现代汉语中“雪白、稀烂、稀糟”等状态词在词法上包括状中式复合词和附加前缀的派生词,“稀”这样的成分属于表增量的评价性前缀。经历时考察发现,XA式状态词经历了如下演变过程:如/若/似+XP+A(比拟结构)/Ad+A(状中短语)/A 1 A 2(并列...现代汉语中“雪白、稀烂、稀糟”等状态词在词法上包括状中式复合词和附加前缀的派生词,“稀”这样的成分属于表增量的评价性前缀。经历时考察发现,XA式状态词经历了如下演变过程:如/若/似+XP+A(比拟结构)/Ad+A(状中短语)/A 1 A 2(并列式复合词)→XA式复合词→xA式派生词。XA式复合词的形成是词汇化的过程,具体的复合词有不同的词汇化来源。xA式派生词是词法化的结果,增量前缀是复合词的构成成分经类推扩展而来。XA式复合词在明清时期出现了一系列词法变化形式,在现代汉语中出现了主观义磨损的趋势,这些变化均可以通过评价性形态的演变规律得到解释。展开更多
In marker-assisted breeding for bacterial blight(BB) resistance in rice, three major resistance genes, viz., Xa21, xa13 and xa5, are routinely deployed either singly or in combinations. As efficient and functional mar...In marker-assisted breeding for bacterial blight(BB) resistance in rice, three major resistance genes, viz., Xa21, xa13 and xa5, are routinely deployed either singly or in combinations. As efficient and functional markers are yet to be developed for xa13 and xa5, we have developed simple PCR-based functional markers for both the genes. For xa13, we designed a functional PCR-based marker, xa13-prom targeting the In Del polymorphism in the promoter of candidate gene Os8N3 located on chromosome 8 of rice. With respect to xa5, a multiplex-PCR based functional marker system, named xa5 FM, consisting of two sets of primer pairs targeting the 2-bp functional nucleotide polymorphism in the exon II of the gene TFIIA5(candidate for xa5), has been developed. Both xa13-prom and xa5 FM can differentiate the resistant and susceptible alleles for xa13 and xa5, respectively, in a co-dominant fashion. Using these two functional markers along with the already reported functional PCR-based marker for Xa21(p TA248), we designed a single-tube multiplex PCR based assay for simultaneous detection of all the three major resistance genes and demonstrated the utility of the multiplex marker system in a segregating population.展开更多
The title compound （zifaxaban 2, C20HI6C1N3O4S, Mr = 429.87） was synthesized and its crystal structure was determined by single-crystal X-ray diffraction. Zifaxaban crystallizes in monoclinic, space group P21 with a...The title compound （zifaxaban 2, C20HI6C1N3O4S, Mr = 429.87） was synthesized and its crystal structure was determined by single-crystal X-ray diffraction. Zifaxaban crystallizes in monoclinic, space group P21 with a = 5.7900（12）, b = 13.086（3）, c = 12.889（3） A, β= 100.86（3）°, V = 959.1（3） ）k3, Z = 2, Dc= 1.489 g/cm3, F（000） = 444,μ= 0.342 mm-l, the final R = 0.0320 and wR = 0.0640 for 2717 observed reflections （I 〉 20（I）. The absolute configuration of the stereogenic center in the title compound was confirmed to be S by single-crystal X-ray diffraction. Four existing intermolecular hydrogen bonds help to stabilize the lattice and the molecule in the lattice to adopt an L-shape conformation. Zifaxaban was slightly more active than rivaroxaban 1 in in vitro assay against human FXa and therefore is promising as a drug candidate.展开更多
文摘现代汉语中“雪白、稀烂、稀糟”等状态词在词法上包括状中式复合词和附加前缀的派生词,“稀”这样的成分属于表增量的评价性前缀。经历时考察发现,XA式状态词经历了如下演变过程:如/若/似+XP+A(比拟结构)/Ad+A(状中短语)/A 1 A 2(并列式复合词)→XA式复合词→xA式派生词。XA式复合词的形成是词汇化的过程,具体的复合词有不同的词汇化来源。xA式派生词是词法化的结果,增量前缀是复合词的构成成分经类推扩展而来。XA式复合词在明清时期出现了一系列词法变化形式,在现代汉语中出现了主观义磨损的趋势,这些变化均可以通过评价性形态的演变规律得到解释。
基金the funding support provided by the Department of Biotechnology(DBT),Government of India(Grant Nos.BT/AB/FG-2 (PH-II)/2009 and BT/PR11705/AGR/02/646/2008)
文摘In marker-assisted breeding for bacterial blight(BB) resistance in rice, three major resistance genes, viz., Xa21, xa13 and xa5, are routinely deployed either singly or in combinations. As efficient and functional markers are yet to be developed for xa13 and xa5, we have developed simple PCR-based functional markers for both the genes. For xa13, we designed a functional PCR-based marker, xa13-prom targeting the In Del polymorphism in the promoter of candidate gene Os8N3 located on chromosome 8 of rice. With respect to xa5, a multiplex-PCR based functional marker system, named xa5 FM, consisting of two sets of primer pairs targeting the 2-bp functional nucleotide polymorphism in the exon II of the gene TFIIA5(candidate for xa5), has been developed. Both xa13-prom and xa5 FM can differentiate the resistant and susceptible alleles for xa13 and xa5, respectively, in a co-dominant fashion. Using these two functional markers along with the already reported functional PCR-based marker for Xa21(p TA248), we designed a single-tube multiplex PCR based assay for simultaneous detection of all the three major resistance genes and demonstrated the utility of the multiplex marker system in a segregating population.
基金Supported by Key Projects of Tianjin Science and Technology Support Plan(12ZCZDSY01100)
文摘The title compound （zifaxaban 2, C20HI6C1N3O4S, Mr = 429.87） was synthesized and its crystal structure was determined by single-crystal X-ray diffraction. Zifaxaban crystallizes in monoclinic, space group P21 with a = 5.7900（12）, b = 13.086（3）, c = 12.889（3） A, β= 100.86（3）°, V = 959.1（3） ）k3, Z = 2, Dc= 1.489 g/cm3, F（000） = 444,μ= 0.342 mm-l, the final R = 0.0320 and wR = 0.0640 for 2717 observed reflections （I 〉 20（I）. The absolute configuration of the stereogenic center in the title compound was confirmed to be S by single-crystal X-ray diffraction. Four existing intermolecular hydrogen bonds help to stabilize the lattice and the molecule in the lattice to adopt an L-shape conformation. Zifaxaban was slightly more active than rivaroxaban 1 in in vitro assay against human FXa and therefore is promising as a drug candidate.
