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Transcriptomic profiling of cardiac development in Bama Xiang pigs across key developmental stages
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作者 Sheng-Nan Wang Wen-Jie Tian +4 位作者 Deng-Ke Pan Tang Hai Yue-Hui Ma Dan-Dan Wang Lin Jiang 《Zoological Research》 2025年第3期634-646,共13页
Pigs have emerged as valuable large-animal models for cardiac xenotransplantation;however,the temporal dynamics of myocardial development in this species remains insufficiently defined.This study analyzed gene express... Pigs have emerged as valuable large-animal models for cardiac xenotransplantation;however,the temporal dynamics of myocardial development in this species remains insufficiently defined.This study analyzed gene expression patterns across four key developmental stages(neonatal,juvenile,sexual maturity,and adulthood)to delineate the molecular mechanisms driving porcine myocardial development.Increases in heart weight were accompanied by proportional expansion of myocardial fiber area and chamber size,reflecting coordinated structural development.Transcriptomic profiling of myocardial tissue by RNA sequencing(RNA-seq)identified 2189 differentially expressed genes(DEGs)across stage comparisons.Short time-series expression miner(STEM)analysis classified these DEGs into four major expression clusters enriched in pathways associated with myocardial development,immune responses,cell proliferation,and metabolic processes.Among 359 DEGs conserved across all developmental stages,six candidate genes were strongly associated with myocardial development.Reverse transcription-quantitative real-time polymerase chain reaction(RT-qPCR)confirmed a significant correlation between the expression of these candidate genes and myocardial development in porcine tissue.These findings establish a transcriptomic framework for porcine myocardial maturation and provide a molecular basis for advancing cardiac xenotransplantation. 展开更多
关键词 Cardiac tissue Bama xiang pig Multiple stages Heart development TRANSCRIPTOMICS
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Using Xiang Thinking to Unravel the Mystery of Wu Xing in Traditional Chinese Medicine
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作者 LIU Qian 《Chinese Medicine and Culture》 2025年第1期24-31,共8页
From the perspective of Xiang thinking(象思维imagery thinking),the application of Wu Xing(五行five elements)in traditional Chinese medicine(TCM)provides a reasonable cognitive model.Wu Xing with the earth in the cent... From the perspective of Xiang thinking(象思维imagery thinking),the application of Wu Xing(五行five elements)in traditional Chinese medicine(TCM)provides a reasonable cognitive model.Wu Xing with the earth in the center(中土五行)helps TCM establish extensive connections between the human body and the universe,while Wu Xing in the generating and conquering cycles(生克五行)incorporates everything into a systematic thinking framework through complex dialectical relationships,becoming an ideal cognitive tool for TCM diagnosis and treatment.In essence,Wu Xing represents an upgrade of yin-yang dialectical thinking into a two-dimensional Xiang thinking diagram,possessing powerful explanatory capabilities.When faced with complex life systems,Wu Xing provides TCM with a theoretical framework,and TCM,in turn,offers a practical application for Wu Xing. 展开更多
关键词 YIN-YANG Wu Xing(五行) xiang thinking(象思维) Two-dimensional yin-yang structure
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Zang Xiang and Organs:The Encounter of Chinese and Western Medicine and Its Impact of the Connotation of Wu Zang
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作者 LIANG Qiuyu ZHOU Linqi HUANG Zusheng 《Chinese Medicine and Culture》 2025年第3期293-304,共12页
In the context of Western medicine,Xin(心heart),Gan(肝liver),Pi(脾spleen),Fei(肺lung),and Shen(肾kidney)are five specific organs,while in ancient Chinese medicine,they are five kinds of Zang Xiang(藏象visceral manifes... In the context of Western medicine,Xin(心heart),Gan(肝liver),Pi(脾spleen),Fei(肺lung),and Shen(肾kidney)are five specific organs,while in ancient Chinese medicine,they are five kinds of Zang Xiang(藏象visceral manifestation),often referred to as Wu Zang(五藏five zang-organs),representing five interrelated structural-functional systems.There are both differences and connections between visceral manifestations and organs,which are reflected in the theories of Wu Zang.The specific connotation of Wu Zang are determined by the specific context in which they are located.With the accumulation of practice,the Wu Zang of the human body structures and functions,as well as the relationship between the Wu Zang have been in constant development and change.The encounter of Chinese and Western medicine in the 19th century dramatically changed the connotation of Wu Zang,from emphasizing visceral manifestations and neglecting substance to an organs-oriented perspective.This article examines how the encounter of Chinese and Western medicine in China influenced Chinese medicine.By analyzing three key aspects:(1)the interpretation of Wu Zang in pre-16th century texts;(2)the evolution and dissemination of Western medicine during the Ming and Qing dynasties;(3)the shifting conceptualization of Wu Zang in late Qing medical literature—the study elucidates the transformative impact of this cross-cultural medical encounter on the theory and practice of Chinese medicine. 展开更多
关键词 Wu Zang(五脏five zang-organs) Zang xiang(藏象visceral manifestations) ORGANS Encounter of Chinese and Western medicine Culture translation
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Two Female Characters of Tragic Fate from Different Countries—Tess and Xianglin's Wife
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作者 张振虹 冉彩荣 《海外英语》 2014年第24期203-204,281,共3页
This article mainly deals with the comparison between the main character Xiang Lin’s wife in Lu Xun’s short narrative story Blessing and the main character Tess in the novel Tess of the D'Urbervilles written by ... This article mainly deals with the comparison between the main character Xiang Lin’s wife in Lu Xun’s short narrative story Blessing and the main character Tess in the novel Tess of the D'Urbervilles written by the famous critic realistic British writer Hardy in 19th century.This article discusses about the similarities and differences between the two tragic figures from three aspects,namely the background of their times;the origins of their tragedies and the personalities of the two women,so that the readers may have a better understanding of the themes of the two novels. 展开更多
关键词 xiang Lin’s WIFE TESS TRAGEDY Comparison
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Optimal storage temperature and 1-MCP treatment combinations for different marketing times of Korla Xiang pears 被引量:15
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作者 JIA Xiao-hui WANG Wen-hui +3 位作者 DU Yan-min TONG Wei WANG Zhi-hua Hera Gul 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2018年第3期693-703,共11页
Maintenance of green color is the primary indicator of quality in the market evaluation of Korla Xiang pears at present and can generally be achieved through early harvesting and decreasing the storage temperature, bu... Maintenance of green color is the primary indicator of quality in the market evaluation of Korla Xiang pears at present and can generally be achieved through early harvesting and decreasing the storage temperature, but the fruit quality was reduced by early harvesting, and the decreasing storage temperature increased the risk of chilling injury. The objectives of this study were to determine the optimal storage parameters for different storage times and to find ways to preserve the green skin color of pears. Specifically, we analyzed the effects of the ethylene inhibitor, 1-methylcyclopropene (1-MCP), combined with low temperature on quality and maintenance of the green color of Korla Xiang pears during storage. We found that 1-MCP and/or low temperature reduced the loss of green color at 20℃ after being removed from cold storage. In addition, 1-MCP significantly inhibited the decline of titratable acid and ascorbic acid but had no significant effect on fruit firmness and total soluble solids. Low temperature with or without 1-MCP inhibited the release of ethylene, inhibited the decline in the stalk preservation index, inhibited the increase in decay rate and weight loss rate during storage, and inhibited the increase in the core browning index after 225 days of storage. Different storage temperatures had different effects on the quality of Korla Xiang pears. Despite inhibiting ethylene release, a storage temperature of-1.5℃ increased the respiration rate. Storage at -1.5℃ caused core browning eady during storage due to chilling injury, whereas at 2℃ core browning occurred late during storage due to senescence. In late storage, 1-MCP had no significant effect on the maintenance of Korla Xiang pear quality at 2℃. Based on these results, we determined the optimal combinations of low temperature and 1-MCP treatment to maintain pear quality while avoiding chilling injury. For different marketing times, the optimal conditions for storage until New Year's Day (a storage duration of 90 days) are 2℃ or 1-MCP combined with 2℃. For storage until the Spring Festival (a storage duration of 150 days), the optimal conditions are 0℃ or 1-MCP combined with 0℃, and for storage until May (a storage duration of 225 days), the best conditions are 1-MCP combined with -1.5℃. 展开更多
关键词 low temperature 1-methylcyclopropene Korla xiang pear maintenance of green color QUALITY
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Genomic and transcriptomic analyses reveal selection of genes for puberty in Bama Xiang pigs 被引量:9
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作者 Yang Yang Adeniyi C.Adeola +1 位作者 Hai-Bing Xie Ya-Ping Zhang 《Zoological Research》 SCIE CAS CSCD 2018年第6期424-430,共7页
The Bama Xiang pig (BMX) Chinese indigenous breed is a famous early-maturing with a two-end black coat To uncover the genetic basis of the BMX phenotype, we conducted comparative genomic analyses between BMX and Eas... The Bama Xiang pig (BMX) Chinese indigenous breed is a famous early-maturing with a two-end black coat To uncover the genetic basis of the BMX phenotype, we conducted comparative genomic analyses between BMX and East Asian wild boars and Laiwu pigs, respectively. Genes under positive selection were enriched in pathways associated with gonadal hormone and melanin synthesis, consistent with the phenotypic changes observed during development in BMX pigs. We also performed differentially expressed gene analysis based on RNA-seq data from pituitary tissues of BMX and Large White pigs. The CTTNBP2NL, FRS2, KANK4, and KATNAL1 genes were under selection and exhibited expressional changes in the pituitary tissue, which may affect BMX pig puberty. Our study demonstrated the positive selection of early maturity in the development of BMX pigs and advances our knowledge on the role of regulatory elements in puberty evolution in pigs. 展开更多
关键词 Puberty Bama xiang pig PITUITARY Differentially expressed genes
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Xiang荷中天然色素的提取及其稳定性的研究 被引量:3
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作者 麻明友 许德政 《吉首大学学报》 1993年第6期95-98,共4页
本文研究以Xiang荷为原料,用水作为溶剂提取出成本低廉,安全性高的天然紫色色素的方法。该色素水溶液的最大吸收波长为280nm。Xiang荷色素在酸性条件下稳定,呈紫色,在碱性条件下为棕褐色。该色素的热稳定性好,光照有利于显色,耐... 本文研究以Xiang荷为原料,用水作为溶剂提取出成本低廉,安全性高的天然紫色色素的方法。该色素水溶液的最大吸收波长为280nm。Xiang荷色素在酸性条件下稳定,呈紫色,在碱性条件下为棕褐色。该色素的热稳定性好,光照有利于显色,耐一定的还原性,但耐氧性较差。 展开更多
关键词 天然色素 提取 稳定性 xiang 紫色色素 酸性条件 碱性条件 水溶液 热稳定性 耐氧化性 光照 还原性
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Cultural interpretation on Xiang thinking of Traditional Chinese Medicine 被引量:1
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作者 Jialing Mao Chen Wang 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2013年第4期545-548,共4页
Though the analysis on the characteristics of Xiang thinking and the cultural background of its formation, it is believed that Xiang thinking is not only an art of logic and thinking with the natural holistic view but... Though the analysis on the characteristics of Xiang thinking and the cultural background of its formation, it is believed that Xiang thinking is not only an art of logic and thinking with the natural holistic view but also represents the most important cognitive patterns concerning knowledge system of Traditional Chinese Medicine, and even it is the soul of Traditional Chinese Medicine culture. Therefore, a new viewpoint has been proposed that it is necessary to adhere to Xiang thinking with the study of Xiang as a core procedure and to seek for breakthrough for academic innovation in the cognitive process of Xiang with efforts. 展开更多
关键词 MEDICINE Chinese traditional xiang thinking Academic innovation
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Variation of Serum Protein Level in Xiang Piglets at Different Month of Age
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作者 Chi Yujie, Gao Xuejun, Yan Libo(Northeast Agricultural University, Harbin 150030, P R C) 《Journal of Northeast Agricultural University(English Edition)》 CAS 1995年第2期118-122,共5页
Usual clinieal methods were used to determine the concentrations of scrum protein, albumin and globulin in Xiang piglets from the 1st month to the 6th month of age. Thirteen piglcts(cight males and five females) born ... Usual clinieal methods were used to determine the concentrations of scrum protein, albumin and globulin in Xiang piglets from the 1st month to the 6th month of age. Thirteen piglcts(cight males and five females) born in Spring were selected from the Livestock Experimental Station of NEAU. The results showed that the scrum protein level was different at different month of age. The lowest level was found at the 1st month of age, and the highest at the 4th month of age. The difference in scrum protein concentration was significant between different months of age. There was, however, no significant difference between sexes at the same month of age. 展开更多
关键词 xiang piglet BLOOD PROTEIN VARIATION
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Experimental Study and Clinical Observation on Therapy of Chronic Gastritis with Shen Xiang Yang Wei San.
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作者 Sun Guihua 《Journal of Medical Colleges of PLA(China)》 CAS 1990年第2期127-127,共1页
According to the basic theory of the tradi-tional Chinese medicine,we have composed aprescription called Shen Xiang Yang Wei San(SXYWS,a powder)to treat chronic gastritis.After intravenous injection,it can evidently i... According to the basic theory of the tradi-tional Chinese medicine,we have composed aprescription called Shen Xiang Yang Wei San(SXYWS,a powder)to treat chronic gastritis.After intravenous injection,it can evidently incr- 展开更多
关键词 xiang INTRAVENOUS GASTRITIS Observation absolute 乡司 blind
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Characteristics of High Quality Rice Xiang 5 and the Supporting Cultivation Techniques
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作者 Deze XU Haiya CAI +2 位作者 Feng ZHAO Jianping WU Aiqing YOU 《Asian Agricultural Research》 2016年第3期72-73,共2页
The high quality rice,Xiang 5,is a new strain bred by Institute of Food Crops of Hubei Academy of Agricultural Sciences which first hybridizes Chinese scented rice with 9311,and then re-crosses it with Ezhong 5 for co... The high quality rice,Xiang 5,is a new strain bred by Institute of Food Crops of Hubei Academy of Agricultural Sciences which first hybridizes Chinese scented rice with 9311,and then re-crosses it with Ezhong 5 for continuous generations. The strain has good quality,high yield,suitable maturity period,strong scent,strong combining ability and other features. This paper summarizes the appearance characteristics of Xiang 5 and main points of the supporting cultivation techniques,aimed at providing technical support and theoretical reference for its field production. 展开更多
关键词 High QUALITY RICE xiang 5 CHARACTERISTICS CULTIVATION TECHNIQUES
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Study on Leaching Conditions of Miao Medicine Xiange Zuyu Powder
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作者 Yuanfeng YANG Yuchuan LI +2 位作者 Renhui YANG Lida CHEN Qiqian CHEN 《Agricultural Biotechnology》 CAS 2022年第3期103-105,共3页
[Objectives]This study was conducted to optimize the soaking conditions of Miao medicine Xiange Zuyu Powder.[Methods]With the water-soluble extract as an investigation index,an L_(9)(3^(4))orthogonal test was carried ... [Objectives]This study was conducted to optimize the soaking conditions of Miao medicine Xiange Zuyu Powder.[Methods]With the water-soluble extract as an investigation index,an L_(9)(3^(4))orthogonal test was carried out to investigate the amount of water added,soaking temperature,soaking times and soaking time,and the best soaking conditions for Xiange Zuyu Powder were screened.[Results]The optimal soaking conditions were as follows:adding 1000 ml of boiling water at 100℃,soaking for 20 min each time,3 times in total.[Conclusions]The soaking scheme is reasonable and can provide a reasonable basis for clinical medication. 展开更多
关键词 xiange Zuyu Powder Soaking conditions Orthogonal test Water soluble extract
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Mu-Xiang-You-Fang protects PC12 cells against OGD/R-induced autophagy via AMPK/mTOR signaling pathway
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作者 MA Hui-xia CHEN Ai-ling +3 位作者 HOU Fan LI Ting-ting ZHU Ya-fei ZHAO Qi-peng 《中国药理学与毒理学杂志》 CAS 北大核心 2019年第9期742-743,共2页
OBJECTIVE Mu-Xiang-You-Fang(MXYF)is a classic prescription of Hui medicine,composed of five herbs,which has been used to treat ischemic stroke for many years.However,the potential pharmacological mecha⁃nisms of MXYF r... OBJECTIVE Mu-Xiang-You-Fang(MXYF)is a classic prescription of Hui medicine,composed of five herbs,which has been used to treat ischemic stroke for many years.However,the potential pharmacological mecha⁃nisms of MXYF remain unclear.The present research is to investigate the neuroprotective effect of MXYF and its role in modulating autophagy via AMPK/mTOR signaling pathway in the PC12 oxygen-glucose deprivation and reperfusion(OGD/R)injury model.METHODS MXYF was extracted by supercritical CO2 fluid extraction apparatus.PC12 OGD/R injury model was established by oxygen-glucose deprivation for 2 h and reperfusion for 24 h.The effects of MXYF on the viability and cytotoxicity of PC12 cells were determined through cell counting kit(CCK-8)assay.Colorimetric method was performed to determine the LDH leakage rate.The calcium concentration was determined by chemical fluorescence method and the mitochondrial membrane potential was determined through flow cytometry.Monodansylcadaverine(MDC)staining was conducted to detect autophagosome formation.The expression of LC3,Beclin1,p62,p-AMPK,ULK1,p-mTOR and p-p70s6k proteins were determined by immunofluorescence and Western blotting analyses.RESULTS MXYF(1,2 and 4 mg·L^-1)could significantly increase the cell viability and mitochondrial membrane potential,while decreased the release of lactate dehydrogenase(LDH)and calcium concentration in PC12 cells.Mechanistic studies showed that MXYF reduced the LC3-II/LC3-I ratio and inhibited the expression of beclin1,p-AMPK and ULK1.In comparison,the expres⁃sion of p-mTOR,p-p70s6k and p62 were significantly enhanced.CONCLUSION MXYF inhibits autophagy after OGD/Rinduced PC12 cell injury through AMPK-mTOR pathway,thus MXYF might have therapeutic potential for treating the ischemic stroke. 展开更多
关键词 Mu-xiang-You-Fang PC12 cells oxygen-glucose deprivation and reperfusion AUTOPHAGY AMPK/mTOR pathway
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The Influence of Miao Nationality’s Culture in Yuan Xiang Region on the Later Poetry Creation of Qu Yuan
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作者 GUO Xiaochun 《Cultural and Religious Studies》 2020年第8期467-472,共6页
Miao culture is one of the minority cultures in China.It also has a certain impact on the development of Chinese literature and poetry.Chu ci is a new poetic style created by Qu Yuan,an ancient poet in China.It is the... Miao culture is one of the minority cultures in China.It also has a certain impact on the development of Chinese literature and poetry.Chu ci is a new poetic style created by Qu Yuan,an ancient poet in China.It is the first collection of romantic poetry in the history of Chinese literature.Qu Yuan’s poetry creation is related to his life experience.Qu Yuan was exiled to Yuan Xiang region,and he had been in contact with the Miao ancestors in Yuan Xiang area during the exile.Therefore,the Miao land culture in Yuan Xiang area has a profound influence on Qu Yuan’s later poetry creation.This paper,taking Qu Yuan’s later poetry as an example,analyzes the influence of Miao culture on Chu ci in Yuan Xiang area,introduces Qu Yuan’s life and how to contact Miao culture,and probes into the influence of Miao nationality’s religious thought,customs,language and culture,oral folk song and pan song on the later poetry creation of Qu Yuan. 展开更多
关键词 Miao nationality’s culture the songs of Chu influence Qu Yuan’s poetry Yuan xiang region
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China's highest steel pipe towers of Taishan-Xiangshan transmission project in Guangdong
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《Electricity》 2005年第A04期5-5,共1页
The 500-kV Tai-Xiang transmission line project has completed 80% of the total construction engineering at the beginning of November this year. Yamen waterway-crossing project, an important part of the line, has been t... The 500-kV Tai-Xiang transmission line project has completed 80% of the total construction engineering at the beginning of November this year. Yamen waterway-crossing project, an important part of the line, has been topped at present. Two steel-pipe towers crossing Xijiang River’s Yamen waterway is 215.5-m high each. The distance between the 展开更多
关键词 CROSSING completed GUANGDONG PIPE xiang BEGINNING
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WTA·Xianghu Dialogue 2020 Held in China
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作者 Gu Yue 《China & The World Cultural Exchange》 2020年第12期38-39,共2页
The"World Tourism Alliance(WTA)·Xianghu Dialogue 2020"was held in Hangzhou,Zhejiang Province,China from November 13 to 14,2020.Themed"Shaping the Future:Rebuilding Confidence&Embracing the New ... The"World Tourism Alliance(WTA)·Xianghu Dialogue 2020"was held in Hangzhou,Zhejiang Province,China from November 13 to 14,2020.Themed"Shaping the Future:Rebuilding Confidence&Embracing the New Normal in Travel&Tourism",the two-days event invited experts,scholars and professionals from 24 countries and regions to discuss the development of tourism under the impact of COVID-19. 展开更多
关键词 ALLIANCE xiang CONFIDENCE
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Yu Xiangzhi:Presenting Working People's Enthusiasm and Dedication in the New Era via Paintings
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作者 Tian Xin 《China & The World Cultural Exchange》 2024年第3期36-37,共2页
In recent years,artist Yu Xiangzhi has focused on the new outlook of the working people in the new era and created a series of portraits called "Paean to Heroes",presenting working people's enthusiasm an... In recent years,artist Yu Xiangzhi has focused on the new outlook of the working people in the new era and created a series of portraits called "Paean to Heroes",presenting working people's enthusiasm and dedication in the new era with paintings.He hopes that this series of works can resonate with the public,who will pay more attention to the life and working conditions of grassroots workers.Recently,this magazine has interviewed Yu Xiangzhi and talked about the story behind the creation of his "Paean to Heroes"series of oil paintings. 展开更多
关键词 INTERVIEW xiang ZHI
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Xiangguosi Gas Storage:the First Underground Gas Storage in the Southwest
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《China Oil & Gas》 CAS 2020年第5期9-11,共3页
Entering the 21st century,with the adjustment of China's energy consumption structure strategy and a more urgent demand for clean energy by the sustainable development of the national economy,the annual consumptio... Entering the 21st century,with the adjustment of China's energy consumption structure strategy and a more urgent demand for clean energy by the sustainable development of the national economy,the annual consumption of natural gas,a kind of clean energy,has increased rapidly,and China's natural gas industry has also entered a period of rapid development,which puts forward higher requirements not only for China's natural gas exploration and development,but also for natural gas storage and supply. 展开更多
关键词 STORAGE xiang URGENT
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Blue Calico Printing and Dyeing Craft in Tongxiang
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《China Today》 2024年第8期73-73,共1页
BLUE calico is a traditional Chinese handmade printed fabric.Dyed in indigo,it has a blue base with white patterns.Tongxiang,a city in east China’s Zhejiang Province,is well-known for printing and dyeing blue calico.... BLUE calico is a traditional Chinese handmade printed fabric.Dyed in indigo,it has a blue base with white patterns.Tongxiang,a city in east China’s Zhejiang Province,is well-known for printing and dyeing blue calico.The craft boasts a history of a millennium in the town with its heyday in the Tang(618-907)and Song(960-1279)dynasties.The technique was widely applied by the general public during the Ming and Qing dynasties(1368-1911). 展开更多
关键词 DYEING PRINTING xiang
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WTA ‘Xianghu Dialogue' 2022 Opens in Hangzhou
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《China & The World Cultural Exchange》 2023年第3期26-28,共3页
From February 24 to 25,World Tourism Alliance(WTA)"Xianghu Dialogue"2022 was held in Hangzhou,Zhejiang Province,under the theme of"Harmonious Symbiosis:A New Paradigm for a New Tourism"to build con... From February 24 to 25,World Tourism Alliance(WTA)"Xianghu Dialogue"2022 was held in Hangzhou,Zhejiang Province,under the theme of"Harmonious Symbiosis:A New Paradigm for a New Tourism"to build consensus and promote cooperation. 展开更多
关键词 ALLIANCE Hangzhou xiang
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