在经济全球化和"走出去"的大背景下,企业国际化已成为企业增强国际竞争力、获取更大经济效益的手段之一。与此同时,学术界对企业国际化也越来越关注。基于Web of Science核心合集数据库收录的2008—2020年企业国际化的文献数...在经济全球化和"走出去"的大背景下,企业国际化已成为企业增强国际竞争力、获取更大经济效益的手段之一。与此同时,学术界对企业国际化也越来越关注。基于Web of Science核心合集数据库收录的2008—2020年企业国际化的文献数据为样本,运用CiteSpace分析该领域的研究现状、研究热点、研究前沿等。研究发现:企业国际化研究的发文量呈波动上升的趋势,美国、英国、西班牙在该领域研究中较为活跃;企业国际化的高频关键词涉及企业国际化的理论基础研究、企业国际化能力评价研究和企业国际化动力机制研究;社会情感财富、制度距离、乌普萨拉模型等是进一步研究的前沿方向。展开更多
目的介绍乌普萨拉监测中心(UMC)信号检测方法vigiRank的原理、流程和应用,为完善我国药物警戒信号检测提供参考。方法检索Scopus、Web of Science、PubMed等数据库进行文献调研,并查阅UMC官网,分析vigiRank预测模型的工作流程及应用。结...目的介绍乌普萨拉监测中心(UMC)信号检测方法vigiRank的原理、流程和应用,为完善我国药物警戒信号检测提供参考。方法检索Scopus、Web of Science、PubMed等数据库进行文献调研,并查阅UMC官网,分析vigiRank预测模型的工作流程及应用。结果UMC开发的信号检测方法vigiRank,结合了药品不良反应(ADR)报告的多个证据强度,包括信息报告(INF)、叙述(NAR)、去激发试验(DCH)、再激发试验(RCH)、因果关系评估(CAU和CAU+)、发病时间(TTO)、单独报告(SOL)、多个报告元素(MUL)、近期报告(REC)、比例失衡报告(DIS)、地理分布(GEO)、时间趋势(TRE),通过lasso-logistic模型确定5个变量纳入到vigiRank评分体系,计算出药品-不良反应(drug-ADR)对的vigiRank分数,由专家团队按照分数的降序排列进行初步评估,筛选出需要考量的drug-ADR对,再深入评估并最终决定出风险信号。结论vigiRank预测模型兼顾ADR报告的数量和质量,以科学的方式识别药物危害的早期信号,对完善我国ADR信号检测方法具有较大的参考价值。展开更多
Anders Wikström was born in 1937.He studied at Uppsala University,in Sweden,graduating in Mathematics,Chemistry and Geology in 1961 and obtaining his Doctoral degree in 1968 in Mineralogy and Petrology with a the...Anders Wikström was born in 1937.He studied at Uppsala University,in Sweden,graduating in Mathematics,Chemistry and Geology in 1961 and obtaining his Doctoral degree in 1968 in Mineralogy and Petrology with a thesis dealing with retrograde reactions in eclogites.Between 1968 and 2000,when he retired,Anders was employed as state geologist and then senior state geologist at the Geological Survey of Sweden.He was very active in the study of granites and metamorphic rocks from Sweden.In 2012 he contacted the IUGS Heritage Stone Task Group with the purpose of bringing greater attention to historically important natural stones that had been used in construction for centuries in from Sweden,notably Kolmården stone and Swedish porphyries.Published information on these was largely in Swedish so he authored two papers on this subject in English to bring these to the attention of the wider scientific community and general public.展开更多
文摘在经济全球化和"走出去"的大背景下,企业国际化已成为企业增强国际竞争力、获取更大经济效益的手段之一。与此同时,学术界对企业国际化也越来越关注。基于Web of Science核心合集数据库收录的2008—2020年企业国际化的文献数据为样本,运用CiteSpace分析该领域的研究现状、研究热点、研究前沿等。研究发现:企业国际化研究的发文量呈波动上升的趋势,美国、英国、西班牙在该领域研究中较为活跃;企业国际化的高频关键词涉及企业国际化的理论基础研究、企业国际化能力评价研究和企业国际化动力机制研究;社会情感财富、制度距离、乌普萨拉模型等是进一步研究的前沿方向。
文摘目的介绍乌普萨拉监测中心(UMC)信号检测方法vigiRank的原理、流程和应用,为完善我国药物警戒信号检测提供参考。方法检索Scopus、Web of Science、PubMed等数据库进行文献调研,并查阅UMC官网,分析vigiRank预测模型的工作流程及应用。结果UMC开发的信号检测方法vigiRank,结合了药品不良反应(ADR)报告的多个证据强度,包括信息报告(INF)、叙述(NAR)、去激发试验(DCH)、再激发试验(RCH)、因果关系评估(CAU和CAU+)、发病时间(TTO)、单独报告(SOL)、多个报告元素(MUL)、近期报告(REC)、比例失衡报告(DIS)、地理分布(GEO)、时间趋势(TRE),通过lasso-logistic模型确定5个变量纳入到vigiRank评分体系,计算出药品-不良反应(drug-ADR)对的vigiRank分数,由专家团队按照分数的降序排列进行初步评估,筛选出需要考量的drug-ADR对,再深入评估并最终决定出风险信号。结论vigiRank预测模型兼顾ADR报告的数量和质量,以科学的方式识别药物危害的早期信号,对完善我国ADR信号检测方法具有较大的参考价值。
文摘Anders Wikström was born in 1937.He studied at Uppsala University,in Sweden,graduating in Mathematics,Chemistry and Geology in 1961 and obtaining his Doctoral degree in 1968 in Mineralogy and Petrology with a thesis dealing with retrograde reactions in eclogites.Between 1968 and 2000,when he retired,Anders was employed as state geologist and then senior state geologist at the Geological Survey of Sweden.He was very active in the study of granites and metamorphic rocks from Sweden.In 2012 he contacted the IUGS Heritage Stone Task Group with the purpose of bringing greater attention to historically important natural stones that had been used in construction for centuries in from Sweden,notably Kolmården stone and Swedish porphyries.Published information on these was largely in Swedish so he authored two papers on this subject in English to bring these to the attention of the wider scientific community and general public.
