From 26 October to 2 November 2024,Spain experienced a record-breaking rainfall event,with the most intense episode appearing in Valencia Province.During the event,Turis station recorded a historic 24-hour precipitati...From 26 October to 2 November 2024,Spain experienced a record-breaking rainfall event,with the most intense episode appearing in Valencia Province.During the event,Turis station recorded a historic 24-hour precipitation of 710.8 mm,exceeding the national annual average.This resulting flood led to widespread disruption and significant societal impacts.Synoptic analyses reveal that the event was dominated by a deep cut-off low extending through the entire troposphere and persisting for approximately 186 h.Background conditions were characterized by upper-level divergence,mid-tropospheric warm advection,and a strong southeasterly low-level jet,which promoted vertical motion and sustained moisture transport.The steep,funnel-shaped terrain along the eastern Iberian coast further triggered and enhanced the local convection.A 10-day backward Lagrangian moisture tracing using the HYSPLIT model identified the Mediterranean Sea as the primary moisture source(78.1%),followed by northwestern Africa(8.5%)and central-eastern Europe/the Black Sea(6.2%).Low-level moisture transport was mainly driven by the cut-off low and a persistent Mediterranean high,while mid-to upper-level trajectories were associated with a preceding low-pressure system over the Mediterranean and the subtropical Atlantic high.These systems acted in sequence to relay moisture toward the Valencia region,and under the influence of the strongly rotating and convergent cut-off low—along with terrain-induced lifting—this moisture was rapidly uplifted,ultimately triggering the extreme rainfall event.展开更多
BACKGROUND Delta hepatitis is a rare infection with an aggressive disease course.For almost three decades,however,there have been no epidemiological studies in our traditionally endemic area.AIM To investigate the pre...BACKGROUND Delta hepatitis is a rare infection with an aggressive disease course.For almost three decades,however,there have been no epidemiological studies in our traditionally endemic area.AIM To investigate the prevalence of delta hepatitis in a sample of patients with chronic hepatitis B virus(HBV)infection followed at a Hepatology Unit in Valencia,Spain.METHODS Retrospective evaluation of anti-hepatitis D virus-immunoglobulin G seroprevalence among patients with chronic HBV infection(n=605)followed at a reference Hepatology Unit in Spain.RESULTS The prevalence of anti-hepatitis D virus-immunoglobulin G among HBV-infected patients was 11.5%:Male(63%)and median age of 52 years.The majority were born in Spain(67%)and primarily infected through intravenous drug use.However,a significant percent(24.5%),particularly those diagnosed in more recent years,were migrants presumably nosocomially infected.Comorbidities such as diabetes(8.5%),obesity/overweight(55%),and alcohol consumption(34%)were frequent.A high proportion of patients developed liver complications such as cirrhosis(77%),liver decompensation(81%),hepatocellular carcinoma(HCC)(16.5%),or required liver transplantation(LT)(59.5%).Diabetes was associated with progression to cirrhosis,LT,and death.Male sex,increasing age,and alcohol were associated with LT and HCC.Compared to HBV mono-infected patients,delta individuals developed cirrhosis and liver decompensation more frequently,with no differences in HCC rates.CONCLUSION Patients infected in the 1980’s were mostly locals infected through intravenous drug use,whereas those diagnosed recently are frequently non-Spanish natives from endemic areas.Regardless of their origin,patients are predominantly male with significant comorbidities,which potentially play a major role in disease progression.We confirm a high rate of subsequent liver complications.展开更多
Teso subregion in Eastern Uganda is a leading production hub for citrus in Uganda. However, information on fruit quality profile of the three major varieties (Hamlin, Valencia and Washington navel) grown in this regio...Teso subregion in Eastern Uganda is a leading production hub for citrus in Uganda. However, information on fruit quality profile of the three major varieties (Hamlin, Valencia and Washington navel) grown in this region was limited and/or unreported, partly resulting in their limited use for industrial processing. The current study sought to understand the seasonal quality profile of these varieties during the wet and dry seasons for the years 2019, 2022 and 2023. The study was conducted with farmers in the districts of Kumi, Ngora, Soroti and Kalaki. Mature green oranges were periodically harvested and analysed for physical and chemical properties. The results showed that the quality of oranges varied depending on the season at harvest and the variety with significant differences (p ≤ 0.05). Mean weight per fruit was highest in wet season Washington navel (277.5 g) and lowest in dry season Hamlin (149.3 g). Similarly, fruit size varied in the wet season where Washington navel (81.2 mm) had the biggest fruits while dry season Hamlin were smallest (66.6 mm). Dry season Washington navel had had the thickest peel (7.9 mm). Valencia from the wet season had the highest juice content (36.9%) compared to Washington navel (26.5%) from the dry season with the lowest. Titratable acidity was higher in the dry season Valencia (0.9%) compared to the wet season Washington navel and Hamlin (0.3%). Similarly, Total soluble solids (TSS) was higher in the dry season (Washington navel, 10.1 ˚Brix) in contrast to the wet season (Hamlin and Valencia, 7.7 ˚Brix). Valencia had the lowest pH (3.1) however, pH did not vary significantly between season for each variety except for Hamlin. Vitamin C content was higher during the dry season led by Valencia (57.6 mg/100g) and Hamlin (57.4 mg/100g). Sugar to acid ratio was highest during the wet season (Washington navel, 41.5) and lowest in the dry season (Valencia, 17.1). Overall, dry season fruits and more especially Valencia showed versatility in meeting most of the quality requirements for both industrial juice processing and the fresh market. However, there is need to improve the available orange varieties with regard to juice content and optimal sugar: acid ratio regardless of season.展开更多
Giuseppe Stefano出生于意大利中部城市佩斯卡拉(Pescara)的木匠世家,家族专注豪华家具的设计/制造,远近闻名。在于西班牙巴伦西亚大学(Universidad de Valencia)攻读工程学的过程中,他对电影产生了浓厚兴趣。理工男看电影,视角果然与...Giuseppe Stefano出生于意大利中部城市佩斯卡拉(Pescara)的木匠世家,家族专注豪华家具的设计/制造,远近闻名。在于西班牙巴伦西亚大学(Universidad de Valencia)攻读工程学的过程中,他对电影产生了浓厚兴趣。理工男看电影,视角果然与众不同——Giuseppe尝试组建私人影院,吹毛求疵的性格令他遭遇到一大难题:即那些千篇一律,缺乏个性的座椅,让往往需要端坐几个小时甚至大半天看片的他,倍感困惑。展开更多
基金supported by the National Natural Science Foundation of China(42475008)Strategy Priority Research Program of Chinese Academy of Sciences(XDB0760400).
文摘From 26 October to 2 November 2024,Spain experienced a record-breaking rainfall event,with the most intense episode appearing in Valencia Province.During the event,Turis station recorded a historic 24-hour precipitation of 710.8 mm,exceeding the national annual average.This resulting flood led to widespread disruption and significant societal impacts.Synoptic analyses reveal that the event was dominated by a deep cut-off low extending through the entire troposphere and persisting for approximately 186 h.Background conditions were characterized by upper-level divergence,mid-tropospheric warm advection,and a strong southeasterly low-level jet,which promoted vertical motion and sustained moisture transport.The steep,funnel-shaped terrain along the eastern Iberian coast further triggered and enhanced the local convection.A 10-day backward Lagrangian moisture tracing using the HYSPLIT model identified the Mediterranean Sea as the primary moisture source(78.1%),followed by northwestern Africa(8.5%)and central-eastern Europe/the Black Sea(6.2%).Low-level moisture transport was mainly driven by the cut-off low and a persistent Mediterranean high,while mid-to upper-level trajectories were associated with a preceding low-pressure system over the Mediterranean and the subtropical Atlantic high.These systems acted in sequence to relay moisture toward the Valencia region,and under the influence of the strongly rotating and convergent cut-off low—along with terrain-induced lifting—this moisture was rapidly uplifted,ultimately triggering the extreme rainfall event.
文摘BACKGROUND Delta hepatitis is a rare infection with an aggressive disease course.For almost three decades,however,there have been no epidemiological studies in our traditionally endemic area.AIM To investigate the prevalence of delta hepatitis in a sample of patients with chronic hepatitis B virus(HBV)infection followed at a Hepatology Unit in Valencia,Spain.METHODS Retrospective evaluation of anti-hepatitis D virus-immunoglobulin G seroprevalence among patients with chronic HBV infection(n=605)followed at a reference Hepatology Unit in Spain.RESULTS The prevalence of anti-hepatitis D virus-immunoglobulin G among HBV-infected patients was 11.5%:Male(63%)and median age of 52 years.The majority were born in Spain(67%)and primarily infected through intravenous drug use.However,a significant percent(24.5%),particularly those diagnosed in more recent years,were migrants presumably nosocomially infected.Comorbidities such as diabetes(8.5%),obesity/overweight(55%),and alcohol consumption(34%)were frequent.A high proportion of patients developed liver complications such as cirrhosis(77%),liver decompensation(81%),hepatocellular carcinoma(HCC)(16.5%),or required liver transplantation(LT)(59.5%).Diabetes was associated with progression to cirrhosis,LT,and death.Male sex,increasing age,and alcohol were associated with LT and HCC.Compared to HBV mono-infected patients,delta individuals developed cirrhosis and liver decompensation more frequently,with no differences in HCC rates.CONCLUSION Patients infected in the 1980’s were mostly locals infected through intravenous drug use,whereas those diagnosed recently are frequently non-Spanish natives from endemic areas.Regardless of their origin,patients are predominantly male with significant comorbidities,which potentially play a major role in disease progression.We confirm a high rate of subsequent liver complications.
文摘Teso subregion in Eastern Uganda is a leading production hub for citrus in Uganda. However, information on fruit quality profile of the three major varieties (Hamlin, Valencia and Washington navel) grown in this region was limited and/or unreported, partly resulting in their limited use for industrial processing. The current study sought to understand the seasonal quality profile of these varieties during the wet and dry seasons for the years 2019, 2022 and 2023. The study was conducted with farmers in the districts of Kumi, Ngora, Soroti and Kalaki. Mature green oranges were periodically harvested and analysed for physical and chemical properties. The results showed that the quality of oranges varied depending on the season at harvest and the variety with significant differences (p ≤ 0.05). Mean weight per fruit was highest in wet season Washington navel (277.5 g) and lowest in dry season Hamlin (149.3 g). Similarly, fruit size varied in the wet season where Washington navel (81.2 mm) had the biggest fruits while dry season Hamlin were smallest (66.6 mm). Dry season Washington navel had had the thickest peel (7.9 mm). Valencia from the wet season had the highest juice content (36.9%) compared to Washington navel (26.5%) from the dry season with the lowest. Titratable acidity was higher in the dry season Valencia (0.9%) compared to the wet season Washington navel and Hamlin (0.3%). Similarly, Total soluble solids (TSS) was higher in the dry season (Washington navel, 10.1 ˚Brix) in contrast to the wet season (Hamlin and Valencia, 7.7 ˚Brix). Valencia had the lowest pH (3.1) however, pH did not vary significantly between season for each variety except for Hamlin. Vitamin C content was higher during the dry season led by Valencia (57.6 mg/100g) and Hamlin (57.4 mg/100g). Sugar to acid ratio was highest during the wet season (Washington navel, 41.5) and lowest in the dry season (Valencia, 17.1). Overall, dry season fruits and more especially Valencia showed versatility in meeting most of the quality requirements for both industrial juice processing and the fresh market. However, there is need to improve the available orange varieties with regard to juice content and optimal sugar: acid ratio regardless of season.
文摘Giuseppe Stefano出生于意大利中部城市佩斯卡拉(Pescara)的木匠世家,家族专注豪华家具的设计/制造,远近闻名。在于西班牙巴伦西亚大学(Universidad de Valencia)攻读工程学的过程中,他对电影产生了浓厚兴趣。理工男看电影,视角果然与众不同——Giuseppe尝试组建私人影院,吹毛求疵的性格令他遭遇到一大难题:即那些千篇一律,缺乏个性的座椅,让往往需要端坐几个小时甚至大半天看片的他,倍感困惑。
