AIM To assess whether elevated serum carcinoembryonic antigen(CEA) is in the inferior prognosis for pathological lymph node-negative(p N_0) gastric cancer(GC) patients who underwent D_2 gastrectomy.METHODS About 469 p...AIM To assess whether elevated serum carcinoembryonic antigen(CEA) is in the inferior prognosis for pathological lymph node-negative(p N_0) gastric cancer(GC) patients who underwent D_2 gastrectomy.METHODS About 469 p N0 GC patients,who received D^2 radical gastrectomy were retrospectively analyzed. The X-tile plots cut-off point for CEA were 30.02 ng/m L using minimum P-value from log-rank χ~2 statistics,and p N_0 GC patients were assigned to two groups: those more than 30.02 ng/m L(n = 48;CEA-high group) and those less than 30.02 ng/m L(n = 421;CEA-low group). Clinicopathologic characteristics were compared usingPearson's χ2 or Fisher's exact tests,and survival curves were so manufactured using the Kaplan-Meier method. Univariate and multivariate analysis were carried out using the logistic regression method.RESULTS The percentage of vessel carcinoma embolus(31.35% vs 17.1%) and advanced GC(T_(2-4b))(81.25% vs 65.32%) were higher in CEA-high group than CEA-low group. The CEA-positive patients had a significantly poorer prognosis than the CEA-nagetive patients in terms of overall survival(57.74% vs 90.69%,P < 0.05),and no different was found between subgroup of T category,differentiation,nerve invasion,and vessel carcinoma embolus(all P > 0.05). Multivariate survival analysis showed that CEA(OR = 4.924),and T category(OR = 2.214) were significant prognostic factors for stage p N0 GC(all P < 0.05). Besides,only T category(OR = 1.962) was an independent hazard factor in the CEA-high group(P < 0.05).CONCLUSION Those pretreatment serum CEA levels over 30.02 ng/m L on behalf of worse characteristics and unfavourable tumor behavior,and a poor prognosis for a nearly doubled risk of mortality in GC patients.展开更多
The main objective of this paper is to study the mineralogical composition and the environmental conditions of the Subiyah clay to be used for crafting pottery and technological behaviour that allows the evaluation of...The main objective of this paper is to study the mineralogical composition and the environmental conditions of the Subiyah clay to be used for crafting pottery and technological behaviour that allows the evaluation of the applicability of the clay deposits in manufacturing new ceramic products at Kuwait. This research could help artists, crafters of potters, and ceramic manufactures in Kuwait to depend on inland clay and this makes it easier for more production in ceramic and pottery in the future. All this could enhance the cultural of ceramic in teaching or producing it in Kuwaitfor the first time. For that purpose, six stations were selected at North-eastern part (Subiyah area) of Kuwait for clay investigation. X-ray Diffraction method (XRD) was led to identify mineralogical composition of samples;S1, S2, S3, S4A, S4B, and S6 were quartz, Calcite (Caco3), Dolomite, Illite and Clinochlore. Whereas;Quartz, Calcite Dolomite, Palygorskite, Nontronite and Clinochlore were recorded at S5 and S7. Clay mineralogical and environmental studies at our study area proved that, crafter can depend on Subiyah clay better than importing it from abroad.展开更多
基金Supported by Domestic Support from Young and Middle-aged key personnel Training program for provincial Health planning Students,No.2017-ZQN-18provincial Youth Health Science Research project,No.2014-2-8 and No.2017-1-13National key Clinical Specialty Construction project,No.2013-2016
文摘AIM To assess whether elevated serum carcinoembryonic antigen(CEA) is in the inferior prognosis for pathological lymph node-negative(p N_0) gastric cancer(GC) patients who underwent D_2 gastrectomy.METHODS About 469 p N0 GC patients,who received D^2 radical gastrectomy were retrospectively analyzed. The X-tile plots cut-off point for CEA were 30.02 ng/m L using minimum P-value from log-rank χ~2 statistics,and p N_0 GC patients were assigned to two groups: those more than 30.02 ng/m L(n = 48;CEA-high group) and those less than 30.02 ng/m L(n = 421;CEA-low group). Clinicopathologic characteristics were compared usingPearson's χ2 or Fisher's exact tests,and survival curves were so manufactured using the Kaplan-Meier method. Univariate and multivariate analysis were carried out using the logistic regression method.RESULTS The percentage of vessel carcinoma embolus(31.35% vs 17.1%) and advanced GC(T_(2-4b))(81.25% vs 65.32%) were higher in CEA-high group than CEA-low group. The CEA-positive patients had a significantly poorer prognosis than the CEA-nagetive patients in terms of overall survival(57.74% vs 90.69%,P < 0.05),and no different was found between subgroup of T category,differentiation,nerve invasion,and vessel carcinoma embolus(all P > 0.05). Multivariate survival analysis showed that CEA(OR = 4.924),and T category(OR = 2.214) were significant prognostic factors for stage p N0 GC(all P < 0.05). Besides,only T category(OR = 1.962) was an independent hazard factor in the CEA-high group(P < 0.05).CONCLUSION Those pretreatment serum CEA levels over 30.02 ng/m L on behalf of worse characteristics and unfavourable tumor behavior,and a poor prognosis for a nearly doubled risk of mortality in GC patients.
文摘The main objective of this paper is to study the mineralogical composition and the environmental conditions of the Subiyah clay to be used for crafting pottery and technological behaviour that allows the evaluation of the applicability of the clay deposits in manufacturing new ceramic products at Kuwait. This research could help artists, crafters of potters, and ceramic manufactures in Kuwait to depend on inland clay and this makes it easier for more production in ceramic and pottery in the future. All this could enhance the cultural of ceramic in teaching or producing it in Kuwaitfor the first time. For that purpose, six stations were selected at North-eastern part (Subiyah area) of Kuwait for clay investigation. X-ray Diffraction method (XRD) was led to identify mineralogical composition of samples;S1, S2, S3, S4A, S4B, and S6 were quartz, Calcite (Caco3), Dolomite, Illite and Clinochlore. Whereas;Quartz, Calcite Dolomite, Palygorskite, Nontronite and Clinochlore were recorded at S5 and S7. Clay mineralogical and environmental studies at our study area proved that, crafter can depend on Subiyah clay better than importing it from abroad.
