavior of Mg alloys is significantly governed by individual grain deformation and multi-grain interactions,both dictated by crystallographic texture.In the current study,enhanced ductility was achieved in a Mg-Al-Zn-Mn dilute alloy by tailoring a strong basal texture into a transverse-direction-spread elliptical texture through the minor addition of yttrium(Y).Systematic quasi-in-situ electron backscatter diffraction(EBSD)and dislocation/disclination density analyses were performed to examine the microstructural evolution during deformation.We found that disclinations emerge from defect reactions,including dislocation-grain boundary(GB)and twin-GB interactions,which facilitate twinning plasticity and intergranular accommodation in the elliptical-textured alloy,resulting in improved work-hardening capacity and higher ductility(28.5% along the rolling direction and 32.2%along the transverse direction).By introducing disclination analysis to elucidate defect reactions,multi-grain interactions and the associated microstructure-property relationships in polycrystalline metals,our work provides new insights into the design of advanced Mg alloys with enhanced ductility and formability through crystallographic texture engineering.展开更多
ISO releases two standards for tourism ISO 9468:2025,Tourism and related services-Online travel agency(OTA)-Guidelines for online accommodation booking platform services,and ISO 25639-1:2025,Exhibitions and events-Par...ISO releases two standards for tourism ISO 9468:2025,Tourism and related services-Online travel agency(OTA)-Guidelines for online accommodation booking platform services,and ISO 25639-1:2025,Exhibitions and events-Part 1:Vocabulary,were released recently,the development of which were led by China.展开更多
AIM:To evaluate the effects of refractive errors and binocular vision anomalies on the quality of life(QOL)of university students.METHODS:This cross-sectional analytical study was conducted on university students usin...AIM:To evaluate the effects of refractive errors and binocular vision anomalies on the quality of life(QOL)of university students.METHODS:This cross-sectional analytical study was conducted on university students using simple random sampling.Objective refraction,ocular alignment,vergence and accommodative performance were measured and assessed in all participants.Data on QOL were collected using the College of Optometrists in Vision Development-Quality of Life(COVD-QOL)Questionnaire.The effect of mentioned parameters on the QOL were evaluated.RESULTS:Totally 726 students with mean age of 21.35±1.88y were evaluated in this study,51.5%of whom were female.Esophoria was caused significantly lower QOL in the domains of somatic symptoms and occupationalphysical symptoms(P<0.05);Besides,esotropia decreased QOL in domains of somatic symptoms P=0.002 and psychological factors(P=0.023).Students with accommodation insufficiency experienced more symptoms in all domains(P<0.05)except for psychological factors(P=0.07).Increasing in the near point of convergence and accommodation and decreases QOL and increasing accommodative facility increases QOL(all P<0.05).Myopia and astigmatism cause decrease in QOL(both P<0.05),but hyperopic students had better QOL in comparison with others(P<0.05).CONCLUSION:Screening programs and treatment of refractive errors and binocular vision anomalies,especially phoria and accommodative insufficiency,positively impact the QOL and academic achievements of university students.展开更多
The selection of twin variants plays a critical role in shaping the deformation texture and mechanical properties of magnesium alloys that are limited by slip systems and diverse twinning modes.In this study,we invest...The selection of twin variants plays a critical role in shaping the deformation texture and mechanical properties of magnesium alloys that are limited by slip systems and diverse twinning modes.In this study,we investigated the twin variant selection and the effect of twinning activity on the strain hardening of a hot-rolled AZ31 magnesium alloy by quasi-in-situ EBSD.Moreover,the Schmid factors and the displacement gradient tensors were computed to evaluate the activation of twin variants.The results reveal that the yield strength increased progressively after each deformation step,driven by grain subdivision and texture hardening induced by extension{1012}twinning and the Basinski effect at large strains.The nucleation and growth of the{1012}twins occurred either sequentially or simultaneously during the plastic deformation.At low plastic strains,the activation of most twin variants followed the high Schmid factor criterion while the other twin variants with lower Schmid factors were activated due to the interactions with preexisting twins characterized by high misorientation angles(around 60°).Additionally,this non-Schmid factor scenario was also attributed to low coordinated strain requirements from neighboring grains,showing the critical role of local deformation accommodation in the twinning process.These findings advance the fundamental understanding of the twin variant selection and its implications for the microstructure-property relationship in magnesium alloys for structural applications.展开更多
AIM:To explore choroidal thickness(CT)and choroidal vascularity index(CVI)changes around the macula and optic nerve head(ONH)using swept-source optical coherence tomography(SS-OCT)after small-incision lenticule extrac...AIM:To explore choroidal thickness(CT)and choroidal vascularity index(CVI)changes around the macula and optic nerve head(ONH)using swept-source optical coherence tomography(SS-OCT)after small-incision lenticule extraction(SMILE)and evaluate their associations with accommodation and aberrations.METHODS:Participants were divided into more myopic group(43 eyes)and less myopic group(33 eyes)according to refractive error.SS-OCT,negative relative accommodation(NRA),and positive relative accommodation(PRA)were analyzed before and 1d,1wk,and 1mo postoperatively.Root mean square higher-order aberrations(RMS HOAs),spherical aberrations(SAs),and coma were compared preoperative,1wk,and 1mo postoperatively.RESULTS:After surgery,RMS(0.29±0.26)and Coma(0.16±0.19)all increased.In the more myopic group,central and T macular CT(247.58±63.81 a n d 276.45±62.52μm)increased.NRA(0.41±0.51)and PRA(0.10±1.30)decreased,and SAs(0.21±0.21)increased.In the less myopic group,all regional and mean macular CT increased.NRA was correlated with mean and inferior CTs and mean ONH CVI.SE was correlated with macular CT,CVI,and ONH CT.Mean macular and ONH CTs were associated with RMS HOA,SA,and coma.Macular T2 CT was a significant predictor of SA.Macular T2 and N1 CT were correlated with coma.CONCLUSION:More variations in accommodation and aberrations and fewer choroid thickens on macular and ONH are found in more myopic eyes after SMILE.Choroidal values are associated with accommodation and aberrations during SMILE.Choroid parameters on SS-OCT varies in eyes with different refractive errors after SMILE and has an association with accommodation and visual quality.展开更多
Two international standards on tourism,ISO 9468:2025,Tourism and related services-Online travel agency(OTA)-Guidelines for online accommodation booking platform services,and ISO 25639-1:2025,Exhibitions and events-Par...Two international standards on tourism,ISO 9468:2025,Tourism and related services-Online travel agency(OTA)-Guidelines for online accommodation booking platform services,and ISO 25639-1:2025,Exhibitions and events-Part 1:Vocabulary,were recently released by ISO,the development of which was led by China.展开更多
Against the backdrop of active global responses to climate change and the accelerated green and low-carbon energy transition,the co-optimization and innovative mechanism design of multimodal energy systems have become...Against the backdrop of active global responses to climate change and the accelerated green and low-carbon energy transition,the co-optimization and innovative mechanism design of multimodal energy systems have become a significant instrument for propelling the energy revolution and ensuring energy security.Under increasingly stringent carbon emission constraints,how to achieve multi-dimensional improvements in energy utilization efficiency,renewable energy accommodation levels,and system economics-through the intelligent coupling of diverse energy carriers such as electricity,heat,natural gas,and hydrogen,and the effective application of market-based instruments like carbon trading and demand response-constitutes a critical scientific and engineering challenge demanding urgent solutions.展开更多
The asymmetric or periodically varying blade loads resulted by wind shear become more significant as the blade length is increased to capture more wind power.Additionally,compared with the onshore wind turbines,their ...The asymmetric or periodically varying blade loads resulted by wind shear become more significant as the blade length is increased to capture more wind power.Additionally,compared with the onshore wind turbines,their offshore counterparts are subjected to additional wave loadings in addition to wind loadings within their lifetime.Therefore,vibration control and fatigue load mitigation are crucial for safe operation of large-scale offshore wind turbines.In view of this,a multi-body model of an offshore bottom-fixed wind turbine including a detailed drivetrain is established in this paper.Then,an individual pitch controller(IPC)is designed using disturbance accommodating control.State feedback is used to add damping in flexible modes of concern,and a state estimator is designed to predict unmeasured signals.Continued,a coupled aero-hydro-servo-elastic model is constructed.Based on this coupled model,the load reduction effect of IPC and the dynamic responses of the drivetrain are investigated.The results showed that the designed IPC can effectively reduce the structural loads of the wind turbine while stabilizing the turbine power out-put.Moreover,it is found that the drivetrain dynamic responses are improved under IPC.展开更多
My Fair Lady is a movie about how a lower class flower girl turns to an upper class lady by simply changing her language at the help of a linguist.It demonstrates the importance of communication accommodation,especial...My Fair Lady is a movie about how a lower class flower girl turns to an upper class lady by simply changing her language at the help of a linguist.It demonstrates the importance of communication accommodation,especially convergent accommodation,in using language as code and behavior to construct identity in the target community.展开更多
Patients with liver cirrhosis exhibit several features of gut dysfunction which may contribute to the development of cirrhosis complications as well as have an impact on nutritional status and health-related quality o...Patients with liver cirrhosis exhibit several features of gut dysfunction which may contribute to the development of cirrhosis complications as well as have an impact on nutritional status and health-related quality of life.Gastrointestinal symptoms are common in cirrhosis and their pathophysiology probably involves factors related to liver disease severity,psychological distress,and gut dysfunction(e.g.,increased gastric sensitivity to distension and delayed gut transit).They may lead to reduced food intake and,thus,may contribute to the nutritional status deterioration in cirrhotic patients.Although tense ascites appears to have a negative impact on meal-induced accommodation of the stomach,published data on gastric accommodation in cirrhotics without significant ascites are not unanimous.Gastric emptying and small bowel transit have generally been shown to be prolonged.This may be related to disturbances in postprandial glucose,insulin,and ghrelin levels,which,in turn,appear to be associated to insulin resistance,a common finding in cirrhosis.Furthermore,small bowel manometry disturbances and delayed gut transit may be associated with the development of small bowel bacterial overgrowth.Finally,several studies have reported intestinal barrier dysfunction in patients with cirrhosis(especially those with portal hypertension),which is related to bacterial translocation and permeation of intestinal bacterial products,e.g.,endo-toxin and bacterial DNA,thus potentially being involved in the pathogenesis of complications of liver cirrhosis.展开更多
AIM： To study effects of orthokeratology（Ortho-k） on accommodation function in myopic children. METHODS： A prospective, non-randomized, case-control study was performed from September to October 2016. Eighty-three...AIM： To study effects of orthokeratology（Ortho-k） on accommodation function in myopic children. METHODS： A prospective, non-randomized, case-control study was performed from September to October 2016. Eighty-three children with myopia were divided into two groups. One group was treated with the rigid contact lens for overnight Ortho-k, and the other was treated with single-vision spectacle lens（SVL）. Accommodation function were assessed by accommodative amplitude（AA）, accommodative sensitivity（AS）, accommodative lag（Lag）, negative relative accommodation（NRA）, and positive relative accommodation（PRA） before and 1, 3, 6 and 12 mo after treated. RESULTS： Totally 72 myopic children were finished the follow-up： 37 in Ortho-k group and 35 in SVL group. Wearing time had a significant effect on AA, AS, Lag, and NRA of myopic children in two groups（all P〈0.05）. Meanwhile, there was an interaction effect between wearing time and wearing types（FAA=5.3, FAS=45.5, FLag=7.0, FNRA=3.7, all P〈0.05）. However, the between-group difference of AA（F=0.1）, AS（F=3.2）, Lag（F=1.1）, NRA（F=0.3）, and PRA（F=0.1） showed no significance. AA, AS, NRA, Lag and PRA were improved significantly in Ortho-k group within 1 to 6 mo after wearing. CONCLUSION： Wearing Ortho-k can improve the accommodation function of myopic children, which might be one of the mechanisms for myopia control.展开更多
Gastric accommodation is important for the understanding of the pathophysiology in functional dyspepsia and is also relevant for symptom generation in other disorders. The term gastric accommodation has at least three...Gastric accommodation is important for the understanding of the pathophysiology in functional dyspepsia and is also relevant for symptom generation in other disorders. The term gastric accommodation has at least three different meanings： The accommodation process, the accommodation reflex, and the accommodation response. The gastric accommodation process is a complex phenomenon that describes how the size of the gastric compartment changes in response to a meal. The electronic barostat is considered the gold standard in assessing gastric accommodation. Imaging methods, including MRI, SPECT, and ultrasonography may also be used, particularly in patients who are stress-responsive, e.g. functional dyspepsia patients, as a non-invasive and less stress-inducing method is favourable. Ultrasonography satisfies these criteria as it does not by itself distort the physiological response in stress-responsive individuals.展开更多
AIM: To assess the value of ultrasonography (US) in evaluation of proximal gastric accommodation disorder in patients with functional dyspepsia (FD). METHODS: Between April 2011 and March 2012, 45 patients with FD and...AIM: To assess the value of ultrasonography (US) in evaluation of proximal gastric accommodation disorder in patients with functional dyspepsia (FD). METHODS: Between April 2011 and March 2012, 45 patients with FD and 27 healthy volunteers were enrolled in this study. Two-dimensional ultrasound (2DUS) and 3-dimensional ultrasound (3DUS) were performed sequentially to measure proximal gastric area (PGA), maximal proximal gastric diameter (MPGD), and proximal gastric volume (PGV). These values were measured separately in the two groups every other 5 min for a duration of 25 min after the beginning of ingestion of a test meal. Air pocket grading was done separately for images of 2DUS and blocks of 3DUS obtained at five scanning time points. RESULTS: Both PGA and PGV of patients were significantly smaller than healthy controls (P = 0.000 and 0.002, respectively). Comparing the two parameters between the groups at each time point, the differences were also statistically significant (P = 0.000-0.013), except at 10 min for the PGV (P = 0.077). However, no overall difference was found between the groups in the MPGD measurements (P = 0.114), though it was statistically significant at a 20-minute examination point (P = 0.026). A total of 360 sets or blocks of images were obtained for both 2DUS and 3DUS. For the images analyzed by 2DUS, none were excluded because of gastric gas, and 50 (13.9%) and 310 (86.1%) sets were determined as air pockets grades 1 and 2, respectively. For the images analyzed by 3DUS, 23 (6.4%) blocks were excluded from the measurement due to presence of a large fundus air pocket (grade 3); fifty (13.9%) and 287 (79.7%) blocks were also graded as 1 and 2, respectively. CONCLUSION: Measurement of both PGA and PGV by 2DUS and 3DUS could be useful for assessment of the proximal gastric accommodation.展开更多
基金Supported by the National Natural Science Foundation of China(No.81600721)the Key Laboratory Program of Shandong Eye Institute(NO.2014-1)+2 种基金Medicine Science and Technology Development Program of Shandong Province(No.2015WS0204)the Science and Technology plan of Qingdao,China(No.15-9-1-35-jch)the Innovation Project of Shandong Academy of Medical Sciences
文摘AIM： To compare the visual functional outcomes with accommodating and multifocal intraocular lenses（IOLs）.METHODS： Our retrospective comparative study included 51 patients（60 eyes） received implantation of an accommodating IOL（Tetraflex;16 patients,20 eyes）,a refractive multifocal IOL（Re Zoom;18 patients,20 eyes）,or a diffractive multifocal IOL（ZMA00;17 patients,20 eyes）.Subjective refraction,visual acuity,contrast sensitivity（CS）,intraocular aberration,and subjective photic phenomena were detected at 3mo after surgery.RESULTS： The spherical equivalent in the three groups was-0.38±0.54 D,0.14±0.56 D,and 0.35±0.41 D,respectively.No statistically significant differences were found in uncorrected and corrected distance visual acuity and uncorrected intermediate visual acuity among the groups（P=0.39）.The Re Zoom group had significantly better distance-corrected intermediate visual acuity than the ZMA00 group（P=0.003）.The ZMA00 group had significantly better near visual acuity than the other groups（P〈0.05）.Better contrast sensitivity values were observed in the Tetraflex group under most of the spatial frequencies conditions（P=0.025）.The total aberration was lowest in the ZMA00 group（P=0.000）,and the spherical aberration was highest in the Tetraflex group（P=0.000）.The three groups had similar frequency of ghosting and glare,and the Tetraflex group had a low rate of halos（P=0.01）.CONCLUSION： Both accommodating and multifocal IOLs can successfully restore distance and uncorrected intermediate visual acuities.Tetraflex accommodating IOLs perform better in CS and with less halos of photic phenomena.Re Zoom refractive multifocal IOLs havebetter performance in distance-corrected intermediate visual acuity than ZMA00 diffractive multifocal IOLs,and the latter achieved better near visual acuity and efficiently decreased the optical aberration.
文摘The present review describes recent advances in application of accommodating intraocular lenses （AIOLs）. Standard monofocal intraocular lenses （MIOLs） only correct distance vision, while AIOLs are designed to allow both good distance vision and near vision, which is achieved through the contraction and relaxation of ciliary muscles by providing transformation of the axial movement or curvature of the lens. Thus, AIOLs may be a better choice for those patients who demand a higher level of visual performance. Since techniques to analyze the performance of AIOLs have not been standardized, and there is a variety of both subjective and objective methods, it is hard to measure the performance of these intraocular lenses. By evaluating advantages and disadvantages of various AIOLs, and introducing techniques for measurement the performance postoperative, this paper can provide some relative information on choosing the type of AIOLs in the clinic.
文摘MARIA Jacobs and her husband left their home in South Africa and moved to Guangzhou, the capital city of south China＇s Guangdong Province. two years ago She enjoys her life in the city, mainly because she lives in the Ascott high-end serviced apartment complex located in the city＇s downtown area. which is not only close to all kinds of entertainment, but also offers convenient access to major business and shopping districts nearby.
文摘AIM: To compare the results of in vivo human high resolution image registration studies of the eye during accommodation to the predictions of mathematical and finite element models of accommodation. METHODS: Data from published high quality image registration studies of pilocarpine induced accommodative changes of equatorial lens radius(ELR) and central lens thickness(CLT) were statistically analyzed. RESULTS: The mean changes in ELR and CLT were 6.76 μm/diopter and 6.51 μm/diopter, respectively. The linear regressions, reflecting the association between ELR and accommodative amplitude(AAELR) was: slope=6.58 μm/diopter, r^2=0.98, P<0.0001 and between CLT and AACLT was: slope=6.75 μm/diopter, r^2=0.83, P<0.001. On the basis of these relationships, the CLT slope and the AAELR were used to predict the measured change in ELR(ELRpredicted). There was no statistical difference between ELRpredicted and the measured ELR as demonstrated by a Student's paired t-test: P=0.96 and linear regression analysis: slope=0.97, r^2=0.98, P<0.00001.CONCLUSION: Image registration with invariant positional references demonstrates that ELR and CLT equivalently minimally increase ~7.0 μm/diopter during accommodation. The small equivalent increases in ELRand CLT are associated with a large accommodative amplitude. These findings are consistent with the predictions of mathematical and finite element models that specified the stiffness of the lens nucleus is the same or greater than the lens cortex and that accommodation involves a small force(<5 g).
基金Supported by Ongoing Research Funding Program(ORFFT-2025-054-1),King Saud University,Riyadh,Saudi Arabia.
文摘AIM:To evaluate the efficacy of the total computer vision syndrome questionnaire(CVS-Q)score as a predictive tool for identifying individuals with symptomatic binocular vision anomalies and refractive errors.METHODS:A total of 141 healthy computer users underwent comprehensive clinical visual function assessments,including evaluations of refractive errors,accommodation(amplitude of accommodation,positive relative accommodation,negative relative accommodation,accommodative accuracy,and accommodative facility),and vergence(phoria,positive and negative fusional vergence,near point of convergence,and vergence facility).Total CVS-Q scores were recorded to explore potential associations between symptom scores and the aforementioned clinical visual function parameters.RESULTS:The cohort included 54 males(38.3%)with a mean age of 23.9±0.58y and 87 age-matched females(61.7%)with a mean age of 23.9±0.53y.The multiple regression model was statistically significant[R²=0.60,F=13.28,degrees of freedom(DF=17122,P<0.001].This indicates that 60%of the variance in total CVS-Q scores(reflecting reported symptoms)could be explained by four clinical measurements:amplitude of accommodation,positive relative accommodation,exophoria at distance and near,and positive fusional vergence at near.CONCLUSION:The total CVS-Q score is a valid and reliable tool for predicting the presence of various nonstrabismic binocular vision anomalies and refractive errors in symptomatic computer users.
文摘Psychoeducation is a structured but straightforward and effective treatment,which consists of educating patients and family members about psychiatric disorders,teaching them to cope with the illness,and supporting them during treatment.Psychoeducation as an independent treatment is effective in schizophrenia and bipolar disorder.Psychoeducation is a core component of cognitivebehavioural therapy(CBT)or exposure and response prevention(ERP)treatment,which are the standard psychotherapeutic treatments for obsessive-compulsive disorder(OCD).However,research on the benefits of psychoeducational treatments in OCD is limited compared to schizophrenia and bipolar disorders.Very few studies have examined psychoeducation as an independent treatment for OCD,and its efficacy is not proven.The effectiveness of CBT or ERP for OCD is well established,but the contribution of psychoeducation to the efficacy of these treatments is unclear.Recently,there has been a greater understanding of maladaptive family responses,such as accommodation and antagonism,that worsen the outcome and treatment response in OCD.Family-based psychoeducational treatments targeting inappropriate family responses are effective in reducing obsessional symptoms,attenuating the negative family impact of OCD,and improving patient and family functioning.Family-based psychoeducation is a promising treatment for OCD,but there are methodological issues with the evidence,and trials among adult patients are limited compared to children and adolescents.The other obstacles to the implementation of psychoeducational treatments of OCD are the large treatment gap,lack of research from low-and middle-income countries,and the limited attempts to develop culturally adapted treatments in these countries.Thus,further research should focus on optimising psychoeducational treatments for OCD and efficiently delivering these treatments in routine clinical settings.
基金Financial supports from The National Natural Science Foundation of China (Nos. U22A20109, 52171116 and 52334010)Partial financial support came from The Program for the Central University Youth Innovation TeamThe Fundamental Research Funds for the Central Universities, JLU.
文摘Crystallographic texture engineering is a key strategy for enhancing the mechanical properties of polycrystalline magnesium(Mg)alloys.Due to the intrinsic anisotropy of the hexagonal close-packed(HCP)structure,the deformation behavior of Mg alloys is significantly governed by individual grain deformation and multi-grain interactions,both dictated by crystallographic texture.In the current study,enhanced ductility was achieved in a Mg-Al-Zn-Mn dilute alloy by tailoring a strong basal texture into a transverse-direction-spread elliptical texture through the minor addition of yttrium(Y).Systematic quasi-in-situ electron backscatter diffraction(EBSD)and dislocation/disclination density analyses were performed to examine the microstructural evolution during deformation.We found that disclinations emerge from defect reactions,including dislocation-grain boundary(GB)and twin-GB interactions,which facilitate twinning plasticity and intergranular accommodation in the elliptical-textured alloy,resulting in improved work-hardening capacity and higher ductility(28.5% along the rolling direction and 32.2%along the transverse direction).By introducing disclination analysis to elucidate defect reactions,multi-grain interactions and the associated microstructure-property relationships in polycrystalline metals,our work provides new insights into the design of advanced Mg alloys with enhanced ductility and formability through crystallographic texture engineering.
文摘ISO releases two standards for tourism ISO 9468:2025,Tourism and related services-Online travel agency(OTA)-Guidelines for online accommodation booking platform services,and ISO 25639-1:2025,Exhibitions and events-Part 1:Vocabulary,were released recently,the development of which were led by China.
文摘AIM:To evaluate the effects of refractive errors and binocular vision anomalies on the quality of life(QOL)of university students.METHODS:This cross-sectional analytical study was conducted on university students using simple random sampling.Objective refraction,ocular alignment,vergence and accommodative performance were measured and assessed in all participants.Data on QOL were collected using the College of Optometrists in Vision Development-Quality of Life(COVD-QOL)Questionnaire.The effect of mentioned parameters on the QOL were evaluated.RESULTS:Totally 726 students with mean age of 21.35±1.88y were evaluated in this study,51.5%of whom were female.Esophoria was caused significantly lower QOL in the domains of somatic symptoms and occupationalphysical symptoms(P<0.05);Besides,esotropia decreased QOL in domains of somatic symptoms P=0.002 and psychological factors(P=0.023).Students with accommodation insufficiency experienced more symptoms in all domains(P<0.05)except for psychological factors(P=0.07).Increasing in the near point of convergence and accommodation and decreases QOL and increasing accommodative facility increases QOL(all P<0.05).Myopia and astigmatism cause decrease in QOL(both P<0.05),but hyperopic students had better QOL in comparison with others(P<0.05).CONCLUSION:Screening programs and treatment of refractive errors and binocular vision anomalies,especially phoria and accommodative insufficiency,positively impact the QOL and academic achievements of university students.
文摘The selection of twin variants plays a critical role in shaping the deformation texture and mechanical properties of magnesium alloys that are limited by slip systems and diverse twinning modes.In this study,we investigated the twin variant selection and the effect of twinning activity on the strain hardening of a hot-rolled AZ31 magnesium alloy by quasi-in-situ EBSD.Moreover,the Schmid factors and the displacement gradient tensors were computed to evaluate the activation of twin variants.The results reveal that the yield strength increased progressively after each deformation step,driven by grain subdivision and texture hardening induced by extension{1012}twinning and the Basinski effect at large strains.The nucleation and growth of the{1012}twins occurred either sequentially or simultaneously during the plastic deformation.At low plastic strains,the activation of most twin variants followed the high Schmid factor criterion while the other twin variants with lower Schmid factors were activated due to the interactions with preexisting twins characterized by high misorientation angles(around 60°).Additionally,this non-Schmid factor scenario was also attributed to low coordinated strain requirements from neighboring grains,showing the critical role of local deformation accommodation in the twinning process.These findings advance the fundamental understanding of the twin variant selection and its implications for the microstructure-property relationship in magnesium alloys for structural applications.
基金Supported by the National Natural Science Foundation of China(No.81900910)Natural Science Foundation of Zhejiang Province(No.LQ19H120003)Basic Scientific Research Project of Wenzhou(No.Y20210194,No.Y20190638).
文摘AIM:To explore choroidal thickness(CT)and choroidal vascularity index(CVI)changes around the macula and optic nerve head(ONH)using swept-source optical coherence tomography(SS-OCT)after small-incision lenticule extraction(SMILE)and evaluate their associations with accommodation and aberrations.METHODS:Participants were divided into more myopic group(43 eyes)and less myopic group(33 eyes)according to refractive error.SS-OCT,negative relative accommodation(NRA),and positive relative accommodation(PRA)were analyzed before and 1d,1wk,and 1mo postoperatively.Root mean square higher-order aberrations(RMS HOAs),spherical aberrations(SAs),and coma were compared preoperative,1wk,and 1mo postoperatively.RESULTS:After surgery,RMS(0.29±0.26)and Coma(0.16±0.19)all increased.In the more myopic group,central and T macular CT(247.58±63.81 a n d 276.45±62.52μm)increased.NRA(0.41±0.51)and PRA(0.10±1.30)decreased,and SAs(0.21±0.21)increased.In the less myopic group,all regional and mean macular CT increased.NRA was correlated with mean and inferior CTs and mean ONH CVI.SE was correlated with macular CT,CVI,and ONH CT.Mean macular and ONH CTs were associated with RMS HOA,SA,and coma.Macular T2 CT was a significant predictor of SA.Macular T2 and N1 CT were correlated with coma.CONCLUSION:More variations in accommodation and aberrations and fewer choroid thickens on macular and ONH are found in more myopic eyes after SMILE.Choroidal values are associated with accommodation and aberrations during SMILE.Choroid parameters on SS-OCT varies in eyes with different refractive errors after SMILE and has an association with accommodation and visual quality.
文摘Two international standards on tourism,ISO 9468:2025,Tourism and related services-Online travel agency(OTA)-Guidelines for online accommodation booking platform services,and ISO 25639-1:2025,Exhibitions and events-Part 1:Vocabulary,were recently released by ISO,the development of which was led by China.
文摘Against the backdrop of active global responses to climate change and the accelerated green and low-carbon energy transition,the co-optimization and innovative mechanism design of multimodal energy systems have become a significant instrument for propelling the energy revolution and ensuring energy security.Under increasingly stringent carbon emission constraints,how to achieve multi-dimensional improvements in energy utilization efficiency,renewable energy accommodation levels,and system economics-through the intelligent coupling of diverse energy carriers such as electricity,heat,natural gas,and hydrogen,and the effective application of market-based instruments like carbon trading and demand response-constitutes a critical scientific and engineering challenge demanding urgent solutions.
基金This paper is financially supported by the Scientific Research Foundation of Chongqing University of Technology(Grant Nos.2020ZDZ023 and 2019ZD124)the Project of Science and Technology Research Program of Chongqing Education Commission of China(Grant No.KJQN202101133)the National Natural Science Foundation Cultivation Program of Chongqing University of Technology(Grant No.2021PYZ14).
文摘The asymmetric or periodically varying blade loads resulted by wind shear become more significant as the blade length is increased to capture more wind power.Additionally,compared with the onshore wind turbines,their offshore counterparts are subjected to additional wave loadings in addition to wind loadings within their lifetime.Therefore,vibration control and fatigue load mitigation are crucial for safe operation of large-scale offshore wind turbines.In view of this,a multi-body model of an offshore bottom-fixed wind turbine including a detailed drivetrain is established in this paper.Then,an individual pitch controller(IPC)is designed using disturbance accommodating control.State feedback is used to add damping in flexible modes of concern,and a state estimator is designed to predict unmeasured signals.Continued,a coupled aero-hydro-servo-elastic model is constructed.Based on this coupled model,the load reduction effect of IPC and the dynamic responses of the drivetrain are investigated.The results showed that the designed IPC can effectively reduce the structural loads of the wind turbine while stabilizing the turbine power out-put.Moreover,it is found that the drivetrain dynamic responses are improved under IPC.
文摘My Fair Lady is a movie about how a lower class flower girl turns to an upper class lady by simply changing her language at the help of a linguist.It demonstrates the importance of communication accommodation,especially convergent accommodation,in using language as code and behavior to construct identity in the target community.
文摘Patients with liver cirrhosis exhibit several features of gut dysfunction which may contribute to the development of cirrhosis complications as well as have an impact on nutritional status and health-related quality of life.Gastrointestinal symptoms are common in cirrhosis and their pathophysiology probably involves factors related to liver disease severity,psychological distress,and gut dysfunction(e.g.,increased gastric sensitivity to distension and delayed gut transit).They may lead to reduced food intake and,thus,may contribute to the nutritional status deterioration in cirrhotic patients.Although tense ascites appears to have a negative impact on meal-induced accommodation of the stomach,published data on gastric accommodation in cirrhotics without significant ascites are not unanimous.Gastric emptying and small bowel transit have generally been shown to be prolonged.This may be related to disturbances in postprandial glucose,insulin,and ghrelin levels,which,in turn,appear to be associated to insulin resistance,a common finding in cirrhosis.Furthermore,small bowel manometry disturbances and delayed gut transit may be associated with the development of small bowel bacterial overgrowth.Finally,several studies have reported intestinal barrier dysfunction in patients with cirrhosis(especially those with portal hypertension),which is related to bacterial translocation and permeation of intestinal bacterial products,e.g.,endo-toxin and bacterial DNA,thus potentially being involved in the pathogenesis of complications of liver cirrhosis.
基金Supported by Special Scientific Research Program of Shaanxi Provincial Education Department(No.17JK0662)
文摘AIM： To study effects of orthokeratology（Ortho-k） on accommodation function in myopic children. METHODS： A prospective, non-randomized, case-control study was performed from September to October 2016. Eighty-three children with myopia were divided into two groups. One group was treated with the rigid contact lens for overnight Ortho-k, and the other was treated with single-vision spectacle lens（SVL）. Accommodation function were assessed by accommodative amplitude（AA）, accommodative sensitivity（AS）, accommodative lag（Lag）, negative relative accommodation（NRA）, and positive relative accommodation（PRA） before and 1, 3, 6 and 12 mo after treated. RESULTS： Totally 72 myopic children were finished the follow-up： 37 in Ortho-k group and 35 in SVL group. Wearing time had a significant effect on AA, AS, Lag, and NRA of myopic children in two groups（all P〈0.05）. Meanwhile, there was an interaction effect between wearing time and wearing types（FAA=5.3, FAS=45.5, FLag=7.0, FNRA=3.7, all P〈0.05）. However, the between-group difference of AA（F=0.1）, AS（F=3.2）, Lag（F=1.1）, NRA（F=0.3）, and PRA（F=0.1） showed no significance. AA, AS, NRA, Lag and PRA were improved significantly in Ortho-k group within 1 to 6 mo after wearing. CONCLUSION： Wearing Ortho-k can improve the accommodation function of myopic children, which might be one of the mechanisms for myopia control.
文摘Gastric accommodation is important for the understanding of the pathophysiology in functional dyspepsia and is also relevant for symptom generation in other disorders. The term gastric accommodation has at least three different meanings： The accommodation process, the accommodation reflex, and the accommodation response. The gastric accommodation process is a complex phenomenon that describes how the size of the gastric compartment changes in response to a meal. The electronic barostat is considered the gold standard in assessing gastric accommodation. Imaging methods, including MRI, SPECT, and ultrasonography may also be used, particularly in patients who are stress-responsive, e.g. functional dyspepsia patients, as a non-invasive and less stress-inducing method is favourable. Ultrasonography satisfies these criteria as it does not by itself distort the physiological response in stress-responsive individuals.
基金Supported by A Grant from the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry of China, No. [2008] 101
文摘AIM: To assess the value of ultrasonography (US) in evaluation of proximal gastric accommodation disorder in patients with functional dyspepsia (FD). METHODS: Between April 2011 and March 2012, 45 patients with FD and 27 healthy volunteers were enrolled in this study. Two-dimensional ultrasound (2DUS) and 3-dimensional ultrasound (3DUS) were performed sequentially to measure proximal gastric area (PGA), maximal proximal gastric diameter (MPGD), and proximal gastric volume (PGV). These values were measured separately in the two groups every other 5 min for a duration of 25 min after the beginning of ingestion of a test meal. Air pocket grading was done separately for images of 2DUS and blocks of 3DUS obtained at five scanning time points. RESULTS: Both PGA and PGV of patients were significantly smaller than healthy controls (P = 0.000 and 0.002, respectively). Comparing the two parameters between the groups at each time point, the differences were also statistically significant (P = 0.000-0.013), except at 10 min for the PGV (P = 0.077). However, no overall difference was found between the groups in the MPGD measurements (P = 0.114), though it was statistically significant at a 20-minute examination point (P = 0.026). A total of 360 sets or blocks of images were obtained for both 2DUS and 3DUS. For the images analyzed by 2DUS, none were excluded because of gastric gas, and 50 (13.9%) and 310 (86.1%) sets were determined as air pockets grades 1 and 2, respectively. For the images analyzed by 3DUS, 23 (6.4%) blocks were excluded from the measurement due to presence of a large fundus air pocket (grade 3); fifty (13.9%) and 287 (79.7%) blocks were also graded as 1 and 2, respectively. CONCLUSION: Measurement of both PGA and PGV by 2DUS and 3DUS could be useful for assessment of the proximal gastric accommodation.
