Ever since the Bush administration took office, the U. S. national security strategy has given rise to much controversy. Whether the U. S. national security strategy is of unilateralism or multilateralistm is a questi...Ever since the Bush administration took office, the U. S. national security strategy has given rise to much controversy. Whether the U. S. national security strategy is of unilateralism or multilateralistm is a question in dispute. Many people think it is a unilateralist strategy. According to their views, to achieve its own objective, the U. S. administration has rarely considered the interests and feelings of other coun-展开更多
Major-country competition,geopolitical conflict,hegemonism and unilateralism all intensified in 2025.The deficits of peace,development,security and governance all increased.In this increasingly unstable global environ...Major-country competition,geopolitical conflict,hegemonism and unilateralism all intensified in 2025.The deficits of peace,development,security and governance all increased.In this increasingly unstable global environment,China’s aim has been to act as a stabilizing and balancing force,supporting constructive cooperation and shared benefit.展开更多
January 20 marked one year since Donald Trump's returm to the White House.At this time last year,wamings that the U.S.might adopt a more unilateral and confrontational foreign policy,prioritizing its own strategic...January 20 marked one year since Donald Trump's returm to the White House.At this time last year,wamings that the U.S.might adopt a more unilateral and confrontational foreign policy,prioritizing its own strategic interests even at great international cost,would likely have been met with widespread skepticism.展开更多
Ocular biological characteristics and refractive errors in children with unilateral congenital ptosis Yu-Ying Sun,Bing-Ying Lin,Zhen Mao,Xuan-Wei Liang,Cui-Yu Zhang,Dan-Ping Huang,Yao Ni,Zuo-Hong Li Int J Ophthalmol 2...Ocular biological characteristics and refractive errors in children with unilateral congenital ptosis Yu-Ying Sun,Bing-Ying Lin,Zhen Mao,Xuan-Wei Liang,Cui-Yu Zhang,Dan-Ping Huang,Yao Ni,Zuo-Hong Li Int J Ophthalmol 2025;18(4):691-698.DOI:10.18240/ijo.2025.04.16 The author requests to change the authorship and affiliations as follows.展开更多
BRICS and Global South must unite against unilateralism and coercion In the face of US President Donald Trump’s aggressive tariff policies and coercive tactics,the Global South is increasingly choosing resistance ove...BRICS and Global South must unite against unilateralism and coercion In the face of US President Donald Trump’s aggressive tariff policies and coercive tactics,the Global South is increasingly choosing resistance over submission.展开更多
The world is now undergoing profound changes unseen in a century,with unilateralism and protectionism gaining momentum.As the head of the Asia-Pacific Think Tank,I would like to discuss the mission and responsibilitie...The world is now undergoing profound changes unseen in a century,with unilateralism and protectionism gaining momentum.As the head of the Asia-Pacific Think Tank,I would like to discuss the mission and responsibilities of China and ASEAN under the tariff hegemony of the United States.展开更多
China-Africa cooperation sets a benchmark for equitable development in a multipolar world Despite rising unilateralism and protectionism in the West and increasing uncertainties in global trade,China-Africa economic a...China-Africa cooperation sets a benchmark for equitable development in a multipolar world Despite rising unilateralism and protectionism in the West and increasing uncertainties in global trade,China-Africa economic and trade cooperation remains on a fast track,backed by concrete actions towards common modernisation.This collaboration reinforces solidarity across the Global South and contributes to greater stability and confidence in the global multilateral trading system.展开更多
Lumbar interbody fusion is essential for treating degenerative lumbar diseases.The disadvantages of open surgery have led to the evolution of minimally invasive spine surgery,including endoscopic techniques such as un...Lumbar interbody fusion is essential for treating degenerative lumbar diseases.The disadvantages of open surgery have led to the evolution of minimally invasive spine surgery,including endoscopic techniques such as unilateral biportal endoscopy(UBE).Leveraging arthroscopic principles,UBE offers superior visualization and flexibility and expands from decompression to fusion(UBE fusion).However,achieving robust UBE fusion presents challenges,such as suboptimal arthrodesis rates and implant-related complications,requiring more than surgical skill alone.Optimizing UBE fusion critically depends on the effective integration of advanced biomaterials with the surgical technique.This minireview assessed recent advances in UBE,focusing on the development of novel biomaterials,such as functionalized porous,expandable,or double-cage designs,to improve bone regeneration outcomes.These advancements address challenges,like washout of bone graft material and biologics,and utilize growth factors,such as recombinant human bone morphogenetic proteins,while exploring pathway modulation to improve outcomes.We also evaluated clinical optimization strategies involving technical refinements,fluid and hemostasis control,key complication mitigation especially concerning dural tears and hematomas,and technologies such as navigation and robotics.While UBE shows promise particularly for early recovery,its long-term success hinges on these biotechnological advancements.High-quality evidence,especially from randomized controlled trials and longterm studies,is needed to validate integrated strategies and define the optimal role of UBE fusion.展开更多
Unilateral pulmonary artery agenesis(UPAA)is a rare congenital cardiovascular anomaly defined by the complete absence of one pulmonary artery,most often affecting the right side.[1]Although typically identified in chi...Unilateral pulmonary artery agenesis(UPAA)is a rare congenital cardiovascular anomaly defined by the complete absence of one pulmonary artery,most often affecting the right side.[1]Although typically identified in childhood due to symptomatic presentation,certain cases may remain undiagnosed until adulthood,particularly in asymptomatic patients or those with subtle clinical signs.展开更多
Coloboma is due to a defect in the closure of the colobomic cleft generally occurring between the 5th and 7th week of embryonic life. Coloboma can affect the adnexa and/or the eyeball. We report the iconography of two...Coloboma is due to a defect in the closure of the colobomic cleft generally occurring between the 5th and 7th week of embryonic life. Coloboma can affect the adnexa and/or the eyeball. We report the iconography of two cases of ocular colobomas and one case of eyelids coloboma at the IOTA CHU. Case 1: This was a 32-year-old patient who consulted for decreased visual acuity in the left eye. The clinical examination found visual acuity of 10/10 in the right eye and hand movement in the left eye. Biomicroscopic examination revealed an iris and chorioretinal coloboma encompassing the papilla. Case 2: This was a 3-year-old child. Who consulted for eyelid malformation since birth. On ophthalmological examination, there was a bilateral coloboma of the inner half of the upper eyelid, associated with an underlying symblepharon and left eye corneal dystrophy. Our course of action consisted of a release of the symblepharon followed by a blepharoplasty which allowed a good anatomical and functional restitution. Case 3: This was a 15-year-old patient who consulted for bilateral visual acuity loss measured by counting fingers at 1m in the right eye and counting fingers at 3m in the left eye. The biomicroscopic examination found a bilateral papillary coloboma associated with a bilateral progressive cataract, an old detachment of the left retina. The etiological assessment was unremarkable. Conclusion: Coloboma is a congenital condition that can affect all parts of the eye. We reported three cases of colobomas, one palpebral, one iris and chorioretinal, and finally, one papillary associated with other ocular pathologies.展开更多
In an era marked by rising protectionism and geopolitical tensions,the world faces a stark choice:embrace multilateral cooperation or succumb to unilateral hegemony.The United States’punitive tariff policies have exp...In an era marked by rising protectionism and geopolitical tensions,the world faces a stark choice:embrace multilateral cooperation or succumb to unilateral hegemony.The United States’punitive tariff policies have exposed the negative effect of economic coercion and isolation.Meanwhile,China’s commitment to openness,innovation,and shared prosperity offers a contrast,a testament to the enduring vitality of multilateralism and global integration.展开更多
BACKGROUND Unilateral biportal endoscopic(UBE)surgery has developed rapidly during the past decade.Continuous epidural space irrigation is generally considered the principal reason for cerebral complications following...BACKGROUND Unilateral biportal endoscopic(UBE)surgery has developed rapidly during the past decade.Continuous epidural space irrigation is generally considered the principal reason for cerebral complications following UBE surgery.We present a case of mental symptoms during the general anesthesia awakening period due to pneumocephalus.CASE SUMMARY A 70-year-old woman with lumbar disc herniation underwent UBE surgery stably under general anesthesia.Uncontrollable hypertension occurred immediately after transfer to the postoperative care unit,accompanied by increased heart rate and tachypnea.During the recovery process,the patient responded to external stimuli but was confused and unable to complete command actions.Neck stiff-ness and significantly increased muscle strength on the left side indicated the presence of de-cerebrate rigidity.An urgent brain computed tomography scan showed pneumocephalus compressing the brainstem.After receiving analgesia and sedation treatment,the patient was conscious three hours later and recovered rapidly.She was discharged on the fifth postoperative day and followed up for 3 months with no surgical or brain complications.CONCLUSION Cerebral complications emerging during the general anesthesia awakening period following UBE surgery are not entirely due to increased intracranial pressure.Pneumocephalus induced by dural injury may also be a potential cause.展开更多
BACKGROUND This is a retrospective study on endoscopic treatment of cervical spinal radiculopathy(CSR)conducted at a single academic institution.Conventional full-spine endoscopy is performed in a single portal which ...BACKGROUND This is a retrospective study on endoscopic treatment of cervical spinal radiculopathy(CSR)conducted at a single academic institution.Conventional full-spine endoscopy is performed in a single portal which has certain limitations of high technical requirements,steep learning curve,and narrow indications.Although unilateral biportal endoscopy(UBE)technique has a gentle learning curve and is gradually applied to treat CSR,all procedures were performed in the uniportal working channel that potentially increase the surgical risk and time in the treatment of complex cases.It is worthy to delve novel technique for more working channels in the treatment of complex CSR.AIM To propose a hybrid technique(HT)that utilizes spine endoscopy in UBE to treatment of CSR.METHODS A total of 81 patients with single-segment CSR who underwent uniportal endoscopic surgery(UES),UBE,or HT at a single institution between September 2019 and August 2021 were retrospectively studied.Perioperative patient data were compared between the groups.The pre-operative and post-operative images were compared to confirm adequate decompression of the nerve root canal.Patients'visual analogue scale(VAS)scores and neck disability index(NDI)were recorded before surgery,and three days,three months and six months after surgery.RESULTS The UBE and HT groups had a significantly shorter operation duration than the UES group.Data for bleeding and length of hospital stay were significantly higher in the UBE group than in the UES and HT groups.The hospitalization cost was lowest in the UES group and highest in the HT group.Soft tissue edema reaction bands on postoperative day 3 were larger in the UBE and HT groups than in the UES group.Post-operative VAS and NDI scores were significantly lower in all three groups than the pre-operative levels.On post-operative day 3,the VAS score for neck pain was significantly higher in the UBE and HT groups than that in the UES group.However,there were no significant differences in the VAS scores for arm pain or NDI between the three groups.The post-operative 3-month and 6-month neck pain VAS,arm pain VAS,NDI,and modified Macnab success rates did not differ statistically between the three groups.CONCLUSION The HT for CSR treatment has the advantage of double working channels to facilitate decompression and hemostasis,improving the surgical efficiency and clinical outcomes of CSR.展开更多
The Regional Comprehensive Economic Partnership(RCEP)is a significant achievement in terms of Asia’s exploration and efforts toward regional economic integration.It integrates regional economic and trade cooperation ...The Regional Comprehensive Economic Partnership(RCEP)is a significant achievement in terms of Asia’s exploration and efforts toward regional economic integration.It integrates regional economic and trade cooperation mechanisms,demonstrates the determination and capabilities of Asian countries to promote open cooperation.展开更多
Highlights●CRISPR/Cas9 RNP complex-based strategy demonstrates robustness and accuracy in generating gene-edited sheep.●Sheep horn development remains unaffected by partial RXFP2 knockout.●Partial RXFP2 knockout re...Highlights●CRISPR/Cas9 RNP complex-based strategy demonstrates robustness and accuracy in generating gene-edited sheep.●Sheep horn development remains unaffected by partial RXFP2 knockout.●Partial RXFP2 knockout results in unilateral cryptorchidism in sheep.展开更多
The U.S.administration's decision tounilaterally impose sweeping tariff increas-es on tmported goods represents a signifi-cant challenge to the existing global tradingsystem,which has long been structuredaround mu...The U.S.administration's decision tounilaterally impose sweeping tariff increas-es on tmported goods represents a signifi-cant challenge to the existing global tradingsystem,which has long been structuredaround multilateral(WTO),regional,andbilateral(FTA)trade agreements.展开更多
Approximately 5%of patients with renal cancer present with synchronous bilateral renal masses(SBRM).1,2 Bilateral renal tumors associated with hereditary syndromes often exhibit more aggressive biological behaviors co...Approximately 5%of patients with renal cancer present with synchronous bilateral renal masses(SBRM).1,2 Bilateral renal tumors associated with hereditary syndromes often exhibit more aggressive biological behaviors compared to sporadic SBRM cases.3,4 Notably,the prognosis for sporadic cases,in terms of cancerspecific and distant metastasis-free survival,is comparable to that of unilateral renal masses.展开更多
文摘Ever since the Bush administration took office, the U. S. national security strategy has given rise to much controversy. Whether the U. S. national security strategy is of unilateralism or multilateralistm is a question in dispute. Many people think it is a unilateralist strategy. According to their views, to achieve its own objective, the U. S. administration has rarely considered the interests and feelings of other coun-
文摘Major-country competition,geopolitical conflict,hegemonism and unilateralism all intensified in 2025.The deficits of peace,development,security and governance all increased.In this increasingly unstable global environment,China’s aim has been to act as a stabilizing and balancing force,supporting constructive cooperation and shared benefit.
文摘January 20 marked one year since Donald Trump's returm to the White House.At this time last year,wamings that the U.S.might adopt a more unilateral and confrontational foreign policy,prioritizing its own strategic interests even at great international cost,would likely have been met with widespread skepticism.
文摘Ocular biological characteristics and refractive errors in children with unilateral congenital ptosis Yu-Ying Sun,Bing-Ying Lin,Zhen Mao,Xuan-Wei Liang,Cui-Yu Zhang,Dan-Ping Huang,Yao Ni,Zuo-Hong Li Int J Ophthalmol 2025;18(4):691-698.DOI:10.18240/ijo.2025.04.16 The author requests to change the authorship and affiliations as follows.
文摘BRICS and Global South must unite against unilateralism and coercion In the face of US President Donald Trump’s aggressive tariff policies and coercive tactics,the Global South is increasingly choosing resistance over submission.
文摘The world is now undergoing profound changes unseen in a century,with unilateralism and protectionism gaining momentum.As the head of the Asia-Pacific Think Tank,I would like to discuss the mission and responsibilities of China and ASEAN under the tariff hegemony of the United States.
文摘China-Africa cooperation sets a benchmark for equitable development in a multipolar world Despite rising unilateralism and protectionism in the West and increasing uncertainties in global trade,China-Africa economic and trade cooperation remains on a fast track,backed by concrete actions towards common modernisation.This collaboration reinforces solidarity across the Global South and contributes to greater stability and confidence in the global multilateral trading system.
基金Supported by Joint Traditional Chinese Medicine Science and Technology Projects of National Demonstration Zones for Comprehensive Traditional Chinese Medicine,No.GZY-KJS-SD-2023-031.
文摘Lumbar interbody fusion is essential for treating degenerative lumbar diseases.The disadvantages of open surgery have led to the evolution of minimally invasive spine surgery,including endoscopic techniques such as unilateral biportal endoscopy(UBE).Leveraging arthroscopic principles,UBE offers superior visualization and flexibility and expands from decompression to fusion(UBE fusion).However,achieving robust UBE fusion presents challenges,such as suboptimal arthrodesis rates and implant-related complications,requiring more than surgical skill alone.Optimizing UBE fusion critically depends on the effective integration of advanced biomaterials with the surgical technique.This minireview assessed recent advances in UBE,focusing on the development of novel biomaterials,such as functionalized porous,expandable,or double-cage designs,to improve bone regeneration outcomes.These advancements address challenges,like washout of bone graft material and biologics,and utilize growth factors,such as recombinant human bone morphogenetic proteins,while exploring pathway modulation to improve outcomes.We also evaluated clinical optimization strategies involving technical refinements,fluid and hemostasis control,key complication mitigation especially concerning dural tears and hematomas,and technologies such as navigation and robotics.While UBE shows promise particularly for early recovery,its long-term success hinges on these biotechnological advancements.High-quality evidence,especially from randomized controlled trials and longterm studies,is needed to validate integrated strategies and define the optimal role of UBE fusion.
文摘Unilateral pulmonary artery agenesis(UPAA)is a rare congenital cardiovascular anomaly defined by the complete absence of one pulmonary artery,most often affecting the right side.[1]Although typically identified in childhood due to symptomatic presentation,certain cases may remain undiagnosed until adulthood,particularly in asymptomatic patients or those with subtle clinical signs.
文摘Coloboma is due to a defect in the closure of the colobomic cleft generally occurring between the 5th and 7th week of embryonic life. Coloboma can affect the adnexa and/or the eyeball. We report the iconography of two cases of ocular colobomas and one case of eyelids coloboma at the IOTA CHU. Case 1: This was a 32-year-old patient who consulted for decreased visual acuity in the left eye. The clinical examination found visual acuity of 10/10 in the right eye and hand movement in the left eye. Biomicroscopic examination revealed an iris and chorioretinal coloboma encompassing the papilla. Case 2: This was a 3-year-old child. Who consulted for eyelid malformation since birth. On ophthalmological examination, there was a bilateral coloboma of the inner half of the upper eyelid, associated with an underlying symblepharon and left eye corneal dystrophy. Our course of action consisted of a release of the symblepharon followed by a blepharoplasty which allowed a good anatomical and functional restitution. Case 3: This was a 15-year-old patient who consulted for bilateral visual acuity loss measured by counting fingers at 1m in the right eye and counting fingers at 3m in the left eye. The biomicroscopic examination found a bilateral papillary coloboma associated with a bilateral progressive cataract, an old detachment of the left retina. The etiological assessment was unremarkable. Conclusion: Coloboma is a congenital condition that can affect all parts of the eye. We reported three cases of colobomas, one palpebral, one iris and chorioretinal, and finally, one papillary associated with other ocular pathologies.
文摘In an era marked by rising protectionism and geopolitical tensions,the world faces a stark choice:embrace multilateral cooperation or succumb to unilateral hegemony.The United States’punitive tariff policies have exposed the negative effect of economic coercion and isolation.Meanwhile,China’s commitment to openness,innovation,and shared prosperity offers a contrast,a testament to the enduring vitality of multilateralism and global integration.
文摘BACKGROUND Unilateral biportal endoscopic(UBE)surgery has developed rapidly during the past decade.Continuous epidural space irrigation is generally considered the principal reason for cerebral complications following UBE surgery.We present a case of mental symptoms during the general anesthesia awakening period due to pneumocephalus.CASE SUMMARY A 70-year-old woman with lumbar disc herniation underwent UBE surgery stably under general anesthesia.Uncontrollable hypertension occurred immediately after transfer to the postoperative care unit,accompanied by increased heart rate and tachypnea.During the recovery process,the patient responded to external stimuli but was confused and unable to complete command actions.Neck stiff-ness and significantly increased muscle strength on the left side indicated the presence of de-cerebrate rigidity.An urgent brain computed tomography scan showed pneumocephalus compressing the brainstem.After receiving analgesia and sedation treatment,the patient was conscious three hours later and recovered rapidly.She was discharged on the fifth postoperative day and followed up for 3 months with no surgical or brain complications.CONCLUSION Cerebral complications emerging during the general anesthesia awakening period following UBE surgery are not entirely due to increased intracranial pressure.Pneumocephalus induced by dural injury may also be a potential cause.
基金Supported by the Provincial Natural Science Foundation of Gansu,No.24JRRF008Science and Technology Research Project of Songjiang District,No.2024SJKJGG105+1 种基金National Natural Science Foundation of China,No.82202694Clinical Research Innovation Plan of Shanghai General Hospital,No.CTCCR-2021C10.
文摘BACKGROUND This is a retrospective study on endoscopic treatment of cervical spinal radiculopathy(CSR)conducted at a single academic institution.Conventional full-spine endoscopy is performed in a single portal which has certain limitations of high technical requirements,steep learning curve,and narrow indications.Although unilateral biportal endoscopy(UBE)technique has a gentle learning curve and is gradually applied to treat CSR,all procedures were performed in the uniportal working channel that potentially increase the surgical risk and time in the treatment of complex cases.It is worthy to delve novel technique for more working channels in the treatment of complex CSR.AIM To propose a hybrid technique(HT)that utilizes spine endoscopy in UBE to treatment of CSR.METHODS A total of 81 patients with single-segment CSR who underwent uniportal endoscopic surgery(UES),UBE,or HT at a single institution between September 2019 and August 2021 were retrospectively studied.Perioperative patient data were compared between the groups.The pre-operative and post-operative images were compared to confirm adequate decompression of the nerve root canal.Patients'visual analogue scale(VAS)scores and neck disability index(NDI)were recorded before surgery,and three days,three months and six months after surgery.RESULTS The UBE and HT groups had a significantly shorter operation duration than the UES group.Data for bleeding and length of hospital stay were significantly higher in the UBE group than in the UES and HT groups.The hospitalization cost was lowest in the UES group and highest in the HT group.Soft tissue edema reaction bands on postoperative day 3 were larger in the UBE and HT groups than in the UES group.Post-operative VAS and NDI scores were significantly lower in all three groups than the pre-operative levels.On post-operative day 3,the VAS score for neck pain was significantly higher in the UBE and HT groups than that in the UES group.However,there were no significant differences in the VAS scores for arm pain or NDI between the three groups.The post-operative 3-month and 6-month neck pain VAS,arm pain VAS,NDI,and modified Macnab success rates did not differ statistically between the three groups.CONCLUSION The HT for CSR treatment has the advantage of double working channels to facilitate decompression and hemostasis,improving the surgical efficiency and clinical outcomes of CSR.
文摘The Regional Comprehensive Economic Partnership(RCEP)is a significant achievement in terms of Asia’s exploration and efforts toward regional economic integration.It integrates regional economic and trade cooperation mechanisms,demonstrates the determination and capabilities of Asian countries to promote open cooperation.
基金supported by the National Key Research and Development Program of China(2022YFD1300200)the National Natural Science Foundation of China(32161143010,32202646,and 32272848)+2 种基金the China Agriculture Research System(CARS-39)the Key Special Project of Ningxia Science and Technology Department,China(2021BEF02024)the local grants,China(NXTS2021-001,2022GD-TSLD-46,NK2022010207,and NXTS2022-001)。
文摘Highlights●CRISPR/Cas9 RNP complex-based strategy demonstrates robustness and accuracy in generating gene-edited sheep.●Sheep horn development remains unaffected by partial RXFP2 knockout.●Partial RXFP2 knockout results in unilateral cryptorchidism in sheep.
文摘The U.S.administration's decision tounilaterally impose sweeping tariff increas-es on tmported goods represents a signifi-cant challenge to the existing global tradingsystem,which has long been structuredaround multilateral(WTO),regional,andbilateral(FTA)trade agreements.
文摘Approximately 5%of patients with renal cancer present with synchronous bilateral renal masses(SBRM).1,2 Bilateral renal tumors associated with hereditary syndromes often exhibit more aggressive biological behaviors compared to sporadic SBRM cases.3,4 Notably,the prognosis for sporadic cases,in terms of cancerspecific and distant metastasis-free survival,is comparable to that of unilateral renal masses.
