BACKGROUND There are only a few studies on the influence of economic inequalities on youngonset type 2 diabetes(T2D).AIM To examine the impact of different family incomes on the development of youngonset T2D.METHODS W...BACKGROUND There are only a few studies on the influence of economic inequalities on youngonset type 2 diabetes(T2D).AIM To examine the impact of different family incomes on the development of youngonset T2D.METHODS We identified 7505336 young adults aged 20-39 years from the 2008 Taiwan region Health Insurance Research Database,China.The young adults were divided into low-income,middle-income,and high-income groups.Cox proportional hazards models were used to determine the risks of young-onset T2D and all-cause mortality in low-income and middle-income groups compared with the highincome group.RESULTS With a mean follow-up of 8.0 years,the incidence rates of young-onset T2D were 3.39,3.10,and 2.88 per 1000 person-years in the low-income,middle-income,and high-income groups,respectively.Compared with the high-income group,the risk of young-onset T2D was significantly higher in the low-income[adjusted hazard ratio(aHR)(95%CI):1.46(1.44–1.48)]and middle-income[aHR(95%CI):1.29(1.27–1.31)]groups.All-cause mortality was also higher in the low-income[aHR(95%CI):2.79(2.70–2.88)]and middle-income[aHR(95%CI):1.59(1.53–1.65)]groups.Older age,male sex,obesity,smoking,alcohol-related disorders,hypertension,dyslipidemia,gout,and psychotic disorders were significantly associated with increased risks of both young-onset T2D and mortality.CONCLUSION This nationwide cohort study demonstrated that young people from low-income and middle-income groups had a higher risk of youth-onset T2D and mortality than those from the high-income group.展开更多
基金Supported by Taipei Veterans General Hospital,No.V113C-166 and No.V114C-177National Science and Technology Council,R.O.C,No.NSTC113-2314-B-075-007-.
文摘BACKGROUND There are only a few studies on the influence of economic inequalities on youngonset type 2 diabetes(T2D).AIM To examine the impact of different family incomes on the development of youngonset T2D.METHODS We identified 7505336 young adults aged 20-39 years from the 2008 Taiwan region Health Insurance Research Database,China.The young adults were divided into low-income,middle-income,and high-income groups.Cox proportional hazards models were used to determine the risks of young-onset T2D and all-cause mortality in low-income and middle-income groups compared with the highincome group.RESULTS With a mean follow-up of 8.0 years,the incidence rates of young-onset T2D were 3.39,3.10,and 2.88 per 1000 person-years in the low-income,middle-income,and high-income groups,respectively.Compared with the high-income group,the risk of young-onset T2D was significantly higher in the low-income[adjusted hazard ratio(aHR)(95%CI):1.46(1.44–1.48)]and middle-income[aHR(95%CI):1.29(1.27–1.31)]groups.All-cause mortality was also higher in the low-income[aHR(95%CI):2.79(2.70–2.88)]and middle-income[aHR(95%CI):1.59(1.53–1.65)]groups.Older age,male sex,obesity,smoking,alcohol-related disorders,hypertension,dyslipidemia,gout,and psychotic disorders were significantly associated with increased risks of both young-onset T2D and mortality.CONCLUSION This nationwide cohort study demonstrated that young people from low-income and middle-income groups had a higher risk of youth-onset T2D and mortality than those from the high-income group.
