Based on the questionnaire survey for 431 new generation minority migrant workers in Kunming City,we carried out empirical research on education demands of these migrant workers and its influence factors.Survey result...Based on the questionnaire survey for 431 new generation minority migrant workers in Kunming City,we carried out empirical research on education demands of these migrant workers and its influence factors.Survey results show that their education demands have significant features in learning purposes,contents,expenses,willingness,and manners,which are subject to subjective mentality,economic income,social relation network,as well as shortage in social supply of education and training.Therefore,apart from solving training problem of new generation minority migrant workers,government should also highly value their demands of training and arouse their enthusiasm for participation in training in accordance with cultural and psychological characteristics and living environment of these migrant workers.展开更多
Background:This is an exploratory study using multimodal magnetic resonance imaging(MRI)to interrogate the brain of rats with type 2 diabetes(T2DM)as compared to controls.It was hypothesized there would be changes in ...Background:This is an exploratory study using multimodal magnetic resonance imaging(MRI)to interrogate the brain of rats with type 2 diabetes(T2DM)as compared to controls.It was hypothesized there would be changes in brain structure and function that reflected the human disorder,thus providing a model system by which to follow disease progression with noninvasive MRI.Methods:The transgenic BBZDR/Wor rat,an animal model of T2MD,and agematched controls were studied for changes in brain structure using voxel-based morphometry,alteration in white and gray matter microarchitecture using diffusion weighted imaging with indices of anisotropy,and functional coupling using restingstate BOLD functional connectivity.Images from each modality were registered to,and analyzed,using a 3D MRI rat atlas providing site-specific data on over 168 different brain areas.Results:There was an overall reduction in brain volume focused primarily on the somatosensory cortex,cerebellum,and white matter tracts.The putative changes in white and gray matter microarchitecture were pervasive affecting much of the brain and not localized to any region.There was a general increase in connectivity in T2DM rats as compared to controls.The cerebellum presented with strong functional coupling to pons and brainstem in T2DM rats but negative connectivity to hippocampus.Conclusion:The neuroradiological measures collected in BBBKZ/Wor rats using multimodal imaging methods did not reflect those reported for T2DB patients in the clinic.The data would suggest the BBBKZ/Wor rat is not an appropriate imaging model for T2DM.展开更多
基金Supporte by the Project of Yunnan Provincial Department of Education(09Y0358)the Project of Kunming University(2010SH01)
文摘Based on the questionnaire survey for 431 new generation minority migrant workers in Kunming City,we carried out empirical research on education demands of these migrant workers and its influence factors.Survey results show that their education demands have significant features in learning purposes,contents,expenses,willingness,and manners,which are subject to subjective mentality,economic income,social relation network,as well as shortage in social supply of education and training.Therefore,apart from solving training problem of new generation minority migrant workers,government should also highly value their demands of training and arouse their enthusiasm for participation in training in accordance with cultural and psychological characteristics and living environment of these migrant workers.
基金The financial support was provided in part by an HHMI-funded Inclusive Excellence Award to Northeastern University,PIOndrechen。
文摘Background:This is an exploratory study using multimodal magnetic resonance imaging(MRI)to interrogate the brain of rats with type 2 diabetes(T2DM)as compared to controls.It was hypothesized there would be changes in brain structure and function that reflected the human disorder,thus providing a model system by which to follow disease progression with noninvasive MRI.Methods:The transgenic BBZDR/Wor rat,an animal model of T2MD,and agematched controls were studied for changes in brain structure using voxel-based morphometry,alteration in white and gray matter microarchitecture using diffusion weighted imaging with indices of anisotropy,and functional coupling using restingstate BOLD functional connectivity.Images from each modality were registered to,and analyzed,using a 3D MRI rat atlas providing site-specific data on over 168 different brain areas.Results:There was an overall reduction in brain volume focused primarily on the somatosensory cortex,cerebellum,and white matter tracts.The putative changes in white and gray matter microarchitecture were pervasive affecting much of the brain and not localized to any region.There was a general increase in connectivity in T2DM rats as compared to controls.The cerebellum presented with strong functional coupling to pons and brainstem in T2DM rats but negative connectivity to hippocampus.Conclusion:The neuroradiological measures collected in BBBKZ/Wor rats using multimodal imaging methods did not reflect those reported for T2DB patients in the clinic.The data would suggest the BBBKZ/Wor rat is not an appropriate imaging model for T2DM.
