Objective:To investigate the anticancer activity of the total flavonoids isolated from a herbal formula,Xianhe Yanling Recipe(仙鹤延龄方),a recipe commonly used in cancer patients in China.Methods: The in vitro an...Objective:To investigate the anticancer activity of the total flavonoids isolated from a herbal formula,Xianhe Yanling Recipe(仙鹤延龄方),a recipe commonly used in cancer patients in China.Methods: The in vitro anticancer activity of the total flavonoids was determined using the 3-(4,5-dimethylthiazole-2-yl)-2,5- diphenyltetrazolium bromide(MTT) assay on three cancer cell lines:MCF-7(a human breast adenocarcinoma cell line),HepG-2(a human hepatocellular carcinoma cell line) and ES-2(a human ovarian cancer cell line). The in vivo anticancer effect of the total flavonoids was assessed in a mouse tumor model bearing H22-induced hepatocellular carcinoma,and cisplatin was used as a positive control.Results:The total flavonoids exerted a powerful inhibitory effect on the three cell lines,with 50%inhibiting concentrations(IC_(50)) of 24.948,31.569 and 6.923μg/mL,respectively.In vivo studies showed that the total flavonoids had dose-dependent inhibitory effects on hepatocellular carcinoma in mice.Conclusion:The total flavonoids from Xianhe Yanling Recipe have potential anticancer activity,and further researches and development are warranted.展开更多
The paper had illustrated the construction of Yanling Famous Flowers and Trees Science Park and highlighted its important position as scalized,standardized and corporatization demonstration based on development of flo...The paper had illustrated the construction of Yanling Famous Flowers and Trees Science Park and highlighted its important position as scalized,standardized and corporatization demonstration based on development of flower industry and basic condition of the park.Through interview and sample survey of flower enterprises,it concluded that the park had vigorous support from government,good service concept,strong consciousness for developing flowers tourism,and scaled development.And meantime,it pointed out three problems in park's management which were problems about enterprise's flower production characteristic,about the concept of farmers of land transference,and about enterprises.Finally,from the perspective of park's management,it put forward some suggestions on flowers tourism development.In terms of flowers tourism development,it should enhance characterization,scale and standardization of enterprises production,explore diversified methods for land transference,and strengthen peasant-workers' skill and thought training.In terms of supportive policy,it should intensify the park's identification,pay attention to protection of ecological environment,create tourist products of local feature,enhance publicity and highlight participation and experience projects.展开更多
文摘Objective:To investigate the anticancer activity of the total flavonoids isolated from a herbal formula,Xianhe Yanling Recipe(仙鹤延龄方),a recipe commonly used in cancer patients in China.Methods: The in vitro anticancer activity of the total flavonoids was determined using the 3-(4,5-dimethylthiazole-2-yl)-2,5- diphenyltetrazolium bromide(MTT) assay on three cancer cell lines:MCF-7(a human breast adenocarcinoma cell line),HepG-2(a human hepatocellular carcinoma cell line) and ES-2(a human ovarian cancer cell line). The in vivo anticancer effect of the total flavonoids was assessed in a mouse tumor model bearing H22-induced hepatocellular carcinoma,and cisplatin was used as a positive control.Results:The total flavonoids exerted a powerful inhibitory effect on the three cell lines,with 50%inhibiting concentrations(IC_(50)) of 24.948,31.569 and 6.923μg/mL,respectively.In vivo studies showed that the total flavonoids had dose-dependent inhibitory effects on hepatocellular carcinoma in mice.Conclusion:The total flavonoids from Xianhe Yanling Recipe have potential anticancer activity,and further researches and development are warranted.
文摘The paper had illustrated the construction of Yanling Famous Flowers and Trees Science Park and highlighted its important position as scalized,standardized and corporatization demonstration based on development of flower industry and basic condition of the park.Through interview and sample survey of flower enterprises,it concluded that the park had vigorous support from government,good service concept,strong consciousness for developing flowers tourism,and scaled development.And meantime,it pointed out three problems in park's management which were problems about enterprise's flower production characteristic,about the concept of farmers of land transference,and about enterprises.Finally,from the perspective of park's management,it put forward some suggestions on flowers tourism development.In terms of flowers tourism development,it should enhance characterization,scale and standardization of enterprises production,explore diversified methods for land transference,and strengthen peasant-workers' skill and thought training.In terms of supportive policy,it should intensify the park's identification,pay attention to protection of ecological environment,create tourist products of local feature,enhance publicity and highlight participation and experience projects.