Small worm effects in the harmonious unifying hybrid preferential model （HUHPM） networks are studied both numerically and analytically. The idea and method of the HUHPM is applied to three typical examples of unweig...Small worm effects in the harmonious unifying hybrid preferential model （HUHPM） networks are studied both numerically and analytically. The idea and method of the HUHPM is applied to three typical examples of unweighted BA model, weighted BBV model, and the TDE rnodel, so-called HUHPM-BA, HUHPM-BBV and HUHPM- TDE networks. Comparing the HUHPM with current typical models above, it is found that the HUHPM networks has the smallest average path length and the biggest average clustering coefficient. The results demonstrate that the HUHPM is more suitable not only for the un-iveighted models but also for the weighted models.展开更多
This paper modifies the Farnes’ unifying theory of dark energy and dark matter which are negative-mass, created continuously from the negative-mass universe in the positive-negative mass universe pair. The first modi...This paper modifies the Farnes’ unifying theory of dark energy and dark matter which are negative-mass, created continuously from the negative-mass universe in the positive-negative mass universe pair. The first modification explains that observed dark energy is 68.6%, greater than 50% for the symmetrical positive-negative mass universe pair. This paper starts with the proposed positive-negative-mass 11D universe pair (without kinetic energy) which is transformed into the positive-negative mass 10D universe pair and the external dual gravities as in the Randall-Sundrum model, resulting in the four equal and separate universes consisting of the positive-mass 10D universe, the positive-mass massive external gravity, the negative-mass 10D universe and the negative-mass massive external gravity. The positive-mass 10D universe is transformed into 4D universe (home universe) with kinetic energy through the inflation and the Big Bang to create positive-mass dark matter which is five times of positive-mass baryonic matter. The other three universes without kinetic energy oscillate between 10D and 10D through 4D, resulting in the hidden universes when D > 4 and dark energy when D = 4, which is created continuously to our 4D home universe with the maximum dark energy = 3/4 = 75%. In the second modification to explain dark matter in the CMB, dark matter initially is not repulsive. The condensed baryonic gas at the critical surface density induces dark matter repulsive force to transform dark matter in the region into repulsive dark matter repulsing one another. The calculated percentages of dark energy, dark matter, and baryonic matter are 68.6 (as an input from the observation), 26 and 5.2, respectively, in agreement with observed 68.6, 26.5 and 4.9, respectively, and dark energy started in 4.33 billion years ago in agreement with the observed 4.71 <span style="white-space:nowrap;">±</span> 0.98 billion years ago. In conclusion, the modified Farnes’ unifying theory reinterprets the Farnes’ equations, and is a unifying theory of dark energy, dark matter, and baryonic matter in the positive-negative mass universe pair. The unifying theory explains protogalaxy and galaxy evolutions in agreement with the observations.展开更多
An agreement signed in Kigali, capital of Rwanda, has caught the world＇s attention. On March 21, a total of 44 African countries agreed to establish the African Continental Free Trade Area （AfCFTA）, aimed at creat ...An agreement signed in Kigali, capital of Rwanda, has caught the world＇s attention. On March 21, a total of 44 African countries agreed to establish the African Continental Free Trade Area （AfCFTA）, aimed at creat ing a single continental market for goods and services with free movement of busi nesses and investments. The agreement, signed at the 10th Extraordinary Session of the Assembly of the African Union （AU）, wlll be submitted for ratification by state parties in accordance with their domestic laws.展开更多
Media has the ability to play an important role in providing readers with information with which to shape opinions, drive initiatives and open discussion on a wide variety of topics.ChinAfrica reader, Christopher S.A....Media has the ability to play an important role in providing readers with information with which to shape opinions, drive initiatives and open discussion on a wide variety of topics.ChinAfrica reader, Christopher S.A.Gonolinje.展开更多
Objective.The objective of this research is to unify the molecular representations of spatial transcriptomics and cellular scale histology with the tissue scales of computational anatomy for brain mapping.Impact State...Objective.The objective of this research is to unify the molecular representations of spatial transcriptomics and cellular scale histology with the tissue scales of computational anatomy for brain mapping.Impact Statement.We present a unified representation theory for brain mapping based on geometric varifold measures of the microscale deterministic structure and function with the statistical ensembles of the spatially aggregated tissue scales.Introduction.Mapping across coordinate systems in computational anatomy allows us to understand structural and functional properties of the brain at the millimeter scale.New measurement technologies in digital pathology and spatial transcriptomics allow us to measure the brain molecule by molecule and cell by cell based on protein and transcriptomic functional identity.We currently have no mathematical representations for integrating consistently the tissue limits with the molecular particle descriptions.The formalism derived here demonstrates the methodology for transitioning consistently from the molecular scale of quantized particles—using mathematical structures as first introduced by Dirac as the class of generalized functions—to the tissue scales with methods originally introduced by Euler for fluids.Methods.We introduce two mathematical methods based on notions of generalized functions and statistical mechanics.We use geometric varifolds,a product measure on space and function,to represent functional states at the micro-scales—electrophysiology,molecular histology—integrated with a Boltzmann-like program to pass from deterministic particle descriptions to empirical probabilities on the functional states at the tissue scales.Results.Our space-function varifold representation provides a recipe for traversing from molecular to tissue scales in terms of a cascade of linear space scaling composed with nonlinear functional feature mapping.Following the cascade implies every scale is a geometric measure so that a universal family of measure norms can be introduced which quantifies the geodesic connection between brains in the orbit independent of the probing technology,whether it be RNA identities,Tau or amyloid histology,spike trains,or dense MR imagery.Conclusions.We demonstrate a unified brain mapping theory for molecular and tissue scales based on geometric measure representations.We call the consistent aggregation of tissue scales from particle and cellular scales,molecular computational anatomy.展开更多
Event extraction extracts event frames from text, while grounded situation recognition detects events in images. As real-world applications frequently encounter a multitude of unforeseen events, certain researchers ha...Event extraction extracts event frames from text, while grounded situation recognition detects events in images. As real-world applications frequently encounter a multitude of unforeseen events, certain researchers have introduced cross-domain and in-domain event extraction, while grounded situation recognition primarily explores in-domain scenarios. Therefore, in this paper, we propose cross-domain grounded situation recognition and establish a new benchmark SWiG-XD. In this more challenging setting, we deepen the connection between the two tasks based on their underlying unity in two different modalities and explore how to transfer the generalization ability from text to images. Firstly, we utilize ChatGPT to automatically generate textual data, which can be divided into two categories. One category is directly matched with images, establishing a direct connection with the images. The other category encompasses all event types and possesses greater generalization. Then we employ a unified model framework to establish the association between textual concepts and local image features and achieve cross-domain generalization transfer across modalities through modality-shared prompts and self-attention mechanism. Furthermore, we incorporate textual data with higher generalization to further assist in improving generalization on images. The experimental results on the newly constructed benchmark demonstrate the effectiveness of our method.展开更多
对珠子参中皂苷类成分进行定性鉴别分析,建立珠子参皂苷类多成分含量测定方法。采用超高效液相色谱-飞行时间质谱(UPLC-Q-TOF-MS/MS)技术对珠子参进行正、负离子模式扫描,使用UNIFI天然产物信息平台对珠子参所含的化学成分进行定性鉴别...对珠子参中皂苷类成分进行定性鉴别分析,建立珠子参皂苷类多成分含量测定方法。采用超高效液相色谱-飞行时间质谱(UPLC-Q-TOF-MS/MS)技术对珠子参进行正、负离子模式扫描,使用UNIFI天然产物信息平台对珠子参所含的化学成分进行定性鉴别分析;以0.1%磷酸水-乙腈溶液为流动相进行梯度洗脱,柱温30℃,流速0.3 mL/min,进行珠子参皂苷类多成分含量测定。珠子参中共鉴定出39个化学成分,包括37个皂苷类化合物和2个皂苷母核,并总结了皂苷类化合物的裂解规律,建立了UPLC同时测定珠子参中人参皂苷Rb1、人参皂苷Ro、人参皂苷Rb3、竹节参皂苷IV、竹节参皂苷IVa、人参皂苷Rd、姜状三七皂苷R1和金盏花苷E的多指标含量测定方法,该方法中8个待测成分在检测质量浓度范围内线性关系良好,精密度、重复性、稳定性的相对标准偏差(relative standard deviation,RSD)均小于3.0%,样品中人参皂苷Rb1、人参皂苷Ro、人参皂苷Rb3、竹节参皂苷IV、竹节参皂苷IVa、人参皂苷Rd、姜状三七皂苷R1和金盏花苷E的平均加样回收率分别为102.4%、103.1%、97.97%、99.42%、102.7%、102.1%、95.23%、100.5%,RSD分别为1.0%、0.98%、0.81%、2.3%、0.81%、1.9%、0.96%、1.8%。该研究建立的方法可快速、准确地对珠子参中的皂苷类成分进行定性及定量分析。展开更多
To describe the real world which is a harmonious unification world with both de- terminism and randomness, we propose a harmonious unifying hybrid preferential model (HUHPM) of a certain class of complex dynamical net...To describe the real world which is a harmonious unification world with both de- terminism and randomness, we propose a harmonious unifying hybrid preferential model (HUHPM) of a certain class of complex dynamical networks. HUHPM is gov- erned only by the total hybrid ratio d/r according to the practical need. As some typical examples, the concepts and methods of the HUHPM are applied to the un-weighted BA model proposed by Barabási et al., the weighted BBV model pro- posed by Barat et al. and the weighted TDE model proposed by Wang et al. to get the so-called HUHPM-BA network, HUHPM-BBV network and HUHPM-TDE network. These HUHPM networks are investigated both analytically and numerically. It is found that the HUHPM reveals several universal properties, which more approach to the real-world networks for both un-weighted and weighted networks and have potential for applications.展开更多
If the singularity of the cosmic Big Bang is taken as the origin of the reference coordinate system,the surrounding vacuum in the initial moments of it would exhibit radially-outward right-handed spiral motion at ligh...If the singularity of the cosmic Big Bang is taken as the origin of the reference coordinate system,the surrounding vacuum in the initial moments of it would exhibit radially-outward right-handed spiral motion at light speed.Based on this spatial motion hypothesis,we derive a unified field equation and a set of Maxwell’s equations for vacuum SWs(Scalar Waves)generating a huge spiral force field that drives the energy to spiral inwardly and distort,leading to the formation of mass.Furthermore,they also uncover that mass is fundamentally an ultimate expression of energy,manifesting as the result of spiral motion of space at light speed.And then,we indirectly validate the theory that coherent light waves’collision generate SWs and subsequently mass through the experiment verifying the Breit-Wheeler process.The establishment of our theory offers a new analytical tool for the exploration of mass origin,the cosmic Big Bang,unified field theories.展开更多
Downloads of national standards exceed 10 million times in the first half of 2025 In response to social needs,State Administration for Market Regulation(SAMR)had steadily promoted the full-text disclosure and free dow...Downloads of national standards exceed 10 million times in the first half of 2025 In response to social needs,State Administration for Market Regulation(SAMR)had steadily promoted the full-text disclosure and free download of over 30,000 national standards that do not adopt international standards since the beginning of this year.In the first half of 2025,downloads exceeded 10 million times,providing strong support for the construction of a unified national market.Social groups accessing national standards for free increased significantly.In the first half of this year,the average monthly downloads of national standards surged tenfold from 190,000 times last year to 2.03 million times.Online reading reached nearly 15 million times,and page views hit 89 million times.The disclosure of national standards for free has effectively broken information barriers in standards,ensuring equal rights for business entities to read and download national standards.展开更多
Vehicle recognition plays a vital role in intelligent transportation systems,law enforcement,access control,and security operations—domains that are becoming increasingly dynamic and complex.Despite advancements,most...Vehicle recognition plays a vital role in intelligent transportation systems,law enforcement,access control,and security operations—domains that are becoming increasingly dynamic and complex.Despite advancements,most existing solutions remain siloed,addressing individual tasks such as vehicle make and model recognition(VMMR),automatic number plate recognition(ANPR),and color classification separately.This fragmented approach limits real-world efficiency,leading to slower processing,reduced accuracy,and increased operational costs,particularly in traffic monitoring and surveillance scenarios.To address these limitations,we present a unified framework that consolidates all three recognition tasks into a single,lightweight system.The framework utilizes MobileNetV2 for efficient VMMR,YOLO(You Only Look Once)for accurate license plate detection,and histogram-based clustering in the HSV color space for precise color identification.Rather than optimizing each module in isolation,our approach emphasizes tight integration,enabling improved performance and reliability.The system also features adaptive image calibration and robust algorithmic enhancements to ensure consistent results under varying environmental conditions.Experimental evaluations demonstrate that the proposedmodel achieves a combined accuracy of 93.3%,outperforming traditional methods and offering practical scalability for deployment in real-world transportation infrastructures.展开更多
As important natural and pharmaceutical motifs,the catalytic construction of structurally diverse 3,3-disubstituted oxindoles often requires elaborate synthetic efforts on optimizations.Herein,we developed a simple an...As important natural and pharmaceutical motifs,the catalytic construction of structurally diverse 3,3-disubstituted oxindoles often requires elaborate synthetic efforts on optimizations.Herein,we developed a simple and divergent approach for constructing reverse-prenylated and prenylated oxindoles launched by Ni catalysis with bulk chemical isoprene.Using C3-unsubstituted oxindoles as starting materials,mono reverse-prenylation was demonstrated in high chemo-and regioselectivities facilitated by the combination of Ni(0)and monodentate phosphine ligand.Using the obtained reverse-prenylated oxindoles as versatile synthon,substitutions at the pseudobenzylic position with various electrophiles created vicinal quaternary centers in a concise way.With the help of additives(PPh3 and NaH),air could be directly used as green oxidant to construct prenylated and reverse-prenylatedα-hydroxy-oxindoles divergently from the same substrates.In situ esterification of prenylatedα-hydroxy-oxindoles allowed subsequent Friedel-Crafts substitutions with diverse nucleophiles to deliver prenyl substituted dimeric or spiro-oxindoles.This protocol provides a divergent synthetic approach for the construction of highly functionalized 3,3-disubstituted oxindoles,which have been otherwise difficult to access in a unified approach.展开更多
Ground reinforcement is crucial for tunnel construction, especially in soft rock tunnels. Existing analytical models are inadequate for predicting the ground reaction curves (GRCs) for reinforced tunnels in strain-sof...Ground reinforcement is crucial for tunnel construction, especially in soft rock tunnels. Existing analytical models are inadequate for predicting the ground reaction curves (GRCs) for reinforced tunnels in strain-softening (SS) rock masses. This study proposes a novel analytical model to determine the GRCs of SS rock masses, incorporating ground reinforcement and intermediate principal stress (IPS). The SS constitutive model captures the progressive post- peak failure, while the elastic-brittle model simulates reinforced rock masses. Nine combined states are innovatively investigated to analyze plastic zone development in natural and reinforced regions. Each region is analyzed separately, and coupled through boundary conditions at interface. Comparison with three types of existing models indicates that these models overestimate reinforcement effects. The deformation prediction errors of single geological material models may exceed 75%. Furthermore, neglecting softening and residual zones in natural regions could lead to errors over 50%. Considering the IPS can effectively utilize the rock strength to reduce tunnel deformation by at least 30%, thereby saving on reinforcement and support costs. The computational results show a satisfactory agreement with the monitoring data from a model test and two tunnel projects. The proposed model may offer valuable insights into the design and construction of reinforced tunnel engineering.展开更多
The stress gradient of surrounding rock and reasonable prestress of support are the keys to ensuring the stability of roadways.The elastic-plastic analytical solution for surrounding rock was derived based on unified ...The stress gradient of surrounding rock and reasonable prestress of support are the keys to ensuring the stability of roadways.The elastic-plastic analytical solution for surrounding rock was derived based on unified strength theory.A model for solving the stress gradient of the surrounding rock with the intermediate principal stress parameter b was established.The correctness and applicability of the solution for the stress gradient in the roadway surrounding rock was verified via multiple methods.Furthermore,the laws of stress,displacement,and the plastic zone of the surrounding rock with different b values and prestresses were revealed.As b increases,the stress gradient in the plastic zone increases,and the displacement and plastic zone radius decrease.As the prestress increases,the peak stress shifts toward the sidewalls,and the stress and stress gradient increments decrease.In addition,the displacement increment and plastic zone increment were proposed to characterize the support effect.The balance point of the plastic zone area appears before that of the displacement zone.The relationship between the stress gradient compensation coefficient and the prestress is obtained.This study provides a research method and idea for determining the reasonable prestress of support in roadways.展开更多
This paper presents a multi-scale experimental investigation of the weathering degradation of red mudstone.Natural rocks were extracted from the surface ground to 120 m,inwhich three sets of samples were selected to c...This paper presents a multi-scale experimental investigation of the weathering degradation of red mudstone.Natural rocks were extracted from the surface ground to 120 m,inwhich three sets of samples were selected to consider the different initial rock fabrics.The long-term relative humidity(RH)cycles under two amplitudes were imposed on red mudstone to simulate the weathering process.After RH cycles,a series of uniaxial compression tests,Brazilian splitting tests and bender-extender element tests were carried out to examine the reduction in strength and stiffness.The objective of this study is to develop an extended stress-volume framework characterizing the degradation of natural red mudstone both at microscale and macroscale.Accompanied by the irreversible swelling of the rock specimen is the progressive degradation of strength,stiffness and Poisson's ratio.A unified exponential degradation model in terms of the irreversible volumetric strain was thus proposed to capture such a degradation pattern.The effect of the initial rock fabric was evident.The highest degradation rate and potential were identified in slightly weathered specimens.Significant slaking of aggregates and crack propagation were confirmed by scanning electron microscope(SEM)micrographs,which were considered as the main consequence of structure damage leading to degradation of mechanical properties.The structure damage during RH cycles denoted the hysteresis nature in the response to the cycling hydraulic reaction,in turn causing the increase in volumetric strain.Thus,the stress-volume relation rather than the suction relation was found in more reasonable agreement with the experimental results.展开更多
Model-based system-of-systems(SOS)engineering(MBSoSE)is becoming a promising solution for the design of SoS with increasing complexity.However,bridging the models from the design phase to the simulation phase poses si...Model-based system-of-systems(SOS)engineering(MBSoSE)is becoming a promising solution for the design of SoS with increasing complexity.However,bridging the models from the design phase to the simulation phase poses significant challenges and requires an integrated approach.In this study,a unified requirement modeling approach is proposed based on unified architecture framework(UAF).Theoretical models are proposed which compose formalized descriptions from both topdown and bottom-up perspectives.Based on the description,the UAF profile is proposed to represent the SoS mission and constituent systems(CS)goal.Moreover,the agent-based simulation information is also described based on the overview,design concepts,and details(ODD)protocol as the complement part of the SoS profile,which can be transformed into different simulation platforms based on the eXtensible markup language(XML)technology and model-to-text method.In this way,the design of the SoS is simulated automatically in the early design stage.Finally,the method is implemented and an example is given to illustrate the whole process.展开更多
This study discusses the benefits and challenges of well monitoring for Gulong shale oil production.It examines the Unified Transient Analysis(UTA)method,which integrates rate and pressure data to monitor changes in f...This study discusses the benefits and challenges of well monitoring for Gulong shale oil production.It examines the Unified Transient Analysis(UTA)method,which integrates rate and pressure data to monitor changes in fracture surface area and production efficiency in real-time.The UTA method allows for early detection of production impairments and provides feedback to optimize drawdown pressure,enhancing production without damaging fracture conductivity.Analysis of production data from Well A in the Daqing Oilfield demonstrates the method's efficacy,particularly in managing choke size adjustments and identifying fracture conductivity degradation.Despite its benefits,challenges such as data quality,manual data analysis,and the need for automated choke management are highlighted.The study underscores the necessity of integrating intelligent monitoring technologies and automating workflows to optimize Gulong shale oil production.展开更多
基金The project supported by National Natural Science Foundation of China under Grant Nos. 70431002 and 70371068
文摘Small worm effects in the harmonious unifying hybrid preferential model （HUHPM） networks are studied both numerically and analytically. The idea and method of the HUHPM is applied to three typical examples of unweighted BA model, weighted BBV model, and the TDE rnodel, so-called HUHPM-BA, HUHPM-BBV and HUHPM- TDE networks. Comparing the HUHPM with current typical models above, it is found that the HUHPM networks has the smallest average path length and the biggest average clustering coefficient. The results demonstrate that the HUHPM is more suitable not only for the un-iveighted models but also for the weighted models.
文摘This paper modifies the Farnes’ unifying theory of dark energy and dark matter which are negative-mass, created continuously from the negative-mass universe in the positive-negative mass universe pair. The first modification explains that observed dark energy is 68.6%, greater than 50% for the symmetrical positive-negative mass universe pair. This paper starts with the proposed positive-negative-mass 11D universe pair (without kinetic energy) which is transformed into the positive-negative mass 10D universe pair and the external dual gravities as in the Randall-Sundrum model, resulting in the four equal and separate universes consisting of the positive-mass 10D universe, the positive-mass massive external gravity, the negative-mass 10D universe and the negative-mass massive external gravity. The positive-mass 10D universe is transformed into 4D universe (home universe) with kinetic energy through the inflation and the Big Bang to create positive-mass dark matter which is five times of positive-mass baryonic matter. The other three universes without kinetic energy oscillate between 10D and 10D through 4D, resulting in the hidden universes when D > 4 and dark energy when D = 4, which is created continuously to our 4D home universe with the maximum dark energy = 3/4 = 75%. In the second modification to explain dark matter in the CMB, dark matter initially is not repulsive. The condensed baryonic gas at the critical surface density induces dark matter repulsive force to transform dark matter in the region into repulsive dark matter repulsing one another. The calculated percentages of dark energy, dark matter, and baryonic matter are 68.6 (as an input from the observation), 26 and 5.2, respectively, in agreement with observed 68.6, 26.5 and 4.9, respectively, and dark energy started in 4.33 billion years ago in agreement with the observed 4.71 <span style="white-space:nowrap;">±</span> 0.98 billion years ago. In conclusion, the modified Farnes’ unifying theory reinterprets the Farnes’ equations, and is a unifying theory of dark energy, dark matter, and baryonic matter in the positive-negative mass universe pair. The unifying theory explains protogalaxy and galaxy evolutions in agreement with the observations.
文摘An agreement signed in Kigali, capital of Rwanda, has caught the world＇s attention. On March 21, a total of 44 African countries agreed to establish the African Continental Free Trade Area （AfCFTA）, aimed at creat ing a single continental market for goods and services with free movement of busi nesses and investments. The agreement, signed at the 10th Extraordinary Session of the Assembly of the African Union （AU）, wlll be submitted for ratification by state parties in accordance with their domestic laws.
文摘Media has the ability to play an important role in providing readers with information with which to shape opinions, drive initiatives and open discussion on a wide variety of topics.ChinAfrica reader, Christopher S.A.Gonolinje.
基金supported by the National Institutes of Health (NIH) (http://www.nih.gov)grants R01EB020062 (MM),R01NS102670 (MM),U19AG033655 (MM),P41-EB031771 (MM and Tward),and R01MH105660 (MM)the National Science Foundation (NSF) (http://www.nsf.gov)16-569 NeuroNex contract 1707298 (MM)+3 种基金supported by the NSF grant ACI1548562Johns Hopkins University Alzheimer’s Disease Research Center with NIH grant P50AG05146the Dana Foundation’s (http://www.dana.org)clinical neuroscience research programthe Kavli Neuroscience Discovery Institute (http://kavlijhu.org)supported by the Kavli Foundation (http://www.kavlifoundation.org) (MM and DT).
文摘Objective.The objective of this research is to unify the molecular representations of spatial transcriptomics and cellular scale histology with the tissue scales of computational anatomy for brain mapping.Impact Statement.We present a unified representation theory for brain mapping based on geometric varifold measures of the microscale deterministic structure and function with the statistical ensembles of the spatially aggregated tissue scales.Introduction.Mapping across coordinate systems in computational anatomy allows us to understand structural and functional properties of the brain at the millimeter scale.New measurement technologies in digital pathology and spatial transcriptomics allow us to measure the brain molecule by molecule and cell by cell based on protein and transcriptomic functional identity.We currently have no mathematical representations for integrating consistently the tissue limits with the molecular particle descriptions.The formalism derived here demonstrates the methodology for transitioning consistently from the molecular scale of quantized particles—using mathematical structures as first introduced by Dirac as the class of generalized functions—to the tissue scales with methods originally introduced by Euler for fluids.Methods.We introduce two mathematical methods based on notions of generalized functions and statistical mechanics.We use geometric varifolds,a product measure on space and function,to represent functional states at the micro-scales—electrophysiology,molecular histology—integrated with a Boltzmann-like program to pass from deterministic particle descriptions to empirical probabilities on the functional states at the tissue scales.Results.Our space-function varifold representation provides a recipe for traversing from molecular to tissue scales in terms of a cascade of linear space scaling composed with nonlinear functional feature mapping.Following the cascade implies every scale is a geometric measure so that a universal family of measure norms can be introduced which quantifies the geodesic connection between brains in the orbit independent of the probing technology,whether it be RNA identities,Tau or amyloid histology,spike trains,or dense MR imagery.Conclusions.We demonstrate a unified brain mapping theory for molecular and tissue scales based on geometric measure representations.We call the consistent aggregation of tissue scales from particle and cellular scales,molecular computational anatomy.
基金supported by National Natural Science Foundation of China(No.62176058)National Key RD Program of China(2023YFF1204800).
文摘Event extraction extracts event frames from text, while grounded situation recognition detects events in images. As real-world applications frequently encounter a multitude of unforeseen events, certain researchers have introduced cross-domain and in-domain event extraction, while grounded situation recognition primarily explores in-domain scenarios. Therefore, in this paper, we propose cross-domain grounded situation recognition and establish a new benchmark SWiG-XD. In this more challenging setting, we deepen the connection between the two tasks based on their underlying unity in two different modalities and explore how to transfer the generalization ability from text to images. Firstly, we utilize ChatGPT to automatically generate textual data, which can be divided into two categories. One category is directly matched with images, establishing a direct connection with the images. The other category encompasses all event types and possesses greater generalization. Then we employ a unified model framework to establish the association between textual concepts and local image features and achieve cross-domain generalization transfer across modalities through modality-shared prompts and self-attention mechanism. Furthermore, we incorporate textual data with higher generalization to further assist in improving generalization on images. The experimental results on the newly constructed benchmark demonstrate the effectiveness of our method.
文摘对珠子参中皂苷类成分进行定性鉴别分析,建立珠子参皂苷类多成分含量测定方法。采用超高效液相色谱-飞行时间质谱(UPLC-Q-TOF-MS/MS)技术对珠子参进行正、负离子模式扫描,使用UNIFI天然产物信息平台对珠子参所含的化学成分进行定性鉴别分析;以0.1%磷酸水-乙腈溶液为流动相进行梯度洗脱,柱温30℃,流速0.3 mL/min,进行珠子参皂苷类多成分含量测定。珠子参中共鉴定出39个化学成分,包括37个皂苷类化合物和2个皂苷母核,并总结了皂苷类化合物的裂解规律,建立了UPLC同时测定珠子参中人参皂苷Rb1、人参皂苷Ro、人参皂苷Rb3、竹节参皂苷IV、竹节参皂苷IVa、人参皂苷Rd、姜状三七皂苷R1和金盏花苷E的多指标含量测定方法,该方法中8个待测成分在检测质量浓度范围内线性关系良好,精密度、重复性、稳定性的相对标准偏差(relative standard deviation,RSD)均小于3.0%,样品中人参皂苷Rb1、人参皂苷Ro、人参皂苷Rb3、竹节参皂苷IV、竹节参皂苷IVa、人参皂苷Rd、姜状三七皂苷R1和金盏花苷E的平均加样回收率分别为102.4%、103.1%、97.97%、99.42%、102.7%、102.1%、95.23%、100.5%,RSD分别为1.0%、0.98%、0.81%、2.3%、0.81%、1.9%、0.96%、1.8%。该研究建立的方法可快速、准确地对珠子参中的皂苷类成分进行定性及定量分析。
基金Supported by the Key Project of the National Natural Science Foundation of China (Grand No. 70431002)the National Natural Science Foundation of China (Grand No. 70371068)
文摘To describe the real world which is a harmonious unification world with both de- terminism and randomness, we propose a harmonious unifying hybrid preferential model (HUHPM) of a certain class of complex dynamical networks. HUHPM is gov- erned only by the total hybrid ratio d/r according to the practical need. As some typical examples, the concepts and methods of the HUHPM are applied to the un-weighted BA model proposed by Barabási et al., the weighted BBV model pro- posed by Barat et al. and the weighted TDE model proposed by Wang et al. to get the so-called HUHPM-BA network, HUHPM-BBV network and HUHPM-TDE network. These HUHPM networks are investigated both analytically and numerically. It is found that the HUHPM reveals several universal properties, which more approach to the real-world networks for both un-weighted and weighted networks and have potential for applications.
文摘If the singularity of the cosmic Big Bang is taken as the origin of the reference coordinate system,the surrounding vacuum in the initial moments of it would exhibit radially-outward right-handed spiral motion at light speed.Based on this spatial motion hypothesis,we derive a unified field equation and a set of Maxwell’s equations for vacuum SWs(Scalar Waves)generating a huge spiral force field that drives the energy to spiral inwardly and distort,leading to the formation of mass.Furthermore,they also uncover that mass is fundamentally an ultimate expression of energy,manifesting as the result of spiral motion of space at light speed.And then,we indirectly validate the theory that coherent light waves’collision generate SWs and subsequently mass through the experiment verifying the Breit-Wheeler process.The establishment of our theory offers a new analytical tool for the exploration of mass origin,the cosmic Big Bang,unified field theories.
文摘Downloads of national standards exceed 10 million times in the first half of 2025 In response to social needs,State Administration for Market Regulation(SAMR)had steadily promoted the full-text disclosure and free download of over 30,000 national standards that do not adopt international standards since the beginning of this year.In the first half of 2025,downloads exceeded 10 million times,providing strong support for the construction of a unified national market.Social groups accessing national standards for free increased significantly.In the first half of this year,the average monthly downloads of national standards surged tenfold from 190,000 times last year to 2.03 million times.Online reading reached nearly 15 million times,and page views hit 89 million times.The disclosure of national standards for free has effectively broken information barriers in standards,ensuring equal rights for business entities to read and download national standards.
基金supported in part by Multimedia University Research Fellow under Grant MMUI/250008in part by Telekom Research and Development Sdn Bhd under Grant RDTC/241149.
文摘Vehicle recognition plays a vital role in intelligent transportation systems,law enforcement,access control,and security operations—domains that are becoming increasingly dynamic and complex.Despite advancements,most existing solutions remain siloed,addressing individual tasks such as vehicle make and model recognition(VMMR),automatic number plate recognition(ANPR),and color classification separately.This fragmented approach limits real-world efficiency,leading to slower processing,reduced accuracy,and increased operational costs,particularly in traffic monitoring and surveillance scenarios.To address these limitations,we present a unified framework that consolidates all three recognition tasks into a single,lightweight system.The framework utilizes MobileNetV2 for efficient VMMR,YOLO(You Only Look Once)for accurate license plate detection,and histogram-based clustering in the HSV color space for precise color identification.Rather than optimizing each module in isolation,our approach emphasizes tight integration,enabling improved performance and reliability.The system also features adaptive image calibration and robust algorithmic enhancements to ensure consistent results under varying environmental conditions.Experimental evaluations demonstrate that the proposedmodel achieves a combined accuracy of 93.3%,outperforming traditional methods and offering practical scalability for deployment in real-world transportation infrastructures.
文摘As important natural and pharmaceutical motifs,the catalytic construction of structurally diverse 3,3-disubstituted oxindoles often requires elaborate synthetic efforts on optimizations.Herein,we developed a simple and divergent approach for constructing reverse-prenylated and prenylated oxindoles launched by Ni catalysis with bulk chemical isoprene.Using C3-unsubstituted oxindoles as starting materials,mono reverse-prenylation was demonstrated in high chemo-and regioselectivities facilitated by the combination of Ni(0)and monodentate phosphine ligand.Using the obtained reverse-prenylated oxindoles as versatile synthon,substitutions at the pseudobenzylic position with various electrophiles created vicinal quaternary centers in a concise way.With the help of additives(PPh3 and NaH),air could be directly used as green oxidant to construct prenylated and reverse-prenylatedα-hydroxy-oxindoles divergently from the same substrates.In situ esterification of prenylatedα-hydroxy-oxindoles allowed subsequent Friedel-Crafts substitutions with diverse nucleophiles to deliver prenyl substituted dimeric or spiro-oxindoles.This protocol provides a divergent synthetic approach for the construction of highly functionalized 3,3-disubstituted oxindoles,which have been otherwise difficult to access in a unified approach.
基金Projects(52208382, 52278387, 51738002) supported by the National Natural Science Foundation of ChinaProject(2022YJS072) supported by the Fundamental Research Funds for the Central Universities,China。
文摘Ground reinforcement is crucial for tunnel construction, especially in soft rock tunnels. Existing analytical models are inadequate for predicting the ground reaction curves (GRCs) for reinforced tunnels in strain-softening (SS) rock masses. This study proposes a novel analytical model to determine the GRCs of SS rock masses, incorporating ground reinforcement and intermediate principal stress (IPS). The SS constitutive model captures the progressive post- peak failure, while the elastic-brittle model simulates reinforced rock masses. Nine combined states are innovatively investigated to analyze plastic zone development in natural and reinforced regions. Each region is analyzed separately, and coupled through boundary conditions at interface. Comparison with three types of existing models indicates that these models overestimate reinforcement effects. The deformation prediction errors of single geological material models may exceed 75%. Furthermore, neglecting softening and residual zones in natural regions could lead to errors over 50%. Considering the IPS can effectively utilize the rock strength to reduce tunnel deformation by at least 30%, thereby saving on reinforcement and support costs. The computational results show a satisfactory agreement with the monitoring data from a model test and two tunnel projects. The proposed model may offer valuable insights into the design and construction of reinforced tunnel engineering.
基金Project(52274130)supported by the National Natural Science Foundation of ChinaProject(ZR2024ZD22)supported by the Major Basic Research Project of the Shandong Provincial Natural Science Foundation,China+2 种基金Project(2023375)supported by the Guizhou University Research and Innovation Team,ChinaProject(Leading Fund(2023)09)supported by the Natural Science Research Fund of Guizhou University,ChinaProject(JYBSYS2021101)supported by the Open Fund of Key Laboratory of Safe and Effective Coal Mining,Ministry of Education,China。
文摘The stress gradient of surrounding rock and reasonable prestress of support are the keys to ensuring the stability of roadways.The elastic-plastic analytical solution for surrounding rock was derived based on unified strength theory.A model for solving the stress gradient of the surrounding rock with the intermediate principal stress parameter b was established.The correctness and applicability of the solution for the stress gradient in the roadway surrounding rock was verified via multiple methods.Furthermore,the laws of stress,displacement,and the plastic zone of the surrounding rock with different b values and prestresses were revealed.As b increases,the stress gradient in the plastic zone increases,and the displacement and plastic zone radius decrease.As the prestress increases,the peak stress shifts toward the sidewalls,and the stress and stress gradient increments decrease.In addition,the displacement increment and plastic zone increment were proposed to characterize the support effect.The balance point of the plastic zone area appears before that of the displacement zone.The relationship between the stress gradient compensation coefficient and the prestress is obtained.This study provides a research method and idea for determining the reasonable prestress of support in roadways.
基金The financial support from Project(Grant Nos.52278432,and 52168066)of National Natural Science Foundation of China and Project(Grant No.K2023G033)of the Science and Technology Research and Development Plan of China National Railway Group Co.,Ltd.were greatly appreciated.
文摘This paper presents a multi-scale experimental investigation of the weathering degradation of red mudstone.Natural rocks were extracted from the surface ground to 120 m,inwhich three sets of samples were selected to consider the different initial rock fabrics.The long-term relative humidity(RH)cycles under two amplitudes were imposed on red mudstone to simulate the weathering process.After RH cycles,a series of uniaxial compression tests,Brazilian splitting tests and bender-extender element tests were carried out to examine the reduction in strength and stiffness.The objective of this study is to develop an extended stress-volume framework characterizing the degradation of natural red mudstone both at microscale and macroscale.Accompanied by the irreversible swelling of the rock specimen is the progressive degradation of strength,stiffness and Poisson's ratio.A unified exponential degradation model in terms of the irreversible volumetric strain was thus proposed to capture such a degradation pattern.The effect of the initial rock fabric was evident.The highest degradation rate and potential were identified in slightly weathered specimens.Significant slaking of aggregates and crack propagation were confirmed by scanning electron microscope(SEM)micrographs,which were considered as the main consequence of structure damage leading to degradation of mechanical properties.The structure damage during RH cycles denoted the hysteresis nature in the response to the cycling hydraulic reaction,in turn causing the increase in volumetric strain.Thus,the stress-volume relation rather than the suction relation was found in more reasonable agreement with the experimental results.
基金Fifth Electronic Research Institute of the Ministry of Industry and Information Technology(HK07202200877)Pre-research Project on Civil Aerospace Technologies of CNSA(D020101)+2 种基金Zhejiang Provincial Science and Technology Plan Project(2022C01052)Frontier Scientific Research Program of Deep Space Exploration Laboratory(2022-QYKYJHHXYF-018,2022-QYKYJH-GCXD-001)Zhiyuan Laboratory(ZYL2024001)。
文摘Model-based system-of-systems(SOS)engineering(MBSoSE)is becoming a promising solution for the design of SoS with increasing complexity.However,bridging the models from the design phase to the simulation phase poses significant challenges and requires an integrated approach.In this study,a unified requirement modeling approach is proposed based on unified architecture framework(UAF).Theoretical models are proposed which compose formalized descriptions from both topdown and bottom-up perspectives.Based on the description,the UAF profile is proposed to represent the SoS mission and constituent systems(CS)goal.Moreover,the agent-based simulation information is also described based on the overview,design concepts,and details(ODD)protocol as the complement part of the SoS profile,which can be transformed into different simulation platforms based on the eXtensible markup language(XML)technology and model-to-text method.In this way,the design of the SoS is simulated automatically in the early design stage.Finally,the method is implemented and an example is given to illustrate the whole process.
文摘This study discusses the benefits and challenges of well monitoring for Gulong shale oil production.It examines the Unified Transient Analysis(UTA)method,which integrates rate and pressure data to monitor changes in fracture surface area and production efficiency in real-time.The UTA method allows for early detection of production impairments and provides feedback to optimize drawdown pressure,enhancing production without damaging fracture conductivity.Analysis of production data from Well A in the Daqing Oilfield demonstrates the method's efficacy,particularly in managing choke size adjustments and identifying fracture conductivity degradation.Despite its benefits,challenges such as data quality,manual data analysis,and the need for automated choke management are highlighted.The study underscores the necessity of integrating intelligent monitoring technologies and automating workflows to optimize Gulong shale oil production.
