This paper sought to surface visualizations of“older adult selves”(OAS)of junior college students studying development communication after an interaction with older adults in Bagac,Bataan in the Philippines.It was d...This paper sought to surface visualizations of“older adult selves”(OAS)of junior college students studying development communication after an interaction with older adults in Bagac,Bataan in the Philippines.It was done to figure out the ways by which such visualizations could be achieved through institutional efforts within an academic setting.Twenty-three students,mostly females who volunteered to participate in a reflection paper writing activity a week after the youth-older adult interaction,wrote their visions or projections of their life as older adults informed by their social exchanges with older adults in a rural community in the Philippines(Bagac,Bataan).The results indicated that an image of the well-connected older adult was shared across all narratives and it is characterized by youthfulness,openness and flexibility,and sense of accomplishment.Necessary conditions were drawn out from the data to help facilitate the fulfillment of such visions through the possible initiatives of St.Paul University Manila.展开更多
Abdominal aortic aneurysm is a common vascular disease that affects elderly population.Open surgical repair is regarded as the gold standard technique for treatment of abdominal aortic aneurysm,however,endovaseular an...Abdominal aortic aneurysm is a common vascular disease that affects elderly population.Open surgical repair is regarded as the gold standard technique for treatment of abdominal aortic aneurysm,however,endovaseular aneurysm repair has rapidly expanded since its first introduction in 1990s.As a less invasive technique,endovascular aneurysm repair has been confirmed to be an effective alternative to open surgical repair,especially in patients with co-morbid conditions.Computed tomography （CT） angiography is currently the preferred imaging modality for both preoperative planning and post-operative follow-up.2D CT images are complemented by a number of 3D reconstructions which enhance the diagnostic applications of CT angiography in both planning and follow-up of endovascular repair.CT has the disadvantage of high cummulative radiation dose,of particular concern in younger patients,since patients require regular imaging follow-ups after endovascular repair,thus,exposing patients to repeated radiation exposure for life.There is a trend to change from CT to ultrasound surveillance of endovascular aneurysm repair.Medical image visualizations demonstrate excellent morphological assessment of aneurysm and stent-grafts,but fail to provide hemodynamic changes caused by the complex stent-graft device that is implanted into the aorta.This article reviews the treatment options of abdominal aortic aneurysm,various image visualization tools,and follow-up procedures with use of different modalities including both imaging and computational fluid dynamics methods.Future directions to improve treatment outcomes in the follow-up of endovascular aneurysm repair are outlined.展开更多
The visualization of dynamic graphs is a challenging task owing to the various properties of the underlying relational data and the additional time-varying property.For sparse and small graphs,the most efficient appro...The visualization of dynamic graphs is a challenging task owing to the various properties of the underlying relational data and the additional time-varying property.For sparse and small graphs,the most efficient approach to such visualization is node-link diagrams,whereas for dense graphs with attached data,adjacency matrices might be the better choice.Because graphs can contain both properties,being globally sparse and locally dense,a combination of several visual metaphors as well as static and dynamic visualizations is beneficial.In this paper,a visually and algorithmically scalable approach that provides views and perspectives on graphs as interactively linked node-link and adjacency matrix visualizations is described.As the novelty of this technique,insights such as clusters or anomalies from one or several combined views can be used to influence the layout or reordering of the other views.Moreover,the importance of nodes and node groups can be detected,computed,and visualized by considering several layout and reordering properties in combination as well as different edge properties for the same set of nodes.As an additional feature set,an automatic identification of groups,clusters,and outliers is provided over time,and based on the visual outcome of the node-link and matrix visualizations,the repertoire of the supported layout and matrix reordering techniques is extended,and more interaction techniques are provided when considering the dynamics of the graph data.Finally,a small user experiment was conducted to investigate the usability of the proposed approach.The usefulness of the proposed tool is illustrated by applying it to a graph dataset,such as e co-authorships,co-citations,and a Comprehensible Perl Archive Network distribution.展开更多
Excessive unplanned urban growth leads to many vulnerabilities and impacts on urban environments to varying degrees. However, the majority of the extant literature focuses on the problems related to location and socio...Excessive unplanned urban growth leads to many vulnerabilities and impacts on urban environments to varying degrees. However, the majority of the extant literature focuses on the problems related to location and socioeconomic conditions, rather than vulnerability processes and related environmental degradation. This paper analyzes the scope of urban vulnerabilities for five rapidly urbanizing and highly-congested cities in the Kathmandu Valley, Nepal. First, the historic context of the Valley’s uncontrolled urbanization sets the scene. Second, the optic is narrowed to focus upon the geographical features of the resultant urbanized Valley landscape that includes spatial arrangements and of houses, population densities, road networks, vehicular densities, garbage problems, and available open spaces. Additionally, seismic vulnerabilities in the urban areas are also considering in this examination. Third, three-dimensional visualizations of selected urban locations are presented to differentiate between vulnerable and relatively safe locations. The intent of this research is to contribute to the methodological understanding of human/hazards interactions in rapidly urbanizing cities of the Third World, which share similar socioeconomic conditions and environmental con-texts.展开更多
Infill development has been seen as one of the solutions to urban challenges. However, it changes the dynamics and visual appearance of the neighborhood. As infill development usually requires the acceptance of local ...Infill development has been seen as one of the solutions to urban challenges. However, it changes the dynamics and visual appearance of the neighborhood. As infill development usually requires the acceptance of local stakeholders, their perceptions of the resulting intensified housing have a significant role. In this study, customized visualizations illustrating scenarios of infill development were made from the perspective of individual apartments in neighboring residential building. The usefulness of customized visualizations for local stakeholders was studied in the Tammela test area. A 3D virtual model of the existing environment was created. Models depicting the alternative infill buildings were added to the 3D model, which was used to create customized visualizations. These visualizations were utilized in the interviews of local stakeholders. The findings indicate that the customized visualizations help stakeholders conceptualize the impact, and plan and manage the infill development. Visualizations can also be seen as a tool for a resident-driven approach to intensifying housing.展开更多
Understanding which factors affect information visualization transparency continues to be one of the most relevant challenges in current research,especially since trust models how users build on the knowledge and use ...Understanding which factors affect information visualization transparency continues to be one of the most relevant challenges in current research,especially since trust models how users build on the knowledge and use it.This work extends the current body of research by studying the user’s subjective evaluation of the visualization transparency of hierarchical charts through the clarity,coverage,and look and feel dimensions.Additionally,we extend the user profile to better understand whether personality facets manifest a biasing effect on the trust-building process.Our results show that the data encodings do not affect how users perceive visualization transparency while controlling for personality factors.Regarding personality,the propensity to trust affects how they judge the clarity of a hierarchical chart.Our findings provide new insights into the research challenges of measuring trust and understanding the transparency of information visualization.Specifically,we explore how personality factors manifest in this trust-building relationship and user interaction within visualization systems.展开更多
Synaptic plasticity is essential for maintaining neuronal function in the central nervous system and serves as a critical indicator of the effects of neurodegenerative disease.Glaucoma directly impairs retinal ganglio...Synaptic plasticity is essential for maintaining neuronal function in the central nervous system and serves as a critical indicator of the effects of neurodegenerative disease.Glaucoma directly impairs retinal ganglion cells and their axons,leading to axonal transport dysfuntion,subsequently causing secondary damage to anterior or posterior ends of the visual system.Accordingly,recent evidence indicates that glaucoma is a degenerative disease of the central nervous system that causes damage throughout the visual pathway.However,the effects of glaucoma on synaptic plasticity in the primary visual cortex remain unclear.In this study,we established a mouse model of unilateral chronic ocular hypertension by injecting magnetic microbeads into the anterior chamber of one eye.We found that,after 4 weeks of chronic ocular hypertension,the neuronal somas were smaller in the superior colliculus and lateral geniculate body regions of the brain contralateral to the affected eye.This was accompanied by glial cell activation and increased expression of inflammatory factors.After 8 weeks of ocular hypertension,we observed a reduction in the number of excitatory and inhibitory synapses,dendritic spines,and activation of glial cells in the primary visual cortex contralateral to the affected eye.These findings suggest that glaucoma not only directly damages the retina but also induces alterations in synapses and dendritic spines in the primary visual cortex,providing new insights into the pathogenesis of glaucoma.展开更多
AIM:To compare the visual outcomes between bilateral implantation of Tecnis ZXR00 extended depth-of-focus(EDOF)intraocular lenses(IOLs)and mixed implantation of Tecnis ZXR00(EDOF)with Tecnis ZMB00(bifocal)IOLs.METHODS...AIM:To compare the visual outcomes between bilateral implantation of Tecnis ZXR00 extended depth-of-focus(EDOF)intraocular lenses(IOLs)and mixed implantation of Tecnis ZXR00(EDOF)with Tecnis ZMB00(bifocal)IOLs.METHODS:This postoperative cross-sectional study enrolled patients who underwent phacoemulsification combined with IOL implantation.Patients were divided into two groups:the bilateral ZXR00 group(ZXR00-only group)and the mixed IOL group(ZXR00+ZMB00 group).Primary outcome measures included uncorrected and corrected distance visual acuity(UDVA,CDVA),uncorrected and distance-corrected near visual acuity(UNVA,DCNVA),uncorrected and distance-corrected intermediate visual acuity(UIVA,DCIVA),and defocus curves.Secondary outcome measures were visual quality,spectacle independence,patient satisfaction,photic phenomena,and stereopsis.RESULTS:A total of 47 patients(94 eyes)were included,with 26 patients(11 males,15 females)in the ZXR00-only group(mean age:62.73±7.24y)and 21 patients(7 males,14 females)in the mixed group(mean age:65.71±9.16y).There was no statistically significant difference in age between the two groups(P=0.218).The mixed group showed significantly better binocular DCNVA compared to the ZXR00-only group(P=0.002).Defocus curve analysis revealed that the mixed group exhibited superior performance at−2.5 to−4.0 D but inferior performance at−0.5 and−1.5 D.Near stereoacuity was significantly poorer in the mixed group(Randot:5.589±0.744 vs 6.240±0.394 ln arcsec;Contour:4.966±0.973 vs 5.740±0.833 ln arcsec;both P<0.01).Both groups achieved high levels of spectacle independence and patient satisfaction,with no significant differences in photic phenomena or questionnaire scores.CONCLUSION:Mixed implantation of EDOF and bifocal IOLs improve near visual acuity but may compromise near stereopsis.This approach provides a viable option for patients prioritizing near vision;however,caution is recommended for individuals requiring fine stereoscopic vision for daily or professional tasks.展开更多
AIM:To identify early biomarkers associated with glaucomatous visual field(VF)progression in patients with normal-tension glaucoma(NTG).METHODS:This study included patients were divided into two groups based on diseas...AIM:To identify early biomarkers associated with glaucomatous visual field(VF)progression in patients with normal-tension glaucoma(NTG).METHODS:This study included patients were divided into two groups based on disease progression status.Tear samples were collected for proteomic analysis.Dataindependent acquisition(DIA)mass spectrometry combined with bioinformatic analyses was performed to identify and validate potential protein biomarkers for NTG progression.Additionally,differentially expressed proteins(DEPs)were evaluated using mediating effect models and receiver operating characteristic(ROC)curve analysis.RESULTS:A total of 19 patients(20 eyes)with NTG participated in this study,including 10 patients(4 males and 6 females;10 eyes)in the progression group with mean age of 67.70±9.03y and 10 patients(4 males and 6 females;10 eyes)in the non-progression group with mean age of 68.60±7.58y.A total of 158 significantly differentially expressed proteins were detected.UniProt database annotation identified 3 upregulated proteins and 12 downregulated proteins.Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that these DEPs were mainly enriched in pathways such as oocyte meiosis.Gene Ontology(GO)enrichment analysis revealed functional clusters related to cellular processes.Weighted gene coexpression network analysis(WGCNA)indicated that the core proteins were primarily involved in the neurodegenerationmultiple diseases pathway and cellular processes.Mediating effect analysis identified PRDX4(L)as a potential protein biomarker.ROC curve analysis showed that GNAI1 had the largest area under the curve(AUC=0.889).CONCLUSION:This study identifies 15 differentially expressed proteins in the tear fluid of NTG patients,including PRDX4(L).PRDX4(L)plays a key role in oxidative stress.展开更多
Urban green spaces have positive effects on both physical and mental wellbeing.However,few studies have focused on the trends and thresholds of the effects of different influences on restorative benefits when viewing ...Urban green spaces have positive effects on both physical and mental wellbeing.However,few studies have focused on the trends and thresholds of the effects of different influences on restorative benefits when viewing scenes differfeaturing plant communities.We measured subjective evaluations and objective physiological data from 44 participants who viewed images of plant communities in the yellow to green hue range to compare differences in restorative benefits among plant communities at different visual distances,as well as quantifying the influencing factors involved.The following results were found:(1)Coniferous and multi-layered plant communities were found to provide greater restorative benefits,and the restorative benefits grew with increasing visual distance.(2)Shape and color characteristics were significantly correlated with restorative benefits,but the relationship is not simply linear.(3)The restorative benefits were found to be greatest when crown proportion was 61.23%,trunk proportion ranged from 4.11%to 13.70%,and the value of color index value ranged from 25.44%to 35.56%;the restorative benefits gradually increased when sky proportion exceeded 12.95%-13.19%,the fractal dimension exceeded 1.62-1.67,and hue index exceeded 91.64°-95.67°;additionally,the restorative benefits decreased when the saturation index increased.This study provides a scientific basis for the construction and improvement of plant landscapes in urban green spaces.展开更多
AIM:To perform a bibliometric analysis of publications focusing on inflammatory mechanisms in glaucoma,thereby comprehensively understanding the current research status and identifying potential frontier directions fo...AIM:To perform a bibliometric analysis of publications focusing on inflammatory mechanisms in glaucoma,thereby comprehensively understanding the current research status and identifying potential frontier directions for future studies.METHODS:A systematic search was conducted in the Web of Science Core Collection(WoSCC)database to retrieve relevant literature published from January 1,2000,to August 31,2025(data accessed on September 12,2025).Multiple data visualization tools were employed to conduct in-depth analyses of the included publications,covering aspects such as publication quantity and quality,evolutionary trends of research hotspots,keyword cooccurrence networks,and collaborative patterns among countries/regions,institutions,and authors.RESULTS:A total of 3381 articles related to glaucoma inflammation were extracted from WoSCC.The analysis showed that the USA had the highest research output in this field(29.04%,n=982),followed by China(18.40%,n=622)and UK(6.01%,n=203).Based on citation frequency and burst intensity,the USA also ranked as the most influential country.Baudouin C and Sun X were identified as the most productive authors,while Journal of Glaucoma and Investigative Ophthalmology&Visual Science were the journals with the highest number of published relevant articles.Additionally,keyword analysis revealed that“neuroinflammation”,“retinal ganglion cells(RGCs)”,“pathophysiology”,and“traditional Chinese medicine”are emerging research hotspots in the field of immuneinflammatory responses in glaucoma.CONCLUSION:This study presents a comprehensive bibliometric overview of research on glaucoma-related inflammation,indicating that this field has received extensive scientific attention with a steady upward trend in research activity.Furthermore,it establishes a theoretical basis for the development of neuroinflammation-targeted therapeutic strategies for glaucoma and emphasizes the necessity of strengthening interdisciplinary collaboration to promote the clinical translation of research findings.展开更多
With the rapid development of generative artificial intelligence(GenAI),the task of story visualization,which transforms natural language narratives into coherent and consistent image sequences,has attracted growing r...With the rapid development of generative artificial intelligence(GenAI),the task of story visualization,which transforms natural language narratives into coherent and consistent image sequences,has attracted growing research attention.However,existing methods still face limitations in balancing multi-frame character consistency and generation efficiency,which restricts their feasibility for large-scale practical applications.To address this issue,this study proposes a modular cloud-based distributed system built on Stable Diffusion.By separating the character generation and story generation processes,and integratingmulti-feature control techniques,a cachingmechanism,and an asynchronous task queue architecture,the system enhances generation efficiency and scalability.The experimental design includes both automated and human evaluations of character consistency,performance testing,and multinode simulation.The results show that the proposed system outperforms the baseline model StoryGen in both CLIP-I and human evaluation metrics.In terms of performance,under the experimental environment of this study,dual-node deployment reduces average waiting time by approximately 19%,while the four-node simulation further reduces it by up to 65%.Overall,this study demonstrates the advantages of cloud-distributed GenAI in maintaining character consistency and reducing generation latency,highlighting its potential value inmulti-user collaborative story visualization applications.展开更多
Unmanned aerial vehicles(UAVs),especially quadcopters,have become indispensable in numerous industrial and scientific applications due to their flexibility,lowcost,and capability to operate in dynamic environments.Thi...Unmanned aerial vehicles(UAVs),especially quadcopters,have become indispensable in numerous industrial and scientific applications due to their flexibility,lowcost,and capability to operate in dynamic environments.This paper presents a complete design and implementation of a compact autonomous quadcopter capable of trajectory tracking,object detection,precision landing,and real-time telemetry via long-range communication protocols.The system integrates an onboard flight controller running real-time sensor fusion algorithms,a vision-based detection system on a companion single-board computer,and a telemetry unit using Long Range(LoRa)communication.Extensive flight tests were conducted to validate the system’s stability,communication range,and autonomous capabilities.Potential applications in law enforcement,agriculture,search and rescue,and environmental monitoring are also discussed.展开更多
Robust teleoperation in image-guided interventions faces critical challenges from latency,deformation,and the quasi-periodic nature of physiological motion.This paper presents a fully integrated,latency-aware visual s...Robust teleoperation in image-guided interventions faces critical challenges from latency,deformation,and the quasi-periodic nature of physiological motion.This paper presents a fully integrated,latency-aware visual servoing system leveraging stereo vision,hand–eye calibration,and learning-based prediction for motion-compensated teleoperation.The system combines a calibrated binocular camera setup,dual robotic arms,and a predictive control loop incorporating Long Short-Term Memory(LSTM)and Temporal Convolutional Network(TCN)models.Through experiments using both in vivo and phantom datasets,we quantitatively assess the prediction accuracy and motion-compensation performance of both models.Results show that TCNs deliver more stable and precise tracking,especially on regular trajectories,while LSTMs exhibit robustness under quasi-periodic dynamics.By matching prediction horizons to system latency,the approach significantly reduces peak and steady-state tracking errors,demonstrating practical feasibility for deploying prediction-augmented servoing in teleoperated surgical.展开更多
Neuromorphic visual perception,by emulating the efficient information processing mechanisms of biological vision systems and integrating innovations in materials and device architectures,offers novel solutions for art...Neuromorphic visual perception,by emulating the efficient information processing mechanisms of biological vision systems and integrating innovations in materials and device architectures,offers novel solutions for artificial intelligence sensing.For instance,the incorporation of low-dimensional materials(e.g.,quantum dots,carbon nanotubes,and two-dimensional materials)optimizes device optoelectronic properties,while the synergistic design of organic semiconductors and oxide materials balances flexibility with complementary metal-oxide-semiconductor(CMOS)compatibility.Representative neuromorphic devices such as memristors and neuromorphic transistors address traditional vision system bottlenecks via near-sensor and in-sensor architectures in data transmission latency and energy consumption,offering a new paradigm for highly integrated,energy-efficient real-time perception.However,critical challenges—including device non-uniformity caused by material interface defects,system instability induced by memristor conductance drift,and environmental adaptability under complex illumination—remain barriers to scalable applications.This review comprehensively examines neuromorphic visual perception devices from the perspectives of device structure,operational mechanisms,materials,and applications.It explores the pivotal roles of memristors,electrolyte-gated transistors,and other neuromorphic devices in optical signal perception and information processing,with a focus on their implementations in visual perception tasks and future prospects.展开更多
The visual system of teleost fish grows continuously,which is a useful model for studying regeneration of the central nervous system.Glial cells are key for this process,but their contribution is still not well define...The visual system of teleost fish grows continuously,which is a useful model for studying regeneration of the central nervous system.Glial cells are key for this process,but their contribution is still not well defined.We followed oligodendrocytes in the visual system of adult zebrafish during regeneration of the optic nerve at 6,24,and 72 hours post-lesion and at 7 and 14 days post-lesion via the sox10:tagRFP transgenic line and confocal microscopy.To understand the changes that these oligodendrocytes undergo during regeneration,we used Sox2 immunohistochemistry,a stem cell marker involved in oligodendrocyte differentiation.We also used the Click-iT™ Plus TUNEL assay to study cell death and a BrdU assay to determine cell proliferation.Before optic nerve crush,sox10:tagRFP oligodendrocytes are located in the retina,in the optic nerve head,and through all the entire optic nerve.Sox2-positive cells are present in the peripheral germinal zone,the mature retina,and the optic nerve.After optic nerve crush,sox10:tagRFP cells disappeared from the optic nerve crush zone,suggesting that they died,although they were not TUNEL positive.Concomitantly,the number of Sox2-positive cells increased around the crushed area,the optic nerve head,and the retina.Then,between 24 hours post-lesion and 14 days post-lesion,double sox10:tagRFP/Sox2-positive cells were detected in the retina,optic nerve head,and whole optic nerve,together with a proliferation response at 72 hours post-lesion.Our results confirm that a degenerating process may occur prior to regeneration.First,sox10:tagRFP oligodendrocytes that surround the degenerated axons stop wrapping them,change their“myelinating oligodendrocyte”morphology to a“nonmyelinating oligodendrocyte”morphology,and die.Then,residual oligodendrocyte progenitor cells in the optic nerve and retina proliferate and differentiate for the purpose of remyelination.As new axons arise from the surviving retinal ganglion cells,new sox10:tagRFP oligodendrocytes arise from residual oligodendrocyte progenitor cells to guide,nourish and myelinate them.Thus,oligodendrocytes play an active role in zebrafish axon regeneration and remyelination.展开更多
This study extends the self-propelled particle(SPP)model by incorporating a limited vision cone and local density sensing.The results reveal that clusters can simultaneously exhibit velocity polarization and spatial c...This study extends the self-propelled particle(SPP)model by incorporating a limited vision cone and local density sensing.The results reveal that clusters can simultaneously exhibit velocity polarization and spatial cohesion within specific ranges of vision angle and density threshold.The dependence of the dynamical features,including the order parameter and density variation,on the threshold and visual cone is investigated.Furthermore,a critical threshold is identified,which governs the transition between ordered and disordered states and is closely linked to density fluctuations and noise intensity.The clustering results show that the model is explained by the chasing mechanism responsible for cluster formation,density,and shape.These results may stimulate practical applications in swarm maneuvering.展开更多
Responsive colorimetric materials exhibit significant potential for application in fields such as smart food packaging and wound monitoring.The functional integration of pH-indicators with material carriers enables br...Responsive colorimetric materials exhibit significant potential for application in fields such as smart food packaging and wound monitoring.The functional integration of pH-indicators with material carriers enables breakthrough applications in nontraditional domains.In this study,we developed a novel material covalently grafted with a pH indicator that exhibited naked-eye pH-responsive color shifts.The covalent grafting of pH-responsive bromothymol blue onto carboxymethyl cellulose(CMC)was confirmed using advanced characterization techniques,including Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy.The pH-sensitive chromophore was covalently immobilized onto the CMC matrix through esterification,thereby establishing firm chemical conjugation.Moreover,a superior color-changing performance was achieved within several minutes in response to different pH values.The reusability and stability of this material offer distinct advantages over single-use pH test strips.pH-responsive colorimetric materials hold promise for efficient,noninvasive monitoring in intelligent packaging(food freshness),medical diagnostics(wound status,infections),biosensing,and environmental applications.展开更多
文摘This paper sought to surface visualizations of“older adult selves”(OAS)of junior college students studying development communication after an interaction with older adults in Bagac,Bataan in the Philippines.It was done to figure out the ways by which such visualizations could be achieved through institutional efforts within an academic setting.Twenty-three students,mostly females who volunteered to participate in a reflection paper writing activity a week after the youth-older adult interaction,wrote their visions or projections of their life as older adults informed by their social exchanges with older adults in a rural community in the Philippines(Bagac,Bataan).The results indicated that an image of the well-connected older adult was shared across all narratives and it is characterized by youthfulness,openness and flexibility,and sense of accomplishment.Necessary conditions were drawn out from the data to help facilitate the fulfillment of such visions through the possible initiatives of St.Paul University Manila.
文摘Abdominal aortic aneurysm is a common vascular disease that affects elderly population.Open surgical repair is regarded as the gold standard technique for treatment of abdominal aortic aneurysm,however,endovaseular aneurysm repair has rapidly expanded since its first introduction in 1990s.As a less invasive technique,endovascular aneurysm repair has been confirmed to be an effective alternative to open surgical repair,especially in patients with co-morbid conditions.Computed tomography （CT） angiography is currently the preferred imaging modality for both preoperative planning and post-operative follow-up.2D CT images are complemented by a number of 3D reconstructions which enhance the diagnostic applications of CT angiography in both planning and follow-up of endovascular repair.CT has the disadvantage of high cummulative radiation dose,of particular concern in younger patients,since patients require regular imaging follow-ups after endovascular repair,thus,exposing patients to repeated radiation exposure for life.There is a trend to change from CT to ultrasound surveillance of endovascular aneurysm repair.Medical image visualizations demonstrate excellent morphological assessment of aneurysm and stent-grafts,but fail to provide hemodynamic changes caused by the complex stent-graft device that is implanted into the aorta.This article reviews the treatment options of abdominal aortic aneurysm,various image visualization tools,and follow-up procedures with use of different modalities including both imaging and computational fluid dynamics methods.Future directions to improve treatment outcomes in the follow-up of endovascular aneurysm repair are outlined.
文摘The visualization of dynamic graphs is a challenging task owing to the various properties of the underlying relational data and the additional time-varying property.For sparse and small graphs,the most efficient approach to such visualization is node-link diagrams,whereas for dense graphs with attached data,adjacency matrices might be the better choice.Because graphs can contain both properties,being globally sparse and locally dense,a combination of several visual metaphors as well as static and dynamic visualizations is beneficial.In this paper,a visually and algorithmically scalable approach that provides views and perspectives on graphs as interactively linked node-link and adjacency matrix visualizations is described.As the novelty of this technique,insights such as clusters or anomalies from one or several combined views can be used to influence the layout or reordering of the other views.Moreover,the importance of nodes and node groups can be detected,computed,and visualized by considering several layout and reordering properties in combination as well as different edge properties for the same set of nodes.As an additional feature set,an automatic identification of groups,clusters,and outliers is provided over time,and based on the visual outcome of the node-link and matrix visualizations,the repertoire of the supported layout and matrix reordering techniques is extended,and more interaction techniques are provided when considering the dynamics of the graph data.Finally,a small user experiment was conducted to investigate the usability of the proposed approach.The usefulness of the proposed tool is illustrated by applying it to a graph dataset,such as e co-authorships,co-citations,and a Comprehensible Perl Archive Network distribution.
文摘Excessive unplanned urban growth leads to many vulnerabilities and impacts on urban environments to varying degrees. However, the majority of the extant literature focuses on the problems related to location and socioeconomic conditions, rather than vulnerability processes and related environmental degradation. This paper analyzes the scope of urban vulnerabilities for five rapidly urbanizing and highly-congested cities in the Kathmandu Valley, Nepal. First, the historic context of the Valley’s uncontrolled urbanization sets the scene. Second, the optic is narrowed to focus upon the geographical features of the resultant urbanized Valley landscape that includes spatial arrangements and of houses, population densities, road networks, vehicular densities, garbage problems, and available open spaces. Additionally, seismic vulnerabilities in the urban areas are also considering in this examination. Third, three-dimensional visualizations of selected urban locations are presented to differentiate between vulnerable and relatively safe locations. The intent of this research is to contribute to the methodological understanding of human/hazards interactions in rapidly urbanizing cities of the Third World, which share similar socioeconomic conditions and environmental con-texts.
基金The Academy of FinlandThe Centre of Excellence in Laser Scanning Research (CoE-LaSR) (272195)+5 种基金Research on Resident-Driven Infill Development Possibilities—Case Study in Urban Areas in Finland (REPSU) (255390)The Finnish Funding Agency for Innovation “A healthy building”—project (40250/14) The Aalto Energy Efficiency Research Programme (Light Energy—Efficient and Safe Traffic Environments project)The EUE project (2141226) The Aalto University doctoral program
文摘Infill development has been seen as one of the solutions to urban challenges. However, it changes the dynamics and visual appearance of the neighborhood. As infill development usually requires the acceptance of local stakeholders, their perceptions of the resulting intensified housing have a significant role. In this study, customized visualizations illustrating scenarios of infill development were made from the perspective of individual apartments in neighboring residential building. The usefulness of customized visualizations for local stakeholders was studied in the Tammela test area. A 3D virtual model of the existing environment was created. Models depicting the alternative infill buildings were added to the 3D model, which was used to create customized visualizations. These visualizations were utilized in the interviews of local stakeholders. The findings indicate that the customized visualizations help stakeholders conceptualize the impact, and plan and manage the infill development. Visualizations can also be seen as a tool for a resident-driven approach to intensifying housing.
基金reviewed and approved by The Ethics Commit-tee of Instituto Superior TécnicoThe reference number for thisapproval is 22/2021(CE-IST).
文摘Understanding which factors affect information visualization transparency continues to be one of the most relevant challenges in current research,especially since trust models how users build on the knowledge and use it.This work extends the current body of research by studying the user’s subjective evaluation of the visualization transparency of hierarchical charts through the clarity,coverage,and look and feel dimensions.Additionally,we extend the user profile to better understand whether personality facets manifest a biasing effect on the trust-building process.Our results show that the data encodings do not affect how users perceive visualization transparency while controlling for personality factors.Regarding personality,the propensity to trust affects how they judge the clarity of a hierarchical chart.Our findings provide new insights into the research challenges of measuring trust and understanding the transparency of information visualization.Specifically,we explore how personality factors manifest in this trust-building relationship and user interaction within visualization systems.
基金supported by the National Natural Science Foundation of China,No.82271115(to MY).
文摘Synaptic plasticity is essential for maintaining neuronal function in the central nervous system and serves as a critical indicator of the effects of neurodegenerative disease.Glaucoma directly impairs retinal ganglion cells and their axons,leading to axonal transport dysfuntion,subsequently causing secondary damage to anterior or posterior ends of the visual system.Accordingly,recent evidence indicates that glaucoma is a degenerative disease of the central nervous system that causes damage throughout the visual pathway.However,the effects of glaucoma on synaptic plasticity in the primary visual cortex remain unclear.In this study,we established a mouse model of unilateral chronic ocular hypertension by injecting magnetic microbeads into the anterior chamber of one eye.We found that,after 4 weeks of chronic ocular hypertension,the neuronal somas were smaller in the superior colliculus and lateral geniculate body regions of the brain contralateral to the affected eye.This was accompanied by glial cell activation and increased expression of inflammatory factors.After 8 weeks of ocular hypertension,we observed a reduction in the number of excitatory and inhibitory synapses,dendritic spines,and activation of glial cells in the primary visual cortex contralateral to the affected eye.These findings suggest that glaucoma not only directly damages the retina but also induces alterations in synapses and dendritic spines in the primary visual cortex,providing new insights into the pathogenesis of glaucoma.
文摘AIM:To compare the visual outcomes between bilateral implantation of Tecnis ZXR00 extended depth-of-focus(EDOF)intraocular lenses(IOLs)and mixed implantation of Tecnis ZXR00(EDOF)with Tecnis ZMB00(bifocal)IOLs.METHODS:This postoperative cross-sectional study enrolled patients who underwent phacoemulsification combined with IOL implantation.Patients were divided into two groups:the bilateral ZXR00 group(ZXR00-only group)and the mixed IOL group(ZXR00+ZMB00 group).Primary outcome measures included uncorrected and corrected distance visual acuity(UDVA,CDVA),uncorrected and distance-corrected near visual acuity(UNVA,DCNVA),uncorrected and distance-corrected intermediate visual acuity(UIVA,DCIVA),and defocus curves.Secondary outcome measures were visual quality,spectacle independence,patient satisfaction,photic phenomena,and stereopsis.RESULTS:A total of 47 patients(94 eyes)were included,with 26 patients(11 males,15 females)in the ZXR00-only group(mean age:62.73±7.24y)and 21 patients(7 males,14 females)in the mixed group(mean age:65.71±9.16y).There was no statistically significant difference in age between the two groups(P=0.218).The mixed group showed significantly better binocular DCNVA compared to the ZXR00-only group(P=0.002).Defocus curve analysis revealed that the mixed group exhibited superior performance at−2.5 to−4.0 D but inferior performance at−0.5 and−1.5 D.Near stereoacuity was significantly poorer in the mixed group(Randot:5.589±0.744 vs 6.240±0.394 ln arcsec;Contour:4.966±0.973 vs 5.740±0.833 ln arcsec;both P<0.01).Both groups achieved high levels of spectacle independence and patient satisfaction,with no significant differences in photic phenomena or questionnaire scores.CONCLUSION:Mixed implantation of EDOF and bifocal IOLs improve near visual acuity but may compromise near stereopsis.This approach provides a viable option for patients prioritizing near vision;however,caution is recommended for individuals requiring fine stereoscopic vision for daily or professional tasks.
基金Supported by The Eye Hospital of Wenzhou Medical University(No.KYQD20220304)The Fifth Batch of Provincial Ten Thousand Personnel Program Outstanding Talents Funding(No.474092204)+1 种基金Innovative Talents and Teams(2024)-The Fifth Batch of Funding Funds for Scientific and Technological Innovation Leading Talents Under the Provincial Ten Thousand Personnel Program(No.4240924003G)The Key R&D Program of Zhejiang(No.2022C03112).
文摘AIM:To identify early biomarkers associated with glaucomatous visual field(VF)progression in patients with normal-tension glaucoma(NTG).METHODS:This study included patients were divided into two groups based on disease progression status.Tear samples were collected for proteomic analysis.Dataindependent acquisition(DIA)mass spectrometry combined with bioinformatic analyses was performed to identify and validate potential protein biomarkers for NTG progression.Additionally,differentially expressed proteins(DEPs)were evaluated using mediating effect models and receiver operating characteristic(ROC)curve analysis.RESULTS:A total of 19 patients(20 eyes)with NTG participated in this study,including 10 patients(4 males and 6 females;10 eyes)in the progression group with mean age of 67.70±9.03y and 10 patients(4 males and 6 females;10 eyes)in the non-progression group with mean age of 68.60±7.58y.A total of 158 significantly differentially expressed proteins were detected.UniProt database annotation identified 3 upregulated proteins and 12 downregulated proteins.Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that these DEPs were mainly enriched in pathways such as oocyte meiosis.Gene Ontology(GO)enrichment analysis revealed functional clusters related to cellular processes.Weighted gene coexpression network analysis(WGCNA)indicated that the core proteins were primarily involved in the neurodegenerationmultiple diseases pathway and cellular processes.Mediating effect analysis identified PRDX4(L)as a potential protein biomarker.ROC curve analysis showed that GNAI1 had the largest area under the curve(AUC=0.889).CONCLUSION:This study identifies 15 differentially expressed proteins in the tear fluid of NTG patients,including PRDX4(L).PRDX4(L)plays a key role in oxidative stress.
基金funded by the National Natural Science Foundation of China(32471953)the Educational Department of Liaoning Province Key Research Project(LJ212410153073).
文摘Urban green spaces have positive effects on both physical and mental wellbeing.However,few studies have focused on the trends and thresholds of the effects of different influences on restorative benefits when viewing scenes differfeaturing plant communities.We measured subjective evaluations and objective physiological data from 44 participants who viewed images of plant communities in the yellow to green hue range to compare differences in restorative benefits among plant communities at different visual distances,as well as quantifying the influencing factors involved.The following results were found:(1)Coniferous and multi-layered plant communities were found to provide greater restorative benefits,and the restorative benefits grew with increasing visual distance.(2)Shape and color characteristics were significantly correlated with restorative benefits,but the relationship is not simply linear.(3)The restorative benefits were found to be greatest when crown proportion was 61.23%,trunk proportion ranged from 4.11%to 13.70%,and the value of color index value ranged from 25.44%to 35.56%;the restorative benefits gradually increased when sky proportion exceeded 12.95%-13.19%,the fractal dimension exceeded 1.62-1.67,and hue index exceeded 91.64°-95.67°;additionally,the restorative benefits decreased when the saturation index increased.This study provides a scientific basis for the construction and improvement of plant landscapes in urban green spaces.
基金Supported by the National Natural Science Foundation of China(No.82074500)Beijing Natural Science Foundation(No.7252273)+2 种基金CACMS Innovation Fund(No.CI2021A02605)Administration of Traditional Chinese Medicine of Zhejiang Province(No.2024ZR029)Science and Technology Program of Wenzhou City(No.Y2023210).
文摘AIM:To perform a bibliometric analysis of publications focusing on inflammatory mechanisms in glaucoma,thereby comprehensively understanding the current research status and identifying potential frontier directions for future studies.METHODS:A systematic search was conducted in the Web of Science Core Collection(WoSCC)database to retrieve relevant literature published from January 1,2000,to August 31,2025(data accessed on September 12,2025).Multiple data visualization tools were employed to conduct in-depth analyses of the included publications,covering aspects such as publication quantity and quality,evolutionary trends of research hotspots,keyword cooccurrence networks,and collaborative patterns among countries/regions,institutions,and authors.RESULTS:A total of 3381 articles related to glaucoma inflammation were extracted from WoSCC.The analysis showed that the USA had the highest research output in this field(29.04%,n=982),followed by China(18.40%,n=622)and UK(6.01%,n=203).Based on citation frequency and burst intensity,the USA also ranked as the most influential country.Baudouin C and Sun X were identified as the most productive authors,while Journal of Glaucoma and Investigative Ophthalmology&Visual Science were the journals with the highest number of published relevant articles.Additionally,keyword analysis revealed that“neuroinflammation”,“retinal ganglion cells(RGCs)”,“pathophysiology”,and“traditional Chinese medicine”are emerging research hotspots in the field of immuneinflammatory responses in glaucoma.CONCLUSION:This study presents a comprehensive bibliometric overview of research on glaucoma-related inflammation,indicating that this field has received extensive scientific attention with a steady upward trend in research activity.Furthermore,it establishes a theoretical basis for the development of neuroinflammation-targeted therapeutic strategies for glaucoma and emphasizes the necessity of strengthening interdisciplinary collaboration to promote the clinical translation of research findings.
文摘With the rapid development of generative artificial intelligence(GenAI),the task of story visualization,which transforms natural language narratives into coherent and consistent image sequences,has attracted growing research attention.However,existing methods still face limitations in balancing multi-frame character consistency and generation efficiency,which restricts their feasibility for large-scale practical applications.To address this issue,this study proposes a modular cloud-based distributed system built on Stable Diffusion.By separating the character generation and story generation processes,and integratingmulti-feature control techniques,a cachingmechanism,and an asynchronous task queue architecture,the system enhances generation efficiency and scalability.The experimental design includes both automated and human evaluations of character consistency,performance testing,and multinode simulation.The results show that the proposed system outperforms the baseline model StoryGen in both CLIP-I and human evaluation metrics.In terms of performance,under the experimental environment of this study,dual-node deployment reduces average waiting time by approximately 19%,while the four-node simulation further reduces it by up to 65%.Overall,this study demonstrates the advantages of cloud-distributed GenAI in maintaining character consistency and reducing generation latency,highlighting its potential value inmulti-user collaborative story visualization applications.
文摘Unmanned aerial vehicles(UAVs),especially quadcopters,have become indispensable in numerous industrial and scientific applications due to their flexibility,lowcost,and capability to operate in dynamic environments.This paper presents a complete design and implementation of a compact autonomous quadcopter capable of trajectory tracking,object detection,precision landing,and real-time telemetry via long-range communication protocols.The system integrates an onboard flight controller running real-time sensor fusion algorithms,a vision-based detection system on a companion single-board computer,and a telemetry unit using Long Range(LoRa)communication.Extensive flight tests were conducted to validate the system’s stability,communication range,and autonomous capabilities.Potential applications in law enforcement,agriculture,search and rescue,and environmental monitoring are also discussed.
基金Support by Sichuan Science and Technology Program[2023YFSY0026,2023YFH0004]Guangzhou Huashang University[2024HSZD01,HS2023JYSZH01].
文摘Robust teleoperation in image-guided interventions faces critical challenges from latency,deformation,and the quasi-periodic nature of physiological motion.This paper presents a fully integrated,latency-aware visual servoing system leveraging stereo vision,hand–eye calibration,and learning-based prediction for motion-compensated teleoperation.The system combines a calibrated binocular camera setup,dual robotic arms,and a predictive control loop incorporating Long Short-Term Memory(LSTM)and Temporal Convolutional Network(TCN)models.Through experiments using both in vivo and phantom datasets,we quantitatively assess the prediction accuracy and motion-compensation performance of both models.Results show that TCNs deliver more stable and precise tracking,especially on regular trajectories,while LSTMs exhibit robustness under quasi-periodic dynamics.By matching prediction horizons to system latency,the approach significantly reduces peak and steady-state tracking errors,demonstrating practical feasibility for deploying prediction-augmented servoing in teleoperated surgical.
基金supported by Post-Moore Major Project of the National Natural Science Foundation of China(Grant No.92364204)Zhejiang Province introduces and cultivates leading innovation and entrepreneurship teams(Grant No.2023R01011)+1 种基金Zhejiang Provincial Natural Science Foundation of China(Grant No.LMS25F040005)the Key R&D Program of Zhejiang(Grant No.2024SSYS0042)。
文摘Neuromorphic visual perception,by emulating the efficient information processing mechanisms of biological vision systems and integrating innovations in materials and device architectures,offers novel solutions for artificial intelligence sensing.For instance,the incorporation of low-dimensional materials(e.g.,quantum dots,carbon nanotubes,and two-dimensional materials)optimizes device optoelectronic properties,while the synergistic design of organic semiconductors and oxide materials balances flexibility with complementary metal-oxide-semiconductor(CMOS)compatibility.Representative neuromorphic devices such as memristors and neuromorphic transistors address traditional vision system bottlenecks via near-sensor and in-sensor architectures in data transmission latency and energy consumption,offering a new paradigm for highly integrated,energy-efficient real-time perception.However,critical challenges—including device non-uniformity caused by material interface defects,system instability induced by memristor conductance drift,and environmental adaptability under complex illumination—remain barriers to scalable applications.This review comprehensively examines neuromorphic visual perception devices from the perspectives of device structure,operational mechanisms,materials,and applications.It explores the pivotal roles of memristors,electrolyte-gated transistors,and other neuromorphic devices in optical signal perception and information processing,with a focus on their implementations in visual perception tasks and future prospects.
基金supported by the Lanzadera TCUE and C2 program(Universidad de Salamanca)(to ASL)the Spanish National Research Council(CSIC)funded by the Junta de Castilla y León and co-financed by the European Regional Development Fund(ERDF“Europe drives our growth”):Internationalization Project“CL-EI-2021-08-IBFG Unit of Excellence”,Grant(PID2022-138478OA-100)funded by MICIU/AEI/10.13039/501100011033 and,by FEDER,UE(to MGM)+3 种基金Junta de Castilla y León(SA225P23)Gerencia Regional de Salud(2701/A1/2023)(to AV)the Plan Especial Grado Medicina(USAL)(to CPM)a Ramón y Cajal researcher:Grant RYC2021-033684-I funded by MICIU/AEI/10.13039/501100011033 and,by European Union NextGenerationEU/PRTR.
文摘The visual system of teleost fish grows continuously,which is a useful model for studying regeneration of the central nervous system.Glial cells are key for this process,but their contribution is still not well defined.We followed oligodendrocytes in the visual system of adult zebrafish during regeneration of the optic nerve at 6,24,and 72 hours post-lesion and at 7 and 14 days post-lesion via the sox10:tagRFP transgenic line and confocal microscopy.To understand the changes that these oligodendrocytes undergo during regeneration,we used Sox2 immunohistochemistry,a stem cell marker involved in oligodendrocyte differentiation.We also used the Click-iT™ Plus TUNEL assay to study cell death and a BrdU assay to determine cell proliferation.Before optic nerve crush,sox10:tagRFP oligodendrocytes are located in the retina,in the optic nerve head,and through all the entire optic nerve.Sox2-positive cells are present in the peripheral germinal zone,the mature retina,and the optic nerve.After optic nerve crush,sox10:tagRFP cells disappeared from the optic nerve crush zone,suggesting that they died,although they were not TUNEL positive.Concomitantly,the number of Sox2-positive cells increased around the crushed area,the optic nerve head,and the retina.Then,between 24 hours post-lesion and 14 days post-lesion,double sox10:tagRFP/Sox2-positive cells were detected in the retina,optic nerve head,and whole optic nerve,together with a proliferation response at 72 hours post-lesion.Our results confirm that a degenerating process may occur prior to regeneration.First,sox10:tagRFP oligodendrocytes that surround the degenerated axons stop wrapping them,change their“myelinating oligodendrocyte”morphology to a“nonmyelinating oligodendrocyte”morphology,and die.Then,residual oligodendrocyte progenitor cells in the optic nerve and retina proliferate and differentiate for the purpose of remyelination.As new axons arise from the surviving retinal ganglion cells,new sox10:tagRFP oligodendrocytes arise from residual oligodendrocyte progenitor cells to guide,nourish and myelinate them.Thus,oligodendrocytes play an active role in zebrafish axon regeneration and remyelination.
基金Project supported by the Postgraduate Research&Practice Innovation Program of Jiangsu Province(Grant No.KYCX240139)funded by the Youth Independent Innovation Fund of PLA Army Engineering University(Grant No.KYJBJKQTZQ23006)。
文摘This study extends the self-propelled particle(SPP)model by incorporating a limited vision cone and local density sensing.The results reveal that clusters can simultaneously exhibit velocity polarization and spatial cohesion within specific ranges of vision angle and density threshold.The dependence of the dynamical features,including the order parameter and density variation,on the threshold and visual cone is investigated.Furthermore,a critical threshold is identified,which governs the transition between ordered and disordered states and is closely linked to density fluctuations and noise intensity.The clustering results show that the model is explained by the chasing mechanism responsible for cluster formation,density,and shape.These results may stimulate practical applications in swarm maneuvering.
基金financially supported by the National Natural Science Foundation of China(No.52303209)the“Lingyan”Program of Zhejiang Province(No.2024C03076)+1 种基金Zhejiang University K.P.Chao’s High Technology Development Foundationthe generous support provided by the joint research fund from the Shaoxing Institute of Zhejiang University and Shaoxing Maternity and Child Health Care Hospital。
文摘Responsive colorimetric materials exhibit significant potential for application in fields such as smart food packaging and wound monitoring.The functional integration of pH-indicators with material carriers enables breakthrough applications in nontraditional domains.In this study,we developed a novel material covalently grafted with a pH indicator that exhibited naked-eye pH-responsive color shifts.The covalent grafting of pH-responsive bromothymol blue onto carboxymethyl cellulose(CMC)was confirmed using advanced characterization techniques,including Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy.The pH-sensitive chromophore was covalently immobilized onto the CMC matrix through esterification,thereby establishing firm chemical conjugation.Moreover,a superior color-changing performance was achieved within several minutes in response to different pH values.The reusability and stability of this material offer distinct advantages over single-use pH test strips.pH-responsive colorimetric materials hold promise for efficient,noninvasive monitoring in intelligent packaging(food freshness),medical diagnostics(wound status,infections),biosensing,and environmental applications.
