From June 4 to 17,2025,the Harmony Together for a Friendly Future-Exhibition of Intermitioncil Youth Photography,jointly hosted by China Center of International Cultural Exchange and Tourism Promotion(CETP)nnd China C...From June 4 to 17,2025,the Harmony Together for a Friendly Future-Exhibition of Intermitioncil Youth Photography,jointly hosted by China Center of International Cultural Exchange and Tourism Promotion(CETP)nnd China Cultural Center in Copenhagen,was successfully held at the China Cultured Center in Copenhagen.展开更多
The ITU Global Youth Celebration(GYC-25)is more than just a celebration.It reaffirms our commitment to youth as essential partners in building a connected,inclusive,and sustainable digital future.This is where bold id...The ITU Global Youth Celebration(GYC-25)is more than just a celebration.It reaffirms our commitment to youth as essential partners in building a connected,inclusive,and sustainable digital future.This is where bold ideas meet real action.Get ready for an electrifying mix of inspiration,learning,and co-creation all fueled by youth leadership and digital innovation.展开更多
Youth representatives from 13 countries gathered in Jinshan Peach Orchard,where a local farmer introduced them to the centuriesold history of flat peach cultivation.Through their lenses,they documented a fusion of tra...Youth representatives from 13 countries gathered in Jinshan Peach Orchard,where a local farmer introduced them to the centuriesold history of flat peach cultivation.Through their lenses,they documented a fusion of traditional wisdom and modern agricultural technology-a living narrative of agricultural progress that connects the past to the present.展开更多
On April 19th,"the Youth Table Tennis Programme—Photo Exhibition of Zhou Enlai and the Bandung Conference&China-ASEAN(Indonesia)Youth Table Tennis Training Camp"opened in Jakarta,Indonesia.The event was...On April 19th,"the Youth Table Tennis Programme—Photo Exhibition of Zhou Enlai and the Bandung Conference&China-ASEAN(Indonesia)Youth Table Tennis Training Camp"opened in Jakarta,Indonesia.The event was guided by the Chinese Embassy in Indonesia and co-organised by the ASEAN-China Centre(ACC),the Memorial to Zhou Enlai and Deng Yingchao,the China Friendship Foundation for Peace and Development,the Beijing One Heart Sphere Charity Foundation,and the Enlai Foundation.展开更多
Aging is a pivotal risk factor for intervertebral disc degeneration(IVDD)and chronic low back pain(LBP).The restoration of aging nucleus pulposus cells(NPCs)to a youthful epigenetic state is crucial for IVDD treatment...Aging is a pivotal risk factor for intervertebral disc degeneration(IVDD)and chronic low back pain(LBP).The restoration of aging nucleus pulposus cells(NPCs)to a youthful epigenetic state is crucial for IVDD treatment,but remains a formidable challenge.Here,we proposed a strategy to partially reprogram and reinstate youthful epigenetics of senescent NPCs by delivering a plasmid carrier that expressed pluripotency-associated genes(Oct4,Klf4 and Sox2)in Cavin2-modified exosomes(OKS@M-Exo)for treatment of IVDD and alleviating LBP.The functional OKS@M-Exo efficaciously alleviated senescence markers(p16^(INK4a),p21^(CIP1)and p53),reduced DNA damage and H4K20me3 expression,as well as restored proliferation ability and metabolic balance in senescent NPCs,as validated through in vitro experiments.In a rat model of IVDD,OKS@M-Exo maintained intervertebral disc height,nucleus pulposus hydration and tissue structure,effectively ameliorated IVDD via decreasing the senescence markers.Additionally,OKS@MExo reduced nociceptive behavior and downregulated nociception markers,indicating its efficiency in alleviating LBP.The transcriptome sequencing analysis also demonstrated that OKS@M-Exo could decrease the expression of age-related pathways and restore cell proliferation.Collectively,reprogramming by the OKS@M-Exo to restore youthful epigenetics of senescent NPCs may hold promise as a therapeutic platform to treat IVDD.展开更多
On the evening of May 30th,the parallel forum"Youth Power in Dialogue among Civilisations,"as part of the 4th Dialogue on Exchanges and Mutual Learning among Civilisations,was held in Dunhuang.The forum was ...On the evening of May 30th,the parallel forum"Youth Power in Dialogue among Civilisations,"as part of the 4th Dialogue on Exchanges and Mutual Learning among Civilisations,was held in Dunhuang.The forum was hosted by the Chinese Association for International Understanding and organised by the Schwarzman College of Tsinghua University.More than 30 youth representatives from the Schwarzman Scholars international delegation and a delegation of European,American and African NGO friends came together under the theme"The Youth Power of Cross-Civilisation Dialogue.Discussions focused on topics such as cultural inheritance and innovation,and cross-cultural collaboration.The sessions were co-chaired by Professor Pan Qingzhong,Executive Dean of the Schwarzman College,and Joshua Woodard,a Schwarzman Scholar from the United States of America.展开更多
This article has been compiled and edited by China Report ASEAN based on an interview with the FAO Office of Youth and Women.As the Food and Agriculture Organization of the United Nations(FAO)celebrates its 80th anniv...This article has been compiled and edited by China Report ASEAN based on an interview with the FAO Office of Youth and Women.As the Food and Agriculture Organization of the United Nations(FAO)celebrates its 80th anniversary,the spotlight is shifting from solely honouring its longstanding mission to also highlighting the dynamic participation of youth and women in driving positive changes in agrifood systems.展开更多
From June 4 to 17,2025.the Harmony Together for Friendly future-Exhibition of International Youth Photography.jointly Hosted by China Center for International Culture and Tourism Exchanges(CCICTE) and China Cultural C...From June 4 to 17,2025.the Harmony Together for Friendly future-Exhibition of International Youth Photography.jointly Hosted by China Center for International Culture and Tourism Exchanges(CCICTE) and China Cultural Center in Copenhagen.展开更多
Background:Physicalfitness in childhood and adolescence is associated with a variety of health outcomes and is a powerful marker of current and future health.However,inconsistencies in tests and protocols limit interna...Background:Physicalfitness in childhood and adolescence is associated with a variety of health outcomes and is a powerful marker of current and future health.However,inconsistencies in tests and protocols limit international monitoring and surveillance.The objective of the study was to seek international consensus on a proposed,evidence-informed,Youth Fitness International Test(YFIT)battery and protocols for health monitoring and surveillance in children and adolescents aged 618 years.Methods:We conducted an international modified Delphi study to evaluate the level of agreement with a proposed,evidence-based,YFIT of core health-relatedfitness tests and protocols to be used worldwide in 6-to 18-year-olds.This proposal was based on previous European and North American projects that systematically reviewed the existing evidence to identify the most valid,reliable,health-related,safe,and feasiblefitness tests to be used in children and adolescents aged 618 years.We designed a single-panel modified Delphi study and invited 216 experts from all around the world to answer this Delphi survey,of whom one-third are from low-to-middle income countries and one-third are women.Four experts were involved in the piloting of the survey and did not participate in the main Delphi study to avoid bias.We pre-defined an agreement of 80%among the expert participants to achieve consensus.Results:We obtained a high response rate(78%)with a total of 169fitness experts from 50 countries and territories,including 63 women and 61 experts from low-or middle-income countries/territories.Consensus(>85%agreement)was achieved for all proposed tests and protocols,supporting the YFIT battery,which includes weight and height(to compute body mass index as a proxy of body size/composition),the 20-m shuttle run(cardiorespiratoryfitness),handgrip strength,and standing long jump(muscularfitness).Conclusion:This study contributes to standardizingfitness tests and protocols used for research,monitoring,and surveillance across the world,which will allow for future data pooling and the development of international and regional sex-and age-specific reference values,health-related cut-points,and a global picture offitness among children and adolescents.展开更多
BACKGROUND Physical activity(PA)is a key contributor to the neurocognitive and psychological development of children and adolescents.With the rapid integration of digital technologies in educational and recreational c...BACKGROUND Physical activity(PA)is a key contributor to the neurocognitive and psychological development of children and adolescents.With the rapid integration of digital technologies in educational and recreational contexts,technology-enhanced PA(TEPA)interventions have emerged as promising tools for promoting mental and cognitive health.However,the effectiveness of various TEPA modalities—such as virtual reality(VR),mobile applications,and biofeedback systems—remains unclear.Prior findings are fragmented across systematic reviews with inconsistent methodologies.This umbrella review was conducted to synthesize current evidence and evaluate whether specific TEPA modalities yield differential benefits.We hypothesized that TEPA interventions with immersive and selfregulatory features provide greater enhancements in executive function(EF),cognitive function(CF),and mental health(MH)than passive or minimally interactive formats.AIM To determine the effects of TEPA interventions and modality-specific characteristics on EF,CF,and MH outcomes in children and adolescents.METHODS An umbrella review of systematic reviews and meta-analyses was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines.Five databases(PubMed,Web of Science,EMBASE,EBSCOhost,and Cochrane Library)were searched up to March 2025.Eligible reviews included participants aged≤18 years,assessed TEPA interventions,and reported EF,CF,or MH outcomes.Methodological quality was assessed using A Measurement Tool to Assess Systematic Reviews 2.Data synthesis was stratified by intervention modality,and heterogeneity was evaluated using the I^(2)statistic.RESULTS A total of 11 systematic reviews and meta-analyses were included.Interventions using VR(2/2),game-based formats(2/2),biofeedback(2/2),and multicomponent programs(1/1)showed consistent evidence of improvements in EF and MH(e.g.,EF:6.92±3.86 vs 3.61±1.67,P<0.001).App-based interventions(3/3)demonstrated mixed or modest effects,while augmented reality-based formats showed limited efficacy.MH outcomes were most frequently improved(9/11 reviews),followed by EF(6/11 reviews)and CF(5/11 reviews).Heterogeneity ranged from moderate to high(I^(2)=42%-78%)across modalities.CONCLUSION TEPA significantly improves MH and selectively enhances executive and CF in youth.Immersive,interactive,and biofeedback-driven modalities are particularly effective.展开更多
This study examines the impact of political polarization on youth engagement in Brazil,focusing on the intersection of historical legacies,cultural dynamics,and modern political influences.Tracing the evolution of pol...This study examines the impact of political polarization on youth engagement in Brazil,focusing on the intersection of historical legacies,cultural dynamics,and modern political influences.Tracing the evolution of polarization from the military dictatorship era to contemporary politics under Jair Bolsonaro,the study explores how polarized rhetoric,misinformation,and digital media have reshaped the political landscape for young Brazilians.Data for the study were collected through a survey of 159 college students aged 18-25 from public and private institutions across Brazil,complemented by 10 interviews with youth activists and party leaders from the Workers’Party(PT)and the Liberal Party(PL).These methods aimed to evaluate how polarization affects young people’s beliefs,political identities,behaviors,engagement levels,and ability to participate in constructive political discourse.The findings reveal that while polarization fosters hostility and deepens ideological divides,it also inspires youth activism by creating a sense of identity and belonging.Education,digital information channels,and the lack of representation in leadership roles emerge as key factors shaping youth engagement.Despite challenges,the research underscores hope:young Brazilians display resilience,critical awareness,and a shared desire for accountability and inclusivity.This study highlights the potential of youth to bridge divides and lead Brazil toward a more collaborative and democratic future.展开更多
The G20 Youth Summit(Y20)took place in Johannesburg,South Africa,from 18 to 23 August.Sun Ruoshui,a research assistant from the Institute of Climate Change and Sustainable Development,Tsinghua University,was appointed...The G20 Youth Summit(Y20)took place in Johannesburg,South Africa,from 18 to 23 August.Sun Ruoshui,a research assistant from the Institute of Climate Change and Sustainable Development,Tsinghua University,was appointed by the All-China Youth Federation to represent China in the discussions on Climate and Environmental Sustainability.Specialising in global climate governance,international climate negotiation and climate policy,Sun has previously served as a member of the Chinese delegation to the 2023 United Nations Climate Change Conference(COP28)and 2024 Bonn Subsidiary Bodies Meeting.展开更多
Objectives:The climate crisis demands urgent action from all sectors of society,including young people in higher education.While previous research has explored individual and contextual predictors of pro-environmental...Objectives:The climate crisis demands urgent action from all sectors of society,including young people in higher education.While previous research has explored individual and contextual predictors of pro-environmental behaviour(PEB),the contribution of Positive Youth Development(PYD)remains underexplored.This study investigates the relationship between PYD dimensions(Competence,Confidence,Connection,Character,and Caring)and two environmental outcomes:environmental habits and climate change awareness,considering gender differences.Methods:A cross-sectional study was conducted with a sample of 1779 students from 10 universities in Andalusia(Spain).Data were collected through an online survey assessing PYD indicators,PEB,and sociodemographic variables.Descriptive statistics,t-tests,correlation analyses,and multiple mediation models were performed.Results:Descriptive analyses indicated moderate levels of PYD dimensions and PEB across the sample.Among the 5 Cs,Caring had a positive association with environmental habits(r 0.22,p 0.001)and climate change awareness(r=<=0.30,p 0.001).Character also had a positive effect on both environmental habits(r 0.23,p 0.001)and climate<=<change awareness(r 0.30,p 0.001).Competence and Confidence were not significantly associated,and Connection=<demonstrated limited predictive value,potentially influenced by contextual or social factors.Gender differences were also identified,with women showing higher scores in Character(d 0.29,p 0.001),Caring(d 0.63,p 0.001),=<=<environmental habits(d 0.20,p 0.001)and climate change awareness(d 0.40,p 0.001),while men scored higher in=<=<Competence(d 0.57,p 0.001)and Confidence(d 0.22,p 0.001).Mediation analyses indicated that the association=<=<between gender and environmental habits was totally explained by Character(β95%CI:and=-0.02;-0.04;-0.01)Caring(β95%CI:Furthermore,the relationship between gender and climate change awareness=-0.04;-0.05,-0.02).was partially mediated by Character(β95%CI:and Caring(β95%CI:=-0.03;-0.05;-0.02)=-0.05;-0.07,-0.03).Conclusions:Females showed more environmental habits and climate change awareness than males,because of their greater scores in both Caring and Character dimensions of PYD.These findings highlight the importance of the PYD for promoting PEB and engaged citizens among young adults.Gender-sensitive and interdisciplinary interventions,such as environmental volunteering and community-based programmes,are recommended for university contexts to enhance sustainable development behaviours and values.展开更多
Background:Youth emerge as an essential period in forming lifelong health and well-being.During adolescence,physical activity(PA)improves cardiovascular health,fitness levels,and the prevention of chronic illnesses,an...Background:Youth emerge as an essential period in forming lifelong health and well-being.During adolescence,physical activity(PA)improves cardiovascular health,fitness levels,and the prevention of chronic illnesses,and the positive effect is also extended to the mental realm,as PA reduces symptoms of anxiety and depression.Therefore,the current study aims to enhance our understanding of the correlation between sports participation and depressive symptoms.Additionally,it seeks to explore how demographics such as gender,age,and race can shape these connections.Methods:The research sample was established by utilising the U.S.Youth Risk Behavior Surveillance(YRBS)2019 cycle,and the eligible samples from this cycle were included in the current study.A self-administered survey evaluated sports participation,categorized as Zero,one,two,three,or more teams.This study included 16,104 participants and conducted self-reported questionnaires on gender,grade,race/ethnicity,and depressive symptoms.The study had a nationally representative population of American students in Grades 10 to 12(aged 14–17 years).Results:A total of 7843 females and 8261 males,distributed across age groups(14 years old,15 years old,16 years old,and 17 years old),with the numbers 3430,4445,4300,and 3929,respectively.Overall,there was a negative correlation between sports participation and feelings of sadness(a symptom of depression)among the subjects.This significant relationship between participating in sports teams and experiencing sadness was dose dependent.Conclusion:Youth with more team sports participation is likely to display lower depression symptoms,and differences in demographic factors such as gender,race,and age are detected.Physical activity research is responsible for attending to social equity issues and fostering inclusiveness,particularly concerning different gender and ethnic groups.展开更多
This study in Gadarif State,Sudan,analyzes the crucial role of youth in conflict resolution and peace building efforts amidst the ongoing crisis.Findings reveal that youth,facing economic,environmental,and security ch...This study in Gadarif State,Sudan,analyzes the crucial role of youth in conflict resolution and peace building efforts amidst the ongoing crisis.Findings reveal that youth,facing economic,environmental,and security challenges,actively engage in peacemaking through initiatives,emergency rooms,and cultural programs,contributing to social cohesion and combatting hate speech.Despite their willingness to build peace,they encounter obstacles like the lack of training programs,limited support,and marginalization in policy-making processes.Recommendations emphasize the necessity of empowering youth through training programs,enhancing government support,and addressing negative perceptions from older generations towards youth contributions.Conclusively,prioritizing youth issues and fostering their participation in peace building initiatives are essential for sustainable peace and social harmony in Gadarif State.展开更多
Bipolar disorder is a highly heritable and functionally impairing disease.The recognition and intervention of BD especially that characterized by early onset remains challenging.Risk biomarkers for predicting BD trans...Bipolar disorder is a highly heritable and functionally impairing disease.The recognition and intervention of BD especially that characterized by early onset remains challenging.Risk biomarkers for predicting BD transition among at-risk youth may improve disease prognosis.We reviewed the more recent clinical studies to find possible pre-diagnostic biomarkers in youth at familial or(and)clinical risk of BD.Here we found that putative biomarkers for predicting conversion to BD include findings from multiple sample sources based on different hypotheses.Putative risk biomarkers shown by perspective studies are higher bipolar polygenetic risk scores,epigenetic alterations,elevated immune parameters,front-limbic system deficits,and brain circuit dysfunction associated with emotion and reward processing.Future studies need to enhance machine learning integration,make clinical detection methods more objective,and improve the quality of cohort studies.展开更多
Background:Given the heightened risk of developmental challenges associated with preterm birth,it is crucial to explore interventions that may ameliorate potential adverse outcomes.This study aimed to examine whether ...Background:Given the heightened risk of developmental challenges associated with preterm birth,it is crucial to explore interventions that may ameliorate potential adverse outcomes.This study aimed to examine whether meeting the 24-h movement behavior(24-HMB)guidelines,which include recommendations on physical activity(PA),screen time(ST),and sleep(SL),is related to indicators of cognitive difficulties,internalizing problems(e.g.,depression and anxiety),and externalizing problems(e.g.,difficulties in making friends and arguing)in a sample of preterm youth(children and adolescents born preterm).Methods:In this cross-sectional study,data from 3410 preterm youth(aged 6 to 17 years)were included for data analyses.Multivariable logistic regression was used to investigate associations between meeting the 24-HMB guidelines and the above-mentioned health outcomes,while controlling for sociodemographic and health-related factors.Results:The prevalence of meeting 24-HMB guidelines varied across independent and integrated components of the 24-HMB guidelines.Meeting the ST guideline alone(p<0.05)and integrated guidelines(i.e.,ST+SL and ST+SL+PA)were associated with fewer cognitive difficulties and reduced internalizing and externalizing problems(p<0.05).Specifically,meeting the SL guideline alone and integrated guidelines(i.e.,SL+ST)were associated with lower odds of depression and anxiety(p<0.01).Additionally,meeting independent,and integrated(PA and/or ST)guidelines were associated with less pronounced difficulties in making friends and arguing(p<0.05).Meeting 24-HMB guidelines in an isolated and integrated manner are linked to better cognitive performance and fewer internalizing and externalizing problems in preterm youth.Conclusion:Results suggest that advocating for the implementation of the 24-HMB guidelines may reduce cognitive challenges and behavioral issues,which is of high relevance for improving public health.Future longitudinal studies in preterm youth should investigate how modifying specific 24-HMB behaviors,especially ST,influence cognitive difficulties,internalizing and externalizing problems in this vulnerable population.展开更多
Background: Access to safe and effective contraception is crucial for sexual and reproductive health to be at its best. This allows improved pregnancy results and the avoidance of unintended births. Teenagers’ views ...Background: Access to safe and effective contraception is crucial for sexual and reproductive health to be at its best. This allows improved pregnancy results and the avoidance of unintended births. Teenagers’ views on using contraceptives are influenced by the information available at their disposal. The study assessed the influential factors affecting the utilization of modern contraceptives among the youth in Akuse in the Eastern Region of Ghana. Methods: The data for the study were gathered from 378 consented youth aged 15 - 24 years using a quantitative cross-sectional study design and a well-structured questionnaire. Person’s Chi-Square test was adopted to measure the association between the outcome variable and selected independent variables. Logistic regression models were utilized to measure the odds of the factors influencing modern contraceptive use among the respondents. Results: The results of the study suggested a high knowledge level of contraceptives;however, the prevalence of utilization was low. The level of education and age were factors found to influence the uptake of contraceptives. A bivariate analysis to examine the association between selected socio-demographic variables revealed that educational level (p = 0.044), religious affiliation (p = 0.002), and ethnicity (p = 0.016) were statistically associated with modern contraceptive use among the respondents. All other tested demographic variables including the age groups, gender, marital status, and residential status proved otherwise at the observed p-values greater than the 0.05 threshold. Respondents who indicated staying with partners were 6.79 times more likely to use contraceptives compared to their counterparts staying with a parent, after controlling for all other covariates. Conclusions: Based on the findings of this study, it was concluded that high contraceptive knowledge influences the choice of contraceptive preferred by the youth, and contraceptive use is also influenced by the advancement in age and educational level of the youth. It is however recommended that parents, guidance, and teachers be entreated to offer relevant and timely sexual information or education as these will most likely improve the uptake of modern contraceptives among the targeted population.展开更多
‘Selfie’taking was introduced to the common people by smartphones and has become a common practice across the globe in no time.With technological advancement and the popularity of smartphones,selfie-taking has grown...‘Selfie’taking was introduced to the common people by smartphones and has become a common practice across the globe in no time.With technological advancement and the popularity of smartphones,selfie-taking has grown rapidly within a short time.In light of the new trend set by the generation,this study aimed to explore reasons for selfie-taking and selfie-posting on social media and their effects on the social and psychological lives of young adults.A purposive sampling method was adopted to select 20 Indian citizens,between 18 and 24 years.The data were collected through semi-structured interviews and analysed using thematic analysis.Selfie-taking and posting on social media give positive feelings,and it acts as a mood modifier dependent mostly on the favourability and feedback about the post which in turn affects emotions and self-satisfaction.展开更多
The rising of aging and the declining of birth rates have forced the public to focus on the youth’s view on marriage.Based on critical discourse analysis and combined with Fairclough’s three-dimensional discourse an...The rising of aging and the declining of birth rates have forced the public to focus on the youth’s view on marriage.Based on critical discourse analysis and combined with Fairclough’s three-dimensional discourse analysis model,this paper builds a“Chinese media News Report Corpus on the topic of‘marriage’”whose news are collected from China Daily.It is found that the discourses are neutral and objective with regard to the advantages and disadvantages of marriage,but in general,it is still a traditional view of marriage that is inevitable and closely related to fertility.Although this is controlled by the policies and the social reasons including declining fertility rate,it deviates from the current view of the youth towards marriage,resulting in many serious consequences such as young people’s rejection.In addition,this research found that male and female have great differences in their views on marriage,and men’s resistance to marriage is far greater than that of women,which is departure from the public’s cognition.The reasons behind this need to be explored in order to solve the marriage and love problems of young people in today’s era and realize the healthy development of young marriage.展开更多
文摘From June 4 to 17,2025,the Harmony Together for a Friendly Future-Exhibition of Intermitioncil Youth Photography,jointly hosted by China Center of International Cultural Exchange and Tourism Promotion(CETP)nnd China Cultural Center in Copenhagen,was successfully held at the China Cultured Center in Copenhagen.
文摘The ITU Global Youth Celebration(GYC-25)is more than just a celebration.It reaffirms our commitment to youth as essential partners in building a connected,inclusive,and sustainable digital future.This is where bold ideas meet real action.Get ready for an electrifying mix of inspiration,learning,and co-creation all fueled by youth leadership and digital innovation.
文摘Youth representatives from 13 countries gathered in Jinshan Peach Orchard,where a local farmer introduced them to the centuriesold history of flat peach cultivation.Through their lenses,they documented a fusion of traditional wisdom and modern agricultural technology-a living narrative of agricultural progress that connects the past to the present.
文摘On April 19th,"the Youth Table Tennis Programme—Photo Exhibition of Zhou Enlai and the Bandung Conference&China-ASEAN(Indonesia)Youth Table Tennis Training Camp"opened in Jakarta,Indonesia.The event was guided by the Chinese Embassy in Indonesia and co-organised by the ASEAN-China Centre(ACC),the Memorial to Zhou Enlai and Deng Yingchao,the China Friendship Foundation for Peace and Development,the Beijing One Heart Sphere Charity Foundation,and the Enlai Foundation.
基金supported by the Ministry of Science and Technology of China(2020YFA0908900)National Natural Science Foundation of China(21935011 and 82072490)+1 种基金Shenzhen Science and Technology Innovation Commission(KQTD20200820113012029 and KJZD20230923114612025)Guangdong Provincial Key Laboratory of Advanced Biomaterials(2022B1212010003).
文摘Aging is a pivotal risk factor for intervertebral disc degeneration(IVDD)and chronic low back pain(LBP).The restoration of aging nucleus pulposus cells(NPCs)to a youthful epigenetic state is crucial for IVDD treatment,but remains a formidable challenge.Here,we proposed a strategy to partially reprogram and reinstate youthful epigenetics of senescent NPCs by delivering a plasmid carrier that expressed pluripotency-associated genes(Oct4,Klf4 and Sox2)in Cavin2-modified exosomes(OKS@M-Exo)for treatment of IVDD and alleviating LBP.The functional OKS@M-Exo efficaciously alleviated senescence markers(p16^(INK4a),p21^(CIP1)and p53),reduced DNA damage and H4K20me3 expression,as well as restored proliferation ability and metabolic balance in senescent NPCs,as validated through in vitro experiments.In a rat model of IVDD,OKS@M-Exo maintained intervertebral disc height,nucleus pulposus hydration and tissue structure,effectively ameliorated IVDD via decreasing the senescence markers.Additionally,OKS@MExo reduced nociceptive behavior and downregulated nociception markers,indicating its efficiency in alleviating LBP.The transcriptome sequencing analysis also demonstrated that OKS@M-Exo could decrease the expression of age-related pathways and restore cell proliferation.Collectively,reprogramming by the OKS@M-Exo to restore youthful epigenetics of senescent NPCs may hold promise as a therapeutic platform to treat IVDD.
文摘On the evening of May 30th,the parallel forum"Youth Power in Dialogue among Civilisations,"as part of the 4th Dialogue on Exchanges and Mutual Learning among Civilisations,was held in Dunhuang.The forum was hosted by the Chinese Association for International Understanding and organised by the Schwarzman College of Tsinghua University.More than 30 youth representatives from the Schwarzman Scholars international delegation and a delegation of European,American and African NGO friends came together under the theme"The Youth Power of Cross-Civilisation Dialogue.Discussions focused on topics such as cultural inheritance and innovation,and cross-cultural collaboration.The sessions were co-chaired by Professor Pan Qingzhong,Executive Dean of the Schwarzman College,and Joshua Woodard,a Schwarzman Scholar from the United States of America.
文摘This article has been compiled and edited by China Report ASEAN based on an interview with the FAO Office of Youth and Women.As the Food and Agriculture Organization of the United Nations(FAO)celebrates its 80th anniversary,the spotlight is shifting from solely honouring its longstanding mission to also highlighting the dynamic participation of youth and women in driving positive changes in agrifood systems.
文摘From June 4 to 17,2025.the Harmony Together for Friendly future-Exhibition of International Youth Photography.jointly Hosted by China Center for International Culture and Tourism Exchanges(CCICTE) and China Cultural Center in Copenhagen.
基金supported by the Grant PID2020-120249RB-I00PID2023-148404OB-100funded by MCIN/AEI/10.13039/501100011033+4 种基金by the Andalusian Government(Junta de Andalucía,Plan Andaluz de Investigación,ref.P20_00124)by the Erasmus+Sport Programme of the European Union within the project FitBack4Literacy(No.101089829)Additional support is provided by the University of Granada,Plan Propio de Inves-tigación,Units of ExcellenceUnit of Excellence on Exercise,Nutrition and Health(UCEENS)by theCIBERobn Physiopa-thology of Obesity and Nutrition,and by the Spanish Network in Exercise and Health,EXERNET Network(RED2022-134800-Tand EXP_99828).
文摘Background:Physicalfitness in childhood and adolescence is associated with a variety of health outcomes and is a powerful marker of current and future health.However,inconsistencies in tests and protocols limit international monitoring and surveillance.The objective of the study was to seek international consensus on a proposed,evidence-informed,Youth Fitness International Test(YFIT)battery and protocols for health monitoring and surveillance in children and adolescents aged 618 years.Methods:We conducted an international modified Delphi study to evaluate the level of agreement with a proposed,evidence-based,YFIT of core health-relatedfitness tests and protocols to be used worldwide in 6-to 18-year-olds.This proposal was based on previous European and North American projects that systematically reviewed the existing evidence to identify the most valid,reliable,health-related,safe,and feasiblefitness tests to be used in children and adolescents aged 618 years.We designed a single-panel modified Delphi study and invited 216 experts from all around the world to answer this Delphi survey,of whom one-third are from low-to-middle income countries and one-third are women.Four experts were involved in the piloting of the survey and did not participate in the main Delphi study to avoid bias.We pre-defined an agreement of 80%among the expert participants to achieve consensus.Results:We obtained a high response rate(78%)with a total of 169fitness experts from 50 countries and territories,including 63 women and 61 experts from low-or middle-income countries/territories.Consensus(>85%agreement)was achieved for all proposed tests and protocols,supporting the YFIT battery,which includes weight and height(to compute body mass index as a proxy of body size/composition),the 20-m shuttle run(cardiorespiratoryfitness),handgrip strength,and standing long jump(muscularfitness).Conclusion:This study contributes to standardizingfitness tests and protocols used for research,monitoring,and surveillance across the world,which will allow for future data pooling and the development of international and regional sex-and age-specific reference values,health-related cut-points,and a global picture offitness among children and adolescents.
基金Supported by the 2025 Undergraduate Research Project of the Shandong Society for Innovation and Development in Philosophy and Social Sciences,No.Z-DXS25007。
文摘BACKGROUND Physical activity(PA)is a key contributor to the neurocognitive and psychological development of children and adolescents.With the rapid integration of digital technologies in educational and recreational contexts,technology-enhanced PA(TEPA)interventions have emerged as promising tools for promoting mental and cognitive health.However,the effectiveness of various TEPA modalities—such as virtual reality(VR),mobile applications,and biofeedback systems—remains unclear.Prior findings are fragmented across systematic reviews with inconsistent methodologies.This umbrella review was conducted to synthesize current evidence and evaluate whether specific TEPA modalities yield differential benefits.We hypothesized that TEPA interventions with immersive and selfregulatory features provide greater enhancements in executive function(EF),cognitive function(CF),and mental health(MH)than passive or minimally interactive formats.AIM To determine the effects of TEPA interventions and modality-specific characteristics on EF,CF,and MH outcomes in children and adolescents.METHODS An umbrella review of systematic reviews and meta-analyses was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines.Five databases(PubMed,Web of Science,EMBASE,EBSCOhost,and Cochrane Library)were searched up to March 2025.Eligible reviews included participants aged≤18 years,assessed TEPA interventions,and reported EF,CF,or MH outcomes.Methodological quality was assessed using A Measurement Tool to Assess Systematic Reviews 2.Data synthesis was stratified by intervention modality,and heterogeneity was evaluated using the I^(2)statistic.RESULTS A total of 11 systematic reviews and meta-analyses were included.Interventions using VR(2/2),game-based formats(2/2),biofeedback(2/2),and multicomponent programs(1/1)showed consistent evidence of improvements in EF and MH(e.g.,EF:6.92±3.86 vs 3.61±1.67,P<0.001).App-based interventions(3/3)demonstrated mixed or modest effects,while augmented reality-based formats showed limited efficacy.MH outcomes were most frequently improved(9/11 reviews),followed by EF(6/11 reviews)and CF(5/11 reviews).Heterogeneity ranged from moderate to high(I^(2)=42%-78%)across modalities.CONCLUSION TEPA significantly improves MH and selectively enhances executive and CF in youth.Immersive,interactive,and biofeedback-driven modalities are particularly effective.
文摘This study examines the impact of political polarization on youth engagement in Brazil,focusing on the intersection of historical legacies,cultural dynamics,and modern political influences.Tracing the evolution of polarization from the military dictatorship era to contemporary politics under Jair Bolsonaro,the study explores how polarized rhetoric,misinformation,and digital media have reshaped the political landscape for young Brazilians.Data for the study were collected through a survey of 159 college students aged 18-25 from public and private institutions across Brazil,complemented by 10 interviews with youth activists and party leaders from the Workers’Party(PT)and the Liberal Party(PL).These methods aimed to evaluate how polarization affects young people’s beliefs,political identities,behaviors,engagement levels,and ability to participate in constructive political discourse.The findings reveal that while polarization fosters hostility and deepens ideological divides,it also inspires youth activism by creating a sense of identity and belonging.Education,digital information channels,and the lack of representation in leadership roles emerge as key factors shaping youth engagement.Despite challenges,the research underscores hope:young Brazilians display resilience,critical awareness,and a shared desire for accountability and inclusivity.This study highlights the potential of youth to bridge divides and lead Brazil toward a more collaborative and democratic future.
文摘The G20 Youth Summit(Y20)took place in Johannesburg,South Africa,from 18 to 23 August.Sun Ruoshui,a research assistant from the Institute of Climate Change and Sustainable Development,Tsinghua University,was appointed by the All-China Youth Federation to represent China in the discussions on Climate and Environmental Sustainability.Specialising in global climate governance,international climate negotiation and climate policy,Sun has previously served as a member of the Chinese delegation to the 2023 United Nations Climate Change Conference(COP28)and 2024 Bonn Subsidiary Bodies Meeting.
文摘Objectives:The climate crisis demands urgent action from all sectors of society,including young people in higher education.While previous research has explored individual and contextual predictors of pro-environmental behaviour(PEB),the contribution of Positive Youth Development(PYD)remains underexplored.This study investigates the relationship between PYD dimensions(Competence,Confidence,Connection,Character,and Caring)and two environmental outcomes:environmental habits and climate change awareness,considering gender differences.Methods:A cross-sectional study was conducted with a sample of 1779 students from 10 universities in Andalusia(Spain).Data were collected through an online survey assessing PYD indicators,PEB,and sociodemographic variables.Descriptive statistics,t-tests,correlation analyses,and multiple mediation models were performed.Results:Descriptive analyses indicated moderate levels of PYD dimensions and PEB across the sample.Among the 5 Cs,Caring had a positive association with environmental habits(r 0.22,p 0.001)and climate change awareness(r=<=0.30,p 0.001).Character also had a positive effect on both environmental habits(r 0.23,p 0.001)and climate<=<change awareness(r 0.30,p 0.001).Competence and Confidence were not significantly associated,and Connection=<demonstrated limited predictive value,potentially influenced by contextual or social factors.Gender differences were also identified,with women showing higher scores in Character(d 0.29,p 0.001),Caring(d 0.63,p 0.001),=<=<environmental habits(d 0.20,p 0.001)and climate change awareness(d 0.40,p 0.001),while men scored higher in=<=<Competence(d 0.57,p 0.001)and Confidence(d 0.22,p 0.001).Mediation analyses indicated that the association=<=<between gender and environmental habits was totally explained by Character(β95%CI:and=-0.02;-0.04;-0.01)Caring(β95%CI:Furthermore,the relationship between gender and climate change awareness=-0.04;-0.05,-0.02).was partially mediated by Character(β95%CI:and Caring(β95%CI:=-0.03;-0.05;-0.02)=-0.05;-0.07,-0.03).Conclusions:Females showed more environmental habits and climate change awareness than males,because of their greater scores in both Caring and Character dimensions of PYD.These findings highlight the importance of the PYD for promoting PEB and engaged citizens among young adults.Gender-sensitive and interdisciplinary interventions,such as environmental volunteering and community-based programmes,are recommended for university contexts to enhance sustainable development behaviours and values.
基金supported by the Reform and Innovation of Physical Education Courses in General Education Modules of Science and Technology Universities under the Background of Discipline Integration(No.2024YBJG082)the Practice of Physical Education Curriculum Reform in Sino-Foreign Cooperative Schools in the Guangdong-Hong Kong-Macao Greater Bay Area:A Case Study of the Hong Kong University of Science and Technology(Guangzhou)(No.2024110425).
文摘Background:Youth emerge as an essential period in forming lifelong health and well-being.During adolescence,physical activity(PA)improves cardiovascular health,fitness levels,and the prevention of chronic illnesses,and the positive effect is also extended to the mental realm,as PA reduces symptoms of anxiety and depression.Therefore,the current study aims to enhance our understanding of the correlation between sports participation and depressive symptoms.Additionally,it seeks to explore how demographics such as gender,age,and race can shape these connections.Methods:The research sample was established by utilising the U.S.Youth Risk Behavior Surveillance(YRBS)2019 cycle,and the eligible samples from this cycle were included in the current study.A self-administered survey evaluated sports participation,categorized as Zero,one,two,three,or more teams.This study included 16,104 participants and conducted self-reported questionnaires on gender,grade,race/ethnicity,and depressive symptoms.The study had a nationally representative population of American students in Grades 10 to 12(aged 14–17 years).Results:A total of 7843 females and 8261 males,distributed across age groups(14 years old,15 years old,16 years old,and 17 years old),with the numbers 3430,4445,4300,and 3929,respectively.Overall,there was a negative correlation between sports participation and feelings of sadness(a symptom of depression)among the subjects.This significant relationship between participating in sports teams and experiencing sadness was dose dependent.Conclusion:Youth with more team sports participation is likely to display lower depression symptoms,and differences in demographic factors such as gender,race,and age are detected.Physical activity research is responsible for attending to social equity issues and fostering inclusiveness,particularly concerning different gender and ethnic groups.
基金Our sincere thanks to the European Union of the project teams of Enabling University Peace Education in British Council and all those who provided unconditional support.We would like to thank Dr.Muatsim Ibrahim Malik as supervisor and Dr.Afag Mohammed Sadig as co-supervisor for their support,suggestions and comments that helped us improve the same.We are also grateful to Ustaz Bashir Ibrahim for his help and support in data collection.A special mention and grateful thanks to Gadarif community specifically youth for their cooperation in data collection,which has contributed to our research experience.
文摘This study in Gadarif State,Sudan,analyzes the crucial role of youth in conflict resolution and peace building efforts amidst the ongoing crisis.Findings reveal that youth,facing economic,environmental,and security challenges,actively engage in peacemaking through initiatives,emergency rooms,and cultural programs,contributing to social cohesion and combatting hate speech.Despite their willingness to build peace,they encounter obstacles like the lack of training programs,limited support,and marginalization in policy-making processes.Recommendations emphasize the necessity of empowering youth through training programs,enhancing government support,and addressing negative perceptions from older generations towards youth contributions.Conclusively,prioritizing youth issues and fostering their participation in peace building initiatives are essential for sustainable peace and social harmony in Gadarif State.
基金supported by the Beijing Commission of Science and Technology (Z191100006619113)the National Natural Science Foundation of China (32070589 and 82171500).
文摘Bipolar disorder is a highly heritable and functionally impairing disease.The recognition and intervention of BD especially that characterized by early onset remains challenging.Risk biomarkers for predicting BD transition among at-risk youth may improve disease prognosis.We reviewed the more recent clinical studies to find possible pre-diagnostic biomarkers in youth at familial or(and)clinical risk of BD.Here we found that putative biomarkers for predicting conversion to BD include findings from multiple sample sources based on different hypotheses.Putative risk biomarkers shown by perspective studies are higher bipolar polygenetic risk scores,epigenetic alterations,elevated immune parameters,front-limbic system deficits,and brain circuit dysfunction associated with emotion and reward processing.Future studies need to enhance machine learning integration,make clinical detection methods more objective,and improve the quality of cohort studies.
基金supported by the Shenzhen Educational Research Funding(Grant No.zdzb2014)the Shenzhen Science and Technology Innovation Commission(Grant No.202307313000096)+3 种基金the Social Science Foundation from China’s Ministry of Education(Grant No.23YJA880093)a Post-Doctoral Fellowship(Grant No.2022M711174)the National Center for Mental Health(Grant No.Z014)a Research Excellence Scholarship of Shenzhen University(Grant No.ZYZD2305).
文摘Background:Given the heightened risk of developmental challenges associated with preterm birth,it is crucial to explore interventions that may ameliorate potential adverse outcomes.This study aimed to examine whether meeting the 24-h movement behavior(24-HMB)guidelines,which include recommendations on physical activity(PA),screen time(ST),and sleep(SL),is related to indicators of cognitive difficulties,internalizing problems(e.g.,depression and anxiety),and externalizing problems(e.g.,difficulties in making friends and arguing)in a sample of preterm youth(children and adolescents born preterm).Methods:In this cross-sectional study,data from 3410 preterm youth(aged 6 to 17 years)were included for data analyses.Multivariable logistic regression was used to investigate associations between meeting the 24-HMB guidelines and the above-mentioned health outcomes,while controlling for sociodemographic and health-related factors.Results:The prevalence of meeting 24-HMB guidelines varied across independent and integrated components of the 24-HMB guidelines.Meeting the ST guideline alone(p<0.05)and integrated guidelines(i.e.,ST+SL and ST+SL+PA)were associated with fewer cognitive difficulties and reduced internalizing and externalizing problems(p<0.05).Specifically,meeting the SL guideline alone and integrated guidelines(i.e.,SL+ST)were associated with lower odds of depression and anxiety(p<0.01).Additionally,meeting independent,and integrated(PA and/or ST)guidelines were associated with less pronounced difficulties in making friends and arguing(p<0.05).Meeting 24-HMB guidelines in an isolated and integrated manner are linked to better cognitive performance and fewer internalizing and externalizing problems in preterm youth.Conclusion:Results suggest that advocating for the implementation of the 24-HMB guidelines may reduce cognitive challenges and behavioral issues,which is of high relevance for improving public health.Future longitudinal studies in preterm youth should investigate how modifying specific 24-HMB behaviors,especially ST,influence cognitive difficulties,internalizing and externalizing problems in this vulnerable population.
文摘Background: Access to safe and effective contraception is crucial for sexual and reproductive health to be at its best. This allows improved pregnancy results and the avoidance of unintended births. Teenagers’ views on using contraceptives are influenced by the information available at their disposal. The study assessed the influential factors affecting the utilization of modern contraceptives among the youth in Akuse in the Eastern Region of Ghana. Methods: The data for the study were gathered from 378 consented youth aged 15 - 24 years using a quantitative cross-sectional study design and a well-structured questionnaire. Person’s Chi-Square test was adopted to measure the association between the outcome variable and selected independent variables. Logistic regression models were utilized to measure the odds of the factors influencing modern contraceptive use among the respondents. Results: The results of the study suggested a high knowledge level of contraceptives;however, the prevalence of utilization was low. The level of education and age were factors found to influence the uptake of contraceptives. A bivariate analysis to examine the association between selected socio-demographic variables revealed that educational level (p = 0.044), religious affiliation (p = 0.002), and ethnicity (p = 0.016) were statistically associated with modern contraceptive use among the respondents. All other tested demographic variables including the age groups, gender, marital status, and residential status proved otherwise at the observed p-values greater than the 0.05 threshold. Respondents who indicated staying with partners were 6.79 times more likely to use contraceptives compared to their counterparts staying with a parent, after controlling for all other covariates. Conclusions: Based on the findings of this study, it was concluded that high contraceptive knowledge influences the choice of contraceptive preferred by the youth, and contraceptive use is also influenced by the advancement in age and educational level of the youth. It is however recommended that parents, guidance, and teachers be entreated to offer relevant and timely sexual information or education as these will most likely improve the uptake of modern contraceptives among the targeted population.
文摘‘Selfie’taking was introduced to the common people by smartphones and has become a common practice across the globe in no time.With technological advancement and the popularity of smartphones,selfie-taking has grown rapidly within a short time.In light of the new trend set by the generation,this study aimed to explore reasons for selfie-taking and selfie-posting on social media and their effects on the social and psychological lives of young adults.A purposive sampling method was adopted to select 20 Indian citizens,between 18 and 24 years.The data were collected through semi-structured interviews and analysed using thematic analysis.Selfie-taking and posting on social media give positive feelings,and it acts as a mood modifier dependent mostly on the favourability and feedback about the post which in turn affects emotions and self-satisfaction.
文摘The rising of aging and the declining of birth rates have forced the public to focus on the youth’s view on marriage.Based on critical discourse analysis and combined with Fairclough’s three-dimensional discourse analysis model,this paper builds a“Chinese media News Report Corpus on the topic of‘marriage’”whose news are collected from China Daily.It is found that the discourses are neutral and objective with regard to the advantages and disadvantages of marriage,but in general,it is still a traditional view of marriage that is inevitable and closely related to fertility.Although this is controlled by the policies and the social reasons including declining fertility rate,it deviates from the current view of the youth towards marriage,resulting in many serious consequences such as young people’s rejection.In addition,this research found that male and female have great differences in their views on marriage,and men’s resistance to marriage is far greater than that of women,which is departure from the public’s cognition.The reasons behind this need to be explored in order to solve the marriage and love problems of young people in today’s era and realize the healthy development of young marriage.
