In their recent paper Pereira et al.(2025)claim that validation is overlooked in mapping and modelling of ecosystem services(ES).They state that“many studies lack critical evaluation of the results and no validation ...In their recent paper Pereira et al.(2025)claim that validation is overlooked in mapping and modelling of ecosystem services(ES).They state that“many studies lack critical evaluation of the results and no validation is provided”and that“the validation step is largely overlooked”.This assertion may have been true several years ago,for example,when Ochoa and Urbina-Cardona(2017)made a similar observation.However,there has been much work on ES model validation over the last decade.展开更多
Background:Investigators from low-,middle-,and high-income countries representing 6 continents contributed to the development of the Global Adolescent and Child Physical Activity Questionnaire(GAC-PAQ).The GAC-PAQ is ...Background:Investigators from low-,middle-,and high-income countries representing 6 continents contributed to the development of the Global Adolescent and Child Physical Activity Questionnaire(GAC-PAQ).The GAC-PAQ is designed to assess physical activity(PA)across all key domains(i.e.,school,chores,work/volunteering,transport,free time,outdoor time).It aimed to address multiple gaps in global PA surveillance(e.g.,omission of important PA domains,insufficient cultural adaptation,underrepresentation of rural areas in questionnaire validation studies).The purpose of this study was to assess the content validity of the GAC-PAQ among PA experts,8-to 17-year-olds,and one of their parents/guardians,and to discuss changes made to the questionnaire based on participants'feedback.Methods:Sixty-two experts in PA measurement and/or surveillance from 24 countries completed an online survey that included both closed-and open-ended questions about the content validity of the GAC-PAQ.The proportion of experts who agreed or strongly agreed with the items was calculated.Child-parent/guardian dyads from 15 countries(n=250;10-40 per country)participated in a structured cognitive interview to assess the clarity of the questions and response options,and they were encouraged to provide suggestions to improve clarity and facilitate completion of the questionnaire.Participating countries are:Aotearoa New Zealand,Brazil,Canada,China,Colombia,Czech Republic,India,Malawi,Mexico,Nepal,Nigeria,Spain,Sweden,Thailand,and the United Arab Emirates.Interviews were conducted in 13 different languages and structured by PA domain.Generic images were included to help participants in answering questions about PA intensity.Results:Expert agreement with the items for each domain exceeded 75%,and their qualitative feedback was used to revise the questionnaire before cognitive interviews.In general,participants found the questionnaire to be comprehensive.Adolescents(12-17 years)found it easier than children(8-11 years)to answer the questions.Several children struggled to answer questions about the duration and intensity of activities and/or concepts related to travel modes,active trips,and organized activities.Many parents/guardians were unsure about the frequency,duration,and intensity of their children's or adolescents'PA at school and/or recommended using more culturally relevant and appropriate images.Some participants misunderstood the concept of activities that“make you stronger”(intended to assess resistance activities)and/or struggled to differentiate between work,volunteering,and chores.Conclusion:Participants'feedback was used to develop a revised,simplified,and culturally adapted GAC-PAQ,which will be pilot-tested in all15 countries in an App that will include country-specific images and narration in local languages.Further research is needed to assess the reliability and validity of the revised GAC-PAQ.展开更多
This study examines the reliability and validity of AI-generated scoring for continuation writing tasks.By comparing GPT-4 with eight experienced human raters across 21 student responses,it evaluates AI’s consistency...This study examines the reliability and validity of AI-generated scoring for continuation writing tasks.By comparing GPT-4 with eight experienced human raters across 21 student responses,it evaluates AI’s consistency,severity,and alignment with human scoring criteria.Results show that AI exhibits high self-consistency and adapts effectively to different scoring roles(e.g.,teacher vs.highstakes rater).However,AI scores were more lenient than human raters and demonstrated divergent evaluation focuses—prioritizing narrative coherence and emotional depth,while teachers emphasized linguistic accuracy and richness of detail.The findings suggest AI’s potential as a supplementary assessment tool,offering rapid,holistic feedback,but highlight the need for further calibration to align with educational standards.Implications include exploring hybrid evaluation models that leverage the strengths of both AI and human raters to achieve more equitable,efficient,and pedagogically meaningful writing assessments.展开更多
Background:The World Health Organization Disability Assessment Schedule 2.0(WHODAS 2.0)is a popular tool for eval-uating functioning and disability in a range of population demographics and medical situations.However,...Background:The World Health Organization Disability Assessment Schedule 2.0(WHODAS 2.0)is a popular tool for eval-uating functioning and disability in a range of population demographics and medical situations.However,very little is known about the WHODAS 2.0's validity and reliability,particularly when dealing with potentially life-threatening maternal condi-tions(PLTCs).The aim of this study was to evaluate the validity of the WHODAS 2.0 Tigrigna version.Methods:This cross-sectional study was conducted in Tigray,northern Ethiopia,from December 15 to 20,2023.Following translation and back translation,women who had experienced PLTCs during a recent pregnancy,childbirth,or postpartum period were administered the 36-item WHODAS 2.0 in Tigrigna version 6 months after the childbirth.In total,121 women with a history of PLTCs participated.Cronbach′sαwas used to evaluate internal consistency in all six WHODAS 2.0 domains,while Spearman′s correlation coefficient was used to evaluate convergent validity.With confirmatory factor analysis,construct validity was also examined.Results:All domain scores of the Tigrigna version of the WHODAS 2.0 indicated excellent internal consistency(α=0.917-0.978 for 36 items andα=0.874-0.940 for 12 items),while the Cronbach′sαcoefficients for the summary score were 0.981 and 0.952 for 36 and 12 items,respectively.The convergent validity between the 36-item and 12-item WHODAS 2.0 showed a strong correlation between similar constructs(r=0.909-0.981).Conclusion:Despite the small sample limitation,the WHODAS 2.0 tool adapted to the Tigrigna version indicated an acceptable reliability and validity and therefore could be applied to women with a history of PLTCs at 6 months postpartum.展开更多
It remains difficult to automate the creation and validation of Unified Modeling Language(UML)dia-grams due to unstructured requirements,limited automated pipelines,and the lack of reliable evaluation methods.This stu...It remains difficult to automate the creation and validation of Unified Modeling Language(UML)dia-grams due to unstructured requirements,limited automated pipelines,and the lack of reliable evaluation methods.This study introduces a cohesive architecture that amalgamates requirement development,UML synthesis,and multimodal validation.First,LLaMA-3.2-1B-Instruct was utilized to generate user-focused requirements.Then,DeepSeek-R1-Distill-Qwen-32B applies its reasoning skills to transform these requirements into PlantUML code.Using this dual-LLM pipeline,we constructed a synthetic dataset of 11,997 UML diagrams spanning six major diagram families.Rendering analysis showed that 89.5%of the generated diagrams compile correctly,while invalid cases were detected automatically.To assess quality,we employed a multimodal scoring method that combines Qwen2.5-VL-3B,LLaMA-3.2-11B-Vision-Instruct and Aya-Vision-8B,with weights based on MMMU performance.A study with 94 experts revealed strong alignment between automatic and manual evaluations,yielding a Pearson correlation of r=0.82 and a Fleiss’Kappa of 0.78.This indicates a high degree of concordance between automated metrics and human judgment.Overall,the results demonstrated that our scoring system is effective and that the proposed generation pipeline produces UML diagrams that are both syntactically correct and semantically coherent.More broadly,the system provides a scalable and reproducible foundation for future work in AI-driven software modeling and multimodal verification.展开更多
Background:Antipsychotic-induced movement disorders(AIMDs)are prevalent side effects of antipsychotics,particularly during the acute phase of treatment.This study aimed to elucidate the genetic mechanisms underlying A...Background:Antipsychotic-induced movement disorders(AIMDs)are prevalent side effects of antipsychotics,particularly during the acute phase of treatment.This study aimed to elucidate the genetic mechanisms underlying AIMDs using a genome-wide association study(GWAS).Methods:GWASs on AIMDs were conducted in three independent cohorts:a discovery cohort of 3067 patients(2016 subjects were reserved after quality control),a validation cohort of 277 patients,and a multi-ancestry validation cohort of 766 patients.Subsequent post-GWAS analyses included gene-based analyses,transcriptome-wide association studies(TWASs),and polygenic risk score(PRS)profiling.Results:Our study identified two loci located in RAB44 gene(rs116249243,P=5.98×10^(-9);rs117097482,P=1.17×10^(-8))associated with extrapyramidal symptoms(EPSs),1 locus(rs6826172,P=5.56×10^(-9))related to akathisia,and 76 loci linked to involuntary movements(11 genes were mapped).Risk loci located in CNTNAP2,LUZP2,TMEM167A,and RAB44 genes were successfully replicated in the validation cohort,whereas the locus located in RAB44 was also replicated in the multi-ancestry cohort.Gene-based analyses indicated that XRCC4 and PAIP2B reached significance at the genome-wide level in involuntary movements.Tissue expression analysis revealed that involuntary movement-related genes are predominantly expressed in the substantia nigra.Additionally,the TWAS suggested a causal relationship between XRCC4 and involuntary movement.The PRSs derived from the discovery cohort significantly predicted AIMDs in the validation cohort,with area under the receiver operating characteristic curve(AUC)values from 0.60 to 0.80.Conclusions:Our findings highlight the role of substantia nigra related gene polymorphisms in AIMDs.This study provides novel insights into the pathogenesis of AIMDs and supports the potential for personalized treatment approaches for schizophrenia.展开更多
Background The patient-reported Dimensional Anhedonia Rating Scale(DARS)has been adapted into Chinese,so there is a need to evaluate its measurement properties in a Chinese population.Aims To evaluate the reliability ...Background The patient-reported Dimensional Anhedonia Rating Scale(DARS)has been adapted into Chinese,so there is a need to evaluate its measurement properties in a Chinese population.Aims To evaluate the reliability and validity of the DARS among Chinese individuals with major depressive disorder(MDD)and its treatment sensitivity in a prospective clinical study.Methods Data were from a multicentre,prospective clinical study(NCT03294525),which recruited both patients with MDD,who were followed for 8 weeks,and healthy controls(HCs),assessed at baseline only.The analysis included confirmatory factor analysis,validity and sensitivity to change.Results Patients’mean(standard deviation(SD))age was 34.8(11.0)years,with 68.7%being female.75.2%of patients with MDD had melancholic features,followed by 63.8%with anxious distress.Patients had experienced MDD for a mean(SD)of 9.2(18)months.DARS scores covered the full range of severity with no major floor or ceiling effects.Confirmatory factor analysis showed adequate fit statistics(comparative fit index 0.976,goodness-of-fit index 0.935 and root mean square error of approximation 0.055).Convergent validity with anhedonia-related measures was confirmed.While the correlation between the DARS and the Hamilton Depression Rating Scale was not strong(r=0.31,baseline),the DARS was found to differentiate between levels of depression.Greater improvements in DARS scores were seen with the Hamilton Rating Scale for Depression responder group(effect size 1.16)compared with the non-responder group(effect size 0.46).Conclusions This study comprehensively evaluated the measurement properties of the DARS using a Chinese population with MDD.Overall,the Chinese version of DARS demonstrates good psychometric properties and has been found to be responsive to change during antidepressant treatment.The DARS is a suitable scale for assessing patient-reported anhedonia in future clinical trials.展开更多
The process of selecting an artificial intelligence(AI)model to assist clinical diagnosis of a particular pathology and its validation tests is relevant since the values of accuracy,sensitivity and specificity may not...The process of selecting an artificial intelligence(AI)model to assist clinical diagnosis of a particular pathology and its validation tests is relevant since the values of accuracy,sensitivity and specificity may not reflect the behavior of the method in a real environment.Here,we provide helpful considerations to increase the success of using an AI model in clinical practice.展开更多
The ongoing revolution in information technology is reshaping human life. In the realm of health behavior, wearable technology emerges as a leading digital solution,capturing physical behaviors (i.e., physical activit...The ongoing revolution in information technology is reshaping human life. In the realm of health behavior, wearable technology emerges as a leading digital solution,capturing physical behaviors (i.e., physical activity, sedentary habits, sleep patterns) within the 24-h cycle of daily life. Wearables are applied in research, clinical practice, and as lifestyle devices;most obvious, they promise to be a key element for increasing human physical activity, one of the biggest health challenges nowadays.展开更多
A self-centering bridge bent equipped with energy-dissipation(ED)beams is proposed.Quasi-static tests are conducted on self-centering bridge bents,both with and without ED beams,to validate the accuracy of the corresp...A self-centering bridge bent equipped with energy-dissipation(ED)beams is proposed.Quasi-static tests are conducted on self-centering bridge bents,both with and without ED beams,to validate the accuracy of the corresponding numerical models.The effects of various param-eters,such as the web area of ED beams,prestressing force of tendons,tendon arrangements,and number of column segments,on the seismic performance of self-centering bridge bents with ED beams are evaluated using the validated numerical model.The results demonstrate that the nu-merical models accurately replicate the quasi-static test results,with average errors in the lateral force remaining below 9.6%.The web area of ED beams significantly affects the strength,cumulative energy dissipation,and relative self-centering index(RSI)of the self-centering bridge bents.Increasing the prestressing force enhances the lateral force and self-centering capability of the bridge bents but has minimal effect on their ED capacity.Reducing the num-ber of segments in each column enhances the lateral force and cumulative hysteretic energy dissipation of the self-centering bridge bents while exerting an insignificant effect on the RSI.Thus,the proposed novel system is highly suitable for doubleor multicolumn piers supporting bridges in regions prone to strong earthquakes.展开更多
OBJECTIVE:To explore the potential molecular mechanism of Qigu capsule(芪骨胶囊,QGC) in the treatment of sarcopenia through network pharmacology and to verify it experimentally.METHODS:The active compounds of QGC and ...OBJECTIVE:To explore the potential molecular mechanism of Qigu capsule(芪骨胶囊,QGC) in the treatment of sarcopenia through network pharmacology and to verify it experimentally.METHODS:The active compounds of QGC and common targets between QGC and sarcopenia were screened from databases.Then the herbs-compounds-targets network,and protein-protein interaction(PPI) network was constructed.Gene ontology(GO) and Kyoto Encyclopedia of Genes and Genomes(KEGG) pathway enrichment analysis were performed by R software.Next,we used a dexamethasone-induced sarcopenia mouse model to evaluate the anti-sarcopenic mechanism of QGC.RESULTS:A total of 57 common targets of QGC and sarcopenia were obtained.Based on the enrichment analysis of GO and KEGG,we took the phosphatidylinositol 3-kinase(PI3K)/protein kinase B(Akt) signaling pathway as a key target to explore the mechanism of QGC on sarcopenia.Animal experiments showed that QGC could increase muscle strength and inhibit muscle fiber atrophy.In the model group,the expression of muscle ring finger-1 and Atrogin-1 were increased,while myosin heavy chain was decreased,QGC treatment reversed these changes.Moreover,compared with the model group,the expressions of pPI3K,p-Akt,p-mammalian target of rapamycin and pForkhead box O3 in the QGC group were all upregulated.CONCLUSION:QGC exerts an anti-sarcopenic effect by activating PI3K/Akt signaling pathway to regulate skeletal muscle protein metabolism.展开更多
Objective:Pelvic floor dysfunction is common among pregnant and postpartum women and significantly impacts quality of life.This study aims to translate the German Pelvic Floor Questionnaire for Pregnant and Postpartum...Objective:Pelvic floor dysfunction is common among pregnant and postpartum women and significantly impacts quality of life.This study aims to translate the German Pelvic Floor Questionnaire for Pregnant and Postpartum Women into Chinese and to evaluate its reliability and validity in the Chinese population.Methods:The questionnaire was translated using the Brislin model.A cross-sectional study was conducted among pregnant and postpartum women to assess the content validity,construct validity,Cronbach’sαcoefficient,test-retest reliability,and split-half reliability of the Chinese version.Results:A total of 72 women were included,with 6.9% being pregnant and 93.1% postpartum;the age was(32.3±3.6)years.The Chinese version of the questionnaire contains 4 dimensions and 45 items.The content validity index of individual items ranged from 0.833 to 1.000,with a scale-level content validity index of 0.977 and intraclass correlation coefficients(ICCs)exceeding 0.90.The overall Cronbach’s α coefficient was 0.891,with subscale coefficients ranging from 0.732 to 0.884(all ICCs>0.70).The testretest reliability of the total scale was 0.833,and for the 4 dimensions,bladder,bowel,prolapse,and sexual function,the values were 0.776,0.579,0.732,and 0.645,respectively.The split-half reliability was 0.74.Conclusion:The Chinese version of the questionnaire demonstrated good reliability and validity,indicating its applicability in assessing pelvic floor dysfunction and associated risk factors during pregnancy and postpartum.展开更多
The purpose of this paper is to look into how reliable and valid the Persian version of the Cannabis Use Disorder Identification Test-Revised (CUDIT-R-Pr) is. It will also compare the screening features of the CUDIT-R...The purpose of this paper is to look into how reliable and valid the Persian version of the Cannabis Use Disorder Identification Test-Revised (CUDIT-R-Pr) is. It will also compare the screening features of the CUDIT-R with those of the DSM-5 criteria for cannabis use disorder (CUD) based on the SCID-5-CT in a group of university students in Tehran, Iran. The study used the stratified random sampling technique to collect data from 541 students (19 to 24 years old) who used cannabis in Tehran universities in 2024. Confirmatory factor analysis confirmed the uni-dimensionality of the CUDIT-R-Pr. We checked the reliability of the CUDIT-R-Pr using Cronbach Alpha, split-half, inter-rater, test-retest stability over time, and parallel testing equivalence. The results indicated that CUDIT-R-Pr is reliable, reproducible, and responsive, with substantial agreement and adequate interpretability. The CUDIT-R shows that it can tell the difference between different levels of cannabis use severity, which is known as discriminant validity. Receiver operating characteristic analyses confirmed this, using an area under the receiver operating characteristics curve (AUC = 0.95) at a cutoff of ten or less. This allowed CUDIT-R-Pr to accurately predict any DSM-5 based on the highest correctly classified value (0.89), demonstrating high levels of sensitivity (0.96), specificity (0.69), and Youden value (0.65). The exact maximum Youden index (0.72) showed that CUDIT-R-Pr could also predict moderate DSM-5 with a cutoff of twelve or less. To validate and generalize the CUDIT-R-Pr for use among Iranian cannabis users, we need more research.展开更多
Objectives This study aimed to validate the Russian version of the Copenhagen Burnout Inventory(R-CBI)among nurses in Kazakhstan and Kyrgyzstan and explored factors contributing to burnout.Methods The original Copenha...Objectives This study aimed to validate the Russian version of the Copenhagen Burnout Inventory(R-CBI)among nurses in Kazakhstan and Kyrgyzstan and explored factors contributing to burnout.Methods The original Copenhagen Burnout Inventory(CBI)was translated into the R-CBI using a rigorous forward-backward method and reviewed by experts.Between July and November 2022,1,530 nurses were recruited through convenience sampling method from various nursing settings in Kazakhstan and Kyrgyzstan to test the scale’s reliability and validity,including confirmatory factor analysis(CFA),internal consistency reliability,and concurrent validity.A linear regression analysis was conducted to identify influencing factors of burnout.Results The content of the R-CBI is consistent with the original CBI,consisting of 19 items with three dimensions.The Cronbach’sαcoefficient is 0.926 in Kazakhstan and 0.922 in Kyrgyzstan,ranging from 0.830 to 0.898 for three dimensions.The CFA results among nurses in Kazakhstan and Kyrgyzstan supported the three-factor structure of R-CBI with good fit indices.Concurrent validity was established through significant correlations(P<0.001)with job satisfaction questionnaire(r=−0.457),Depression Anxiety Stress Scales(r=0.506 in depression,r=0.485 in anxiety,r=0.564 in stress),and WHO-5 Well-Being Index(r=−0.528).The overall burnout level was 36.1±17.6 and 37.5±17.4 in Kazakhstani and Kyrgyzstani nurses,respectively.Significant influencing factors of burnout included gender,age,educational level,and COVID-19 infection history.Conclusions The R-CBI was proved to be a reliable and valid tool for assessing nurses’burnout in Kazakhstan and Kyrgyzstan.展开更多
BACKGROUND During the gradual decline of physical and social functioning associated with end-stage renal disease,patients might experience a premonition of impending death,resulting in a series of pre-mourning grief r...BACKGROUND During the gradual decline of physical and social functioning associated with end-stage renal disease,patients might experience a premonition of impending death,resulting in a series of pre-mourning grief responses called preparatory grief.The preparatory grief in advanced cancer patients(PGAC)scale is the most widely used preparatory grief scale for patients on hemodialysis in China.AIM To verify the reliability and validity of the PGAC scale in patients on hemodialysis.METHODS In total,327 patients undergoing regular hemodialysis in the blood purification center of three grade-A tertiary hospitals in Guangdong and Guizhou provinces were selected by convenience sampling.The assessment was administered using the general information questionnaire and the Chinese version of PGAC.SPSS 25.0 and Amos 24.0 were used for item analysis,confirmatory factor analysis(CFA),convergent validity,and internal consistency reliability estimation.RESULTS In the modified Chinese version of PGAC,7 dimensions covering 27 total items were retained.CFA revealed a good fit of the factor model(chi-square degree of freedom=2.056,standardized root mean square residual=0.0479,root mean square error of approximation=0.0570,GFI=0.872,AGFI=0.841,IFI=0.931,CFI=0.930,TLI=0.919).The factor loadings of the items ranged 0.503-0.884.The composite reliability ranged 0.664-0.914,and the average variance extracted ranged 0.366-0.747.Cronbach’sαof the scale was 0.945,and Cronbach’sαfor various dimensions ranged 0.662-0.914.CONCLUSION The modified PGAC has good reliability and validity,and it can effectively measure preparatory grief in patients on hemodialysis.展开更多
Ecosystem services(ES)mapping and models have advanced in recent years.Improvements were made,and the assessments have transitioned from qualitative to quantitative.Although this is an important advancement,the ES map...Ecosystem services(ES)mapping and models have advanced in recent years.Improvements were made,and the assessments have transitioned from qualitative to quantitative.Although this is an important advancement,the ES mapping and modelling validation step has been overlooked,and this raises an important question in the credibility of the outcomes.This has been an important and unsolved issue in the ES research community that needs to be tackled.This highlight paper discusses the importance of validating single ES mapping and models.Conducting this using field or proximal/remote sensing raw data and not data from other models or stakeholder evaluation is important.A validation step should be mandatory in ES frameworks since it can assess the models’veracity,contribute to identifying the model’s weaknesses/strengths and ultimately represent a scientific advance in the field.This is easier to apply to the biophysical mapping and models of regulating and provisioning ES than to cultural ES,as the latter rely more on perception and cultural contexts.Also,ES supply models are easier to validate than demand and flow models.Robust and well-grounded models are essential for ensuring the reliability of individual ES maps and models and should be integrated into decision-making processes.Although several challenges arise related to the costs of data collection,in several cases prohibitive,and the time and the expertise needed to conduct this sampling and analysis,this is likely an imperative step that needs to be considered in the future.This will be beneficial in establishing ES research and improving decision-making and wellbeing.展开更多
BACKGROUND The Victorian institute of sports assessment for patellar tendons questionnaire(VISA-P),a valid tool for patellar tendinopathy,has been used for patellofemoral pain(PFP).AIM To validate VISA-P in PFP.METHOD...BACKGROUND The Victorian institute of sports assessment for patellar tendons questionnaire(VISA-P),a valid tool for patellar tendinopathy,has been used for patellofemoral pain(PFP).AIM To validate VISA-P in PFP.METHODS Study of validity,responsiveness and feasibility following COSMIN.Inclusion criteria:Subjects with PFP,aged 18 to 55.Agreement among 10 experts on the relevance and clarity of each item using Aiken's V coefficient determined content validity.An exploratory factorial analysis established structural validity.The correlation of VISA-P with knee injury and osteoarthritis outcome score for PFP and Osteoarthritis(KOOS-PF)and Kujala patellofemoral score(KPS;specific for PFP)analyzed the construct validity.Internal consistency was calculated with Cronbach'sαand test-retest reliability with the intraclass correlation coefficient(ICC).Feasibility considered the subjects'self-completion time.RESULTS The sample consisted of 103 knees from 73 subjects(47 female/26 male;aged 34.9±13 SD).The items were relevant and clear,with the exception of item-8,which didn't reach an acceptable level of agreement on clarity.Exploratory factorial analysis found a 2-factor solution,which explained 63.48%of the variance.VISAP achieved a strong and significant correlation with KOOS-PF(Spearman rho=0.826;P<0.001)and KPS(Spearman rho=0.771;P<0.001).The questionnaire showed adequate reliability(Cronbach'sα:0.752;ICC:0.934;P<0.0001;95%CI:0.902-0.955).The mean self-completion time was 232±0.52 SD seconds.CONCLUSION VISA-P proved to be valid and reliable to functionally assess PFP and/or chondromalacia patella.VISA-P is a feasible tool in the clinical and research environment,quick and easy to complete.展开更多
Chlorophyll a(Chl a)is a key photosynthetic pigment and an essential indicator of phytoplankton biomass.Accurate Chl a measurements are crucial for understanding marine biogeochemical processes.China launched the Chin...Chlorophyll a(Chl a)is a key photosynthetic pigment and an essential indicator of phytoplankton biomass.Accurate Chl a measurements are crucial for understanding marine biogeochemical processes.China launched the Chinese Ocean Color and Temperature Scanner(COCTS)aboard the HY-1D satellite in 2020,yet its Chl a products require further validation in complex coastal waters.This study assesses HY-1D Chl a products in the Bohai and Yellow Seas,two optically complex coastal regions,using in situ data collected during multiple cruises.Additionally,we compare HY-1D Chl a products with those from the Moderate Resolution Imaging Spectroradiometer(MODIS)and the Visible Infrared Imaging Radiometer Suite(VIIRS).We observed that although Chl a products from HY-1D are generally consistent with those from the MODIS and VIIRS in spatial distribution,there are still significant errors when compared with in situ data.Therefore,we developed a new blended algorithm to improve the accuracy of HY-1D Chl a products.The algorithm distinguishes between turbid and relatively clean waters using a classification index based on the ratio of remote sensing reflectance(R_(rs)(λ)).After the initial classification,we developed targeted algorithms based on the optical properties of different water bodies.The new model shows a significant improvement,reducing the mean absolute percentage error(MAPE)from 43.1%to 24.3%.Additionally,merging Chl a data from HY-1D,MODIS,and VIIRS maintains good accuracy,with HY-1D Chl a products significantly enhancing data coverage and robustness.This research provides important support for producing high-quality HY-1D Chl a products for coastal waters.展开更多
Objective:This study aims to develop an assessment tool for postoperative wound healing in adult patients with benign anal canal and rectal diseases and to validate its reliability and validity.Methods:Based on Levine...Objective:This study aims to develop an assessment tool for postoperative wound healing in adult patients with benign anal canal and rectal diseases and to validate its reliability and validity.Methods:Based on Levine’s Conservation Model as the theoretical framework,an item pool was formed through literature review,and the initial draft of the scale was refined through two rounds of Delphi expert consultation.A total of 200 postoperative patients were selected for item analysis,internal consistency testing,content validity,and structural validity analysis.Results:The final tool comprises four dimensions:energy conservation,structural integrity,personal integrity,and social integrity,with a total of 24 items.It demonstrates good content validity(I-CVI 0.82-1.00,S-CVI/Ave 0.95,S-CVI/UA 0.87)and excellent internal consistency(Cronbach’sαfor the overall scale was 0.934).Exploratory factor analysis revealed a KMO value of 0.931,Bartlett’s test of sphericityχ^(2)=4147.853(p<0.001),and four common factors were extracted,accounting for a cumulative variance contribution rate of 64.345%,indicating ideal structural validity.Conclusion:The results indicate that the assessment tool has good reliability and validity and can systematically evaluate postoperative wound healing,providing a scientific basis for clinical individualized nursing interventions.展开更多
Objective:This study aimed to translate the de Morton Mobility Index(DEMMI)into Thai and assess its measurement properties.Methods:The de Morton Mobility Index(DEMMI)was translated into Thai using a cross-cultural tra...Objective:This study aimed to translate the de Morton Mobility Index(DEMMI)into Thai and assess its measurement properties.Methods:The de Morton Mobility Index(DEMMI)was translated into Thai using a cross-cultural translation method.A cross-sectional study was conducted in four public hospitals in Thailand between January and March 2023.A total of 260 patients were recruited from outpatient clinics.Convergent and known-group validity were evaluated through hypothesis testing.Construct validity was examined using confirmatory factor analysis.Reliability was assessed using Cronbach’s a coefficient.We also employed the Rasch analysis to validate validity and person reliability.Results:Content validity was high(S-CVI=0.96,I-CVI range:0.80e1.00).Strong convergent validity was observed,with a significant correlation(r=0.761,P<0.001)between the Thai DEMMI and the Parker Mobility Scale(PMS).Known-group validity was evident,demonstrating differences in scores across various patient groups.A confirmatory factor analysis supported the hypothesized factor structure of the Thai DEMMI with good fit indices:χ^(2)(df=4)=5.101,P=0.2771;χ^(2)/df=1.275,RMSEA=0.033;CFI=0.998;TLI=0.995;SRMR=0.016.The Thai DEMMI exhibited high internal consistency(Cronbach’s a=0.88).Rasch analysis revealed good person reliability(0.91)and acceptable information-weighted fit means square statistic(0.73-1.06).However,most items showed good fit based on the outlier-sensitive fit means square statistics(Outfit MNSQ),one exhibited a high Outfit MNSQ value of 29.94,suggesting a potential misfit.Conclusion:This study demonstrated the acceptable validity and reliability of the Thai DEMMI.Further evaluation of its responsiveness to change is still recommended.展开更多
文摘In their recent paper Pereira et al.(2025)claim that validation is overlooked in mapping and modelling of ecosystem services(ES).They state that“many studies lack critical evaluation of the results and no validation is provided”and that“the validation step is largely overlooked”.This assertion may have been true several years ago,for example,when Ochoa and Urbina-Cardona(2017)made a similar observation.However,there has been much work on ES model validation over the last decade.
基金supported by a Project Grant(Grant No.PJT183705)an Early Career Investigator Prize(Grant No.ECP 184184)from the Canadian Institutes of Health Research+7 种基金a Prentice Institute Research Affiliate Fund Grant from the Prentice Institute for Global Population and Economy(Grant No.G00004116)a Te Herenga Waka Victoria University of Wellington Division of Science Health Engineering Architecture and Design Innovation Faculty Strategic Research Grant(Grant No.FSRG-SHEADI-10724)The Thailand Physical Activity Knowledge Development Centre(TPAK)/Thai Health Promotion Foundation provided funding for the cognitive interviews and pilot study in Thailand(Grant No.66-P1-0473)The University Pablo de Olavide provided a scholarship for 2 undergraduate students working on the project(codes PPI2207 and PPI2308)In the Czech Republicthe study was supported by Palacky University IGA(Grant No.IGA_FTK_2023_017)supported by the Division of Intramural Research at the National Institute on Minority Health and Health Disparities of the National Institutes of Healthsupported by the Key Project of the National Philosophy and Social Science Foundation of China(23&ZD197)。
文摘Background:Investigators from low-,middle-,and high-income countries representing 6 continents contributed to the development of the Global Adolescent and Child Physical Activity Questionnaire(GAC-PAQ).The GAC-PAQ is designed to assess physical activity(PA)across all key domains(i.e.,school,chores,work/volunteering,transport,free time,outdoor time).It aimed to address multiple gaps in global PA surveillance(e.g.,omission of important PA domains,insufficient cultural adaptation,underrepresentation of rural areas in questionnaire validation studies).The purpose of this study was to assess the content validity of the GAC-PAQ among PA experts,8-to 17-year-olds,and one of their parents/guardians,and to discuss changes made to the questionnaire based on participants'feedback.Methods:Sixty-two experts in PA measurement and/or surveillance from 24 countries completed an online survey that included both closed-and open-ended questions about the content validity of the GAC-PAQ.The proportion of experts who agreed or strongly agreed with the items was calculated.Child-parent/guardian dyads from 15 countries(n=250;10-40 per country)participated in a structured cognitive interview to assess the clarity of the questions and response options,and they were encouraged to provide suggestions to improve clarity and facilitate completion of the questionnaire.Participating countries are:Aotearoa New Zealand,Brazil,Canada,China,Colombia,Czech Republic,India,Malawi,Mexico,Nepal,Nigeria,Spain,Sweden,Thailand,and the United Arab Emirates.Interviews were conducted in 13 different languages and structured by PA domain.Generic images were included to help participants in answering questions about PA intensity.Results:Expert agreement with the items for each domain exceeded 75%,and their qualitative feedback was used to revise the questionnaire before cognitive interviews.In general,participants found the questionnaire to be comprehensive.Adolescents(12-17 years)found it easier than children(8-11 years)to answer the questions.Several children struggled to answer questions about the duration and intensity of activities and/or concepts related to travel modes,active trips,and organized activities.Many parents/guardians were unsure about the frequency,duration,and intensity of their children's or adolescents'PA at school and/or recommended using more culturally relevant and appropriate images.Some participants misunderstood the concept of activities that“make you stronger”(intended to assess resistance activities)and/or struggled to differentiate between work,volunteering,and chores.Conclusion:Participants'feedback was used to develop a revised,simplified,and culturally adapted GAC-PAQ,which will be pilot-tested in all15 countries in an App that will include country-specific images and narration in local languages.Further research is needed to assess the reliability and validity of the revised GAC-PAQ.
文摘This study examines the reliability and validity of AI-generated scoring for continuation writing tasks.By comparing GPT-4 with eight experienced human raters across 21 student responses,it evaluates AI’s consistency,severity,and alignment with human scoring criteria.Results show that AI exhibits high self-consistency and adapts effectively to different scoring roles(e.g.,teacher vs.highstakes rater).However,AI scores were more lenient than human raters and demonstrated divergent evaluation focuses—prioritizing narrative coherence and emotional depth,while teachers emphasized linguistic accuracy and richness of detail.The findings suggest AI’s potential as a supplementary assessment tool,offering rapid,holistic feedback,but highlight the need for further calibration to align with educational standards.Implications include exploring hybrid evaluation models that leverage the strengths of both AI and human raters to achieve more equitable,efficient,and pedagogically meaningful writing assessments.
文摘Background:The World Health Organization Disability Assessment Schedule 2.0(WHODAS 2.0)is a popular tool for eval-uating functioning and disability in a range of population demographics and medical situations.However,very little is known about the WHODAS 2.0's validity and reliability,particularly when dealing with potentially life-threatening maternal condi-tions(PLTCs).The aim of this study was to evaluate the validity of the WHODAS 2.0 Tigrigna version.Methods:This cross-sectional study was conducted in Tigray,northern Ethiopia,from December 15 to 20,2023.Following translation and back translation,women who had experienced PLTCs during a recent pregnancy,childbirth,or postpartum period were administered the 36-item WHODAS 2.0 in Tigrigna version 6 months after the childbirth.In total,121 women with a history of PLTCs participated.Cronbach′sαwas used to evaluate internal consistency in all six WHODAS 2.0 domains,while Spearman′s correlation coefficient was used to evaluate convergent validity.With confirmatory factor analysis,construct validity was also examined.Results:All domain scores of the Tigrigna version of the WHODAS 2.0 indicated excellent internal consistency(α=0.917-0.978 for 36 items andα=0.874-0.940 for 12 items),while the Cronbach′sαcoefficients for the summary score were 0.981 and 0.952 for 36 and 12 items,respectively.The convergent validity between the 36-item and 12-item WHODAS 2.0 showed a strong correlation between similar constructs(r=0.909-0.981).Conclusion:Despite the small sample limitation,the WHODAS 2.0 tool adapted to the Tigrigna version indicated an acceptable reliability and validity and therefore could be applied to women with a history of PLTCs at 6 months postpartum.
基金supported by the DH2025-TN07-07 project conducted at the Thai Nguyen University of Information and Communication Technology,Thai Nguyen,Vietnam,with additional support from the AI in Software Engineering Lab.
文摘It remains difficult to automate the creation and validation of Unified Modeling Language(UML)dia-grams due to unstructured requirements,limited automated pipelines,and the lack of reliable evaluation methods.This study introduces a cohesive architecture that amalgamates requirement development,UML synthesis,and multimodal validation.First,LLaMA-3.2-1B-Instruct was utilized to generate user-focused requirements.Then,DeepSeek-R1-Distill-Qwen-32B applies its reasoning skills to transform these requirements into PlantUML code.Using this dual-LLM pipeline,we constructed a synthetic dataset of 11,997 UML diagrams spanning six major diagram families.Rendering analysis showed that 89.5%of the generated diagrams compile correctly,while invalid cases were detected automatically.To assess quality,we employed a multimodal scoring method that combines Qwen2.5-VL-3B,LLaMA-3.2-11B-Vision-Instruct and Aya-Vision-8B,with weights based on MMMU performance.A study with 94 experts revealed strong alignment between automatic and manual evaluations,yielding a Pearson correlation of r=0.82 and a Fleiss’Kappa of 0.78.This indicates a high degree of concordance between automated metrics and human judgment.Overall,the results demonstrated that our scoring system is effective and that the proposed generation pipeline produces UML diagrams that are both syntactically correct and semantically coherent.More broadly,the system provides a scalable and reproducible foundation for future work in AI-driven software modeling and multimodal verification.
基金supported by the National Natural Science Foundation of China(82330042,82441005 and 82301687)the National Key R&D Program of China(2023YFE0119400)+9 种基金the Capital’s Funds for Health Improvement and Research(2024-1-4111)the STI2030-Major Projects-2021ZD0200702Fundamental Research Funds for the Central Universities(Peking University Medicine Fund for world’s leading discipline or discipline cluster development,BMU2022DJXK007)the Beijing Municipal Health Commission Research Ward Programme(3rd batch)Beijing Nova Program(20230484425)the Beijing Municipal Science&Technology Commission,Administrative Commission of Zhongguancun Science Park(Z221100003522010)the China Postdoctoral Science Foundation(2024M760141 and 2022M720302)the National Postdoctoral Program for Innovative Talents(BX20240029)the Beijing Natural Science Foundation(7254462)the Peking University Medicine Sailing Program for Young Scholars’Scientific&Technological Innovation,the Fundamental Research Funds for the Central Universities(BMU2025YFJHPY044 and BMU2025YFJHPY046).
文摘Background:Antipsychotic-induced movement disorders(AIMDs)are prevalent side effects of antipsychotics,particularly during the acute phase of treatment.This study aimed to elucidate the genetic mechanisms underlying AIMDs using a genome-wide association study(GWAS).Methods:GWASs on AIMDs were conducted in three independent cohorts:a discovery cohort of 3067 patients(2016 subjects were reserved after quality control),a validation cohort of 277 patients,and a multi-ancestry validation cohort of 766 patients.Subsequent post-GWAS analyses included gene-based analyses,transcriptome-wide association studies(TWASs),and polygenic risk score(PRS)profiling.Results:Our study identified two loci located in RAB44 gene(rs116249243,P=5.98×10^(-9);rs117097482,P=1.17×10^(-8))associated with extrapyramidal symptoms(EPSs),1 locus(rs6826172,P=5.56×10^(-9))related to akathisia,and 76 loci linked to involuntary movements(11 genes were mapped).Risk loci located in CNTNAP2,LUZP2,TMEM167A,and RAB44 genes were successfully replicated in the validation cohort,whereas the locus located in RAB44 was also replicated in the multi-ancestry cohort.Gene-based analyses indicated that XRCC4 and PAIP2B reached significance at the genome-wide level in involuntary movements.Tissue expression analysis revealed that involuntary movement-related genes are predominantly expressed in the substantia nigra.Additionally,the TWAS suggested a causal relationship between XRCC4 and involuntary movement.The PRSs derived from the discovery cohort significantly predicted AIMDs in the validation cohort,with area under the receiver operating characteristic curve(AUC)values from 0.60 to 0.80.Conclusions:Our findings highlight the role of substantia nigra related gene polymorphisms in AIMDs.This study provides novel insights into the pathogenesis of AIMDs and supports the potential for personalized treatment approaches for schizophrenia.
基金supported by the National Natural Science Foundation of China(No.82371530,82171529)the Capital Health Development Special Research Project(2022-1-4111)the National Key Technology R and D Program(No.2015BAI13B01).
文摘Background The patient-reported Dimensional Anhedonia Rating Scale(DARS)has been adapted into Chinese,so there is a need to evaluate its measurement properties in a Chinese population.Aims To evaluate the reliability and validity of the DARS among Chinese individuals with major depressive disorder(MDD)and its treatment sensitivity in a prospective clinical study.Methods Data were from a multicentre,prospective clinical study(NCT03294525),which recruited both patients with MDD,who were followed for 8 weeks,and healthy controls(HCs),assessed at baseline only.The analysis included confirmatory factor analysis,validity and sensitivity to change.Results Patients’mean(standard deviation(SD))age was 34.8(11.0)years,with 68.7%being female.75.2%of patients with MDD had melancholic features,followed by 63.8%with anxious distress.Patients had experienced MDD for a mean(SD)of 9.2(18)months.DARS scores covered the full range of severity with no major floor or ceiling effects.Confirmatory factor analysis showed adequate fit statistics(comparative fit index 0.976,goodness-of-fit index 0.935 and root mean square error of approximation 0.055).Convergent validity with anhedonia-related measures was confirmed.While the correlation between the DARS and the Hamilton Depression Rating Scale was not strong(r=0.31,baseline),the DARS was found to differentiate between levels of depression.Greater improvements in DARS scores were seen with the Hamilton Rating Scale for Depression responder group(effect size 1.16)compared with the non-responder group(effect size 0.46).Conclusions This study comprehensively evaluated the measurement properties of the DARS using a Chinese population with MDD.Overall,the Chinese version of DARS demonstrates good psychometric properties and has been found to be responsive to change during antidepressant treatment.The DARS is a suitable scale for assessing patient-reported anhedonia in future clinical trials.
基金Supported by SEDENA Budgetary Program,No.A022-2021.
文摘The process of selecting an artificial intelligence(AI)model to assist clinical diagnosis of a particular pathology and its validation tests is relevant since the values of accuracy,sensitivity and specificity may not reflect the behavior of the method in a real environment.Here,we provide helpful considerations to increase the success of using an AI model in clinical practice.
基金funded in part by the German Research Foundation(Grant reference:496846758).
文摘The ongoing revolution in information technology is reshaping human life. In the realm of health behavior, wearable technology emerges as a leading digital solution,capturing physical behaviors (i.e., physical activity, sedentary habits, sleep patterns) within the 24-h cycle of daily life. Wearables are applied in research, clinical practice, and as lifestyle devices;most obvious, they promise to be a key element for increasing human physical activity, one of the biggest health challenges nowadays.
基金The National Natural Science Foundation of China(No.52278189)Zhejiang Provincial Natural Science Foundation of China(No.LY24E080002).
文摘A self-centering bridge bent equipped with energy-dissipation(ED)beams is proposed.Quasi-static tests are conducted on self-centering bridge bents,both with and without ED beams,to validate the accuracy of the corresponding numerical models.The effects of various param-eters,such as the web area of ED beams,prestressing force of tendons,tendon arrangements,and number of column segments,on the seismic performance of self-centering bridge bents with ED beams are evaluated using the validated numerical model.The results demonstrate that the nu-merical models accurately replicate the quasi-static test results,with average errors in the lateral force remaining below 9.6%.The web area of ED beams significantly affects the strength,cumulative energy dissipation,and relative self-centering index(RSI)of the self-centering bridge bents.Increasing the prestressing force enhances the lateral force and self-centering capability of the bridge bents but has minimal effect on their ED capacity.Reducing the num-ber of segments in each column enhances the lateral force and cumulative hysteretic energy dissipation of the self-centering bridge bents while exerting an insignificant effect on the RSI.Thus,the proposed novel system is highly suitable for doubleor multicolumn piers supporting bridges in regions prone to strong earthquakes.
基金Shanghai Clinical Research Center for Chronic Musculoskeletal Diseases (20MC1920600)Shanghai Key Clinical Specialty "Traditional Chinese Medicine Orthopaedic Traumatology"(shslczdzk03901)+3 种基金The Second Round of Construction Project of National TCM Academic School Inheritance Studio "Shi's Trauma Department"[Letter of the People's Education of Traditional Chinese Medicine (2019) No.62]Shanghai High-level Local Universities "Chronic Muscle and Bone Damage Research and Transformation" Innovation Team [No.3 of Shanghai Education Commission (2022)]Program for Shanghai High-Level Local University Innovation Team (SZY20220315)Shanghai Shenkang Hospital Development Center Clinical Three-year Action Plan (SHDC2020CR3090B)。
文摘OBJECTIVE:To explore the potential molecular mechanism of Qigu capsule(芪骨胶囊,QGC) in the treatment of sarcopenia through network pharmacology and to verify it experimentally.METHODS:The active compounds of QGC and common targets between QGC and sarcopenia were screened from databases.Then the herbs-compounds-targets network,and protein-protein interaction(PPI) network was constructed.Gene ontology(GO) and Kyoto Encyclopedia of Genes and Genomes(KEGG) pathway enrichment analysis were performed by R software.Next,we used a dexamethasone-induced sarcopenia mouse model to evaluate the anti-sarcopenic mechanism of QGC.RESULTS:A total of 57 common targets of QGC and sarcopenia were obtained.Based on the enrichment analysis of GO and KEGG,we took the phosphatidylinositol 3-kinase(PI3K)/protein kinase B(Akt) signaling pathway as a key target to explore the mechanism of QGC on sarcopenia.Animal experiments showed that QGC could increase muscle strength and inhibit muscle fiber atrophy.In the model group,the expression of muscle ring finger-1 and Atrogin-1 were increased,while myosin heavy chain was decreased,QGC treatment reversed these changes.Moreover,compared with the model group,the expressions of pPI3K,p-Akt,p-mammalian target of rapamycin and pForkhead box O3 in the QGC group were all upregulated.CONCLUSION:QGC exerts an anti-sarcopenic effect by activating PI3K/Akt signaling pathway to regulate skeletal muscle protein metabolism.
基金supported by the Natural Science Foundation of Hunan Province(2024JJ6626)the Hunan Provincial Key Laboratory of Regional Hereditary Birth Defects Prevention and Control(HPKL202320),China.
文摘Objective:Pelvic floor dysfunction is common among pregnant and postpartum women and significantly impacts quality of life.This study aims to translate the German Pelvic Floor Questionnaire for Pregnant and Postpartum Women into Chinese and to evaluate its reliability and validity in the Chinese population.Methods:The questionnaire was translated using the Brislin model.A cross-sectional study was conducted among pregnant and postpartum women to assess the content validity,construct validity,Cronbach’sαcoefficient,test-retest reliability,and split-half reliability of the Chinese version.Results:A total of 72 women were included,with 6.9% being pregnant and 93.1% postpartum;the age was(32.3±3.6)years.The Chinese version of the questionnaire contains 4 dimensions and 45 items.The content validity index of individual items ranged from 0.833 to 1.000,with a scale-level content validity index of 0.977 and intraclass correlation coefficients(ICCs)exceeding 0.90.The overall Cronbach’s α coefficient was 0.891,with subscale coefficients ranging from 0.732 to 0.884(all ICCs>0.70).The testretest reliability of the total scale was 0.833,and for the 4 dimensions,bladder,bowel,prolapse,and sexual function,the values were 0.776,0.579,0.732,and 0.645,respectively.The split-half reliability was 0.74.Conclusion:The Chinese version of the questionnaire demonstrated good reliability and validity,indicating its applicability in assessing pelvic floor dysfunction and associated risk factors during pregnancy and postpartum.
文摘The purpose of this paper is to look into how reliable and valid the Persian version of the Cannabis Use Disorder Identification Test-Revised (CUDIT-R-Pr) is. It will also compare the screening features of the CUDIT-R with those of the DSM-5 criteria for cannabis use disorder (CUD) based on the SCID-5-CT in a group of university students in Tehran, Iran. The study used the stratified random sampling technique to collect data from 541 students (19 to 24 years old) who used cannabis in Tehran universities in 2024. Confirmatory factor analysis confirmed the uni-dimensionality of the CUDIT-R-Pr. We checked the reliability of the CUDIT-R-Pr using Cronbach Alpha, split-half, inter-rater, test-retest stability over time, and parallel testing equivalence. The results indicated that CUDIT-R-Pr is reliable, reproducible, and responsive, with substantial agreement and adequate interpretability. The CUDIT-R shows that it can tell the difference between different levels of cannabis use severity, which is known as discriminant validity. Receiver operating characteristic analyses confirmed this, using an area under the receiver operating characteristics curve (AUC = 0.95) at a cutoff of ten or less. This allowed CUDIT-R-Pr to accurately predict any DSM-5 based on the highest correctly classified value (0.89), demonstrating high levels of sensitivity (0.96), specificity (0.69), and Youden value (0.65). The exact maximum Youden index (0.72) showed that CUDIT-R-Pr could also predict moderate DSM-5 with a cutoff of twelve or less. To validate and generalize the CUDIT-R-Pr for use among Iranian cannabis users, we need more research.
文摘Objectives This study aimed to validate the Russian version of the Copenhagen Burnout Inventory(R-CBI)among nurses in Kazakhstan and Kyrgyzstan and explored factors contributing to burnout.Methods The original Copenhagen Burnout Inventory(CBI)was translated into the R-CBI using a rigorous forward-backward method and reviewed by experts.Between July and November 2022,1,530 nurses were recruited through convenience sampling method from various nursing settings in Kazakhstan and Kyrgyzstan to test the scale’s reliability and validity,including confirmatory factor analysis(CFA),internal consistency reliability,and concurrent validity.A linear regression analysis was conducted to identify influencing factors of burnout.Results The content of the R-CBI is consistent with the original CBI,consisting of 19 items with three dimensions.The Cronbach’sαcoefficient is 0.926 in Kazakhstan and 0.922 in Kyrgyzstan,ranging from 0.830 to 0.898 for three dimensions.The CFA results among nurses in Kazakhstan and Kyrgyzstan supported the three-factor structure of R-CBI with good fit indices.Concurrent validity was established through significant correlations(P<0.001)with job satisfaction questionnaire(r=−0.457),Depression Anxiety Stress Scales(r=0.506 in depression,r=0.485 in anxiety,r=0.564 in stress),and WHO-5 Well-Being Index(r=−0.528).The overall burnout level was 36.1±17.6 and 37.5±17.4 in Kazakhstani and Kyrgyzstani nurses,respectively.Significant influencing factors of burnout included gender,age,educational level,and COVID-19 infection history.Conclusions The R-CBI was proved to be a reliable and valid tool for assessing nurses’burnout in Kazakhstan and Kyrgyzstan.
文摘BACKGROUND During the gradual decline of physical and social functioning associated with end-stage renal disease,patients might experience a premonition of impending death,resulting in a series of pre-mourning grief responses called preparatory grief.The preparatory grief in advanced cancer patients(PGAC)scale is the most widely used preparatory grief scale for patients on hemodialysis in China.AIM To verify the reliability and validity of the PGAC scale in patients on hemodialysis.METHODS In total,327 patients undergoing regular hemodialysis in the blood purification center of three grade-A tertiary hospitals in Guangdong and Guizhou provinces were selected by convenience sampling.The assessment was administered using the general information questionnaire and the Chinese version of PGAC.SPSS 25.0 and Amos 24.0 were used for item analysis,confirmatory factor analysis(CFA),convergent validity,and internal consistency reliability estimation.RESULTS In the modified Chinese version of PGAC,7 dimensions covering 27 total items were retained.CFA revealed a good fit of the factor model(chi-square degree of freedom=2.056,standardized root mean square residual=0.0479,root mean square error of approximation=0.0570,GFI=0.872,AGFI=0.841,IFI=0.931,CFI=0.930,TLI=0.919).The factor loadings of the items ranged 0.503-0.884.The composite reliability ranged 0.664-0.914,and the average variance extracted ranged 0.366-0.747.Cronbach’sαof the scale was 0.945,and Cronbach’sαfor various dimensions ranged 0.662-0.914.CONCLUSION The modified PGAC has good reliability and validity,and it can effectively measure preparatory grief in patients on hemodialysis.
基金supported by the project Monetary valuation of soil ecosystem services and creation of initiatives to invest in soil health:setting a framework for the inclusion of soil health in business and in the policy making process(InBestSoil)(Horizon Europe)Grant agreement ID:101091099。
文摘Ecosystem services(ES)mapping and models have advanced in recent years.Improvements were made,and the assessments have transitioned from qualitative to quantitative.Although this is an important advancement,the ES mapping and modelling validation step has been overlooked,and this raises an important question in the credibility of the outcomes.This has been an important and unsolved issue in the ES research community that needs to be tackled.This highlight paper discusses the importance of validating single ES mapping and models.Conducting this using field or proximal/remote sensing raw data and not data from other models or stakeholder evaluation is important.A validation step should be mandatory in ES frameworks since it can assess the models’veracity,contribute to identifying the model’s weaknesses/strengths and ultimately represent a scientific advance in the field.This is easier to apply to the biophysical mapping and models of regulating and provisioning ES than to cultural ES,as the latter rely more on perception and cultural contexts.Also,ES supply models are easier to validate than demand and flow models.Robust and well-grounded models are essential for ensuring the reliability of individual ES maps and models and should be integrated into decision-making processes.Although several challenges arise related to the costs of data collection,in several cases prohibitive,and the time and the expertise needed to conduct this sampling and analysis,this is likely an imperative step that needs to be considered in the future.This will be beneficial in establishing ES research and improving decision-making and wellbeing.
文摘BACKGROUND The Victorian institute of sports assessment for patellar tendons questionnaire(VISA-P),a valid tool for patellar tendinopathy,has been used for patellofemoral pain(PFP).AIM To validate VISA-P in PFP.METHODS Study of validity,responsiveness and feasibility following COSMIN.Inclusion criteria:Subjects with PFP,aged 18 to 55.Agreement among 10 experts on the relevance and clarity of each item using Aiken's V coefficient determined content validity.An exploratory factorial analysis established structural validity.The correlation of VISA-P with knee injury and osteoarthritis outcome score for PFP and Osteoarthritis(KOOS-PF)and Kujala patellofemoral score(KPS;specific for PFP)analyzed the construct validity.Internal consistency was calculated with Cronbach'sαand test-retest reliability with the intraclass correlation coefficient(ICC).Feasibility considered the subjects'self-completion time.RESULTS The sample consisted of 103 knees from 73 subjects(47 female/26 male;aged 34.9±13 SD).The items were relevant and clear,with the exception of item-8,which didn't reach an acceptable level of agreement on clarity.Exploratory factorial analysis found a 2-factor solution,which explained 63.48%of the variance.VISAP achieved a strong and significant correlation with KOOS-PF(Spearman rho=0.826;P<0.001)and KPS(Spearman rho=0.771;P<0.001).The questionnaire showed adequate reliability(Cronbach'sα:0.752;ICC:0.934;P<0.0001;95%CI:0.902-0.955).The mean self-completion time was 232±0.52 SD seconds.CONCLUSION VISA-P proved to be valid and reliable to functionally assess PFP and/or chondromalacia patella.VISA-P is a feasible tool in the clinical and research environment,quick and easy to complete.
基金The National Key Research and Development Program of China under contract No.2021YFB3901304the National Natural Science Foundation of China under contract No.42842176181,42476173,and 42176179the Natural Science Foundation of Jiangsu Province under contract No.BK20211289.
文摘Chlorophyll a(Chl a)is a key photosynthetic pigment and an essential indicator of phytoplankton biomass.Accurate Chl a measurements are crucial for understanding marine biogeochemical processes.China launched the Chinese Ocean Color and Temperature Scanner(COCTS)aboard the HY-1D satellite in 2020,yet its Chl a products require further validation in complex coastal waters.This study assesses HY-1D Chl a products in the Bohai and Yellow Seas,two optically complex coastal regions,using in situ data collected during multiple cruises.Additionally,we compare HY-1D Chl a products with those from the Moderate Resolution Imaging Spectroradiometer(MODIS)and the Visible Infrared Imaging Radiometer Suite(VIIRS).We observed that although Chl a products from HY-1D are generally consistent with those from the MODIS and VIIRS in spatial distribution,there are still significant errors when compared with in situ data.Therefore,we developed a new blended algorithm to improve the accuracy of HY-1D Chl a products.The algorithm distinguishes between turbid and relatively clean waters using a classification index based on the ratio of remote sensing reflectance(R_(rs)(λ)).After the initial classification,we developed targeted algorithms based on the optical properties of different water bodies.The new model shows a significant improvement,reducing the mean absolute percentage error(MAPE)from 43.1%to 24.3%.Additionally,merging Chl a data from HY-1D,MODIS,and VIIRS maintains good accuracy,with HY-1D Chl a products significantly enhancing data coverage and robustness.This research provides important support for producing high-quality HY-1D Chl a products for coastal waters.
基金Sichuan Provincial Nursing Research Project of the Sichuan Nursing Association in 2023(Project No.:H23028)。
文摘Objective:This study aims to develop an assessment tool for postoperative wound healing in adult patients with benign anal canal and rectal diseases and to validate its reliability and validity.Methods:Based on Levine’s Conservation Model as the theoretical framework,an item pool was formed through literature review,and the initial draft of the scale was refined through two rounds of Delphi expert consultation.A total of 200 postoperative patients were selected for item analysis,internal consistency testing,content validity,and structural validity analysis.Results:The final tool comprises four dimensions:energy conservation,structural integrity,personal integrity,and social integrity,with a total of 24 items.It demonstrates good content validity(I-CVI 0.82-1.00,S-CVI/Ave 0.95,S-CVI/UA 0.87)and excellent internal consistency(Cronbach’sαfor the overall scale was 0.934).Exploratory factor analysis revealed a KMO value of 0.931,Bartlett’s test of sphericityχ^(2)=4147.853(p<0.001),and four common factors were extracted,accounting for a cumulative variance contribution rate of 64.345%,indicating ideal structural validity.Conclusion:The results indicate that the assessment tool has good reliability and validity and can systematically evaluate postoperative wound healing,providing a scientific basis for clinical individualized nursing interventions.
文摘Objective:This study aimed to translate the de Morton Mobility Index(DEMMI)into Thai and assess its measurement properties.Methods:The de Morton Mobility Index(DEMMI)was translated into Thai using a cross-cultural translation method.A cross-sectional study was conducted in four public hospitals in Thailand between January and March 2023.A total of 260 patients were recruited from outpatient clinics.Convergent and known-group validity were evaluated through hypothesis testing.Construct validity was examined using confirmatory factor analysis.Reliability was assessed using Cronbach’s a coefficient.We also employed the Rasch analysis to validate validity and person reliability.Results:Content validity was high(S-CVI=0.96,I-CVI range:0.80e1.00).Strong convergent validity was observed,with a significant correlation(r=0.761,P<0.001)between the Thai DEMMI and the Parker Mobility Scale(PMS).Known-group validity was evident,demonstrating differences in scores across various patient groups.A confirmatory factor analysis supported the hypothesized factor structure of the Thai DEMMI with good fit indices:χ^(2)(df=4)=5.101,P=0.2771;χ^(2)/df=1.275,RMSEA=0.033;CFI=0.998;TLI=0.995;SRMR=0.016.The Thai DEMMI exhibited high internal consistency(Cronbach’s a=0.88).Rasch analysis revealed good person reliability(0.91)and acceptable information-weighted fit means square statistic(0.73-1.06).However,most items showed good fit based on the outlier-sensitive fit means square statistics(Outfit MNSQ),one exhibited a high Outfit MNSQ value of 29.94,suggesting a potential misfit.Conclusion:This study demonstrated the acceptable validity and reliability of the Thai DEMMI.Further evaluation of its responsiveness to change is still recommended.
