Motion simulator usually appears the phenomenon of false cues and the workspace is limited in the process of washout. The proposed washout algorithm combines fuzzy logic control with the vestibular system to design th...Motion simulator usually appears the phenomenon of false cues and the workspace is limited in the process of washout. The proposed washout algorithm combines fuzzy logic control with the vestibular system to design the tilt coordination fuzzy adaptive filter, in order to minimize the vestibular sensory error below the human perception threshold. Owing to tilt coordination angular velocity limiter, the loss of low-pass acceleration must be compensated by the acceleration transform model. The translational channel decreases the possibility of the workspace beyond limitation and expands the scope of motion platform simulating input acceleration by using third-order filter. The simulation results show that the proposed algorithm can effectively overcome the phase retardation of classical washout algorithm, and then prevent the produce of false cues, decrease the displacement of motion platform simultaneously; in addition, white Gaussian noise simulates large variations in acceleration. The proposed washout algorithm can have maximal extreme value of acceleration and accurate simulating performance in general. It also proves that the proposed washout algorithm has a strong adaptability and reliability, which can effectively improve the dynamic fidelity for motion simulator.展开更多
The washout resistance of injectable calcium phosphate cement（CPC） is highly requisite for more widely clinical applications. In this work, locust bean gum（LBG） was used as the anti-washout agent to improve the wa...The washout resistance of injectable calcium phosphate cement（CPC） is highly requisite for more widely clinical applications. In this work, locust bean gum（LBG） was used as the anti-washout agent to improve the washout resistance of CPC. The results indicated that the washout resistance was greatly improved,and meanwhile the injectability, setting time and compressive strength slightly decreased when the content of LBG was no more than 1.0%. Additionally, the CPC with 1.0% LBG exhibited good cell compatibility of the mouse bone mesenchymal stem cells（mBMSCs）. Therefore, the 1.0% LBG content was proposed to serve as a useful additive in CPC as a result of its ability to promote washout resistance, which may play an important role in clinical applications.展开更多
Animals’ regional femur blood (F) alteration was studied under an inadequate decompression by using the inhaled isotope 133Xe washout method. Results showed that the average F on left and right side of minipigs’ fem...Animals’ regional femur blood (F) alteration was studied under an inadequate decompression by using the inhaled isotope 133Xe washout method. Results showed that the average F on left and right side of minipigs’ femur decreased from 15.4±1.8 and 16 .9±2.0 ml/ (100 g.min) (before exposure) to 10±1.8 and 11.1±1.6 ml/(100mg.min) (after expposure for 1.5 h under the pressure of 0.5 MPa and then decompression to normal with the rate of 0.03~0.04MPa/min), respectively; the blood flow of hematopoietic marrow tissues (f1)on both sides also decreased from 19.3±2.0 and 22.1±1.9 ml/(100mg.min) to 13.9±1.4 and 13.8±1.0 ml/(100 mg.min). The exact same alteration also happened in the experiment on New Zealand rabbits. It indicates that inadequate decompression in hyperbaric exposure can give rise to decrease animals’ bone blood flow and insufficient bone blood supply serves as one of the reasons for causing decompressive osteonecrosis.展开更多
Importance:The forced oscillation (FOT) and multiple breath washout (MBW) techniques are passive tests of lung function,and are reliable for preschool-age children.There has not been comparison testing to determine wh...Importance:The forced oscillation (FOT) and multiple breath washout (MBW) techniques are passive tests of lung function,and are reliable for preschool-age children.There has not been comparison testing to determine which test could more accurately differentiate between healthy controls and poorly controlled asthmatics,or differentiate a response to bronchodilator administration.Objective:To determine whether the MBW and/or FOT could differentiate between healthy controls and poorly controlled asthmatics,and whether the two tests could detect a response to bronchodilator administration.Methods:Twenty-eight healthy controls and 23 poorly controlled asthmatics 3-6 years of age participated.All subjects were administered the MBW followed by the FOT.A bronchodilator was then administered and testing was repeated.Wilcoxon Rank Sum tests were used to compare the difference between healthy controls and poorly controlled asthmatics.Wilcoxon Signed Rank tests were used to compare the pre-and post-bronchodilator values.Results:Neither MBW nor FOT differentiated healthy controls from poorly controlled asthmatics (pre-bronchodilator data);both groups had similar baseline gas mixing and airway mechanics.There was no improvement in any MBW outcomes post-bronchodilator administration.FOT detected a significant and similar degree of improvement in the airway mechanics in both groups.Interpretation:Neither MBW nor FOT differentiated between poorly controlled asthmatics (when well) and healthy controls.MBW did not detect a significant bronchodilator response in either subject group,whereas FOT detected a similar degree of bronchodilator responsiveness in both groups.This discrepancy may reflect differential changes in airway mechanics and gas mixing properties in response to bronchodilators.展开更多
基金Funded by the National Natural Science Foundation of China(U1233107)Civil Aviation Science and Technology Innovation Project of China(MHRD20140210)
文摘Motion simulator usually appears the phenomenon of false cues and the workspace is limited in the process of washout. The proposed washout algorithm combines fuzzy logic control with the vestibular system to design the tilt coordination fuzzy adaptive filter, in order to minimize the vestibular sensory error below the human perception threshold. Owing to tilt coordination angular velocity limiter, the loss of low-pass acceleration must be compensated by the acceleration transform model. The translational channel decreases the possibility of the workspace beyond limitation and expands the scope of motion platform simulating input acceleration by using third-order filter. The simulation results show that the proposed algorithm can effectively overcome the phase retardation of classical washout algorithm, and then prevent the produce of false cues, decrease the displacement of motion platform simultaneously; in addition, white Gaussian noise simulates large variations in acceleration. The proposed washout algorithm can have maximal extreme value of acceleration and accurate simulating performance in general. It also proves that the proposed washout algorithm has a strong adaptability and reliability, which can effectively improve the dynamic fidelity for motion simulator.
基金supported by the National Natural Science Foundation of China (Grant No.51172074)the National High Technology Research and Development Program of China (Grant No.2015AA033601)+1 种基金the Science and Technology Program of Guangzhou City of China (Grant No.201508020017)the Research Foundation for the Author of the Excellent Doctoral Dissertation of Guangdong Province (Grant No.sybzzxm 201024)
文摘The washout resistance of injectable calcium phosphate cement（CPC） is highly requisite for more widely clinical applications. In this work, locust bean gum（LBG） was used as the anti-washout agent to improve the washout resistance of CPC. The results indicated that the washout resistance was greatly improved,and meanwhile the injectability, setting time and compressive strength slightly decreased when the content of LBG was no more than 1.0%. Additionally, the CPC with 1.0% LBG exhibited good cell compatibility of the mouse bone mesenchymal stem cells（mBMSCs）. Therefore, the 1.0% LBG content was proposed to serve as a useful additive in CPC as a result of its ability to promote washout resistance, which may play an important role in clinical applications.
文摘Animals’ regional femur blood (F) alteration was studied under an inadequate decompression by using the inhaled isotope 133Xe washout method. Results showed that the average F on left and right side of minipigs’ femur decreased from 15.4±1.8 and 16 .9±2.0 ml/ (100 g.min) (before exposure) to 10±1.8 and 11.1±1.6 ml/(100mg.min) (after expposure for 1.5 h under the pressure of 0.5 MPa and then decompression to normal with the rate of 0.03~0.04MPa/min), respectively; the blood flow of hematopoietic marrow tissues (f1)on both sides also decreased from 19.3±2.0 and 22.1±1.9 ml/(100mg.min) to 13.9±1.4 and 13.8±1.0 ml/(100 mg.min). The exact same alteration also happened in the experiment on New Zealand rabbits. It indicates that inadequate decompression in hyperbaric exposure can give rise to decrease animals’ bone blood flow and insufficient bone blood supply serves as one of the reasons for causing decompressive osteonecrosis.
文摘Importance:The forced oscillation (FOT) and multiple breath washout (MBW) techniques are passive tests of lung function,and are reliable for preschool-age children.There has not been comparison testing to determine which test could more accurately differentiate between healthy controls and poorly controlled asthmatics,or differentiate a response to bronchodilator administration.Objective:To determine whether the MBW and/or FOT could differentiate between healthy controls and poorly controlled asthmatics,and whether the two tests could detect a response to bronchodilator administration.Methods:Twenty-eight healthy controls and 23 poorly controlled asthmatics 3-6 years of age participated.All subjects were administered the MBW followed by the FOT.A bronchodilator was then administered and testing was repeated.Wilcoxon Rank Sum tests were used to compare the difference between healthy controls and poorly controlled asthmatics.Wilcoxon Signed Rank tests were used to compare the pre-and post-bronchodilator values.Results:Neither MBW nor FOT differentiated healthy controls from poorly controlled asthmatics (pre-bronchodilator data);both groups had similar baseline gas mixing and airway mechanics.There was no improvement in any MBW outcomes post-bronchodilator administration.FOT detected a significant and similar degree of improvement in the airway mechanics in both groups.Interpretation:Neither MBW nor FOT differentiated between poorly controlled asthmatics (when well) and healthy controls.MBW did not detect a significant bronchodilator response in either subject group,whereas FOT detected a similar degree of bronchodilator responsiveness in both groups.This discrepancy may reflect differential changes in airway mechanics and gas mixing properties in response to bronchodilators.
