期刊文献+
共找到2,522篇文章
< 1 2 127 >
每页显示 20 50 100
Review of Artificial Intelligence for Oil and Gas Exploration: Convolutional Neural Network Approaches and the U-Net 3D Model
1
作者 Weiyan Liu 《Open Journal of Geology》 CAS 2024年第4期578-593,共16页
Deep learning, especially through convolutional neural networks (CNN) such as the U-Net 3D model, has revolutionized fault identification from seismic data, representing a significant leap over traditional methods. Ou... Deep learning, especially through convolutional neural networks (CNN) such as the U-Net 3D model, has revolutionized fault identification from seismic data, representing a significant leap over traditional methods. Our review traces the evolution of CNN, emphasizing the adaptation and capabilities of the U-Net 3D model in automating seismic fault delineation with unprecedented accuracy. We find: 1) The transition from basic neural networks to sophisticated CNN has enabled remarkable advancements in image recognition, which are directly applicable to analyzing seismic data. The U-Net 3D model, with its innovative architecture, exemplifies this progress by providing a method for detailed and accurate fault detection with reduced manual interpretation bias. 2) The U-Net 3D model has demonstrated its superiority over traditional fault identification methods in several key areas: it has enhanced interpretation accuracy, increased operational efficiency, and reduced the subjectivity of manual methods. 3) Despite these achievements, challenges such as the need for effective data preprocessing, acquisition of high-quality annotated datasets, and achieving model generalization across different geological conditions remain. Future research should therefore focus on developing more complex network architectures and innovative training strategies to refine fault identification performance further. Our findings confirm the transformative potential of deep learning, particularly CNN like the U-Net 3D model, in geosciences, advocating for its broader integration to revolutionize geological exploration and seismic analysis. 展开更多
关键词 deep Learning Convolutional Neural Networks (CNN) Seismic Fault Identification u-net 3d model Geological Exploration
在线阅读 下载PDF
Advanced Brain Tumor Segmentation in Magnetic Resonance Imaging via 3D U-Net and Generalized Gaussian Mixture Model-Based Preprocessing
2
作者 Khalil Ibrahim Lairedj Zouaoui Chama +5 位作者 Amina Bagdaoui Samia Larguech Younes Menni Nidhal Becheikh Lioua Kolsi Badr M.Alshammari 《Computer Modeling in Engineering & Sciences》 2025年第8期2419-2443,共25页
Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised m... Brain tumor segmentation from Magnetic Resonance Imaging(MRI)supports neurologists and radiologists in analyzing tumors and developing personalized treatment plans,making it a crucial yet challenging task.Supervised models such as 3D U-Net perform well in this domain,but their accuracy significantly improves with appropriate preprocessing.This paper demonstrates the effectiveness of preprocessing in brain tumor segmentation by applying a pre-segmentation step based on the Generalized Gaussian Mixture Model(GGMM)to T1 contrastenhanced MRI scans from the BraTS 2020 dataset.The Expectation-Maximization(EM)algorithm is employed to estimate parameters for four tissue classes,generating a new pre-segmented channel that enhances the training and performance of the 3DU-Net model.The proposed GGMM+3D U-Net framework achieved a Dice coefficient of 0.88 for whole tumor segmentation,outperforming both the standard multiscale 3D U-Net(0.84)and MMU-Net(0.85).It also delivered higher Intersection over Union(IoU)scores compared to models trained without preprocessing or with simpler GMM-based segmentation.These results,supported by qualitative visualizations,suggest that GGMM-based preprocessing should be integrated into brain tumor segmentation pipelines to optimize performance. 展开更多
关键词 Magnetic resonance imaging(MRI) imaging technology GGMM EM algorithm 3d u-net SEGMENTATION
在线阅读 下载PDF
Predicting Marine Heatwaves in the South China Sea Using a 3D U-Net Model Based on Intraseasonal Oscillation Signals from Atmosphere-Ocean Data
3
作者 WANG Lin-hai YU Wei-dong 《Journal of Tropical Meteorology》 2025年第5期478-496,共19页
With the intensification of global warming,marine heatwaves(MHWs)have emerged as a significant extreme hazard,garnering widespread attention and creating a pressing need for accurate prediction.The development of arti... With the intensification of global warming,marine heatwaves(MHWs)have emerged as a significant extreme hazard,garnering widespread attention and creating a pressing need for accurate prediction.The development of artificial intelligence,particularly the application of deep learning to sea surface temperature(SST),has significantly improved the feasibility of predictions.This study utilizes SST and Outgoing Longwave Radiation(OLR)data to train a 3D U-Net model for predicting MHWs in the South China Sea(SCS)with lead times ranging from 1 to 7 days,based on the characteristics of intraseasonal weather processes.Analysis of MHWs occurrences from 1982 to 2023 reveals distinct seasonal patterns,with summer MHWs primarily concentrated in the northern and central SCS,and the highest temperature centers located in the Gulf of Tonkin and west of the Philippines.The 2023 MHW forecast results demonstrate that the 3D U-Net model achieves low error rates and high correlation coefficients with observational data.Incorporating OLR data enhances forecast accuracy compared to SST-only inputs,and training the model exclusively with summer data further improves prediction accuracy.These findings indicate that the proposed method can significantly enhance the accuracy of MHW forecasts. 展开更多
关键词 marine heatwaves Boreal Summer Intra-seasonal Oscillation 3d u-net South China Sea
在线阅读 下载PDF
Building the 3D seismic fault models for the 2021 M_(S)6.4 Yunnan Yangbi earthquake:The potential role of pre-existing faults in generating unexpected moderate-strong earthquakes in southeast Xizang 被引量:1
4
作者 Xiao Sun Jinyu Zhang +4 位作者 Renqi Lu Wei Wang Peng Su Guanshen Liu Fang Xu 《Earthquake Science》 2025年第3期172-186,共15页
The three-dimensional(3D)geometry of a fault is a critical control on earthquake nucleation,dynamic rupture,stress triggering,and related seismic hazards.Therefore,a 3D model of an active fault can significantly impro... The three-dimensional(3D)geometry of a fault is a critical control on earthquake nucleation,dynamic rupture,stress triggering,and related seismic hazards.Therefore,a 3D model of an active fault can significantly improve our understanding of seismogenesis and our ability to evaluate seismic hazards.Utilising the SKUA GoCAD software,we constructed detailed seismic fault models for the 2021 M_(S)6.4 Yangbi earthquake in Yunnan,China,using two sets of relocated earthquake catalogs and focal mechanism solutions following a convenient 3D fault modeling workflow.Our analysis revealed a NW-striking main fault with a high-angle SW dip,accompanied by two branch faults.Interpretation of one dataset revealed a single NNW-striking branch fault SW of the main fault,whereas the other dataset indicated four steep NNE-striking segments with a left-echelon pattern.Additionally,a third ENE-striking short fault was identified NE of the main fault.In combination with the spatial distribution of pre-existing faults,our 3D fault models indicate that the Yangbi earthquake reactivated pre-existing NW-and NE-striking fault directions rather than the surface-exposed Weixi-Qiaohou-Weishan Fault zone.The occurrence of the Yangbi earthquake demonstrates that the reactivation of pre-existing faults away from active fault zones,through either cascade or conjugate rupture modes,can cause unexpected moderate-large earthquakes and severe disasters,necessitating attention in regions like southeast Xizang,which have complex fault systems. 展开更多
关键词 Yangbi earthquake 3d seismogenic fault model relocated earthquakes Weixi-Qiaohou-Weishan fault seismic hazard
在线阅读 下载PDF
Adaptive subtraction with 3D U-net and 3D data windows to suppress seismic multiples
5
作者 Jin-Qiang Huang Li-Yun Fu +3 位作者 Jia-Hui Ma Xing-Zhong Du Zhong-Xiao Li Ke-Yi Sun 《Petroleum Science》 2025年第3期1125-1139,共15页
The deep convolutional neural network U-net has been introduced into adaptive subtraction, which is a critical step in effectively suppressing seismic multiples. The U-net approach has higher precision than the tradit... The deep convolutional neural network U-net has been introduced into adaptive subtraction, which is a critical step in effectively suppressing seismic multiples. The U-net approach has higher precision than the traditional linear regression approach. However, the existing 2D U-net approach with 2D data windows can not deal with elaborate discrepancies between the actual and simulated multiples along the gather direction. It may lead to erroneous preservation of primaries or generate obvious vestigial multiples, especially in complex media. To further enhance the multiple suppression accuracy, we present an adaptive subtraction approach utilizing 3D U-net architecture, which can adaptively separate primaries and multiples utilizing 3D windows. The utilization of 3D windows allows for enhanced depiction of spatial continuity and anisotropy of seismic events along the gather direction in comparison to 2D windows. The 3D U-net approach with 3D windows can more effectively preserve the continuity of primaries and manage the complex disparities between the actual and simulated multiples. The proposed 3D U-net approach exhibits 1 dB improvement in the signal-to-noise ratio compared to the 2D U-net approach, as observed in the synthesis data section, and exhibits more outstanding performance in the preservation of primaries and removal of residual multiples in both synthesis and reality data sections. Moreover, to expedite network training in our proposed 3D U-net approach we employ the transfer learning (TL) strategy by utilizing the network parameters of 3D U-net estimated in the preceding data segment as the initial network parameters of 3D U-net for the subsequent data segment. In the reality data section, the 3D U-net approach incorporating TL reduces the computational expense by 70% compared to the one without TL. 展开更多
关键词 Adaptive subtraction 3d u-net 3d data windows Transfer learning Multiple suppression
原文传递
From Traditional Methods to 3D U-Net: A Comprehensive Review of Brain Tumour Segmentation Techniques
6
作者 Mushtaq Mahyoob Saleh Musab Elkheir Salih +1 位作者 Mohamed A. A. Ahmed Altahir Mohamed Hussein 《Journal of Biomedical Science and Engineering》 2025年第1期1-32,共32页
Accurate brain tumour segmentation is critical for diagnosis and treatment planning, yet challenging due to tumour complexity. Manual segmentation is time-consuming and variable, necessitating automated methods. Deep ... Accurate brain tumour segmentation is critical for diagnosis and treatment planning, yet challenging due to tumour complexity. Manual segmentation is time-consuming and variable, necessitating automated methods. Deep learning, particularly 3D U-Net architectures, has revolutionised medical image analysis by leveraging volumetric data to capture spatial context, enhancing segmentation accuracy. This paper reviews brain tumour segmentation methods, emphasising 3D U-Net advancements. We analyse contributions from the Brain Tumour Segmentation (BraTS) challenges (2014-2023), highlighting key improvements and persistent challenges, including tumour heterogeneity, limited annotated data, varied imaging protocols, computational constraints, and model generalisation. Unlike previous reviews, we synthesise these challenges, proposing targeted research directions: enhancing model robustness through domain adaptation and multi-institutional data sharing, developing lightweight architectures for clinical deployment, integrating multi-modal and clinical data, and incorporating explainability techniques to build clinician trust. By addressing these challenges, we aim to guide future research toward developing more robust, generalisable, and clinically applicable segmentation models, ultimately improving patient outcomes in neuro-oncology. 展开更多
关键词 Brain Tumour MRI Modalities deep Learning 3d u-net BraTS
暂未订购
3D Computational Modeling and Stability Analysis of Highway Slope:A Case Study from the X104 Section in Ganxian County
7
作者 Fujie Dai Yiwen Jin +1 位作者 Yongliang Wang Jiajun Li 《Journal of Electronic Research and Application》 2025年第2期65-68,共4页
Highway planning requires geological surveys and stability analysis of the surrounding area.In the early stage of the survey,the modeling and stability analysis of the survey area can be carried out by using GIS softw... Highway planning requires geological surveys and stability analysis of the surrounding area.In the early stage of the survey,the modeling and stability analysis of the survey area can be carried out by using GIS software to intuitively understand the topography of the study area.The use of DEM to extract terrain factors can be used for simple stability analysis and the source data is easy to obtain,simple to operate,fast to analyze,and reliable analysis results.In this paper,taking the X104 road section in Ganxian County as an example,the ArcGIS platform is used to carry out 3D modeling visualization and stability analysis,and the stability evaluation map of the study area is obtained. 展开更多
关键词 3d modeling STABILITY GIS Highway planning
在线阅读 下载PDF
Exploring 3D Model Rendering Techniques for Cultural Relics Based on 3D Gaussian Splatting
8
作者 Keran Yu 《Journal of Electronic Research and Application》 2025年第5期54-60,共7页
With the widespread application of 3D visualization in digital exhibition halls and virtual reality,achieving efficient rendering and high-fidelity presentation has become a key challenge.This study proposes a hybrid ... With the widespread application of 3D visualization in digital exhibition halls and virtual reality,achieving efficient rendering and high-fidelity presentation has become a key challenge.This study proposes a hybrid point cloud generation method that combines traditional sampling with 3D Gaussian splatting,aiming to address the issues of rendering delay and missing details in existing 3D displays.By improving the OBJ model parsing process and incorporating an adaptive area-weighted sampling algorithm,we achieve adaptive point cloud generation based on triangle density.Innovatively,we advance the ellipsoidal parameter estimation process of 3D Gaussian splatting to the point cloud generation stage.By establishing a mathematical relationship between the covariance matrix and local curvature,the generated point cloud naturally exhibits Gaussian distribution characteristics.Experimental results show that,compared to traditional methods,our approach reduces point cloud data by 38% while maintaining equivalent visual quality at a 4096×4096 texture resolution.By introducing mipmap texture optimization strategies and a GPU-accelerated rasterization pipeline,stable rendering at 60 frames per second is achieved in a WebGL environment.Additionally,we quantize and compress the spherical harmonic function parameters specific to 3D Gaussian splatting,reducing network transmission bandwidth to 52% of the original data.This study provides a new technical pathway for fields requiring high-precision display,such as the digitization of cultural heritage. 展开更多
关键词 3d model dense point cloud 3d Gaussian splatting
在线阅读 下载PDF
Innovative 3D microfluidic intestinal organoid model for assessing cadmium bioavailability in food:implications for enhanced exposure risk assessment
9
作者 Yan Li Wen Sun +6 位作者 Qiao Wang Wan Shi Yu Chen Zhiyong Gong Xiao Guo Xin Liu Yongning Wu 《Food Science and Human Wellness》 2025年第5期1687-1696,共10页
Given the severe toxicity and widespread presence of cadmium(Cd)in staple foods such as rice,accurate dietary exposure assessments are imperative for public health.In vitro bioavailability is commonly used to adjust d... Given the severe toxicity and widespread presence of cadmium(Cd)in staple foods such as rice,accurate dietary exposure assessments are imperative for public health.In vitro bioavailability is commonly used to adjust dietary exposure levels of risk factors;however,traditional planar Transwell models have limitations,such as cell dedifferentiation and lack of key intestinal components,necessitating a more physiologically relevant in vitro platform.This study introduces an innovative three-dimensional(3D)intestinal organoid model using a microfluidic chip to evaluate Cd bioavailability in food.Caco-2 cells were cultured on the chip to mimic small intestinal villi's 3D structure,mucus production,and absorption functions.The model's physiological relevance was thoroughly characterized,demonstrating the formation of a confluent epithelial monolayer with well-developed tight junctions(ZO-1),high microvilli density(F-actin),and significant mucus secretion(Alcian blue staining),closely resembling the physiological intestinal epithelium.Fluorescent particle tracking confirmed its ability to simulate intestinal transport and diffusion.The Cd bioavailability in rice measured by the 3D intestinal organoid model((9.07±0.21)%)was comparable to the mouse model((12.82±3.42)%)but significantly lower than the Caco-2 monolayer model((26.97±1.11)%).This 3D intestinal organoid model provides a novel and reliable strategy for in vitro assessment of heavy metal bioavailability in food,with important implications for food safety and risk assessment. 展开更多
关键词 Planar Transwell model 3d intestinal organoid model Physiological relevance Cd bioavailability
在线阅读 下载PDF
Vector Extraction from Design Drawings for Intelligent 3D Modeling of Transmission Towers
10
作者 Ziqiang Tang Chao Han +5 位作者 Hongwu Li Zhou Fan Ke Sun Yuntian Huang Yuhang Chen Chenxing Wang 《Computers, Materials & Continua》 2025年第2期2813-2829,共17页
Accurate vector extraction from design drawings is required first to automatically create 3D models from pixel-level engineering design drawings. However, this task faces the challenges of complicated design shapes as... Accurate vector extraction from design drawings is required first to automatically create 3D models from pixel-level engineering design drawings. However, this task faces the challenges of complicated design shapes as well as cumbersome and cluttered annotations on drawings, which interfere with the vector extraction heavily. In this article, the transmission tower containing the most complex structure is taken as the research object, and a semantic segmentation network is constructed to first segment the shape masks from the pixel-level drawings. Preprocessing and postprocessing are also proposed to ensure the stability and accuracy of the shape mask segmentation. Then, based on the obtained shape masks, a vector extraction network guided by heatmaps is designed to extract structural vectors by fusing the features from node heatmap and skeleton heatmap, respectively. Compared with the state-of-the-art methods, experiment results illustrate that the proposed semantic segmentation method can effectively eliminate the interference of many elements on drawings to segment the shape masks effectively, meanwhile, the model trained by the proposed vector extraction network can accurately extract the vectors such as nodes and line connections, avoiding redundant vector detection. The proposed method lays a solid foundation for automatic 3D model reconstruction and contributes to technological advancements in relevant fields. 展开更多
关键词 design drawings semantic segmentation deep learning vector extraction dIGITIZATION 3d modeling
在线阅读 下载PDF
Reorientation of hydraulic fractures and stress-shadow effect in double-well fracturing of hydrocarbon reservoirs:3D numerical model and analysis
11
作者 Yang Ju Yang Li +1 位作者 Yongming Yang Yongliang Wang 《International Journal of Mining Science and Technology》 2025年第4期499-517,共19页
Multistage fracturing technology has been used to enhance tight hydrocarbon resource recovery.Determining the proper well spacing and fracturing strategy is crucial for generating a complex fracture network that facil... Multistage fracturing technology has been used to enhance tight hydrocarbon resource recovery.Determining the proper well spacing and fracturing strategy is crucial for generating a complex fracture network that facilitates oil and gas flow in reservoirs.The stress-shadow effect that occurs between multiple wells significantly affects the development of fracture networks in reservoirs.However,the quantification of the stress-shadow effect and its influence on fracture networks has not been satisfactorily resolved because of the difficulties in detecting and identifying fracture propagation and reorientation in reservoirs.In this study,based on the geological information from the Shengli oilfield,we applied a hybrid finite element-discrete element method to analyze engineering-scale three-dimensional fracture propagation and reorientation by altering well spacings and fracturing strategies.The results indicate that the fracturing area generated by the synchronous fracturing scheme is much smaller than those generated by the sequential and alternative schemes.An alternative hydrofracturing scheme is optimal with respect to fracturing area.The stress-blind area was defined to quantify the mechanical disturbance between adjacent wells.Our study improves the understanding of the effect of fracturing schemes on fracture networks and the impact of independent factors contributing to stress-shadow effects. 展开更多
关键词 Multistage fracturing double wells Stress-shadow effect Fracturing strategies 3d reorientation Engineering-scale model
在线阅读 下载PDF
Detailed in-depth mapping of the world largest anorthositic complex:Magnetic anomalies,2.5-3D modelling and emplacement constraints of the Kunene Complex(KC),SW Angola
12
作者 T.Mochales E.Merino-Martínez +11 位作者 C.Rey-Moral A.Machadinho J.Carvalho P.Represas J.L.García-Lobón M.C.Feria R.Martín-Banda M.T.López-Bahut D.Alves E.Ramalho J.Manuel D.Cordeiro 《Geoscience Frontiers》 2025年第3期261-285,共25页
The Kunene Complex(KC)represents a very large Mesoproterozoic igneous body,mainly composed of anorthosites and gabbroic rocks that extends from SW Angola to NW Namibia(outcropping 18,000 km^(2),NE-SW trend,and ca.350 ... The Kunene Complex(KC)represents a very large Mesoproterozoic igneous body,mainly composed of anorthosites and gabbroic rocks that extends from SW Angola to NW Namibia(outcropping 18,000 km^(2),NE-SW trend,and ca.350 km long and up to 50 km wide).Little is known about its structure at depth.Here,we use recently acquired aerogeophysical data to accurately determine its hidden extent and to unravel its morphology at depth.These data have been interpreted and modelled to investigate the unexposed KC boundaries,reconstructing the upper crustal structure(between 0 and 15 km depth)overlain by the thin sedimentary cover of the Kalahari Basin.The modelling reveals that the KC was emplaced in the upper crust and extends in depth up to ca.5 km,showing a lobular geometry and following a large NE-SW to NNE-SSW linear trend,presumably inherited from older Paleoproterozoic structures.The lateral continuation of the KC to the east(between 50 and 125 km)beneath the Kalahari Cenozoic sediments suggests an overall size three times the outcropping dimension(about 53,500 km^(2)).This affirmation clearly reinforces the economic potential of this massif,related to the prospecting of raw materials and certain types of economic mineralization(Fe-Ti oxides,metallic sulphides or platinum group minerals).Up to 11 lobes have been isolated with dimensions ranging from 135.5 to 37.3 km in length and 81.9 to 20.7 km in width according to remanent bodies revealed by TMI mapping.A total volume of 65,184 km3 was calculated only for the magnetically remanent bodies of the KC.A long-lasting complex contractional regime,where large strike-slip fault systems were involved,occurred in three kinematic pulses potentially related to a change of velocity or convergence angle acting on previous Paleoproterozoic inherited sutures.The coalescent magmatic pulses can be recognized by means of magnetic anomalies,age of the bodies as well as the lineations inferred in this work:(i)Emplacement of the eastern mafic bodies and granites in a stage of significant lateral extension in a transtensional context between 1500 Ma and 1420 Ma;(ii)Migration of the mantle derived magmas westwards with deformation in a complex contractional setting with shearing structures involving western KC bodies and basement from 1415 Ma to 1340 Ma;(iii)NNW-SSE extensional structures are relocated westwards,involving mantle magmas,negative flower structures and depression that led to the formation of late Mesoproterozoic basins from 1325 Ma to 1170 Ma.Additionally,we detect several first and second order structures to place the structuring of the KC in a craton-scale context in relation to the crustal structures detected in NW Namibia. 展开更多
关键词 ANGOLA Kunene Complex(KC) Magnetic prospecting 2.5 modelling 3d inversion
在线阅读 下载PDF
Evaluation of scale effects in physical modeling of combined ogee and sharp-crested weir flow using a 3D CFD model
13
作者 James Zulfan Bobby Minola Ginting Ravi Anthony Tartandyo 《Water Science and Engineering》 2025年第2期225-235,共11页
Research on scale effects on flows over weirs has been conducted on a limited basis, primarily focusing on flows upstream of a single-type weir, such as ogee, broad-crested, and sharp-crested (linear and non-linear) w... Research on scale effects on flows over weirs has been conducted on a limited basis, primarily focusing on flows upstream of a single-type weir, such as ogee, broad-crested, and sharp-crested (linear and non-linear) weirs. However, the scale effects downstream of these single-type weirs have not been thoroughly investigated. This study examined the scale effects on flows over a combined weir system consisting of an ogee weir and a sharp-crested weir, both upstream and downstream, utilizing physical modeling at a 1:33.33 scale based on Froude similarity and three-dimensional (3D) computational fluid dynamics (CFD) modeling. The sharp-crested weir in this study was represented by two sluice gates that remain closed and submerged during flood events. The experimental data confirmed that the equivalent discharge coefficients of the combined weir system behaved similarly to those of a sharp-crested weir across various H/P (where H is the total head, and P is the weir height) values. However, scale effects on the discharge rating curve due to surface tension and viscosity could only be minimized when H/P > 0.4, Re > 26 959, and We > 240 (where Re and We are the Reynolds and Weber numbers, respectively), provided that the water depth exceeded 0.042 m above the crest. Additionally, Re greater than 4 × 104 was necessary to minimize scale effects caused by viscosity in flows in the spillway channel and stilling basin (with baffle blocks). The limiting criteria aligned closely with existing literature. This study offers valuable insights for practical applications in hydraulic engineering in the future. 展开更多
关键词 3d CFd Ogee weir Physical modeling Sharp-crested weir Sluice gate Scale effects
在线阅读 下载PDF
Cancer 3D Models:Essential Tools for Understanding and Overcoming Drug Resistance
14
作者 Sofija Jovanovic Stojanov Marija Grozdanic +3 位作者 Mila Ljujic Sandra Dragicevic Miodrag Dragoj Jelena Dinic 《Oncology Research》 2025年第10期2741-2785,共45页
Anticancer drug resistance remains a major challenge in cancer treatment hindering the efficacy of chemotherapy and targeted therapies.Conventional two-dimensional(2D)cell cultures cannot replicate the complexity of t... Anticancer drug resistance remains a major challenge in cancer treatment hindering the efficacy of chemotherapy and targeted therapies.Conventional two-dimensional(2D)cell cultures cannot replicate the complexity of the in vivo tumor microenvironment(TME),limiting their utility for drug resistance research.Therefore,three-dimensional(3D)tumor models have proven to be a promising alternative for investigating chemoresistance mechanisms.In this review,various cancer 3D models,including spheroids,organoids,scaffold-based models,and bioprinted models,are comprehensively evaluated with a focus on their application in drug resistance studies.We discuss the materials,properties,and advantages of each model,highlighting their ability to better mimic the TME and represent complex mechanisms of drug resistance such as epithelial-mesenchymal transition(EMT),drug efflux,and tumor-stroma interactions.Furthermore,we investigate the limitations of these models,including scalability,reproducibility and technical challenges,as well as their potential therapeutic impact on personalized medicine.Through a thorough comparison of model performance,we provide insights into the strengths and weaknesses of each approach and offer guidance for model selection based on specific research needs. 展开更多
关键词 Cancer three-dimensional(3d)models cancer drug resistance preclinical cancer models
暂未订购
Enhancing 3D U-Net with Residual and Squeeze-and-Excitation Attention Mechanisms for Improved Brain Tumor Segmentation in Multimodal MRI
15
作者 Yao-Tien Chen Nisar Ahmad Khursheed Aurangzeb 《Computer Modeling in Engineering & Sciences》 2025年第7期1197-1224,共28页
Accurate and efficient brain tumor segmentation is essential for early diagnosis,treatment planning,and clinical decision-making.However,the complex structure of brain anatomy and the heterogeneous nature of tumors pr... Accurate and efficient brain tumor segmentation is essential for early diagnosis,treatment planning,and clinical decision-making.However,the complex structure of brain anatomy and the heterogeneous nature of tumors present significant challenges for precise anomaly detection.While U-Net-based architectures have demonstrated strong performance in medical image segmentation,there remains room for improvement in feature extraction and localization accuracy.In this study,we propose a novel hybrid model designed to enhance 3D brain tumor segmentation.The architecture incorporates a 3D ResNet encoder known for mitigating the vanishing gradient problem and a 3D U-Net decoder.Additionally,to enhance the model’s generalization ability,Squeeze and Excitation attention mechanism is integrated.We introduce Gabor filter banks into the encoder to further strengthen the model’s ability to extract robust and transformation-invariant features from the complex and irregular shapes typical in medical imaging.This approach,which is not well explored in current U-Net-based segmentation frameworks,provides a unique advantage by enhancing texture-aware feature representation.Specifically,Gabor filters help extract distinctive low-level texture features,reducing the effects of texture interference and facilitating faster convergence during the early stages of training.Our model achieved Dice scores of 0.881,0.846,and 0.819 for Whole Tumor(WT),Tumor Core(TC),and Enhancing Tumor(ET),respectively,on the BraTS 2020 dataset.Cross-validation on the BraTS 2021 dataset further confirmed the model’s robustness,yielding Dice score values of 0.887 for WT,0.856 for TC,and 0.824 for ET.The proposed model outperforms several state-of-the-art existing models,particularly in accurately identifying small and complex tumor regions.Extensive evaluations suggest integrating advanced preprocessing with an attention-augmented hybrid architecture offers significant potential for reliable and clinically valuable brain tumor segmentation. 展开更多
关键词 3d MRI artificial intelligence deep learning AI in healthcare attention mechanism u-net medical image analysis brain tumor segmentation BraTS 2021 BraTS 2020
暂未订购
Mechanical behavior of SiC reinforced ZA63 Mg matrix composites: Experiments and 3D finite element modelling
16
作者 Chong Wang Zelong Du +6 位作者 Enyu Guo Shuying Bai Zongning Chen Huijun Kang Guohao Du Yanling Xue Tongmin Wang 《Journal of Magnesium and Alloys》 2025年第3期1294-1309,共16页
In this work,the microstructure evolution and mechanical behavior of extruded SiC/ZA63 Mg matrix composites are investigated via combined experimental study and three-dimensionalfinite element modelling(3D FEM)based on... In this work,the microstructure evolution and mechanical behavior of extruded SiC/ZA63 Mg matrix composites are investigated via combined experimental study and three-dimensionalfinite element modelling(3D FEM)based on the actual 3D microstructure achieved by synchrotron tomography.The results show that the average grain size of composite increases from 0.57μm of 8μm-SiC/ZA63 to 8.73μm of 50μm-SiC/ZA63.The type of texture transforms from the typicalfiber texture in 8μm-SiC/ZA63 to intense basal texture in 50μm-SiC/ZA63 composite and the intensity of texture increases sharply with increase of SiC particle size.The dynamic recrystallization(DRX)mechanism is also changed with increasing SiC particle size.Experimental and simulation results verify that the strength and elongation both decrease with increase of SiC particle size.The 8μm-SiC/ZA63 composite possesses the optimal mechanical property with yield strength(YS)of 383 MPa,ultimate tensile strength(UTS)of 424 MPa and elongation of 6.3%.The outstanding mechanical property is attributed to the ultrafine grain size,high-density precipitates and dislocation,good loading transfer effect and the interface bonding between SiC and matrix,as well as the weakened basal texture.The simulation results reveal that the micro-cracks tend to initiate at the interface between SiC and matrix,and then propagate along the interface between particle and Mg matrix or at the high strain and stress regions,and further connect with other micro-cracks.The main fracture mechanism in 8μm-SiC/ZA63 composite is ductile damage of matrix and interfacial debonding.With the increase of particle size,interface strength and particle strength decrease,and interface debonding and particle rupture become the main fracture mechanism in the 30μm-and 50μm-SiC/ZA63 composites. 展开更多
关键词 Mg matrix composite Synchrotron tomography 3d finite element model Microstructure evolution Mechanical property
在线阅读 下载PDF
A novel heuristic pathfinding algorithm for 3D security modeling and vulnerability assessment
17
作者 Jun Yang Yue-Ming Hong +2 位作者 Yu-Ming Lv Hao-Ming Ma Wen-Lin Wang 《Nuclear Science and Techniques》 2025年第5期152-166,共15页
Vulnerability assessment is a systematic process to identify security gaps in the design and evaluation of physical protection systems.Adversarial path planning is a widely used method for identifying potential vulner... Vulnerability assessment is a systematic process to identify security gaps in the design and evaluation of physical protection systems.Adversarial path planning is a widely used method for identifying potential vulnerabilities and threats to the security and resilience of critical infrastructures.However,achieving efficient path optimization in complex large-scale three-dimensional(3D)scenes remains a significant challenge for vulnerability assessment.This paper introduces a novel A^(*)-algorithmic framework for 3D security modeling and vulnerability assessment.Within this framework,the 3D facility models were first developed in 3ds Max and then incorporated into Unity for A^(*)heuristic pathfinding.The A^(*)-heuristic pathfinding algorithm was implemented with a geometric probability model to refine the detection and distance fields and achieve a rational approximation of the cost to reach the goal.An admissible heuristic is ensured by incorporating the minimum probability of detection(P_(D)^(min))and diagonal distance to estimate the heuristic function.The 3D A^(*)heuristic search was demonstrated using a hypothetical laboratory facility,where a comparison was also carried out between the A^(*)and Dijkstra algorithms for optimal path identification.Comparative results indicate that the proposed A^(*)-heuristic algorithm effectively identifies the most vulnerable adversarial pathfinding with high efficiency.Finally,the paper discusses hidden phenomena and open issues in efficient 3D pathfinding for security applications. 展开更多
关键词 Physical protection system 3d modeling and simulation Vulnerability assessment A^(*)Heuristic Pathfinding dijkstra algorithm
在线阅读 下载PDF
Automatic identification of discontinuities and refined modeling of rock blocks from 3D point cloud data of rock surfaces
18
作者 Yaopeng Ji Shengyuan Song +5 位作者 Jianping Chen Jingyu Xue Jianhua Yan Yansong Zhang Di Sun Qing Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 2025年第5期3093-3106,共14页
The spatial distribution of discontinuities and the size of rock blocks are the key indicators for rock mass quality evaluation and rockfall risk assessment.Traditional manual measurement is often dangerous or unreach... The spatial distribution of discontinuities and the size of rock blocks are the key indicators for rock mass quality evaluation and rockfall risk assessment.Traditional manual measurement is often dangerous or unreachable at some high-steep rock slopes.In contrast,unmanned aerial vehicle(UAV)photogrammetry is not limited by terrain conditions,and can efficiently collect high-precision three-dimensional(3D)point clouds of rock masses through all-round and multiangle photography for rock mass characterization.In this paper,a new method based on a 3D point cloud is proposed for discontinuity identification and refined rock block modeling.The method is based on four steps:(1)Establish a point cloud spatial topology,and calculate the point cloud normal vector and average point spacing based on several machine learning algorithms;(2)Extract discontinuities using the density-based spatial clustering of applications with noise(DBSCAN)algorithm and fit the discontinuity plane by combining principal component analysis(PCA)with the natural breaks(NB)method;(3)Propose a method of inserting points in the line segment to generate an embedded discontinuity point cloud;and(4)Adopt a Poisson reconstruction method for refined rock block modeling.The proposed method was applied to an outcrop of an ultrahigh steep rock slope and compared with the results of previous studies and manual surveys.The results show that the method can eliminate the influence of discontinuity undulations on the orientation measurement and describe the local concave-convex characteristics on the modeling of rock blocks.The calculation results are accurate and reliable,which can meet the practical requirements of engineering. 展开更多
关键词 Three-dimensional(3d)point cloud Rock mass Automatic identification Refined modeling Unmanned aerial vehicle(UAV)
在线阅读 下载PDF
Integrating geographic information system and 3D virtual reality for optimized modeling of large-scale photovoltaic wind hybrid system:A case study in Dakhla City,Morocco
19
作者 Elmostafa Achbab Rachid Lambarki +1 位作者 Hassan Rhinane Dennoun Saifaoui 《Energy Geoscience》 2025年第2期174-193,共20页
This research pioneers the integration of geographic information systems(GIS)and 3D modeling within a virtual reality(VR)framework to assess the viability and planning of a 20 MW hybrid wind-solarphotovoltaic(PV)syste... This research pioneers the integration of geographic information systems(GIS)and 3D modeling within a virtual reality(VR)framework to assess the viability and planning of a 20 MW hybrid wind-solarphotovoltaic(PV)system connected to the local grid.The study focuses on Dakhla,Morocco,a region with vast untapped renewable energy potential.By leveraging GIS,we are innovatively analyzing geographical and environmental factors that influence optimal site selection and system design.The incorporation of VR technologies offers an unprecedented level of realism and immersion,allowing stakeholders to virtually experience the project's impact and design in a dynamic,interactive environment.This novel methodology includes extensive data collection,advanced modeling,and simulations,ensuring that the hybrid system is precisely tailored to the unique climatic and environmental conditions of Dakhla.Our analysis reveals that the region possesses a photovoltaic solar potential of approximately2400 k Wh/m^(2) per year,with an average annual wind power density of about 434 W/m^(2) at an 80-meter hub height.Productivity simulations indicate that the 20 MW hybrid system could generate approximately 60 GWh of energy per year and 1369 GWh over its 25-year lifespan.To validate these findings,we employed the System Advisor Model(SAM)software and the Global Solar Photovoltaic Atlas platform.This comprehensive and interdisciplinary approach not only provides a robust assessment of the system's feasibility but also offers valuable insights into its potential socio-economic and environmental impact. 展开更多
关键词 Geographic information systems 3d virtual reality(VR)modeling Wind energy Solar photovoltaic(PV)energy Hybrid renewable energy system assessment
在线阅读 下载PDF
3D模型及混合现实全息影像技术在住培女性压力性尿失禁手术教学的应用研究 被引量:1
20
作者 郭景阳 崔振宇 +3 位作者 王文涛 李松 宋士超 古德强 《中国毕业后医学教育》 2025年第3期184-188,共5页
目的探讨3 D模型及混合现实全息影像系统在住院医师规范化培训(简称住培)女性压力性尿失禁(stress urinary incontinence,SUI)手术教学中的应用效果。方法利用随机数字表将2021年7月13日到2023年3月30日60名于泌尿外科接受住培的住院医... 目的探讨3 D模型及混合现实全息影像系统在住院医师规范化培训(简称住培)女性压力性尿失禁(stress urinary incontinence,SUI)手术教学中的应用效果。方法利用随机数字表将2021年7月13日到2023年3月30日60名于泌尿外科接受住培的住院医师随机分为观察组和对照组,每组各30例。选取60例女性SUI患者,术前行骨盆CT成像,利用软件生成3 D虚拟模型,打印3 D骨盆模型。观察组利用3 D模型进行骨盆结构的教学,熟悉骨盆解剖,并将其应用于手术前计划、术中解剖定位以及手术入路观察。住院医师佩戴Hololens眼镜,可实现虚拟对象与真实世界交互。对照组按常规方法进行教学,即指导医师讲解幻灯片、解剖图片、手术中操作注意事项等。对比分析两组住院医师的理论水平掌握情况、手术操作熟练程度以及对教学方法的满意度。结果观察组盆底解剖、SUI手术步骤以及注意事项等项目平均成绩、对教学方式的满意度、穿刺成功率均高于对照组,差异有统计学意义(P<0.05),观察组每个项目的答题时长均短于对照组(P<0.01)。结论3 D模型及混合现实全息影像系统可增强住院医师对复杂的盆底解剖结构的认识,有利于提高女性SUI手术的教学效果。 展开更多
关键词 3 d模型 混合现实全息影像 住院医师规范化培训 压力性尿失禁 手术教学
在线阅读 下载PDF
上一页 1 2 127 下一页 到第
使用帮助 返回顶部