Ulsan port is the hugest industry-oriented port in South Korea. It has the third highest traffic volume of cargo, and also it has the most liquid bulk in Korea. However, on account of thoughtless development, there ar...Ulsan port is the hugest industry-oriented port in South Korea. It has the third highest traffic volume of cargo, and also it has the most liquid bulk in Korea. However, on account of thoughtless development, there are other cases like Ulsan port that liquid cargo and general cargo are simultaneously handled. The demurrage ratio takes up to 12.5% of probability on average. In 2010, it has less room at berths for liquid bulk than general cargo and it totally has 107% of processing ratio (throughput). This indicates that Ulsan port concentrates on liquid cargo more than general cargo depending on the characteristics of the port. This research suggests the effects as alternatives for efficiency and effectivity at both ports, Ulsan port and Pohang port in the case that the general cargo handled in Ulsan port is relocated to Pohang port in terms of the characteristics of products which Pohang port and its hinterland the most focused on. Namely, we estimate volume of relocated volume suitable for relocation in assumption that volume handled in Ulsan port is relocated to Pohang port scenario by scenario, analyze the effects of relocated volume, and suggest alternatives for vitalizing Ulsan port.展开更多
Pulpotomy,which belongs to vital pulp therapy,has become a strategy for managing pulpitis in recent decades.This minimally invasive treatment reflects the recognition of preserving healthy dental pulp and optimizing l...Pulpotomy,which belongs to vital pulp therapy,has become a strategy for managing pulpitis in recent decades.This minimally invasive treatment reflects the recognition of preserving healthy dental pulp and optimizing long-term patient-centered outcomes.Pulpotomy is categorized into partial pulpotomy(PP),the removal of a partial segment of the coronal pulp tissue,and full pulpotomy(FP),the removal of whole coronal pulp,which is followed by applying the biomaterials onto the remaining pulp tissue and ultimately restoring the tooth.Procedural decisions for the amount of pulp tissue removal or retention depend on the diagnostic of pulp vitality,the overall treatment plan,the patient’s general health status,and pulp inflammation reassessment during operation.This statement represents the consensus of an expert committee convened by the Society of Cariology and Endodontics,Chinese Stomatological Association.It addresses the current evidence to support the application of pulpotomy as a potential alternative to root canal treatment(RCT)on mature permanent teeth with pulpitis from a biological basis,the development of capping biomaterial,and the diagnostic considerations to evidence-based medicine.This expert statement intends to provide a clinical protocol of pulpotomy,which facilitates practitioners in choosing the optimal procedure and increasing their confidence in this rapidly evolving field.展开更多
Open government-enterprise communication lies behind Qingdao’s success in attracting German investment.Aconducive business environment is crucial for stimulating economic vitality and driving high-quality development.
Objective: To assess the impact of preoperative psychological interventions on the care of patients undergoing elective surgery. Methods: Ninety-two patients scheduled for elective surgery in the surgical department b...Objective: To assess the impact of preoperative psychological interventions on the care of patients undergoing elective surgery. Methods: Ninety-two patients scheduled for elective surgery in the surgical department between August 2021 and August 2023 were selected and divided into groups using a random number table. The observation group received preoperative psychological interventions, while the reference group received standard preoperative care. Anxiety and depression scores, fear grading, vital signs, and self-efficacy levels were compared. Results: After the intervention, the anxiety and depression scores in the observation group were lower than those in the reference group, and the proportion of fear graded as Level I was higher. During the waiting period and 15 minutes before entering the operating room, vital sign levels in the observation group were lower than those in the reference group. Additionally, the self-efficacy scores of the observation group were significantly higher than those of the reference group (P < 0.05). Conclusion: Preoperative psychological interventions can alleviate negative emotions, stabilize preoperative vital signs, and significantly improve self-efficacy in patients undergoing elective surgery, demonstrating high feasibility for implementation.展开更多
The blood-brain barrier(BBB),an intricate interface of the neurovascular unit,plays a vital role in maintaining the function of the central nervous system(CNS).The BBB interacts with various components,such as glial c...The blood-brain barrier(BBB),an intricate interface of the neurovascular unit,plays a vital role in maintaining the function of the central nervous system(CNS).The BBB interacts with various components,such as glial cells,circulating cells,exosomes,and hormones,to regulate communication between the CNS and the periphery[1].展开更多
Urban environments offer a wealth of opportunities for residents to respite from their hectic life.Outdoor running or jogging becomes increasingly popular of an option.Impacts of urban environments on outdoor running,...Urban environments offer a wealth of opportunities for residents to respite from their hectic life.Outdoor running or jogging becomes increasingly popular of an option.Impacts of urban environments on outdoor running,despite some initial studies,remain underexplored.This study aims to establish an analytical framework that can holistically assess the urban environment on the healthy vitality of running.The proposed framework is applied to two modern Chinese cities,i.e.,Guangzhou and Shenzhen.We construct three interpretable random forest models to explore the non-linear relationship between environmental variables and running intensity(RI)through analyzing the runners'trajectories and integrating with multi-source urban big data(e.g.,street view imagery,remote sensing,and socio-economic data)across the built,natural,and social dimensions,The findings uncover that road density has the greatest impact on RI,and social variables(e.g.,population density and housing price)and natural variables(e.g.,slope and humidity)all make notable impact on outdoor running.Despite these findings,the impact of environmental variables likely change across different regions due to disparate regional construction and micro-environments,and those specific impacts as well as optimal thresholds also alter.Therefore,construction of healthy cities should take the whole urban environment into account and adapt to local conditions.This study provides a comprehensive evaluation on the influencing variables of healthy vitality and guides sustainable urban planning for creating running-friendly cities.展开更多
China’s Five-Year Plans balance stability and market vitality,o#ering a forward-looking model for social progress and economic transformation China’s Five-Year Plans(FYPs)represent a rare combination of strategic fo...China’s Five-Year Plans balance stability and market vitality,o#ering a forward-looking model for social progress and economic transformation China’s Five-Year Plans(FYPs)represent a rare combination of strategic foresight and adaptive governance.Over the past 70 years,this planning mechanism has served as both a compass and a roadmap,allowing China not only to stay true to its long-term objectives but also to recalibrate policies in response to evolving domestic and international environments.展开更多
The effects of the built environment factors on urban vitality have attracted wide attention in the urban planning fields in recent years,but few studies have considered the variables’relative importance and their no...The effects of the built environment factors on urban vitality have attracted wide attention in the urban planning fields in recent years,but few studies have considered the variables’relative importance and their nonlinear effects on urban vitality.Taking a Chinese metropolis—Hangzhou as a case study,this study applied the gradient boosting decision tree(GBDT)model to explore the nonlinear effects of the 5D factors of the urban built environment on urban social vitality and economic vitality and the importance of variables.The results show that the GBDT model has better goodness of fit than the traditional ordinary least squares(OLS)regression in the urban vitality models.The urban built environment plays an important role in affecting urban vitality,while built environment designs witness the most important effect.Specifically,the density of shopping facilities,medical facilities,and road networks are the most important factors affecting urban social vitality,while road network density,destination accessibility,and population density play the most important roles in affecting urban economic vitality.Finally,the urban built environment factors have nonlinear threshold effects on both urban economic and social vitality in Hangzhou,with differing nonlinear response patterns observed between social and economic dimensions.展开更多
The non-contact vital signs measurement technology based on millimeter wave radar has important medical value and unique advantages.However,because of its weak vibration characteristics,wide range of values,and the pr...The non-contact vital signs measurement technology based on millimeter wave radar has important medical value and unique advantages.However,because of its weak vibration characteristics,wide range of values,and the presence of respiratory harmonics and irrelevant motion interference in the detection signal,it is still difficult to perform a robust extraction in real time.To solve the above problems,the adaptive extraction of heart rates with a wide range of distribution is summarized as a multi-scale detection problem,and the distinction between heartbeat features and other irrelevant body motion features is summarized as a feature attention problem.Then,multi-scale detection module and heart rate feature attention module are designed and combined into a basic network module to build a heart rate extraction neural network.Through experiments based on properly designed datasets,a reasonable parameter design of the module is first explored.Experimental results show that in the signal data with unrelated motion data interference,average absolute error of the proposed method model for heart rate extraction can reach 1.87 beats/min,and average relative accuracy can reach 97.51%.展开更多
The deep sea holds vital resources and spatial potential for future human survival and development,reflecting the common interests and concerns of all mankind.Amidst unprecedented global transformations in a hundred y...The deep sea holds vital resources and spatial potential for future human survival and development,reflecting the common interests and concerns of all mankind.Amidst unprecedented global transformations in a hundred years,the deep sea has emerged as a critical area of international competition and serves as a new frontier for resource extraction,a strategic space for military competition,and a contested space for great power rivalry and rule-making.展开更多
Selenium(Se),an essential micronutrient among the 15 vital elements required for human physiology,exerts its biological functions primarily through its incorporation into selenoproteins.To date,approximately 25 seleno...Selenium(Se),an essential micronutrient among the 15 vital elements required for human physiology,exerts its biological functions primarily through its incorporation into selenoproteins.To date,approximately 25 selenoproteins have been characterized in mammalian systems,including glutathione peroxidase(GPX),thioredoxin reductase(TrxR),and iodothyronine deiodinases(DIOs),all of which exhibit indispensable physiological functions.展开更多
OBJECTIVE:To uncover the biological foundation of the prevailing TCM syndrome in individuals with Esophageal squamous cell carcinoma(ESCC),Zhengxu Xieshi(ZXXS),which is characterized by a deficiency in vital Qi and an...OBJECTIVE:To uncover the biological foundation of the prevailing TCM syndrome in individuals with Esophageal squamous cell carcinoma(ESCC),Zhengxu Xieshi(ZXXS),which is characterized by a deficiency in vital Qi and an excess in evil Qi.METHODS:We investigated shifts in vital Qi by quantifying systemic metabolic changes in the peripheral blood.Serum metabolomic profiling was conducted on the ESCC cohort 1 along with a matched healthy control cohort.Additionally,we assessed changes in evil Qi by examining metabolic perturbations in ESCC tissues.This analysis involved metabolomic and proteomic surveys of ESCC tissues and paired normal adjacent tissues as controls in an independent ESCC cohort 2.RESULTS:Serum metabolomic profiling highlighted the prevalent downregulation of differentially expressed metabolites in patient sera,in contrast to the upregulation observed in ESCC tissues,compared to their respective controls.Remarkably,the group of differential metabolites in the ESCC tissues was predominantly composed of amino acids.Thus,we focused on amino acid metabolism.Our integrative analysis showed the downregulation of a significant majority of disturbed amino acids in patient sera relative to the upregulation of an overwhelming proportion of perturbed amino acids within ESCC tissues.Enrichment analysis of these amino acids revealed seven metabolic pathways that contribute to the metabolism of antioxidants,energy intermediates,and biosynthetic precursors.Interestingly,these pathways displayed attenuation in patient sera but augmentation in ESCC tissues.Similarly,the proteomic data confirmed the activation of these pathways in ESCC tissues.CONCLUSION:This study presents a new perspective on the prevalence of ZXXS syndrome in patients with ESCC,contextualized within the realm of metabolic reprogramming.Specifically,diminished amino acid metabolism in the circulating blood corresponds to a deficiency in vital Qi.Conversely,hyperactive amino acid metabolism in ESCC tissues signifies an augmentation of local evil Qi.These findings hold potential to enrich the current medical framework and offer a deeper understanding of ESCC management by integrating the principles of ZXXS syndrome.展开更多
Inside the China Pavilion at Expo 2025 Osaka,Kansai,Japan,a cultural feast steeped in Liaoning’s history and brimming with its innovative spirit is unfolding.Under the banner“Poetic landscapes,Boundless vitality”,L...Inside the China Pavilion at Expo 2025 Osaka,Kansai,Japan,a cultural feast steeped in Liaoning’s history and brimming with its innovative spirit is unfolding.Under the banner“Poetic landscapes,Boundless vitality”,Liaoning Week employs intangible heritage showcases,live performances and exhibitions to reveal the province’s distinctive cultural charm.展开更多
The Institute of Soil Science(ISS)located at Nanjing is an academic community directly affiliated with the Chinese Academy of Sciences(CAS).Being the cradle,research center,and talent highland of modern soil science i...The Institute of Soil Science(ISS)located at Nanjing is an academic community directly affiliated with the Chinese Academy of Sciences(CAS).Being the cradle,research center,and talent highland of modern soil science in China,the institute is committed to promoting the development of soil science and to solving vital problems facing agricultural development,ecological conservation,and environmental protection.展开更多
文摘Ulsan port is the hugest industry-oriented port in South Korea. It has the third highest traffic volume of cargo, and also it has the most liquid bulk in Korea. However, on account of thoughtless development, there are other cases like Ulsan port that liquid cargo and general cargo are simultaneously handled. The demurrage ratio takes up to 12.5% of probability on average. In 2010, it has less room at berths for liquid bulk than general cargo and it totally has 107% of processing ratio (throughput). This indicates that Ulsan port concentrates on liquid cargo more than general cargo depending on the characteristics of the port. This research suggests the effects as alternatives for efficiency and effectivity at both ports, Ulsan port and Pohang port in the case that the general cargo handled in Ulsan port is relocated to Pohang port in terms of the characteristics of products which Pohang port and its hinterland the most focused on. Namely, we estimate volume of relocated volume suitable for relocation in assumption that volume handled in Ulsan port is relocated to Pohang port scenario by scenario, analyze the effects of relocated volume, and suggest alternatives for vitalizing Ulsan port.
基金supported by the National Natural Science Foundation of China(82170941 and 82370948 to Lu Zhang,82071110 and 82230029 to Zhi Chen)the National Key R&D Program of China(2018YFC1105100)。
文摘Pulpotomy,which belongs to vital pulp therapy,has become a strategy for managing pulpitis in recent decades.This minimally invasive treatment reflects the recognition of preserving healthy dental pulp and optimizing long-term patient-centered outcomes.Pulpotomy is categorized into partial pulpotomy(PP),the removal of a partial segment of the coronal pulp tissue,and full pulpotomy(FP),the removal of whole coronal pulp,which is followed by applying the biomaterials onto the remaining pulp tissue and ultimately restoring the tooth.Procedural decisions for the amount of pulp tissue removal or retention depend on the diagnostic of pulp vitality,the overall treatment plan,the patient’s general health status,and pulp inflammation reassessment during operation.This statement represents the consensus of an expert committee convened by the Society of Cariology and Endodontics,Chinese Stomatological Association.It addresses the current evidence to support the application of pulpotomy as a potential alternative to root canal treatment(RCT)on mature permanent teeth with pulpitis from a biological basis,the development of capping biomaterial,and the diagnostic considerations to evidence-based medicine.This expert statement intends to provide a clinical protocol of pulpotomy,which facilitates practitioners in choosing the optimal procedure and increasing their confidence in this rapidly evolving field.
文摘Open government-enterprise communication lies behind Qingdao’s success in attracting German investment.Aconducive business environment is crucial for stimulating economic vitality and driving high-quality development.
文摘Objective: To assess the impact of preoperative psychological interventions on the care of patients undergoing elective surgery. Methods: Ninety-two patients scheduled for elective surgery in the surgical department between August 2021 and August 2023 were selected and divided into groups using a random number table. The observation group received preoperative psychological interventions, while the reference group received standard preoperative care. Anxiety and depression scores, fear grading, vital signs, and self-efficacy levels were compared. Results: After the intervention, the anxiety and depression scores in the observation group were lower than those in the reference group, and the proportion of fear graded as Level I was higher. During the waiting period and 15 minutes before entering the operating room, vital sign levels in the observation group were lower than those in the reference group. Additionally, the self-efficacy scores of the observation group were significantly higher than those of the reference group (P < 0.05). Conclusion: Preoperative psychological interventions can alleviate negative emotions, stabilize preoperative vital signs, and significantly improve self-efficacy in patients undergoing elective surgery, demonstrating high feasibility for implementation.
文摘The blood-brain barrier(BBB),an intricate interface of the neurovascular unit,plays a vital role in maintaining the function of the central nervous system(CNS).The BBB interacts with various components,such as glial cells,circulating cells,exosomes,and hormones,to regulate communication between the CNS and the periphery[1].
基金National Natural Science Foundation of China,No.42171455The Hong Kong RGC Research Impact Fund,No.R5011-23The Hong Kong General Research Fund,No.15204121。
文摘Urban environments offer a wealth of opportunities for residents to respite from their hectic life.Outdoor running or jogging becomes increasingly popular of an option.Impacts of urban environments on outdoor running,despite some initial studies,remain underexplored.This study aims to establish an analytical framework that can holistically assess the urban environment on the healthy vitality of running.The proposed framework is applied to two modern Chinese cities,i.e.,Guangzhou and Shenzhen.We construct three interpretable random forest models to explore the non-linear relationship between environmental variables and running intensity(RI)through analyzing the runners'trajectories and integrating with multi-source urban big data(e.g.,street view imagery,remote sensing,and socio-economic data)across the built,natural,and social dimensions,The findings uncover that road density has the greatest impact on RI,and social variables(e.g.,population density and housing price)and natural variables(e.g.,slope and humidity)all make notable impact on outdoor running.Despite these findings,the impact of environmental variables likely change across different regions due to disparate regional construction and micro-environments,and those specific impacts as well as optimal thresholds also alter.Therefore,construction of healthy cities should take the whole urban environment into account and adapt to local conditions.This study provides a comprehensive evaluation on the influencing variables of healthy vitality and guides sustainable urban planning for creating running-friendly cities.
文摘China’s Five-Year Plans balance stability and market vitality,o#ering a forward-looking model for social progress and economic transformation China’s Five-Year Plans(FYPs)represent a rare combination of strategic foresight and adaptive governance.Over the past 70 years,this planning mechanism has served as both a compass and a roadmap,allowing China not only to stay true to its long-term objectives but also to recalibrate policies in response to evolving domestic and international environments.
基金National Social Science Foundation of China,No.20FJLB025National Natural Science Foundation of China,No.42471207,No.42471203Zhejiang Province Philosophy and Social Science Planning,Zhijiang Youth Special Project,24ZJQN118Y。
文摘The effects of the built environment factors on urban vitality have attracted wide attention in the urban planning fields in recent years,but few studies have considered the variables’relative importance and their nonlinear effects on urban vitality.Taking a Chinese metropolis—Hangzhou as a case study,this study applied the gradient boosting decision tree(GBDT)model to explore the nonlinear effects of the 5D factors of the urban built environment on urban social vitality and economic vitality and the importance of variables.The results show that the GBDT model has better goodness of fit than the traditional ordinary least squares(OLS)regression in the urban vitality models.The urban built environment plays an important role in affecting urban vitality,while built environment designs witness the most important effect.Specifically,the density of shopping facilities,medical facilities,and road networks are the most important factors affecting urban social vitality,while road network density,destination accessibility,and population density play the most important roles in affecting urban economic vitality.Finally,the urban built environment factors have nonlinear threshold effects on both urban economic and social vitality in Hangzhou,with differing nonlinear response patterns observed between social and economic dimensions.
基金the National Natural Science Foundation of China(No.51975361)。
文摘The non-contact vital signs measurement technology based on millimeter wave radar has important medical value and unique advantages.However,because of its weak vibration characteristics,wide range of values,and the presence of respiratory harmonics and irrelevant motion interference in the detection signal,it is still difficult to perform a robust extraction in real time.To solve the above problems,the adaptive extraction of heart rates with a wide range of distribution is summarized as a multi-scale detection problem,and the distinction between heartbeat features and other irrelevant body motion features is summarized as a feature attention problem.Then,multi-scale detection module and heart rate feature attention module are designed and combined into a basic network module to build a heart rate extraction neural network.Through experiments based on properly designed datasets,a reasonable parameter design of the module is first explored.Experimental results show that in the signal data with unrelated motion data interference,average absolute error of the proposed method model for heart rate extraction can reach 1.87 beats/min,and average relative accuracy can reach 97.51%.
文摘The deep sea holds vital resources and spatial potential for future human survival and development,reflecting the common interests and concerns of all mankind.Amidst unprecedented global transformations in a hundred years,the deep sea has emerged as a critical area of international competition and serves as a new frontier for resource extraction,a strategic space for military competition,and a contested space for great power rivalry and rule-making.
基金Financial support from the Science and Technology Innovation Program of Hunan Province(No.2022RC4044)。
文摘Selenium(Se),an essential micronutrient among the 15 vital elements required for human physiology,exerts its biological functions primarily through its incorporation into selenoproteins.To date,approximately 25 selenoproteins have been characterized in mammalian systems,including glutathione peroxidase(GPX),thioredoxin reductase(TrxR),and iodothyronine deiodinases(DIOs),all of which exhibit indispensable physiological functions.
基金Supported by Natural Science Foundation-funded Project:Establishment of Syndrome-Disease Warning System and Investigation of the Clinical Features and Evolution Patterns of Traditional Chinese Medicine Syndromes in Esophageal Cancer under Modern Medical Diagnosis and Treatment(2023YFC3503200,2023YFC3503201)Biological Basis of the Pathogenesis of Cancer Toxin in Traditional Chinese Medicine(2022YFC3500200,2022YFC3500202)+12 种基金Natural Science Foundation-funded Project:Mechanistic Study of the Nucleolar Methyltransferase Fibrillarin to Promote Neoplastic Growth of Esophageal Squamous Cell Carcinoma via Activating Nucleoside Synthesis(No.32170778)Mechanistic Study of Renal Cancer Neoplastic Growth Driven by Glucose Transporter 5-Mediated Fructose Metabolism Reprogramming(No.31970708)Mechanistic Study of Methionine Cycle Modulating the Growth of Esophageal Squamous Cell Carcinoma through"DNA Methylation-DNA Stability-p53/p21-cell Cycle"Pathway(No.82002953)the Antitumor Mechanism of Oleanolic Acid via Autophagy by Regulating Adenosine Monophosphate-Activated Protein Kinase-Mammalian Target of Rapamycin-Unc51 Like Kinase 1 Pathway and Inhibiting Purine Salvage Pathway(No.82004177)USP14 Cooperates with Ubiquitin C-Terminal Hydrolase L5 to Regulate Constitutive Photomorphogenic 9 Signalosome-mediated Programmed Death-Ligand 1 Deubiquitination and Promote Immune Evasion in Hepatocellular Carcinoma.(No.81972214)National Scientific and Technological Major Special Project of China:Shuang Huang Sheng Bai Oral Liquid:Efficacy and Safety Evaluation of Traditional Chinese Medicine Compound Based on Systems Biology Approaches(2019ZX09201004-002-013)A special clinical research initiative for the health business sponsored by the Shanghai Municipal Health Commission(No.202040155)Shanghai Municipal Science and Technology Commissions Special Biomedical Technology Support Plan(No.20S31904100)Shanghai"Science and Technology Innovation Action Plan"Medical Innovation Research Project--Shanghai Clinical Research Center of Traditional Chinese Medicine Oncology(21MC1930500)Shanghai 13th Five-Year Plan Key Specialty of Traditional Chinese Medicine Oncology(shslczdzk03701)Tracking Programme for Eastern Scholar at Shanghai Institutions of Higher LearningShanghai High-level Talent Leadership Programme of Traditional Chinese Medicine[ZY(2021-2023)-0403]Scientific Research Project of Industry Development Center of Shanghai University of Traditional Chinese Medicine(602076D)。
文摘OBJECTIVE:To uncover the biological foundation of the prevailing TCM syndrome in individuals with Esophageal squamous cell carcinoma(ESCC),Zhengxu Xieshi(ZXXS),which is characterized by a deficiency in vital Qi and an excess in evil Qi.METHODS:We investigated shifts in vital Qi by quantifying systemic metabolic changes in the peripheral blood.Serum metabolomic profiling was conducted on the ESCC cohort 1 along with a matched healthy control cohort.Additionally,we assessed changes in evil Qi by examining metabolic perturbations in ESCC tissues.This analysis involved metabolomic and proteomic surveys of ESCC tissues and paired normal adjacent tissues as controls in an independent ESCC cohort 2.RESULTS:Serum metabolomic profiling highlighted the prevalent downregulation of differentially expressed metabolites in patient sera,in contrast to the upregulation observed in ESCC tissues,compared to their respective controls.Remarkably,the group of differential metabolites in the ESCC tissues was predominantly composed of amino acids.Thus,we focused on amino acid metabolism.Our integrative analysis showed the downregulation of a significant majority of disturbed amino acids in patient sera relative to the upregulation of an overwhelming proportion of perturbed amino acids within ESCC tissues.Enrichment analysis of these amino acids revealed seven metabolic pathways that contribute to the metabolism of antioxidants,energy intermediates,and biosynthetic precursors.Interestingly,these pathways displayed attenuation in patient sera but augmentation in ESCC tissues.Similarly,the proteomic data confirmed the activation of these pathways in ESCC tissues.CONCLUSION:This study presents a new perspective on the prevalence of ZXXS syndrome in patients with ESCC,contextualized within the realm of metabolic reprogramming.Specifically,diminished amino acid metabolism in the circulating blood corresponds to a deficiency in vital Qi.Conversely,hyperactive amino acid metabolism in ESCC tissues signifies an augmentation of local evil Qi.These findings hold potential to enrich the current medical framework and offer a deeper understanding of ESCC management by integrating the principles of ZXXS syndrome.
文摘Inside the China Pavilion at Expo 2025 Osaka,Kansai,Japan,a cultural feast steeped in Liaoning’s history and brimming with its innovative spirit is unfolding.Under the banner“Poetic landscapes,Boundless vitality”,Liaoning Week employs intangible heritage showcases,live performances and exhibitions to reveal the province’s distinctive cultural charm.
文摘The Institute of Soil Science(ISS)located at Nanjing is an academic community directly affiliated with the Chinese Academy of Sciences(CAS).Being the cradle,research center,and talent highland of modern soil science in China,the institute is committed to promoting the development of soil science and to solving vital problems facing agricultural development,ecological conservation,and environmental protection.