“We are together.We are friends forever.Nothing can break the bond between you and me,”On December 30,2025,these heartfelt lyrics,sung in both Chinese and English,filled the historic Erqi Theater in central Beijing....“We are together.We are friends forever.Nothing can break the bond between you and me,”On December 30,2025,these heartfelt lyrics,sung in both Chinese and English,filled the historic Erqi Theater in central Beijing.Theywere performed by 54 young vocalists from the One Voice Children’s Choir of Utah,U.S.,joined on stage by a dozen students from the High School Affiliated to Xi’an Jiaotong University.Ranging in age from five to 18,the choir delivered a spectacular performance that visibly captivated the audience.展开更多
As profound changes unseen in a century unfold at a faster pace,the world economy enters into a new phase of turbulence and transformation.Under the continuous impact of multiple shocks,the world economy is recovering...As profound changes unseen in a century unfold at a faster pace,the world economy enters into a new phase of turbulence and transformation.Under the continuous impact of multiple shocks,the world economy is recovering amidst twists and turns,with insufficient growth momentum and diverging development trends.Meanwhile,profound structural changes are reshaping the global economic landscape.A new round of technological revolution and industrial transformation,most notably the explosive development of disruptive technologies such as Artificial Intelligence(AI),is generating new industries,business models,and drivers of growth,while exerting far-reaching influence on the global division of labor,employment structures,and even international norms.展开更多
The World Journal of Gastroenterology Editorial Board Members are composed of 357 distinguished experts active in the relevant field,distributed in 46 countries/regions,including Italy(66),Japan(53),United States(31),...The World Journal of Gastroenterology Editorial Board Members are composed of 357 distinguished experts active in the relevant field,distributed in 46 countries/regions,including Italy(66),Japan(53),United States(31),China(29),South Korea(16),Spain(15),Australia(13),Greece(12),Brazil(11),Romania(8),Germany(7),India(7),Taiwan(7),United Kingdom(7),Türkiye(7),Hungary(5),Russia(5).展开更多
In an age of global challenges,there are numerous issues whose solutions require closer international cooperation.THE world is passing through another era of profound uncertainty.Many had assumed that the age of globa...In an age of global challenges,there are numerous issues whose solutions require closer international cooperation.THE world is passing through another era of profound uncertainty.Many had assumed that the age of global crises,wars,and geopolitical tensions was behind us,and that humanity had moved beyond a time when armed conflicts in some parts of the world could dictate the rhythms of daily life.The events of recent years,however,have made it clear that history,in the sense of hegemonism and largescale confrontation,has not been consigned to the past.展开更多
The 23rd World Congress of Soil Science(23rd WCSS),to be held on June 7-12,2026 in Nanjing,China,marks a historic coming of this century-old scientific gathering to one of the world's ancient agricultural civiliza...The 23rd World Congress of Soil Science(23rd WCSS),to be held on June 7-12,2026 in Nanjing,China,marks a historic coming of this century-old scientific gathering to one of the world's ancient agricultural civilizations.Since its inception in1927,this will be the first time the Congress is hosted in China,a land whose agricultural resilience has been nurtured by millennia of soil stewardship.展开更多
China provides a compelling reference for how governments can promote global climate governance and sustainable innovative development.SENIOR government officials,technical experts,and policy researchers from 14 devel...China provides a compelling reference for how governments can promote global climate governance and sustainable innovative development.SENIOR government officials,technical experts,and policy researchers from 14 developing countries in Asia,Africa,Latin America,and Pacific Island countries gathered at Tsinghua University(THU),Beijing,on September 1-13,2025 for in-depth study and exchange on“climate finance and low-carbon transformation.”展开更多
The annual meetings of the 14th National People’s Congress(NPC)and the 14th National Committee of the Chinese People’s Political Consultative Conference(CPPCC),known as the Two Sessions,were held in Beijing in March...The annual meetings of the 14th National People’s Congress(NPC)and the 14th National Committee of the Chinese People’s Political Consultative Conference(CPPCC),known as the Two Sessions,were held in Beijing in March.Thousands of NPC deputies and CPPCC National Committee members from different regions and walks of life discussed national policies,economic plans and developmental goals.展开更多
Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of mineral...Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of minerals,with reserves of at least 38 of over 80 widely used minerals worldwide accounting for more than30%of the global total reserves.Asia continent experienced three main tectonic evolution and mineralization stages:The Precambrian,the Paleozoic,and the Mesozoic to Cenozoic.The abundant mineral resources in this continent can be divided into seven first-order metallogenic belts(metallogenic domains),18 second-order metallogenic belts(metallogenic provinces),61 third-order metallogenic belts(metallogenic zones),and nine main minerogenetic series.Asia continent exhibits the most significant metallogenic specialization among all continents.Specifically,granite belts of Asia continent manifest pronounced metallogenic specialization of tin,rare metals,and porphyry Cu-Au-Mo deposits.Its maficultramafic rock belts and ophiolite belts display notable metallogenic specialization of lateritic nickel deposits and magmatic type chromite deposits,while its Mesozoic to Cenozoic basalt belts show remarkable metallogenic specialization of lateritic bauxite deposits.Consequently,many giant metallogenic belts were formed,including the Southeast Asian tin belt,the Qinghai-Xizang Plateau rare metal metallogenic belt,the Tethyan porphyry Cu-Au-Mo metallogenic belt,the circum-Pacific porphyry Cu-Au-Mo metallogenic belt,the Southeast Asian lateritic bauxite metallogenic belt,the Deccan Plateau lateritic bauxite metallogenic belt in India,the Southeast Asian lateritic nickel metallogenic belt,and the Tethyan magmatic type chromite metallogenic belt—all of which are significant metallogenic belts in Asia continent.Future mineral exploration in Asia should focus primarily on the Precambrian mineralization of ancient cratons,the Paleozoic mineralization of the Central Asian-Mongolian orogenic belt,and the Mesozoic to Cenozoic mineralization of the Tethyan and circum-Pacific mobile belts.Asia's mining industry not only underpins its own economic growth but also propels global economic development and industrialization,contributing significantly to the world economy.Asia boasts the highest production value of minerals,the largest annual production of minerals,and the greatest trade value of mineral products among all the continents,having emerged as the trade center of global mineral products and the center of the mining industry economy.China is identified as one of the few countries that possess the most comprehensive kinds of minerals,and its mining industry has supported and driven the economic development and industrialization of Asia and even the world.Standing as the largest mineral producer worldwide,China ranked first in the production of 28 mineral commodities in the world in 2022.Besides,China exhibits the highest annual production value of minerals and the largest trade value of mineral products among all countries.Therefore,China's demand for global mineral products influences the global supply and demand patterns of minerals and the world economic situation.展开更多
In June 2026,the FIFA World Cup will be jointly hosted by three countries for the first time,featur ing 48 teams and 104 matches across 16 cities in North Amer ica.For the United States,Canada,and Mexico,this is not o...In June 2026,the FIFA World Cup will be jointly hosted by three countries for the first time,featur ing 48 teams and 104 matches across 16 cities in North Amer ica.For the United States,Canada,and Mexico,this is not only a sporting event but also a well-planned“economic feast.”展开更多
The World Standards Day(WSD),the big day of global standardizers,is celebrated annually on October 14.Themed“Shared vision for a better world:Spotlight on SDG 17—Partnership for the goals”,this year’s WSD places g...The World Standards Day(WSD),the big day of global standardizers,is celebrated annually on October 14.Themed“Shared vision for a better world:Spotlight on SDG 17—Partnership for the goals”,this year’s WSD places greater emphasis on joint efforts and cooperation for SDGs.展开更多
Focusing on“Shared vision for a better world:Spotlight on SDG 17—Partnership for the goals”,the themed event of World Standards Day 2025 was held on October 14 in Beijing.Presided over by Xiao Han,Director-General ...Focusing on“Shared vision for a better world:Spotlight on SDG 17—Partnership for the goals”,the themed event of World Standards Day 2025 was held on October 14 in Beijing.Presided over by Xiao Han,Director-General of Standards Innovative Department of SAMR,the event was attended by Deng Zhiyong,Vice Minister of SAMR and Administrator of SAC,and addressed by Sergio Mujica,ISO Secretary-General,and Jo Cops,IEC President,via videos.展开更多
From 9th to 10th July,the Eleventh Nishan Forum on World Civilisation was held in Nishan,Qufu,Shandong Province,the birthplace of Confucius.This year's forum,themed"Our Diverse World,Our Shared Values-Civilis...From 9th to 10th July,the Eleventh Nishan Forum on World Civilisation was held in Nishan,Qufu,Shandong Province,the birthplace of Confucius.This year's forum,themed"Our Diverse World,Our Shared Values-Civilisational Relationships and Global Modernisation".展开更多
The World Telecommunication Development Conference 2025(WTDC-25)will be hosted by the Government of Azerbaijan in Baku on November 17-28,2025.World Telecommunication Development Conferences(WTDCs)are convened in the p...The World Telecommunication Development Conference 2025(WTDC-25)will be hosted by the Government of Azerbaijan in Baku on November 17-28,2025.World Telecommunication Development Conferences(WTDCs)are convened in the period between two Plenipotentiary Conferences to consider topics,projects and programmes relevant to telecommunication development.WTDCs set the strategies and objectives for the development of telecommunication/ICT,providing direction and guidance to the ITU Telecommunication Development Sector(ITU-D).展开更多
The successful application of the Xixia Imperial Tombs for World Heritage Status has brought this civilization,sealed in the loess,to the global stage.The Xixia Imperial Tombs may become an important node connecting t...The successful application of the Xixia Imperial Tombs for World Heritage Status has brought this civilization,sealed in the loess,to the global stage.The Xixia Imperial Tombs may become an important node connecting the civilizations along the Silk Road.Their characteristic cultural integration serves as a unique window through which foreign tourists can understand Chinese civilization.展开更多
On July 9,the launch conference of World Energy Investment Report 2025 was held at Peking University.This conference was co-hosted by the International Energy Agency(IEA)and the Institute of Energy,Peking University a...On July 9,the launch conference of World Energy Investment Report 2025 was held at Peking University.This conference was co-hosted by the International Energy Agency(IEA)and the Institute of Energy,Peking University and the Energy Foundation.Xu Li,First-level Researcher at the Second Division of International Financial Organizations under the Department of International Financial Cooperation of the Ministry of Finance and direct leader of the Ministry of Finance International Financial Research Expert Workshop,Tim Gould,Chief Energy Economist of the International Energy Agency(IEA),and Mr.Zhang Huiyong,Executive Director of International Cooperation at the Energy Foundation,attended the opening ceremony and delivered speeches.Yang Lei,Associate Dean of the Institute of Energy,Peking University,chaired the press conference.展开更多
On the basis of research evaluation of Chinese universities,Golden Apple Ranking(GAR)was initiated by Research Center of Chinese Science Evaluation(RCCSE)at Wuhan University in 2003.The GAR consists of four major rank...On the basis of research evaluation of Chinese universities,Golden Apple Ranking(GAR)was initiated by Research Center of Chinese Science Evaluation(RCCSE)at Wuhan University in 2003.The GAR consists of four major rankings:Chinese University Ranking,Chinese Graduate School Ranking,World University Ranking and Scholarly Journal Ranking.The annual reports of all these four rankings are published bythe Science Press,which have been recognized by the academia and China's government.展开更多
Objective Rheumatoid arthritis(RA)is a systemic autoimmune disease that affects the small joints of the whole body and degrades the patients’quality of life.Zhengqing Fengtongning(ZF)is a traditional Chinese medicine...Objective Rheumatoid arthritis(RA)is a systemic autoimmune disease that affects the small joints of the whole body and degrades the patients’quality of life.Zhengqing Fengtongning(ZF)is a traditional Chinese medicine preparation used to treat RA.ZF may cause liver injury.In this study,we aimed to develop a prediction model for abnormal liver function caused by ZF.Methods This retrospective study collected data from multiple centers from January 2018 to April 2023.Abnormal liver function was set as the target variable according to the alanine transaminase(ALT)level.Features were screened through univariate analysis and sequential forward selection for modeling.Ten machine learning and deep learning models were compared to find the model that most effectively predicted liver function from the available data.Results This study included 1,913 eligible patients.The LightGBM model exhibited the best performance(accuracy=0.96)out of the 10 learning models.The predictive metrics of the LightGBM model were as follows:precision=0.99,recall rate=0.97,F1_score=0.98,area under the curve(AUC)=0.98,sensitivity=0.97 and specificity=0.85 for predicting ALT<40 U/L;precision=0.60,recall rate=0.83,F1_score=0.70,AUC=0.98,sensitivity=0.83 and specificity=0.97 for predicting 40≤ALT<80 U/L;and precision=0.83,recall rate=0.63,F1_score=0.71,AUC=0.97,sensitivity=0.63 and specificity=1.00 for predicting ALT≥80 U/L.ZF-induced abnormal liver function was found to be associated with high total cholesterol and triglyceride levels,the combination of TNF-αinhibitors,JAK inhibitors,methotrexate+nonsteroidal anti-inflammatory drugs,leflunomide,smoking,older age,and females in middle-age(45-65 years old).Conclusion This study developed a model for predicting ZF-induced abnormal liver function,which may help improve the safety of integrated administration of ZF and Western medicine.展开更多
Diffuse large B-cell lymphoma(DLBCL),the most common subtype of non-Hodgkin’s lymphoma(NHL)worldwide,accounts for 39% and 44% of nodal and extranodal NHL cases in China,respectively1.Standard first-line treatment for...Diffuse large B-cell lymphoma(DLBCL),the most common subtype of non-Hodgkin’s lymphoma(NHL)worldwide,accounts for 39% and 44% of nodal and extranodal NHL cases in China,respectively1.Standard first-line treatment for DLBCL is chemo-immunotherapy with rituximab,cyclophos-phamide,doxorubicin,vincristine,and prednisone,which cures 50%-60% of patients2.展开更多
“Multidimensional international world”refers to understanding the world through multiple dimensions beyond traditional economic or political measures,fostering cross-cultural collaboration,and creating systems that ...“Multidimensional international world”refers to understanding the world through multiple dimensions beyond traditional economic or political measures,fostering cross-cultural collaboration,and creating systems that balance global integration with local needs.This also includes management of global business operations across diverse cultures in a multipolar international landscape.The paper briefs the developed and already tested in numerous applications high-level Spatial Grasp Model and Technology(SGT),which can help investigate and manage complex systems with a holistic spatial approach effectively covering various physical and virtual dimensions,their interrelations,and integration as a whole.Different areas will be investigated with examples of practical solutions in them and their combinations in a high-level Spatial Grasp Language(SGL),the key element of SGT.This allows for the creation and distributed management of very large spatial networks with different orientation which can be self-spreading,self-analyzing,self-modifying,and self-recovering in complex terrestrial and celestial environments,and also organize dynamic multi-networking solutions supporting global evolution and integrity.展开更多
文摘“We are together.We are friends forever.Nothing can break the bond between you and me,”On December 30,2025,these heartfelt lyrics,sung in both Chinese and English,filled the historic Erqi Theater in central Beijing.Theywere performed by 54 young vocalists from the One Voice Children’s Choir of Utah,U.S.,joined on stage by a dozen students from the High School Affiliated to Xi’an Jiaotong University.Ranging in age from five to 18,the choir delivered a spectacular performance that visibly captivated the audience.
文摘As profound changes unseen in a century unfold at a faster pace,the world economy enters into a new phase of turbulence and transformation.Under the continuous impact of multiple shocks,the world economy is recovering amidst twists and turns,with insufficient growth momentum and diverging development trends.Meanwhile,profound structural changes are reshaping the global economic landscape.A new round of technological revolution and industrial transformation,most notably the explosive development of disruptive technologies such as Artificial Intelligence(AI),is generating new industries,business models,and drivers of growth,while exerting far-reaching influence on the global division of labor,employment structures,and even international norms.
文摘The World Journal of Gastroenterology Editorial Board Members are composed of 357 distinguished experts active in the relevant field,distributed in 46 countries/regions,including Italy(66),Japan(53),United States(31),China(29),South Korea(16),Spain(15),Australia(13),Greece(12),Brazil(11),Romania(8),Germany(7),India(7),Taiwan(7),United Kingdom(7),Türkiye(7),Hungary(5),Russia(5).
文摘In an age of global challenges,there are numerous issues whose solutions require closer international cooperation.THE world is passing through another era of profound uncertainty.Many had assumed that the age of global crises,wars,and geopolitical tensions was behind us,and that humanity had moved beyond a time when armed conflicts in some parts of the world could dictate the rhythms of daily life.The events of recent years,however,have made it clear that history,in the sense of hegemonism and largescale confrontation,has not been consigned to the past.
文摘The 23rd World Congress of Soil Science(23rd WCSS),to be held on June 7-12,2026 in Nanjing,China,marks a historic coming of this century-old scientific gathering to one of the world's ancient agricultural civilizations.Since its inception in1927,this will be the first time the Congress is hosted in China,a land whose agricultural resilience has been nurtured by millennia of soil stewardship.
文摘China provides a compelling reference for how governments can promote global climate governance and sustainable innovative development.SENIOR government officials,technical experts,and policy researchers from 14 developing countries in Asia,Africa,Latin America,and Pacific Island countries gathered at Tsinghua University(THU),Beijing,on September 1-13,2025 for in-depth study and exchange on“climate finance and low-carbon transformation.”
文摘The annual meetings of the 14th National People’s Congress(NPC)and the 14th National Committee of the Chinese People’s Political Consultative Conference(CPPCC),known as the Two Sessions,were held in Beijing in March.Thousands of NPC deputies and CPPCC National Committee members from different regions and walks of life discussed national policies,economic plans and developmental goals.
基金funded by geological survey project of China Geological Survey(DD20211404)。
文摘Mineral resources in Asia continent and its mining industry play a significant role in the economic growth and industrialization of both Asia and the world.Asia continent boasts the most comprehensive kinds of minerals,with reserves of at least 38 of over 80 widely used minerals worldwide accounting for more than30%of the global total reserves.Asia continent experienced three main tectonic evolution and mineralization stages:The Precambrian,the Paleozoic,and the Mesozoic to Cenozoic.The abundant mineral resources in this continent can be divided into seven first-order metallogenic belts(metallogenic domains),18 second-order metallogenic belts(metallogenic provinces),61 third-order metallogenic belts(metallogenic zones),and nine main minerogenetic series.Asia continent exhibits the most significant metallogenic specialization among all continents.Specifically,granite belts of Asia continent manifest pronounced metallogenic specialization of tin,rare metals,and porphyry Cu-Au-Mo deposits.Its maficultramafic rock belts and ophiolite belts display notable metallogenic specialization of lateritic nickel deposits and magmatic type chromite deposits,while its Mesozoic to Cenozoic basalt belts show remarkable metallogenic specialization of lateritic bauxite deposits.Consequently,many giant metallogenic belts were formed,including the Southeast Asian tin belt,the Qinghai-Xizang Plateau rare metal metallogenic belt,the Tethyan porphyry Cu-Au-Mo metallogenic belt,the circum-Pacific porphyry Cu-Au-Mo metallogenic belt,the Southeast Asian lateritic bauxite metallogenic belt,the Deccan Plateau lateritic bauxite metallogenic belt in India,the Southeast Asian lateritic nickel metallogenic belt,and the Tethyan magmatic type chromite metallogenic belt—all of which are significant metallogenic belts in Asia continent.Future mineral exploration in Asia should focus primarily on the Precambrian mineralization of ancient cratons,the Paleozoic mineralization of the Central Asian-Mongolian orogenic belt,and the Mesozoic to Cenozoic mineralization of the Tethyan and circum-Pacific mobile belts.Asia's mining industry not only underpins its own economic growth but also propels global economic development and industrialization,contributing significantly to the world economy.Asia boasts the highest production value of minerals,the largest annual production of minerals,and the greatest trade value of mineral products among all the continents,having emerged as the trade center of global mineral products and the center of the mining industry economy.China is identified as one of the few countries that possess the most comprehensive kinds of minerals,and its mining industry has supported and driven the economic development and industrialization of Asia and even the world.Standing as the largest mineral producer worldwide,China ranked first in the production of 28 mineral commodities in the world in 2022.Besides,China exhibits the highest annual production value of minerals and the largest trade value of mineral products among all countries.Therefore,China's demand for global mineral products influences the global supply and demand patterns of minerals and the world economic situation.
文摘In June 2026,the FIFA World Cup will be jointly hosted by three countries for the first time,featur ing 48 teams and 104 matches across 16 cities in North Amer ica.For the United States,Canada,and Mexico,this is not only a sporting event but also a well-planned“economic feast.”
文摘The World Standards Day(WSD),the big day of global standardizers,is celebrated annually on October 14.Themed“Shared vision for a better world:Spotlight on SDG 17—Partnership for the goals”,this year’s WSD places greater emphasis on joint efforts and cooperation for SDGs.
文摘Focusing on“Shared vision for a better world:Spotlight on SDG 17—Partnership for the goals”,the themed event of World Standards Day 2025 was held on October 14 in Beijing.Presided over by Xiao Han,Director-General of Standards Innovative Department of SAMR,the event was attended by Deng Zhiyong,Vice Minister of SAMR and Administrator of SAC,and addressed by Sergio Mujica,ISO Secretary-General,and Jo Cops,IEC President,via videos.
文摘From 9th to 10th July,the Eleventh Nishan Forum on World Civilisation was held in Nishan,Qufu,Shandong Province,the birthplace of Confucius.This year's forum,themed"Our Diverse World,Our Shared Values-Civilisational Relationships and Global Modernisation".
文摘The World Telecommunication Development Conference 2025(WTDC-25)will be hosted by the Government of Azerbaijan in Baku on November 17-28,2025.World Telecommunication Development Conferences(WTDCs)are convened in the period between two Plenipotentiary Conferences to consider topics,projects and programmes relevant to telecommunication development.WTDCs set the strategies and objectives for the development of telecommunication/ICT,providing direction and guidance to the ITU Telecommunication Development Sector(ITU-D).
文摘The successful application of the Xixia Imperial Tombs for World Heritage Status has brought this civilization,sealed in the loess,to the global stage.The Xixia Imperial Tombs may become an important node connecting the civilizations along the Silk Road.Their characteristic cultural integration serves as a unique window through which foreign tourists can understand Chinese civilization.
文摘On July 9,the launch conference of World Energy Investment Report 2025 was held at Peking University.This conference was co-hosted by the International Energy Agency(IEA)and the Institute of Energy,Peking University and the Energy Foundation.Xu Li,First-level Researcher at the Second Division of International Financial Organizations under the Department of International Financial Cooperation of the Ministry of Finance and direct leader of the Ministry of Finance International Financial Research Expert Workshop,Tim Gould,Chief Energy Economist of the International Energy Agency(IEA),and Mr.Zhang Huiyong,Executive Director of International Cooperation at the Energy Foundation,attended the opening ceremony and delivered speeches.Yang Lei,Associate Dean of the Institute of Energy,Peking University,chaired the press conference.
文摘On the basis of research evaluation of Chinese universities,Golden Apple Ranking(GAR)was initiated by Research Center of Chinese Science Evaluation(RCCSE)at Wuhan University in 2003.The GAR consists of four major rankings:Chinese University Ranking,Chinese Graduate School Ranking,World University Ranking and Scholarly Journal Ranking.The annual reports of all these four rankings are published bythe Science Press,which have been recognized by the academia and China's government.
基金supported by the Budgeted Fund of Shanghai University of Traditional Chinese Medicine(Natural Science)(No.2021LK037)the Open Project of Qinghai Province Key Laboratory of Tibetan Medicine Pharmacology and Safety Evaluation(No.2021-ZY-03).
文摘Objective Rheumatoid arthritis(RA)is a systemic autoimmune disease that affects the small joints of the whole body and degrades the patients’quality of life.Zhengqing Fengtongning(ZF)is a traditional Chinese medicine preparation used to treat RA.ZF may cause liver injury.In this study,we aimed to develop a prediction model for abnormal liver function caused by ZF.Methods This retrospective study collected data from multiple centers from January 2018 to April 2023.Abnormal liver function was set as the target variable according to the alanine transaminase(ALT)level.Features were screened through univariate analysis and sequential forward selection for modeling.Ten machine learning and deep learning models were compared to find the model that most effectively predicted liver function from the available data.Results This study included 1,913 eligible patients.The LightGBM model exhibited the best performance(accuracy=0.96)out of the 10 learning models.The predictive metrics of the LightGBM model were as follows:precision=0.99,recall rate=0.97,F1_score=0.98,area under the curve(AUC)=0.98,sensitivity=0.97 and specificity=0.85 for predicting ALT<40 U/L;precision=0.60,recall rate=0.83,F1_score=0.70,AUC=0.98,sensitivity=0.83 and specificity=0.97 for predicting 40≤ALT<80 U/L;and precision=0.83,recall rate=0.63,F1_score=0.71,AUC=0.97,sensitivity=0.63 and specificity=1.00 for predicting ALT≥80 U/L.ZF-induced abnormal liver function was found to be associated with high total cholesterol and triglyceride levels,the combination of TNF-αinhibitors,JAK inhibitors,methotrexate+nonsteroidal anti-inflammatory drugs,leflunomide,smoking,older age,and females in middle-age(45-65 years old).Conclusion This study developed a model for predicting ZF-induced abnormal liver function,which may help improve the safety of integrated administration of ZF and Western medicine.
基金sponsored by Shanghai Roche Pharmaceuticals Ltd.
文摘Diffuse large B-cell lymphoma(DLBCL),the most common subtype of non-Hodgkin’s lymphoma(NHL)worldwide,accounts for 39% and 44% of nodal and extranodal NHL cases in China,respectively1.Standard first-line treatment for DLBCL is chemo-immunotherapy with rituximab,cyclophos-phamide,doxorubicin,vincristine,and prednisone,which cures 50%-60% of patients2.
文摘“Multidimensional international world”refers to understanding the world through multiple dimensions beyond traditional economic or political measures,fostering cross-cultural collaboration,and creating systems that balance global integration with local needs.This also includes management of global business operations across diverse cultures in a multipolar international landscape.The paper briefs the developed and already tested in numerous applications high-level Spatial Grasp Model and Technology(SGT),which can help investigate and manage complex systems with a holistic spatial approach effectively covering various physical and virtual dimensions,their interrelations,and integration as a whole.Different areas will be investigated with examples of practical solutions in them and their combinations in a high-level Spatial Grasp Language(SGL),the key element of SGT.This allows for the creation and distributed management of very large spatial networks with different orientation which can be self-spreading,self-analyzing,self-modifying,and self-recovering in complex terrestrial and celestial environments,and also organize dynamic multi-networking solutions supporting global evolution and integrity.
