目的评估简明幸福与生活质量满意度问卷(the short form version of the quality of life enjoyment and satis-faction questionnaire,Q-LES-Q-SF)在焦虑障碍患者中的信度及效度。方法对山东省精神卫生中心和山东省安康医院163例焦虑...目的评估简明幸福与生活质量满意度问卷(the short form version of the quality of life enjoyment and satis-faction questionnaire,Q-LES-Q-SF)在焦虑障碍患者中的信度及效度。方法对山东省精神卫生中心和山东省安康医院163例焦虑障碍患者和按1∶1的比例选取与其相匹配的162名健康对照者进行Q-LES-Q-SF、世界卫生组织生活质量测定量表简表(the world health organization quality of life brief questionnaire,WHOQOL-BREF)和一般资料评定。结果 Q-LES-Q-SF各条目与总分的相关系数r为0.326～0.707(P<0.01);Q-LES-Q-SF的Cron-bach'sα系数为0.851,85例患者重测信度系数为0.911(P<0.01);Q-LES-Q-SF总分与WHOQOL-BREF各维度及总分呈显著相关(r=0.568～0.805,P<0.01),研究组与正常对照组Q-LES-Q-SF评分差异有统计学意义(如总分,t=13.071,P<0.01)。结论 Q-LES-Q-SF具有较好的信度及效度,可用于焦虑障碍患者的生活质量评价。展开更多
目的 将中文版简版言语空间听觉质量量表(C-SSQ12)在临床上用于老年性聋的听力评估,并将C-SSQ12得分与纯音听阈值进行比较,分析C-SSQ12得分与老年性听力损失的相关性。方法 选取2022年10月—2023年10月首都医科大学附属北京朝阳医院耳...目的 将中文版简版言语空间听觉质量量表(C-SSQ12)在临床上用于老年性聋的听力评估,并将C-SSQ12得分与纯音听阈值进行比较,分析C-SSQ12得分与老年性听力损失的相关性。方法 选取2022年10月—2023年10月首都医科大学附属北京朝阳医院耳鼻咽喉头颈外科门诊患者411例,其中老年性聋患者296例,根据纯音听阈测试言语频率均值(4f-PTA),分为轻度听力损失组(20≤4f-PTA<35 dB HL)141例、中度听力损失组(35≤4f-PTA<50 dB HL)78例。中重度听力损失组(50≤4f-PTA<65 dB HL)59例和重度及以上听力损失组(4f-PTA≥65dB HL)18例,正常听力组(4f-PTA<20 dB HL)115例,完成C-SSQ12填写和纯音听阈测试。采用Pearson相关性分析,观察老年性聋患者4f-PTA与C-SSQ12得分及其在言语感知维度、空间听觉维度以及听觉质量维度得分的相关性。利用单因素方差分析比较轻度、中度、中重度、重度及以上听力损失组C-SSQ12得分差异。绘制ROC曲线,计算曲线下面积(AUC)评估C-SSQ12对显著性听力损失的诊断效能。结果 C-SSQ12得分及其在言语感知维度、空间听觉维度以及听觉质量维度得分均与老年性聋患者4f-PTA呈显著负相关(P <0.01)。针对C-SSQ12绘制ROC曲线,AUC为0.884,敏感性为82.9%、特异性为79.2%、阳性预测值为62.5%、阴性预测值为93.1%,约登指数为0.62,截断值为6.56分。结论 C-SSQ12得分与纯音听阈值呈显著负相关,C-SSQ12具有良好的敏感性、特异性与诊断效能,可作为听力检查的有效补充,得分能够反映老年性聋患者在言语感知、空间听觉以及听觉质量维度下的听功能障碍,可用于老年性聋的筛查。展开更多
目的分析社交反应量表简版(social responsiveness scale short form,SRS-SF)的信效度,探讨其在中国孤独症儿童群体中的适用性。方法选取符合《精神障碍诊断与统计手册》第5版(Diagnostic and Statistical Manual of Mental Disorders,5...目的分析社交反应量表简版(social responsiveness scale short form,SRS-SF)的信效度,探讨其在中国孤独症儿童群体中的适用性。方法选取符合《精神障碍诊断与统计手册》第5版(Diagnostic and Statistical Manual of Mental Disorders,5th edition,DSM-5)诊断标准的孤独症谱系障碍(autism spectrum disorder,ASD)患儿140例,以及非孤独症谱系障碍(Non-ASD)儿童58例为研究对象。由父母或主要照养人根据孩子的情况填写SRS以及长处和困难问卷(strength and difficulty questionnaire,SDQ)家长版,并选取其中42例儿童的父母或主要照养人间隔3个月再次填写SRS,依据SRS-SF的条目内容对所得的数据进行信效度与受试者工作特征曲线(receiver operating characteristic curve,ROC)分析,以评估SRS-SF的适用性。结果①SRS-SF的内部一致性系数Cronbach'sα为0.879,重测系数为0.511;②SRS-SF各因子及总分与SRS之间呈高度正相关(r=0.853~0.960,P<0.001);③SRS-SF总分与SDQ中的困难总分以及亲社会行为呈中度相关(|r|=0.349~0.585,P<0.001);④ASD组的SRS-SF各因子及总分均高于Non-ASD组(t=-8.367^-2.841,P<0.01);⑤SRS-SF的ROC曲线下面积以及灵敏度高于SRS。结论SRS-SF在中国ASD儿童群体中具有良好的信效度,可作为一种有效的ASD早期筛查工具。展开更多
BACKGROUND Despite significant advancements in liver transplantation(LT)surgical procedures and perioperative care,post-LT biliary complications(BCs)remain a significant source of morbidity,mortality,and graft failure...BACKGROUND Despite significant advancements in liver transplantation(LT)surgical procedures and perioperative care,post-LT biliary complications(BCs)remain a significant source of morbidity,mortality,and graft failure.In addition,data are conflicting regarding the health-related quality of life(HRQoL)of LT recipients.Thus,the success of LT should be considered in terms of both the survival and recovery of HRQoL.AIM To assess the impact of BCs on the HRQoL of live-donor LT recipients(LDLT-Rs).METHODS We retrospectively analysed data for 25 LDLT-Rs who developed BCs post-LT between January 2011 and December 2016 at our institution.The Short Form 12 version 2(SF 12v2)health survey was used to assess their HRQoL.We also included 25 LDLT-Rs without any post-LT complications as a control group.RESULTS The scores for HRQoL of LDLT-Rs who developed BCs were significantly higher than the norm-based scores in the domains of physical functioning(P=0.003),role-physical(P<0.001),bodily pain(P=0.003),general health(P=0.004),social functioning(P=0.005),role-emotional(P<0.001),and mental health(P<0.001).No significant difference between the two groups regarding vitality was detected(P=1.000).The LDLT-Rs with BCs had significantly lower scores than LDLT-Rs without BCs in all HRQoL domains(P<0.001)and the mental(P<0.001)and physical(P=0.0002)component summary scores.CONCLUSION The development of BCs in LDLT-Rs causes a lower range of improvement in HRQoL.展开更多
文摘目的评估简明幸福与生活质量满意度问卷(the short form version of the quality of life enjoyment and satis-faction questionnaire,Q-LES-Q-SF)在焦虑障碍患者中的信度及效度。方法对山东省精神卫生中心和山东省安康医院163例焦虑障碍患者和按1∶1的比例选取与其相匹配的162名健康对照者进行Q-LES-Q-SF、世界卫生组织生活质量测定量表简表(the world health organization quality of life brief questionnaire,WHOQOL-BREF)和一般资料评定。结果 Q-LES-Q-SF各条目与总分的相关系数r为0.326～0.707(P<0.01);Q-LES-Q-SF的Cron-bach'sα系数为0.851,85例患者重测信度系数为0.911(P<0.01);Q-LES-Q-SF总分与WHOQOL-BREF各维度及总分呈显著相关(r=0.568～0.805,P<0.01),研究组与正常对照组Q-LES-Q-SF评分差异有统计学意义(如总分,t=13.071,P<0.01)。结论 Q-LES-Q-SF具有较好的信度及效度,可用于焦虑障碍患者的生活质量评价。
文摘目的 将中文版简版言语空间听觉质量量表(C-SSQ12)在临床上用于老年性聋的听力评估,并将C-SSQ12得分与纯音听阈值进行比较,分析C-SSQ12得分与老年性听力损失的相关性。方法 选取2022年10月—2023年10月首都医科大学附属北京朝阳医院耳鼻咽喉头颈外科门诊患者411例,其中老年性聋患者296例,根据纯音听阈测试言语频率均值(4f-PTA),分为轻度听力损失组(20≤4f-PTA<35 dB HL)141例、中度听力损失组(35≤4f-PTA<50 dB HL)78例。中重度听力损失组(50≤4f-PTA<65 dB HL)59例和重度及以上听力损失组(4f-PTA≥65dB HL)18例,正常听力组(4f-PTA<20 dB HL)115例,完成C-SSQ12填写和纯音听阈测试。采用Pearson相关性分析,观察老年性聋患者4f-PTA与C-SSQ12得分及其在言语感知维度、空间听觉维度以及听觉质量维度得分的相关性。利用单因素方差分析比较轻度、中度、中重度、重度及以上听力损失组C-SSQ12得分差异。绘制ROC曲线,计算曲线下面积(AUC)评估C-SSQ12对显著性听力损失的诊断效能。结果 C-SSQ12得分及其在言语感知维度、空间听觉维度以及听觉质量维度得分均与老年性聋患者4f-PTA呈显著负相关(P <0.01)。针对C-SSQ12绘制ROC曲线,AUC为0.884,敏感性为82.9%、特异性为79.2%、阳性预测值为62.5%、阴性预测值为93.1%,约登指数为0.62,截断值为6.56分。结论 C-SSQ12得分与纯音听阈值呈显著负相关,C-SSQ12具有良好的敏感性、特异性与诊断效能,可作为听力检查的有效补充,得分能够反映老年性聋患者在言语感知、空间听觉以及听觉质量维度下的听功能障碍,可用于老年性聋的筛查。
文摘目的分析社交反应量表简版(social responsiveness scale short form,SRS-SF)的信效度,探讨其在中国孤独症儿童群体中的适用性。方法选取符合《精神障碍诊断与统计手册》第5版(Diagnostic and Statistical Manual of Mental Disorders,5th edition,DSM-5)诊断标准的孤独症谱系障碍(autism spectrum disorder,ASD)患儿140例,以及非孤独症谱系障碍(Non-ASD)儿童58例为研究对象。由父母或主要照养人根据孩子的情况填写SRS以及长处和困难问卷(strength and difficulty questionnaire,SDQ)家长版,并选取其中42例儿童的父母或主要照养人间隔3个月再次填写SRS,依据SRS-SF的条目内容对所得的数据进行信效度与受试者工作特征曲线(receiver operating characteristic curve,ROC)分析,以评估SRS-SF的适用性。结果①SRS-SF的内部一致性系数Cronbach'sα为0.879,重测系数为0.511;②SRS-SF各因子及总分与SRS之间呈高度正相关(r=0.853~0.960,P<0.001);③SRS-SF总分与SDQ中的困难总分以及亲社会行为呈中度相关(|r|=0.349~0.585,P<0.001);④ASD组的SRS-SF各因子及总分均高于Non-ASD组(t=-8.367^-2.841,P<0.01);⑤SRS-SF的ROC曲线下面积以及灵敏度高于SRS。结论SRS-SF在中国ASD儿童群体中具有良好的信效度,可作为一种有效的ASD早期筛查工具。
文摘BACKGROUND Despite significant advancements in liver transplantation(LT)surgical procedures and perioperative care,post-LT biliary complications(BCs)remain a significant source of morbidity,mortality,and graft failure.In addition,data are conflicting regarding the health-related quality of life(HRQoL)of LT recipients.Thus,the success of LT should be considered in terms of both the survival and recovery of HRQoL.AIM To assess the impact of BCs on the HRQoL of live-donor LT recipients(LDLT-Rs).METHODS We retrospectively analysed data for 25 LDLT-Rs who developed BCs post-LT between January 2011 and December 2016 at our institution.The Short Form 12 version 2(SF 12v2)health survey was used to assess their HRQoL.We also included 25 LDLT-Rs without any post-LT complications as a control group.RESULTS The scores for HRQoL of LDLT-Rs who developed BCs were significantly higher than the norm-based scores in the domains of physical functioning(P=0.003),role-physical(P<0.001),bodily pain(P=0.003),general health(P=0.004),social functioning(P=0.005),role-emotional(P<0.001),and mental health(P<0.001).No significant difference between the two groups regarding vitality was detected(P=1.000).The LDLT-Rs with BCs had significantly lower scores than LDLT-Rs without BCs in all HRQoL domains(P<0.001)and the mental(P<0.001)and physical(P=0.0002)component summary scores.CONCLUSION The development of BCs in LDLT-Rs causes a lower range of improvement in HRQoL.
