颞下颌关节紊乱病（temporom and ibular disorders,TMD）的治疗一直是口腔医学领域比较有争议的问题。文题之所以命名为＂再谈……＂是因在近10余年来笔者曾在我国颞下颌关节病及学的全国会议上谈过几次,且在中华口腔医学杂志等相关...颞下颌关节紊乱病（temporom and ibular disorders,TMD）的治疗一直是口腔医学领域比较有争议的问题。文题之所以命名为＂再谈……＂是因在近10余年来笔者曾在我国颞下颌关节病及学的全国会议上谈过几次,且在中华口腔医学杂志等相关杂志发表过几篇相关的文章。之所以从美国牙科研究学会（American Association for Dental Research,AADR）关于颞下颌关节紊乱病的政策声明谈起,展开更多
The analysis of ancient genomics provides opportunities to explore human population history across both temporal and geographic dimensions(Haak et al.,2015;Wang et al.,2021,2024)to enhance the accessibility and utilit...The analysis of ancient genomics provides opportunities to explore human population history across both temporal and geographic dimensions(Haak et al.,2015;Wang et al.,2021,2024)to enhance the accessibility and utility of these ancient genomic datasets,a range of databases and advanced statistical models have been developed,including the Allen Ancient DNA Resource(AADR)(Mallick et al.,2024)and AdmixTools(Patterson et al.,2012).While upstream processes such as sequencing and raw data processing have been streamlined by resources like the AADR,the downstream analysis of these datasets-encompassing population genetics inference and spatiotemporal interpretation-remains a significant challenge.The AADR provides a unified collection of published ancient DNA(aDNA)data,yet its file-based format and reliance on command-line tools,such as those in Admix-Tools(Patterson et al.,2012),require advanced computational expertise for effective exploration and analysis.These requirements can present significant challenges forresearchers lackingadvanced computational expertise,limiting the accessibility and broader application of these valuable genomic resources.展开更多
文摘颞下颌关节紊乱病（temporom and ibular disorders,TMD）的治疗一直是口腔医学领域比较有争议的问题。文题之所以命名为＂再谈……＂是因在近10余年来笔者曾在我国颞下颌关节病及学的全国会议上谈过几次,且在中华口腔医学杂志等相关杂志发表过几篇相关的文章。之所以从美国牙科研究学会（American Association for Dental Research,AADR）关于颞下颌关节紊乱病的政策声明谈起,
基金by the National Key Research and Development Program of China(2023YFC3303701-02 and 2024YFC3306701)the National Natural Science Foundation of China(T2425014 and 32270667)+3 种基金the Natural Science Foundation of Fujian Province of China(2023J06013)the Major Project of the National Social Science Foundation of China granted to Chuan-Chao Wang(21&ZD285)Open Research Fund of State Key Laboratory of Genetic Engineering at Fudan University(SKLGE-2310)Open Research Fund of Forensic Genetics Key Laboratory of the Ministry of Public Security(2023FGKFKT07).
文摘The analysis of ancient genomics provides opportunities to explore human population history across both temporal and geographic dimensions(Haak et al.,2015;Wang et al.,2021,2024)to enhance the accessibility and utility of these ancient genomic datasets,a range of databases and advanced statistical models have been developed,including the Allen Ancient DNA Resource(AADR)(Mallick et al.,2024)and AdmixTools(Patterson et al.,2012).While upstream processes such as sequencing and raw data processing have been streamlined by resources like the AADR,the downstream analysis of these datasets-encompassing population genetics inference and spatiotemporal interpretation-remains a significant challenge.The AADR provides a unified collection of published ancient DNA(aDNA)data,yet its file-based format and reliance on command-line tools,such as those in Admix-Tools(Patterson et al.,2012),require advanced computational expertise for effective exploration and analysis.These requirements can present significant challenges forresearchers lackingadvanced computational expertise,limiting the accessibility and broader application of these valuable genomic resources.
