Dengue is one of the most common arthropod-borne viral diseases in humans and it is a leading cause of illness and death in the tropical and subtropical regions of the world. It is thought to account for 400 million c...Dengue is one of the most common arthropod-borne viral diseases in humans and it is a leading cause of illness and death in the tropical and subtropical regions of the world. It is thought to account for 400 million cases annually among approximately 3.97 billion people at risk of infection in 128 endemic countries. Despite the global prevalence of the disease, the availability of a vaccine is limited in most countries in the endemic areas. Most endemic countries in South America, South East Asia and Africa serve as attractive touristic sites for people from non-endemic countries who become infected and export the virus to dengue-free regions. Dengue fever typically resembles malaria and in endemic countries most cases of dengue are treated as presumptive malaria. Consequently, routine dengue diagnosis among persons with fever will offer early treatment and reduce the burden of the disease. Also, routine testing among travellers from endemic countries will reduce importation and prevent the geographical expansion of dengue. In this essay, we seek to highlight the usefulness of routine dengue testing in endemic countries.展开更多
This paper considers an epidemic model of a vector-borne disease which has the vectormediated transmission only. The incidence term is of the bilinear mass-action form. It is shown that the global dynamics is complete...This paper considers an epidemic model of a vector-borne disease which has the vectormediated transmission only. The incidence term is of the bilinear mass-action form. It is shown that the global dynamics is completely determined by the basic reproduction number Ro. If Ro ≤ 1, the diseasefree equilibrium is globally stable and the disease dies out. If Ro 〉 1, a unique endemic equilibrium is globally stable in the interior of the feasible region and the disease persists at the endemic equilibrium. Numerical simulations are presented to illustrate the results.展开更多
文摘Dengue is one of the most common arthropod-borne viral diseases in humans and it is a leading cause of illness and death in the tropical and subtropical regions of the world. It is thought to account for 400 million cases annually among approximately 3.97 billion people at risk of infection in 128 endemic countries. Despite the global prevalence of the disease, the availability of a vaccine is limited in most countries in the endemic areas. Most endemic countries in South America, South East Asia and Africa serve as attractive touristic sites for people from non-endemic countries who become infected and export the virus to dengue-free regions. Dengue fever typically resembles malaria and in endemic countries most cases of dengue are treated as presumptive malaria. Consequently, routine dengue diagnosis among persons with fever will offer early treatment and reduce the burden of the disease. Also, routine testing among travellers from endemic countries will reduce importation and prevent the geographical expansion of dengue. In this essay, we seek to highlight the usefulness of routine dengue testing in endemic countries.
基金supported by the Natural Science Foundation of China under Grant Nos.10371105 and 10671166the Natural Science Foundation of Henan Province under Grant No.0312002000
文摘This paper considers an epidemic model of a vector-borne disease which has the vectormediated transmission only. The incidence term is of the bilinear mass-action form. It is shown that the global dynamics is completely determined by the basic reproduction number Ro. If Ro ≤ 1, the diseasefree equilibrium is globally stable and the disease dies out. If Ro 〉 1, a unique endemic equilibrium is globally stable in the interior of the feasible region and the disease persists at the endemic equilibrium. Numerical simulations are presented to illustrate the results.
