Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds tha...Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds that the low-altitude economy can effectively promote the development of high-end and diversified tourism in Zhejiang by innovating tourism formats,optimizing resource allocation,and enhancing tourist experiences.Besides,it analyzes the current development status of the low-altitude economy in Zhejiang and its potential for integration with tourism,revealing specific enabling pathways for tourism transformation,including low-altitude sightseeing,aviation tourism,and low-altitude sports.Finally,it proposes policy recommendations such as strengthening policy support,enhancing infrastructure development,and cultivating market entities.The findings aim to provide theoretical references and practical guidance for the high-quality development of tourism in Zhejiang Province.展开更多
On May 26,40 teachers and students from the graduating class of the Buddhist Academy of Xizang in Lhasa embarked on a teaching practice and national condition study tour in Zhejiang and Shanghai.
A story of how east China’s Zhejiang Province protects and develops its big sea area.DRIVEN by the highly potential“blue market,”China’s coastal provinces are now taking measures to promote marine economy developm...A story of how east China’s Zhejiang Province protects and develops its big sea area.DRIVEN by the highly potential“blue market,”China’s coastal provinces are now taking measures to promote marine economy development.展开更多
BACKGROUND The Zhejiang University(ZJU)index has been demonstrated to have notable value in predicting metabolic dysfunction-associated steatotic liver disease(MASLD)within Chinese populations.However,the correlation ...BACKGROUND The Zhejiang University(ZJU)index has been demonstrated to have notable value in predicting metabolic dysfunction-associated steatotic liver disease(MASLD)within Chinese populations.However,the correlation between the ZJU index and MASLD in type 2 diabetes mellitus(T2DM)patients remains to be elucidated.AIM To investigate the association between the ZJU index and MASLD among patients with T2DM.METHODS This cross-sectional study was conducted on hospitalised patients diagnosed with T2DM.Anthropometric measurements,laboratory data,and ultrasound results were initially collected from all patients.The ZJU index was subsequently calculated.Regression analysis was then used to explore risk factors affecting MASLD,and the optimal ZJU index cut-off value for diagnosing MASLD was determined using restricted cubic spline analysis.Finally,a new model for predicting MASLD in T2DM patients based on the ZJU index was constructed.This model was based on the risk factors identified by regression analysis,and the area under curve values were calculated.The validity and reliability of the models were then compared with each other.RESULTS A total of 688 patients with T2DM were included in this study.A significant positive correlation was identified between the ZJU index and the development of MASLD.Furthermore,the results of the restricted cubic spline analysis showed a non-linear association between ZJU index and MASLD.The ZJU value of 38.87 was identified as the key threshold for diagnosing MASLD.The new predictive model,which was developed by regression analysis,demonstrated a higher diagnostic value for MASLD and exhibited good accuracy in comparison with metabolic indices alone(area under curve=0.76,95%confidence interval:0.72-0.80).CONCLUSION The ZJU index has been shown to be linked to the risk of developing MASLD,and the new model constructed has been shown to possess good predictive value.展开更多
This editorial comments on the study by Tao et al,emphasizing the scalable diagnostic tool for metabolic dysfunction-associated steatotic liver disease(MASLD)in type 2 diabetes mellitus(T2DM).Classical indices such as...This editorial comments on the study by Tao et al,emphasizing the scalable diagnostic tool for metabolic dysfunction-associated steatotic liver disease(MASLD)in type 2 diabetes mellitus(T2DM).Classical indices such as the fatty liver index(FLI),hepatic steatosis index(HSI),and non-alcoholic fatty liver disease-liver fat score have provided valuable insights.Still,their predictive accuracy often varies across populations and clinical settings.In Western cohorts,FLI and HSI are widely applied,yet they depend heavily on anthropometric or categorical variables,which limits their sensitivity in Asian populations.The Zhejiang University index(ZJU index),developed in China,integrates fasting glucose,triglycerides,hepatic enzyme ratios,and body mass index into a composite score of insulin resistance.Recent studies show that the ZJU index outperforms FLI and HSI in predicting MASLD among Chinese patients,particularly those with T2DM,where it demonstrates a nonlinear association with disease risk and identifies a critical threshold of 38.87.The ZJU index links to conditions like sarcopenia,sleep apnea,and gallstones,showing its versatility in metabolic health.This editorial compares its performance with other indices and emphasizes the ZJU index as a nextgeneration tool for MASLD risk stratification globally.展开更多
Across more than a decade of joint Belt and Road Initiative(BRI)promotion,China and Singapore have forged a robust collaboration framework that has yielded substantial results.As the international landscape grows incr...Across more than a decade of joint Belt and Road Initiative(BRI)promotion,China and Singapore have forged a robust collaboration framework that has yielded substantial results.As the international landscape grows increasingly complex,bilateral ties between the two countries continue to strengthen.Leveraging its strategic geographical location,trade connectivity,and developed financial infrastructure,Singapore continues to attract a growing number of Chinese businesses,with over 100,000 entrepreneurs from China’s Zhejiang Province now navigating these changing tides in pursuit of new growth opportunities.Since its inception,the Zhejiang(S)Entrepreneurs Association(ZJEA)has remained committed to promoting resource integration including private capital and talent.It has actively supported Zhejiang entrepreneurs seeking to expand business in Southeast Asia,while also facilitating greater investment by Singaporean companies in Zhejiang.展开更多
The Zhejiang University(ZJU)index,which combines body mass index,fasting blood glucose,triglyceride level and alanine aminotransferase/aspartate aminotransferase ratio,can be used to predict metabolic dysfunction-asso...The Zhejiang University(ZJU)index,which combines body mass index,fasting blood glucose,triglyceride level and alanine aminotransferase/aspartate aminotransferase ratio,can be used to predict metabolic dysfunction-associated steatotic liver disease(MASLD)in patients with type 2 diabetes mellitus(T2DM).The ZJU index of 38.87 has been identified as the key threshold for diagnosing MASLD.The new model for predicting MASLD in T2DM based on ZJU index shows high diagnostic value.While the study is methodologically robust and offers a valuable clinical tool,it is limited by its cross-sectional design,inpatient cohort bias,unadjusted pharmacotherapy effects,and reliance on ultrasound for MASLD diagnosis.Future validation in outpatient settings,incorporating medication data and advanced fibrosis assessment,is crucial to translate this cost-effective biomarker into wide practice.展开更多
A new genus and species of nodosaurid dinosaur： Zhejiangosaurus lishuiensis gen. et sp. nov. is erected herein. It is characterized by the sacrum consisting of at least three true sacral vertebrae, 5 caudal dorsal ve...A new genus and species of nodosaurid dinosaur： Zhejiangosaurus lishuiensis gen. et sp. nov. is erected herein. It is characterized by the sacrum consisting of at least three true sacral vertebrae, 5 caudal dorsal vertebrae fused to form the presacral rod, wide divergence of long slender preacetabular process of the ilium from the middle line of the body, and the fourth trochanter located at the femoral mid-length.展开更多
Under the background of massive economy which was the typical labor division organization form of Zhejiang Province,the paper had analyzed urbanization characteristics of Zhejiang Province which were rural population ...Under the background of massive economy which was the typical labor division organization form of Zhejiang Province,the paper had analyzed urbanization characteristics of Zhejiang Province which were rural population transference,urbanization promotion along transport corridors,mosaic economy,fuzzy vertical sequence of urbanization system,and county economy surpassing urban economy.And then,the detailed analysis had been conducted on the influence of massive economy on the urbanization in terms of outward foreign direct investment,market competition and industrial structure upgrading,regional directivity of low-level industries,and vertical professional extension and horizontal diversified integration of industries.Finally,it pointed out that the economic social structure of Zhejiang Province was in possession of general characteristics of Desakota mode in transformation,spatial representation and management system,but it also had its own characters in driving mechanism,duty segregation,evolution route and spatial structure.Hence,it needed to regulate and guide urbanization,so that there would be clear urban and rural boundary,intensified land use,reasonable urbanization scale grade and good eco-environment.展开更多
The temporal-spatial distribution features of prehistoric cultures since the Holocene in Zhejiang region were comparatively analyzed based on GIS spatial analysis. Results show that the prehistoric cultures expanded g...The temporal-spatial distribution features of prehistoric cultures since the Holocene in Zhejiang region were comparatively analyzed based on GIS spatial analysis. Results show that the prehistoric cultures expanded gradually in this region before 4000 cal. a BP. The notable expansions occurred twice, one in the Majiabang-Hemudu cultural period, the other in the Liangzhu cultural period. Meanwhile, the prehistoric cultures were disseminated from west to east coast along river valleys. After 4000 cal. a BP, as represented by the Maqiao Culture, the distributed area of each prehistoric culture contracted. This is obviously due to the termination of spreading trends to east coast, which was simultaneously accompanied by two different modes of production and economic transitions in the north and south Zhejiang region respectively. The distribution of prehistoric cultures was closely related with Holocene sea-level fluctuations, especially on the banks of Hangzhou Bay, where the distribution changes of prehistoric cultural sites were greatly affected by sea-level changes, with the closest relationships between them. After 7000 cal. a BP, the process of lowered sea-level and regression-epeirogenesis provided wider terrestrial living spaces for prehistoric inhabi- tants. Based on the comparative analyses of the changes of prehistoric cultures and the en- vironmental evolution information recorded in the Qianmutian subalpine peat of Mt. Tianmu and muddy area on the inner shelf of the East China Sea, it is indicated that the changes of prehistoric cultures were synchronized with environmental changes in Zhejiang region. Before 4000 cal. a BP, the eastward expansion of prehistoric cultures in Zhejiang occurred under the background of the Holocene Optimum, and was the expansion and extension under the joint influences of agricultural civilization and maritime civilization. However, after 4000 cal. a BP, the qeographical contraction of prehistoric cultures in ZheiianQ occurred under the back-ground of dry-cold climate trend and deterioration of coastal marine environment. It is evidenced from the above fact that the development, expansion and contraction of prehistoric cultures are positively correlated to environmental change. The change of the climatic environment is just the underlying reason for these changes and transitions of production modes and economic forms. Therefore, the climatic environment is the dominant factor of prehistoric culture vicissitudes in Zhejiang region, which has exerted great influence on distribution, dissemination, expansion and transmutation of the culture.展开更多
Fossil bamboo leaves and pollen from Upper Miocene deposits of the Shengxian Formation in Tiantai and Ninghai counties, eastern Zhejiang, China represent a rare record in Asia. The distinctive pseudopetiole and parall...Fossil bamboo leaves and pollen from Upper Miocene deposits of the Shengxian Formation in Tiantai and Ninghai counties, eastern Zhejiang, China represent a rare record in Asia. The distinctive pseudopetiole and parallel venation of the leaf blades and the clearly thickened annulus of the pollen aperture place them in the subfamily Bambusoideae. Morphological analysis supports the determination of these fossil leaves as belonging to the genus Bambusium and two new species are described. Bambusium latipseudopetiolus Q.J. Wang et B.N. Sun sp. nov. has a distinctly wide pseudopetiole of 0.23 cm in width and 0.40 cm in length, several vascular bundles on parallel veins, and 5-8 lateral veins on both sides of the midrib. Bambusium longipseudopetiolus Q.J. Wang et B.N. Sun sp. nov. has a distinctly long pseudopetiole of 0.60 cm in length and 0.10 cm in width, several vascular bundles on the pseudopetiole, and 6 lateral veins on both sides of the midrib. Pollen grains from the same layer provide additional evidence of bamboos. They are characterized by 32.0-51.0 μm in diameter, a round pore 3.0-4.0 μm in diameter with a broad thickened annulus 2.5-3.5 μm around, and several conspicuous secondary folds on the exine surface. The morphological analysis leads to their assignment to Graminidites bambusoides Stuchlik. These fossils are important for the study of bamboo phytogeography in China. They demonstrate that there were bamboos growing in southeastern China during the Late Miocene and that bamboos in Zhejiang begin to diversify no later than the Late Miocene. In combination with bamboo fossils from other places, it seems that bamboos had a wide distribution across southern China during the Miocene, ranging from southwestern Yun＇nan to southeastern Zhejiang.展开更多
A new titanosauriform sauropod Dongyangosaurus sinensis gen. et sp. nov. from the early Late Cretaceous of Dongyang County, Zhejiang Province, is erected based on a partial postcranial skeleton. It is characterized by...A new titanosauriform sauropod Dongyangosaurus sinensis gen. et sp. nov. from the early Late Cretaceous of Dongyang County, Zhejiang Province, is erected based on a partial postcranial skeleton. It is characterized by complex laminae on the lateral surface of the neural spines and postzygapophyses of dorsal vertebrae, a distinct fossa on the ventral surfaces of the prezygapophyses of dorsal vertebrae, distinct fossae are also present on the lateral surface of the postzygapophysis of anterior caudal vertebrae; pubis is shorter than ischium, the small obturator foramen of pubis elongated, and nearly closed. The lamina complexity of dorsal vertebrae in Dongyangosaurus indicates that a higher diversity of titanosauriformes occurred during the early Late Cretaceous in China.展开更多
At about 173 ka BP of the late period of mid-Pleistocene, the second terrace of the river had been formed as a result of uplift happening in Shangshan area because of the climate, sea level change and tectonic action....At about 173 ka BP of the late period of mid-Pleistocene, the second terrace of the river had been formed as a result of uplift happening in Shangshan area because of the climate, sea level change and tectonic action. Between 173-75 ka BP, aeolian deposited on the terrace, a layer of reticulate red clayey soil about 80-100 cm thick deposited and developed under the warmer and higher temperature. In the last glacial period, the drop of the temperature and the decrease of the precipitation induced the dust-storms increased, A layer of Xiashu loess about 1.0-1.5 m thick accumulated on Shangshan terrace in the last glacial, which has the reticulate red clayey soil buried. At the beginning of the Holocene （11500 a BP-）, temperature went higher gradually and precipitation got more, the pre-persons moved on the Shangshan terrace （11,400-8600 a BP）, which is one of the most important archaeological sites, and can connect the paleolithic culture with Neolithic culture. It could be assumed from the results that the lower reaches of the Yangtze River are the home of rice cultivation, too. The lower place to the west of the Shangshan site experienced the two cycles process of the fluvial facies and the lacustrine facies, indicating that the water source of the pre-historical Shangshan is the river water or lake water. Two AMS 14C age proved the water source disappeared more than 1000 years ago.展开更多
Jianglang Mountain is situated at the transitional zone of South China fold-system, Jiangshan-Shaoxing deep fracture zone and Baoan-Xiakou-Zhangcun fracture zone. The forming of the Xiakou basin was attributed to the ...Jianglang Mountain is situated at the transitional zone of South China fold-system, Jiangshan-Shaoxing deep fracture zone and Baoan-Xiakou-Zhangcun fracture zone. The forming of the Xiakou basin was attributed to the pull-apart fault depression by the above fractures in earlier Cretaceous, afterward, series deposits such as Guantou formation （K1g）, Chaochuan formation （K1c） and Fangyan formation （K1f） which belong to Yongkang group, the lower Cretaceous layer accumulated in the Xiakou basin. In late Cretaceous, the above fractures occurred to extrude and the basin began to uplift, meanwhile, amounts of tension fissures and joints were produced since Cenozoic, which accelerated water-dicing into bed-rock. Consequently, landform-building processing： weathering, eroding and collapsing etc. were prevalent as finally to develop the so-called Danxia landform. The Jianglang Mountain landscape zone of the Danxia landform to apply for world natural relics are relying on unique and unparalleled peak, sky-split valley with vivid stones and reviving of platform. What is more, there is significance of study at lithology, stratigraphy and paleo-biology. According to dating for specimen of ophitic vein through-crossing the Yongkang group of Yafeng Peak by K-Ar method, this article revealed the uplift age of red-bed basin to be 77.89±2.6 MaBP （K2） i.e. late Cretaceous, and it is the first chronological datum of Danxia landform research in China.展开更多
This paper analyzed the distribution of thermohaline and circulation characteristics of Zhejiang and Fujian waters,based on the cross-sectional thermohaline data and on current data （up to 30 d duration） at fixed-po...This paper analyzed the distribution of thermohaline and circulation characteristics of Zhejiang and Fujian waters,based on the cross-sectional thermohaline data and on current data （up to 30 d duration） at fixed-point moorings,collected in the summer of 2006.We also performed low-pass filtering and spectrum analysis on the mooring submersible buoy data.Based on that analysis,we discussed the characteristics of low frequency currents and time-variations in these waters.The main conclusions are as follows.（1） There is a low salinity pinnate area near the Hangzhou Bay in summer,and outside the low salinity area,an obvious salinity front is present from surface to bottom near 123 E.There is also a temperature front below the surface at a corresponding position.（2） Bottom water of the Taiwan Warm Current comes from the subsurface of Kuroshio.（3） The direction of low frequency current at fixed anchor stations is N-NE or S,which mainly depends on the interaction of control currents in this waters.（4） Significant spectral peaks at all mooring stations are typically semidiurnal and diurnal tides.Semidiurnal tidal waves are the main ones in these waters,and have more energy closer to the shore.（5） Significant energy spectral peaks of middle period （3 to 8 d） of currents are responses to weather frequency.（6） Significant energy spectral peaks of long periods at the surface or bottom are probably responses to seasonal wind or bottom friction,while,the long period peaks of other depths can reflect cyclical changes of interactions between currents.We conclude that the pulsation period of the Taiwan Warm Current in these waters is 10-17 d.展开更多
The amount of several air pollutants emitted in some cities including Hangzhou,Ningbo,Huzhou,Shaoxing and Jiaxing of Zhejiang Province is based on pollution source census data of Zhejiang Province in 2010.This paper f...The amount of several air pollutants emitted in some cities including Hangzhou,Ningbo,Huzhou,Shaoxing and Jiaxing of Zhejiang Province is based on pollution source census data of Zhejiang Province in 2010.This paper focused on the release of air pollutants such as NO_(x2),SO_2,CO,PM2.5,PM10 and VOC,and calculated the total amount of those air pollutants.It analyzed air pollutant emission factors and found that the electricity and heat production industry released the largest amount of pollutants.展开更多
Dongyangopelta yangyanensis gen. et sp. nov. from the Chaochuan Formation （Albian - Cenomanian） of Dongyang, Zhejiang Province, China is characterized： the convex anterior surface of the first presacral rod centrum...Dongyangopelta yangyanensis gen. et sp. nov. from the Chaochuan Formation （Albian - Cenomanian） of Dongyang, Zhejiang Province, China is characterized： the convex anterior surface of the first presacral rod centrum strongly inflates laterally and slightly curves posteriorly; the fused pelvic shield composes of larger pebble-shaped bosses, defined by smaller tubercles or flat stretches of bone; most osteoderms are heavily roughened with notches and grooves for dermal attachment along the edge; domed triradiate osteoderm is present; sigmoid curvature of the dorsal surface of the ilium is present; the preacetabular process curves lateroventraUy at the anterior end and has a shallow groove in the edge of the lateral and anterior ends and strong lateromedial expansion of the distal femur. The femoral head is well separated from the greater trochanter, indicating that Dongyangopeita is a nodosaurid ankylosaur, the second from southeast China. Phylogenetic analysis also positions this taxon in the Nodosauridae clade. Dongyangopelta differs from Zhejiangosaurus in the characters of presacral rod, ilium, and femur. Dongyangopelta represents the first ankylosaur outside North America and Europe that definitively possesses a pelvic shield with fused armor.展开更多
We described a new species, Microhyla beilunensis sp. nov., from Zhejiang Province of China. Phylogenetic analyses based on the mitochondrial 12 S, 16 S and CO1 gene sequences suggested that the new taxon was distinct...We described a new species, Microhyla beilunensis sp. nov., from Zhejiang Province of China. Phylogenetic analyses based on the mitochondrial 12 S, 16 S and CO1 gene sequences suggested that the new taxon was distinctly separated from its congeners and closed to M. mixtura and M. okinavensis. Morphologically, the new species could be identified from its congeners except M. mixtura by several characters：（1） rudimentary webs on toe base;（2） absence of disks and dorsal median longitudinal grooves on finger tips;（3） presence of disks and dorsal median longitudinal grooves on toe tips. As well, the new species could be identified from topotype M. mixtura by the combination of characters：（1） apart from the stripes, bar-shaped and oval-shaped patterns, the rounded spots present on the dorsum of body and legs;（2） the outer metacarpal tubercles prominently larger than the inner one;（3） of males, the ratios of HW, IND, UEW and LAW to SVL of the new species were significantly larger than those of M. mixtura（P 〈 0.01）, and the ratios of SL, IOD, LAHL, HLL, TL, TFL and FL to SVL of the new species were significantly less than those of M. mixtura（P 〈 0.05）.展开更多
The scientific analyses of the spatial patterns of regional eco-environment livability,along with the explorations of the correlations between ecoenvironments and population and economic activity distributions,are of ...The scientific analyses of the spatial patterns of regional eco-environment livability,along with the explorations of the correlations between ecoenvironments and population and economic activity distributions,are of major significance in the guidance of the coordinated development between social economies,natural resources,and environments.In this study,the topography,climate,hydrology,land cover,air quality,and the dangers presented by natural hazards in the study area were investigated in order to establish an evaluation model for the regional eco-environmental livability.Then,the observed spatial patterns and regional differences in the eco-environmental livability,as well as their relationships with the distributions of population and economic activities in Zhejiang Province,were investigated.The results showed that the ecoenvironmental livability in Zhejiang Province displayed a gradual decreasing trend from southwest to northeast,as well as from the mountains to the hills,valleys,and plains areas.During the compartmentalization of the eco-environmental livability,it was observed that the lowest livable area covered the largest population,accounting for approximately 29.64%of the total population in the study area.The higher livable areas covered the widest land areas,accounting for approximately 26.15%of the total area.Moreover,it was found that the eco-environmental livability in the mountain areas was higher than that in the plain areas in Zhejiang Province.Furthermore,the ecoenvironmental livability was found to have a significant exponential relationship with the population and GDP densities of Zhejiang Province,with the R^2 of the curve-fittings reaching 0.835 and 0.656,respectively.However,it was determined that the coefficient of the exponential function was negative,which indicated that a strong negative relationship existed between the eco-environmental livability and densities of the population and economic activities.It was assumed that the impacts of anthropogenic factors were the fundamental causes of this negative correlation.This study introduced two new factors(air quality and natural hazards)into the evaluation framework of eco-environmental livability.As a result,a more comprehensive model was established for the evaluation of eco-environmenta livability in certain segments of the study area Additionally,the correlation between ecoenvironment livability and human activities was discussed in-depth,which can potentially provide theoretical and practical guidance for the implementation of eco-livability in China,and possibly even those of other vast developing countries.展开更多
In this study,an operational forecasting system of sea dike risk in the southern Zhejiang Province,South China was developed based on a coupled storm-surge and wave model.This forecasting system is important because o...In this study,an operational forecasting system of sea dike risk in the southern Zhejiang Province,South China was developed based on a coupled storm-surge and wave model.This forecasting system is important because of the high cost of storm-surge damage and the need for rapid emergency planning.A comparison with astronomical tides in 2016 and the validation of storm surges and high water marks of 20 typhoons verified that the forecast system has a good simulation ability.The system can forecast relatively realistic water levels and wave heights as shown under the parametric atmospheric forces simulated in a case study;the sea dikes in credible high risk were mainly located in the estuaries,rivers,and around the islands in the southern Zhejiang.Therefore,the forecast system is applicable in the southern Zhejiang with a support to the effective prevention from typhoon storm-surge damage.展开更多
文摘Taking Zhejiang Province as an example,this paper explores the mechanisms and implementation pathways through which the low-altitude economy drives the transformation and upgrading of the tourism industry.It finds that the low-altitude economy can effectively promote the development of high-end and diversified tourism in Zhejiang by innovating tourism formats,optimizing resource allocation,and enhancing tourist experiences.Besides,it analyzes the current development status of the low-altitude economy in Zhejiang and its potential for integration with tourism,revealing specific enabling pathways for tourism transformation,including low-altitude sightseeing,aviation tourism,and low-altitude sports.Finally,it proposes policy recommendations such as strengthening policy support,enhancing infrastructure development,and cultivating market entities.The findings aim to provide theoretical references and practical guidance for the high-quality development of tourism in Zhejiang Province.
文摘On May 26,40 teachers and students from the graduating class of the Buddhist Academy of Xizang in Lhasa embarked on a teaching practice and national condition study tour in Zhejiang and Shanghai.
文摘A story of how east China’s Zhejiang Province protects and develops its big sea area.DRIVEN by the highly potential“blue market,”China’s coastal provinces are now taking measures to promote marine economy development.
基金Supported by Health Research Program of Anhui,No.AHWJ2023BAc10010Clinical and Translational Research Project of Anhui Province,No.202427b10020078。
文摘BACKGROUND The Zhejiang University(ZJU)index has been demonstrated to have notable value in predicting metabolic dysfunction-associated steatotic liver disease(MASLD)within Chinese populations.However,the correlation between the ZJU index and MASLD in type 2 diabetes mellitus(T2DM)patients remains to be elucidated.AIM To investigate the association between the ZJU index and MASLD among patients with T2DM.METHODS This cross-sectional study was conducted on hospitalised patients diagnosed with T2DM.Anthropometric measurements,laboratory data,and ultrasound results were initially collected from all patients.The ZJU index was subsequently calculated.Regression analysis was then used to explore risk factors affecting MASLD,and the optimal ZJU index cut-off value for diagnosing MASLD was determined using restricted cubic spline analysis.Finally,a new model for predicting MASLD in T2DM patients based on the ZJU index was constructed.This model was based on the risk factors identified by regression analysis,and the area under curve values were calculated.The validity and reliability of the models were then compared with each other.RESULTS A total of 688 patients with T2DM were included in this study.A significant positive correlation was identified between the ZJU index and the development of MASLD.Furthermore,the results of the restricted cubic spline analysis showed a non-linear association between ZJU index and MASLD.The ZJU value of 38.87 was identified as the key threshold for diagnosing MASLD.The new predictive model,which was developed by regression analysis,demonstrated a higher diagnostic value for MASLD and exhibited good accuracy in comparison with metabolic indices alone(area under curve=0.76,95%confidence interval:0.72-0.80).CONCLUSION The ZJU index has been shown to be linked to the risk of developing MASLD,and the new model constructed has been shown to possess good predictive value.
文摘This editorial comments on the study by Tao et al,emphasizing the scalable diagnostic tool for metabolic dysfunction-associated steatotic liver disease(MASLD)in type 2 diabetes mellitus(T2DM).Classical indices such as the fatty liver index(FLI),hepatic steatosis index(HSI),and non-alcoholic fatty liver disease-liver fat score have provided valuable insights.Still,their predictive accuracy often varies across populations and clinical settings.In Western cohorts,FLI and HSI are widely applied,yet they depend heavily on anthropometric or categorical variables,which limits their sensitivity in Asian populations.The Zhejiang University index(ZJU index),developed in China,integrates fasting glucose,triglycerides,hepatic enzyme ratios,and body mass index into a composite score of insulin resistance.Recent studies show that the ZJU index outperforms FLI and HSI in predicting MASLD among Chinese patients,particularly those with T2DM,where it demonstrates a nonlinear association with disease risk and identifies a critical threshold of 38.87.The ZJU index links to conditions like sarcopenia,sleep apnea,and gallstones,showing its versatility in metabolic health.This editorial compares its performance with other indices and emphasizes the ZJU index as a nextgeneration tool for MASLD risk stratification globally.
文摘Across more than a decade of joint Belt and Road Initiative(BRI)promotion,China and Singapore have forged a robust collaboration framework that has yielded substantial results.As the international landscape grows increasingly complex,bilateral ties between the two countries continue to strengthen.Leveraging its strategic geographical location,trade connectivity,and developed financial infrastructure,Singapore continues to attract a growing number of Chinese businesses,with over 100,000 entrepreneurs from China’s Zhejiang Province now navigating these changing tides in pursuit of new growth opportunities.Since its inception,the Zhejiang(S)Entrepreneurs Association(ZJEA)has remained committed to promoting resource integration including private capital and talent.It has actively supported Zhejiang entrepreneurs seeking to expand business in Southeast Asia,while also facilitating greater investment by Singaporean companies in Zhejiang.
文摘The Zhejiang University(ZJU)index,which combines body mass index,fasting blood glucose,triglyceride level and alanine aminotransferase/aspartate aminotransferase ratio,can be used to predict metabolic dysfunction-associated steatotic liver disease(MASLD)in patients with type 2 diabetes mellitus(T2DM).The ZJU index of 38.87 has been identified as the key threshold for diagnosing MASLD.The new model for predicting MASLD in T2DM based on ZJU index shows high diagnostic value.While the study is methodologically robust and offers a valuable clinical tool,it is limited by its cross-sectional design,inpatient cohort bias,unadjusted pharmacotherapy effects,and reliance on ultrasound for MASLD diagnosis.Future validation in outpatient settings,incorporating medication data and advanced fibrosis assessment,is crucial to translate this cost-effective biomarker into wide practice.
文摘A new genus and species of nodosaurid dinosaur： Zhejiangosaurus lishuiensis gen. et sp. nov. is erected herein. It is characterized by the sacrum consisting of at least three true sacral vertebrae, 5 caudal dorsal vertebrae fused to form the presacral rod, wide divergence of long slender preacetabular process of the ilium from the middle line of the body, and the fourth trochanter located at the femoral mid-length.
文摘Under the background of massive economy which was the typical labor division organization form of Zhejiang Province,the paper had analyzed urbanization characteristics of Zhejiang Province which were rural population transference,urbanization promotion along transport corridors,mosaic economy,fuzzy vertical sequence of urbanization system,and county economy surpassing urban economy.And then,the detailed analysis had been conducted on the influence of massive economy on the urbanization in terms of outward foreign direct investment,market competition and industrial structure upgrading,regional directivity of low-level industries,and vertical professional extension and horizontal diversified integration of industries.Finally,it pointed out that the economic social structure of Zhejiang Province was in possession of general characteristics of Desakota mode in transformation,spatial representation and management system,but it also had its own characters in driving mechanism,duty segregation,evolution route and spatial structure.Hence,it needed to regulate and guide urbanization,so that there would be clear urban and rural boundary,intensified land use,reasonable urbanization scale grade and good eco-environment.
基金National Natural Science Foundation of China, No.41171163 No.41271516+4 种基金 Major Program of National Social Science Foundation of China, No.ll＆ZD183 National Key Technology R＆D Program of China, No.2013BAK08B02 Open Foundation of State Key Laboratory of Lake Science and Environment, Nanjing Institute of Geography ＆ Limnology, CAS, No.2012SKL003 Open Foundation of State Key Laboratory ofLoess and Quaternary Geology, Institute of Earth Environment, CAS, No.SKLLQG1206 Doctoral Scientific Research Foundation of Anhui Normal University, No. 161-070143
文摘The temporal-spatial distribution features of prehistoric cultures since the Holocene in Zhejiang region were comparatively analyzed based on GIS spatial analysis. Results show that the prehistoric cultures expanded gradually in this region before 4000 cal. a BP. The notable expansions occurred twice, one in the Majiabang-Hemudu cultural period, the other in the Liangzhu cultural period. Meanwhile, the prehistoric cultures were disseminated from west to east coast along river valleys. After 4000 cal. a BP, as represented by the Maqiao Culture, the distributed area of each prehistoric culture contracted. This is obviously due to the termination of spreading trends to east coast, which was simultaneously accompanied by two different modes of production and economic transitions in the north and south Zhejiang region respectively. The distribution of prehistoric cultures was closely related with Holocene sea-level fluctuations, especially on the banks of Hangzhou Bay, where the distribution changes of prehistoric cultural sites were greatly affected by sea-level changes, with the closest relationships between them. After 7000 cal. a BP, the process of lowered sea-level and regression-epeirogenesis provided wider terrestrial living spaces for prehistoric inhabi- tants. Based on the comparative analyses of the changes of prehistoric cultures and the en- vironmental evolution information recorded in the Qianmutian subalpine peat of Mt. Tianmu and muddy area on the inner shelf of the East China Sea, it is indicated that the changes of prehistoric cultures were synchronized with environmental changes in Zhejiang region. Before 4000 cal. a BP, the eastward expansion of prehistoric cultures in Zhejiang occurred under the background of the Holocene Optimum, and was the expansion and extension under the joint influences of agricultural civilization and maritime civilization. However, after 4000 cal. a BP, the qeographical contraction of prehistoric cultures in ZheiianQ occurred under the back-ground of dry-cold climate trend and deterioration of coastal marine environment. It is evidenced from the above fact that the development, expansion and contraction of prehistoric cultures are positively correlated to environmental change. The change of the climatic environment is just the underlying reason for these changes and transitions of production modes and economic forms. Therefore, the climatic environment is the dominant factor of prehistoric culture vicissitudes in Zhejiang region, which has exerted great influence on distribution, dissemination, expansion and transmutation of the culture.
基金conducted under the National Natural Science Foundation of China(No.41172022)Specialized Research Fund for the Doctoral Program of Higher Education(Grant No.20120211110022,20100211110019)the Fundamental Research Funds for the Central Universities(No.lzujbky2014-285)
文摘Fossil bamboo leaves and pollen from Upper Miocene deposits of the Shengxian Formation in Tiantai and Ninghai counties, eastern Zhejiang, China represent a rare record in Asia. The distinctive pseudopetiole and parallel venation of the leaf blades and the clearly thickened annulus of the pollen aperture place them in the subfamily Bambusoideae. Morphological analysis supports the determination of these fossil leaves as belonging to the genus Bambusium and two new species are described. Bambusium latipseudopetiolus Q.J. Wang et B.N. Sun sp. nov. has a distinctly wide pseudopetiole of 0.23 cm in width and 0.40 cm in length, several vascular bundles on parallel veins, and 5-8 lateral veins on both sides of the midrib. Bambusium longipseudopetiolus Q.J. Wang et B.N. Sun sp. nov. has a distinctly long pseudopetiole of 0.60 cm in length and 0.10 cm in width, several vascular bundles on the pseudopetiole, and 6 lateral veins on both sides of the midrib. Pollen grains from the same layer provide additional evidence of bamboos. They are characterized by 32.0-51.0 μm in diameter, a round pore 3.0-4.0 μm in diameter with a broad thickened annulus 2.5-3.5 μm around, and several conspicuous secondary folds on the exine surface. The morphological analysis leads to their assignment to Graminidites bambusoides Stuchlik. These fossils are important for the study of bamboo phytogeography in China. They demonstrate that there were bamboos growing in southeastern China during the Late Miocene and that bamboos in Zhejiang begin to diversify no later than the Late Miocene. In combination with bamboo fossils from other places, it seems that bamboos had a wide distribution across southern China during the Miocene, ranging from southwestern Yun＇nan to southeastern Zhejiang.
文摘A new titanosauriform sauropod Dongyangosaurus sinensis gen. et sp. nov. from the early Late Cretaceous of Dongyang County, Zhejiang Province, is erected based on a partial postcranial skeleton. It is characterized by complex laminae on the lateral surface of the neural spines and postzygapophyses of dorsal vertebrae, a distinct fossa on the ventral surfaces of the prezygapophyses of dorsal vertebrae, distinct fossae are also present on the lateral surface of the postzygapophysis of anterior caudal vertebrae; pubis is shorter than ischium, the small obturator foramen of pubis elongated, and nearly closed. The lamina complexity of dorsal vertebrae in Dongyangosaurus indicates that a higher diversity of titanosauriformes occurred during the early Late Cretaceous in China.
基金National Science and Technology Support Program, No.2006BAK21B02 National Basic Research Program of China, No.2003CB415201 National Natural Science Foundation of China, No.40671016
文摘At about 173 ka BP of the late period of mid-Pleistocene, the second terrace of the river had been formed as a result of uplift happening in Shangshan area because of the climate, sea level change and tectonic action. Between 173-75 ka BP, aeolian deposited on the terrace, a layer of reticulate red clayey soil about 80-100 cm thick deposited and developed under the warmer and higher temperature. In the last glacial period, the drop of the temperature and the decrease of the precipitation induced the dust-storms increased, A layer of Xiashu loess about 1.0-1.5 m thick accumulated on Shangshan terrace in the last glacial, which has the reticulate red clayey soil buried. At the beginning of the Holocene （11500 a BP-）, temperature went higher gradually and precipitation got more, the pre-persons moved on the Shangshan terrace （11,400-8600 a BP）, which is one of the most important archaeological sites, and can connect the paleolithic culture with Neolithic culture. It could be assumed from the results that the lower reaches of the Yangtze River are the home of rice cultivation, too. The lower place to the west of the Shangshan site experienced the two cycles process of the fluvial facies and the lacustrine facies, indicating that the water source of the pre-historical Shangshan is the river water or lake water. Two AMS 14C age proved the water source disappeared more than 1000 years ago.
基金National Natural Science Foundation of China, No.40871014The Open Foundation of the State Key Labo-ratory of Loess and Quaternary Geology from the Institute of Earth Environment, CAS, No.SKLLQG0817+2 种基金The Training Foundation of National Basis of Talents, No.J0630535Foundation of Application of the World Natural Heritage from Zhejiang ProvinceFoundation of Modern Analyses Center of Nanjing University
文摘Jianglang Mountain is situated at the transitional zone of South China fold-system, Jiangshan-Shaoxing deep fracture zone and Baoan-Xiakou-Zhangcun fracture zone. The forming of the Xiakou basin was attributed to the pull-apart fault depression by the above fractures in earlier Cretaceous, afterward, series deposits such as Guantou formation （K1g）, Chaochuan formation （K1c） and Fangyan formation （K1f） which belong to Yongkang group, the lower Cretaceous layer accumulated in the Xiakou basin. In late Cretaceous, the above fractures occurred to extrude and the basin began to uplift, meanwhile, amounts of tension fissures and joints were produced since Cenozoic, which accelerated water-dicing into bed-rock. Consequently, landform-building processing： weathering, eroding and collapsing etc. were prevalent as finally to develop the so-called Danxia landform. The Jianglang Mountain landscape zone of the Danxia landform to apply for world natural relics are relying on unique and unparalleled peak, sky-split valley with vivid stones and reviving of platform. What is more, there is significance of study at lithology, stratigraphy and paleo-biology. According to dating for specimen of ophitic vein through-crossing the Yongkang group of Yafeng Peak by K-Ar method, this article revealed the uplift age of red-bed basin to be 77.89±2.6 MaBP （K2） i.e. late Cretaceous, and it is the first chronological datum of Danxia landform research in China.
基金The Public Science and Technology Research Funds Projects of Ocean under contract Nos 200905001,200905010 and 201005019the Research Programs of the Science and Technology Commission of Shanghai under contract No.09DZ1201200the Young Scientist Foundation of the State Oceanic Administration of China under contract No.2011209
文摘This paper analyzed the distribution of thermohaline and circulation characteristics of Zhejiang and Fujian waters,based on the cross-sectional thermohaline data and on current data （up to 30 d duration） at fixed-point moorings,collected in the summer of 2006.We also performed low-pass filtering and spectrum analysis on the mooring submersible buoy data.Based on that analysis,we discussed the characteristics of low frequency currents and time-variations in these waters.The main conclusions are as follows.（1） There is a low salinity pinnate area near the Hangzhou Bay in summer,and outside the low salinity area,an obvious salinity front is present from surface to bottom near 123 E.There is also a temperature front below the surface at a corresponding position.（2） Bottom water of the Taiwan Warm Current comes from the subsurface of Kuroshio.（3） The direction of low frequency current at fixed anchor stations is N-NE or S,which mainly depends on the interaction of control currents in this waters.（4） Significant spectral peaks at all mooring stations are typically semidiurnal and diurnal tides.Semidiurnal tidal waves are the main ones in these waters,and have more energy closer to the shore.（5） Significant energy spectral peaks of middle period （3 to 8 d） of currents are responses to weather frequency.（6） Significant energy spectral peaks of long periods at the surface or bottom are probably responses to seasonal wind or bottom friction,while,the long period peaks of other depths can reflect cyclical changes of interactions between currents.We conclude that the pulsation period of the Taiwan Warm Current in these waters is 10-17 d.
基金supported by the Special Major Science and Technology Project of Zhejiang Province "the Prevention and Control of Regional Haze Weather in Cities of Zhejiang"[projectno.2011C13022]Science and Technology Project of Environmental Protection Bureau of Zhejiang Province "Rulesand Countermeasures of Haze Weather in Zhejiang Province"[project no.200914]
文摘The amount of several air pollutants emitted in some cities including Hangzhou,Ningbo,Huzhou,Shaoxing and Jiaxing of Zhejiang Province is based on pollution source census data of Zhejiang Province in 2010.This paper focused on the release of air pollutants such as NO_(x2),SO_2,CO,PM2.5,PM10 and VOC,and calculated the total amount of those air pollutants.It analyzed air pollutant emission factors and found that the electricity and heat production industry released the largest amount of pollutants.
基金supported by the Joint Dinosaur Investigation Project of the Zhejiang Museum of Natural History, ChinaFukui Prefectural Dinosaur Museum, Japan+1 种基金supported by the Zhejiang Provincial Department of CultureZhejiang Provincial Department of Land Resources
文摘Dongyangopelta yangyanensis gen. et sp. nov. from the Chaochuan Formation （Albian - Cenomanian） of Dongyang, Zhejiang Province, China is characterized： the convex anterior surface of the first presacral rod centrum strongly inflates laterally and slightly curves posteriorly; the fused pelvic shield composes of larger pebble-shaped bosses, defined by smaller tubercles or flat stretches of bone; most osteoderms are heavily roughened with notches and grooves for dermal attachment along the edge; domed triradiate osteoderm is present; sigmoid curvature of the dorsal surface of the ilium is present; the preacetabular process curves lateroventraUy at the anterior end and has a shallow groove in the edge of the lateral and anterior ends and strong lateromedial expansion of the distal femur. The femoral head is well separated from the greater trochanter, indicating that Dongyangopeita is a nodosaurid ankylosaur, the second from southeast China. Phylogenetic analysis also positions this taxon in the Nodosauridae clade. Dongyangopelta differs from Zhejiangosaurus in the characters of presacral rod, ilium, and femur. Dongyangopelta represents the first ankylosaur outside North America and Europe that definitively possesses a pelvic shield with fused armor.
基金supported by National Key Programme of Research and Development, Ministry of Science and Technology (2017YFC0505202)National Natural Sciences Foundation of China (NSFC31471964 and 31201702)+1 种基金Important Research Project of Chinese Academy of Sciences (KJZG-EW-L13)the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA19050201)
文摘We described a new species, Microhyla beilunensis sp. nov., from Zhejiang Province of China. Phylogenetic analyses based on the mitochondrial 12 S, 16 S and CO1 gene sequences suggested that the new taxon was distinctly separated from its congeners and closed to M. mixtura and M. okinavensis. Morphologically, the new species could be identified from its congeners except M. mixtura by several characters：（1） rudimentary webs on toe base;（2） absence of disks and dorsal median longitudinal grooves on finger tips;（3） presence of disks and dorsal median longitudinal grooves on toe tips. As well, the new species could be identified from topotype M. mixtura by the combination of characters：（1） apart from the stripes, bar-shaped and oval-shaped patterns, the rounded spots present on the dorsum of body and legs;（2） the outer metacarpal tubercles prominently larger than the inner one;（3） of males, the ratios of HW, IND, UEW and LAW to SVL of the new species were significantly larger than those of M. mixtura（P 〈 0.01）, and the ratios of SL, IOD, LAHL, HLL, TL, TFL and FL to SVL of the new species were significantly less than those of M. mixtura（P 〈 0.05）.
基金the National Natural Science Foundation of China(No.41901205&41701127)he Natural Science Foundation of Jiangsu Province(No.BK20190482)+1 种基金the Philosophy and Social Science Research Project of Jiangsu University(No.2019SJA0034&2016SJD790012)the Scientific Research Start-up Project of Nanjing University of Science and Technology(No.AE89991/117)。
文摘The scientific analyses of the spatial patterns of regional eco-environment livability,along with the explorations of the correlations between ecoenvironments and population and economic activity distributions,are of major significance in the guidance of the coordinated development between social economies,natural resources,and environments.In this study,the topography,climate,hydrology,land cover,air quality,and the dangers presented by natural hazards in the study area were investigated in order to establish an evaluation model for the regional eco-environmental livability.Then,the observed spatial patterns and regional differences in the eco-environmental livability,as well as their relationships with the distributions of population and economic activities in Zhejiang Province,were investigated.The results showed that the ecoenvironmental livability in Zhejiang Province displayed a gradual decreasing trend from southwest to northeast,as well as from the mountains to the hills,valleys,and plains areas.During the compartmentalization of the eco-environmental livability,it was observed that the lowest livable area covered the largest population,accounting for approximately 29.64%of the total population in the study area.The higher livable areas covered the widest land areas,accounting for approximately 26.15%of the total area.Moreover,it was found that the eco-environmental livability in the mountain areas was higher than that in the plain areas in Zhejiang Province.Furthermore,the ecoenvironmental livability was found to have a significant exponential relationship with the population and GDP densities of Zhejiang Province,with the R^2 of the curve-fittings reaching 0.835 and 0.656,respectively.However,it was determined that the coefficient of the exponential function was negative,which indicated that a strong negative relationship existed between the eco-environmental livability and densities of the population and economic activities.It was assumed that the impacts of anthropogenic factors were the fundamental causes of this negative correlation.This study introduced two new factors(air quality and natural hazards)into the evaluation framework of eco-environmental livability.As a result,a more comprehensive model was established for the evaluation of eco-environmenta livability in certain segments of the study area Additionally,the correlation between ecoenvironment livability and human activities was discussed in-depth,which can potentially provide theoretical and practical guidance for the implementation of eco-livability in China,and possibly even those of other vast developing countries.
基金Supported by the National Key Research and Development Program of China(No.2016YFC1402000)
文摘In this study,an operational forecasting system of sea dike risk in the southern Zhejiang Province,South China was developed based on a coupled storm-surge and wave model.This forecasting system is important because of the high cost of storm-surge damage and the need for rapid emergency planning.A comparison with astronomical tides in 2016 and the validation of storm surges and high water marks of 20 typhoons verified that the forecast system has a good simulation ability.The system can forecast relatively realistic water levels and wave heights as shown under the parametric atmospheric forces simulated in a case study;the sea dikes in credible high risk were mainly located in the estuaries,rivers,and around the islands in the southern Zhejiang.Therefore,the forecast system is applicable in the southern Zhejiang with a support to the effective prevention from typhoon storm-surge damage.
