Objective:To explore the characteristics of ZHANG Zhongjing's medication for constipation by analyzing the prescriptions of treatise on Shanghan Lun and Jingui Yaolue.Methods:the formulations that met the inclusio...Objective:To explore the characteristics of ZHANG Zhongjing's medication for constipation by analyzing the prescriptions of treatise on Shanghan Lun and Jingui Yaolue.Methods:the formulations that met the inclusion criteria were selected to establish a database,and the regularity of ZHANG Zhongjing's medication for constipation was analyzed by the methods of frequency,association rules and clustering.Results:In this study,11 prescriptions and 24 medicines were included.High-frequency use of drugs rhubarb,licorice,CortexMagnoliae Officinalis,fructus aurantii immaturus,mirabilis,ginger,jujube,white atractylodes rhizome,cassia twig,Chinese herbaceous peony.A total of 17 association rules(11 rules for 2 drugs and 6 rules for 3 drugs)were obtained by mining,including"Rhubarb+Mirabilite","fructus aurantii immaturus+Cortex Magnoliae Officinalis","Rhubarb+Cortex Magnoliae Officinalis","Rhubarb+Cortex Magnoliae Officinalis+fructus aurantii immaturus",and so on,and 7 groups of drug pair association group and 2 groups of multi-flavor drug association group were obtained.Network link analysis shows that there are 7 groups of strong link compatibility.Medium link compatibility 46 groups.Cluster analysis obtained 14 groups,including 8 single-taste drug groups,3 drug-pair polymerization groups and 3 multi-taste drug polymerization groups.Conclusions:ZHANG Zhongjing is not only good at using purgative medicine in treating constipation treating constipation,but also pays attention to invigorating qi and activating blood circulation,resolving the surface and regulating dampness,soothing the liver and regulating qi.展开更多
Nowadays,traditional Chinese medicine(TCM)culture and wellness tourism are developing toward integration with an inherent and inevitable basis.A new business mode of TCM wellness tourism bred has emerged,injecting new...Nowadays,traditional Chinese medicine(TCM)culture and wellness tourism are developing toward integration with an inherent and inevitable basis.A new business mode of TCM wellness tourism bred has emerged,injecting new vitality into the development of TCM culture and innovation of tourism.As the cultural representative of TCM industry,Zhang Zhongjing culture should seize the opportunity to make a breakthrough in its brand construction with the help of wellness tourism.The main construction strategies include actively launching books or films and television dramas based on the deeds of Zhang Zhongjing and other famous TCM doctors,turning herbs cultivation bases into special tourism and sightseeing parks,establishing research and dissemination bases of TCM culture,and building TCM wellness tourism bases that integrate learning,rehabilitation,and tourism,using information technology and cultural media platforms to introduce Zhang Zhongjing culture to the world.展开更多
The three chapters in Woman Section of Synopsis of Prescriptions of the Golden Chamber are the earliest medical articles in the diagnosis and treatment of gynecological diseases. They have already had the embryonic fo...The three chapters in Woman Section of Synopsis of Prescriptions of the Golden Chamber are the earliest medical articles in the diagnosis and treatment of gynecological diseases. They have already had the embryonic form of traditional Chinese gynecology,and laid a certain foundation for the future development of gynecology. There are 35 prescriptions in the Woman Section of Synopsis of Prescriptions of the Golden Chamber,using 66 kinds of traditional Chinese medicines and discussing more than 20 kinds of gynecological diseases. There are complete theory,methods,formulas and medicinals,and internal and external therapies. In curing gynecological diseases,the prescriptions are highly characteristic and are worth discussion and learning.展开更多
Gegen Qinlian Decoction is one of the commonly used classical prescriptions,which consists of fourherbs:Gegen(Puerariae Lobatae Radix),Huangqin(Scutellariae Radix),Huanglian(Coptidis Rhizoma),and Zhigancao Glycyrrhiza...Gegen Qinlian Decoction is one of the commonly used classical prescriptions,which consists of fourherbs:Gegen(Puerariae Lobatae Radix),Huangqin(Scutellariae Radix),Huanglian(Coptidis Rhizoma),and Zhigancao Glycyrrhizae Radix et Rhizoma Praeparata cum Melle.The clinical application experience of Gegen Qinlian Decoction is as follows:first,according to Zhongjing Zhang's original text,heat distressing the large intestine with unresolved exterior syndrome is theoriginal meaningof Gegen Qinlian Decoction syndrome.In clinical practice,bacillary dysentery,gastrointestinal cold,etc.,belong to simultaneous exterior and interior disease,which are completely consistent with the original meaning of this prescription;second,the clinical digestive system diseases with exuberant heat of the large intestine as the core manifestation cannot be treated merely based on the exterior syndrome;third,due to the interior-exterior relationship between the lung and the large intestine and between the meridians,the use of Gegen(Puerariae Lobatae Radix),Huangqin(Scutellariae Radix),and Huanglian(Coptidis Rhizoma)can make the source of body clear,and the waste qi can be released and thepore can be easily opened,so this prescription can also be used for exogenous fever;fourth,with multidimensional comprehensive understanding of the syndrome,pathogenesis,symptoms and pharmacology,Gegen Qinlian Decoction has also been further applied to the treatment of hypertension,diabetes,etc.展开更多
This paper introduces the clinical experiences on acupuncture and moxibustion of Zhang Zhongjing, who was regarded as “medical Saint” of Traditional Chinese Medicine. He gave indications for acupuncture and moxibust...This paper introduces the clinical experiences on acupuncture and moxibustion of Zhang Zhongjing, who was regarded as “medical Saint” of Traditional Chinese Medicine. He gave indications for acupuncture and moxibustion, developed robbing fire or inversing fire acupuncture principles to treat febrile diseases. His theories on acupuncture and moxibustion are precious and could be reference in clinical practice.展开更多
By analyzing the structure and academic characteristics of early Western Han medical texts such as Prescriptions for Fifty-Two Diseases(Wu Shi Er Bing Fang)and Prescriptions for Health Preservation(Yang Sheng Fang),an...By analyzing the structure and academic characteristics of early Western Han medical texts such as Prescriptions for Fifty-Two Diseases(Wu Shi Er Bing Fang)and Prescriptions for Health Preservation(Yang Sheng Fang),and considering the development of philosophical thinking during the pre-Qin and Han periods,this study summarizes how Zhongjing Zhang’s Treatise on Cold Damage and Miscellaneous Diseases(Shang Han Za Bing Lun)inherited pre-Qin and Han philosophical thought while further integrating Daoist“natural law”cosmology,Confucian“benevolence”social ethics,and the“isomorphic unity of heaven and humanity”medical theory in Yellow Emperor’s Inner Classic(Huang Di Nei Jing).It proposes health preservation concepts encompassing heaven-human,body-spirit,and benevolence perspectives,along with dietary hygiene,representing the medical embodiment of pre-Han“virtue cultivation”and“body nurturing”life philosophies that profoundly influenced subsequent traditional Chinese medicine health preservation theory and practice.展开更多
Objective The objective of this study was to investigate the preparation process of Mahuang Xixin Fuzi decoction granules based on the clinical pharmacological effects of the classic formulas and to control the qualit...Objective The objective of this study was to investigate the preparation process of Mahuang Xixin Fuzi decoction granules based on the clinical pharmacological effects of the classic formulas and to control the quality of the product.Methods An orthogonal experimental design was used,with extraction yield and transfer rate of key ingredients as evaluation indicators,to optimize the extraction process ofMahuang Xixin Fuzi decoction.The granulation process was optimized based on indicators such as granule formation rate,dissolution rate,and moisture absorption rate.Results The optimal extraction process for Mahuang Xixin Fuzi decoction was determined as the following:using 10 times the amount of water to soak for 30 minutes,extracting three times,each for 60minutes,with a concentrated extract relative density of 1.3 g/mL.A mixture of dextrin and starch at a 1:2 ratio was used as a binder for wet granulation.The granule formation rate,dissolution time,and dilution rate of three repeated batches showed relative standard deviation(RSD)values of 1.48,2.83,and 1.55%.Conclusion This method is stable and feasible,providing valuable data for the industrial production of Mahuang Xixin Fuzi decoction granules and further research on this formulation.展开更多
基金National Natural Science Foundation of China(No.81173171,81573864,81373533).
文摘Objective:To explore the characteristics of ZHANG Zhongjing's medication for constipation by analyzing the prescriptions of treatise on Shanghan Lun and Jingui Yaolue.Methods:the formulations that met the inclusion criteria were selected to establish a database,and the regularity of ZHANG Zhongjing's medication for constipation was analyzed by the methods of frequency,association rules and clustering.Results:In this study,11 prescriptions and 24 medicines were included.High-frequency use of drugs rhubarb,licorice,CortexMagnoliae Officinalis,fructus aurantii immaturus,mirabilis,ginger,jujube,white atractylodes rhizome,cassia twig,Chinese herbaceous peony.A total of 17 association rules(11 rules for 2 drugs and 6 rules for 3 drugs)were obtained by mining,including"Rhubarb+Mirabilite","fructus aurantii immaturus+Cortex Magnoliae Officinalis","Rhubarb+Cortex Magnoliae Officinalis","Rhubarb+Cortex Magnoliae Officinalis+fructus aurantii immaturus",and so on,and 7 groups of drug pair association group and 2 groups of multi-flavor drug association group were obtained.Network link analysis shows that there are 7 groups of strong link compatibility.Medium link compatibility 46 groups.Cluster analysis obtained 14 groups,including 8 single-taste drug groups,3 drug-pair polymerization groups and 3 multi-taste drug polymerization groups.Conclusions:ZHANG Zhongjing is not only good at using purgative medicine in treating constipation treating constipation,but also pays attention to invigorating qi and activating blood circulation,resolving the surface and regulating dampness,soothing the liver and regulating qi.
基金funded by the Henan Provincial Traditional Chinese Medicine Culture and Management Research Project (TCM2022004).
文摘Nowadays,traditional Chinese medicine(TCM)culture and wellness tourism are developing toward integration with an inherent and inevitable basis.A new business mode of TCM wellness tourism bred has emerged,injecting new vitality into the development of TCM culture and innovation of tourism.As the cultural representative of TCM industry,Zhang Zhongjing culture should seize the opportunity to make a breakthrough in its brand construction with the help of wellness tourism.The main construction strategies include actively launching books or films and television dramas based on the deeds of Zhang Zhongjing and other famous TCM doctors,turning herbs cultivation bases into special tourism and sightseeing parks,establishing research and dissemination bases of TCM culture,and building TCM wellness tourism bases that integrate learning,rehabilitation,and tourism,using information technology and cultural media platforms to introduce Zhang Zhongjing culture to the world.
文摘The three chapters in Woman Section of Synopsis of Prescriptions of the Golden Chamber are the earliest medical articles in the diagnosis and treatment of gynecological diseases. They have already had the embryonic form of traditional Chinese gynecology,and laid a certain foundation for the future development of gynecology. There are 35 prescriptions in the Woman Section of Synopsis of Prescriptions of the Golden Chamber,using 66 kinds of traditional Chinese medicines and discussing more than 20 kinds of gynecological diseases. There are complete theory,methods,formulas and medicinals,and internal and external therapies. In curing gynecological diseases,the prescriptions are highly characteristic and are worth discussion and learning.
基金supported by the Project of Traditional Chinese Medicine Academic School Inheritance Workshop Construction of the National Administration of Traditional Chinese Medicine-YanjingLiu's Typhoid Fever School InheritanceWorkshop(LPGZS 2019-01)Projectof Chinese Medicine Master Inheritance Workshop of National Administration of Traditional Chinese Medicine-Qingguo Wang Inheritance Workshaop(2014011)the Sixth Batch of National Chinese Medicine Senior Experts Academic Experience Inheritance Project of National Administration of Traditional Chinese Medicine(2017-01).
文摘Gegen Qinlian Decoction is one of the commonly used classical prescriptions,which consists of fourherbs:Gegen(Puerariae Lobatae Radix),Huangqin(Scutellariae Radix),Huanglian(Coptidis Rhizoma),and Zhigancao Glycyrrhizae Radix et Rhizoma Praeparata cum Melle.The clinical application experience of Gegen Qinlian Decoction is as follows:first,according to Zhongjing Zhang's original text,heat distressing the large intestine with unresolved exterior syndrome is theoriginal meaningof Gegen Qinlian Decoction syndrome.In clinical practice,bacillary dysentery,gastrointestinal cold,etc.,belong to simultaneous exterior and interior disease,which are completely consistent with the original meaning of this prescription;second,the clinical digestive system diseases with exuberant heat of the large intestine as the core manifestation cannot be treated merely based on the exterior syndrome;third,due to the interior-exterior relationship between the lung and the large intestine and between the meridians,the use of Gegen(Puerariae Lobatae Radix),Huangqin(Scutellariae Radix),and Huanglian(Coptidis Rhizoma)can make the source of body clear,and the waste qi can be released and thepore can be easily opened,so this prescription can also be used for exogenous fever;fourth,with multidimensional comprehensive understanding of the syndrome,pathogenesis,symptoms and pharmacology,Gegen Qinlian Decoction has also been further applied to the treatment of hypertension,diabetes,etc.
文摘This paper introduces the clinical experiences on acupuncture and moxibustion of Zhang Zhongjing, who was regarded as “medical Saint” of Traditional Chinese Medicine. He gave indications for acupuncture and moxibustion, developed robbing fire or inversing fire acupuncture principles to treat febrile diseases. His theories on acupuncture and moxibustion are precious and could be reference in clinical practice.
基金supported by the Henan Provincial Traditional Chinese Medicine Culture and Management Research Project(TCM2022036)Henan Provincial Traditional Chinese Medicine Culture Publication Funding Special Project(TCMCB2023016)+3 种基金Henan University of Chinese Medicine Research Seedling Project(MP2023-29)National Administration of Traditional Chinese Medicine Science and Technology Project(GZY-KJS-2022-043-1)Henan Culture-Promoting Project Cultural Research Special Project(2022XWH231)National Administration of Traditional Chinese Medicine Science and Technology Project(GZY-KJS-2022-037).
文摘By analyzing the structure and academic characteristics of early Western Han medical texts such as Prescriptions for Fifty-Two Diseases(Wu Shi Er Bing Fang)and Prescriptions for Health Preservation(Yang Sheng Fang),and considering the development of philosophical thinking during the pre-Qin and Han periods,this study summarizes how Zhongjing Zhang’s Treatise on Cold Damage and Miscellaneous Diseases(Shang Han Za Bing Lun)inherited pre-Qin and Han philosophical thought while further integrating Daoist“natural law”cosmology,Confucian“benevolence”social ethics,and the“isomorphic unity of heaven and humanity”medical theory in Yellow Emperor’s Inner Classic(Huang Di Nei Jing).It proposes health preservation concepts encompassing heaven-human,body-spirit,and benevolence perspectives,along with dietary hygiene,representing the medical embodiment of pre-Han“virtue cultivation”and“body nurturing”life philosophies that profoundly influenced subsequent traditional Chinese medicine health preservation theory and practice.
基金funded by the Henan Province 2024 Science and Technology Development Plan Science and Technology Key Project(242102310577).
文摘Objective The objective of this study was to investigate the preparation process of Mahuang Xixin Fuzi decoction granules based on the clinical pharmacological effects of the classic formulas and to control the quality of the product.Methods An orthogonal experimental design was used,with extraction yield and transfer rate of key ingredients as evaluation indicators,to optimize the extraction process ofMahuang Xixin Fuzi decoction.The granulation process was optimized based on indicators such as granule formation rate,dissolution rate,and moisture absorption rate.Results The optimal extraction process for Mahuang Xixin Fuzi decoction was determined as the following:using 10 times the amount of water to soak for 30 minutes,extracting three times,each for 60minutes,with a concentrated extract relative density of 1.3 g/mL.A mixture of dextrin and starch at a 1:2 ratio was used as a binder for wet granulation.The granule formation rate,dissolution time,and dilution rate of three repeated batches showed relative standard deviation(RSD)values of 1.48,2.83,and 1.55%.Conclusion This method is stable and feasible,providing valuable data for the industrial production of Mahuang Xixin Fuzi decoction granules and further research on this formulation.
