The fast X-ray imaging beamline(BL16U2)at Shanghai Synchrotron Radiation Facility(SSRF)is a new beamline that provides X-ray micro-imaging capabilities across a wide range of time scales,spanning from 100 ps toμs and...The fast X-ray imaging beamline(BL16U2)at Shanghai Synchrotron Radiation Facility(SSRF)is a new beamline that provides X-ray micro-imaging capabilities across a wide range of time scales,spanning from 100 ps toμs and ms.This beamline has been specifically designed to facilitate the investigation of a wide range of rapid phenomena,such as the deformation and failure of materials subjected to intense dynamic loads.In addition,it enables the study of high-pressure and high-speed fuel spray processes in automotive engines.The light source of this beamline is a cryogenic permanent magnet undulator(CPMU)that is cooled by liquid nitrogen.This CPMU can generate X-ray photons within an energy range of 8.7-30 keV.The beamline offers two modes of operation:monochromatic beam mode with a liquid nitrogen-cooled double-crystal monochromator(DCM)and pink beam mode with the first crystal of the DCM out of the beam path.Four X-ray imaging methods were implemented in BL16U2:single-pulse ultrafast X-ray imaging,microsecond-resolved X-ray dynamic imaging,millisecond-resolved X-ray dynamic micro-CT,and high-resolution quantitative micro-CT.Furthermore,BL16U2 is equipped with various in situ impact loading systems,such as a split Hopkinson bar system,light gas gun,and fuel spray chamber.Following the completion of the final commissioning in 2021 and subsequent trial operations in 2022,the beamline has been officially available to users from 2023.展开更多
Awell-anticipated wide-field X-ray focusing imager,the Einstein Probe(EP,also named“Tianguan”in Chinese)has caught the eye of astronomers since its launch in January 2024.Initiated and sponsored by the Chinese Acade...Awell-anticipated wide-field X-ray focusing imager,the Einstein Probe(EP,also named“Tianguan”in Chinese)has caught the eye of astronomers since its launch in January 2024.Initiated and sponsored by the Chinese Academy of Sciences(CAS),and developed in cooperation with the European Space Agency(ESA).展开更多
A primary study on Processing in X - ray inspection of spot weld for aluminum alloy spot welding,in- cluding for background simulation,acquisition of ideal binary image, and extraction and identifi- cation of defec...A primary study on Processing in X - ray inspection of spot weld for aluminum alloy spot welding,in- cluding for background simulation,acquisition of ideal binary image, and extraction and identifi- cation of defect features was presented.展开更多
Laser wakefield accelerators(LWFAs)offer acceleration gradients up to 1000 times higher than those of conventional radio-frequency accelerators,offering a pathway to significantly more compact and cost-effective accel...Laser wakefield accelerators(LWFAs)offer acceleration gradients up to 1000 times higher than those of conventional radio-frequency accelerators,offering a pathway to significantly more compact and cost-effective accelerator systems.This breakthrough opens up new possibilities for laboratory-scale light sources.All-optical inverse Compton scattering(AOCS)sources driven by LWFAs produce high-brightness,quasimonochromatic X rays with micrometer-scale source sizes,delivering the spatial coherence and resolution required for X-ray phase-contrast imaging(XPCI).These features position AOCS X-ray sources as promising tools for applications in biology,medicine,physics,and materials science.However,previous AOCS-based imaging studies have primarily focused on X-ray absorption imaging.In this work,we report successful experimental demonstrations of edge-enhanced in-line XPCI using energy-tunable,quasi-monochromatic AOCS X rays.With a spatial resolution of~20μm,our results clearly show the potential of high-resolution,AOCS-based XPCI applications.展开更多
Scintillators have been widely used in X-ray imaging due to their ability to convert high-energy radiation into visible light,making them essential for applications such as medical imaging and high-energy physics.Rece...Scintillators have been widely used in X-ray imaging due to their ability to convert high-energy radiation into visible light,making them essential for applications such as medical imaging and high-energy physics.Recent advances in the artificial structuring of scintillators offer new opportunities for improving the energy resolution of scintillator-based X-ray detectors.Here,we present a three-bin energy-resolved X-ray imaging framework based on a three-layer multicolor scintillator used in conjunction with a physics-aware image postprocessing algorithm.The multicolor scintillator is able to preserve X-ray energy information through the combination of emission wavelength multiplexing and energy-dependent isolation of X-ray absorption in specific layers.The dominant emission color and the radius of the spot measured by the detector are used to infer the incident X-ray energy based on prior knowledge of the energy-dependent absorption profiles of the scintillator stack.Through ab initio Monte Carlo simulations,we show that our approach can achieve an energy reconstruction accuracy of 49.7%,which is only 2%below the maximum accuracy achievable with realistic scintillators.We apply our framework to medical phantom imaging simulations where we demonstrate that it can effectively differentiate iodine and gadolinium-based contrast agents from bone,muscle,and soft tissue.展开更多
Lanthanide(Ln)-based metal halides with excellent luminescence properties,large Stokes shifts,and low toxicity have aroused wide attention as scintillators for X-ray imaging.However,the lack of fast and mild synthesis...Lanthanide(Ln)-based metal halides with excellent luminescence properties,large Stokes shifts,and low toxicity have aroused wide attention as scintillators for X-ray imaging.However,the lack of fast and mild synthesis methods of Ln-based metal halides,as one of the technical challenges,limits their applications.Here,benefiting from the innovative selection of methanol and ethanol as the solvent and anti-solvent,respectively,a series of Cs3LnCl6(Ln=Ce,Pr,Nd,Sm,Eu,Gd,Tb,Dy,Ho,Er,Tm,Yb,Lu)microcrystals(MCs)were prepared via the recrystallization method at room temperature for the first time.This recrystallization method could also realize large-scale production at one time and recyclable recrystallization of single-element MCs and the preparation of high-entropy five-element Cs_(3){TbDy-HoErTm}_(1)Cl_(6) crystals.Among these Cs_(3)LnCl_(6)MCs,Cs_(3)TbCl_(6)MCs with 4f→ 5d absorption transition possess the highest photoluminescence quantum yield of 90.8%.Besides,under X-ray irradiation,Cs3TbCl6 MCs show a high light yield of~51,800 photons MeV^(-1) and the as-fabricated thin films possess promising X-ray imaging ability and excellent spatial resolutions(12 Ip mm^(-1)).This work provides a new method for ultrafast preparing Ln-based metal halides under mild synthetic conditions and highlights their excellent potential as scintillators for X-ray imaging.展开更多
The efficiency of N2-fixation in legume-rhizobia symbiosis is a function of root nodule activity.Nodules consist of 2 functionally important tissues:(a)a central infected zone(CIZ),colonized by rhizobia bacteria,which...The efficiency of N2-fixation in legume-rhizobia symbiosis is a function of root nodule activity.Nodules consist of 2 functionally important tissues:(a)a central infected zone(CIZ),colonized by rhizobia bacteria,which serves as the site of N2-fixation,and(b)vascular bundles(VBs),serving as conduits for the transport of water,nutrients,and fixed nitrogen compounds between the nodules and plant.A quantitative evaluation of these tissues is essential to unravel their functional importance in N2-fixation.Employing synchrotron-based x-ray microcomputed tomography(SR-μCT)at submicron resolutions,we obtained high-quality tomograms of fresh soybean root nodules in a non-invasive manner.A semi-automated segmentation algorithm was employed to generate 3-dimensional(3D)models of the internal root nodule structure of the CIZ and VBs,and their volumes were quantified based on the reconstructed 3D structures.Furthermore,synchrotron x-ray fluorescence imaging revealed a distinctive localization of Fe within CIZ tissue and Zn within VBs,allowing for their visualization in 2 dimensions.This study represents a pioneer application of the SR-μCT technique for volumetric quantification of CIZ and VB tissues in fresh,intact soybean root nodules.The proposed methods enable the exploitation of root nodule's anatomical features as novel traits in breeding,aiming to enhance N2-fixation through improved root nodule activity.展开更多
The Einstein Probe(EP)satellite represents a significant milestone in China's pursuit of advancing time-domain astronomy and high-energy astrophysics.At its core lies the Follow-up X-ray Telescope(FXT),a groundbre...The Einstein Probe(EP)satellite represents a significant milestone in China's pursuit of advancing time-domain astronomy and high-energy astrophysics.At its core lies the Follow-up X-ray Telescope(FXT),a groundbreaking payload that marks China's first foray into Wolter-I focusing technology for X-ray imaging.Designed with a dual-telescope structure,FXT incorporates 54 layers of ultra-smooth,gold-coated nickel mirror shells nested within each focusing mirror,paired with an advanced PNCCD focal plane detector,coupled with an advanced PNCCD focal plane detector.展开更多
For practical applications of X-ray ghost imaging(XGI),the imaging time is a major challenge.In this paper,we propose a fast XGI scheme based on a continuous translation mask with etched aggregate patterns.High contra...For practical applications of X-ray ghost imaging(XGI),the imaging time is a major challenge.In this paper,we propose a fast XGI scheme based on a continuous translation mask with etched aggregate patterns.High contrastto-noise ratio images are obtained with an exposure time of only 4 s and 24 s for a 3.4 mm×3.8 mm and 5.9 mm×6.1 mm field-of-view,respectively.The spatial resolution can reach∼150μm.The influences of the sampling frequency,the mask scanning speed,and the detector integration time on image quality are examined,from which we demonstrate that the imaging time can be further reduced by increasing the mask translation speed.By applying a compressed sensing reconstruction algorithm,the exposure time is greatly reduced while maintaining image quality.Our method indicates a path for the development of future XGI applications.展开更多
X‐ray imaging is foundational and urgent to biomedical diagnosis and industrial nondestructive inspections;however,conventional single‐dose approaches offer limited material specificity.Here,we present a deep learn...X‐ray imaging is foundational and urgent to biomedical diagnosis and industrial nondestructive inspections;however,conventional single‐dose approaches offer limited material specificity.Here,we present a deep learning–driven X‐ray imaging technique leveraging vapor‐deposited multicolor halide scintillation film stacks,enabling imaging and the systematic curation of a materials genome database.By coupling an Attention U‐Net with extreme Gradient Boosting,we further develop an end‐to‐end density regression system that outputs quantitative material information directly from chromatic images,realizing segmentation of circuit‐and pixel‐level mapping from red/green/blue(RGB)values to densities,with an intersection over union of 81%and a root mean square error of±0.622 g cm^(−3).The effectiveness has been demonstrated through segmentation of complex circuit boards and 3D reconstruction of material density distributions.This work delivers a reliable and intelligent material platform and technique for chromatic X‐ray imaging,offering enhanced material discrimination and nondestructive testing capabilities.展开更多
Fourier ptychography(FP)offers both wide field-of-view and high-resolution holographic imaging,making it valuable for applications ranging from microscopy and X-ray imaging to remote sensing.However,its practical impl...Fourier ptychography(FP)offers both wide field-of-view and high-resolution holographic imaging,making it valuable for applications ranging from microscopy and X-ray imaging to remote sensing.However,its practical implementation remains challenging due to the requirement for precise numerical forward models that accurately represent real-world imaging systems.This sensitivity to model-reality mismatches makes FP vulnerable to physical uncertainties,including misalignment,optical element aberrations,and data quality limitations.Conventional approaches address these challenges through separate methods:manual calibration or digital correction for misalignment;pupil or probe reconstruction to mitigate aberrations;or data quality enhancement through exposure adjustments or high dynamic range(HDR)techniques.Critically,these methods cannot simultaneously address the interconnected uncertainties that collectively degrade imaging performance.We introduce Uncertainty-Aware FP(UA-FP),a comprehensive framework that simultaneously addresses multiple system uncertainties without requiring complex calibration and data collection procedures.Our approach develops a fully differentiable forward imaging model that incorporates deterministic uncertainties(misalignment and optical aberrations)as optimizable parameters,while leveraging differentiable optimization with domain-specific priors to address stochastic uncertainties(noise and data quality limitations).Experimental results demonstrate that UA-FP achieves superior reconstruction quality under challenging conditions.The method maintains robust performance with reduced sub-spectrum overlap requirements and retains high-quality reconstructions even with low bit sensor data.Beyond improving image reconstruction,our approach enhances system reconfigurability and extends FP's capabilities as a measurement tool suitable for operation in environments where precise alignment and calibration are impractical.展开更多
In order to verify whether magnetic resonance imaging (MRI) is superior to computed tomography (CT) in the detection and characterization of intrahepatic hematoma in its acute stage, the MRI and CT features of acute t...In order to verify whether magnetic resonance imaging (MRI) is superior to computed tomography (CT) in the detection and characterization of intrahepatic hematoma in its acute stage, the MRI and CT features of acute traumatic hepatic rupture (ATHR) were retrospectively studied and compared. Methods: In the 10 cases of ATHR admitted to our institute, 3 were examined with CT, 1 with MRI and 6 with both CT and MRI in the first 24 hours post injury and 9 cases out of the 10 were checked up with MRI in the first week after injury of surgery. The shape of the traumatic lesions, the damages of the intrahepatic vessels and the severity of hepatic rupture displayed with CT and MRI were compared. Results: It was found that in the first 24 hours post injury, 66.6% of hepatic injuries were shown as hypointensity on T1 weighted images and low or high density on noncontrast CT. 100% of the lesions were identified as well marked hyperintensity on T2 weighted images. Damages of the hepatic and/or portal veins were observed in 7, 4 and 3 cases on T2 and T1 weighted images and noncontrast CT figures respectively. The severity of hepatic injuries were graded in 100%, 66.7% and 44.4%of cases with these 3 procedures respectively. Conclusions: On the basis of our findings, it is concluded that T2 weighted MRI is a more sensitive and reliable imaging modality in the detection and differentiation of the type and severity of acute hepatic rupture than T1 weighted imaging and noncontrast CT.展开更多
基金supported by the CAS Project for Young Scientists in Basic Research(YSBR-096)the National Major Scientific Instruments and Equipment Development Project of China(No.11627901)+1 种基金the National Key Research and Development Program of China(Nos.2021YFF0701202,2021YFA1600703)the National Natural Science Foundation of China(Nos.U1932205,12275343).
文摘The fast X-ray imaging beamline(BL16U2)at Shanghai Synchrotron Radiation Facility(SSRF)is a new beamline that provides X-ray micro-imaging capabilities across a wide range of time scales,spanning from 100 ps toμs and ms.This beamline has been specifically designed to facilitate the investigation of a wide range of rapid phenomena,such as the deformation and failure of materials subjected to intense dynamic loads.In addition,it enables the study of high-pressure and high-speed fuel spray processes in automotive engines.The light source of this beamline is a cryogenic permanent magnet undulator(CPMU)that is cooled by liquid nitrogen.This CPMU can generate X-ray photons within an energy range of 8.7-30 keV.The beamline offers two modes of operation:monochromatic beam mode with a liquid nitrogen-cooled double-crystal monochromator(DCM)and pink beam mode with the first crystal of the DCM out of the beam path.Four X-ray imaging methods were implemented in BL16U2:single-pulse ultrafast X-ray imaging,microsecond-resolved X-ray dynamic imaging,millisecond-resolved X-ray dynamic micro-CT,and high-resolution quantitative micro-CT.Furthermore,BL16U2 is equipped with various in situ impact loading systems,such as a split Hopkinson bar system,light gas gun,and fuel spray chamber.Following the completion of the final commissioning in 2021 and subsequent trial operations in 2022,the beamline has been officially available to users from 2023.
文摘Awell-anticipated wide-field X-ray focusing imager,the Einstein Probe(EP,also named“Tianguan”in Chinese)has caught the eye of astronomers since its launch in January 2024.Initiated and sponsored by the Chinese Academy of Sciences(CAS),and developed in cooperation with the European Space Agency(ESA).
文摘A primary study on Processing in X - ray inspection of spot weld for aluminum alloy spot welding,in- cluding for background simulation,acquisition of ideal binary image, and extraction and identifi- cation of defect features was presented.
基金supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB0530000)the Discipline Construction Foundation of“Double World-class Project”.
文摘Laser wakefield accelerators(LWFAs)offer acceleration gradients up to 1000 times higher than those of conventional radio-frequency accelerators,offering a pathway to significantly more compact and cost-effective accelerator systems.This breakthrough opens up new possibilities for laboratory-scale light sources.All-optical inverse Compton scattering(AOCS)sources driven by LWFAs produce high-brightness,quasimonochromatic X rays with micrometer-scale source sizes,delivering the spatial coherence and resolution required for X-ray phase-contrast imaging(XPCI).These features position AOCS X-ray sources as promising tools for applications in biology,medicine,physics,and materials science.However,previous AOCS-based imaging studies have primarily focused on X-ray absorption imaging.In this work,we report successful experimental demonstrations of edge-enhanced in-line XPCI using energy-tunable,quasi-monochromatic AOCS X rays.With a spatial resolution of~20μm,our results clearly show the potential of high-resolution,AOCS-based XPCI applications.
基金supported in part by the DARPA Agreement No.HO0011249049supported in part by the US Army Research Office through the Institute for Soldier Nanotechnologies at MIT,under Collaborative Agreement Number W911NF-23-2-0121supported by a Stanford Science Fellowship.
文摘Scintillators have been widely used in X-ray imaging due to their ability to convert high-energy radiation into visible light,making them essential for applications such as medical imaging and high-energy physics.Recent advances in the artificial structuring of scintillators offer new opportunities for improving the energy resolution of scintillator-based X-ray detectors.Here,we present a three-bin energy-resolved X-ray imaging framework based on a three-layer multicolor scintillator used in conjunction with a physics-aware image postprocessing algorithm.The multicolor scintillator is able to preserve X-ray energy information through the combination of emission wavelength multiplexing and energy-dependent isolation of X-ray absorption in specific layers.The dominant emission color and the radius of the spot measured by the detector are used to infer the incident X-ray energy based on prior knowledge of the energy-dependent absorption profiles of the scintillator stack.Through ab initio Monte Carlo simulations,we show that our approach can achieve an energy reconstruction accuracy of 49.7%,which is only 2%below the maximum accuracy achievable with realistic scintillators.We apply our framework to medical phantom imaging simulations where we demonstrate that it can effectively differentiate iodine and gadolinium-based contrast agents from bone,muscle,and soft tissue.
基金supported by financial aid from the National Natural Science Foundation of China(22271273).
文摘Lanthanide(Ln)-based metal halides with excellent luminescence properties,large Stokes shifts,and low toxicity have aroused wide attention as scintillators for X-ray imaging.However,the lack of fast and mild synthesis methods of Ln-based metal halides,as one of the technical challenges,limits their applications.Here,benefiting from the innovative selection of methanol and ethanol as the solvent and anti-solvent,respectively,a series of Cs3LnCl6(Ln=Ce,Pr,Nd,Sm,Eu,Gd,Tb,Dy,Ho,Er,Tm,Yb,Lu)microcrystals(MCs)were prepared via the recrystallization method at room temperature for the first time.This recrystallization method could also realize large-scale production at one time and recyclable recrystallization of single-element MCs and the preparation of high-entropy five-element Cs_(3){TbDy-HoErTm}_(1)Cl_(6) crystals.Among these Cs_(3)LnCl_(6)MCs,Cs_(3)TbCl_(6)MCs with 4f→ 5d absorption transition possess the highest photoluminescence quantum yield of 90.8%.Besides,under X-ray irradiation,Cs3TbCl6 MCs show a high light yield of~51,800 photons MeV^(-1) and the as-fabricated thin films possess promising X-ray imaging ability and excellent spatial resolutions(12 Ip mm^(-1)).This work provides a new method for ultrafast preparing Ln-based metal halides under mild synthetic conditions and highlights their excellent potential as scintillators for X-ray imaging.
基金supported by funding from a Canada Excellence Research Chairs(CERC)Grant to L.K.from funding from the Global Institute for Food Security and the University of Saskatchewan,to L.K.
文摘The efficiency of N2-fixation in legume-rhizobia symbiosis is a function of root nodule activity.Nodules consist of 2 functionally important tissues:(a)a central infected zone(CIZ),colonized by rhizobia bacteria,which serves as the site of N2-fixation,and(b)vascular bundles(VBs),serving as conduits for the transport of water,nutrients,and fixed nitrogen compounds between the nodules and plant.A quantitative evaluation of these tissues is essential to unravel their functional importance in N2-fixation.Employing synchrotron-based x-ray microcomputed tomography(SR-μCT)at submicron resolutions,we obtained high-quality tomograms of fresh soybean root nodules in a non-invasive manner.A semi-automated segmentation algorithm was employed to generate 3-dimensional(3D)models of the internal root nodule structure of the CIZ and VBs,and their volumes were quantified based on the reconstructed 3D structures.Furthermore,synchrotron x-ray fluorescence imaging revealed a distinctive localization of Fe within CIZ tissue and Zn within VBs,allowing for their visualization in 2 dimensions.This study represents a pioneer application of the SR-μCT technique for volumetric quantification of CIZ and VB tissues in fresh,intact soybean root nodules.The proposed methods enable the exploitation of root nodule's anatomical features as novel traits in breeding,aiming to enhance N2-fixation through improved root nodule activity.
文摘The Einstein Probe(EP)satellite represents a significant milestone in China's pursuit of advancing time-domain astronomy and high-energy astrophysics.At its core lies the Follow-up X-ray Telescope(FXT),a groundbreaking payload that marks China's first foray into Wolter-I focusing technology for X-ray imaging.Designed with a dual-telescope structure,FXT incorporates 54 layers of ultra-smooth,gold-coated nickel mirror shells nested within each focusing mirror,paired with an advanced PNCCD focal plane detector,coupled with an advanced PNCCD focal plane detector.
基金National Natural Science Foundation of China(61975229,12335016,11991073,W2412039,61805006)National Key R&D Program of China(2018YFB0504302)Strategic Priority Research Program of the CAS(XDA25030400,XDA25010100).
文摘For practical applications of X-ray ghost imaging(XGI),the imaging time is a major challenge.In this paper,we propose a fast XGI scheme based on a continuous translation mask with etched aggregate patterns.High contrastto-noise ratio images are obtained with an exposure time of only 4 s and 24 s for a 3.4 mm×3.8 mm and 5.9 mm×6.1 mm field-of-view,respectively.The spatial resolution can reach∼150μm.The influences of the sampling frequency,the mask scanning speed,and the detector integration time on image quality are examined,from which we demonstrate that the imaging time can be further reduced by increasing the mask translation speed.By applying a compressed sensing reconstruction algorithm,the exposure time is greatly reduced while maintaining image quality.Our method indicates a path for the development of future XGI applications.
基金National Natural Science Foundation of China,Grant/Award Numbers:52425206,52502182,22361132525Fundamental Research Funds for the Central Universities,Grant/Award Number:2024ZYGXZR065+2 种基金Basic and Applied Basic Research Foundation of Guangdong Province,Grant/Award Number:2025A1515010796China Postdoctoral Science Foundation,Grant/Award Number:2025M770201State Key Laboratory of Luminescent Materials and Devices,Grant/Award Number:Skllmd‐2024‐21。
文摘X‐ray imaging is foundational and urgent to biomedical diagnosis and industrial nondestructive inspections;however,conventional single‐dose approaches offer limited material specificity.Here,we present a deep learning–driven X‐ray imaging technique leveraging vapor‐deposited multicolor halide scintillation film stacks,enabling imaging and the systematic curation of a materials genome database.By coupling an Attention U‐Net with extreme Gradient Boosting,we further develop an end‐to‐end density regression system that outputs quantitative material information directly from chromatic images,realizing segmentation of circuit‐and pixel‐level mapping from red/green/blue(RGB)values to densities,with an intersection over union of 81%and a root mean square error of±0.622 g cm^(−3).The effectiveness has been demonstrated through segmentation of complex circuit boards and 3D reconstruction of material density distributions.This work delivers a reliable and intelligent material platform and technique for chromatic X‐ray imaging,offering enhanced material discrimination and nondestructive testing capabilities.
基金supported by the Hong Kong Research Grants Council(GRF 17200321,GRF 17201822)Y.W.and J.W.work was supported by the National Natural Science Foundation of China(62275178).
文摘Fourier ptychography(FP)offers both wide field-of-view and high-resolution holographic imaging,making it valuable for applications ranging from microscopy and X-ray imaging to remote sensing.However,its practical implementation remains challenging due to the requirement for precise numerical forward models that accurately represent real-world imaging systems.This sensitivity to model-reality mismatches makes FP vulnerable to physical uncertainties,including misalignment,optical element aberrations,and data quality limitations.Conventional approaches address these challenges through separate methods:manual calibration or digital correction for misalignment;pupil or probe reconstruction to mitigate aberrations;or data quality enhancement through exposure adjustments or high dynamic range(HDR)techniques.Critically,these methods cannot simultaneously address the interconnected uncertainties that collectively degrade imaging performance.We introduce Uncertainty-Aware FP(UA-FP),a comprehensive framework that simultaneously addresses multiple system uncertainties without requiring complex calibration and data collection procedures.Our approach develops a fully differentiable forward imaging model that incorporates deterministic uncertainties(misalignment and optical aberrations)as optimizable parameters,while leveraging differentiable optimization with domain-specific priors to address stochastic uncertainties(noise and data quality limitations).Experimental results demonstrate that UA-FP achieves superior reconstruction quality under challenging conditions.The method maintains robust performance with reduced sub-spectrum overlap requirements and retains high-quality reconstructions even with low bit sensor data.Beyond improving image reconstruction,our approach enhances system reconfigurability and extends FP's capabilities as a measurement tool suitable for operation in environments where precise alignment and calibration are impractical.
文摘In order to verify whether magnetic resonance imaging (MRI) is superior to computed tomography (CT) in the detection and characterization of intrahepatic hematoma in its acute stage, the MRI and CT features of acute traumatic hepatic rupture (ATHR) were retrospectively studied and compared. Methods: In the 10 cases of ATHR admitted to our institute, 3 were examined with CT, 1 with MRI and 6 with both CT and MRI in the first 24 hours post injury and 9 cases out of the 10 were checked up with MRI in the first week after injury of surgery. The shape of the traumatic lesions, the damages of the intrahepatic vessels and the severity of hepatic rupture displayed with CT and MRI were compared. Results: It was found that in the first 24 hours post injury, 66.6% of hepatic injuries were shown as hypointensity on T1 weighted images and low or high density on noncontrast CT. 100% of the lesions were identified as well marked hyperintensity on T2 weighted images. Damages of the hepatic and/or portal veins were observed in 7, 4 and 3 cases on T2 and T1 weighted images and noncontrast CT figures respectively. The severity of hepatic injuries were graded in 100%, 66.7% and 44.4%of cases with these 3 procedures respectively. Conclusions: On the basis of our findings, it is concluded that T2 weighted MRI is a more sensitive and reliable imaging modality in the detection and differentiation of the type and severity of acute hepatic rupture than T1 weighted imaging and noncontrast CT.
