An automatic dependent surveillance-broadcast(ADS-B)system has serious security problems,and the data can be spoofed during broadcasting precise position information of aircraft.A solution of the ADS-B system data aut...An automatic dependent surveillance-broadcast(ADS-B)system has serious security problems,and the data can be spoofed during broadcasting precise position information of aircraft.A solution of the ADS-B system data authentication based on the elliptic curve cipher(ECC)and X.509 certificate is proposed.It can avoid the key distribution problem by using the symmetric key algorithm and prevent the ADS-B data from being spoofed thoroughly.Experimental test results show that the solution is valid and appropriate in ADS-B universal access transceiver(UAT)mode.展开更多
基金supported by the National Natural Science Foundation of China under Grant No.61179072the Civil Aviation Science Foundation of China
文摘An automatic dependent surveillance-broadcast(ADS-B)system has serious security problems,and the data can be spoofed during broadcasting precise position information of aircraft.A solution of the ADS-B system data authentication based on the elliptic curve cipher(ECC)and X.509 certificate is proposed.It can avoid the key distribution problem by using the symmetric key algorithm and prevent the ADS-B data from being spoofed thoroughly.Experimental test results show that the solution is valid and appropriate in ADS-B universal access transceiver(UAT)mode.
文摘目的了解微小RNA(micro RNA,miR)miR-509-3p和XIAP表达对肝癌细胞增殖侵袭能力的影响及其作用机制。方法应用实时定量PCR(RT-PCR)检测107例肝癌患者肝癌组织和癌旁组织中miR-509-3p和XIAP表达,利用细胞增殖实验和Transwell侵袭实验观察转染miR-509-3p类似物和抑制剂的HepG2细胞、RNA干扰XIAP表达的HepG2细胞的增殖和侵袭能力。结果肝癌组织miR-509-3p与XIAP的相对表达量分别为0.415±0.098、1.657±0.147,癌旁组织miR-509-3p与XIAP的相对表达量分别为1.127±0.126、0.425±0.113,癌组织中miR-509-3p相对表达量显著低于癌旁组织,差异有统计学意义(t=3.257,P=0.002),而XIAP的相对表达量显著偏高(t=4.201,P=0.000)。肝癌组织miR-509-3p与XIAP mRNA表达水平呈负相关(r=0.218,P=0.046)。与对照组相比,转染miR-509-3p类似物48、72、96及120 h时,HepG2细胞增殖率明显偏低,差异有统计学意义(均P<0.05);与对照组相比,转染miR-509-3p抑制剂48 h后HepG2细胞增殖明显偏高(P均<0.05),与对照组相比,转染miR-509-3p类似物后24 h HepG2细胞侵袭数目明显较低,分别为96.32±0.52、51.47±0.45,差异有统计学意义(t=2.263,P=0.021);与对照组相比,转染miR-509-3p抑制剂后24 h HepG2细胞侵袭数目明显较高,分别为94.65±0.42、120.14±0.45,差异有统计学意义(t=2.463,P=0.013)。结论 miR-509-3p与XIAP的表达与肝癌细胞的增殖与侵袭能力有关,miR-509-3p表达可能通过影响XIAP表达而发挥调节肝癌细胞增殖和侵袭能力的作用。
