Because of the widespread existence of unsymmetrical system in the production process, its research is getting more and more attention. In this paper, a regression optimal functional control method is proposed for a c...Because of the widespread existence of unsymmetrical system in the production process, its research is getting more and more attention. In this paper, a regression optimal functional control method is proposed for a class of unsymmetrical system. For the positive-negative model of the unsymmetrical system, a regression optimal functional controller is designed, which can make the system stable. The proposed algorithm has less computation and good control effect. Finally, three simulation examples are given to verify the effectiveness of the proposed algorithm.展开更多
Reduction of diaryldiselenides by the system of Cp2TiCl2/Bu'MgBr/THF gave the nucleophilic arylselenium complex. They reacted with diaryl iodonium salts to afford unsymmetrical diaryl selenides in high yields.
This paper presents the instability analysis of unsymmetrical rotor bearing system in accordance with the Campbell diagrams of the system, and concludes that the unstable regions stay in high speed regions with the in...This paper presents the instability analysis of unsymmetrical rotor bearing system in accordance with the Campbell diagrams of the system, and concludes that the unstable regions stay in high speed regions with the increase of supporting stiffness and they decrease or disappear with the decrease of the inequality diametrical moments of the inertia and stiffness of shaft.展开更多
Regular valveless piezoelectric pumps have rectifying elements outside their chambers to produce net flow. These rectifying elements outside the chamber will increase the overall volume of the pump and prevent its min...Regular valveless piezoelectric pumps have rectifying elements outside their chambers to produce net flow. These rectifying elements outside the chamber will increase the overall volume of the pump and prevent its minimization. Valveless piezoelectric pump with unsymmetrical slopes elements（USE）, proposed in this paper, differs from other valveless pumps in that it is easy to be minimized by developing the chamber bottom as such a rectifying element. In this research, the working principle of the proposed pump was analyzed first. Numerical models were thereby established and numerical simulation was conducted to the chamber flow field with the method of time-dependent velocity. The effects of the USEs on the flow field in the chamber were shown clearly in simulation. And the particular feature of flow field in the chamber was discovered. It behaves a complex flow field, in which strong turbulent occurs companying a lot of vortexes in different directions and different sizes. This feature is just opposite to what regular piezoelectric pumps expect： a moderate flow field. The turbulent flow could be used to have different liquids stirred and well mixed in the chamber to produce homogeneous solution, emulsion or turbid liquid. Meanwhile, numerical simulation also presents the effect of the angles difference of the two slopes upon the flow field, and upon the flow rate of the pump, which fits to the theoretical analysis. Experiments with the proposed pump were also conducted to verify the numerical results. In these experiments, six USEs with different slope angles were used for efficiency tests, which proved the validity and reliability of the numerical analysis. The data obtained from numerical analysis agree well with that from the experiments. The errors ranged from 4.4% to 14.8% with their weighted average error being 9.7%.展开更多
Typically,liquid pump and liquids mixer are two separate devices.The invention of piezoelectric pump makes it possible to integrate the two devices.Hower,the existing piezoelectric mixing-pumps are larger because the ...Typically,liquid pump and liquids mixer are two separate devices.The invention of piezoelectric pump makes it possible to integrate the two devices.Hower,the existing piezoelectric mixing-pumps are larger because the need the space outside the chamber,and another shortcome of them is that they cannot adjust the mixing ratio of two liquids.In this paper,a new piezoelectric pump being capable of integrating mixer and pump is presented,based on the theory of the piezoelectric pump with the unsymmetrical slopes element（USE）.Besides the features of two inlets and one outlet,the piezoelectric pump has a rotatable unsymmetrical slopes element（RUSE）.When the pump works,two fluids flow into the inlet channels respectively.Then the RUSE controls the ratio of the two flows by adjusting the flow resistances of the two inlet channels.The fluids form a net flow due to the USE principle,while they are mixed into a homogeneous solution due to strong turbulence flow field and complex vortices generated by RUSE in the chamber.And then the solution flows through the outlet.Firstly,the theoretical analysis on this pump is performed.Meanwhile,the flow field in the chamber is calculated and simulated.And then,the relationship between the flows of the two channels and the rotating angle of the RUSE is set up and analyzed.Finally,experiment with the proposed pump is carried out to verify the numerical results.A RUSE with 20° slope angle is used in the experiment.Four sets of data are tested with the RUSE at the rotating angles of 0°,6°,11°,and 16°,respectively,corresponding to the numerical models.The experimental results show that the empirical data and the theoretical data share the same trend.The maximum error between the theoretical flow and the experimental flow is 11.14%,and the maximum error between the theoretical flow ratio of the two inlets and the experimental one is 2.5%.The experiment verified the theoretical analysis.The proposed research provides a new idea for integration of micro liquids mixer and micro liquids pump.展开更多
According to the interaction of three shallow tunnels with large section, the analytical solution to rock pressure has been derived and discussed. The load model is given when the bilateral tunnels are excavated. Acco...According to the interaction of three shallow tunnels with large section, the analytical solution to rock pressure has been derived and discussed. The load model is given when the bilateral tunnels are excavated. According to the model, the stresses of three tunnels and single tunnel are calculated and compared to analyze the distribution characteristics, where the stresses are influenced by controlling factors of clear distance, covering depth and inclination angle of ground surface. The results show that, in general, the bias distribution is more serious. Therefore, it is significant to settle down the load model of three shallow tunnels so as to determine the measure of reinforcement and design the structure of support. The model and results can be used as a theoretical basis in designation and further research of the three shallow tunnels.展开更多
By combining the results of laboratory model tests with relevant flow rules, the failure mode of shallow unsymmetrical loading tunnels and the corresponding velocity field were established. According to the principle ...By combining the results of laboratory model tests with relevant flow rules, the failure mode of shallow unsymmetrical loading tunnels and the corresponding velocity field were established. According to the principle of virtual power, the upper bound solution for surrounding rock pressure of shallow unsymmetrical loading tunnel was derived and verified by an example. The results indicate that the calculated results of the derived upper bound method for surrounding rock pressure of shallow unsymmetrical loading tunnels are relatively close to those of the existing "code method" and test results, which means that the proposed method is feasible. The current code method underestimates the unsymmetrical loading feature of surrounding rock pressure of shallow unsymmetrical loading tunnels, so it is unsafe; when the burial depth is less or greater than two times of the tunnel span and the unsymmetrical loading angle is less than 45°, the upper bound method or the average value of the results calculated by the upper bound method and code method respectively, is comparatively reasonable. When the burial depth is greater than two times of the tunnel span and the unsymmetrical loading angle is greater than 45°, the code method is more suitable.展开更多
A facile,rapid and efficient method for the synthesis of molecular tweezers containing chiral unsymmetrical urea unit in solvent- free conditions using microwave was reported.
The application of multi-hull ship or trimaran vessel as a mode of transports in both river and sea environments have grown rapidly in recent years.Trimaran vessels are currently of interest for many new high speed sh...The application of multi-hull ship or trimaran vessel as a mode of transports in both river and sea environments have grown rapidly in recent years.Trimaran vessels are currently of interest for many new high speed ship projects due to the high levels of hydrodynamic efficiency that can be achieved,compared to the mono-hull and catamaran hull forms.The purpose of this study is to identify the possible effects of using an unsymmetrical trimaran ship model with configuration（S/L） 0.1-0.3 and R/L=0.1-0.2.Unsymmetrical trimaran ship model with main dimensions： L=2000mm,B=200 mm and T=45 mm.Experimental methods（towing tank） were performed in the study using speed variations at Froude number 0.1-0.6.The ship model was pulled by an electric motor whose speed could be varied and adjusted.The ship model resistance was measured precisely by using a load cell transducer.The comparison of ship resistance for each configuration with mono-hull was shown on the graph as a function of the total resistance coefficient and Froude number.The test results found that the effective drag reduction could be achieved up to 17% at Fr=0.35 with configuration S/L=0.1.展开更多
A new shadow mask plasma display panel （SMPDP） is presented in this article. The unsymmetrical geometry structure of the discharge cell is its main feature. A macro-cell with a ratio of 40：1 was designed and fabric...A new shadow mask plasma display panel （SMPDP） is presented in this article. The unsymmetrical geometry structure of the discharge cell is its main feature. A macro-cell with a ratio of 40：1 was designed and fabricated. The geometrical parameters and electrode＇s structure of the discharge cell of the unsymmetrical SMPDP were optimized. Compared with current SMPDP, its luminous efficiency was obviously improved. Then a 32-inch wide video graphics array （WVGA） unsymmetrical SMPDP with a luminous efficacy of 1.8 Lm/W was produced.展开更多
A new practical method for the synthesis of unsymmetrical ureas was achieved by reaction of phenylurea with primary and secondary amines under neutral and mild condition in very good yields. The reaction took place in...A new practical method for the synthesis of unsymmetrical ureas was achieved by reaction of phenylurea with primary and secondary amines under neutral and mild condition in very good yields. The reaction took place in refluxing dioxane and does not require any catalyst or additives.展开更多
Unsymmetrical bisacridines(UAs) are a novel potent class of antitumor-active therapeutics.A significant route of phase II drug metabolism is conjugation with glutathione(GSH),which can be non-enzymatic and/or catalyze...Unsymmetrical bisacridines(UAs) are a novel potent class of antitumor-active therapeutics.A significant route of phase II drug metabolism is conjugation with glutathione(GSH),which can be non-enzymatic and/or catalyzed by GSH-dependent enzymes.The aim of this work was to investigate the GSHmediated metabolic pathway of a representative UA,C-2028.GSH-supplemented incubations of C-2028 with rat,but not with human,liver cytosol led to the formation of a single GSH-related metabolite.Interestingly,it was also revealed with rat liver microsomes.Its formation was NADPH-independent and was not inhibited by co-incubation with the cytochrome P450(CYP450) inhibitor 1-aminobenzotriazole.Therefore,the direct conjugation pathway occurred without the prior CYP450-catalyzed bioactivation of the substrate.In turn,incubations of C-2028 and GSH with human recombinant glutathione S-transferase(GST) P1-1 or with heat-/ethacrynic acid-inactivated liver cytosolic enzymes resulted in the presence or lack of GSH conjugated form,respectively.These findings proved the necessary participation of GST in the initial activation of the GSH thiol group to enable a nucleophilic attack on the substrate molecule.Another C-2028-GSH S-conjugate was also formed during non-enzymatic reaction.Both GSH S-conjugates were characterized by combined liquid chromatography/tandem mass spectrometry.Mechanisms for their formation were proposed.The ability of C-2028 to GST-mediated and/or direct GSH conjugation is suspected to be clinically important.This may affect the patient’s drug clearance due to GST activity,loss of GSH,or the interactions with GSH-conjugated drugs.Moreover,GST-mediated depletion of cellular GSH may increase tumor cell exposure to reactive products of UA metabolic transformations.展开更多
A new unsymmetrical Schiff base ligand (H2LLi) was synthesized using L-lysine, salicylaldehyde and 2-hydroxy-1-naphthaldehyde. Three solid metal complexes of this ligand \[Ln(H2L)(NO3)\] NO3·2H2O (Ln=La, Sm, Ho) ...A new unsymmetrical Schiff base ligand (H2LLi) was synthesized using L-lysine, salicylaldehyde and 2-hydroxy-1-naphthaldehyde. Three solid metal complexes of this ligand \[Ln(H2L)(NO3)\] NO3·2H2O (Ln=La, Sm, Ho) have been prepared and characterized by elemental analyses, IR spectra, UV spectra, TG-DTG and molar conductance. The antibacterial activities of the ligand and its complexes are also studied. The antibacterial experiments indicate that the ligand and its complexes possess antibacterial activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis and that the complexes have higher activity than those of the ligand.展开更多
In order to study the unsymmetrical load effect in geological bedding strata for the Muzhailing tunnel on the Lanzhou-Chongqing passenger dedicated line in China, we investigated the deformation, mechanical response a...In order to study the unsymmetrical load effect in geological bedding strata for the Muzhailing tunnel on the Lanzhou-Chongqing passenger dedicated line in China, we investigated the deformation, mechanical response and pressure of the surrounding rock and the mechanical characteristics of bolts of the tunnel. The results suggest that open zones appear at arch and invert where joints open up, when layered stratum is horizontal, or when the dip angle of in- clined bedding is small. Open zones occur perpendicular to a joint. The failure mode is bending disjunction at the arch tain shear displacement, and lead to obvious geological bedding unsymmetrical load. The failure mode is shear damage. For the joint dip angle in the range of 75-90°, the failure mode is flexural crushing at the wall and vertical shear rup- ture above the arch. The restraining effect of two sides weakens for vertical dip. On the whole, shear failure instabilitytrend would occur and the tunnel collapses evenly. When the angle between the bolt and structure plane is greater than 23°, bolts can enhance the shearing stiffness of joint plane. Unfortunately, in the general purpose graph of tunnel for 250 km/h of passenger dedicated lines, the bolts have equal length and spacing. The rationale behind this is worthy offurther study. For inclined bedding, the surrounding rock pressure at the left wall is more than that at the right wall. In addition, lining is likely to be damaged at left shoulder and side wall. With the dip angle increasing, the unsymmetrical load gradually achieves symmetry. Asymmetry design for support is recommended to reduce the unsymmetrical load on lining disturbed by excavation.展开更多
A novel thiazolothiazole-bridged imidazole derivative(1) was found to exhibit blue fluorescence in gaseous state or in methanol and yellow fluorescence in solid state. The N-alkylation of imidazole subunit(s) in 1 usi...A novel thiazolothiazole-bridged imidazole derivative(1) was found to exhibit blue fluorescence in gaseous state or in methanol and yellow fluorescence in solid state. The N-alkylation of imidazole subunit(s) in 1 using n-propyl iodide generated unsymmetrically or symmetrically alkylated thiazolothiazolebridged imidazolium salts with good water solubility and remarkably strong emission in solution. Furthermore, the replacement of iodide counter-anion by triflate or bis(trifluoromethane sulfonyl)imide achieved remarkably strong emission in solid state and in solution as well as good water solubility. The strong fluorescence of dicationic salts with triflate and NTf_(2)^(-)counter-anions in solid state can be ascribed to their twisted and rigid structures induced by interionic C-H···F hydrogen bonding.展开更多
A new unsymmetrical solid Schiff base (LLi) was synthesized using L-lysine, o-vanillin and 2-hydroxy-l-naphthaldehyde. Solid La(Ⅲ) complex of this ligand [LaL(NO3)](NO3)·2H2O was prepared and characterized by el...A new unsymmetrical solid Schiff base (LLi) was synthesized using L-lysine, o-vanillin and 2-hydroxy-l-naphthaldehyde. Solid La(Ⅲ) complex of this ligand [LaL(NO3)](NO3)·2H2O was prepared and characterized by elemental analyses, IR, UV and molar conductance. The thermal decomposition kinetics of the complex for the second stage were studied under non-isothermal condition by TG and DTG methods. The kinetic equation may be expressed as: dα/dt=A·e-E/RT·(1-α)2. The kinetic parameters(E, A), activation entropy S≠ and activation free-energy G≠ were also gained.展开更多
A new unsymmetrical Schiff base ligand (H_2LLi) was synthesized using L-lysine, o-vanillin and salicylaladyde. Three solid metal complexes of this ligand [Ln(H_2L)(NO_3)] NO_3·2H_2O (Ln=Sm, Ho, Tm) were prepared ...A new unsymmetrical Schiff base ligand (H_2LLi) was synthesized using L-lysine, o-vanillin and salicylaladyde. Three solid metal complexes of this ligand [Ln(H_2L)(NO_3)] NO_3·2H_2O (Ln=Sm, Ho, Tm) were prepared and characterized by elemental analyses, IR spectra, UV spectra, TG-DTG and molar conductance. The ligand synthesized are chelating agent. The nitrogen atoms of Schiff base, oxygen atoms of hydroxybenzene, methoxide and carboxyl are all coordinated to the metal ions. Carboxyl and the nitrate ion within the coordination sphere are coordinated to the metal ion in a mondentate or bidentate fashion. Water molecules are lied in crystal substances. The antibacterial activity of the ligand and its complexes was also studied. The antibacterial experiments indicate that they have antibacterial activity to E. coli, S. aureus, B. subtilis and the complexes have higher activity than the ligand.展开更多
An unsymmetrical quantum key distribution protocol is proposed, in which Greenherger-Horne-Zeilinger （GHZ） triplet states are used to obtain the secret key. Except the lost qubits due to the unperfectness of the phy...An unsymmetrical quantum key distribution protocol is proposed, in which Greenherger-Horne-Zeilinger （GHZ） triplet states are used to obtain the secret key. Except the lost qubits due to the unperfectness of the physical devices, the unsymmetrical characteristic makes all transmitted qubits useful. This leads to：an excellent efficiency, which reaches 100% in an ideal case. The ＇security is studied from the aspect of information theory. By using the correlation of the GHZ tripartite entanglement state, eavesdropping can be easily checked out, which indicates that the presented protocol is more secure.展开更多
The 1/2 subharmonic resonance of a shaft with unsymmetrical stiffness is studied. By means of the Hamilton's principle the nonlinear differential equations of motion of the rotating shaft are derived in the rotati...The 1/2 subharmonic resonance of a shaft with unsymmetrical stiffness is studied. By means of the Hamilton's principle the nonlinear differential equations of motion of the rotating shaft are derived in the rotating rectangular coordinate system. Transforming the equations of motion from rotating coordinate system into stationary coordinate system and introducing a complex variable, the equation of motion in complex variable form is obtained, in which the stiffness coefficient varies periodically with time. It presents a nonlinear oscillation system under parametric excitation. By applying the method of multiple scales (MMS) the averaged equation, the bifurcating response equations and local bifurcating set are obtained. Via the theory of singularity, the stability of constant solutions is analyzed and bifurcating response curves are obtained. This study shows that the rotating shaft has rich bifurcation phenomena.展开更多
Tetrabutylammonium fluoride （TBAF） effectively facilitated a denitrative substitution reaction of electron-deficient nitroarenes with phenylthiotrimethylsilane （PhSTMS） under mild and base-free neutral conditions ...Tetrabutylammonium fluoride （TBAF） effectively facilitated a denitrative substitution reaction of electron-deficient nitroarenes with phenylthiotrimethylsilane （PhSTMS） under mild and base-free neutral conditions at room temperature, providing a practical and efficient synthesis of useful unsymmetrical diaryl thioethers. Nitroarenes bearing ortho- and para-positioned electron-withdrawing groups are the most reactive substrates, indicating that this reaction most possibly proceeded via the nucleophilic aromatic substitution （SNAr） mechanism.展开更多
文摘Because of the widespread existence of unsymmetrical system in the production process, its research is getting more and more attention. In this paper, a regression optimal functional control method is proposed for a class of unsymmetrical system. For the positive-negative model of the unsymmetrical system, a regression optimal functional controller is designed, which can make the system stable. The proposed algorithm has less computation and good control effect. Finally, three simulation examples are given to verify the effectiveness of the proposed algorithm.
文摘Reduction of diaryldiselenides by the system of Cp2TiCl2/Bu'MgBr/THF gave the nucleophilic arylselenium complex. They reacted with diaryl iodonium salts to afford unsymmetrical diaryl selenides in high yields.
文摘This paper presents the instability analysis of unsymmetrical rotor bearing system in accordance with the Campbell diagrams of the system, and concludes that the unstable regions stay in high speed regions with the increase of supporting stiffness and they decrease or disappear with the decrease of the inequality diametrical moments of the inertia and stiffness of shaft.
基金supported by National Natural Science Foundation of China (Grant No. 50575007, Grant No. 50775109)
文摘Regular valveless piezoelectric pumps have rectifying elements outside their chambers to produce net flow. These rectifying elements outside the chamber will increase the overall volume of the pump and prevent its minimization. Valveless piezoelectric pump with unsymmetrical slopes elements（USE）, proposed in this paper, differs from other valveless pumps in that it is easy to be minimized by developing the chamber bottom as such a rectifying element. In this research, the working principle of the proposed pump was analyzed first. Numerical models were thereby established and numerical simulation was conducted to the chamber flow field with the method of time-dependent velocity. The effects of the USEs on the flow field in the chamber were shown clearly in simulation. And the particular feature of flow field in the chamber was discovered. It behaves a complex flow field, in which strong turbulent occurs companying a lot of vortexes in different directions and different sizes. This feature is just opposite to what regular piezoelectric pumps expect： a moderate flow field. The turbulent flow could be used to have different liquids stirred and well mixed in the chamber to produce homogeneous solution, emulsion or turbid liquid. Meanwhile, numerical simulation also presents the effect of the angles difference of the two slopes upon the flow field, and upon the flow rate of the pump, which fits to the theoretical analysis. Experiments with the proposed pump were also conducted to verify the numerical results. In these experiments, six USEs with different slope angles were used for efficiency tests, which proved the validity and reliability of the numerical analysis. The data obtained from numerical analysis agree well with that from the experiments. The errors ranged from 4.4% to 14.8% with their weighted average error being 9.7%.
基金supported by National Natural Science Foundation of China (Grant No. 50735002, Grant No. 50775109, and Grant No. 51075201)
文摘Typically,liquid pump and liquids mixer are two separate devices.The invention of piezoelectric pump makes it possible to integrate the two devices.Hower,the existing piezoelectric mixing-pumps are larger because the need the space outside the chamber,and another shortcome of them is that they cannot adjust the mixing ratio of two liquids.In this paper,a new piezoelectric pump being capable of integrating mixer and pump is presented,based on the theory of the piezoelectric pump with the unsymmetrical slopes element（USE）.Besides the features of two inlets and one outlet,the piezoelectric pump has a rotatable unsymmetrical slopes element（RUSE）.When the pump works,two fluids flow into the inlet channels respectively.Then the RUSE controls the ratio of the two flows by adjusting the flow resistances of the two inlet channels.The fluids form a net flow due to the USE principle,while they are mixed into a homogeneous solution due to strong turbulence flow field and complex vortices generated by RUSE in the chamber.And then the solution flows through the outlet.Firstly,the theoretical analysis on this pump is performed.Meanwhile,the flow field in the chamber is calculated and simulated.And then,the relationship between the flows of the two channels and the rotating angle of the RUSE is set up and analyzed.Finally,experiment with the proposed pump is carried out to verify the numerical results.A RUSE with 20° slope angle is used in the experiment.Four sets of data are tested with the RUSE at the rotating angles of 0°,6°,11°,and 16°,respectively,corresponding to the numerical models.The experimental results show that the empirical data and the theoretical data share the same trend.The maximum error between the theoretical flow and the experimental flow is 11.14%,and the maximum error between the theoretical flow ratio of the two inlets and the experimental one is 2.5%.The experiment verified the theoretical analysis.The proposed research provides a new idea for integration of micro liquids mixer and micro liquids pump.
基金Projects(2013CB036004, 2011CB013800) supported by the National Basic Research Program of ChinaProject(51178468, 50908234) supported by the National Natural Science Foundation of ChinaProject(2011G103-B) supported by the Science and Technology Development of Railway in China
文摘According to the interaction of three shallow tunnels with large section, the analytical solution to rock pressure has been derived and discussed. The load model is given when the bilateral tunnels are excavated. According to the model, the stresses of three tunnels and single tunnel are calculated and compared to analyze the distribution characteristics, where the stresses are influenced by controlling factors of clear distance, covering depth and inclination angle of ground surface. The results show that, in general, the bias distribution is more serious. Therefore, it is significant to settle down the load model of three shallow tunnels so as to determine the measure of reinforcement and design the structure of support. The model and results can be used as a theoretical basis in designation and further research of the three shallow tunnels.
基金Project(2014M560652)supported by China Postdoctoral Science FoundationProjects(2011CB013802,2013CB036004)supported by the National Basic Research Program of China
文摘By combining the results of laboratory model tests with relevant flow rules, the failure mode of shallow unsymmetrical loading tunnels and the corresponding velocity field were established. According to the principle of virtual power, the upper bound solution for surrounding rock pressure of shallow unsymmetrical loading tunnel was derived and verified by an example. The results indicate that the calculated results of the derived upper bound method for surrounding rock pressure of shallow unsymmetrical loading tunnels are relatively close to those of the existing "code method" and test results, which means that the proposed method is feasible. The current code method underestimates the unsymmetrical loading feature of surrounding rock pressure of shallow unsymmetrical loading tunnels, so it is unsafe; when the burial depth is less or greater than two times of the tunnel span and the unsymmetrical loading angle is less than 45°, the upper bound method or the average value of the results calculated by the upper bound method and code method respectively, is comparatively reasonable. When the burial depth is greater than two times of the tunnel span and the unsymmetrical loading angle is greater than 45°, the code method is more suitable.
文摘A facile,rapid and efficient method for the synthesis of molecular tweezers containing chiral unsymmetrical urea unit in solvent- free conditions using microwave was reported.
基金supported by the Directorate for Research and Community Service,University of Indonesia(RUUI Utama 2012),Jakarta,Indonesia
文摘The application of multi-hull ship or trimaran vessel as a mode of transports in both river and sea environments have grown rapidly in recent years.Trimaran vessels are currently of interest for many new high speed ship projects due to the high levels of hydrodynamic efficiency that can be achieved,compared to the mono-hull and catamaran hull forms.The purpose of this study is to identify the possible effects of using an unsymmetrical trimaran ship model with configuration（S/L） 0.1-0.3 and R/L=0.1-0.2.Unsymmetrical trimaran ship model with main dimensions： L=2000mm,B=200 mm and T=45 mm.Experimental methods（towing tank） were performed in the study using speed variations at Froude number 0.1-0.6.The ship model was pulled by an electric motor whose speed could be varied and adjusted.The ship model resistance was measured precisely by using a load cell transducer.The comparison of ship resistance for each configuration with mono-hull was shown on the graph as a function of the total resistance coefficient and Froude number.The test results found that the effective drag reduction could be achieved up to 17% at Fr=0.35 with configuration S/L=0.1.
基金the Programme of Introducing Talents of Discipline to Universities,Project of the Ministry of Education of China(No.B07027)National Natural Science Foundation of China(No.60271016)Young Elitist Education and Research Fund of Southeast University(No.4006001007)
文摘A new shadow mask plasma display panel （SMPDP） is presented in this article. The unsymmetrical geometry structure of the discharge cell is its main feature. A macro-cell with a ratio of 40：1 was designed and fabricated. The geometrical parameters and electrode＇s structure of the discharge cell of the unsymmetrical SMPDP were optimized. Compared with current SMPDP, its luminous efficiency was obviously improved. Then a 32-inch wide video graphics array （WVGA） unsymmetrical SMPDP with a luminous efficacy of 1.8 Lm/W was produced.
基金Financial support of this work from the Research Council of the University of Mazandaran is gratefully acknowledged
文摘A new practical method for the synthesis of unsymmetrical ureas was achieved by reaction of phenylurea with primary and secondary amines under neutral and mild condition in very good yields. The reaction took place in refluxing dioxane and does not require any catalyst or additives.
文摘Unsymmetrical bisacridines(UAs) are a novel potent class of antitumor-active therapeutics.A significant route of phase II drug metabolism is conjugation with glutathione(GSH),which can be non-enzymatic and/or catalyzed by GSH-dependent enzymes.The aim of this work was to investigate the GSHmediated metabolic pathway of a representative UA,C-2028.GSH-supplemented incubations of C-2028 with rat,but not with human,liver cytosol led to the formation of a single GSH-related metabolite.Interestingly,it was also revealed with rat liver microsomes.Its formation was NADPH-independent and was not inhibited by co-incubation with the cytochrome P450(CYP450) inhibitor 1-aminobenzotriazole.Therefore,the direct conjugation pathway occurred without the prior CYP450-catalyzed bioactivation of the substrate.In turn,incubations of C-2028 and GSH with human recombinant glutathione S-transferase(GST) P1-1 or with heat-/ethacrynic acid-inactivated liver cytosolic enzymes resulted in the presence or lack of GSH conjugated form,respectively.These findings proved the necessary participation of GST in the initial activation of the GSH thiol group to enable a nucleophilic attack on the substrate molecule.Another C-2028-GSH S-conjugate was also formed during non-enzymatic reaction.Both GSH S-conjugates were characterized by combined liquid chromatography/tandem mass spectrometry.Mechanisms for their formation were proposed.The ability of C-2028 to GST-mediated and/or direct GSH conjugation is suspected to be clinically important.This may affect the patient’s drug clearance due to GST activity,loss of GSH,or the interactions with GSH-conjugated drugs.Moreover,GST-mediated depletion of cellular GSH may increase tumor cell exposure to reactive products of UA metabolic transformations.
文摘A new unsymmetrical Schiff base ligand (H2LLi) was synthesized using L-lysine, salicylaldehyde and 2-hydroxy-1-naphthaldehyde. Three solid metal complexes of this ligand \[Ln(H2L)(NO3)\] NO3·2H2O (Ln=La, Sm, Ho) have been prepared and characterized by elemental analyses, IR spectra, UV spectra, TG-DTG and molar conductance. The antibacterial activities of the ligand and its complexes are also studied. The antibacterial experiments indicate that the ligand and its complexes possess antibacterial activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis and that the complexes have higher activity than those of the ligand.
基金supported by the National Natural Science Foundation of China (No. 51078318)
文摘In order to study the unsymmetrical load effect in geological bedding strata for the Muzhailing tunnel on the Lanzhou-Chongqing passenger dedicated line in China, we investigated the deformation, mechanical response and pressure of the surrounding rock and the mechanical characteristics of bolts of the tunnel. The results suggest that open zones appear at arch and invert where joints open up, when layered stratum is horizontal, or when the dip angle of in- clined bedding is small. Open zones occur perpendicular to a joint. The failure mode is bending disjunction at the arch tain shear displacement, and lead to obvious geological bedding unsymmetrical load. The failure mode is shear damage. For the joint dip angle in the range of 75-90°, the failure mode is flexural crushing at the wall and vertical shear rup- ture above the arch. The restraining effect of two sides weakens for vertical dip. On the whole, shear failure instabilitytrend would occur and the tunnel collapses evenly. When the angle between the bolt and structure plane is greater than 23°, bolts can enhance the shearing stiffness of joint plane. Unfortunately, in the general purpose graph of tunnel for 250 km/h of passenger dedicated lines, the bolts have equal length and spacing. The rationale behind this is worthy offurther study. For inclined bedding, the surrounding rock pressure at the left wall is more than that at the right wall. In addition, lining is likely to be damaged at left shoulder and side wall. With the dip angle increasing, the unsymmetrical load gradually achieves symmetry. Asymmetry design for support is recommended to reduce the unsymmetrical load on lining disturbed by excavation.
基金National Natural Science Foundation of China(Nos.U20041101,21772034,U1704251)the Top-notch Personnel Fund of Henan Agricultural University(No.30500418)for financial support。
文摘A novel thiazolothiazole-bridged imidazole derivative(1) was found to exhibit blue fluorescence in gaseous state or in methanol and yellow fluorescence in solid state. The N-alkylation of imidazole subunit(s) in 1 using n-propyl iodide generated unsymmetrically or symmetrically alkylated thiazolothiazolebridged imidazolium salts with good water solubility and remarkably strong emission in solution. Furthermore, the replacement of iodide counter-anion by triflate or bis(trifluoromethane sulfonyl)imide achieved remarkably strong emission in solid state and in solution as well as good water solubility. The strong fluorescence of dicationic salts with triflate and NTf_(2)^(-)counter-anions in solid state can be ascribed to their twisted and rigid structures induced by interionic C-H···F hydrogen bonding.
文摘A new unsymmetrical solid Schiff base (LLi) was synthesized using L-lysine, o-vanillin and 2-hydroxy-l-naphthaldehyde. Solid La(Ⅲ) complex of this ligand [LaL(NO3)](NO3)·2H2O was prepared and characterized by elemental analyses, IR, UV and molar conductance. The thermal decomposition kinetics of the complex for the second stage were studied under non-isothermal condition by TG and DTG methods. The kinetic equation may be expressed as: dα/dt=A·e-E/RT·(1-α)2. The kinetic parameters(E, A), activation entropy S≠ and activation free-energy G≠ were also gained.
文摘A new unsymmetrical Schiff base ligand (H_2LLi) was synthesized using L-lysine, o-vanillin and salicylaladyde. Three solid metal complexes of this ligand [Ln(H_2L)(NO_3)] NO_3·2H_2O (Ln=Sm, Ho, Tm) were prepared and characterized by elemental analyses, IR spectra, UV spectra, TG-DTG and molar conductance. The ligand synthesized are chelating agent. The nitrogen atoms of Schiff base, oxygen atoms of hydroxybenzene, methoxide and carboxyl are all coordinated to the metal ions. Carboxyl and the nitrate ion within the coordination sphere are coordinated to the metal ion in a mondentate or bidentate fashion. Water molecules are lied in crystal substances. The antibacterial activity of the ligand and its complexes was also studied. The antibacterial experiments indicate that they have antibacterial activity to E. coli, S. aureus, B. subtilis and the complexes have higher activity than the ligand.
基金The project supported by National Natural Science Foundation of China under Grant Nos. 60472018 and 10547125
文摘An unsymmetrical quantum key distribution protocol is proposed, in which Greenherger-Horne-Zeilinger （GHZ） triplet states are used to obtain the secret key. Except the lost qubits due to the unperfectness of the physical devices, the unsymmetrical characteristic makes all transmitted qubits useful. This leads to：an excellent efficiency, which reaches 100% in an ideal case. The ＇security is studied from the aspect of information theory. By using the correlation of the GHZ tripartite entanglement state, eavesdropping can be easily checked out, which indicates that the presented protocol is more secure.
基金This project is supported by National Key Project of China(No.PD9521901).
文摘The 1/2 subharmonic resonance of a shaft with unsymmetrical stiffness is studied. By means of the Hamilton's principle the nonlinear differential equations of motion of the rotating shaft are derived in the rotating rectangular coordinate system. Transforming the equations of motion from rotating coordinate system into stationary coordinate system and introducing a complex variable, the equation of motion in complex variable form is obtained, in which the stiffness coefficient varies periodically with time. It presents a nonlinear oscillation system under parametric excitation. By applying the method of multiple scales (MMS) the averaged equation, the bifurcating response equations and local bifurcating set are obtained. Via the theory of singularity, the stability of constant solutions is analyzed and bifurcating response curves are obtained. This study shows that the rotating shaft has rich bifurcation phenomena.
基金the National Natural Science Foundation of China(No.20902070)Natural Science Foundation of Zhejiang Province(No.Y4100579)Qianjiang Talents Program of Zhejiang Province(No.QJD0902004) for financial supports
文摘Tetrabutylammonium fluoride （TBAF） effectively facilitated a denitrative substitution reaction of electron-deficient nitroarenes with phenylthiotrimethylsilane （PhSTMS） under mild and base-free neutral conditions at room temperature, providing a practical and efficient synthesis of useful unsymmetrical diaryl thioethers. Nitroarenes bearing ortho- and para-positioned electron-withdrawing groups are the most reactive substrates, indicating that this reaction most possibly proceeded via the nucleophilic aromatic substitution （SNAr） mechanism.
