[ Objective ] The insecticidal and antibacterial bioactivity of Wikstroemia chamaedaphne Meissn were screened and bioactive substances in it were separated and purified. [ Method] The Wikstroemia chamaedaphne Meissn w...[ Objective ] The insecticidal and antibacterial bioactivity of Wikstroemia chamaedaphne Meissn were screened and bioactive substances in it were separated and purified. [ Method] The Wikstroemia chamaedaphne Meissn was conducted ultrasonic extraction in petroleum ether, ethyl acetate and methanol. The insecticidal activity of Wikstroemia chamaedaphne Meissn to Mythimna separata walker and aphid were determined. The antibacterial activity of Wikstroemia chamaedaphne Meissn to Fusarium graminearu, Glomerella cingulata, F. oxysporium f. sp niveum, Alternaria solani and Fusarium oxysporium were also determined. The bioactivity-guided methods such as opencolumn chromatography and Pre-HPLC method were used to separate active components in petroleum ether extract from Wikstroemia chamaedaphne Meissn. [ Result] When the concentration was 500 mg/L, 3 kinds of extracts from Wikstroemia chamaedaphne Meissn didn＇ t show obvious antibacterial bioactivity to 5 kinds of test samples. When the concentration was 5%, petroleum ether extract show certain topical toxicity to aphids. The ethyl acetate extract showed certain antifeedant activity to 3^rd instar Larvae of Mythimna separata Walker. The fraction F4 of petroleum ether extract possessed highest topical toxicity to aphids and the lethality was 60.00%. [ Conclusion] Wikstroemia chamaedaphne Meissn contained many insecticidal constituents whose active parts and mechanism were needed further researches.展开更多
A new coumarin was obtained from the stems and roots of Wikstroemia indica （L.） C. A. Mey. Its structure was elucidated as methyl 3-（2-hydroxy-4-（7-hydroxy-6-methoxy-2-oxo-2H-chromen-3-yloxy） phenyl） propanoate ...A new coumarin was obtained from the stems and roots of Wikstroemia indica （L.） C. A. Mey. Its structure was elucidated as methyl 3-（2-hydroxy-4-（7-hydroxy-6-methoxy-2-oxo-2H-chromen-3-yloxy） phenyl） propanoate by spectroscopic methods.展开更多
Both Edgeworthia and Wikstroemia have been used traditionally in hand papermaking in China.As plants from the Thymelaeaceae family,these species have been mentioned periodically and have been mixed or substituted with...Both Edgeworthia and Wikstroemia have been used traditionally in hand papermaking in China.As plants from the Thymelaeaceae family,these species have been mentioned periodically and have been mixed or substituted with each other.This study reviewed their papermaking background and status,and selected one of the Edgeworthia and three of the Wikstroemia raw materials that are still in use.Pulp was cooked under the same conditions in the laboratory,and handsheets of pure and mixed materials were obtained using a Rapid-Köthen sheet former.A series of physical properties,such as color,structure,and mechanical properties were tested,followed by a comparison and discussion of the raw material properties.The results show that Wikstroemia fibers are generally thinner and shorter,but there are variations between the different genera of raw materials.Thus,compared with Edgeworthia,Wikstroemia has some advantages in tensile strength,although it shows some disadvantages when it comes to tearing strength.The performance of a mixed-ingredient paper sheet falls between the performance of two pure-component papers.For cost and performance reasons,adding a small amount of Wikstroemia(e.g.,<20%)to Edgeworthia is preferable.展开更多
Wiksroemia indica belongs to the family of Thymelaeaceae.As a material of Traditional Chinese Medicine,it is mainly used to treat inflammation-related diseases.However,due to its complex composition,the scientific bas...Wiksroemia indica belongs to the family of Thymelaeaceae.As a material of Traditional Chinese Medicine,it is mainly used to treat inflammation-related diseases.However,due to its complex composition,the scientific basis for its traditional application is still insufficient and the mechanism of action is still unclear.At present,most studies on its anti-inflammatory effect focus on a certain component and its different solvent fractions.There are few reports about the synergistic mechanism of the constituents from W.indica for the treatment of inflammatory diseases.Therefore,the present study aimed to uncover its potential mechanism from a holistic perspective using the network pharmacology approach.Firstly,compounds in W.indica and genes associated with inflammatory diseases were obtained.Then,the active compounds were screened out and their targets were predicted.After that,the key targets for W.indica to treat inflammatory diseases were screened out.Finally,the protein-protein interaction(PPI),Gene ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses of key targets were performed to further study the mechanism of W.indica in the treatment of inflammatory diseases.The results showed that the active constituents of W.indica might play an anti-inflammatory role through the key targets CYP19A1 and CYP1B1,which clarified the primary mechanism for the treatment of inflammatory diseases and provided a scientific basis for further study of this herb.展开更多
A new guaiane-type sesquiterpene, wiksphyllamin A （1） with C-10 and C-11 connected, along with fifteen known compounds were isolated from the stems of Wiks＇troemia scytophylla Diels. All these compounds were iso- l...A new guaiane-type sesquiterpene, wiksphyllamin A （1） with C-10 and C-11 connected, along with fifteen known compounds were isolated from the stems of Wiks＇troemia scytophylla Diels. All these compounds were iso- lated for the first time from Wikstroemia scytophylla. The structures of 1--16 were identified using spectroscopic methods.展开更多
Wikstroemia chamedaphne was investigated for its acarocidal activity against Tetranychus viennensis, a serious pest of many crops including apple trees in China. Its active constitutes were extracted,separated and pur...Wikstroemia chamedaphne was investigated for its acarocidal activity against Tetranychus viennensis, a serious pest of many crops including apple trees in China. Its active constitutes were extracted,separated and purified. The results indicated that the extraction of petroleum ether from WCME （Wikstroemia chamaedaphne methanol extract） appeared a strong acarocidal activity. The adjusted mortalities of egg,larva and female mite were 74.48%,100.00% and 100.00% respectively, while the LC50 values were 2.106 2、0.304 1 and 0.771 6 mg·mL-1 respectively.展开更多
基金Supported by School Project of Yan’an University (YD2005-042)~~
文摘[ Objective ] The insecticidal and antibacterial bioactivity of Wikstroemia chamaedaphne Meissn were screened and bioactive substances in it were separated and purified. [ Method] The Wikstroemia chamaedaphne Meissn was conducted ultrasonic extraction in petroleum ether, ethyl acetate and methanol. The insecticidal activity of Wikstroemia chamaedaphne Meissn to Mythimna separata walker and aphid were determined. The antibacterial activity of Wikstroemia chamaedaphne Meissn to Fusarium graminearu, Glomerella cingulata, F. oxysporium f. sp niveum, Alternaria solani and Fusarium oxysporium were also determined. The bioactivity-guided methods such as opencolumn chromatography and Pre-HPLC method were used to separate active components in petroleum ether extract from Wikstroemia chamaedaphne Meissn. [ Result] When the concentration was 500 mg/L, 3 kinds of extracts from Wikstroemia chamaedaphne Meissn didn＇ t show obvious antibacterial bioactivity to 5 kinds of test samples. When the concentration was 5%, petroleum ether extract show certain topical toxicity to aphids. The ethyl acetate extract showed certain antifeedant activity to 3^rd instar Larvae of Mythimna separata Walker. The fraction F4 of petroleum ether extract possessed highest topical toxicity to aphids and the lethality was 60.00%. [ Conclusion] Wikstroemia chamaedaphne Meissn contained many insecticidal constituents whose active parts and mechanism were needed further researches.
文摘A new coumarin was obtained from the stems and roots of Wikstroemia indica （L.） C. A. Mey. Its structure was elucidated as methyl 3-（2-hydroxy-4-（7-hydroxy-6-methoxy-2-oxo-2H-chromen-3-yloxy） phenyl） propanoate by spectroscopic methods.
基金supported by the National Key R&D Program of China(2019YFC1520300).
文摘Both Edgeworthia and Wikstroemia have been used traditionally in hand papermaking in China.As plants from the Thymelaeaceae family,these species have been mentioned periodically and have been mixed or substituted with each other.This study reviewed their papermaking background and status,and selected one of the Edgeworthia and three of the Wikstroemia raw materials that are still in use.Pulp was cooked under the same conditions in the laboratory,and handsheets of pure and mixed materials were obtained using a Rapid-Köthen sheet former.A series of physical properties,such as color,structure,and mechanical properties were tested,followed by a comparison and discussion of the raw material properties.The results show that Wikstroemia fibers are generally thinner and shorter,but there are variations between the different genera of raw materials.Thus,compared with Edgeworthia,Wikstroemia has some advantages in tensile strength,although it shows some disadvantages when it comes to tearing strength.The performance of a mixed-ingredient paper sheet falls between the performance of two pure-component papers.For cost and performance reasons,adding a small amount of Wikstroemia(e.g.,<20%)to Edgeworthia is preferable.
文摘Wiksroemia indica belongs to the family of Thymelaeaceae.As a material of Traditional Chinese Medicine,it is mainly used to treat inflammation-related diseases.However,due to its complex composition,the scientific basis for its traditional application is still insufficient and the mechanism of action is still unclear.At present,most studies on its anti-inflammatory effect focus on a certain component and its different solvent fractions.There are few reports about the synergistic mechanism of the constituents from W.indica for the treatment of inflammatory diseases.Therefore,the present study aimed to uncover its potential mechanism from a holistic perspective using the network pharmacology approach.Firstly,compounds in W.indica and genes associated with inflammatory diseases were obtained.Then,the active compounds were screened out and their targets were predicted.After that,the key targets for W.indica to treat inflammatory diseases were screened out.Finally,the protein-protein interaction(PPI),Gene ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)enrichment analyses of key targets were performed to further study the mechanism of W.indica in the treatment of inflammatory diseases.The results showed that the active constituents of W.indica might play an anti-inflammatory role through the key targets CYP19A1 and CYP1B1,which clarified the primary mechanism for the treatment of inflammatory diseases and provided a scientific basis for further study of this herb.
文摘A new guaiane-type sesquiterpene, wiksphyllamin A （1） with C-10 and C-11 connected, along with fifteen known compounds were isolated from the stems of Wiks＇troemia scytophylla Diels. All these compounds were iso- lated for the first time from Wikstroemia scytophylla. The structures of 1--16 were identified using spectroscopic methods.
文摘Wikstroemia chamedaphne was investigated for its acarocidal activity against Tetranychus viennensis, a serious pest of many crops including apple trees in China. Its active constitutes were extracted,separated and purified. The results indicated that the extraction of petroleum ether from WCME （Wikstroemia chamaedaphne methanol extract） appeared a strong acarocidal activity. The adjusted mortalities of egg,larva and female mite were 74.48%,100.00% and 100.00% respectively, while the LC50 values were 2.106 2、0.304 1 and 0.771 6 mg·mL-1 respectively.
