Evaluation of oral function is useful for tracking longitudinal changes in swallowing function. Using videofluoroscopic(VF) images, we can evaluate swallowing function, but it is extremely difficult to quantitatively ...Evaluation of oral function is useful for tracking longitudinal changes in swallowing function. Using videofluoroscopic(VF) images, we can evaluate swallowing function, but it is extremely difficult to quantitatively evaluate the oral phase. Recently, several studies have tried to quantitatively assess tongue function by analyzing tongue movement on VF images, to measure tongue thickness by ultrasonography, and to measure tongue pressure as surrogate for tongue strength. In this review article,the current state of quantitative assessments of tongue function for identification and management of dysphagia in patients with neuromuscular and other neurological disorders(NNMD) has been outlined. Disturbed bolus transport in patients with NNMD has been quantitatively measured on VF images by analyzing tongue base movement and bolus transport from the mouth to the pharynx. Enlarged tongue in Duchenne muscular dystrophy patients were observed by measuring the transverse width of the tongue on ultrasound. Tongue pressures that were measured using a handheld probe in NNMD patients were less than half of those in healthy subjects. More studies are needed to develop guidelines what types of tongue dysfunction give an indication of adjusting diet and introducing tube feeding to NNMD patients.展开更多
Swallowing impairments,such as dysphagia,pose significant health risks,including aspiration pneumonia,especially in vulnerable populations like infants and the elderly.Traditional diagnostic methods like videofluorosc...Swallowing impairments,such as dysphagia,pose significant health risks,including aspiration pneumonia,especially in vulnerable populations like infants and the elderly.Traditional diagnostic methods like videofluoroscopy and Fiberoptic Endoscopic Evaluation of Swallowing have limitations,including radiation exposure and discomfort.This study explores the potential of photoacoustic imaging as a non-invasive alternative for detecting swallowing events.Utilizing a 10 mg/mL charcoal solution as a contrast agent,we conducted both ex-vivo and in-vivo experiments using pig models.The ex-vivo tests on pig cadavers validated the system’s ability in detecting charcoal flow in the airway.Subsequent in-vivo experiments on live pigs,conducted with synchronized videofluoroscopy,demonstrated photoacoustic’s potential in seeing the same structure as videofluoroscopy.Our preliminary investigation indicates that photoacoustic imaging could offer a safer,more accurate method for dysphagia assessment,particularly in pediatric settings.展开更多
文摘Evaluation of oral function is useful for tracking longitudinal changes in swallowing function. Using videofluoroscopic(VF) images, we can evaluate swallowing function, but it is extremely difficult to quantitatively evaluate the oral phase. Recently, several studies have tried to quantitatively assess tongue function by analyzing tongue movement on VF images, to measure tongue thickness by ultrasonography, and to measure tongue pressure as surrogate for tongue strength. In this review article,the current state of quantitative assessments of tongue function for identification and management of dysphagia in patients with neuromuscular and other neurological disorders(NNMD) has been outlined. Disturbed bolus transport in patients with NNMD has been quantitatively measured on VF images by analyzing tongue base movement and bolus transport from the mouth to the pharynx. Enlarged tongue in Duchenne muscular dystrophy patients were observed by measuring the transverse width of the tongue on ultrasound. Tongue pressures that were measured using a handheld probe in NNMD patients were less than half of those in healthy subjects. More studies are needed to develop guidelines what types of tongue dysfunction give an indication of adjusting diet and introducing tube feeding to NNMD patients.
基金supported in part by the National Institute of Health under Grant R01EB029596 and Grant R01EB028978.
文摘Swallowing impairments,such as dysphagia,pose significant health risks,including aspiration pneumonia,especially in vulnerable populations like infants and the elderly.Traditional diagnostic methods like videofluoroscopy and Fiberoptic Endoscopic Evaluation of Swallowing have limitations,including radiation exposure and discomfort.This study explores the potential of photoacoustic imaging as a non-invasive alternative for detecting swallowing events.Utilizing a 10 mg/mL charcoal solution as a contrast agent,we conducted both ex-vivo and in-vivo experiments using pig models.The ex-vivo tests on pig cadavers validated the system’s ability in detecting charcoal flow in the airway.Subsequent in-vivo experiments on live pigs,conducted with synchronized videofluoroscopy,demonstrated photoacoustic’s potential in seeing the same structure as videofluoroscopy.Our preliminary investigation indicates that photoacoustic imaging could offer a safer,more accurate method for dysphagia assessment,particularly in pediatric settings.
