Nine lignans were isolated and purified by silica gel, ODS, Sephadex LH-20 column chromatographies, preparative HPLC and recrystallization from the aerial parts ofArtemisia absinthium L., and identified as follows： d...Nine lignans were isolated and purified by silica gel, ODS, Sephadex LH-20 column chromatographies, preparative HPLC and recrystallization from the aerial parts ofArtemisia absinthium L., and identified as follows： diayangambin （1）, sesartemin （2）, epiyangambin （3）, （＋）arborone （4）, （-）syringaresinol （5）, epiashchantin （6）, caruilignan C （7）, 7β-caruilignan C （8）, yangambin （9）. Compounds 4, 5, 7, 8 were isolated from this plant for the first time.展开更多
One of the most extensively used herbs in traditional Persian medicine (TPM) used in the treatment ofgastrointestinal (GI) disorders, is the plant Artemisia absinthium Linn. (AAL). It also has a wide range of activiti...One of the most extensively used herbs in traditional Persian medicine (TPM) used in the treatment ofgastrointestinal (GI) disorders, is the plant Artemisia absinthium Linn. (AAL). It also has a wide range of activitiessuch as analgesic and anti-inflammatory, anti-oxidant, anti-fungal, and anti-bacterial activities, hepatoprotective,and neuroprotective activities in addition to having gastroprotective effects. This article is a review comparingTPM resources with new medicines. This review investigates this herb in major TPM sources and strives toextrapolate the exact function it serves in the digestive tract and compares the collected information on the functionof AAL with information found in new medical resource databases such as ISI, Pubmed, Scopus, Google Scholar,and Scientific Information Database. AAL from the Asteraceae family of TPM, known as Afsentin, was used in thetreatment of GI weaknesses, stomach pains, swellings, intestinal parasites, diarrhea, and vomiting. AAL increasedappetite, so it was used for insect repellents and insecticide. Recent studies have indicated that the effects of thisplant improved the symptoms of Crohn's disease and played a role in reducing inflammatory factors. It also hasstrong anti-parasitic, anti-insect, hepatoprotective, and antioxidant effects. Given the widespread use of AAL as atraditional medicine currently in use in different countries, particularly in the treatment of GI diseases, furtherclinical studies that focus on the therapeutic qualities of this plant are required in the future.展开更多
目的:基于特异性聚合酶链式反应(PCR)建立了一种中亚苦蒿药材的鉴别方法,可以准确、便捷地鉴别中亚苦蒿及其近缘种。方法:利用Chloroplast Genome Information Resource(CGIR)数据库查找中亚苦蒿及其近源种叶绿体基因组序列,并筛选获得...目的:基于特异性聚合酶链式反应(PCR)建立了一种中亚苦蒿药材的鉴别方法,可以准确、便捷地鉴别中亚苦蒿及其近缘种。方法:利用Chloroplast Genome Information Resource(CGIR)数据库查找中亚苦蒿及其近源种叶绿体基因组序列,并筛选获得中亚苦蒿特异性单核苷酸多态性(SNP)位点,根据SNP位点设计一对中亚苦蒿特异性鉴别引物zykh1-F和zykh1-R。采集中亚苦蒿及其常见近缘种的原植物样本,建立中亚苦蒿特异性PCR鉴别方法并优化反应体系,对该方法进行耐受性和适用性考察。利用该方法对从新疆药材市场购买中亚苦蒿药材样本进行鉴别。结果:中亚苦蒿特异性PCR鉴别方法采用鉴别引物zykh1-F和zykh1-R,退火温度为54℃、循环次数为33次。经PCR扩增和凝胶电泳后中亚苦蒿在210 bp处可观察到单一明亮条带,其余近缘种如艾、黄花蒿、白叶蒿、野艾蒿均无条带。结论:该研究所建立的中亚苦蒿特异性PCR鉴别方法可准确鉴别中亚苦蒿及其常见近缘种,具有高度特异性,且该方法节约时间和成本,为中亚苦蒿资源引种和利用提供一种方便快捷的物种鉴别方法。展开更多
基金National Natural Science Foundation of China (Grant No. 30973629)
文摘Nine lignans were isolated and purified by silica gel, ODS, Sephadex LH-20 column chromatographies, preparative HPLC and recrystallization from the aerial parts ofArtemisia absinthium L., and identified as follows： diayangambin （1）, sesartemin （2）, epiyangambin （3）, （＋）arborone （4）, （-）syringaresinol （5）, epiashchantin （6）, caruilignan C （7）, 7β-caruilignan C （8）, yangambin （9）. Compounds 4, 5, 7, 8 were isolated from this plant for the first time.
文摘One of the most extensively used herbs in traditional Persian medicine (TPM) used in the treatment ofgastrointestinal (GI) disorders, is the plant Artemisia absinthium Linn. (AAL). It also has a wide range of activitiessuch as analgesic and anti-inflammatory, anti-oxidant, anti-fungal, and anti-bacterial activities, hepatoprotective,and neuroprotective activities in addition to having gastroprotective effects. This article is a review comparingTPM resources with new medicines. This review investigates this herb in major TPM sources and strives toextrapolate the exact function it serves in the digestive tract and compares the collected information on the functionof AAL with information found in new medical resource databases such as ISI, Pubmed, Scopus, Google Scholar,and Scientific Information Database. AAL from the Asteraceae family of TPM, known as Afsentin, was used in thetreatment of GI weaknesses, stomach pains, swellings, intestinal parasites, diarrhea, and vomiting. AAL increasedappetite, so it was used for insect repellents and insecticide. Recent studies have indicated that the effects of thisplant improved the symptoms of Crohn's disease and played a role in reducing inflammatory factors. It also hasstrong anti-parasitic, anti-insect, hepatoprotective, and antioxidant effects. Given the widespread use of AAL as atraditional medicine currently in use in different countries, particularly in the treatment of GI diseases, furtherclinical studies that focus on the therapeutic qualities of this plant are required in the future.
文摘目的:基于特异性聚合酶链式反应(PCR)建立了一种中亚苦蒿药材的鉴别方法,可以准确、便捷地鉴别中亚苦蒿及其近缘种。方法:利用Chloroplast Genome Information Resource(CGIR)数据库查找中亚苦蒿及其近源种叶绿体基因组序列,并筛选获得中亚苦蒿特异性单核苷酸多态性(SNP)位点,根据SNP位点设计一对中亚苦蒿特异性鉴别引物zykh1-F和zykh1-R。采集中亚苦蒿及其常见近缘种的原植物样本,建立中亚苦蒿特异性PCR鉴别方法并优化反应体系,对该方法进行耐受性和适用性考察。利用该方法对从新疆药材市场购买中亚苦蒿药材样本进行鉴别。结果:中亚苦蒿特异性PCR鉴别方法采用鉴别引物zykh1-F和zykh1-R,退火温度为54℃、循环次数为33次。经PCR扩增和凝胶电泳后中亚苦蒿在210 bp处可观察到单一明亮条带,其余近缘种如艾、黄花蒿、白叶蒿、野艾蒿均无条带。结论:该研究所建立的中亚苦蒿特异性PCR鉴别方法可准确鉴别中亚苦蒿及其常见近缘种,具有高度特异性,且该方法节约时间和成本,为中亚苦蒿资源引种和利用提供一种方便快捷的物种鉴别方法。
