BACKGROUND Children with critical acute abdominal conditions often undergo intestinal stoma surgery.AIM To explore the impact of a visual mobile terminal-based extended care model on caregiver competence for children ...BACKGROUND Children with critical acute abdominal conditions often undergo intestinal stoma surgery.AIM To explore the impact of a visual mobile terminal-based extended care model on caregiver competence for children with enterostomies.METHODS One hundred twenty children with enterostomies and their caregivers in a children's hospital in Beijing were divided into a control group and a study group.The control group(60 cases)received traditional telephone follow-up for continuity of care,while the study group(60 cases)used a visualization mobile terminal-based care model.The incidence of stoma-related complications,caregiver burden scale,and competence scores of children with stoma were compared between the two groups.RESULTS The primary caregiver burden score in the study group(37.22±3.17)was significantly lower than that in the control group(80.00±4.47),and the difference was statistically significant(P<0.05).Additionally,the caregiving ability score of the study group(172.08±3.49)was significantly higher than that of the control group(117.55±4.28;P<0.05).The total incidence of complications in the study group(11.7%,7/60)was significantly lower compared to the control group(33.3%,20/60;χ2=8.086,P=0.004).CONCLUSION The visual mobile terminal-based care model reduces caregiver burden,improves home care ability,lowers the incidence of complications and readmission rates,and supports successful second-stage reduction surgery for children with enterostomies.展开更多
AIM：To investigate the association between tear film break up time（TBUT）and blinking interval in visual display terminal（VDT）users.METHODS：Nine hundred and thirty VDT users underwent dry eye testing,and function...AIM：To investigate the association between tear film break up time（TBUT）and blinking interval in visual display terminal（VDT）users.METHODS：Nine hundred and thirty VDT users underwent dry eye testing,and functional visual acuity（FVA）test.The blinking interval during FVA was compared with TBUT.Subjects with longer blinking interval than TBUT were considered as unstable tear film.Logistic regression analysis revealed the risk factors for unstable tear group.RESULTS：Among 930 workers,858 subjects（92.3%）participated in this study.Almost 80% of the subjects were categorized into the unstable tear group.Unstable tear group has significantly lower Schirmer values and TBUT（17.5±11.6 vs 21.1±11.5 mm,3.7±2.6 vs 5.7±2.7s,both P〈0.001）.There were no significant differences in epithelial staining or severity of symptoms.Logistic regression showed that over 40y was a risk for being unstable tear group[odds ratio（OR）=1.53;95%confidence interval（CI）=1.06-2.20].Contact lens use was protective factor for being in the unstable tear group（OR=0.37;95%CI=0.26-0.53）.CONCLUSION：Subjects with shorter TBUT than blinking interval are prevalent among VDT users.Subjects over the age of 40 shows an increased risk for unstable tear film.展开更多
AIM:To evaluate 3%diquafosol ophthalmic solution on ocular surface parameters and the alterations of lipid and muco-aqueous layer in tear film of patients with visual display terminal(VDT)-associated dry eye disease(D...AIM:To evaluate 3%diquafosol ophthalmic solution on ocular surface parameters and the alterations of lipid and muco-aqueous layer in tear film of patients with visual display terminal(VDT)-associated dry eye disease(DED).METHODS:This study included patients with VDTassociated DED.It was a prospective single-arm interventional clinical trial.Patients were provided with 3%diquafosol ophthalmic solution for 3mo and were followed up in 1,2 and 3mo after treatment.Tear breakup time(TBUT),ocular surface staining score,and ocular surface disease index(OSDI)score were ocular surface characteristics.Lipid layer thickness(LLT),tear meniscus height(TMH),and mucin mRNA expression levels(MUC1,MUC4,MUC5AC,MUC16,and MUC20)were used to measure changes in the tear film.The LipiView interferometer was used to measure the partial blink rate(PBR).RESULTS:Sixty-eight eyes of 68 participants(54 females;mean age 25.12±4.10y;mean spherical equivalent-4.35±2.69 D)were enrolled.Compared with the pre-treatment,OSDI scores and TBUT improved significantly at all follow-up time points(all P<0.01),and TMH increased significantly at 1 and 3mo(P<0.01,P<0.001,respectively).Conjunctival lissamine green staining improved only at 2mo(P<0.05),while corneal fluorescein staining showed no significant changes.Overall LLT remained unchanged,but the PBR<1 subgroup exhibited significant LLT elevation at 3mo(P<0.05),unlike the PBR=1 subgroup.Conjunctival mRNA expression of MUC1,MUC5AC,MUC16,and MUC20 was significantly upregulated at 1 and 3mo(all P<0.01),and MUC4 expression increased significantly only at 1mo(P<0.001).CONCLUSION:In patients with VDT-associated DED,3%diquafosol ophthalmic solution dramatically reduced symptoms and enhanced tear film stability by promoting ocular surface muco-aqueous secretion.Patients with better blinking habits(PBR<1)demonstrate greater LLT improvement than those with poorer habits.展开更多
基金Supported by Project of the Health Bureau of the Logistics and Security Department of the Central Military Commission,No.145BHQ090003076XMilitary Family Planning Special Fund,No.21JSZ18.
文摘BACKGROUND Children with critical acute abdominal conditions often undergo intestinal stoma surgery.AIM To explore the impact of a visual mobile terminal-based extended care model on caregiver competence for children with enterostomies.METHODS One hundred twenty children with enterostomies and their caregivers in a children's hospital in Beijing were divided into a control group and a study group.The control group(60 cases)received traditional telephone follow-up for continuity of care,while the study group(60 cases)used a visualization mobile terminal-based care model.The incidence of stoma-related complications,caregiver burden scale,and competence scores of children with stoma were compared between the two groups.RESULTS The primary caregiver burden score in the study group(37.22±3.17)was significantly lower than that in the control group(80.00±4.47),and the difference was statistically significant(P<0.05).Additionally,the caregiving ability score of the study group(172.08±3.49)was significantly higher than that of the control group(117.55±4.28;P<0.05).The total incidence of complications in the study group(11.7%,7/60)was significantly lower compared to the control group(33.3%,20/60;χ2=8.086,P=0.004).CONCLUSION The visual mobile terminal-based care model reduces caregiver burden,improves home care ability,lowers the incidence of complications and readmission rates,and supports successful second-stage reduction surgery for children with enterostomies.
文摘AIM：To investigate the association between tear film break up time（TBUT）and blinking interval in visual display terminal（VDT）users.METHODS：Nine hundred and thirty VDT users underwent dry eye testing,and functional visual acuity（FVA）test.The blinking interval during FVA was compared with TBUT.Subjects with longer blinking interval than TBUT were considered as unstable tear film.Logistic regression analysis revealed the risk factors for unstable tear group.RESULTS：Among 930 workers,858 subjects（92.3%）participated in this study.Almost 80% of the subjects were categorized into the unstable tear group.Unstable tear group has significantly lower Schirmer values and TBUT（17.5±11.6 vs 21.1±11.5 mm,3.7±2.6 vs 5.7±2.7s,both P〈0.001）.There were no significant differences in epithelial staining or severity of symptoms.Logistic regression showed that over 40y was a risk for being unstable tear group[odds ratio（OR）=1.53;95%confidence interval（CI）=1.06-2.20].Contact lens use was protective factor for being in the unstable tear group（OR=0.37;95%CI=0.26-0.53）.CONCLUSION：Subjects with shorter TBUT than blinking interval are prevalent among VDT users.Subjects over the age of 40 shows an increased risk for unstable tear film.
文摘AIM:To evaluate 3%diquafosol ophthalmic solution on ocular surface parameters and the alterations of lipid and muco-aqueous layer in tear film of patients with visual display terminal(VDT)-associated dry eye disease(DED).METHODS:This study included patients with VDTassociated DED.It was a prospective single-arm interventional clinical trial.Patients were provided with 3%diquafosol ophthalmic solution for 3mo and were followed up in 1,2 and 3mo after treatment.Tear breakup time(TBUT),ocular surface staining score,and ocular surface disease index(OSDI)score were ocular surface characteristics.Lipid layer thickness(LLT),tear meniscus height(TMH),and mucin mRNA expression levels(MUC1,MUC4,MUC5AC,MUC16,and MUC20)were used to measure changes in the tear film.The LipiView interferometer was used to measure the partial blink rate(PBR).RESULTS:Sixty-eight eyes of 68 participants(54 females;mean age 25.12±4.10y;mean spherical equivalent-4.35±2.69 D)were enrolled.Compared with the pre-treatment,OSDI scores and TBUT improved significantly at all follow-up time points(all P<0.01),and TMH increased significantly at 1 and 3mo(P<0.01,P<0.001,respectively).Conjunctival lissamine green staining improved only at 2mo(P<0.05),while corneal fluorescein staining showed no significant changes.Overall LLT remained unchanged,but the PBR<1 subgroup exhibited significant LLT elevation at 3mo(P<0.05),unlike the PBR=1 subgroup.Conjunctival mRNA expression of MUC1,MUC5AC,MUC16,and MUC20 was significantly upregulated at 1 and 3mo(all P<0.01),and MUC4 expression increased significantly only at 1mo(P<0.001).CONCLUSION:In patients with VDT-associated DED,3%diquafosol ophthalmic solution dramatically reduced symptoms and enhanced tear film stability by promoting ocular surface muco-aqueous secretion.Patients with better blinking habits(PBR<1)demonstrate greater LLT improvement than those with poorer habits.
