An automatic dependent surveillance- broadcast （ADS-B） system has serious security problems, and the data can be spoofed during broadcasting precise position information of aircraft. A solution of the ADS-B system d...An automatic dependent surveillance- broadcast （ADS-B） system has serious security problems, and the data can be spoofed during broadcasting precise position information of aircraft. A solution of the ADS-B system data authentication based on the elliptic curve cipher （ECC） and X.509 certificate is proposed. It can avoid the key distribution problem by using the symmetric key algorithm and prevent the ADS-B data from being spoofed thoroughly. Experimental test results show that the solution is valid and appropriate in ADS-B universal access transceiver （UAT） mode.展开更多
基金supported by the National Natural Science Foundation of China under Grant No. 61179072the Civil Aviation Science Foundation of China
文摘An automatic dependent surveillance- broadcast （ADS-B） system has serious security problems, and the data can be spoofed during broadcasting precise position information of aircraft. A solution of the ADS-B system data authentication based on the elliptic curve cipher （ECC） and X.509 certificate is proposed. It can avoid the key distribution problem by using the symmetric key algorithm and prevent the ADS-B data from being spoofed thoroughly. Experimental test results show that the solution is valid and appropriate in ADS-B universal access transceiver （UAT） mode.
文摘目的了解微小RNA(micro RNA,miR)miR-509-3p和XIAP表达对肝癌细胞增殖侵袭能力的影响及其作用机制。方法应用实时定量PCR(RT-PCR)检测107例肝癌患者肝癌组织和癌旁组织中miR-509-3p和XIAP表达,利用细胞增殖实验和Transwell侵袭实验观察转染miR-509-3p类似物和抑制剂的HepG2细胞、RNA干扰XIAP表达的HepG2细胞的增殖和侵袭能力。结果肝癌组织miR-509-3p与XIAP的相对表达量分别为0.415±0.098、1.657±0.147,癌旁组织miR-509-3p与XIAP的相对表达量分别为1.127±0.126、0.425±0.113,癌组织中miR-509-3p相对表达量显著低于癌旁组织,差异有统计学意义(t=3.257,P=0.002),而XIAP的相对表达量显著偏高(t=4.201,P=0.000)。肝癌组织miR-509-3p与XIAP mRNA表达水平呈负相关(r=0.218,P=0.046)。与对照组相比,转染miR-509-3p类似物48、72、96及120 h时,HepG2细胞增殖率明显偏低,差异有统计学意义(均P<0.05);与对照组相比,转染miR-509-3p抑制剂48 h后HepG2细胞增殖明显偏高(P均<0.05),与对照组相比,转染miR-509-3p类似物后24 h HepG2细胞侵袭数目明显较低,分别为96.32±0.52、51.47±0.45,差异有统计学意义(t=2.263,P=0.021);与对照组相比,转染miR-509-3p抑制剂后24 h HepG2细胞侵袭数目明显较高,分别为94.65±0.42、120.14±0.45,差异有统计学意义(t=2.463,P=0.013)。结论 miR-509-3p与XIAP的表达与肝癌细胞的增殖与侵袭能力有关,miR-509-3p表达可能通过影响XIAP表达而发挥调节肝癌细胞增殖和侵袭能力的作用。
