Objective: To observe the effect of electroacupuncture (EA) on learning and memory abilities and ultrastructure of synapses in CA3 region of the hippocampus in vascular dementia (VD) rats. Methods: A total of 32 SD ra...Objective: To observe the effect of electroacupuncture (EA) on learning and memory abilities and ultrastructure of synapses in CA3 region of the hippocampus in vascular dementia (VD) rats. Methods: A total of 32 SD rats were randomized into control (sham-operation, n=7), model (n=7), EA (n=9) and medication (n=9) groups. VD model was established by occlusion of the bilateral vertebral arteries (electrocoagulation) and bilateral common carotid arteries (occlusion for 5 min and reperfusion for 10 min , repeated the procedure for 3 times to induce global ischemia). EA ( 150 Hz , 1 mA ) was applied to “Baihui”(百会 GV 20), “Geshu”(膈俞 BL 17), “Pishu”(脾俞 BL 20) and “Shenshu”(肾俞 BL 23) for 20 min , once daily and continuously for 15 days. In medication group, the rats were fed with Nimotong (12 mg/kg), once daily and continuously for 15 days. Morris water maze method was used to test the animals’ learning and memory abilities (latencies to find the hidden platform determined by place navigation trials, and latencies to cross on the location of the removed platform determined by spatial probe trials) after the treatment. Ultrastructural changes (numerical density, N_A,surface density, Sv and volume density, Vv) of Gray type 1 synapses in CA3 region of the hippocampus were observed by using transmission electronic microscope and automatic image analysis system. Results: 1) Place navigation test showed that in comparison with control group, the average escape latency of VD group was significantly longer (P<0.01), while in comparison with VD group, the latencies of both EA and medication groups decreased significantly (P<0.01). No significant difference was found between EA and medication groups in the escape latency (P>0.05). 2) Spatial probe-test displayed that in comparison with control group, the times which the animals crossed the target platform in VD group decreased significantly (P<0.01), while compared with VD group, those of both EA and medication groups increased considerably (P<0.01). No significant differences were found between EA and medication groups in the times for rats to cross the target quadrant and among the 4 groups in the times for rats to cross the other quadrants. 3) Compared with control group, N_A, Sv, and Vv of VD group decreased significantly (P<0.01), while in comparison with VD group, the 3 indexes of both EA and medication groups increased significantly (P<0.01), no significant differences were found between EA and medication groups in these 3 indexes (P>0.05). Conclusion: EA can restrain the loss of Gray type Ⅰsynapses in CA3 region of the hippocampus to improve learning and memory abilities in VD rats.展开更多
It is shoum that the time-dependent intensity of an ultraehort laser puIse can recovered from the second-order correlation G^((2))(τ) and tthe third-order correlation with aingle time-delay G^((3))(τ).The recovery i...It is shoum that the time-dependent intensity of an ultraehort laser puIse can recovered from the second-order correlation G^((2))(τ) and tthe third-order correlation with aingle time-delay G^((3))(τ).The recovery is successfully carnied out by a computer with ingenious progrorming.展开更多
The use of antibacterial dressings is crucial in the prevention and treatment of wound infection in emergency sit-uations.However,the efficacy of dressings is compromised by long-term storage or exposure to harsh cond...The use of antibacterial dressings is crucial in the prevention and treatment of wound infection in emergency sit-uations.However,the efficacy of dressings is compromised by long-term storage or exposure to harsh conditions.Here,an ultrastable in-situ silver nanoparticle dressing(AgSNP@CD)was prepared for effective prevention and treatment of wound infection in emergency.The fabrication process of AgSNP@CD is simple,suitable for large-scale production.Due to the strong interaction between the in-situ synthesized AgNPs and the cotton fabric,AgSNP@CD owned remarkable stability,thus retaining its antimicrobial efficacy even after long-term storage(up to 2 years)and under extreme conditions(damp heat,low temperatures,low-oxygen,water immersion,acid-alkali erosion).Both in vitro and in vivo results demonstrated the extraordinary antibacterial efficacy and stability of AgSNP@CD,facilitating infection prevention and wound healing in extreme conditions.In particular,AgSNP@CD exhibited a superior treatment effect on severe bacteria-infected trauma and can prevent the occur-rence of sepsis effectively.The exceptional stability and antibacterial efficacy of AgSNP@CD under complex and extreme conditions make it a well-suited dressing strategy for the prevention and treatment of wound infection in emergency.展开更多
In 2024,China’s natural gas industry continues to show a positive trend.In the field of exploration and development,a large ultra-deep water and ultra-shallow gas field has been discovered,further enhancing the uniqu...In 2024,China’s natural gas industry continues to show a positive trend.In the field of exploration and development,a large ultra-deep water and ultra-shallow gas field has been discovered,further enhancing the unique deep-water complex oil and gas exploration and development technology system independently developed by China.Remarkable achievements have been made in offshore development,including the commissioning of Deep Sea No.1 PhaseⅡ,the first deep-water high-pressure gas field.Additionally,the establishment of the Daji gas field,the first onshore coal rock gas field with an oil and gas equivalent of one million tons,provides strong support for domestic natural gas production.In terms of infrastructure construction,the entire China-Russia east-route natural gas pipeline has been completed,the Xinjiang section of the West Fourth Line is now operational,the Southern Xinjiang Gas Pipeline project has been fully launched,and five new or expanded LNG receiving terminals have been added,increasing the annual receiving capacity by 21.10 million tons.In the field of related equipment manufacturing,China successfully delivered the first vessel of its largest LNG transportation ship construction project,the Greenergy Ocean,and successfully launched its first large-scale floating natural gas liquefaction facility,the NGUYA FLNG.In terms of market supply and demand,natural gas consumption exceeded 400 billion m^(3) for the first time,with apparent consumption reaching 412.43 billion m^(3),an increase of 24.9 billion m^(3) year-on-year,reflecting a growth rate of 6.4%.The total supply reached 424.3 billion m^(3),an increase of 27.5 billion m^(3) year-on-year,with a growth rate of 7.5%.In terms of regulatory policy,China has once again issued a natural gas utilization policy aimed at further guiding the orderly and efficient development of the natural gas market.展开更多
On February 20,2025,China National Petroleum Corporation announced that China's first ultra-deep scientific exploration well-Shenditake 1 Well-successfully reached a depth of 10910 m underground(Fig.1).Deep Earth ...On February 20,2025,China National Petroleum Corporation announced that China's first ultra-deep scientific exploration well-Shenditake 1 Well-successfully reached a depth of 10910 m underground(Fig.1).Deep Earth Towerke 1 Well is located in the heart of the Taklamakan Desert in the Xinjiang Uyghur Autonomous Region,within the territory of Shaya County.It has become the deepest vertical well in Asia and the second deepest in the world.The well has successively set five major engineering records:The deepest global tailpipe cementing,the deepest global cable imaging logging,the fastest global onshore drilling to exceed 10000 m,the deepest direct well drilling in Asia,and the deepest onshore coring in Asia.This marks another major breakthrough for China in the field of“Deep Earth”exploration,following its achievements in“Deep Space”and“Deep Sea.”展开更多
The fast growth of mobile autonomous machines from traditional equipment to unmanned autonomous vehicles has fueled the demand for accurate and reliable localization solutions in diverse application domains.Ultra Wide...The fast growth of mobile autonomous machines from traditional equipment to unmanned autonomous vehicles has fueled the demand for accurate and reliable localization solutions in diverse application domains.Ultra Wide Band(UWB)technology has emerged as a promising candidate for addressing this need,offering high precision,immunity to multipath interference,and robust performance in challenging environments.In this comprehensive survey,we systematically explore UWB-based localization for mobile autonomous machines,spanning from fundamental principles to future trends.To the best of our knowledge,this review paper stands as the pioneer in systematically dissecting the algorithms of UWB-based localization for mobile autonomous machines,covering a spectrum from bottom-ranging schemes to advanced sensor fusion,error mitigation,and optimization techniques.By synthesizing existing knowledge,evaluating current methodologies,and highlighting future trends,this review aims to catalyze progress and innovation in the field,unlocking new opportunities for mobile autonomous machine applications across diverse industries and domains.Thus,it serves as a valuable resource for researchers,practitioners,and stakeholders interested in advancing the state-of-the-art UWB-based localization for mobile autonomous machines.展开更多
Low-altitude economy opens up a completely new aerial space for economic growth by enabling brand new services such as fast logistics delivery,timely emergency rescue,and wide-area,high-definition environmental monito...Low-altitude economy opens up a completely new aerial space for economic growth by enabling brand new services such as fast logistics delivery,timely emergency rescue,and wide-area,high-definition environmental monitoring.This new space has many distinct features and therefore faces many new challenges compared with ground-and high-altitude-based information infrastructures.As a result,the rapid and mass development of unmanned aerial vehicles(UAVs)in low-altitude space will inevitably necessitate research on providing ultra-reliable,low-latency,high-capacity.展开更多
Intelligent polymers have garnered significant attention for enhancing component safety,but there are still obstacles to achieving rapid self-healing at room temperature.Here,inspired by the microscopic layered struct...Intelligent polymers have garnered significant attention for enhancing component safety,but there are still obstacles to achieving rapid self-healing at room temperature.Here,inspired by the microscopic layered structure of mother-of-pearl,we have developed a biomimetic composite with high strength and self-repairing capabilities,achieved by the ordered arrangement of pearl-like structures within a flexible polyurethane matrix and GO nanosheets functionalized by in situ polymerization of carbon dots(CDs),this biomimetic interface design approach results in a material strength of 8 MPa and toughness(162 MJ m^(-3)),exceptional ductile properties(2697%elongation at break),and a world-record the fast and high-efficient self-healing ability at room temperature(96%at 25℃for 60 min).Thereby these composites overcome the limitations of dynamic composite networks of graphene that struggle to balance repair capability and robustness,and the CDs in situ loaded in the interfacial layer inhibit corrosion and prevent damage to the metal substrate during the repair process.(TheƵ_(f=0.01Hz)was 1.81×10^(9)Ωcm^(2)after 2 h of healing).Besides,the material can be intelligently actuated and shape memory repaired,which provides reliable protection for developments in smart and flexible devices such as robots and electronic skins.展开更多
Correction to:Rare Met.https://doi.org/10.1007/s12598-021-01815-z In the original publication,Fig.5 was published with few mistakes.The correct version of Fig.5 is given in this correction.
文摘Objective: To observe the effect of electroacupuncture (EA) on learning and memory abilities and ultrastructure of synapses in CA3 region of the hippocampus in vascular dementia (VD) rats. Methods: A total of 32 SD rats were randomized into control (sham-operation, n=7), model (n=7), EA (n=9) and medication (n=9) groups. VD model was established by occlusion of the bilateral vertebral arteries (electrocoagulation) and bilateral common carotid arteries (occlusion for 5 min and reperfusion for 10 min , repeated the procedure for 3 times to induce global ischemia). EA ( 150 Hz , 1 mA ) was applied to “Baihui”(百会 GV 20), “Geshu”(膈俞 BL 17), “Pishu”(脾俞 BL 20) and “Shenshu”(肾俞 BL 23) for 20 min , once daily and continuously for 15 days. In medication group, the rats were fed with Nimotong (12 mg/kg), once daily and continuously for 15 days. Morris water maze method was used to test the animals’ learning and memory abilities (latencies to find the hidden platform determined by place navigation trials, and latencies to cross on the location of the removed platform determined by spatial probe trials) after the treatment. Ultrastructural changes (numerical density, N_A,surface density, Sv and volume density, Vv) of Gray type 1 synapses in CA3 region of the hippocampus were observed by using transmission electronic microscope and automatic image analysis system. Results: 1) Place navigation test showed that in comparison with control group, the average escape latency of VD group was significantly longer (P<0.01), while in comparison with VD group, the latencies of both EA and medication groups decreased significantly (P<0.01). No significant difference was found between EA and medication groups in the escape latency (P>0.05). 2) Spatial probe-test displayed that in comparison with control group, the times which the animals crossed the target platform in VD group decreased significantly (P<0.01), while compared with VD group, those of both EA and medication groups increased considerably (P<0.01). No significant differences were found between EA and medication groups in the times for rats to cross the target quadrant and among the 4 groups in the times for rats to cross the other quadrants. 3) Compared with control group, N_A, Sv, and Vv of VD group decreased significantly (P<0.01), while in comparison with VD group, the 3 indexes of both EA and medication groups increased significantly (P<0.01), no significant differences were found between EA and medication groups in these 3 indexes (P>0.05). Conclusion: EA can restrain the loss of Gray type Ⅰsynapses in CA3 region of the hippocampus to improve learning and memory abilities in VD rats.
文摘It is shoum that the time-dependent intensity of an ultraehort laser puIse can recovered from the second-order correlation G^((2))(τ) and tthe third-order correlation with aingle time-delay G^((3))(τ).The recovery is successfully carnied out by a computer with ingenious progrorming.
基金support from the National Natu-ral Science Foundation of China (Nos.22275081,82372117)China Postdoctoral Science Foundation (2022M711532 and 2022T150302).
文摘The use of antibacterial dressings is crucial in the prevention and treatment of wound infection in emergency sit-uations.However,the efficacy of dressings is compromised by long-term storage or exposure to harsh conditions.Here,an ultrastable in-situ silver nanoparticle dressing(AgSNP@CD)was prepared for effective prevention and treatment of wound infection in emergency.The fabrication process of AgSNP@CD is simple,suitable for large-scale production.Due to the strong interaction between the in-situ synthesized AgNPs and the cotton fabric,AgSNP@CD owned remarkable stability,thus retaining its antimicrobial efficacy even after long-term storage(up to 2 years)and under extreme conditions(damp heat,low temperatures,low-oxygen,water immersion,acid-alkali erosion).Both in vitro and in vivo results demonstrated the extraordinary antibacterial efficacy and stability of AgSNP@CD,facilitating infection prevention and wound healing in extreme conditions.In particular,AgSNP@CD exhibited a superior treatment effect on severe bacteria-infected trauma and can prevent the occur-rence of sepsis effectively.The exceptional stability and antibacterial efficacy of AgSNP@CD under complex and extreme conditions make it a well-suited dressing strategy for the prevention and treatment of wound infection in emergency.
文摘In 2024,China’s natural gas industry continues to show a positive trend.In the field of exploration and development,a large ultra-deep water and ultra-shallow gas field has been discovered,further enhancing the unique deep-water complex oil and gas exploration and development technology system independently developed by China.Remarkable achievements have been made in offshore development,including the commissioning of Deep Sea No.1 PhaseⅡ,the first deep-water high-pressure gas field.Additionally,the establishment of the Daji gas field,the first onshore coal rock gas field with an oil and gas equivalent of one million tons,provides strong support for domestic natural gas production.In terms of infrastructure construction,the entire China-Russia east-route natural gas pipeline has been completed,the Xinjiang section of the West Fourth Line is now operational,the Southern Xinjiang Gas Pipeline project has been fully launched,and five new or expanded LNG receiving terminals have been added,increasing the annual receiving capacity by 21.10 million tons.In the field of related equipment manufacturing,China successfully delivered the first vessel of its largest LNG transportation ship construction project,the Greenergy Ocean,and successfully launched its first large-scale floating natural gas liquefaction facility,the NGUYA FLNG.In terms of market supply and demand,natural gas consumption exceeded 400 billion m^(3) for the first time,with apparent consumption reaching 412.43 billion m^(3),an increase of 24.9 billion m^(3) year-on-year,reflecting a growth rate of 6.4%.The total supply reached 424.3 billion m^(3),an increase of 27.5 billion m^(3) year-on-year,with a growth rate of 7.5%.In terms of regulatory policy,China has once again issued a natural gas utilization policy aimed at further guiding the orderly and efficient development of the natural gas market.
文摘On February 20,2025,China National Petroleum Corporation announced that China's first ultra-deep scientific exploration well-Shenditake 1 Well-successfully reached a depth of 10910 m underground(Fig.1).Deep Earth Towerke 1 Well is located in the heart of the Taklamakan Desert in the Xinjiang Uyghur Autonomous Region,within the territory of Shaya County.It has become the deepest vertical well in Asia and the second deepest in the world.The well has successively set five major engineering records:The deepest global tailpipe cementing,the deepest global cable imaging logging,the fastest global onshore drilling to exceed 10000 m,the deepest direct well drilling in Asia,and the deepest onshore coring in Asia.This marks another major breakthrough for China in the field of“Deep Earth”exploration,following its achievements in“Deep Space”and“Deep Sea.”
文摘The fast growth of mobile autonomous machines from traditional equipment to unmanned autonomous vehicles has fueled the demand for accurate and reliable localization solutions in diverse application domains.Ultra Wide Band(UWB)technology has emerged as a promising candidate for addressing this need,offering high precision,immunity to multipath interference,and robust performance in challenging environments.In this comprehensive survey,we systematically explore UWB-based localization for mobile autonomous machines,spanning from fundamental principles to future trends.To the best of our knowledge,this review paper stands as the pioneer in systematically dissecting the algorithms of UWB-based localization for mobile autonomous machines,covering a spectrum from bottom-ranging schemes to advanced sensor fusion,error mitigation,and optimization techniques.By synthesizing existing knowledge,evaluating current methodologies,and highlighting future trends,this review aims to catalyze progress and innovation in the field,unlocking new opportunities for mobile autonomous machine applications across diverse industries and domains.Thus,it serves as a valuable resource for researchers,practitioners,and stakeholders interested in advancing the state-of-the-art UWB-based localization for mobile autonomous machines.
文摘Low-altitude economy opens up a completely new aerial space for economic growth by enabling brand new services such as fast logistics delivery,timely emergency rescue,and wide-area,high-definition environmental monitoring.This new space has many distinct features and therefore faces many new challenges compared with ground-and high-altitude-based information infrastructures.As a result,the rapid and mass development of unmanned aerial vehicles(UAVs)in low-altitude space will inevitably necessitate research on providing ultra-reliable,low-latency,high-capacity.
基金support of the Jiangsu Provincial Department of Science and Technology Innovation Support Program(No.BK20222004)the National Natural Science Foundation of China(No.52201077).
文摘Intelligent polymers have garnered significant attention for enhancing component safety,but there are still obstacles to achieving rapid self-healing at room temperature.Here,inspired by the microscopic layered structure of mother-of-pearl,we have developed a biomimetic composite with high strength and self-repairing capabilities,achieved by the ordered arrangement of pearl-like structures within a flexible polyurethane matrix and GO nanosheets functionalized by in situ polymerization of carbon dots(CDs),this biomimetic interface design approach results in a material strength of 8 MPa and toughness(162 MJ m^(-3)),exceptional ductile properties(2697%elongation at break),and a world-record the fast and high-efficient self-healing ability at room temperature(96%at 25℃for 60 min).Thereby these composites overcome the limitations of dynamic composite networks of graphene that struggle to balance repair capability and robustness,and the CDs in situ loaded in the interfacial layer inhibit corrosion and prevent damage to the metal substrate during the repair process.(TheƵ_(f=0.01Hz)was 1.81×10^(9)Ωcm^(2)after 2 h of healing).Besides,the material can be intelligently actuated and shape memory repaired,which provides reliable protection for developments in smart and flexible devices such as robots and electronic skins.
文摘Correction to:Rare Met.https://doi.org/10.1007/s12598-021-01815-z In the original publication,Fig.5 was published with few mistakes.The correct version of Fig.5 is given in this correction.
