Gandou decoction(GDD),a well-known traditional Chinese medicine(TCM)formula,has been widely used for decades to treat Wilson's disease(WD)in China due to its remarkable clinical effects.However,the chemical consti...Gandou decoction(GDD),a well-known traditional Chinese medicine(TCM)formula,has been widely used for decades to treat Wilson's disease(WD)in China due to its remarkable clinical effects.However,the chemical constituents of GDD still remain unclear because of their complexity.In this work,a reliable and sensitive strategy based on ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry(UPLC-Q-TOF-MSE)and UNIFI informatics platform was applied to investigate the chemical components in GDD.In total,96 compounds including anthraquinones,alkaloids,protostane triterpenoids,flavonoids,triterpenoid saponins,tannins,curcuminoids,etc,were identified or tentatively characterized from GDD by comparing their retention time,accurate mass within 5 ppm error and MSE fragmentation patterns.Among them,eleven compounds were confirmed unambiguously with reference standards.Representative compounds in different chemical structure types were analyzed in fragmentation patterns and characteristic ions.Moreover,to better understand the chemical contribution of individual herbs to the whole decoction,the corresponding each herb in GDD was also detected.This study developed a rapid method for characterizing the chemical constituents in GDD,which could not only be used for chemical standardization and quality control,but also be helpful for further research of GDD in vivo.展开更多
Traditional Chinese Medicine(TCM)has been used in prevention and treatment of disease in clinical practice for thousands of years,with an indispensable role of multiple ingredients.Thus,a rapid and effective chemical ...Traditional Chinese Medicine(TCM)has been used in prevention and treatment of disease in clinical practice for thousands of years,with an indispensable role of multiple ingredients.Thus,a rapid and effective chemical ingredients analysis was of necessary to be established for the evaluation of the holistic quality of TCM.As could afford the data with high resolution and high sensitivity,展开更多
1 Development Trend ofIntelligent ServicesServices on traditional Intelligent Networks(IN)are created by Service CreationEnvironment Point(SCEP),and uploadedonline to Service Control Point(SCP)to runvia Service Manage...1 Development Trend ofIntelligent ServicesServices on traditional Intelligent Networks(IN)are created by Service CreationEnvironment Point(SCEP),and uploadedonline to Service Control Point(SCP)to runvia Service Management Access Point(SMAP)and Service Management Point(SMP).INsavailable can meet most demands of value-added voice services.But IN is not a completelyopen network.It is very difficult to create serviceson it by SCEP.Due to the fact that SCEP has not beendefined with a unified service file format yet,unified service models are generally provided bySCP equipment providers,not by operators or展开更多
Inheriting all the advantages of Intelligent Network (IN), ZTE's Unified Service Platform has unique features. By separating billing functionality from Service Control Point(SCP) and adopting Diameter protocol to ...Inheriting all the advantages of Intelligent Network (IN), ZTE's Unified Service Platform has unique features. By separating billing functionality from Service Control Point(SCP) and adopting Diameter protocol to connect the external billing unit, it has much more freedom to perform pre-paid and post-paid services convergence. The platform is a truly open system with Parlay/Open Service Architecture (Parlay/OSA) standards followed, and able to open Application Programming Interfaces (API) to the third parties for service development. ZTE's unified service platform, a leading IN into the future, is a good choice for network operators.展开更多
ZTE Corporation (ZTE),a leading global provider of telecommunications equipment and network solutions,on February 12,2009,released a unique Unified Open Environment (UOE) platform that will make it easier fortelecom o...ZTE Corporation (ZTE),a leading global provider of telecommunications equipment and network solutions,on February 12,2009,released a unique Unified Open Environment (UOE) platform that will make it easier fortelecom operators展开更多
Mobile medical service has become an indispensable method for the hospitals to improve service quality, while mobile payment has provided an effective solution for solving the problems of long queuing, long examinatio...Mobile medical service has become an indispensable method for the hospitals to improve service quality, while mobile payment has provided an effective solution for solving the problems of long queuing, long examination time, long waiting before being hospitalized and short time of diagnosis and treatment of the traditional outpatient services. With the increasing diversification of payment methods, it is necessary for the hospitals to establish a unified payment platform in order to support different business scenarios according to needs and standardize the interfaces of various developers and manufacturers. In addition, it will help the Financial Department timely identify the problems in the tons of transaction data and better serve the goals of the hospitals to streamline the procedures of medical services and achieve concentrated information management.展开更多
The content security requirements of a radio frequency identification （RFID） based logistics-customs clearance service platform （LCCSP） are analysed in this paper. Then, both the unified identity authentication an...The content security requirements of a radio frequency identification （RFID） based logistics-customs clearance service platform （LCCSP） are analysed in this paper. Then, both the unified identity authentication and the access control modules are designed according to those analyses. Finally, the unified identity authentication and the access control on the business level are implemented separately. In the unified identity authentication module, based on an improved Kerberos-based authentication approach, a new control transfer method is proposed to solve the sharing problem of tickets among different servers of different departments. In the access control module, the functions of access controls are divided into different granularities to make the access control management more flexible. Moreover, the access control module has significant reference value for user management in similar systems.展开更多
基金This research was supported by the National Natural Science Foundation of China(No:81872976,81873038,81303245)Key Project of the National Science Fund of Anhui Province(No:KJ2016A398)+1 种基金Key Project Foundation of Oversea Visiting and Research for the Excellent Young and Middle-aged Faculties in Universities of Anhui Province(No:gxgwfx2018042)Primary Research&Development Plan of Anhui Province(No:201904a07020051).
文摘Gandou decoction(GDD),a well-known traditional Chinese medicine(TCM)formula,has been widely used for decades to treat Wilson's disease(WD)in China due to its remarkable clinical effects.However,the chemical constituents of GDD still remain unclear because of their complexity.In this work,a reliable and sensitive strategy based on ultra-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry(UPLC-Q-TOF-MSE)and UNIFI informatics platform was applied to investigate the chemical components in GDD.In total,96 compounds including anthraquinones,alkaloids,protostane triterpenoids,flavonoids,triterpenoid saponins,tannins,curcuminoids,etc,were identified or tentatively characterized from GDD by comparing their retention time,accurate mass within 5 ppm error and MSE fragmentation patterns.Among them,eleven compounds were confirmed unambiguously with reference standards.Representative compounds in different chemical structure types were analyzed in fragmentation patterns and characteristic ions.Moreover,to better understand the chemical contribution of individual herbs to the whole decoction,the corresponding each herb in GDD was also detected.This study developed a rapid method for characterizing the chemical constituents in GDD,which could not only be used for chemical standardization and quality control,but also be helpful for further research of GDD in vivo.
文摘Traditional Chinese Medicine(TCM)has been used in prevention and treatment of disease in clinical practice for thousands of years,with an indispensable role of multiple ingredients.Thus,a rapid and effective chemical ingredients analysis was of necessary to be established for the evaluation of the holistic quality of TCM.As could afford the data with high resolution and high sensitivity,
文摘1 Development Trend ofIntelligent ServicesServices on traditional Intelligent Networks(IN)are created by Service CreationEnvironment Point(SCEP),and uploadedonline to Service Control Point(SCP)to runvia Service Management Access Point(SMAP)and Service Management Point(SMP).INsavailable can meet most demands of value-added voice services.But IN is not a completelyopen network.It is very difficult to create serviceson it by SCEP.Due to the fact that SCEP has not beendefined with a unified service file format yet,unified service models are generally provided bySCP equipment providers,not by operators or
文摘Inheriting all the advantages of Intelligent Network (IN), ZTE's Unified Service Platform has unique features. By separating billing functionality from Service Control Point(SCP) and adopting Diameter protocol to connect the external billing unit, it has much more freedom to perform pre-paid and post-paid services convergence. The platform is a truly open system with Parlay/Open Service Architecture (Parlay/OSA) standards followed, and able to open Application Programming Interfaces (API) to the third parties for service development. ZTE's unified service platform, a leading IN into the future, is a good choice for network operators.
文摘ZTE Corporation (ZTE),a leading global provider of telecommunications equipment and network solutions,on February 12,2009,released a unique Unified Open Environment (UOE) platform that will make it easier fortelecom operators
文摘Mobile medical service has become an indispensable method for the hospitals to improve service quality, while mobile payment has provided an effective solution for solving the problems of long queuing, long examination time, long waiting before being hospitalized and short time of diagnosis and treatment of the traditional outpatient services. With the increasing diversification of payment methods, it is necessary for the hospitals to establish a unified payment platform in order to support different business scenarios according to needs and standardize the interfaces of various developers and manufacturers. In addition, it will help the Financial Department timely identify the problems in the tons of transaction data and better serve the goals of the hospitals to streamline the procedures of medical services and achieve concentrated information management.
基金supported by Department of Science & Technology of Guangdong Province (No.2006A15006003)National High Technology Research and Development Program of China (863 Program)(No.2006AA04A120)
文摘The content security requirements of a radio frequency identification （RFID） based logistics-customs clearance service platform （LCCSP） are analysed in this paper. Then, both the unified identity authentication and the access control modules are designed according to those analyses. Finally, the unified identity authentication and the access control on the business level are implemented separately. In the unified identity authentication module, based on an improved Kerberos-based authentication approach, a new control transfer method is proposed to solve the sharing problem of tickets among different servers of different departments. In the access control module, the functions of access controls are divided into different granularities to make the access control management more flexible. Moreover, the access control module has significant reference value for user management in similar systems.
