Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds tha...Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds that the low-altitude economy can effectively promote the development of high-end and diversified tourism in Zhejiang by innovating tourism formats,optimizing resource allocation,and enhancing tourist experiences.Besides,it analyzes the current development status of the low-altitude economy in Zhejiang and its potential for integration with tourism,revealing specific enabling pathways for tourism transformation,including low-altitude sightseeing,aviation tourism,and low-altitude sports.Finally,it proposes policy recommendations such as strengthening policy support,enhancing infrastructure development,and cultivating market entities.The findings aim to provide theoretical references and practical guidance for the high-quality development of tourism in Zhejiang Province.展开更多
On May 26,40 teachers and students from the graduating class of the Buddhist Academy of Xizang in Lhasa embarked on a teaching practice and national condition study tour in Zhejiang and Shanghai.
A story of how east China’s Zhejiang Province protects and develops its big sea area.DRIVEN by the highly potential“blue market,”China’s coastal provinces are now taking measures to promote marine economy developm...A story of how east China’s Zhejiang Province protects and develops its big sea area.DRIVEN by the highly potential“blue market,”China’s coastal provinces are now taking measures to promote marine economy development.展开更多
BACKGROUND The Zhejiang University(ZJU)index has been demonstrated to have notable value in predicting metabolic dysfunction-associated steatotic liver disease(MASLD)within Chinese populations.However,the correlation ...BACKGROUND The Zhejiang University(ZJU)index has been demonstrated to have notable value in predicting metabolic dysfunction-associated steatotic liver disease(MASLD)within Chinese populations.However,the correlation between the ZJU index and MASLD in type 2 diabetes mellitus(T2DM)patients remains to be elucidated.AIM To investigate the association between the ZJU index and MASLD among patients with T2DM.METHODS This cross-sectional study was conducted on hospitalised patients diagnosed with T2DM.Anthropometric measurements,laboratory data,and ultrasound results were initially collected from all patients.The ZJU index was subsequently calculated.Regression analysis was then used to explore risk factors affecting MASLD,and the optimal ZJU index cut-off value for diagnosing MASLD was determined using restricted cubic spline analysis.Finally,a new model for predicting MASLD in T2DM patients based on the ZJU index was constructed.This model was based on the risk factors identified by regression analysis,and the area under curve values were calculated.The validity and reliability of the models were then compared with each other.RESULTS A total of 688 patients with T2DM were included in this study.A significant positive correlation was identified between the ZJU index and the development of MASLD.Furthermore,the results of the restricted cubic spline analysis showed a non-linear association between ZJU index and MASLD.The ZJU value of 38.87 was identified as the key threshold for diagnosing MASLD.The new predictive model,which was developed by regression analysis,demonstrated a higher diagnostic value for MASLD and exhibited good accuracy in comparison with metabolic indices alone(area under curve=0.76,95%confidence interval:0.72-0.80).CONCLUSION The ZJU index has been shown to be linked to the risk of developing MASLD,and the new model constructed has been shown to possess good predictive value.展开更多
This editorial comments on the study by Tao et al,emphasizing the scalable diagnostic tool for metabolic dysfunction-associated steatotic liver disease(MASLD)in type 2 diabetes mellitus(T2DM).Classical indices such as...This editorial comments on the study by Tao et al,emphasizing the scalable diagnostic tool for metabolic dysfunction-associated steatotic liver disease(MASLD)in type 2 diabetes mellitus(T2DM).Classical indices such as the fatty liver index(FLI),hepatic steatosis index(HSI),and non-alcoholic fatty liver disease-liver fat score have provided valuable insights.Still,their predictive accuracy often varies across populations and clinical settings.In Western cohorts,FLI and HSI are widely applied,yet they depend heavily on anthropometric or categorical variables,which limits their sensitivity in Asian populations.The Zhejiang University index(ZJU index),developed in China,integrates fasting glucose,triglycerides,hepatic enzyme ratios,and body mass index into a composite score of insulin resistance.Recent studies show that the ZJU index outperforms FLI and HSI in predicting MASLD among Chinese patients,particularly those with T2DM,where it demonstrates a nonlinear association with disease risk and identifies a critical threshold of 38.87.The ZJU index links to conditions like sarcopenia,sleep apnea,and gallstones,showing its versatility in metabolic health.This editorial compares its performance with other indices and emphasizes the ZJU index as a nextgeneration tool for MASLD risk stratification globally.展开更多
Across more than a decade of joint Belt and Road Initiative(BRI)promotion,China and Singapore have forged a robust collaboration framework that has yielded substantial results.As the international landscape grows incr...Across more than a decade of joint Belt and Road Initiative(BRI)promotion,China and Singapore have forged a robust collaboration framework that has yielded substantial results.As the international landscape grows increasingly complex,bilateral ties between the two countries continue to strengthen.Leveraging its strategic geographical location,trade connectivity,and developed financial infrastructure,Singapore continues to attract a growing number of Chinese businesses,with over 100,000 entrepreneurs from China’s Zhejiang Province now navigating these changing tides in pursuit of new growth opportunities.Since its inception,the Zhejiang(S)Entrepreneurs Association(ZJEA)has remained committed to promoting resource integration including private capital and talent.It has actively supported Zhejiang entrepreneurs seeking to expand business in Southeast Asia,while also facilitating greater investment by Singaporean companies in Zhejiang.展开更多
The Zhejiang University(ZJU)index,which combines body mass index,fasting blood glucose,triglyceride level and alanine aminotransferase/aspartate aminotransferase ratio,can be used to predict metabolic dysfunction-asso...The Zhejiang University(ZJU)index,which combines body mass index,fasting blood glucose,triglyceride level and alanine aminotransferase/aspartate aminotransferase ratio,can be used to predict metabolic dysfunction-associated steatotic liver disease(MASLD)in patients with type 2 diabetes mellitus(T2DM).The ZJU index of 38.87 has been identified as the key threshold for diagnosing MASLD.The new model for predicting MASLD in T2DM based on ZJU index shows high diagnostic value.While the study is methodologically robust and offers a valuable clinical tool,it is limited by its cross-sectional design,inpatient cohort bias,unadjusted pharmacotherapy effects,and reliance on ultrasound for MASLD diagnosis.Future validation in outpatient settings,incorporating medication data and advanced fibrosis assessment,is crucial to translate this cost-effective biomarker into wide practice.展开更多
[目的]分析2021年浙江省肿瘤登记地区宫颈癌发病、死亡现状及2000—2021年流行趋势。[方法]收集浙江省22个肿瘤登记处上报的宫颈癌发病与死亡资料,计算发病和死亡粗率、中国人口标化率(中标率)、世界人口标化率(世标率)、0~74岁累积率以...[目的]分析2021年浙江省肿瘤登记地区宫颈癌发病、死亡现状及2000—2021年流行趋势。[方法]收集浙江省22个肿瘤登记处上报的宫颈癌发病与死亡资料,计算发病和死亡粗率、中国人口标化率(中标率)、世界人口标化率(世标率)、0~74岁累积率以及35~64岁截缩率等指标。根据2000年全国普查标准人口年龄构成计算中标发病率(age-standardized incidence rate by Chinese standard population,ASIRC)和中标死亡率(age-standardized mortality rate by Chinese standard population,ASMRC),根据Segi世界标准人口年龄构成计算世标发病率(age-standardized incidence rate by world standard population,ASIRW)和世标死亡率(age-standard-ized mortality rate by world standard population,ASMRW)。采用Joinpoint模型分析2000—2021年浙江省肿瘤登记地区宫颈癌发病和死亡趋势,计算年度变化百分比(annual percentage change,APC)、平均年度变化百分比(average annual percentage change,AAPC)及其95%置信区间(confidence interval,CI)。[结果]2021年浙江省肿瘤登记地区女性宫颈癌粗发病率为17.71/10万,ASIRC为11.17/10万,ASIRW为10.27/10万;粗死亡率为4.27/10万,ASMRC为2.11/10万,ASMRW为2.03/10万。年龄别发病与死亡率均随着年龄增长而上升,发病率在50~54岁及70~74岁组出现双高峰,死亡率在80~84岁组出现最高峰。2000—2021年ASIRC总AAPC为4.02%(95%CI:3.07%~4.96%),农村地区ASIRC(AAPC=8.40%,95%CI:6.75%~10.04%)的上升幅度高于城市(AAPC=2.71%,95%CI:1.60%~3.90%)。ASMRC的总AAPC为4.51%(95%CI:2.04%~7.71%),其中2000—2015年呈增长趋势(APC=7.24%,P<0.05),2015—2021年趋势变化无统计学意义(APC=-2.02%,P>0.05)。[结论]2000—2021年浙江省肿瘤登记地区宫颈癌的发病与死亡总体呈上升趋势,其中农村发病率的上升幅度高于城市,防治工作仍需重视。展开更多
Under the background of massive economy which was the typical labor division organization form of Zhejiang Province,the paper had analyzed urbanization characteristics of Zhejiang Province which were rural population ...Under the background of massive economy which was the typical labor division organization form of Zhejiang Province,the paper had analyzed urbanization characteristics of Zhejiang Province which were rural population transference,urbanization promotion along transport corridors,mosaic economy,fuzzy vertical sequence of urbanization system,and county economy surpassing urban economy.And then,the detailed analysis had been conducted on the influence of massive economy on the urbanization in terms of outward foreign direct investment,market competition and industrial structure upgrading,regional directivity of low-level industries,and vertical professional extension and horizontal diversified integration of industries.Finally,it pointed out that the economic social structure of Zhejiang Province was in possession of general characteristics of Desakota mode in transformation,spatial representation and management system,but it also had its own characters in driving mechanism,duty segregation,evolution route and spatial structure.Hence,it needed to regulate and guide urbanization,so that there would be clear urban and rural boundary,intensified land use,reasonable urbanization scale grade and good eco-environment.展开更多
文摘Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds that the low-altitude economy can effectively promote the development of high-end and diversified tourism in Zhejiang by innovating tourism formats,optimizing resource allocation,and enhancing tourist experiences.Besides,it analyzes the current development status of the low-altitude economy in Zhejiang and its potential for integration with tourism,revealing specific enabling pathways for tourism transformation,including low-altitude sightseeing,aviation tourism,and low-altitude sports.Finally,it proposes policy recommendations such as strengthening policy support,enhancing infrastructure development,and cultivating market entities.The findings aim to provide theoretical references and practical guidance for the high-quality development of tourism in Zhejiang Province.
文摘On May 26,40 teachers and students from the graduating class of the Buddhist Academy of Xizang in Lhasa embarked on a teaching practice and national condition study tour in Zhejiang and Shanghai.
文摘A story of how east China’s Zhejiang Province protects and develops its big sea area.DRIVEN by the highly potential“blue market,”China’s coastal provinces are now taking measures to promote marine economy development.
基金Supported by Health Research Program of Anhui,No.AHWJ2023BAc10010Clinical and Translational Research Project of Anhui Province,No.202427b10020078。
文摘BACKGROUND The Zhejiang University(ZJU)index has been demonstrated to have notable value in predicting metabolic dysfunction-associated steatotic liver disease(MASLD)within Chinese populations.However,the correlation between the ZJU index and MASLD in type 2 diabetes mellitus(T2DM)patients remains to be elucidated.AIM To investigate the association between the ZJU index and MASLD among patients with T2DM.METHODS This cross-sectional study was conducted on hospitalised patients diagnosed with T2DM.Anthropometric measurements,laboratory data,and ultrasound results were initially collected from all patients.The ZJU index was subsequently calculated.Regression analysis was then used to explore risk factors affecting MASLD,and the optimal ZJU index cut-off value for diagnosing MASLD was determined using restricted cubic spline analysis.Finally,a new model for predicting MASLD in T2DM patients based on the ZJU index was constructed.This model was based on the risk factors identified by regression analysis,and the area under curve values were calculated.The validity and reliability of the models were then compared with each other.RESULTS A total of 688 patients with T2DM were included in this study.A significant positive correlation was identified between the ZJU index and the development of MASLD.Furthermore,the results of the restricted cubic spline analysis showed a non-linear association between ZJU index and MASLD.The ZJU value of 38.87 was identified as the key threshold for diagnosing MASLD.The new predictive model,which was developed by regression analysis,demonstrated a higher diagnostic value for MASLD and exhibited good accuracy in comparison with metabolic indices alone(area under curve=0.76,95%confidence interval:0.72-0.80).CONCLUSION The ZJU index has been shown to be linked to the risk of developing MASLD,and the new model constructed has been shown to possess good predictive value.
文摘This editorial comments on the study by Tao et al,emphasizing the scalable diagnostic tool for metabolic dysfunction-associated steatotic liver disease(MASLD)in type 2 diabetes mellitus(T2DM).Classical indices such as the fatty liver index(FLI),hepatic steatosis index(HSI),and non-alcoholic fatty liver disease-liver fat score have provided valuable insights.Still,their predictive accuracy often varies across populations and clinical settings.In Western cohorts,FLI and HSI are widely applied,yet they depend heavily on anthropometric or categorical variables,which limits their sensitivity in Asian populations.The Zhejiang University index(ZJU index),developed in China,integrates fasting glucose,triglycerides,hepatic enzyme ratios,and body mass index into a composite score of insulin resistance.Recent studies show that the ZJU index outperforms FLI and HSI in predicting MASLD among Chinese patients,particularly those with T2DM,where it demonstrates a nonlinear association with disease risk and identifies a critical threshold of 38.87.The ZJU index links to conditions like sarcopenia,sleep apnea,and gallstones,showing its versatility in metabolic health.This editorial compares its performance with other indices and emphasizes the ZJU index as a nextgeneration tool for MASLD risk stratification globally.
文摘Across more than a decade of joint Belt and Road Initiative(BRI)promotion,China and Singapore have forged a robust collaboration framework that has yielded substantial results.As the international landscape grows increasingly complex,bilateral ties between the two countries continue to strengthen.Leveraging its strategic geographical location,trade connectivity,and developed financial infrastructure,Singapore continues to attract a growing number of Chinese businesses,with over 100,000 entrepreneurs from China’s Zhejiang Province now navigating these changing tides in pursuit of new growth opportunities.Since its inception,the Zhejiang(S)Entrepreneurs Association(ZJEA)has remained committed to promoting resource integration including private capital and talent.It has actively supported Zhejiang entrepreneurs seeking to expand business in Southeast Asia,while also facilitating greater investment by Singaporean companies in Zhejiang.
文摘The Zhejiang University(ZJU)index,which combines body mass index,fasting blood glucose,triglyceride level and alanine aminotransferase/aspartate aminotransferase ratio,can be used to predict metabolic dysfunction-associated steatotic liver disease(MASLD)in patients with type 2 diabetes mellitus(T2DM).The ZJU index of 38.87 has been identified as the key threshold for diagnosing MASLD.The new model for predicting MASLD in T2DM based on ZJU index shows high diagnostic value.While the study is methodologically robust and offers a valuable clinical tool,it is limited by its cross-sectional design,inpatient cohort bias,unadjusted pharmacotherapy effects,and reliance on ultrasound for MASLD diagnosis.Future validation in outpatient settings,incorporating medication data and advanced fibrosis assessment,is crucial to translate this cost-effective biomarker into wide practice.
文摘[目的]分析2021年浙江省肿瘤登记地区宫颈癌发病、死亡现状及2000—2021年流行趋势。[方法]收集浙江省22个肿瘤登记处上报的宫颈癌发病与死亡资料,计算发病和死亡粗率、中国人口标化率(中标率)、世界人口标化率(世标率)、0~74岁累积率以及35~64岁截缩率等指标。根据2000年全国普查标准人口年龄构成计算中标发病率(age-standardized incidence rate by Chinese standard population,ASIRC)和中标死亡率(age-standardized mortality rate by Chinese standard population,ASMRC),根据Segi世界标准人口年龄构成计算世标发病率(age-standardized incidence rate by world standard population,ASIRW)和世标死亡率(age-standard-ized mortality rate by world standard population,ASMRW)。采用Joinpoint模型分析2000—2021年浙江省肿瘤登记地区宫颈癌发病和死亡趋势,计算年度变化百分比(annual percentage change,APC)、平均年度变化百分比(average annual percentage change,AAPC)及其95%置信区间(confidence interval,CI)。[结果]2021年浙江省肿瘤登记地区女性宫颈癌粗发病率为17.71/10万,ASIRC为11.17/10万,ASIRW为10.27/10万;粗死亡率为4.27/10万,ASMRC为2.11/10万,ASMRW为2.03/10万。年龄别发病与死亡率均随着年龄增长而上升,发病率在50~54岁及70~74岁组出现双高峰,死亡率在80~84岁组出现最高峰。2000—2021年ASIRC总AAPC为4.02%(95%CI:3.07%~4.96%),农村地区ASIRC(AAPC=8.40%,95%CI:6.75%~10.04%)的上升幅度高于城市(AAPC=2.71%,95%CI:1.60%~3.90%)。ASMRC的总AAPC为4.51%(95%CI:2.04%~7.71%),其中2000—2015年呈增长趋势(APC=7.24%,P<0.05),2015—2021年趋势变化无统计学意义(APC=-2.02%,P>0.05)。[结论]2000—2021年浙江省肿瘤登记地区宫颈癌的发病与死亡总体呈上升趋势,其中农村发病率的上升幅度高于城市,防治工作仍需重视。
文摘Under the background of massive economy which was the typical labor division organization form of Zhejiang Province,the paper had analyzed urbanization characteristics of Zhejiang Province which were rural population transference,urbanization promotion along transport corridors,mosaic economy,fuzzy vertical sequence of urbanization system,and county economy surpassing urban economy.And then,the detailed analysis had been conducted on the influence of massive economy on the urbanization in terms of outward foreign direct investment,market competition and industrial structure upgrading,regional directivity of low-level industries,and vertical professional extension and horizontal diversified integration of industries.Finally,it pointed out that the economic social structure of Zhejiang Province was in possession of general characteristics of Desakota mode in transformation,spatial representation and management system,but it also had its own characters in driving mechanism,duty segregation,evolution route and spatial structure.Hence,it needed to regulate and guide urbanization,so that there would be clear urban and rural boundary,intensified land use,reasonable urbanization scale grade and good eco-environment.
