Presented here is a one-pot strategy starting from rationally designed macrocyclic precursors for the diverse construction of sophisticated ultracycles.The type and amount of the base were found to significantly influ...Presented here is a one-pot strategy starting from rationally designed macrocyclic precursors for the diverse construction of sophisticated ultracycles.The type and amount of the base were found to significantly influence the macrocyclization outcome.The use of 4.0 equiv.CsF resulted in ultracycles of both types A and B while the presence of CsF larger than 6.0 equiv.produced only type B ultracycles.Existence of anion template increased the total yields and affected the distribution of the ultracycles.The ultracycles can accommodate large organic dicarboxylates anions via multiple anion-πand hydrogen bonds,and show selectivity to the size-matched heptanedioate(C7^(2−)).Based on all possible species and relevant equilibrium constants as well as material and charge balances,a numerical iterative algorithm was developed and applied to fit the association constants of B2H with dicarboxylates from glutarate(C5^(2−))to octanedioate(C8^(2−)),which gave association constants up to 10^(3) L/mol.展开更多
基金support from the National Natural Science Foundation of China(Nos.22171271,22022112)Beijing National Laboratory for Molecular Sciences(No.BNLMS-CXXM-202002)。
文摘Presented here is a one-pot strategy starting from rationally designed macrocyclic precursors for the diverse construction of sophisticated ultracycles.The type and amount of the base were found to significantly influence the macrocyclization outcome.The use of 4.0 equiv.CsF resulted in ultracycles of both types A and B while the presence of CsF larger than 6.0 equiv.produced only type B ultracycles.Existence of anion template increased the total yields and affected the distribution of the ultracycles.The ultracycles can accommodate large organic dicarboxylates anions via multiple anion-πand hydrogen bonds,and show selectivity to the size-matched heptanedioate(C7^(2−)).Based on all possible species and relevant equilibrium constants as well as material and charge balances,a numerical iterative algorithm was developed and applied to fit the association constants of B2H with dicarboxylates from glutarate(C5^(2−))to octanedioate(C8^(2−)),which gave association constants up to 10^(3) L/mol.
