Since the discovery of penicillin in 1928,antibiotics have revolutionized modern medicine by effectively treating infectious diseases and saving countless lives.However,the widespread development of antimicrobial resi...Since the discovery of penicillin in 1928,antibiotics have revolutionized modern medicine by effectively treating infectious diseases and saving countless lives.However,the widespread development of antimicrobial resistance(AMR)now threatens the efficacy and longevity of these critical drugs.A study published in The Lancet reported that bacterial AMR contributed to approximately 4.95 million deaths globally in 2019,with 1.27 million directly attributable to AMR(Fig.1)[1].Natural products(NPs)continue to play a crucial role in discovering new antibiotics.展开更多
文摘Since the discovery of penicillin in 1928,antibiotics have revolutionized modern medicine by effectively treating infectious diseases and saving countless lives.However,the widespread development of antimicrobial resistance(AMR)now threatens the efficacy and longevity of these critical drugs.A study published in The Lancet reported that bacterial AMR contributed to approximately 4.95 million deaths globally in 2019,with 1.27 million directly attributable to AMR(Fig.1)[1].Natural products(NPs)continue to play a crucial role in discovering new antibiotics.
