《牛津现代英汉双解词典》(增补版)将词条"outlast"[1](P1440)的一个义项及其例证last longer than du-ration和outlasted its usefulness分别译作"比…经久"与"经久耐用"。实际上这是两则明显的误解与...《牛津现代英汉双解词典》(增补版)将词条"outlast"[1](P1440)的一个义项及其例证last longer than du-ration和outlasted its usefulness分别译作"比…经久"与"经久耐用"。实际上这是两则明显的误解与误译。与此相反,它们实应理解为"(某事物因存在或使用时间超过特定期限而)不再经久"(no longer last or exist)和"不再有用"(be no longer useful)。文章从语言的连续统(continuum)视角对相关理据作了客观分析与可能探索,兼及双语词典翻译的相关原则问题。展开更多
BACKGROUND Cognitive decline is common among older patients with cardiovascular disease(CVD) and can decrease their self-management abilities. However, the instruments for identifying mild cognitive impairment(MCI) ar...BACKGROUND Cognitive decline is common among older patients with cardiovascular disease(CVD) and can decrease their self-management abilities. However, the instruments for identifying mild cognitive impairment(MCI) are not always feasible in clinical practice. Therefore, this study evaluated whether MCI could be detected using the Japanese version of the Rapid Dementia Screening Test(RDST-J), which is a simple screening tool for identifying cognitive decline.METHODS This retrospective single-center study included patients who were ≥ 65 years old and hospitalized because of CVD.Patients with a pre-hospitalization diagnosis of dementia were excluded. Each patient's cognitive function had been measured at discharge using the RDST-J and the Japanese version of the Montreal Cognitive Assessment(Mo CA-J), which is a standard tool for MCI screening. The correlation between the two scores was evaluated using Spearman's rank correlation coefficient. Receiver operating characteristic(ROC) analysis was also to evaluate whether the RDST-J could identify MCI, which was defined as a Mo CA-J score of ≤ 25 points.RESULTS The study included 78 patients(mean age: 77.2 ± 8.9 years). The RDST-J and Mo CA-J scores were strongly correlated(r = 0.835, P < 0.001). The ROC analysis revealed that an RDST-J score of ≤ 9 points provided 75.4% sensitivity and 95.2% specificity for identifying MCI, with an area under the curve of 0.899(95% CI: 0.835-0.964). The same cut-off value was identified when excluding patients with a high probability of dementia(RDST-J score of ≤ 4 points).CONCLUSIONS The RDST-J may be a simple and effective tool for identifying MCI in older patients with CVD.展开更多
This investigation was aimed to assess the usefulness of delayed hepalobillary Imaging in the diagnosis of small hepatocellular carcinoma (HCC). Sixty-two patients with this hepatic cancer were Included in the study. ...This investigation was aimed to assess the usefulness of delayed hepalobillary Imaging in the diagnosis of small hepatocellular carcinoma (HCC). Sixty-two patients with this hepatic cancer were Included in the study. 56 males and 6 females, with a mean age of 50. 6 yr. (32 - 72 years old). All patients were performed by surgery, verified histologically, and these tumors were smaller than 5 cm. Liver scans were performed 5 minutes, 2 hours and 5 hours after the administration of radlopharmaceutices. In 31 of the 62 patients (50%), the tumor exhibited equal radioactivity uptake or greater radioactivity uptake than the surrounding liver in delayed imaging. And the sensitivity was 33. 3% (2/6), 41.2% (7/17), 60.0% (9/15) and 54.2% (13/24) In the tumor size was ≤2 cm, 2-3cm, 3-4 cm and 4 - 5 cm, respectively. The smallest mass to be detected was only 1. 2 cm. The uptake of radiopharmaceutic was nonsignificantly related to serum AFP level and hepatic cirrhosis (P>0. 05). These results show that 99-Tc-PMT delayed hepatobiliary imaging can be useful in the diagnosis of small hepatocellular carcinoma.展开更多
Nowadays, many scholars would like to use evidence derived from elicitation and introspection in their research. Both elicitation and introspection are common methods of data collection. The essay discusses the useful...Nowadays, many scholars would like to use evidence derived from elicitation and introspection in their research. Both elicitation and introspection are common methods of data collection. The essay discusses the usefulness and pitfall of elicitation and introspection. It finds out that both elicitation and introspection have their own advantages and disadvantages.展开更多
Aim: The purpose of this study was to develop a scale, “parental anxiety about pediatric emergency medical care services” (PAPEMCS), and to evaluate its psychometric properties. Methods: Participants were 14,510 par...Aim: The purpose of this study was to develop a scale, “parental anxiety about pediatric emergency medical care services” (PAPEMCS), and to evaluate its psychometric properties. Methods: Participants were 14,510 parents with children 6 years old or younger in Kagawa Prefecture. Using each half of the participants, exploratory factor analysis was performed to generate items and factors for the PAPEMCS, and confirmatory factor analysis (CFA) was used to establish the construct validity. The generalizability of the PAPEMCS was evaluated by congruence tests and multigroup CFA. The usefulness of the PAPEMCS was established by the relationship between the PAPEMCS and non-urgent usage of pediatric emergency medical care services (PEMCS). Results: The PAPEMCS compromised 4 factors: “anxiety about quality of PEMCS”, “anxiety about PEMCS system”, “anxiety about public support”, and “anxiety about private support”. All reliability estimates (polychoric ordinal alpha coefficients, item-rest correlations), the item discrimination, 5 fit indices for CFA, the convergent validity (indicator reliabilities, composite reliabilities, average variance extracteds), and the discriminant validity fulfilled the acceptability thresholds. All generalizability estimates fulfilled the predetermined levels of acceptability (Tucker’s congruence coefficients, congruence tests, strict factorial invariance). The usefulness of the PAPEMCS was established by the higher scores of the PAPEMCS being related to non-urgent usage of PEMCS. Conclusions: The PAPEMCS demonstrated satisfactory reliability, validity, generalizability and usefulness. The PAPEMCS is useful to quantify the contents and extent of parental anxiety about PEMCS, and to clarify the mechanisms of non-urgent PEMCS usage.展开更多
In making purchasing decisions, consumers look to online reviews posted by others who have used or experienced the product/service. Most existing studies on online reviews only focused on their content without address...In making purchasing decisions, consumers look to online reviews posted by others who have used or experienced the product/service. Most existing studies on online reviews only focused on their content without addressing how their explanation type influences purchasing decisions, not to mention the boundary conditions for such effects. Based on three experimental studies, this paper examines how explanation type affects the perceived usefulness of online reviews and purchasing decisions, and discusses the boundary conditions for such effects. Our findings show that positive explanation type has a positive effect on the perceived usefulness of online reviews, while negative explanation has an insignificant impact. For search products, there is a positive correlation between the online reviews of explained actions and the perceived usefulness of consumer reviews. For experience products, there is a positive correlation between the online reviews of explained reactions and the perceived usefulness of consumer reviews. Further research found that temporal distance may moderate the effects of explanation type and product type on the perceived usefulness of online reviews. This study also provides a new approach for research on the word-of-mouth(WOM) with meaningful implications for e-commerce firms.展开更多
This study investigates the perceived usefulness of selected accounting information presented in the financial statements of small- and medium-sized enterprises （SMEs）. Mailed questionnaires were sent to SMEs＇ owne...This study investigates the perceived usefulness of selected accounting information presented in the financial statements of small- and medium-sized enterprises （SMEs）. Mailed questionnaires were sent to SMEs＇ owner and loan officers in Malaysia. The findings show that the SMEs＇ owners and loan officers have substantially similar views on the usefulness of the accounting information. In addition, this study has found that the academic qualification and time spent in reading the financial statement have significant relationships with the SMEs＇ owners＇ perceptions on the usefulness of the SMEs＇ accounting information, whereas types of business organization, awareness about financial reporting regulation, and level of understanding of the financial statements do not. On the other hand, for the loan officers, accouting expertise, year in position, and awareness about the financial reporting regulation do not have a significant relationship with the loan officers＇ perceptions on the usefulness of the SMEs＇ accounting information. Meanwhile, experience in assessing SMEs＇ financial statements has a significantly negative relationship with the loan officers＇ perceptions on the usefulness of the SMEs＇ accounting information. The results of this study may enable the SMEs＇ managers to realize the informational needs of the users of their financial statements.展开更多
There are many arguments about Hume in the history of philosophy,especially after Kant criticized Hume,Kant believed that there is no concept of“universality”in Hume’s ethics.By analyzing Hume’s text,this article ...There are many arguments about Hume in the history of philosophy,especially after Kant criticized Hume,Kant believed that there is no concept of“universality”in Hume’s ethics.By analyzing Hume’s text,this article points out that Hume also pursues“universality”,and his“universality”is a universality in the sense of usefulness.Not only does his ethics have the concept of universality,but Hume also pursues universality in the field of nature science.This is helpful for the academic community to re-recognize Hume and further promote the study of Hume.展开更多
AIM: To investigate if there is a correlation between electrical activity measured by electrogastrography (EGG) and contractile activity of the stomach as measured by antroduodenal manometry (ADM). We also studied whe...AIM: To investigate if there is a correlation between electrical activity measured by electrogastrography (EGG) and contractile activity of the stomach as measured by antroduodenal manometry (ADM). We also studied whether the underlying motility disorder could be predicted from EGG parameters. METHODS: We compared 21 parameters measured from EGG with 8 parameters measured from ADM. The ability of EGG to identify the underlying diagnosis was tested by comparing EGG parameters for each diagnosis group against other patients. The study comprised recordings from 148 patients and 125 females. Their median age was 45 (range 17-76) years. RESULTS: We found few and weak correlations between EGG and ADM. Specifically the correlation between parameters reflecting the response to meal was poor (r = -0.07, P = 0.39). The discriminatory power of EGG for underlying motility disorder was also low. Patients with slow transit constipation (STC) showed a lower postprandial power in normogastric (3.7 ± 0.5 vs 4.0 ± 0.5) and tachygastric (3.5 ± 0.4 vs 3.7 ± 0.4) regions, a lower percentage of time with normogastria [87.2 (56.5-100)% vs 95.7 (0-100)%], and a higher percentage of time with tachygastria [9.3 (0-33)% vs 3.5 (0-100)%] and bradygastria [1.8 (0-20)% vs 0 (0-17.1)%]. Patients with irritable bowel syndrome had a higher percentage of time with normogastria [96.5 (62.5-100)% vs 93.3 (0-100)%] and a less unstable dominant frequency as measured by the instability coefficient [15 (3-77) vs 24 (2-72)]. CONCLUSION: EGG and ADM seem to measure different aspects of gastric motor activity but cannot show a spatial correlation. The diagnostic value of EGG is poor, but EGG may have some value for the identification of patients with STC.展开更多
Accumulating evidence has highlighted the functional role of the endogenous nociceptin/orphanin FQ peptide(N/OFQ)and its nociceptin opioid receptor(NOP)in alcohol and cocaine reward.However,the effects of NOP agonists...Accumulating evidence has highlighted the functional role of the endogenous nociceptin/orphanin FQ peptide(N/OFQ)and its nociceptin opioid receptor(NOP)in alcohol and cocaine reward.However,the effects of NOP agonists on methamphetamine(MAP)reinforcement,motivation,and relapse remain uncertain.In this study,we evaluated the effects of Ro 64-6198,a selective NOP agonist,on MAP reinforcement,motivation,and relapse in rats.Rats underwent a fixed-ratio 1(FR1)training to establish stable MAP intravenous self-administration(0.05 mg/kg/infusion)for 12 days,and the motivation for MAP was quantified using a progressive-ratio(PR)schedule,while the relapse was assessed through cue-and MAP-primed reinstatement after abstinence.Western blot analysis was employed to measure the relative expression of phosphorylated CREB,ERK,and Akt in the nucleus accumbens(NAc)following drug priming.Acute treatment of Ro 64-6198(1 mg/kg)significantly reduced the motivated behavior for MAP under PR testing(P<0.05 vs.vehicle).Ro 64-6198 at doses of 0.3 and 1 mg/kg could suppress the drug-seeking behavior induced by extinction or cues,respectively(P<0.05),whereas only the higher dose(1 mg/kg)could attenuate MAP primed drug-seeking(P<0.05).These behavioral effects were related to the upregulated phosphorylation of CREB and Akt in the NAc.Our results provide preclinical evidence that NOP activation disrupts multiple addiction-relevant behaviors,positioning Ro 64-6198 as a potential therapeutic candidate for treating MAP use disorders.展开更多
As demand for land resources is rapidly growing nowadays,developing on slope lands has become a way to relieve pressure on flat lands.Although some studies use the concept of slope spectrum to explore the trend of lan...As demand for land resources is rapidly growing nowadays,developing on slope lands has become a way to relieve pressure on flat lands.Although some studies use the concept of slope spectrum to explore the trend of land use upslope,relying solely on the slope spectrum is too broad and prevents deeper research.Therefore,using China's land use and DEM data from 2000 to 2020,our study integrated the slope spectrum and the slope sensitivity coefficient(SSC)calculated by the land use transfer matrix as a new approach and method for understanding the underlying formations and impacts of upslope in farmland and construction land,supporting regional management strategies.The results show that:1)Farmlands were upslope in the South and developed horizontally in the North,and construction lands were upslope nationwide.2)Using the land use transfer matrix and SSC,we classified farmland upslope as passive and active patterns,and construction land upslope as saturation and avoidance patterns based on their land use transfer mechanisms in slope space.Provinces with passive and saturation patterns are mainly located near the east coast.3)Different patterns of upslope have distinct impacts on sustainable development.The passive pattern harms food security while the active pattern can relieve pressure on food security but increases ecological risks.Saturation pattern damages food security,ecological protection,and city livability,but avoidance pattern can promote food security and ecological protection.The findings will serve as an essential reference for developing land use strategies aimed at sustainable development.展开更多
As part of my master’s programme in resource use and environmental science at China Agricultural University,I had the privilege of joining a study trip to the Shiyang River Basin and its surrounding areas from 17 to ...As part of my master’s programme in resource use and environmental science at China Agricultural University,I had the privilege of joining a study trip to the Shiyang River Basin and its surrounding areas from 17 to 21 July 2025.This trip to Gansu Province was organised under the China-Africa Joint Centre for Agricultural Demonstration and Training in Arid Regions programme,an initiative aligned with President Xi Jinping’s call for deeper China-Africa cooperation.展开更多
Understanding the coupling between carbon and water in terrestrial ecosystems is essential for achieving sustainable development.Net primary productivity(NPP),carbon use efficiency(CUE),and water use efficiency(WUE) a...Understanding the coupling between carbon and water in terrestrial ecosystems is essential for achieving sustainable development.Net primary productivity(NPP),carbon use efficiency(CUE),and water use efficiency(WUE) are key indicators for assessing carbon balance and carbon–water interactions.However,knowledge gaps remain regarding how these indicators respond to climate change and interact with one another.This study examined the spatial and temporal dynamics of NPP,CUE,and WUE,as well as their interrelationships,within the Three-North Shelterbelt Forest region of China.Furthermore,the study investigated the driving mechanisms of these indicators using Extreme Gradient Boosting(XGBoost),SHapley Additive ex Planations(SHAP),and Partial Least Squares Structural Equation Modeling(PLS-SEM).The results revealed that from 2000 to 2020,both NPP(2.69 g C/(m^(2)·a);P<0.010) and WUE(0.004 g C/(kg H_(2)O·a);P<0.010) increased significantly,while CUE exhibited a non-significant decline(–5.40×10^(–4)/a;P>0.050) across different climatic zones(arid,semi-arid,humid,and sub-humid) and vegetation types(cropland,forest,grassland,shrubland,and wetland).The correlation between WUE and NPP(correlation coefficient of 0.70) was stronger than that between CUE and NPP(correlation coefficient of 0.15).NPP and WUE were primarily influenced by leaf area index,whereas CUE was most strongly affected by elevation.The relationships between the key drivers and the three indicators were largely nonlinear,with stronger driver contributions corresponding to more pronounced nonlinear interactions.Moreover,these nonlinear relationships were modulated by differences in dry versus wet climatic conditions.Geographical factors(e.g.,longitude,latitude,and elevation) further shaped vegetation characteristics(e.g.,fractional vegetation cover and leaf area index) by regulating climatic variables such as temperature,precipitation,and evapotranspiration,ultimately influencing NPP,WUE,and CUE.This study advances the understanding of vegetation carbon–water coupling and provides a scientific basis for ecosystem management and sustainable development policy-making in various climatic zones.展开更多
The continuous supply of phosphorus(P)is indispensable in crop production.However,P resources are non-renewable,and environmental concerns like eutrophication associated with its loss from agroecosystems make the sust...The continuous supply of phosphorus(P)is indispensable in crop production.However,P resources are non-renewable,and environmental concerns like eutrophication associated with its loss from agroecosystems make the sustainable management of P resources essential for ensuring global food security.This study was designed to reduce mineral P inputs through management practices.A field experiment comprising a wheat-maize rotation system was conducted in the Guanzhong Plain of Shaanxi Province,China from 2018-2023.The eight treatments included CK(without P),FP(conventional P application);RP(recommended P);RP80(20% reduction in RP);SRP80(20% reduction in RP with straw wrapping);ARP80(20% reduction in RP with ammonium sulfate instead of urea);SARP80(20% reduction in RP with straw wrapping and ammonium sulfate instead of urea);and SARP60(40% reduction in RP with straw wrapping and ammonium sulfate instead of urea).Crop yield,P uptake,and P fertilizer use efficiency were measured during harvest and throughout the entire period of the study.At the end of the experiment,P fractions were estimated using the Tiessen-Moir P classification method.The results revealed that the grain yields of all the treatments except for RP80 were significantly increased compared to CK,with increases of 14.9-28.8%.Furthermore,agronomic efficiency,apparent P use efficiency,P recovery rate,and partial factor productivity were significantly improved for the treatments that received 20% less P with straw wrapping.Moreover,the enhancement measures significantly increased labile and moderately labile P in the soil.Therefore,straw wrapping with ammonium sulfate instead of urea is one of the most effective ways to reduce mineral P inputs while increasing the efficiency of P in wheat-maize rotation systems.展开更多
This research offers valuable insights into the relationship between land use and daytime climatic comfort in high-rise urban developments in Delhi.This city is navigating rapid urbanisation and facing critical enviro...This research offers valuable insights into the relationship between land use and daytime climatic comfort in high-rise urban developments in Delhi.This city is navigating rapid urbanisation and facing critical environmental challenges like pollution,heat stress,land degradation etc.The study aims to enhance understanding of how diverse land use patterns influence thermal comfort by utilising satellite data from the Landsat/Resourcesat series for classification and MODIS for land surface temperature(LST)extraction.The findings highlight that regions with dense construction and limited green and blue spaces tend to experience lower levels of climatic comfort,with 17.17 Percent of Delhi’s geographical area feeling the adverse effects of the Urban Heat Island(UHI)phenomenon.On a positive note,40.20 Percent of the area is associated with high climatic comfort,primarily due to natural features such as vegetation and water bodies.Furthermore,the research indicates a noteworthy increase in land surface temperatures(LST)from 2000 to 2022,with peak recorded temperatures rising from 38.35℃ in 2000 to 47.27℃ in 2022.In summary,this study emphasises the importance of understanding and addressing the UHI effect in urban settings,providing constructive recommendations for policymakers and stakeholders dedicated to fostering improved livability and sustainability in urban environments.展开更多
Reconciling biodiversity conservation with economic advancement represents a defining challenge of the Anthropocene epoch.Although ecotourism is widely promoted as a strategy capable of delivering both environmental a...Reconciling biodiversity conservation with economic advancement represents a defining challenge of the Anthropocene epoch.Although ecotourism is widely promoted as a strategy capable of delivering both environmental and developmental benefits,empirical evidence regarding its ecological and socioeconomic impacts remains limited.This study critically examined the Hide-in-Bird Pond(HIBP)model,a rapidly expanding,community-based avitourism framework in China that integrates targeted wildlife provisioning with concealed infrastructure for bird observation,simultaneously establishing a novel income source for economically marginalized rural regions through ecotourism.Semi-structured online interviews were conducted with 98 HIBP operators,and thematic analysis was applied to evaluate current developmental patterns,spatial distribution,and conservation outcomes.A total of 251 HIBP sites were identified across China,predominantly located in biodiversity-rich but economically marginalized regions.These sites collectively supported 524 bird species—36%of China's avifauna—including 148 species classified as nationally protected or threatened(38%of nationally listed bird taxa).These findings suggest that HIBP can serve as an integrative socio-ecological platform that aligns conservation objectives with sustainable rural development.However,the absence of standardized governance frameworks and ecological safeguards poses significant risks to biodiversity an d long-term sustainability.Implementation of science-based adaptive management systems,incorporating systematic biodiversity monitoring,inclusive stakeholder coordination,and certified sustainable tourism protocols,is critical to ensure ecological integrity and sectoral resilience.These findings offer novel insights into aligning conservation objectives with economic development across regions characterized by high biodiversity and persistent economic disadvantage.展开更多
Estuarine and bay ecosystems serve as crucial transitional zones for land-based pollutants entering the ocean.However,there is a critical gap in understanding the behavior of emerging pollutants in the numerous small ...Estuarine and bay ecosystems serve as crucial transitional zones for land-based pollutants entering the ocean.However,there is a critical gap in understanding the behavior of emerging pollutants in the numerous small estuaries and bays located in undeveloped coastal areas.This study provides insights into the fate of antibiotics in these small and scattered estuaries and bays in Shantou's coast,driven by land use types and hydrodynamic conditions.The findings indicated that estuaries were more heavily polluted with antibiotics than the bays(P<0.05),with tetracyclines and fluoroquinolones as the primary antibiotics.Antibiotic pollution levels were more severe in October than in June(P<0.01).Rainfall runoff,aquaculture tailwater,and river discharge were identified as the main sources of antibiotic pollution.Build-up land and aquaculture ponds were the primary land use types contributing to antibiotic pollution.The total antibiotic concentrations in June were positively correlated with the proportion of aquaculture ponds(P<0.05)and negatively correlated with the proportions of cropland and grassland(P<0.05).The concentrations of lomefloxacin and ofloxacin were positively correlated with build-up land.The antibiotic concentrations exhibited strong spatial heterogeneity within both bay and estuarine ecosystems driven by different hydrodynamic conditions.A comparative analysis of global estuaries and bays revealed that specific land-use types and hydrodynamic conditions produced similar trends in antibiotic fate.These insights offered new perspectives to safeguard the health of estuarine and bay ecosystems,such as altering landscape patterns and regulating aquaculture activities.展开更多
Arisaema propinquum(A.propinquum)is a medicinal tuberous plant native to the Himalayan region,belonging to the family Araceae.It has a unique appearance due to its inflorescence,which is strikingly elegant and resembl...Arisaema propinquum(A.propinquum)is a medicinal tuberous plant native to the Himalayan region,belonging to the family Araceae.It has a unique appearance due to its inflorescence,which is strikingly elegant and resembles that of Arisaema triphyllum,also known as“Jack-in-the-pulpit”.This review provides a comprehensive overview of A.propinquum,covering its taxonomy,geographic distribution,and traditional uses.While ethnobotanical information on A.propinquum is relatively well documented,species-specific pharmacological,mechanistic,and in vivo studies remain limited.Accordingly,evidence from related Arisaema species is discussed cautiously as contextual support for phytochemical similarity rather than as direct proof of bioactivity in A.propinquum.This study seeks to establish a relationship between ethnopharmacological use and scientific enquiries into A.propinquum,including a comparison of the various species of the family Araceae and their recent contributions to traditional medicinal advancements.The review mainly emphasises the traditional uses,phytochemistry,safety and toxicity data,and future techniques for its conservation,with increased yield and impact.It highlights A.propinquum as an underexplored yet promising candidate for focused phytochemical characterisation,experimental validation of traditional claims,and conservation-oriented research.Overall,the available evidence indicates that while direct experimental data on the plant remain limited,its placement within a genus rich in bioactive secondary metabolites makes it a strong candidate for focused,species-specific future research.展开更多
Addiction,a complex and chronic neurobiological disorder,is characterized by compulsive substance use despite harmful consequences,leading to persistent alterations in brain function,particularly within the reward,mot...Addiction,a complex and chronic neurobiological disorder,is characterized by compulsive substance use despite harmful consequences,leading to persistent alterations in brain function,particularly within the reward,motivation,and decision-making systems.Despite the availability of a range of treatment options,including pharmacotherapy and behavioral therapies,relapse remains a major challenge,with many individuals struggling to maintain long-term recovery.Current treatments often show limited efficacy,underscoring the need for novel therapeutic strategies that can address the underlying neurobiological disruptions in addiction.展开更多
文摘《牛津现代英汉双解词典》(增补版)将词条"outlast"[1](P1440)的一个义项及其例证last longer than du-ration和outlasted its usefulness分别译作"比…经久"与"经久耐用"。实际上这是两则明显的误解与误译。与此相反,它们实应理解为"(某事物因存在或使用时间超过特定期限而)不再经久"(no longer last or exist)和"不再有用"(be no longer useful)。文章从语言的连续统(continuum)视角对相关理据作了客观分析与可能探索,兼及双语词典翻译的相关原则问题。
文摘BACKGROUND Cognitive decline is common among older patients with cardiovascular disease(CVD) and can decrease their self-management abilities. However, the instruments for identifying mild cognitive impairment(MCI) are not always feasible in clinical practice. Therefore, this study evaluated whether MCI could be detected using the Japanese version of the Rapid Dementia Screening Test(RDST-J), which is a simple screening tool for identifying cognitive decline.METHODS This retrospective single-center study included patients who were ≥ 65 years old and hospitalized because of CVD.Patients with a pre-hospitalization diagnosis of dementia were excluded. Each patient's cognitive function had been measured at discharge using the RDST-J and the Japanese version of the Montreal Cognitive Assessment(Mo CA-J), which is a standard tool for MCI screening. The correlation between the two scores was evaluated using Spearman's rank correlation coefficient. Receiver operating characteristic(ROC) analysis was also to evaluate whether the RDST-J could identify MCI, which was defined as a Mo CA-J score of ≤ 25 points.RESULTS The study included 78 patients(mean age: 77.2 ± 8.9 years). The RDST-J and Mo CA-J scores were strongly correlated(r = 0.835, P < 0.001). The ROC analysis revealed that an RDST-J score of ≤ 9 points provided 75.4% sensitivity and 95.2% specificity for identifying MCI, with an area under the curve of 0.899(95% CI: 0.835-0.964). The same cut-off value was identified when excluding patients with a high probability of dementia(RDST-J score of ≤ 4 points).CONCLUSIONS The RDST-J may be a simple and effective tool for identifying MCI in older patients with CVD.
文摘This investigation was aimed to assess the usefulness of delayed hepalobillary Imaging in the diagnosis of small hepatocellular carcinoma (HCC). Sixty-two patients with this hepatic cancer were Included in the study. 56 males and 6 females, with a mean age of 50. 6 yr. (32 - 72 years old). All patients were performed by surgery, verified histologically, and these tumors were smaller than 5 cm. Liver scans were performed 5 minutes, 2 hours and 5 hours after the administration of radlopharmaceutices. In 31 of the 62 patients (50%), the tumor exhibited equal radioactivity uptake or greater radioactivity uptake than the surrounding liver in delayed imaging. And the sensitivity was 33. 3% (2/6), 41.2% (7/17), 60.0% (9/15) and 54.2% (13/24) In the tumor size was ≤2 cm, 2-3cm, 3-4 cm and 4 - 5 cm, respectively. The smallest mass to be detected was only 1. 2 cm. The uptake of radiopharmaceutic was nonsignificantly related to serum AFP level and hepatic cirrhosis (P>0. 05). These results show that 99-Tc-PMT delayed hepatobiliary imaging can be useful in the diagnosis of small hepatocellular carcinoma.
文摘Nowadays, many scholars would like to use evidence derived from elicitation and introspection in their research. Both elicitation and introspection are common methods of data collection. The essay discusses the usefulness and pitfall of elicitation and introspection. It finds out that both elicitation and introspection have their own advantages and disadvantages.
文摘Aim: The purpose of this study was to develop a scale, “parental anxiety about pediatric emergency medical care services” (PAPEMCS), and to evaluate its psychometric properties. Methods: Participants were 14,510 parents with children 6 years old or younger in Kagawa Prefecture. Using each half of the participants, exploratory factor analysis was performed to generate items and factors for the PAPEMCS, and confirmatory factor analysis (CFA) was used to establish the construct validity. The generalizability of the PAPEMCS was evaluated by congruence tests and multigroup CFA. The usefulness of the PAPEMCS was established by the relationship between the PAPEMCS and non-urgent usage of pediatric emergency medical care services (PEMCS). Results: The PAPEMCS compromised 4 factors: “anxiety about quality of PEMCS”, “anxiety about PEMCS system”, “anxiety about public support”, and “anxiety about private support”. All reliability estimates (polychoric ordinal alpha coefficients, item-rest correlations), the item discrimination, 5 fit indices for CFA, the convergent validity (indicator reliabilities, composite reliabilities, average variance extracteds), and the discriminant validity fulfilled the acceptability thresholds. All generalizability estimates fulfilled the predetermined levels of acceptability (Tucker’s congruence coefficients, congruence tests, strict factorial invariance). The usefulness of the PAPEMCS was established by the higher scores of the PAPEMCS being related to non-urgent usage of PEMCS. Conclusions: The PAPEMCS demonstrated satisfactory reliability, validity, generalizability and usefulness. The PAPEMCS is useful to quantify the contents and extent of parental anxiety about PEMCS, and to clarify the mechanisms of non-urgent PEMCS usage.
基金Supported by"Reputation Sharing Mechanism and Recourse Liability Policy of E-commerce Platform:An Interactive Perspective of Platform Enterprise and Its Sellers"Project of the National Natural Science Foundation of China(NSFC)(Grant No.71672026)"Influencing Mechanism of User-generated Content on Brand Equity of Multichannel Retailers under the Regulatory Focus Paradigm"of the NSFC(Grant No.71272050)
文摘In making purchasing decisions, consumers look to online reviews posted by others who have used or experienced the product/service. Most existing studies on online reviews only focused on their content without addressing how their explanation type influences purchasing decisions, not to mention the boundary conditions for such effects. Based on three experimental studies, this paper examines how explanation type affects the perceived usefulness of online reviews and purchasing decisions, and discusses the boundary conditions for such effects. Our findings show that positive explanation type has a positive effect on the perceived usefulness of online reviews, while negative explanation has an insignificant impact. For search products, there is a positive correlation between the online reviews of explained actions and the perceived usefulness of consumer reviews. For experience products, there is a positive correlation between the online reviews of explained reactions and the perceived usefulness of consumer reviews. Further research found that temporal distance may moderate the effects of explanation type and product type on the perceived usefulness of online reviews. This study also provides a new approach for research on the word-of-mouth(WOM) with meaningful implications for e-commerce firms.
文摘This study investigates the perceived usefulness of selected accounting information presented in the financial statements of small- and medium-sized enterprises （SMEs）. Mailed questionnaires were sent to SMEs＇ owner and loan officers in Malaysia. The findings show that the SMEs＇ owners and loan officers have substantially similar views on the usefulness of the accounting information. In addition, this study has found that the academic qualification and time spent in reading the financial statement have significant relationships with the SMEs＇ owners＇ perceptions on the usefulness of the SMEs＇ accounting information, whereas types of business organization, awareness about financial reporting regulation, and level of understanding of the financial statements do not. On the other hand, for the loan officers, accouting expertise, year in position, and awareness about the financial reporting regulation do not have a significant relationship with the loan officers＇ perceptions on the usefulness of the SMEs＇ accounting information. Meanwhile, experience in assessing SMEs＇ financial statements has a significantly negative relationship with the loan officers＇ perceptions on the usefulness of the SMEs＇ accounting information. The results of this study may enable the SMEs＇ managers to realize the informational needs of the users of their financial statements.
文摘There are many arguments about Hume in the history of philosophy,especially after Kant criticized Hume,Kant believed that there is no concept of“universality”in Hume’s ethics.By analyzing Hume’s text,this article points out that Hume also pursues“universality”,and his“universality”is a universality in the sense of usefulness.Not only does his ethics have the concept of universality,but Hume also pursues universality in the field of nature science.This is helpful for the academic community to re-recognize Hume and further promote the study of Hume.
基金Supported by funds from the Swedish Research Council (grant 2002-5489) and the Swedish Society of Medicine (Ihre’s fond)
文摘AIM: To investigate if there is a correlation between electrical activity measured by electrogastrography (EGG) and contractile activity of the stomach as measured by antroduodenal manometry (ADM). We also studied whether the underlying motility disorder could be predicted from EGG parameters. METHODS: We compared 21 parameters measured from EGG with 8 parameters measured from ADM. The ability of EGG to identify the underlying diagnosis was tested by comparing EGG parameters for each diagnosis group against other patients. The study comprised recordings from 148 patients and 125 females. Their median age was 45 (range 17-76) years. RESULTS: We found few and weak correlations between EGG and ADM. Specifically the correlation between parameters reflecting the response to meal was poor (r = -0.07, P = 0.39). The discriminatory power of EGG for underlying motility disorder was also low. Patients with slow transit constipation (STC) showed a lower postprandial power in normogastric (3.7 ± 0.5 vs 4.0 ± 0.5) and tachygastric (3.5 ± 0.4 vs 3.7 ± 0.4) regions, a lower percentage of time with normogastria [87.2 (56.5-100)% vs 95.7 (0-100)%], and a higher percentage of time with tachygastria [9.3 (0-33)% vs 3.5 (0-100)%] and bradygastria [1.8 (0-20)% vs 0 (0-17.1)%]. Patients with irritable bowel syndrome had a higher percentage of time with normogastria [96.5 (62.5-100)% vs 93.3 (0-100)%] and a less unstable dominant frequency as measured by the instability coefficient [15 (3-77) vs 24 (2-72)]. CONCLUSION: EGG and ADM seem to measure different aspects of gastric motor activity but cannot show a spatial correlation. The diagnostic value of EGG is poor, but EGG may have some value for the identification of patients with STC.
基金supported by Ningbo Top Medical and Health Research Program(No.2022030410)National Key Research and Development Program of China(No.2022YFC3300905,2023YFC3304202).
文摘Accumulating evidence has highlighted the functional role of the endogenous nociceptin/orphanin FQ peptide(N/OFQ)and its nociceptin opioid receptor(NOP)in alcohol and cocaine reward.However,the effects of NOP agonists on methamphetamine(MAP)reinforcement,motivation,and relapse remain uncertain.In this study,we evaluated the effects of Ro 64-6198,a selective NOP agonist,on MAP reinforcement,motivation,and relapse in rats.Rats underwent a fixed-ratio 1(FR1)training to establish stable MAP intravenous self-administration(0.05 mg/kg/infusion)for 12 days,and the motivation for MAP was quantified using a progressive-ratio(PR)schedule,while the relapse was assessed through cue-and MAP-primed reinstatement after abstinence.Western blot analysis was employed to measure the relative expression of phosphorylated CREB,ERK,and Akt in the nucleus accumbens(NAc)following drug priming.Acute treatment of Ro 64-6198(1 mg/kg)significantly reduced the motivated behavior for MAP under PR testing(P<0.05 vs.vehicle).Ro 64-6198 at doses of 0.3 and 1 mg/kg could suppress the drug-seeking behavior induced by extinction or cues,respectively(P<0.05),whereas only the higher dose(1 mg/kg)could attenuate MAP primed drug-seeking(P<0.05).These behavioral effects were related to the upregulated phosphorylation of CREB and Akt in the NAc.Our results provide preclinical evidence that NOP activation disrupts multiple addiction-relevant behaviors,positioning Ro 64-6198 as a potential therapeutic candidate for treating MAP use disorders.
基金funded by the National Natural Science Foundation of China(Grant No.72504262)Natural Science Foundation of Hubei Province of China(Grant No.2024AFB102)。
文摘As demand for land resources is rapidly growing nowadays,developing on slope lands has become a way to relieve pressure on flat lands.Although some studies use the concept of slope spectrum to explore the trend of land use upslope,relying solely on the slope spectrum is too broad and prevents deeper research.Therefore,using China's land use and DEM data from 2000 to 2020,our study integrated the slope spectrum and the slope sensitivity coefficient(SSC)calculated by the land use transfer matrix as a new approach and method for understanding the underlying formations and impacts of upslope in farmland and construction land,supporting regional management strategies.The results show that:1)Farmlands were upslope in the South and developed horizontally in the North,and construction lands were upslope nationwide.2)Using the land use transfer matrix and SSC,we classified farmland upslope as passive and active patterns,and construction land upslope as saturation and avoidance patterns based on their land use transfer mechanisms in slope space.Provinces with passive and saturation patterns are mainly located near the east coast.3)Different patterns of upslope have distinct impacts on sustainable development.The passive pattern harms food security while the active pattern can relieve pressure on food security but increases ecological risks.Saturation pattern damages food security,ecological protection,and city livability,but avoidance pattern can promote food security and ecological protection.The findings will serve as an essential reference for developing land use strategies aimed at sustainable development.
文摘As part of my master’s programme in resource use and environmental science at China Agricultural University,I had the privilege of joining a study trip to the Shiyang River Basin and its surrounding areas from 17 to 21 July 2025.This trip to Gansu Province was organised under the China-Africa Joint Centre for Agricultural Demonstration and Training in Arid Regions programme,an initiative aligned with President Xi Jinping’s call for deeper China-Africa cooperation.
基金the National Natural Science Foundation of China (42171124)。
文摘Understanding the coupling between carbon and water in terrestrial ecosystems is essential for achieving sustainable development.Net primary productivity(NPP),carbon use efficiency(CUE),and water use efficiency(WUE) are key indicators for assessing carbon balance and carbon–water interactions.However,knowledge gaps remain regarding how these indicators respond to climate change and interact with one another.This study examined the spatial and temporal dynamics of NPP,CUE,and WUE,as well as their interrelationships,within the Three-North Shelterbelt Forest region of China.Furthermore,the study investigated the driving mechanisms of these indicators using Extreme Gradient Boosting(XGBoost),SHapley Additive ex Planations(SHAP),and Partial Least Squares Structural Equation Modeling(PLS-SEM).The results revealed that from 2000 to 2020,both NPP(2.69 g C/(m^(2)·a);P<0.010) and WUE(0.004 g C/(kg H_(2)O·a);P<0.010) increased significantly,while CUE exhibited a non-significant decline(–5.40×10^(–4)/a;P>0.050) across different climatic zones(arid,semi-arid,humid,and sub-humid) and vegetation types(cropland,forest,grassland,shrubland,and wetland).The correlation between WUE and NPP(correlation coefficient of 0.70) was stronger than that between CUE and NPP(correlation coefficient of 0.15).NPP and WUE were primarily influenced by leaf area index,whereas CUE was most strongly affected by elevation.The relationships between the key drivers and the three indicators were largely nonlinear,with stronger driver contributions corresponding to more pronounced nonlinear interactions.Moreover,these nonlinear relationships were modulated by differences in dry versus wet climatic conditions.Geographical factors(e.g.,longitude,latitude,and elevation) further shaped vegetation characteristics(e.g.,fractional vegetation cover and leaf area index) by regulating climatic variables such as temperature,precipitation,and evapotranspiration,ultimately influencing NPP,WUE,and CUE.This study advances the understanding of vegetation carbon–water coupling and provides a scientific basis for ecosystem management and sustainable development policy-making in various climatic zones.
基金supported by the National Key Research and Development Program of China(2023YFD1900300 and 2017YFD0200205)the Agricultural Key-scientific and Core-technological Project of Shaanxi Province,China(2024NYGG011)。
文摘The continuous supply of phosphorus(P)is indispensable in crop production.However,P resources are non-renewable,and environmental concerns like eutrophication associated with its loss from agroecosystems make the sustainable management of P resources essential for ensuring global food security.This study was designed to reduce mineral P inputs through management practices.A field experiment comprising a wheat-maize rotation system was conducted in the Guanzhong Plain of Shaanxi Province,China from 2018-2023.The eight treatments included CK(without P),FP(conventional P application);RP(recommended P);RP80(20% reduction in RP);SRP80(20% reduction in RP with straw wrapping);ARP80(20% reduction in RP with ammonium sulfate instead of urea);SARP80(20% reduction in RP with straw wrapping and ammonium sulfate instead of urea);and SARP60(40% reduction in RP with straw wrapping and ammonium sulfate instead of urea).Crop yield,P uptake,and P fertilizer use efficiency were measured during harvest and throughout the entire period of the study.At the end of the experiment,P fractions were estimated using the Tiessen-Moir P classification method.The results revealed that the grain yields of all the treatments except for RP80 were significantly increased compared to CK,with increases of 14.9-28.8%.Furthermore,agronomic efficiency,apparent P use efficiency,P recovery rate,and partial factor productivity were significantly improved for the treatments that received 20% less P with straw wrapping.Moreover,the enhancement measures significantly increased labile and moderately labile P in the soil.Therefore,straw wrapping with ammonium sulfate instead of urea is one of the most effective ways to reduce mineral P inputs while increasing the efficiency of P in wheat-maize rotation systems.
基金supported by the Institution of Eminence,University of Delhi,grant number[IoE/2023-24/12/FRP].
文摘This research offers valuable insights into the relationship between land use and daytime climatic comfort in high-rise urban developments in Delhi.This city is navigating rapid urbanisation and facing critical environmental challenges like pollution,heat stress,land degradation etc.The study aims to enhance understanding of how diverse land use patterns influence thermal comfort by utilising satellite data from the Landsat/Resourcesat series for classification and MODIS for land surface temperature(LST)extraction.The findings highlight that regions with dense construction and limited green and blue spaces tend to experience lower levels of climatic comfort,with 17.17 Percent of Delhi’s geographical area feeling the adverse effects of the Urban Heat Island(UHI)phenomenon.On a positive note,40.20 Percent of the area is associated with high climatic comfort,primarily due to natural features such as vegetation and water bodies.Furthermore,the research indicates a noteworthy increase in land surface temperatures(LST)from 2000 to 2022,with peak recorded temperatures rising from 38.35℃ in 2000 to 47.27℃ in 2022.In summary,this study emphasises the importance of understanding and addressing the UHI effect in urban settings,providing constructive recommendations for policymakers and stakeholders dedicated to fostering improved livability and sustainability in urban environments.
基金supported by the Gaoligong Mountain Ecological Function Enhancement and Sustainable Development Technology Research(202303AC1000120303)Gaoligong Mountain Ecological Function Enhancement and Invasive Plant Species Prevention and Control Technology Project(2022YFF130240304)National Key R&D Program of China(2022YFC2602500)。
文摘Reconciling biodiversity conservation with economic advancement represents a defining challenge of the Anthropocene epoch.Although ecotourism is widely promoted as a strategy capable of delivering both environmental and developmental benefits,empirical evidence regarding its ecological and socioeconomic impacts remains limited.This study critically examined the Hide-in-Bird Pond(HIBP)model,a rapidly expanding,community-based avitourism framework in China that integrates targeted wildlife provisioning with concealed infrastructure for bird observation,simultaneously establishing a novel income source for economically marginalized rural regions through ecotourism.Semi-structured online interviews were conducted with 98 HIBP operators,and thematic analysis was applied to evaluate current developmental patterns,spatial distribution,and conservation outcomes.A total of 251 HIBP sites were identified across China,predominantly located in biodiversity-rich but economically marginalized regions.These sites collectively supported 524 bird species—36%of China's avifauna—including 148 species classified as nationally protected or threatened(38%of nationally listed bird taxa).These findings suggest that HIBP can serve as an integrative socio-ecological platform that aligns conservation objectives with sustainable rural development.However,the absence of standardized governance frameworks and ecological safeguards poses significant risks to biodiversity an d long-term sustainability.Implementation of science-based adaptive management systems,incorporating systematic biodiversity monitoring,inclusive stakeholder coordination,and certified sustainable tourism protocols,is critical to ensure ecological integrity and sectoral resilience.These findings offer novel insights into aligning conservation objectives with economic development across regions characterized by high biodiversity and persistent economic disadvantage.
基金supported by the National Key Research and Development Program of China(Nos.2022YFF0801104 and 2021YFD1700600)the National Natural Science Foundation of China(No.51809177)the Science Foundation of Nanjing Institute of Geography and Limnology,Chinese Academy of Sciences(No.NIGLAS2022GS08).
文摘Estuarine and bay ecosystems serve as crucial transitional zones for land-based pollutants entering the ocean.However,there is a critical gap in understanding the behavior of emerging pollutants in the numerous small estuaries and bays located in undeveloped coastal areas.This study provides insights into the fate of antibiotics in these small and scattered estuaries and bays in Shantou's coast,driven by land use types and hydrodynamic conditions.The findings indicated that estuaries were more heavily polluted with antibiotics than the bays(P<0.05),with tetracyclines and fluoroquinolones as the primary antibiotics.Antibiotic pollution levels were more severe in October than in June(P<0.01).Rainfall runoff,aquaculture tailwater,and river discharge were identified as the main sources of antibiotic pollution.Build-up land and aquaculture ponds were the primary land use types contributing to antibiotic pollution.The total antibiotic concentrations in June were positively correlated with the proportion of aquaculture ponds(P<0.05)and negatively correlated with the proportions of cropland and grassland(P<0.05).The concentrations of lomefloxacin and ofloxacin were positively correlated with build-up land.The antibiotic concentrations exhibited strong spatial heterogeneity within both bay and estuarine ecosystems driven by different hydrodynamic conditions.A comparative analysis of global estuaries and bays revealed that specific land-use types and hydrodynamic conditions produced similar trends in antibiotic fate.These insights offered new perspectives to safeguard the health of estuarine and bay ecosystems,such as altering landscape patterns and regulating aquaculture activities.
基金Financial support provided by CUHP to DB in the form of a Ph.D.fellowship is also acknowledged.
文摘Arisaema propinquum(A.propinquum)is a medicinal tuberous plant native to the Himalayan region,belonging to the family Araceae.It has a unique appearance due to its inflorescence,which is strikingly elegant and resembles that of Arisaema triphyllum,also known as“Jack-in-the-pulpit”.This review provides a comprehensive overview of A.propinquum,covering its taxonomy,geographic distribution,and traditional uses.While ethnobotanical information on A.propinquum is relatively well documented,species-specific pharmacological,mechanistic,and in vivo studies remain limited.Accordingly,evidence from related Arisaema species is discussed cautiously as contextual support for phytochemical similarity rather than as direct proof of bioactivity in A.propinquum.This study seeks to establish a relationship between ethnopharmacological use and scientific enquiries into A.propinquum,including a comparison of the various species of the family Araceae and their recent contributions to traditional medicinal advancements.The review mainly emphasises the traditional uses,phytochemistry,safety and toxicity data,and future techniques for its conservation,with increased yield and impact.It highlights A.propinquum as an underexplored yet promising candidate for focused phytochemical characterisation,experimental validation of traditional claims,and conservation-oriented research.Overall,the available evidence indicates that while direct experimental data on the plant remain limited,its placement within a genus rich in bioactive secondary metabolites makes it a strong candidate for focused,species-specific future research.
基金supported by the National Natural Science Foundation of China(T2350008)the STI2030-Major Projects[2021ZD0203000(2021ZD0203003)]the Open Research Fund of the State Key Laboratory of Brain-Machine Intelligence,Zhejiang University(BMI2400014).
文摘Addiction,a complex and chronic neurobiological disorder,is characterized by compulsive substance use despite harmful consequences,leading to persistent alterations in brain function,particularly within the reward,motivation,and decision-making systems.Despite the availability of a range of treatment options,including pharmacotherapy and behavioral therapies,relapse remains a major challenge,with many individuals struggling to maintain long-term recovery.Current treatments often show limited efficacy,underscoring the need for novel therapeutic strategies that can address the underlying neurobiological disruptions in addiction.
