The characteristics of nonmetallic inclusions formed during steel production have a significant influence on steel performance.In this paper,studies on inclusions using confocal scanning laser microscopy(CSLM)are revi...The characteristics of nonmetallic inclusions formed during steel production have a significant influence on steel performance.In this paper,studies on inclusions using confocal scanning laser microscopy(CSLM)are reviewed and summarized,particularly the col-lision of various inclusions,dissolution of inclusions in liquid slag,and reactions between inclusions and steel.Solid inclusions exhibited a high collision tendency,whereas pure liquid inclusions exhibited minimal collisions because of the small attraction force induced by their<90°contact angle with molten steel.The collision of complex inclusions in molten steel was not included in the scope of this study and should be evaluated in future studies.Higher CaO/Al_(2)O_(3)and CaO/SiO_(2)ratios in liquid slag promoted the dissolution of Al_(2)O_(3)-based in-clusions.The formation of solid phases in the slag should be prevented to improve dissolution of inclusions.To accurately simulate the dissolution of inclusions in liquid slag,in-situ observation of the dissolution of inclusions at the steel-slag interface is necessary.Using a combination of CSLM and scanning electron microscopy-energy dispersive spectroscopy,the composition and morphological evolution of the inclusions during their modification by the dissolved elements in steel were observed and analyzed.Although the in-situ observa-tion of MnS and TiN precipitations has been widely studied,the in-situ observation of the evolution of oxide inclusions in steel during so-lidification and heating processes has rarely been reported.The effects of temperature,heating and cooling rates,and inclusion character-istics on the formation of acicular ferrites(AFs)have been widely studied.At a cooling rate of 3-5 K/s,the order of AF growth rate in-duced by different inclusions,as reported in literature,is Ti-O<Ti-Ca-Zr-Al-O<Mg-O<Ti-Zr-Al-O<Mn-Ti-Al-O<Ti-Al-O<Zr-Ti-Al-O.Further comprehensive experiments are required to investigate the quantitative relationship between the formation of AFs and inclusions.展开更多
The high-temperature dissolution behavior of primary carbides in samples taken from GCr15 continuous-casting bloom was observed in-situ by confocal laser scanning microscopy.Equations were fitted to the dissolution ki...The high-temperature dissolution behavior of primary carbides in samples taken from GCr15 continuous-casting bloom was observed in-situ by confocal laser scanning microscopy.Equations were fitted to the dissolution kinetics of primary carbides during either heating or soaking.Dissolution of carbides proceeded in three stages(fast→slow→faster)as either temperature or holding time was increased.During the heating process and during the first and third stages of the soaking process,the original size of the carbides determined the steepness of the slope,but during the middle(“slow”)stage of the soaking process,the slope remained zero.The initial size of the carbides varied greatly,but their final dissolution temperature fell within the narrow range of 1210-1235℃,and the holding time remained within 50 min.Fractal analysis was used to study the morphological characteristics of small and medium-sized carbides during the dissolution process.According to changes in the fractal dimension before and after soaking,the carbides tended to evolve towards a more regular morphology.展开更多
Clayey-silt natural gas hydrate reservoirs in the South China Sea exhibit loose and unconsolidated structures, heterogeneous pore structures, high clay mineral contents, and strong hydrophilicity. These characteristic...Clayey-silt natural gas hydrate reservoirs in the South China Sea exhibit loose and unconsolidated structures, heterogeneous pore structures, high clay mineral contents, and strong hydrophilicity. These characteristics complicate the gas-water two-phase flow process in porous media following hydrate decomposition, posing challenges for efficient development. This study examines the transport response of clayey-silt reservoir samples from the Shenhu area using gas-water two-phase flow experiments and CT scanning to explore changes in pore structure, gas-water distribution, and relative permeability under varying flow conditions. The results indicate that pore heterogeneity significantly influences flow characteristics. Gas preferentially displaces water in larger pores, forming fracture-like pores, which serve as preferential flow channels for gas migration. The preferential flow channels enhance gas-phase permeability up to 19 times that of the water phase when fluid pressures exceed total stresses. However,small pores retain liquid, leading to a high residual water saturation of 0.561. CT imaging reveals that these hydro-fractures improve gas permeability but also confine gas flow to specific channels. Pore network analysis shows that gas injection expands the pore-throat network, enhancing connectivity and forming fracture-like pores. Residual water remains trapped in smaller pores and throats, while structural changes, including new fractures, improve gas flow pathways and overall connectivity. Relative permeability curves demonstrate a narrow gas-water cocurrent-flow zone, a right-shifted iso-permeability point and high reservoir capillary pressure, indicating a strong "water-blocking" effect. The findings suggest that optimizing reservoir stimulation techniques to enhance fracture formation, reduce residual water saturation, and improve gas flow capacity is critical for efficient hydrate reservoir development.展开更多
The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods fo...The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods for centroid measurement often necessitate custom equipment and specialized positioning devices,leading to high costs and limited accuracy.Here,we present a centroid measurement method that integrates 3D scanning technology,enabling accurate measurement of centroid across various types of objects without the need for specialized positioning fixtures.A theoretical framework for centroid measurement was established,which combined the principle of the multi-point weighing method with 3D scanning technology.The measurement accuracy was evaluated using a designed standard component.Experimental results demonstrate that the discrepancies between the theoretical and the measured centroid of a standard component with various materials and complex shapes in the X,Y,and Z directions are 0.003 mm,0.009 mm,and 0.105 mm,respectively,yielding a spatial deviation of 0.106 mm.Qualitative verification was conducted through experimental validation of three distinct types.They confirmed the reliability of the proposed method,which allowed for accurate centroid measurements of various products without requiring positioning fixtures.This advancement significantly broadened the applicability and scope of centroid measurement devices,offering new theoretical insights and methodologies for the measurement of complex parts and systems.展开更多
Cleat serves as the primary flow pathway for coalbed methane(CBM)and water.However,few studies consider the impact of local contact on two-phase flow within cleats.A visual generalized model of endogenous cleats was c...Cleat serves as the primary flow pathway for coalbed methane(CBM)and water.However,few studies consider the impact of local contact on two-phase flow within cleats.A visual generalized model of endogenous cleats was constructed based on microfluidics.A microscopic and mesoscopic observation technique was proposed to simultaneously capture gas-liquid interface morphology of pores and throat and the two-phase flow characteristics in entire cleat system.The local contact characteristics of cleats reduced absolute permeability,which resulted in a sharp increase in the starting pressure.The reduced gas flow capacity narrowed the co-infiltration area and decreased water saturation at the isotonic point in a hydrophilic environment.The increased local contact area of cleats weakened gas phase flow capacity and narrowed the co-infiltration area.Jumping events occurred in methane-water flow due to altered porosity caused by local contact in cleats.The distribution of residual phases changed the jumping direction on the micro-scale as well as the dominant channel on the mesoscale.Besides,jumping events caused additional energy dissipation,which was ignored in traditional two-phase flow models.This might contribute to the overestimation of relative permeability.The work provides new methods and insights for investigating unsaturated flow in complex porous media.展开更多
In this study, the three-dimensional non-premixed two-phase kerosene/air rotating detonation engines with different isolator configurations and throat area ratios are simulated by the Eulerian-Lagrangian method. The e...In this study, the three-dimensional non-premixed two-phase kerosene/air rotating detonation engines with different isolator configurations and throat area ratios are simulated by the Eulerian-Lagrangian method. The effects of the divergence, straight, and convergence isolators on the rotating detonation wave dynamics and the upstream oblique shock wave propagation mechanism are analyzed. The differences in the rotating detonation wave behaviors between ground and flight operations are clarified.The results indicate that the propagation regimes of the upstream oblique shock wave depend on the isolator configurations and operation conditions. With a divergence isolator, the airflow is accelerated throughout the isolator and divergence section, leading to a maximum Mach number(~1.8) before the normal shock. The total pressure loss reaches the largest, and the detonation pressure drops. The upstream oblique shock wave can be suppressed within the divergence section with the divergence isolator.However, for the straight and convergence isolators, the airflow in the isolator with a larger ψ_(1)(0.3 and0.4) can suffer from the disturbance of the upstream oblique shock wave. The critical incident angle is around 39° at ground operation conditions. The upstream oblique shock wave tends to be suppressed when the engine operates under flight operation conditions. The critical pressure ratio β_(cr0) is found to be able to help in distinguishing the propagation regimes of the upstream oblique shock wave. Slightly below or above the β_(cr0) can obtain different marginal propagation results. The high-speed airflow in the divergence section affects the fuel droplet penetration distance, which deteriorates the reactant mixing and the detonation area. Significant detonation velocity deficits are observed and the maximum velocity deficit reaches 26%. The results indicate the engine channel design should adopt different isolator configurations based on the purpose of total pressure loss or disturbance suppression. This study can provide useful guidance for the channel design of a more complete two-phase rotating detonation engine.展开更多
Two-phase partitioning bioreactors(TPPBs)have been widely used because they overcome the mass-transfer limitation of hydrophobic volatile organic compounds(VOCs)in waste gas biological treatments.Understanding the mec...Two-phase partitioning bioreactors(TPPBs)have been widely used because they overcome the mass-transfer limitation of hydrophobic volatile organic compounds(VOCs)in waste gas biological treatments.Understanding the mechanisms of mass-transfer enhancement in TPPBs would enable efficient predictions for further industrial applications.In this study,influences of gradually increasing silicone oil ratio on the TPPB was explored,and a 94.35%reduction of the n-hexane partition coefficient was observed with 0.1 vol.%silicone,which increased to 80.7%along with a 40-fold removal efficiency enhancement in the stabilised removal period.The elimination capacity increased from 1.47 to 148.35 g/(m^(3)·h),i.e.a 101-fold increase compared with that of the single-phase reactors,when 10 vol.%(3 Critical Micelle Concentration)silicone oil was added.The significantly promoted partition coefficient was the main reason for the mass transfer enhancement,which covered the negative influences of the decreased total mass-transfer coefficient with increasing silicone oil volume ratio.The gradually rising stirring rate was benefit to the n-hexane removal,which became negative when the dominant resistance shifted from mass transfer to biodegradation.Moreover,a mass-transfer-reaction kinetic model of the TPPB was constructed based on the balance of n-hexane concentration,dissolved oxygen and biomass.Similar to the mechanism,the partition factor was predicted sensitive to the removal performance,and another five sensitive parameters were found simultaneously.This forecasting method enables the optimisation of TPPB performance and provides theoretical support for hydrophobic VOCs degradation.展开更多
To investigate the nucleation behavior during the single-phased metallic solidification process,the commercial ultrapure ferritic stainless steels with no(Initial steel)and various melt treatments(R1,MR1,Y2,MY1,and M1...To investigate the nucleation behavior during the single-phased metallic solidification process,the commercial ultrapure ferritic stainless steels with no(Initial steel)and various melt treatments(R1,MR1,Y2,MY1,and M1 steels)were used to carry out the differential scanning colorimetry(DSC)and high-temperature confocal laser scanning microscope(HT-CLSM)experiments.Based on the results of DSC experiments,the equilibrium solidification process as well as the relationship among the critical undercooling degree(△T_(c)^(DSC)),latent heat of fusion/crystallization(△H_(f)/△H_(c)),equiaxed grain ratio(ER),and average grain size(△_(ave)^(ingot))was revealed.ER is increased with the decreasing△T_(c)^(DSC)and increasing△H_(f)/△H_(c);however,△_(ave)^(ingot)is decreased with them.Referring to the results of HT-CLSM experiments,the average sizes of micro-/macrostructures(d_(ave)/D_(ave)/)are decreased with the increasing cooling rate,as well as the difference between and apparent critical undercooling degree(△T_(c)^(CLSM))was revealed.The heterogeneous nucleation of the crystal nuclei occurs only if△T_(c)^(CLSM)>△T_(c)^(DSC).Combining with the interfacial wetting-lattice mismatch heterogeneous nucleation model,the dynamic mechanism of the metallic solidification was revealed.The as-cast grains of the melt-treated samples were obviously refined,owing to the much higher actual heterogeneous nucleation rates(I_(heter.,i))obtained through melt treatments,and the heterogeneous nucleation rates(I_(heter.,ij))for all samples are increased with the cooling rates,firmly confirming that the as-cast grains of each sample could be refined by the increasing cooling rates.展开更多
With the increasing miniaturization of systems and surging demand for power density,accurate prediction and control of two-phase flow pressure drop have become a core challenge restricting the performance of microchan...With the increasing miniaturization of systems and surging demand for power density,accurate prediction and control of two-phase flow pressure drop have become a core challenge restricting the performance of microchannel heat exchangers.Pressure drop,a critical hydraulic characteristic,serves as both a natural constraint for cooling systems and determines the power required to pump the working fluid through microchannels.This paper reviews the characteristics,prediction models,and optimization measures of two-phase flow pressure drop for low-boiling-point working fluids in microchannels.It systematically analyzes key influencing factors such as fluid physical properties,operating conditions,channel geometry,and flow patterns,and discusses the complex mechanisms of pressure drop under the coupling effect of multi-physical fields.Mainstream prediction models are reviewed:the homogeneous flow model simplifies calculations but shows large deviations at low quality;the separated flow model considers interphase interactions and can be applied to micro-scales after modification;the flow-pattern-based model performs zoned modeling but relies on subjective classification;machine learning improves prediction accuracy but faces the“black-box”problem.In terms of optimization,channel designs are improved through porous structures and micro-rib arrays,and flow rate distribution is optimized using splitters to balance pressure drop and heat transfer performance.This study provides theoretical support for microchannel thermal management in high-power-density devices.展开更多
By combining with an improved model on engraving process,a two-phase flow interior ballistic model has been proposed to accurately predict the flow and energy conversion behaviors of pyrotechnic actuators.Using comput...By combining with an improved model on engraving process,a two-phase flow interior ballistic model has been proposed to accurately predict the flow and energy conversion behaviors of pyrotechnic actuators.Using computational fluid dynamics(CFD),the two-phase flow and piston engraving characteristics of a pyrotechnic actuator are investigated.Initially,the current model was utilized to examine the intricate,multi-dimensional flow,and energy conversion characteristics of the propellant grains and combustion gas within the pyrotechnic actuator chamber.It was discovered that the combustion gas on the wall's constant transition from potential to kinetic energy,along with the combined effect of the propellant motion,are what create the pressure oscillation within the chamber.Additionally,a numerical analysis was conducted to determine the impact of various parameters on the pressure oscillation and piston motion,including pyrotechnic charge,pyrotechnic particle size,and chamber structural dimension.The findings show that decreasing the pyrotechnic charge will lower the terminal velocity,while increasing and decreasing the pyrotechnic particle size will reduce the pressure oscillation in the chamber.The pyrotechnic particle size has minimal bearing on the terminal velocity.The results of this investigation offer a trustworthy forecasting instrument for comprehending and creating pyrotechnic actuator designs.展开更多
The exosomes hold significant potential in disease diagnosis and therapeutic interventions.The objective of this study was to investigate the potential of aqueous two-phase systems(ATPSs)for the separation of bovine m...The exosomes hold significant potential in disease diagnosis and therapeutic interventions.The objective of this study was to investigate the potential of aqueous two-phase systems(ATPSs)for the separation of bovine milk exosomes.The milk exosome partition behaviors and bovine milk separation were investigated,and the ATPSs and bovine milk whey addition was optimized.The optimal separation conditions were identified as 16%(mass)polyethylene glycol 4000,10%(mass)dipotassium phosphate,and 1%(mass)enzymatic hydrolysis bovine milk whey.During the separation process,bovine milk exosomes were predominantly enriched in the interphase,while protein impurities were primarily found in the bottom phase.The process yielded bovine milk exosomes of 2.0×10^(11)particles per ml whey with high purity(staining rate>90%,7.01×10^(10)particles per mg protein)and high uniformity(polydispersity index<0.03).The isolated exosomes were characterized and identified by transmission electron microscopy,zeta potential and size distribution.The results demonstrated aqueous two-phase extraction possesses a robust capability for the enrichment and separation of exosomes directly from bovine milk whey,presenting a novel approach for the large-scale isolation of exosomes.展开更多
As space technology advances,thermal control systems must effectively collect and dissipate heat from distributed,multi-source environments.Loop heat pipe is a highly reliable two-phase heat transfer component,but it ...As space technology advances,thermal control systems must effectively collect and dissipate heat from distributed,multi-source environments.Loop heat pipe is a highly reliable two-phase heat transfer component,but it has several limitations when addressing multi-source heat dissipation.Inspired by the transport and heat dissipation system of plants,large trees achieve stable and efficient liquid supply under the influence of two driving forces:capillary force during transpiration in the leaves(pull)and root pressure generated by osmotic pressure in the roots(push).The root pressure provides an effective liquid supply with a driving force exceeding 2 MPa,far greater than the driving force in conventional capillary-pumped two-phase loops.Research has shown that osmotic heat pipes offer a powerful driving force,and combining osmotic pressure with capillary force has significant advantages.Therefore,this paper designs a multi-evaporator,dual-drive two-phase loop,using both osmotic pressure and capillary force to solve the multi-source heat dissipation challenge.First,a transmembrane water flux model for the osmotic pressure-driven device was established to predict the maximum heat transfer capacity of the dual-drive two-phase loop.Then,an experimental setup for a multi-evaporator“osmotic pressure+capillary force”dual-drive two-phase loop was constructed,capable of transferring at least 235 W of power under a reverse gravity condition of 20 m.The study also analyzed the effects of reverse gravity height,heat load distribution among the three evaporators,startup sequence,and varying branch resistances on the performance of the dual-drive two-phase loop.展开更多
Shale gas production involves complex gas-water two-phase flow,with flow patterns in proppant-filled fractures playing a critical role in determining production efficiency.In this study,3D geometric models of 40/70 me...Shale gas production involves complex gas-water two-phase flow,with flow patterns in proppant-filled fractures playing a critical role in determining production efficiency.In this study,3D geometric models of 40/70 mesh ceramic particles and quartz sand proppant clusters were elaborated using computed tomography(CT)scanning.These models were used to develop a numerical simulation framework based on the lattice Boltzmann method(LBM),enabling the investigation of gas-water flow behavior within proppant-filled fractures under varying driving forces and surface tensions.Simulation results at a closure pressure of 15 MPa have revealed that ceramic particles exhibit a simpler and more porous internal structure than quartz sand of the same size.Under identical flow conditions,ceramic proppants demonstrate higher fluid replacement efficiency.Replacement efficiency increases with higher porosity,greater driving force,and lower surface tension.Furthermore,fluid displacement is strongly influenced by pore geometry:flow is faster in straighter and wider channels,with preferential movement through larger pores forming dominant flow paths.The replacement velocity exhibits a characteristic time evolution,initially rapid,then gradually decreasing,correlating positively with the development of these dominant channels.展开更多
AIM:To evaluate retinal hemoglobin oxygen saturation in myopic eyes by scanning laser ophthalmoscope(SLO)and to assess its correlations with different severity of myopia.METHODS:Sixty-one eyes from 61 patients were in...AIM:To evaluate retinal hemoglobin oxygen saturation in myopic eyes by scanning laser ophthalmoscope(SLO)and to assess its correlations with different severity of myopia.METHODS:Sixty-one eyes from 61 patients were included and subdivided into three groups according to their refractive errors:high myopia group[20 eyes,spherical equivalent(SE)≤-6 D];low and moderate myopia(22 eyes,-6.0<SE≤-0.5 D);normal(19 eyes,-0.5<SE<+0.5 D).All subjects underwent SLO imaging with dual lasers(532 nm and 633 nm).The oxygen saturations of hemoglobin in arteries(SO_(2)A)and veins(SO_(2)V),and their differences(SO_(2)AV)were estimated from the optical densities of the vessels on the images at the two wavelengths.Pearson’s or Spearman’s rank correlation coefficient were calculated to assess the correlation between retinal hemoglobin oxygen saturation and refractive error/axial length(AL).RESULTS:For the retinal oxygen saturation,the SO_(2)V in high myopia group(73.21%±21.42%)was significantly higher than that in normal group(55.81%±21.69%)and low and moderate myopia group(56.88%±13.83%,P<0.05).The SE was significantly correlated with SO_(2)A(r=-0.30)and SO_(2)V(r=-0.36;P<0.05),and AL was also significantly correlated with SO_(2)A(r=0.27)and SO_(2)V(r=0.30;P<0.05).No significant correlations were found between SO_(2)AV and SE and AL(P>0.05).CONCLUSION:SO_(2)A and SO_(2)V increased in more myopic eye based on SLO measurements.Further studies are warranted to investigate the changes of retinal hemoglobin oxygen saturation in myopia with different methods.展开更多
The assembly behaviors of two low-symmetric carboxylic acid molecules(50-(6-carboxynaphthalen-2-yl)-[1,10:30,100-triphenyl]-3,400,5-tricarboxylic acid(CTTA)and 30,50-bis(6-carboxynaphthalen-2-yl)-[1,10-biphenyl]-3,5-d...The assembly behaviors of two low-symmetric carboxylic acid molecules(50-(6-carboxynaphthalen-2-yl)-[1,10:30,100-triphenyl]-3,400,5-tricarboxylic acid(CTTA)and 30,50-bis(6-carboxynaphthalen-2-yl)-[1,10-biphenyl]-3,5-dicarboxylic acid(BCBDA))containing naphthalene rings on graphite surfaces have been investigated using scanning tunneling microscopy(STM).The transformation of nanostructures induced by the second components(EDA and PEBP-C4)have been also examined.Both CTTA and BCBDA molecules self-assemble at the 1-heptanoic acid(HA)/HOPG interface,forming porous network structures.The dimer represents the most elementary building unit due to the formation of double hydrogen bonds.Moreover,the flipping of naphthalene ring results in the isomerization of BCBDA molecule.The introduction of carboxylic acid derivative EDA disrupts the dimer,which subsequently undergoes a structural conformation to form a novel porous structure.Furthermore,upon the addition of pyridine derivative PEBP-C4,N–H⋯O hydrogen bonds are the dominant forces driving the three coassembled structures.We have also conducted density functional theory(DFT)calculations to determine the molecular conformation and analyze the mechanisms underlying the formation of nanostructures.展开更多
Gas-liquid two-phase flow in fractal porous media is pivotal for engineering applications,yet it remains challenging to be accurately characterized due to complex microstructure-flow interactions.This study establishe...Gas-liquid two-phase flow in fractal porous media is pivotal for engineering applications,yet it remains challenging to be accurately characterized due to complex microstructure-flow interactions.This study establishes a pore-scale numerical framework integratingMonte Carlo-generated fractal porousmedia with Volume of Fluid(VOF)simulations to unravel the coupling among pore distribution characterized by fractal dimension(Df),flow dynamics,and displacement efficiency.A pore-scale model based on the computed tomography(CT)microstructure of Berea sandstone is established,and the simulation results are compared with experimental data.Good agreement is found in phase distribution,breakthrough behavior,and flow path morphology,confirming the reliability of the numerical simulation method.Ten fractal porous media models with Df ranging from 1.25~1.7 were constructed using a Monte-Carlo approach.The gas-liquid two-phase flow dynamics was characterized using the VOF solver across gas injection rates of 0.05-5m/s,inwhich the time-resolved two-phase distribution patternswere systematically recorded.The results reveal that smaller fractal dimensions(Df=1.25~1.45)accelerate fingering breakthrough(peak velocity is 1.73 m/s at Df=1.45)due to a bimodal pore size distribution dominated by narrow channels.Increasing Df amplifies vorticity generation by about 3 times(eddy viscosity is 0.033 Pa⋅s at Df=1.7)through reduced interfacial curvature,while tortuosity-driven pressure differentials transition from sharp increases(0.4~6.3 Pa at Df=1.25~1.3)to inertial plateaus(4.8 Pa at Df=1.7).A nonlinear increase in equilibrium gas volume fraction(fav=0.692 at Df=1.7)emerges from residual gas saturation and turbulence-enhanced dispersion.This behavior is further modulated by flow velocity,with fav peaking at 0.72 under capillary-dominated conditions(0.05 m/s),but decreasing to 0.65 in the inertial regime(0.5 m/s).The work quantitatively links fractal topology to multiphase flow regimes,demonstrating the critical role of Df in governing preferential pathways,energy dissipation,and phase distribution.展开更多
Manipulating and braiding Majorana zero modes(MZM)are a critical step toward realizing topological quantum computing.The primary challenge is controlling the vortex,which hosts the MZM,within a superconducting film in...Manipulating and braiding Majorana zero modes(MZM)are a critical step toward realizing topological quantum computing.The primary challenge is controlling the vortex,which hosts the MZM,within a superconducting film in a spatially precise manner.To address this,we developed a magnetic force-based vortex control technology using the STM system with a self-designed four-electrode piezo-scanner tube and investigated vortex manipulation on the NbSe_(2) superconducting film.We employed ferromagnetic tips to control the movement of vortex array induced by the tip's remanent magnetism.A magnetic core solenoid device was integrated into the STM system and a strong magnetic tip demagnetization technique was developed,providing a viable technical solution for further enabling single vortex manipulation.展开更多
In photothermal power(solar energy)generation systems,purging residual molten salt from pipelines using highpressure gas poses a significant challenge,particularly in clearing the bottom of regulating valves.Ineffecti...In photothermal power(solar energy)generation systems,purging residual molten salt from pipelines using highpressure gas poses a significant challenge,particularly in clearing the bottom of regulating valves.Ineffective purging can lead to crystallization of the molten salt,resulting in blockages.To address this issue,understanding the gas-liquid two-phase flow dynamics during high-pressure gas purging is crucial.This study utilizes the Volume of Fluid(VOF)model and adaptive dynamic grids to simulate the gas-liquid two-phase flow during the purging process in a DN50 PN50 conventional molten salt regulating valve.Initially,the reliability of the CFD simulations is validated through comparisons with experimental data and findings from the literature.Subsequently,simulation experiments are conducted to analyze the effects of various factors,including purge flow rates,initial liquid accumulation masses,purge durations,and the profiles of the valve bottom flow channels.The results indicate that the purging process comprises four distinct stages:Initial violent surge stage,liquid discharge stage,liquid partial fallback stage,liquid dissipation stage.For an initial liquid height of 17 mm at the bottom of the valve,the critical purge flow rate lies between 3 and 5 m/s.Notably,the critical purge flow rate is independent of the initial liquid accumulation mass.As the purge gas flow rate increases,the volume of liquid discharged also increases.Beyond the critical purge flow rate,higher purge gas velocities lead to shorter purge durations.Interestingly,the residual liquid mass after purging remains unaffected by the initial liquid accumulation.Additionally,the flow channel profile at the bottom of the valve significantly influences both the critical purge speed and the efficiency of the purging process.展开更多
Mitochondria play a crucial role in the physiological functions and energy metabolism of neurons,which can help in the understanding of complex biochemical reactions associated with various neurodegenerative diseases....Mitochondria play a crucial role in the physiological functions and energy metabolism of neurons,which can help in the understanding of complex biochemical reactions associated with various neurodegenerative diseases.Neurons,being highly differentiated terminal cells,require a greater number of mitochondria than ordinary cells to generate significant amounts of ATP,which is necessary for the growth of differentiated neuronal structures like axons and dendrites and the transmission of electrical signals along neuronal axons.Advancements in imaging technology,electrophysiology,and fluorescence targeting labeling have facilitated the study of mitochondrial movements in neurons and axons.However,disordered mitochondrial movements can hinder their analysis and characterization.Thus,it becomes necessary to artificially control their transport.Here,we demonstrate the utilization of scanning optical tweezers(SOTs)on the stable trapping and precise transport of soma or axon of neurons and enable.The presented method provides an optical approach to the control of mitochondria or other organelles in complex and variable biological environment.展开更多
Polymer flooding is an important means of improving oil recovery and is widely used in Daqing,Xinjiang,and Shengli oilfields,China.Different from conventional injection media such as water and gas,viscoelastic polymer...Polymer flooding is an important means of improving oil recovery and is widely used in Daqing,Xinjiang,and Shengli oilfields,China.Different from conventional injection media such as water and gas,viscoelastic polymer solutions exhibit non-Newtonian and nonlinear flow behavior including shear thinning and shear thickening,polymer convection,diffusion,adsorption,retention,inaccessible pore volume,and reduced effective permeability.However,available well test model of polymer flooding wells generally simplifies these characteristics on pressure transient response,which may lead to inaccurate results.This work proposes a novel two-phase numerical well test model to better describe the polymer viscoelasticity and nonlinear flow behavior.Different influence factors that related to near-well blockage during polymer flooding process,including the degree of blockage(inner zone permeability),the extent of blockage(composite radius),and polymer flooding front radius are explored to investigate these impacts on bottom hole pressure responses.Results show that polymer viscoelasticity has a significant impact on the transitional flow segment of type curves,and the effects of near-well formation blockage and polymer concentration distribution on well test curves are very similar.Thus,to accurately interpret the degree of near-well blockage in injection wells,it is essential to first eliminate the influence of polymer viscoelasticity.Finally,a field case is comprehensively analyzed and discussed to illustrate the applicability of the proposed model.展开更多
基金supported by the National Key R&D Program(No.2023YFB3709900)the National Nature Science Foundation of China(No.U22A20171)+2 种基金China Baowu Low Carbon Metallurgy Innovation Foundation(No.BWLCF202315)the High Steel Center(HSC)at North China University of TechnologyUniversity of Science and Technology Beijing,China.
文摘The characteristics of nonmetallic inclusions formed during steel production have a significant influence on steel performance.In this paper,studies on inclusions using confocal scanning laser microscopy(CSLM)are reviewed and summarized,particularly the col-lision of various inclusions,dissolution of inclusions in liquid slag,and reactions between inclusions and steel.Solid inclusions exhibited a high collision tendency,whereas pure liquid inclusions exhibited minimal collisions because of the small attraction force induced by their<90°contact angle with molten steel.The collision of complex inclusions in molten steel was not included in the scope of this study and should be evaluated in future studies.Higher CaO/Al_(2)O_(3)and CaO/SiO_(2)ratios in liquid slag promoted the dissolution of Al_(2)O_(3)-based in-clusions.The formation of solid phases in the slag should be prevented to improve dissolution of inclusions.To accurately simulate the dissolution of inclusions in liquid slag,in-situ observation of the dissolution of inclusions at the steel-slag interface is necessary.Using a combination of CSLM and scanning electron microscopy-energy dispersive spectroscopy,the composition and morphological evolution of the inclusions during their modification by the dissolved elements in steel were observed and analyzed.Although the in-situ observa-tion of MnS and TiN precipitations has been widely studied,the in-situ observation of the evolution of oxide inclusions in steel during so-lidification and heating processes has rarely been reported.The effects of temperature,heating and cooling rates,and inclusion character-istics on the formation of acicular ferrites(AFs)have been widely studied.At a cooling rate of 3-5 K/s,the order of AF growth rate in-duced by different inclusions,as reported in literature,is Ti-O<Ti-Ca-Zr-Al-O<Mg-O<Ti-Zr-Al-O<Mn-Ti-Al-O<Ti-Al-O<Zr-Ti-Al-O.Further comprehensive experiments are required to investigate the quantitative relationship between the formation of AFs and inclusions.
基金supported by Independent Research Project of State Key Laboratory of Advanced Special Steel,Shanghai Key Laboratory of Advanced Ferrometallurgy,Shanghai University(SKLASS-2023-Z13)the Science and Technology Commission of Shanghai Municipality(No.19DZ2270200)+1 种基金A portion of the work was performed at US National High Magnetic Field Laboratory,which is supported by the National Science Foundation(Cooperative Agreement No.DMR-1157490 and DMR-1644779)the State of Florida.Thanks also to Mary Tyler for editing.
文摘The high-temperature dissolution behavior of primary carbides in samples taken from GCr15 continuous-casting bloom was observed in-situ by confocal laser scanning microscopy.Equations were fitted to the dissolution kinetics of primary carbides during either heating or soaking.Dissolution of carbides proceeded in three stages(fast→slow→faster)as either temperature or holding time was increased.During the heating process and during the first and third stages of the soaking process,the original size of the carbides determined the steepness of the slope,but during the middle(“slow”)stage of the soaking process,the slope remained zero.The initial size of the carbides varied greatly,but their final dissolution temperature fell within the narrow range of 1210-1235℃,and the holding time remained within 50 min.Fractal analysis was used to study the morphological characteristics of small and medium-sized carbides during the dissolution process.According to changes in the fractal dimension before and after soaking,the carbides tended to evolve towards a more regular morphology.
基金the National Natural Science Foundation of China (Nos. 42302143, 42172159)China Geological Survey Project (No. DD20211350)support from the G. Albert Shoemaker endowment
文摘Clayey-silt natural gas hydrate reservoirs in the South China Sea exhibit loose and unconsolidated structures, heterogeneous pore structures, high clay mineral contents, and strong hydrophilicity. These characteristics complicate the gas-water two-phase flow process in porous media following hydrate decomposition, posing challenges for efficient development. This study examines the transport response of clayey-silt reservoir samples from the Shenhu area using gas-water two-phase flow experiments and CT scanning to explore changes in pore structure, gas-water distribution, and relative permeability under varying flow conditions. The results indicate that pore heterogeneity significantly influences flow characteristics. Gas preferentially displaces water in larger pores, forming fracture-like pores, which serve as preferential flow channels for gas migration. The preferential flow channels enhance gas-phase permeability up to 19 times that of the water phase when fluid pressures exceed total stresses. However,small pores retain liquid, leading to a high residual water saturation of 0.561. CT imaging reveals that these hydro-fractures improve gas permeability but also confine gas flow to specific channels. Pore network analysis shows that gas injection expands the pore-throat network, enhancing connectivity and forming fracture-like pores. Residual water remains trapped in smaller pores and throats, while structural changes, including new fractures, improve gas flow pathways and overall connectivity. Relative permeability curves demonstrate a narrow gas-water cocurrent-flow zone, a right-shifted iso-permeability point and high reservoir capillary pressure, indicating a strong "water-blocking" effect. The findings suggest that optimizing reservoir stimulation techniques to enhance fracture formation, reduce residual water saturation, and improve gas flow capacity is critical for efficient hydrate reservoir development.
基金supported by National Natural Science Foundation of China(No.52176122).
文摘The centroid coordinate serves as a critical control parameter in motion systems,including aircraft,missiles,rockets,and drones,directly influencing their motion dynamics and control performance.Traditional methods for centroid measurement often necessitate custom equipment and specialized positioning devices,leading to high costs and limited accuracy.Here,we present a centroid measurement method that integrates 3D scanning technology,enabling accurate measurement of centroid across various types of objects without the need for specialized positioning fixtures.A theoretical framework for centroid measurement was established,which combined the principle of the multi-point weighing method with 3D scanning technology.The measurement accuracy was evaluated using a designed standard component.Experimental results demonstrate that the discrepancies between the theoretical and the measured centroid of a standard component with various materials and complex shapes in the X,Y,and Z directions are 0.003 mm,0.009 mm,and 0.105 mm,respectively,yielding a spatial deviation of 0.106 mm.Qualitative verification was conducted through experimental validation of three distinct types.They confirmed the reliability of the proposed method,which allowed for accurate centroid measurements of various products without requiring positioning fixtures.This advancement significantly broadened the applicability and scope of centroid measurement devices,offering new theoretical insights and methodologies for the measurement of complex parts and systems.
基金the financial support from the National Natural Science Foundation of China (No.42102127)the Postdoctoral Research Foundation of China (No.2024 M751860)。
文摘Cleat serves as the primary flow pathway for coalbed methane(CBM)and water.However,few studies consider the impact of local contact on two-phase flow within cleats.A visual generalized model of endogenous cleats was constructed based on microfluidics.A microscopic and mesoscopic observation technique was proposed to simultaneously capture gas-liquid interface morphology of pores and throat and the two-phase flow characteristics in entire cleat system.The local contact characteristics of cleats reduced absolute permeability,which resulted in a sharp increase in the starting pressure.The reduced gas flow capacity narrowed the co-infiltration area and decreased water saturation at the isotonic point in a hydrophilic environment.The increased local contact area of cleats weakened gas phase flow capacity and narrowed the co-infiltration area.Jumping events occurred in methane-water flow due to altered porosity caused by local contact in cleats.The distribution of residual phases changed the jumping direction on the micro-scale as well as the dominant channel on the mesoscale.Besides,jumping events caused additional energy dissipation,which was ignored in traditional two-phase flow models.This might contribute to the overestimation of relative permeability.The work provides new methods and insights for investigating unsaturated flow in complex porous media.
基金supported by the National Natural Science Foundation of China (Grant No. 12202204)the Natural Science Foundation of Jiangsu Province (Grant No. BK20220953)+1 种基金the Fundamental Research Funds for the Central Universitiesthe Science and Technology Association's Young Talent Nurturing Program of Jiangsu Province (Grant No. JSTJ-2024-004)
文摘In this study, the three-dimensional non-premixed two-phase kerosene/air rotating detonation engines with different isolator configurations and throat area ratios are simulated by the Eulerian-Lagrangian method. The effects of the divergence, straight, and convergence isolators on the rotating detonation wave dynamics and the upstream oblique shock wave propagation mechanism are analyzed. The differences in the rotating detonation wave behaviors between ground and flight operations are clarified.The results indicate that the propagation regimes of the upstream oblique shock wave depend on the isolator configurations and operation conditions. With a divergence isolator, the airflow is accelerated throughout the isolator and divergence section, leading to a maximum Mach number(~1.8) before the normal shock. The total pressure loss reaches the largest, and the detonation pressure drops. The upstream oblique shock wave can be suppressed within the divergence section with the divergence isolator.However, for the straight and convergence isolators, the airflow in the isolator with a larger ψ_(1)(0.3 and0.4) can suffer from the disturbance of the upstream oblique shock wave. The critical incident angle is around 39° at ground operation conditions. The upstream oblique shock wave tends to be suppressed when the engine operates under flight operation conditions. The critical pressure ratio β_(cr0) is found to be able to help in distinguishing the propagation regimes of the upstream oblique shock wave. Slightly below or above the β_(cr0) can obtain different marginal propagation results. The high-speed airflow in the divergence section affects the fuel droplet penetration distance, which deteriorates the reactant mixing and the detonation area. Significant detonation velocity deficits are observed and the maximum velocity deficit reaches 26%. The results indicate the engine channel design should adopt different isolator configurations based on the purpose of total pressure loss or disturbance suppression. This study can provide useful guidance for the channel design of a more complete two-phase rotating detonation engine.
基金supported by the National Key Research and Development Program of China(No.2022YFC3702000)the National Natural Science Foundation of China(No.52070169)the Project of Bureau of Science and Technology of Zhoushan,China(No.2022C41013).
文摘Two-phase partitioning bioreactors(TPPBs)have been widely used because they overcome the mass-transfer limitation of hydrophobic volatile organic compounds(VOCs)in waste gas biological treatments.Understanding the mechanisms of mass-transfer enhancement in TPPBs would enable efficient predictions for further industrial applications.In this study,influences of gradually increasing silicone oil ratio on the TPPB was explored,and a 94.35%reduction of the n-hexane partition coefficient was observed with 0.1 vol.%silicone,which increased to 80.7%along with a 40-fold removal efficiency enhancement in the stabilised removal period.The elimination capacity increased from 1.47 to 148.35 g/(m^(3)·h),i.e.a 101-fold increase compared with that of the single-phase reactors,when 10 vol.%(3 Critical Micelle Concentration)silicone oil was added.The significantly promoted partition coefficient was the main reason for the mass transfer enhancement,which covered the negative influences of the decreased total mass-transfer coefficient with increasing silicone oil volume ratio.The gradually rising stirring rate was benefit to the n-hexane removal,which became negative when the dominant resistance shifted from mass transfer to biodegradation.Moreover,a mass-transfer-reaction kinetic model of the TPPB was constructed based on the balance of n-hexane concentration,dissolved oxygen and biomass.Similar to the mechanism,the partition factor was predicted sensitive to the removal performance,and another five sensitive parameters were found simultaneously.This forecasting method enables the optimisation of TPPB performance and provides theoretical support for hydrophobic VOCs degradation.
基金supported by the National Natural Science Foundation of China(Grant Nos.52274339,52174321,52074186,and 52104337)Natural Science Foundation of Jiangsu Province(Grant No.BK20231317)China Baowu Low-Carbon Metallurgy Innovation Fund(Grant No.BWLCF202108).
文摘To investigate the nucleation behavior during the single-phased metallic solidification process,the commercial ultrapure ferritic stainless steels with no(Initial steel)and various melt treatments(R1,MR1,Y2,MY1,and M1 steels)were used to carry out the differential scanning colorimetry(DSC)and high-temperature confocal laser scanning microscope(HT-CLSM)experiments.Based on the results of DSC experiments,the equilibrium solidification process as well as the relationship among the critical undercooling degree(△T_(c)^(DSC)),latent heat of fusion/crystallization(△H_(f)/△H_(c)),equiaxed grain ratio(ER),and average grain size(△_(ave)^(ingot))was revealed.ER is increased with the decreasing△T_(c)^(DSC)and increasing△H_(f)/△H_(c);however,△_(ave)^(ingot)is decreased with them.Referring to the results of HT-CLSM experiments,the average sizes of micro-/macrostructures(d_(ave)/D_(ave)/)are decreased with the increasing cooling rate,as well as the difference between and apparent critical undercooling degree(△T_(c)^(CLSM))was revealed.The heterogeneous nucleation of the crystal nuclei occurs only if△T_(c)^(CLSM)>△T_(c)^(DSC).Combining with the interfacial wetting-lattice mismatch heterogeneous nucleation model,the dynamic mechanism of the metallic solidification was revealed.The as-cast grains of the melt-treated samples were obviously refined,owing to the much higher actual heterogeneous nucleation rates(I_(heter.,i))obtained through melt treatments,and the heterogeneous nucleation rates(I_(heter.,ij))for all samples are increased with the cooling rates,firmly confirming that the as-cast grains of each sample could be refined by the increasing cooling rates.
基金supported by the Beijing Municipal Science&Technology Commission(Z231100006123010).
文摘With the increasing miniaturization of systems and surging demand for power density,accurate prediction and control of two-phase flow pressure drop have become a core challenge restricting the performance of microchannel heat exchangers.Pressure drop,a critical hydraulic characteristic,serves as both a natural constraint for cooling systems and determines the power required to pump the working fluid through microchannels.This paper reviews the characteristics,prediction models,and optimization measures of two-phase flow pressure drop for low-boiling-point working fluids in microchannels.It systematically analyzes key influencing factors such as fluid physical properties,operating conditions,channel geometry,and flow patterns,and discusses the complex mechanisms of pressure drop under the coupling effect of multi-physical fields.Mainstream prediction models are reviewed:the homogeneous flow model simplifies calculations but shows large deviations at low quality;the separated flow model considers interphase interactions and can be applied to micro-scales after modification;the flow-pattern-based model performs zoned modeling but relies on subjective classification;machine learning improves prediction accuracy but faces the“black-box”problem.In terms of optimization,channel designs are improved through porous structures and micro-rib arrays,and flow rate distribution is optimized using splitters to balance pressure drop and heat transfer performance.This study provides theoretical support for microchannel thermal management in high-power-density devices.
基金supported by the National Natural Science Foundation of China(Grant No.11972194).
文摘By combining with an improved model on engraving process,a two-phase flow interior ballistic model has been proposed to accurately predict the flow and energy conversion behaviors of pyrotechnic actuators.Using computational fluid dynamics(CFD),the two-phase flow and piston engraving characteristics of a pyrotechnic actuator are investigated.Initially,the current model was utilized to examine the intricate,multi-dimensional flow,and energy conversion characteristics of the propellant grains and combustion gas within the pyrotechnic actuator chamber.It was discovered that the combustion gas on the wall's constant transition from potential to kinetic energy,along with the combined effect of the propellant motion,are what create the pressure oscillation within the chamber.Additionally,a numerical analysis was conducted to determine the impact of various parameters on the pressure oscillation and piston motion,including pyrotechnic charge,pyrotechnic particle size,and chamber structural dimension.The findings show that decreasing the pyrotechnic charge will lower the terminal velocity,while increasing and decreasing the pyrotechnic particle size will reduce the pressure oscillation in the chamber.The pyrotechnic particle size has minimal bearing on the terminal velocity.The results of this investigation offer a trustworthy forecasting instrument for comprehending and creating pyrotechnic actuator designs.
基金supported by the National Natural Science Foundation of China(22378350).
文摘The exosomes hold significant potential in disease diagnosis and therapeutic interventions.The objective of this study was to investigate the potential of aqueous two-phase systems(ATPSs)for the separation of bovine milk exosomes.The milk exosome partition behaviors and bovine milk separation were investigated,and the ATPSs and bovine milk whey addition was optimized.The optimal separation conditions were identified as 16%(mass)polyethylene glycol 4000,10%(mass)dipotassium phosphate,and 1%(mass)enzymatic hydrolysis bovine milk whey.During the separation process,bovine milk exosomes were predominantly enriched in the interphase,while protein impurities were primarily found in the bottom phase.The process yielded bovine milk exosomes of 2.0×10^(11)particles per ml whey with high purity(staining rate>90%,7.01×10^(10)particles per mg protein)and high uniformity(polydispersity index<0.03).The isolated exosomes were characterized and identified by transmission electron microscopy,zeta potential and size distribution.The results demonstrated aqueous two-phase extraction possesses a robust capability for the enrichment and separation of exosomes directly from bovine milk whey,presenting a novel approach for the large-scale isolation of exosomes.
基金Science Foundation for Distinguished Young Scholars 2020-JCJQ-ZQ-042 Intelligent and Bionic Spacecraft Thermal Control Technology Inspired by Tree Sap Transport Principle.
文摘As space technology advances,thermal control systems must effectively collect and dissipate heat from distributed,multi-source environments.Loop heat pipe is a highly reliable two-phase heat transfer component,but it has several limitations when addressing multi-source heat dissipation.Inspired by the transport and heat dissipation system of plants,large trees achieve stable and efficient liquid supply under the influence of two driving forces:capillary force during transpiration in the leaves(pull)and root pressure generated by osmotic pressure in the roots(push).The root pressure provides an effective liquid supply with a driving force exceeding 2 MPa,far greater than the driving force in conventional capillary-pumped two-phase loops.Research has shown that osmotic heat pipes offer a powerful driving force,and combining osmotic pressure with capillary force has significant advantages.Therefore,this paper designs a multi-evaporator,dual-drive two-phase loop,using both osmotic pressure and capillary force to solve the multi-source heat dissipation challenge.First,a transmembrane water flux model for the osmotic pressure-driven device was established to predict the maximum heat transfer capacity of the dual-drive two-phase loop.Then,an experimental setup for a multi-evaporator“osmotic pressure+capillary force”dual-drive two-phase loop was constructed,capable of transferring at least 235 W of power under a reverse gravity condition of 20 m.The study also analyzed the effects of reverse gravity height,heat load distribution among the three evaporators,startup sequence,and varying branch resistances on the performance of the dual-drive two-phase loop.
文摘Shale gas production involves complex gas-water two-phase flow,with flow patterns in proppant-filled fractures playing a critical role in determining production efficiency.In this study,3D geometric models of 40/70 mesh ceramic particles and quartz sand proppant clusters were elaborated using computed tomography(CT)scanning.These models were used to develop a numerical simulation framework based on the lattice Boltzmann method(LBM),enabling the investigation of gas-water flow behavior within proppant-filled fractures under varying driving forces and surface tensions.Simulation results at a closure pressure of 15 MPa have revealed that ceramic particles exhibit a simpler and more porous internal structure than quartz sand of the same size.Under identical flow conditions,ceramic proppants demonstrate higher fluid replacement efficiency.Replacement efficiency increases with higher porosity,greater driving force,and lower surface tension.Furthermore,fluid displacement is strongly influenced by pore geometry:flow is faster in straighter and wider channels,with preferential movement through larger pores forming dominant flow paths.The replacement velocity exhibits a characteristic time evolution,initially rapid,then gradually decreasing,correlating positively with the development of these dominant channels.
基金Supported by Shantou Science and Technology Project(No.190917155269927)2020 Li Ka Shing Foundation Cross-Disciplinary Research Grant(No.2020LKSFG06B).
文摘AIM:To evaluate retinal hemoglobin oxygen saturation in myopic eyes by scanning laser ophthalmoscope(SLO)and to assess its correlations with different severity of myopia.METHODS:Sixty-one eyes from 61 patients were included and subdivided into three groups according to their refractive errors:high myopia group[20 eyes,spherical equivalent(SE)≤-6 D];low and moderate myopia(22 eyes,-6.0<SE≤-0.5 D);normal(19 eyes,-0.5<SE<+0.5 D).All subjects underwent SLO imaging with dual lasers(532 nm and 633 nm).The oxygen saturations of hemoglobin in arteries(SO_(2)A)and veins(SO_(2)V),and their differences(SO_(2)AV)were estimated from the optical densities of the vessels on the images at the two wavelengths.Pearson’s or Spearman’s rank correlation coefficient were calculated to assess the correlation between retinal hemoglobin oxygen saturation and refractive error/axial length(AL).RESULTS:For the retinal oxygen saturation,the SO_(2)V in high myopia group(73.21%±21.42%)was significantly higher than that in normal group(55.81%±21.69%)and low and moderate myopia group(56.88%±13.83%,P<0.05).The SE was significantly correlated with SO_(2)A(r=-0.30)and SO_(2)V(r=-0.36;P<0.05),and AL was also significantly correlated with SO_(2)A(r=0.27)and SO_(2)V(r=0.30;P<0.05).No significant correlations were found between SO_(2)AV and SE and AL(P>0.05).CONCLUSION:SO_(2)A and SO_(2)V increased in more myopic eye based on SLO measurements.Further studies are warranted to investigate the changes of retinal hemoglobin oxygen saturation in myopia with different methods.
基金financially supported by the National Natural Science Foundation of China(No.22272039)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB36000000)+1 种基金the Youth Program of the Liaoning Education Department(No.LJKQZ20222280)the Jilin Chinese Academy of Sciences-Yanshen Technology Co.,Ltd.
文摘The assembly behaviors of two low-symmetric carboxylic acid molecules(50-(6-carboxynaphthalen-2-yl)-[1,10:30,100-triphenyl]-3,400,5-tricarboxylic acid(CTTA)and 30,50-bis(6-carboxynaphthalen-2-yl)-[1,10-biphenyl]-3,5-dicarboxylic acid(BCBDA))containing naphthalene rings on graphite surfaces have been investigated using scanning tunneling microscopy(STM).The transformation of nanostructures induced by the second components(EDA and PEBP-C4)have been also examined.Both CTTA and BCBDA molecules self-assemble at the 1-heptanoic acid(HA)/HOPG interface,forming porous network structures.The dimer represents the most elementary building unit due to the formation of double hydrogen bonds.Moreover,the flipping of naphthalene ring results in the isomerization of BCBDA molecule.The introduction of carboxylic acid derivative EDA disrupts the dimer,which subsequently undergoes a structural conformation to form a novel porous structure.Furthermore,upon the addition of pyridine derivative PEBP-C4,N–H⋯O hydrogen bonds are the dominant forces driving the three coassembled structures.We have also conducted density functional theory(DFT)calculations to determine the molecular conformation and analyze the mechanisms underlying the formation of nanostructures.
基金funded by the National Key R&D Program of China,China(Grant No.2023YFB4005500)National Natural Science Foundation of China,China(Grant Nos.52379113 and 52379114).
文摘Gas-liquid two-phase flow in fractal porous media is pivotal for engineering applications,yet it remains challenging to be accurately characterized due to complex microstructure-flow interactions.This study establishes a pore-scale numerical framework integratingMonte Carlo-generated fractal porousmedia with Volume of Fluid(VOF)simulations to unravel the coupling among pore distribution characterized by fractal dimension(Df),flow dynamics,and displacement efficiency.A pore-scale model based on the computed tomography(CT)microstructure of Berea sandstone is established,and the simulation results are compared with experimental data.Good agreement is found in phase distribution,breakthrough behavior,and flow path morphology,confirming the reliability of the numerical simulation method.Ten fractal porous media models with Df ranging from 1.25~1.7 were constructed using a Monte-Carlo approach.The gas-liquid two-phase flow dynamics was characterized using the VOF solver across gas injection rates of 0.05-5m/s,inwhich the time-resolved two-phase distribution patternswere systematically recorded.The results reveal that smaller fractal dimensions(Df=1.25~1.45)accelerate fingering breakthrough(peak velocity is 1.73 m/s at Df=1.45)due to a bimodal pore size distribution dominated by narrow channels.Increasing Df amplifies vorticity generation by about 3 times(eddy viscosity is 0.033 Pa⋅s at Df=1.7)through reduced interfacial curvature,while tortuosity-driven pressure differentials transition from sharp increases(0.4~6.3 Pa at Df=1.25~1.3)to inertial plateaus(4.8 Pa at Df=1.7).A nonlinear increase in equilibrium gas volume fraction(fav=0.692 at Df=1.7)emerges from residual gas saturation and turbulence-enhanced dispersion.This behavior is further modulated by flow velocity,with fav peaking at 0.72 under capillary-dominated conditions(0.05 m/s),but decreasing to 0.65 in the inertial regime(0.5 m/s).The work quantitatively links fractal topology to multiphase flow regimes,demonstrating the critical role of Df in governing preferential pathways,energy dissipation,and phase distribution.
基金Project supported by the National Key Research&Development Program of China(Grant Nos.2019YFA0308600 and 2020YFA0309000)the National Natural Science Foundation of China(Grant Nos.92365302,92065201,22325203,92265105,12074247,12174252,52102336)+2 种基金the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDB28000000)the Science and Technology Commission of Shanghai Municipality(Grant Nos.2019SHZDZX01,19JC1412701,20QA1405100,24LZ1401000,LZPY2024-04)financial support from the Innovation Program for Quantum Science and Technology(Grant No.2021ZD0302500)。
文摘Manipulating and braiding Majorana zero modes(MZM)are a critical step toward realizing topological quantum computing.The primary challenge is controlling the vortex,which hosts the MZM,within a superconducting film in a spatially precise manner.To address this,we developed a magnetic force-based vortex control technology using the STM system with a self-designed four-electrode piezo-scanner tube and investigated vortex manipulation on the NbSe_(2) superconducting film.We employed ferromagnetic tips to control the movement of vortex array induced by the tip's remanent magnetism.A magnetic core solenoid device was integrated into the STM system and a strong magnetic tip demagnetization technique was developed,providing a viable technical solution for further enabling single vortex manipulation.
文摘In photothermal power(solar energy)generation systems,purging residual molten salt from pipelines using highpressure gas poses a significant challenge,particularly in clearing the bottom of regulating valves.Ineffective purging can lead to crystallization of the molten salt,resulting in blockages.To address this issue,understanding the gas-liquid two-phase flow dynamics during high-pressure gas purging is crucial.This study utilizes the Volume of Fluid(VOF)model and adaptive dynamic grids to simulate the gas-liquid two-phase flow during the purging process in a DN50 PN50 conventional molten salt regulating valve.Initially,the reliability of the CFD simulations is validated through comparisons with experimental data and findings from the literature.Subsequently,simulation experiments are conducted to analyze the effects of various factors,including purge flow rates,initial liquid accumulation masses,purge durations,and the profiles of the valve bottom flow channels.The results indicate that the purging process comprises four distinct stages:Initial violent surge stage,liquid discharge stage,liquid partial fallback stage,liquid dissipation stage.For an initial liquid height of 17 mm at the bottom of the valve,the critical purge flow rate lies between 3 and 5 m/s.Notably,the critical purge flow rate is independent of the initial liquid accumulation mass.As the purge gas flow rate increases,the volume of liquid discharged also increases.Beyond the critical purge flow rate,higher purge gas velocities lead to shorter purge durations.Interestingly,the residual liquid mass after purging remains unaffected by the initial liquid accumulation.Additionally,the flow channel profile at the bottom of the valve significantly influences both the critical purge speed and the efficiency of the purging process.
基金supported by the National Natural Science Foundation of China(No.62135005)National Key Research and Development Program of China(No.2022YFA1206300)+4 种基金Guangdong Basic and Applied Basic Research Foundation(No.2021B1515020046)the Open Project Program of Wuhan National Laboratory for Optoelectronics(No.2020WNLOKF021)China National Postdoctoral Program for Innovative Talents(No.BX20220133)China Postdoctoral Science Foundation(No.2022M721342)the Outstanding Innovative Talents Cultivation Funded Programs for Doctoral Students of Jinan University(No.2022CXB012)。
文摘Mitochondria play a crucial role in the physiological functions and energy metabolism of neurons,which can help in the understanding of complex biochemical reactions associated with various neurodegenerative diseases.Neurons,being highly differentiated terminal cells,require a greater number of mitochondria than ordinary cells to generate significant amounts of ATP,which is necessary for the growth of differentiated neuronal structures like axons and dendrites and the transmission of electrical signals along neuronal axons.Advancements in imaging technology,electrophysiology,and fluorescence targeting labeling have facilitated the study of mitochondrial movements in neurons and axons.However,disordered mitochondrial movements can hinder their analysis and characterization.Thus,it becomes necessary to artificially control their transport.Here,we demonstrate the utilization of scanning optical tweezers(SOTs)on the stable trapping and precise transport of soma or axon of neurons and enable.The presented method provides an optical approach to the control of mitochondria or other organelles in complex and variable biological environment.
基金supported by the National Natural Science Foundation of China(52104049)the Young Elite Scientist Sponsorship Program by Beijing Association for Science and Technology(BYESS2023262)。
文摘Polymer flooding is an important means of improving oil recovery and is widely used in Daqing,Xinjiang,and Shengli oilfields,China.Different from conventional injection media such as water and gas,viscoelastic polymer solutions exhibit non-Newtonian and nonlinear flow behavior including shear thinning and shear thickening,polymer convection,diffusion,adsorption,retention,inaccessible pore volume,and reduced effective permeability.However,available well test model of polymer flooding wells generally simplifies these characteristics on pressure transient response,which may lead to inaccurate results.This work proposes a novel two-phase numerical well test model to better describe the polymer viscoelasticity and nonlinear flow behavior.Different influence factors that related to near-well blockage during polymer flooding process,including the degree of blockage(inner zone permeability),the extent of blockage(composite radius),and polymer flooding front radius are explored to investigate these impacts on bottom hole pressure responses.Results show that polymer viscoelasticity has a significant impact on the transitional flow segment of type curves,and the effects of near-well formation blockage and polymer concentration distribution on well test curves are very similar.Thus,to accurately interpret the degree of near-well blockage in injection wells,it is essential to first eliminate the influence of polymer viscoelasticity.Finally,a field case is comprehensively analyzed and discussed to illustrate the applicability of the proposed model.
