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Native T1 mapping值显著延长心脏纤维瘤一例
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作者 文涛 张辉 +3 位作者 甘铁军 胡万均 李世兰 张静 《磁共振成像》 北大核心 2026年第1期120-122,共3页
本研究为回顾性研究,遵守《赫尔辛基宣言》,并经兰州大学第二医院伦理委员会审核批准,免除受试者知情同意,批准文号:2025A-547。患儿,女,2月8天,因“发现心脏肿瘤2月”于2024年11月就诊于我院,患儿于2个月前出生后外院检查提示左心室肿... 本研究为回顾性研究,遵守《赫尔辛基宣言》,并经兰州大学第二医院伦理委员会审核批准,免除受试者知情同意,批准文号:2025A-547。患儿,女,2月8天,因“发现心脏肿瘤2月”于2024年11月就诊于我院,患儿于2个月前出生后外院检查提示左心室肿瘤,未予特殊诊治,现为进一步明确诊治收住我院心脏外科。患儿足月(38+6周)、顺产、无心脏肿瘤家族史。查体:心前区无隆起,心界不大,心音有力、律齐,胸骨左缘第2~3肋间可闻及3/6及吹风样杂音,静息血氧饱和度100%。 展开更多
关键词 心脏肿瘤 心脏纤维瘤 多模态磁共振成像 心脏磁共振 Native T1 mapping
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T2 Mapping联合DWI序列评估直肠癌脉管侵犯价值研究
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作者 李茜玮 陈安良 +2 位作者 王楠 林良杰 刘爱连 《中国CT和MRI杂志》 2026年第1期149-152,共4页
目的探讨T2 mapping与DWI序列预测直肠癌脉管侵犯的价值。方法回顾性分析经本院行3.0T MRI扫描且经术后病理证实的直肠癌脉管侵犯13例,脉管非侵犯20例,2名观察者分别于瘤体显示最大层面参考增强动脉期图像及DWI图像于T2 mapping及ADC图... 目的探讨T2 mapping与DWI序列预测直肠癌脉管侵犯的价值。方法回顾性分析经本院行3.0T MRI扫描且经术后病理证实的直肠癌脉管侵犯13例,脉管非侵犯20例,2名观察者分别于瘤体显示最大层面参考增强动脉期图像及DWI图像于T2 mapping及ADC图像上测量病灶T2值及ADC值。采用组内相关系数(intraclass correlation cofficient,ICC)评估两名观察者测量参数值的一致性。采用独立样本t检验或Mann-Whitney U检验分析两组病例各参数的差异。采用Logistic回归计算有统计学差异的参数联合评估直肠癌LVI的预测值。采用ROC曲线评估有差异参数单独或联合的诊断效能,并利用De-Long检验比较各ROC曲线间的差异。采用Pearson相关性检验分析两参数值的相关性。结果2名观察者测量T2值及ADC值一致性好(ICC>0.75)。脉管侵犯组的T2值及ADC值低于非脉管侵犯组(77.15±6.95ms、0.69±0.15mm^(2)/s vs 87.04±7.75ms、0.90±0.21 mm^(2)/s,P<0.05)。ADC值与ADC-T2联合鉴别两组疾病的AUC值比较差异具有统计学意义(P=0.036)。结论T2 mapping和DWI序列可预测直肠癌脉管侵犯,两序列联合效能提升,因此T2值与ADC值联合可为临床诊疗直肠癌脉管侵犯提供参考信息。 展开更多
关键词 直肠癌 脉管侵犯 磁共振成像 T2 mapping成像 弥散加权成像
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A Comprehensive Literature Review of AI-Driven Application Mapping and Scheduling Techniques for Network-on-Chip Systems
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作者 Naveed Ahmad Muhammad Kaleem +5 位作者 Mourad Elloumi Muhammad Azhar Mushtaq Ahlem Fatnassi Mohd Fazil Anas Bilal Abdulbasit A.Darem 《Computer Modeling in Engineering & Sciences》 2026年第1期118-155,共38页
Network-on-Chip(NoC)systems are progressively deployed in connecting massively parallel megacore systems in the new computing architecture.As a result,application mapping has become an important aspect of performance ... Network-on-Chip(NoC)systems are progressively deployed in connecting massively parallel megacore systems in the new computing architecture.As a result,application mapping has become an important aspect of performance and scalability,as current trends require the distribution of computation across network nodes/points.In this paper,we survey a large number of mapping and scheduling techniques designed for NoC architectures.This time,we concentrated on 3D systems.We take a systematic literature review approach to analyze existing methods across static,dynamic,hybrid,and machine-learning-based approaches,alongside preliminary AI-based dynamic models in recent works.We classify them into several main aspects covering power-aware mapping,fault tolerance,load-balancing,and adaptive for dynamic workloads.Also,we assess the efficacy of each method against performance parameters,such as latency,throughput,response time,and error rate.Key challenges,including energy efficiency,real-time adaptability,and reinforcement learning integration,are highlighted as well.To the best of our knowledge,this is one of the recent reviews that identifies both traditional and AI-based algorithms for mapping over a modern NoC,and opens research challenges.Finally,we provide directions for future work toward improved adaptability and scalability via lightweight learned models and hierarchical mapping frameworks. 展开更多
关键词 Application mapping mapping techniques NETWORK-ON-CHIP system on chip optimisation
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High‑density genetic mapping enhances genomic selection accuracy for complex traits in Populus
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作者 Chenchen Guo Tongming Yin Suyun Wei 《Journal of Forestry Research》 2026年第2期290-304,共15页
Populus species,important economic species combining rapid growth with broad ecological adaptability,play a critical role in sustainable forestry and bioenergy production.In this study,we performed whole-genome resequ... Populus species,important economic species combining rapid growth with broad ecological adaptability,play a critical role in sustainable forestry and bioenergy production.In this study,we performed whole-genome resequencing of 707 individuals from a full-sib family to develop comprehensive single nucleotide polymorphism(SNP)markers and constructed a high-density genetic linkage map of 19 linkage groups.The total genetic length of the map reached 3623.65 cM with an average marker interval of 0.34 cM.By integrating multidimensional phenotypic data,89 quantitative trait loci(QTL)associated with growth,wood physical and chemical properties,disease resistance,and leaf morphology traits were identified,with logarithm of odds(LOD)scores ranging from 3.13 to 21.72 Notably,pleiotropic analysis revealed significant colocaliza and phenotypic variance explained between 1.7% and 11.6%.-tion hotspots on chromosomes LG1,LG5,LG6,LG8,and LG14,with epistatic interaction network analysis confirming genetic basis of coordinated regulation across multiple traits.Functional annotation of 207 candidate genes showed that R2R3-MYB and bHLH transcription factors and pyruvate kinase-encoding genes were significantly enriched,suggesting crucial roles in lignin biosynthesis and carbon metabolic pathways.Allelic effect analysis indicated that the frequency of favorable alleles associated with target traits ranged from 0.20 to 0.55.Incorporation of QTL-derived favorable alleles as random effects into Bayesian-based genomic selection models led to an increase in prediction accuracy ranging from 1% to 21%,with Bayesian ridge regression as the best predictive model.This study provides valuable genomic resources and genetic insights for deciphering complex trait architecture and advancing molecular breeding in poplar. 展开更多
关键词 Genomic selection Genetic map Quantitative trait loci GROWTH Disease resistance
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Comparative Study on the Diagnostic Efficacy of Conventional MRI Sequences and T2 Mapping Sequences in Cartilage Injury
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作者 Wang Peng Zhi Liu +1 位作者 Juan Long Chanying Wang 《Journal of Clinical and Nursing Research》 2026年第1期284-291,共8页
Objective:To retrospectively evaluate the diagnostic efficacy of traditional MRI and T2 Mapping quantitative imaging technology for knee joint cartilage injury,clarify the differences in diagnostic value of the two im... Objective:To retrospectively evaluate the diagnostic efficacy of traditional MRI and T2 Mapping quantitative imaging technology for knee joint cartilage injury,clarify the differences in diagnostic value of the two imaging methods in different injury grades and different cartilage subregions,and provide evidence-based basis for the accurate diagnosis of clinical cartilage injury.Methods:Clinical and imaging data of 286 patients with knee joint lesions admitted to the Affiliated Hospital of Xiangtan Medicine and Health Vocational College from January 2020 to June 2023 were collected retrospectively.All patients underwent both traditional MRI sequences and T2 Mapping sequences.The knee joint cartilage was divided into 14 subregions.Two senior radiologists independently diagnosed the images of the two imaging technologies using a blind method and recorded the cartilage injury grades.The sensitivity,specificity,accuracy,positive predictive value,negative predictive value,and area under the receiver operating characteristic curve(AUC)of the two technologies for diagnosing cartilage injury were calculated and compared,and the differences in their diagnostic efficacy in different injury grades and different subregions were analyzed.Results:A total of 4004 cartilage subregions from 286 patients were included in the analysis,including 1836 injured subregions and 2168 normal subregions.The overall sensitivity(89.7%),accuracy(91.2%),and AUC(0.946)of T2 Mapping quantitative imaging for diagnosing cartilage injury were significantly higher than those of traditional MRI(76.3%,82.5%,and 0.852 respectively),with statistically significant differences(p<0.001);there was no significant difference in specificity between the two(93.5%vs 90.8%,p=0.062).Subgroup analysis showed that T2 Mapping had the most significant diagnostic advantage in early cartilage injury(Grade 1),with sensitivity(78.5%)33.2%higher than that of traditional MRI(45.3%)(p<0.001).Conclusion:The diagnostic efficacy of T2 Mapping quantitative imaging for knee joint cartilage injury is significantly superior to that of traditional MRI,especially in the detection of early cartilage injury and accurate evaluation of weight-bearing area injury.Data verify its clinical applicability and reliability.It can be used as an important supplementary method to traditional MRI,and is recommended for the early diagnosis,grading evaluation,and clinical follow-up of cartilage injury. 展开更多
关键词 Traditional MRI T2 mapping Cartilage injury Diagnostic efficacy Retrospective analysis
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T2 mapping成像在踝关节骨性关节炎软骨退变评估中的应用价值
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作者 柴文武 《影像研究与医学应用》 2026年第4期106-108,共3页
目的:探讨T2 mapping成像在踝关节骨性关节炎(OA)软骨退变评估中的应用价值。方法:选取2025年1月—2025年9月徐州仁慈医院收治的60例踝关节OA患者(OA组)和50例健康体检志愿者(对照组)为研究对象,均行T2 mapping成像检查,比较两组负重区... 目的:探讨T2 mapping成像在踝关节骨性关节炎(OA)软骨退变评估中的应用价值。方法:选取2025年1月—2025年9月徐州仁慈医院收治的60例踝关节OA患者(OA组)和50例健康体检志愿者(对照组)为研究对象,均行T2 mapping成像检查,比较两组负重区、非负重区软骨T2值,并以关节镜结果为依据,参照软骨修复协会的分级标准将踝关节OA患者分为轻度损伤组(n=20)、中度损伤组(n=28)和重度损伤组(n=12),比较不同损伤分级踝关节OA患者软骨T2值差异。结果:OA组内、外踝骨的负重区与非负重区,以及距骨内侧前部、中部与后部的T2值均高于对照组(P<0.05);两组距骨外侧前部、中部、后部T2值比较,差异均无统计学意义(P>0.05)。重度损伤组距骨内侧前部、中部、后部T2值均高于中度损伤组、轻度损伤组,且中度损伤组距骨内侧前部、中部、后部T2值均高于轻度损伤组(P<0.05);不同损伤分级踝关节OA患者距骨外侧前部、中部、后部T2值比较,差异无统计学意义(P>0.05)。结论:T2 mapping成像能够量化评估踝关节软骨内部组织成分的变化,对早期踝关节OA的病情评估有一定的指导意义。 展开更多
关键词 踝关节 骨性关节炎 MRI T2 mapping 软骨损伤分级
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RNPC-net:Automatic recognition and mapping of weathering degree and groundwater condition of tunnel faces
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作者 Xiang Wu Fengyan Wang +4 位作者 Jianping Chen Mingchang Wang Lina Cheng Chengyao Zhang Junke Xu 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第2期1138-1159,共22页
Accurate and rapid recognition of weathering degree(WD)and groundwater condition(GC)is essential for evaluating rock mass quality and conducting stability analyses in underground engineering.Conventional WD and GC rec... Accurate and rapid recognition of weathering degree(WD)and groundwater condition(GC)is essential for evaluating rock mass quality and conducting stability analyses in underground engineering.Conventional WD and GC recognition methods often rely on subjective evaluation by field experts,supplemented by field sampling and laboratory testing.These methods are frequently complex and timeconsuming,making it challenging to meet the rapidly evolving demands of underground engineering.Therefore,this study proposes a rock non-geometric parameter classification network(RNPC-net)to rapidly achieve the recognition and mapping ofWD and GC of tunnel faces.The hybrid feature extraction module(HFEM)in RNPC-net can fully extract,fuse,and utilize multi-scale features of images,enhancing the network's classification performance.Moreover,the designed adaptive weighting auxiliary classifier(AC)helps the network learn features more efficiently.Experimental results show that RNPC-net achieved classification accuracies of 0.8756 and 0.8710 for WD and GC,respectively,representing an improvement of approximately 2%e10%compared to other methods.Both quantitative and qualitative experiments confirm the effectiveness and superiority of RNPC-net.Furthermore,for WD and GC mapping,RNPC-net outperformed other methods by achieving the highest mean intersection over union(mIOU)across most tunnel faces.The mapping results closely align with measurements provided by field experts.The application of WD and GC mapping results to the rock mass rating(RMR)system achieved a transition from conventional qualitative to quantitative evaluation.This advancement enables more accurate and reliable rock mass quality evaluations,particularly under critical conditions of RMR. 展开更多
关键词 Tunnel face Weathering degree Groundwater condition RNPC-net Hybrid feature extraction module Recognition and mapping
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Integration of Landsat and MODIS Imagery for Mapping 30-m Cotton Cultivation Areas in Xinjiang,China from 2000 to 2020
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作者 TAN Zhuting TAN Zhenyu +1 位作者 DUAN Hongtao ZHANG Kaili 《Chinese Geographical Science》 2026年第1期97-108,I0001,共13页
Cotton is an important global cash crops that serve as the primary source of natural fiber for textiles.A thorough understand-ing of the long-term variations in cotton cultivation is vital for optimizing cotton cultiv... Cotton is an important global cash crops that serve as the primary source of natural fiber for textiles.A thorough understand-ing of the long-term variations in cotton cultivation is vital for optimizing cotton cultivation management and promoting the sustainable development of the cotton industry.Xinjiang is the primary cotton-producing region in China.However,long-term data of cotton cultiv-ation areas with high spatial resolution are unavailable for Xinjiang,China.Therefore,this study aimed to identify and map an accurate 30-m cotton cultivation area dataset in Xinjiang from 2000 to 2020 by applying a Random Forest(RF)-based method that integrates Landsat and Moderate Resolution Imaging Spectroradiometer(MODIS)images,and validated the applicability and accuracy of dataset at a large spatial scale.Then,this study analyzed the spatiotemporal variations and influencing factors of cotton cultivation in the study period.The results showed that a high classification accuracy was achieved(overall accuracy>85%,F1>0.80),strongly agreeing with county-level agricultural statistical yearbook data(R2>0.72).Significant spatiotemporal variation in the cotton cultivation areas was found in Xinjiang,with a total increase of 1131.26 kha from 2000 to 2020.Notably,cotton cultivation area in southern Xinjiang expan-ded substantially,with that in Aksu increasing from 20.10%in 2000 to 28.17%in 2020,representing an expansion of 374.29 kha.In northern Xinjiang,the cotton areas in the Tacheng region also exhibited significant increased by almost ten percentage points in the same period.In contrast,cotton cultivation in eastern Xinjiang declined,decreasing from 2.22%in 2000 to merely 0.24%in 2020.Standard deviation ellipse analysis revealed a‘northeast-southwest’spatial distribution,with the centroid consistently located in Aksu and shifting 102.96 km over the 20-yr period.Pearson correlation analysis indicated that socioeconomic factors had a stronger influence on cotton cultivation than climatic factors,with effective irrigation area(r=0.963,P<0.05)and total agricultural machinery power(r=0.823)showing significant positive correlations,whereas climatic variables exhibiting weak associations(r<0.200).These results provide valuable scientific data for informed agricultural management,sustainable development,and policymaking. 展开更多
关键词 cotton cultivation mapping long-term series LANDSAT Moderate Resolution Imaging Spectroradiometer(MODIS) remote sensing Xinjiang China
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Large-scale urban building function mapping by integrating multi-source web-based geospatial data
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作者 Wei Chen Yuyu Zhou +1 位作者 Eleanor C.Stokes Xuesong Zhang 《Geo-Spatial Information Science》 CSCD 2024年第6期1785-1799,共15页
Morphological(e.g.shape,size,and height)and function(e.g.working,living,and shopping)information of buildings is highly needed for urban planning and management as well as other applications such as city-scale buildin... Morphological(e.g.shape,size,and height)and function(e.g.working,living,and shopping)information of buildings is highly needed for urban planning and management as well as other applications such as city-scale building energy use modeling.Due to the limited availability of socio-economic geospatial data,it is more challenging to map building functions than building morphological information,especially over large areas.In this study,we proposed an integrated framework to map building functions in 50 U.S.cities by integrating multi-source web-based geospatial data.First,a web crawler was developed to extract Points of Interest(POIs)from Tripadvisor.com,and a map crawler was developed to extract POIs and land use parcels from Google Maps.Second,an unsupervised machine learning algorithm named OneClassSVM was used to identify residential buildings based on landscape features derived from Microsoft building footprints.Third,the type ratio of POIs and the area ratio of land use parcels were used to identify six non-residential functions(i.e.hospital,hotel,school,shop,restaurant,and office).The accuracy assessment indicates that the proposed framework performed well,with an average overall accuracy of 94%and a kappa coefficient of 0.63.With the worldwide coverage of Google Maps and Tripadvisor.com,the proposed framework is transferable to other cities over the world.The data products generated from this study are of great use for quantitative city-scale urban studies,such as building energy use modeling at the single building level over large areas. 展开更多
关键词 Building functions geospatial data TripAdvisor Google Static maps
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3.0T磁共振T2 mapping序列联合血清新饱食分子蛋白1水平检测在老年膝关节早期骨关节炎诊断中的应用价值
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作者 唐利 巩玉荣 +2 位作者 曾立叶 高艳芳 邓成哲 《实用医学杂志》 北大核心 2025年第8期1238-1242,共5页
目的探讨3.0 T磁共振(MRI)T2 mapping序列联合血清新饱食分子蛋白1(nesfatin-1)水平对老年膝关节早期骨关节炎(OA)的诊断价值。方法选取2023年5月至2024年5月医院收治的膝关节OA的97例老年患者(OA组)和52例同期老年体检者(对照组),根据... 目的探讨3.0 T磁共振(MRI)T2 mapping序列联合血清新饱食分子蛋白1(nesfatin-1)水平对老年膝关节早期骨关节炎(OA)的诊断价值。方法选取2023年5月至2024年5月医院收治的膝关节OA的97例老年患者(OA组)和52例同期老年体检者(对照组),根据X线结果将膝关节OA组分为早期组和非早期组,均接受3.0T MRI T2 mapping序列扫描检测膝关节软骨区域T2值,检测血清nesfatin-1水平,比较上述指标差异并采用ROC曲线分析其对老年膝关节早期OA的诊断价值。结果97例老年膝关节OA患者中,早期组35例,非早期组62例,OA组患者膝关节5个软骨区域的T2值及nesfatin-1血清均高于对照组(P<0.05),早期组均低于非早期组(P<0.05);膝关节软骨区域T2值和血清nesfatin-1水平单独诊断早期OA的AUC在0.774~0.871范围,联合诊断的AUC为0.939。结论3.0 T磁共振T2 mapping序列联合血清nesfatin-1水平检测对老年膝关节早期OA具有较高的诊断价值。 展开更多
关键词 膝关节早期骨关节炎 老年 磁共振 T2 mapping序列 新饱食分子蛋白1
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MR T_(1)-mapping结合动脉自旋标记技术在评估儿童慢性肾脏病肾纤维化和灌注中的应用 被引量:1
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作者 赵佳佳 胡俊 +2 位作者 尹传高 顾东浩 朱晓冬 《临床放射学杂志》 北大核心 2025年第3期513-517,共5页
目的初步研究MR纵向弛豫时间定量成像(T 1-mapping)和动脉自旋标记技术(ASL)在诊断儿童慢性肾脏病(CKD)中的应用价值。方法纳入CKD患儿32例(包括肾脏未萎缩19例,萎缩13例),同期招募健康志愿者30名作对照组,行T 1-mapping和ASL序列扫描,... 目的初步研究MR纵向弛豫时间定量成像(T 1-mapping)和动脉自旋标记技术(ASL)在诊断儿童慢性肾脏病(CKD)中的应用价值。方法纳入CKD患儿32例(包括肾脏未萎缩19例,萎缩13例),同期招募健康志愿者30名作对照组,行T 1-mapping和ASL序列扫描,分别获得肾皮质T 1值和肾皮质血流量(RBF)。比较对照组和CKD组患儿肾皮质T 1值和RBF值的差异,并分析CKD组肾皮质T 1值和RBF值与估算肾小球滤过率(eGFR)、血肌酐(Scr)、血胱抑素C(Cys-C)的相关性。结果CKD组较对照组肾皮质T 1值明显升高、RBF值明显减低(P<0.05);CKD组中,肾脏未萎缩患儿肾皮质T 1值与eGRF、Scr、Cys-C呈高、中度相关(r=-0.832、0.777、0.698,P<0.05),肾脏萎缩患儿肾皮质T 1值与eGRF、Scr呈高度相关(r=0.726、-0.743,P<0.05);CKD组肾皮质RBF与eGRF、Cys-C、Scr呈中度相关(r=0.699、-0.619、-0.554,P<0.05)。结论MR T_(1)-mapping和ASL定量反映肾脏微观病理变化及血流灌注情况,具有预测肾脏慢性病理损伤的潜在价值,有望在肾脏发生不可逆损伤前早期、无创地提供肾脏功能信息。 展开更多
关键词 慢性肾脏病 儿童 T_(1)-mapping 动脉自旋标记 磁共振功能成像
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基于T_(2)mapping及超短回波时间技术定量探究早期膝骨关节炎的发病机制 被引量:4
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作者 牛飞格 孟祥虹 +1 位作者 孙曼 王植 《临床放射学杂志》 北大核心 2025年第2期350-356,共7页
目的基于浅表软骨的T_(2)mapping和骨软骨交界区(OCJ)的超短回波时间(UTE)T_(2)^(*)mapping探究膝骨关节炎(KOA)早期浅表软骨和骨软骨交界区的病变顺序。方法对纳入的30个健康膝和30个早期骨性关节炎膝进行常规和定量MRI扫描,主要扫描... 目的基于浅表软骨的T_(2)mapping和骨软骨交界区(OCJ)的超短回波时间(UTE)T_(2)^(*)mapping探究膝骨关节炎(KOA)早期浅表软骨和骨软骨交界区的病变顺序。方法对纳入的30个健康膝和30个早期骨性关节炎膝进行常规和定量MRI扫描,主要扫描序列包括三维水激发序列(3D WATS)、T_(2)mapping和UTE T_(2)^(*)mapping。将每个膝关节都分为股骨内侧髁、股骨外侧髁、胫骨内侧髁、胫骨外侧髁、髌骨和滑车区6个区域并测量每个区域的浅层软骨T_(2)值和OCJ T_(2)^(*)值。用独立样本t检验比较健康组和早期KOA组间的浅层软骨T_(2)值及OCJ T_(2)^(*)值。用Spearman相关性检验评估浅层软骨T_(2)值与OCJ T_(2)^(*)值间的相关性。结果早期KOA组的浅层软骨T_(2)值在股骨内侧髁(P<0.001)、胫骨内侧平台(P<0.001)、髌骨(P<0.001)和股骨滑车区(P=0.01)相对于健康组显著升高。早期KOA组OCJ T_(2)^(*)值在股骨内侧髁(P<0.001)、胫骨内侧平台(P<0.001)、胫骨外侧平台(P<0.001)、髌骨(P=0.001)和滑车区(P<0.001)均显著升高。浅层软骨T_(2)值和骨软骨交界区T_(2)^(*)值间存在正相关关系(r=0.37,P<0.001)。结论浅表软骨的T_(2)mapping和骨软骨交界区的UTE T_(2)^(*)mapping成像都可定量且无创识别早期KOA。在KOA早期,浅表软骨和OCJ都出现了生化改变。 展开更多
关键词 骨性关节炎 关节软骨骨软骨交界区 T_(2)mapping T_(2)^(*)mapping
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基于磁共振T1 mapping影像组学胰腺导管腺癌间质比定量评估模型的开发与临床验证
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作者 张心悦 陈成伟 +4 位作者 袁小涵 沈奕暄 陈士跃 边云 陆建平 《海军军医大学学报》 北大核心 2025年第12期1597-1603,共7页
目的开发基于MRI T1 mapping影像组学的胰腺导管腺癌(PDAC)间质含量无创评估模型。方法前瞻性纳入2023年6月至2024年12月海军军医大学第一附属医院157例经术后病理确诊的PDAC患者。从T1 mapping图像提取12442个特征并筛选出10个关键特征... 目的开发基于MRI T1 mapping影像组学的胰腺导管腺癌(PDAC)间质含量无创评估模型。方法前瞻性纳入2023年6月至2024年12月海军军医大学第一附属医院157例经术后病理确诊的PDAC患者。从T1 mapping图像提取12442个特征并筛选出10个关键特征,采用最小绝对收缩和选择算子回归对10个关键特征进行线性组合及加权计算,得到影像组学评分(Rad_Score)。采用Spearman秩相关检验Rad_Score与间质含量的相关性。以病理诊断的间质含量为金标准,通过ROC曲线评估Rad_Score的诊断效能。采用多重线性回归建立间质含量预测方程(纳入Rad_Score与肿瘤最大径),采用Bland-Altman法检验预测值与实际值的一致性。结果在PADC患者中Rad_Score与间质含量相关(rs=0.52,P<0.001),Rad_Score预测间质含量>0.5的AUC值为0.936(95%CI 0.885~0.987)、灵敏度为91.7%、特异度为88.0%。基于Rad_Score和肿瘤最大径构建的线性回归预测模型为:间质含量=0.592+0.037×Rad_Score-0.025×肿瘤最大径(cm);Bland-Altman法分析显示其预测的间质含量与实际值一致性较好(平均偏差为0.00,95%一致性界限为-0.33~0.33)。结论基于MRI T1 mapping影像组学建立的PDAC间质评估模型对高、低间质含量有较好的区分价值。 展开更多
关键词 磁共振成像 T1 mapping 胰腺导管腺癌 间质比 影像组学 深度学习 多模态 无创评估
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重新联结生活世界:詹姆斯·科纳Mapping理论的批判性实践 被引量:1
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作者 陈永明 周启明 《建筑师》 2025年第2期100-110,共11页
詹姆斯·科纳的Mapping理论一直备受学界的高度关注。本文围绕科纳在Mapping理论探索中对“具身性感知”与“理性测量”的反思,厘清Mapping中“批判性实践”的理论内涵,并指出其在智识性的思辨和想象性的建构两个方面所展开的理论... 詹姆斯·科纳的Mapping理论一直备受学界的高度关注。本文围绕科纳在Mapping理论探索中对“具身性感知”与“理性测量”的反思,厘清Mapping中“批判性实践”的理论内涵,并指出其在智识性的思辨和想象性的建构两个方面所展开的理论逻辑。随后以科纳的霍皮人天气日历、十的次方和西雅图海滨公园设计等三个作品为例,阐述了Mapping操作的方法和特征,以及其对重新联结生活世界的价值和启示。 展开更多
关键词 mapping 批判性实践 复合性操作 具身性 日常生活 诗意
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酰胺质子转移加权成像及T2 mapping成像对子宫内膜样腺癌微卫星不稳定状态的预测价值
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作者 程连华 常玲玉 +3 位作者 于德新 王青 贾进正 王芳 《中国医学科学院学报》 北大核心 2025年第6期947-953,共7页
目的探讨酰胺质子转移加权成像(APTw)及T2 mapping在评估子宫内膜样腺癌微卫星不稳定性(MSI)的价值。方法前瞻性纳入临床疑似为子宫内膜癌的患者,所有患者术前均行APTw及T2 mapping成像。两名放射科医师分别行感兴趣区的勾画及定量参数... 目的探讨酰胺质子转移加权成像(APTw)及T2 mapping在评估子宫内膜样腺癌微卫星不稳定性(MSI)的价值。方法前瞻性纳入临床疑似为子宫内膜癌的患者,所有患者术前均行APTw及T2 mapping成像。两名放射科医师分别行感兴趣区的勾画及定量参数的测量。经组内相关系数检验两位医师所测MRI参数值的一致性;采用独立样本t检验或者Mann-Whitney U检验比较MSI组与微卫星稳定(MSS)组之间定量参数的差异;经受试者工作特征曲线评估各序列的诊断效能;采用DeLong检验比较单一参数及联合序列之间曲线下面积(AUC)的差异。结果共纳入MSI组患者21例,MSS组患者37例。两名医师所测结果一致性好。MSI组APTw值显著高于MSS组[(2.72±0.52)%比(2.08±0.39)%,P<0.001];T2值显著低于MSS组[92.25(90.82,99.91)ms比101.80(96.15,112.13)ms,P<0.001]。受试者工作特征曲线显示APTw、T2 mapping序列的AUC值分别为0.821(95%CI=0.698~0.909)、0.793(95%CI=0.666~0.888),两种序列的诊断效能差异无统计学意义(P=0.692);当两序列联合时,AUC值提高至0.897(95%CI=0.789~0.961),较单一APTw及T2 mapping序列的诊断效能均显著提高(P=0.042,P=0.025)。结论APTw及T2 mapping成像在评估子宫内膜样腺癌患者MSI状态方面具有一定的临床价值,两者联合显示出更高的诊断效能,为患者术前治疗方式的选择提供有效依据。 展开更多
关键词 子宫内膜样腺癌 酰胺质子转移加权成像 T2 mapping 微卫星不稳定性
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磁共振T2-mapping成像技术在膝关节骨性关节炎诊断中应用的研究进展
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作者 陈思 《黑龙江医学》 2025年第16期2042-2044,2048,共4页
T2-mapping成像技术通过分析软骨的T2弛豫时间,定量评估软骨组织学结构,揭示软骨中水含量和胶原纤维排列的变化,适用于早期检测软骨损伤和监测疾病进展,对评估软骨健康状况至关重要。T2-mapping成像技术不仅对膝关节骨性关节炎(KOA)的... T2-mapping成像技术通过分析软骨的T2弛豫时间,定量评估软骨组织学结构,揭示软骨中水含量和胶原纤维排列的变化,适用于早期检测软骨损伤和监测疾病进展,对评估软骨健康状况至关重要。T2-mapping成像技术不仅对膝关节骨性关节炎(KOA)的早期诊断和进展监测具有重要价值,还能在软骨修复过程中监测和评估软骨的生化变化。随着成像技术和数据处理能力的进一步发展,T2-mapping成像有望提高诊断精度、优化治疗方案,为KOA的管理和治疗带来革新。文章综述了磁共振成像技术(MRI)中的T2-mapping成像技术在KOA诊断和评估中的应用。 展开更多
关键词 磁共振T2-mapping成像 膝关节 骨性关节炎
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基于T2^(*)mapping的业余马拉松运动员足踝部关节软骨损伤及其影响因素分析 被引量:2
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作者 高雅丽 兰晓川 +2 位作者 王舒 宋凌恒 陈伟 《磁共振成像》 北大核心 2025年第2期94-99,共6页
目的基于T2^(*)mapping定量分析业余马拉松运动员足踝部关节软骨的T2^(*)值,并分析其与性别、年龄、身体质量指数(body mass index,BMI)、跑龄、跑量之间的相关性。材料与方法于2023年7月份至2023年9月份招募重庆市长跑运动爱好者48名,... 目的基于T2^(*)mapping定量分析业余马拉松运动员足踝部关节软骨的T2^(*)值,并分析其与性别、年龄、身体质量指数(body mass index,BMI)、跑龄、跑量之间的相关性。材料与方法于2023年7月份至2023年9月份招募重庆市长跑运动爱好者48名,其中跑量<300 km/月的36例(中低跑量组),跑量≥300 km/月的12例(高跑量组)。所有受试者均进行单侧无症状踝关节的MRI扫描,扫描序列包括T2^(*)mapping多回波自旋回波(spin echo,SE)序列矢状位、质子密度加权成像脂肪抑制(proton density-weighted imaging fat-saturated,PDWI-FS)序列矢状位、冠状位、横轴位以及T1加权脂肪抑制成像(T1-weighted imaging fat-saturated,T1WI-FS)序列横轴位。沿关节软骨轮廓边缘勾画距骨穹窿、跟骰关节跟骨面、骰骨面及后距下关节跟骨面、距骨面软骨作为感兴趣区(region of interest,ROI),获得相应的T2^(*)值。采用线性回归分析软骨T2^(*)值与年龄、BMI、跑龄的相关性,采用独立样本t检验分析不同跑量及不同性别间的软骨T2^(*)值差异。结果(1)距骨穹窿、跟骰关节跟骨面及骰骨面、后距下关节跟骨面及距骨面软骨T2^(*)值在性别上的差异均具有统计学意义(P=0.001、P<0.001、P=0.002、P=0.008、P=0.004);(2)高跑量组的距骨穹窿、后距下关节跟骨面软骨T2^(*)值高于中低跑量组(P=0.014、0.023),不同跑量的跟骰关节跟骨面及骰骨面、后距下关节距骨面软骨T2^(*)值的差异均无统计学意义(P=0.987、0.072、0.724);(3)距骨穹窿、跟骰关节跟骨面及骰骨面、后距下关节跟骨面、距骨面软骨T2^(*)值均与BMI呈正相关(r=0.376、0.384、0.300、0.422、0.455,P=0.005、0.004、0.019、0.001、0.001)。结论在业余马拉松运动员这一跑步群体中,与中低跑量相比,高跑量更有可能导致距骨穹窿、后距下关节跟骨面软骨损伤;而与较低的BMI相比,高BMI增加了距骨穹窿、跟骰关节跟骨面、骰骨面及后距下关节跟骨面、距骨面软骨损伤的风险。 展开更多
关键词 业余马拉松 跑步 软骨 磁共振成像 T2^(*)mapping
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磁共振T2mapping技术在布氏杆菌性脊柱炎诊断中的应用 被引量:2
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作者 张小娟 胡娜 +2 位作者 李宇璞 赵鹏飞 乔鹏飞 《中国CT和MRI杂志》 2025年第4期172-175,共4页
目的研究旨在探讨磁共振T2mapping技术在布氏杆菌性脊柱炎定量诊断中的应用价值。方法对病例组42例布氏杆菌脊柱炎患者及对照组43例健康志愿者行腰椎常规MRI+T2mapping检查,测量病例组患者病变椎体、病变邻近正常椎体及对照组健康椎体的... 目的研究旨在探讨磁共振T2mapping技术在布氏杆菌性脊柱炎定量诊断中的应用价值。方法对病例组42例布氏杆菌脊柱炎患者及对照组43例健康志愿者行腰椎常规MRI+T2mapping检查,测量病例组患者病变椎体、病变邻近正常椎体及对照组健康椎体的T2mapping值,并进行统计分析。结果病例组42例患者中,男性中老年多见;病变以L4-L5椎体受累及侵犯相邻2个椎体多见;病变椎体附近软组织水肿发生率较高,约78.57%;椎旁脓肿发生率较低约27.27%;邻近硬膜囊受到压迫、椎管有效矢状径变窄约16.67%。病例组病变椎体的T2mapping值较病变邻近正常椎体及对照组健康椎体T2mapping值明显增高且差异有统计学意义(P<0.05)。病例组病变邻近正常椎体与对照组健康椎体T2mapping值相比较,差异无统计学意义(P>0.05)。结论T2mapping技术可以量化分析布氏杆菌性脊柱炎患者椎体的情况,对布氏杆菌性脊柱炎的诊断有重要参考价值。 展开更多
关键词 T2mapping 定量 布氏杆菌病 腰椎 脊柱炎
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T2 mapping与3D-WATSc序列定量测量膝关节软骨体积的一致性 被引量:2
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作者 吴明杰 许亚飞 +2 位作者 傅孙亚 张玉琴 徐凌斌 《中国医学影像学杂志》 北大核心 2025年第3期320-325,共6页
目的探索T2 mapping与三维选择性水激发(3D-WATSc)序列测量膝关节软骨体积的一致性。资料与方法2022年5—12月宁波大学附属李惠利医院招募30名健康志愿者,行左膝关节3D-WATSc、T2mapping序列扫描。随机抽取20名受试者的T2 mapping序列,... 目的探索T2 mapping与三维选择性水激发(3D-WATSc)序列测量膝关节软骨体积的一致性。资料与方法2022年5—12月宁波大学附属李惠利医院招募30名健康志愿者,行左膝关节3D-WATSc、T2mapping序列扫描。随机抽取20名受试者的T2 mapping序列,分析8组不同TE(13、26、39、52、65、78、91、104 ms)的原始图像,由2名观察者对原始图像质量进行评分,使用Kappa检验观察评分一致性,Welch方差分析和Games-Howell text事后检验得出最佳图像质量的TE。基于T2 mapping和3D-WATSc序列对30名受试者股骨髁、胫骨平台和髌骨后缘软骨体积进行半自动分割测量,使用组内相关系数(ICC)、BlandAltman检验T2 mapping序列下2名观察者间及两种序列测得软骨体积的一致性。结果2名观察者评分除TE 104 ms一致性较差(Kappa=0.318)、TE 78 ms差异无统计学意义(P=0.052)外,其余一致性均为中等(Kappa>0.40,P<0.05),进一步分析TE 26 ms软骨显示质量评分最佳(均值2.90)。将TE 26 ms与其余7组评分进行Games-Howell text两两比较,除与TE 13 ms(均值2.55)、TE 39 ms(均值2.62)两组评分差异无统计学意义(P>0.05)外,TE 26 ms与其余TE组评分差异均有统计学意义(P均<0.05)。在T2 mapping(TR 2000 ms、TE 26 ms)序列上,2名观察者分割得到各部分软骨体积的ICC均>0.6,P<0.05,以股骨髁软骨体积的一致性最好(ICC=0.877,P<0.01)。两种序列测得的各部分软骨体积一致性均较好(ICC均>0.75,P均<0.01),以胫骨平台软骨体积的一致性最好(ICC=0.857,P<0.01)。结论T2 mapping原始图像(TR 2000 ms、TE 26 ms)可清晰显示膝关节软骨形态,T2 mapping与3D-WATSc序列定量膝关节软骨体积的一致性较好,T2 mapping单一序列可为膝关节软骨形态及功能的一站式定量分析提供可信的扫描方案。 展开更多
关键词 磁共振成像 T2 mapping 三维选择性水激发序列 膝关节 软骨 体积
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