Nephroprevention strategies are crucial for handling chronic kidney disease(CKD) complications, and slowing its progression. However, these preventative measures should be guided by major geriatrics principles in orde...Nephroprevention strategies are crucial for handling chronic kidney disease(CKD) complications, and slowing its progression. However, these preventative measures should be guided by major geriatrics principles in order to help nephrologists to adequately handle the oldest old with CKD. These geriatric concepts consist of taking into account the relevance of choosing an individualized therapy, handling clinical frailty, and keeping a geriatric perspective which means that a good quality of life is sometimes a more important therapeutic objective inoctogenarians than merely prolonging life. Even though nephroprevention strategies for treating the oldest old with CKD are basically similar to those applied to younger patients such as low sodium and protein diet, optimized hemoglobin levels, blood pressure and metabolic control, the treating physician or care provider must at all times be ready to make fundamental adjustments and tweak patient care paradigms and objectives if and when the initial therapeutic options applied have caused unintended clinical consequences and complications. Additionally, the sarcopenia status should also be evaluated and treated in very old CKD patients.展开更多
Normal aging is associated with declines of perception and cognition. Inversely, emotions seem to be preserved compared to younger adults. Viewing, neutral, dramatic and comic films, emotions were evaluated in four ge...Normal aging is associated with declines of perception and cognition. Inversely, emotions seem to be preserved compared to younger adults. Viewing, neutral, dramatic and comic films, emotions were evaluated in four generations of woman from a 104-year old ancestress. At the very old age, from this case report, emotions were differently expressed while arousal was still preserved. A constant emotion of scare was expressed during the viewing of these three films (p 0.001) with significant higher level of disgust (p ≤ 0.01). Only perceptual deficiency cannot explain this difference as cognitive tasks revealed a mild cognitive impairment detected by the Mini Mental State Examination and a substantial impairment on the executive functions by using the Delayed response tasks. These results emphasize that some emotions in a normal aging centenarian are still present, even if not appropriates, and different in comparison to a young adult control group. From this study, it is expected that emotion analysis in old adults viewing selected short films will predict longevity and could discriminate normal processes occurring during normal aging from neurodegenerative diseases.展开更多
文摘Nephroprevention strategies are crucial for handling chronic kidney disease(CKD) complications, and slowing its progression. However, these preventative measures should be guided by major geriatrics principles in order to help nephrologists to adequately handle the oldest old with CKD. These geriatric concepts consist of taking into account the relevance of choosing an individualized therapy, handling clinical frailty, and keeping a geriatric perspective which means that a good quality of life is sometimes a more important therapeutic objective inoctogenarians than merely prolonging life. Even though nephroprevention strategies for treating the oldest old with CKD are basically similar to those applied to younger patients such as low sodium and protein diet, optimized hemoglobin levels, blood pressure and metabolic control, the treating physician or care provider must at all times be ready to make fundamental adjustments and tweak patient care paradigms and objectives if and when the initial therapeutic options applied have caused unintended clinical consequences and complications. Additionally, the sarcopenia status should also be evaluated and treated in very old CKD patients.
文摘Normal aging is associated with declines of perception and cognition. Inversely, emotions seem to be preserved compared to younger adults. Viewing, neutral, dramatic and comic films, emotions were evaluated in four generations of woman from a 104-year old ancestress. At the very old age, from this case report, emotions were differently expressed while arousal was still preserved. A constant emotion of scare was expressed during the viewing of these three films (p 0.001) with significant higher level of disgust (p ≤ 0.01). Only perceptual deficiency cannot explain this difference as cognitive tasks revealed a mild cognitive impairment detected by the Mini Mental State Examination and a substantial impairment on the executive functions by using the Delayed response tasks. These results emphasize that some emotions in a normal aging centenarian are still present, even if not appropriates, and different in comparison to a young adult control group. From this study, it is expected that emotion analysis in old adults viewing selected short films will predict longevity and could discriminate normal processes occurring during normal aging from neurodegenerative diseases.
