Lactiplantibacillus plantarum Y42 exhibited good bioactivity in our previous study.In this study,the whole genome of L.plantarum Y42 was sequenced and its genome sequence information and function were analyzed to inve...Lactiplantibacillus plantarum Y42 exhibited good bioactivity in our previous study.In this study,the whole genome of L.plantarum Y42 was sequenced and its genome sequence information and function were analyzed to investigate its genotype and possible probiotic qualities.Thegenome of L.plantarum Y42 consisted of a circular 3.32 M bp chromosome,1 linear plasmid(0.013 M bp)and 1 ring-shaped plasmid(0.054 M bp),and contained a variety of genes associated with beneficial functions such as bacterial adhesion,acid tolerance,bile salt tolerance and heat tolerance.In particular,five genes associated with quorum sensing(QS)system(LuxS,Pfs,agrA,agrB,ftsH),three complete extracellular polysaccharide(EPS)synthesis gene clusters(cps2,cps3,cps4)and a cluster of pln genes encoding bacteriocins,which contains 21 genes,were identified in the L.plantarum Y42 genome.These results reveal the potential probiotic mechanism of L.plantarum Y42 at the gene level,and theoretically underlie its probiotic function excavation and practical application.展开更多
基金supported by the National Natural Science Foundation of China(32072193).
文摘Lactiplantibacillus plantarum Y42 exhibited good bioactivity in our previous study.In this study,the whole genome of L.plantarum Y42 was sequenced and its genome sequence information and function were analyzed to investigate its genotype and possible probiotic qualities.Thegenome of L.plantarum Y42 consisted of a circular 3.32 M bp chromosome,1 linear plasmid(0.013 M bp)and 1 ring-shaped plasmid(0.054 M bp),and contained a variety of genes associated with beneficial functions such as bacterial adhesion,acid tolerance,bile salt tolerance and heat tolerance.In particular,five genes associated with quorum sensing(QS)system(LuxS,Pfs,agrA,agrB,ftsH),three complete extracellular polysaccharide(EPS)synthesis gene clusters(cps2,cps3,cps4)and a cluster of pln genes encoding bacteriocins,which contains 21 genes,were identified in the L.plantarum Y42 genome.These results reveal the potential probiotic mechanism of L.plantarum Y42 at the gene level,and theoretically underlie its probiotic function excavation and practical application.
