The notion of absolutely clean N-complexes is studied.We show that an N-complex X is absolutely clean if and only if X is Nexact and Z,(X)is an absolutely clean module for each n e Z and i=1,2,..,N.In particular,we pr...The notion of absolutely clean N-complexes is studied.We show that an N-complex X is absolutely clean if and only if X is Nexact and Z,(X)is an absolutely clean module for each n e Z and i=1,2,..,N.In particular,we prove that a bounded above N-complex X is absolutely clean if and only if X,is an absolutely clean module for each n e Z.We also show that under certain hypotheses,an Ncomplex X is Gorenstein AC-injective if and only if Z;(X)is a Gorenstein AC-injective module for each n e Z and t=1,2,.,N.展开更多
We first introduce the concepts of absolutely E-pure modules and E-pure split modules. Then, we characterize the IF rings in terms of absolutely E-pure modules. The E-pure split modules are also characterized.
Entanglement-breaking(EB)subspaces determine the additivity of entanglement of formation(EOF),which is a long-standing issue in quantum information.We explicitly construct the twodimensional EB subspaces of any bipart...Entanglement-breaking(EB)subspaces determine the additivity of entanglement of formation(EOF),which is a long-standing issue in quantum information.We explicitly construct the twodimensional EB subspaces of any bipartite system,when system dimensions are equal,and we apply the subspaces to construct EB spaces of arbitrary dimensions.We also present partial construction when system dimensions are different.Then,we present the notion and properties of EB subspaces for some systems,and in particular the absolute EB subspaces.We construct some examples of absolute EB subspaces,as well as EB subspaces for some systems by using multiqubit Dicke states.展开更多
The optical frequency comb has been widely used in precision measurement. In this study, a multi-peak fitting approach is first proposed to fit the two-photon transition spectrum which overlaps with the neighboring tr...The optical frequency comb has been widely used in precision measurement. In this study, a multi-peak fitting approach is first proposed to fit the two-photon transition spectrum which overlaps with the neighboring transition in Rb-87. The multi-peak fitting approach is used to eliminate the frequency shift affected by the neighboring transition. With locking the carrier envelope offset frequency at 1/4 repetition frequency, the transition frequency is measured to be 770569132739.9 +/- 5.8 kHz, which agrees well with the previous result recommended by Comite International des Poids et Mesures.展开更多
In this paper, we first discuss the methods of comparing two special absolutely convergentsine series, sinnx and sinnx. We state the theorem in.one dimensional case as follows; Theorem. Let be convergent series with n...In this paper, we first discuss the methods of comparing two special absolutely convergentsine series, sinnx and sinnx. We state the theorem in.one dimensional case as follows; Theorem. Let be convergent series with nonnegative terms. SupposeThen for all x∈[0,π]If, in addition, then展开更多
The Absolutely True Diary of a Part-Time Indian is a 2007 National Book Award novel for young adults by Sherman Alexie. Inspired by his own experiences of growing up, award-winning author Sherman Alexie chronicles the...The Absolutely True Diary of a Part-Time Indian is a 2007 National Book Award novel for young adults by Sherman Alexie. Inspired by his own experiences of growing up, award-winning author Sherman Alexie chronicles the contemporary adolescence of one unlucky boy trying to rise above the life everyone expects him to live. As a bildungsroman, the novel honestly depicts the real life in reservation as well as protagonist Arnold's personal development in misfortune. The novel addresses various themes. Through close reading of the novel and with the help of some theories from postcolonial criticism, the present paper tries to analyze the bleak reality of reservation life and protagonist Arnold's struggle for social success, thus interpreting the themes of othering, alienation, unhomeliness, double consciousness, and hope presented in the novel展开更多
It is proved that if μ and v be finite measures on a measurable space (X, S) and v is absolutely continuous with respect to v, then it is holds that L(* S, * μ) L(* S, *v), while L(*S, *μ) and L(*S, V) are the Loeb...It is proved that if μ and v be finite measures on a measurable space (X, S) and v is absolutely continuous with respect to v, then it is holds that L(* S, * μ) L(* S, *v), while L(*S, *μ) and L(*S, V) are the Loeb algebras with respect to measure spaces (X, S,μ) and (X,S,v).展开更多
We develop a rapid and convenient experimental method of absolutely calibrating the transmission of an x-ray flatresponse filter.The calibration experiment is performed on a small laser-target facility,and a set of hi...We develop a rapid and convenient experimental method of absolutely calibrating the transmission of an x-ray flatresponse filter.The calibration experiment is performed on a small laser-target facility,and a set of high resolution holographic flat-field grating spectrometers is used as a discrimination system of the laser-produced x-ray source.Given that the holographic flat-field grating has a relatively large width,the grating is divided into two regions for use in that direction,where one region has the filter added and the other region does not.The filter transmission is determined by dividing the x-ray signal counts detected when the filter is in the line of sight by those detected when the filter is out of the line of sight.We find that the calibration results of this experiment agree with the calibration results using a synchrotron radiation source,as well as simulation results.Our method is not only highly reliable but also rapid and convenient.展开更多
The exit measures of super-Brownian motions with branching mechanism $\psi (z) = z^\alpha ,1< \alpha \leqslant 2$ from a bounded smooth domain D in ?d+1 are known to be absolutely continuous with respect to the sur...The exit measures of super-Brownian motions with branching mechanism $\psi (z) = z^\alpha ,1< \alpha \leqslant 2$ from a bounded smooth domain D in ?d+1 are known to be absolutely continuous with respect to the surface area on ?D if $d< \frac{2}{{a - 1}}$ whereas in the case $d > 1 + \frac{2}{{a - 1}}$ they are singular. However, if the branching is restricted to a singular hyperplane, it is proved that they have absolutely continuous states for alld≥1.展开更多
The single-valued representation of measurable and continuous set-valued map-pings have been discussed in many papers. In this paper we discuss absolutely continuous single-valued representation of absolutely continuo...The single-valued representation of measurable and continuous set-valued map-pings have been discussed in many papers. In this paper we discuss absolutely continuous single-valued representation of absolutely continuous set-valued mappings using the method of constructing polygonal lines.展开更多
This study establishes and validates a method for the precise quantification of aquatic microbial loads using microbial diversity absolute quantitative sequencing.By adding synthetic spike-in DNA to water samples from...This study establishes and validates a method for the precise quantification of aquatic microbial loads using microbial diversity absolute quantitative sequencing.By adding synthetic spike-in DNA to water samples from the Dahei River prior to DNA extraction and 16S rRNA gene sequencing,it generates standard curves to convert sequencing data into absolute microbial copy numbers.The method,which is proved highly accurate(R^(2)>0.99),reveals a clear contrast between the river sites:the upstream community has not only a significantly higher total microbial load but also a completely different makeup of species compared to the downstream site.This approach effectively overcomes the limitations of relative abundance analysis,providing a powerful tool for environmental monitoring,and proposes key steps for future standardization to ensure data comparability and integration.展开更多
BACKGROUND Breast cancer is one of the most prevalent malignancies affecting women worldwide,with approximately 2.3 million new cases diagnosed annually.Breast cancer stem cells(BCSCs)play pivotal roles in tumor initi...BACKGROUND Breast cancer is one of the most prevalent malignancies affecting women worldwide,with approximately 2.3 million new cases diagnosed annually.Breast cancer stem cells(BCSCs)play pivotal roles in tumor initiation,progression,metastasis,therapeutic resistance,and disease recurrence.Cancer stem cells possess selfrenewal capacity,multipotent differentiation potential,and enhanced tumorigenic activity,but their molecular characteristics and regulatory mechanisms require further investigation.AIM To comprehensively characterize the molecular features of BCSCs through multiomics approaches,construct a prognostic prediction model based on stem cellrelated genes,reveal cell-cell communication networks within the tumor microenvironment,and provide theoretical foundation for personalized treatment strategies.METHODS Flow cytometry was employed to detect the expression of BCSC surface markers(CD34,CD45,CD29,CD90,CD105).Transcriptomic analysis was performed to identify differentially expressed genes.Least absolute shrinkage and selection operator regression analysis was utilized to screen key prognostic genes and construct a risk scoring model.Single-cell RNA sequencing and spatial transcriptomics were applied to analyze tumor heterogeneity and spatial gene expression patterns.Cell-cell communication network analysis was conducted to reveal interactions between stem cells and the microenvironment.RESULTS Flow cytometric analysis revealed the highest expression of CD105(96.30%),followed by CD90(68.43%)and CD34(62.64%),while CD29 showed lower expression(7.16%)and CD45 exhibited the lowest expression(1.19%).Transcriptomic analysis identified 3837 significantly differentially expressed genes(1478 upregulated and 2359 downregulated).Least absolute shrinkage and selection operator regression analysis selected 10 key prognostic genes,and the constructed risk scoring model effectively distinguished between high-risk and low-risk patient groups(P<0.001).Single-cell analysis revealed tumor cellular heterogeneity,and spatial transcriptomics demonstrated distinct spatial expression gradients of stem cell-related genes.MED18 gene showed significantly higher expression in malignant tissues(P<0.001)and occupied a central position in cell-cell communication networks,exhibiting significant correlations with tumor cells,macrophages,fibroblasts,and endothelial cells.CONCLUSION This study comprehensively characterized the molecular features of BCSCs through multi-omics approaches,identified reliable surface markers and key regulatory genes,and constructed a prognostic prediction model with clinical application value.展开更多
Multipartite entanglement was not only an interesting phenomenon in quantum physics,but also a key resource in quantum information theory,which can allow for novel quantum advantages in quantum information processing....Multipartite entanglement was not only an interesting phenomenon in quantum physics,but also a key resource in quantum information theory,which can allow for novel quantum advantages in quantum information processing.One of the most striking phenomena in multipartite entangled systems is that even if one acquires complete knowledge of the展开更多
Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and atrophy.The genetic cause of SMA was understood in 1995 when loss or impairment...Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and atrophy.The genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene therapies.SMA was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between individuals.Now,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice versa.Additionally,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.展开更多
基金Supported by the National Natural Science Foundation of China (12061061)Fundamental Research Funds for the Central Universities (31920230173)+1 种基金Longyuan Young Talents of Gansu ProvinceYoung Talents Team Project of Gansu Province (2025QNTD49)。
文摘The notion of absolutely clean N-complexes is studied.We show that an N-complex X is absolutely clean if and only if X is Nexact and Z,(X)is an absolutely clean module for each n e Z and i=1,2,..,N.In particular,we prove that a bounded above N-complex X is absolutely clean if and only if X,is an absolutely clean module for each n e Z.We also show that under certain hypotheses,an Ncomplex X is Gorenstein AC-injective if and only if Z;(X)is a Gorenstein AC-injective module for each n e Z and t=1,2,.,N.
文摘We first introduce the concepts of absolutely E-pure modules and E-pure split modules. Then, we characterize the IF rings in terms of absolutely E-pure modules. The E-pure split modules are also characterized.
文摘Entanglement-breaking(EB)subspaces determine the additivity of entanglement of formation(EOF),which is a long-standing issue in quantum information.We explicitly construct the twodimensional EB subspaces of any bipartite system,when system dimensions are equal,and we apply the subspaces to construct EB spaces of arbitrary dimensions.We also present partial construction when system dimensions are different.Then,we present the notion and properties of EB subspaces for some systems,and in particular the absolute EB subspaces.We construct some examples of absolute EB subspaces,as well as EB subspaces for some systems by using multiqubit Dicke states.
基金Supported by the National Natural Science Foundation of China under Grant Nos 91336103,10934010 and 61078026
文摘The optical frequency comb has been widely used in precision measurement. In this study, a multi-peak fitting approach is first proposed to fit the two-photon transition spectrum which overlaps with the neighboring transition in Rb-87. The multi-peak fitting approach is used to eliminate the frequency shift affected by the neighboring transition. With locking the carrier envelope offset frequency at 1/4 repetition frequency, the transition frequency is measured to be 770569132739.9 +/- 5.8 kHz, which agrees well with the previous result recommended by Comite International des Poids et Mesures.
文摘In this paper, we first discuss the methods of comparing two special absolutely convergentsine series, sinnx and sinnx. We state the theorem in.one dimensional case as follows; Theorem. Let be convergent series with nonnegative terms. SupposeThen for all x∈[0,π]If, in addition, then
文摘The Absolutely True Diary of a Part-Time Indian is a 2007 National Book Award novel for young adults by Sherman Alexie. Inspired by his own experiences of growing up, award-winning author Sherman Alexie chronicles the contemporary adolescence of one unlucky boy trying to rise above the life everyone expects him to live. As a bildungsroman, the novel honestly depicts the real life in reservation as well as protagonist Arnold's personal development in misfortune. The novel addresses various themes. Through close reading of the novel and with the help of some theories from postcolonial criticism, the present paper tries to analyze the bleak reality of reservation life and protagonist Arnold's struggle for social success, thus interpreting the themes of othering, alienation, unhomeliness, double consciousness, and hope presented in the novel
基金Supported by the Special Science Foundation of the Education Committee of Shaanxi Province(03jk066)
文摘It is proved that if μ and v be finite measures on a measurable space (X, S) and v is absolutely continuous with respect to v, then it is holds that L(* S, * μ) L(* S, *v), while L(*S, *μ) and L(*S, V) are the Loeb algebras with respect to measure spaces (X, S,μ) and (X,S,v).
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11405158 and 11775203)the Presidential Foundation of China Academy of Engineering Physics(Grant No.YZJJLX 2016007)
文摘We develop a rapid and convenient experimental method of absolutely calibrating the transmission of an x-ray flatresponse filter.The calibration experiment is performed on a small laser-target facility,and a set of high resolution holographic flat-field grating spectrometers is used as a discrimination system of the laser-produced x-ray source.Given that the holographic flat-field grating has a relatively large width,the grating is divided into two regions for use in that direction,where one region has the filter added and the other region does not.The filter transmission is determined by dividing the x-ray signal counts detected when the filter is in the line of sight by those detected when the filter is out of the line of sight.We find that the calibration results of this experiment agree with the calibration results using a synchrotron radiation source,as well as simulation results.Our method is not only highly reliable but also rapid and convenient.
文摘The exit measures of super-Brownian motions with branching mechanism $\psi (z) = z^\alpha ,1< \alpha \leqslant 2$ from a bounded smooth domain D in ?d+1 are known to be absolutely continuous with respect to the surface area on ?D if $d< \frac{2}{{a - 1}}$ whereas in the case $d > 1 + \frac{2}{{a - 1}}$ they are singular. However, if the branching is restricted to a singular hyperplane, it is proved that they have absolutely continuous states for alld≥1.
文摘The single-valued representation of measurable and continuous set-valued map-pings have been discussed in many papers. In this paper we discuss absolutely continuous single-valued representation of absolutely continuous set-valued mappings using the method of constructing polygonal lines.
基金supported by the National Natural Science Foundation of China(Grant No.32160172)the Key Science-Technology Project of Inner Mongolia(2023KYPT0010)+1 种基金the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Grant No.2025QN03006)the 2023 Inner Mongolia Public Institution High-level Talent Introduction Scientific Research Support Project.
文摘This study establishes and validates a method for the precise quantification of aquatic microbial loads using microbial diversity absolute quantitative sequencing.By adding synthetic spike-in DNA to water samples from the Dahei River prior to DNA extraction and 16S rRNA gene sequencing,it generates standard curves to convert sequencing data into absolute microbial copy numbers.The method,which is proved highly accurate(R^(2)>0.99),reveals a clear contrast between the river sites:the upstream community has not only a significantly higher total microbial load but also a completely different makeup of species compared to the downstream site.This approach effectively overcomes the limitations of relative abundance analysis,providing a powerful tool for environmental monitoring,and proposes key steps for future standardization to ensure data comparability and integration.
基金the Natural Science Foundation of Yongchuan District,No.2023yc-jckx20021.
文摘BACKGROUND Breast cancer is one of the most prevalent malignancies affecting women worldwide,with approximately 2.3 million new cases diagnosed annually.Breast cancer stem cells(BCSCs)play pivotal roles in tumor initiation,progression,metastasis,therapeutic resistance,and disease recurrence.Cancer stem cells possess selfrenewal capacity,multipotent differentiation potential,and enhanced tumorigenic activity,but their molecular characteristics and regulatory mechanisms require further investigation.AIM To comprehensively characterize the molecular features of BCSCs through multiomics approaches,construct a prognostic prediction model based on stem cellrelated genes,reveal cell-cell communication networks within the tumor microenvironment,and provide theoretical foundation for personalized treatment strategies.METHODS Flow cytometry was employed to detect the expression of BCSC surface markers(CD34,CD45,CD29,CD90,CD105).Transcriptomic analysis was performed to identify differentially expressed genes.Least absolute shrinkage and selection operator regression analysis was utilized to screen key prognostic genes and construct a risk scoring model.Single-cell RNA sequencing and spatial transcriptomics were applied to analyze tumor heterogeneity and spatial gene expression patterns.Cell-cell communication network analysis was conducted to reveal interactions between stem cells and the microenvironment.RESULTS Flow cytometric analysis revealed the highest expression of CD105(96.30%),followed by CD90(68.43%)and CD34(62.64%),while CD29 showed lower expression(7.16%)and CD45 exhibited the lowest expression(1.19%).Transcriptomic analysis identified 3837 significantly differentially expressed genes(1478 upregulated and 2359 downregulated).Least absolute shrinkage and selection operator regression analysis selected 10 key prognostic genes,and the constructed risk scoring model effectively distinguished between high-risk and low-risk patient groups(P<0.001).Single-cell analysis revealed tumor cellular heterogeneity,and spatial transcriptomics demonstrated distinct spatial expression gradients of stem cell-related genes.MED18 gene showed significantly higher expression in malignant tissues(P<0.001)and occupied a central position in cell-cell communication networks,exhibiting significant correlations with tumor cells,macrophages,fibroblasts,and endothelial cells.CONCLUSION This study comprehensively characterized the molecular features of BCSCs through multi-omics approaches,identified reliable surface markers and key regulatory genes,and constructed a prognostic prediction model with clinical application value.
基金supported by the China Scholarship Council(Grant No.201608360191)the National Natural Science Foundation of China(Grant Nos.11765016,and 11675113)Jiangxi Education Department Fund(Grant No.KJLD14088)
文摘Multipartite entanglement was not only an interesting phenomenon in quantum physics,but also a key resource in quantum information theory,which can allow for novel quantum advantages in quantum information processing.One of the most striking phenomena in multipartite entangled systems is that even if one acquires complete knowledge of the
基金supported by the Faculty Research Fund(Faculty of Medicine&Health Science,Keele University)Career Development Award–(April 2022)(to SJB)。
文摘Spinal muscular atrophy(SMA)is a genetic condition that results in selective lower motor neuron loss with concomitant muscle weakness and atrophy.The genetic cause of SMA was understood in 1995 when loss or impairment of the survival motor neuron 1(SMN1)gene was identified as the main contributing factor(Lefebvre et al.,1995).This,in combination with the discovery that humans have a“back-up”gene,SMN2,which can produce low levels(approximately 10%)of the full-length functional SMN protein,has led to the generation of SMA-specific gene therapies.SMA was traditionally classified according to age of symptom onset and developmental milestones achieved,with life expectancy and severity varying between individuals.Now,SMN2 copy number is used as a proxy for the prediction of disease severity,with higher SMN2 copy number typically being associated with reduced severity of SMA,although this relationship is not absolute:some individuals with low SMN2 copy number have less severe SMA phenotypes and vice versa.Additionally,the etiology of SMA is further complicated by other factors,such as non-typical nucleotide variants and SMN2-independent modifiers of disease severity.