期刊文献+
共找到5篇文章
< 1 >
每页显示 20 50 100
Twinkle突变导致Perrault综合征的研究进展 被引量:1
1
作者 田国帅 董文吉 +1 位作者 汪伟 张业 《生命科学》 CSCD 北大核心 2020年第2期139-142,共4页
Twinkle基因编码蛋白TWINKLE可进入线粒体内参与复制体的组成,维持线粒体DNA数目的稳定。Perrault综合征作为一种罕见的常染色体隐性遗传病,可由Twinkle突变导致,目前该疾病暂无全面的诊断方法和有效的治疗手段。现简要概述了Twinkle突... Twinkle基因编码蛋白TWINKLE可进入线粒体内参与复制体的组成,维持线粒体DNA数目的稳定。Perrault综合征作为一种罕见的常染色体隐性遗传病,可由Twinkle突变导致,目前该疾病暂无全面的诊断方法和有效的治疗手段。现简要概述了Twinkle突变导致Perrault综合征的研究进展。 展开更多
关键词 twinkle Perrault综合征 线粒体DNA
原文传递
陌生人社交,别用它来约X——twinkle
2
作者 维恩 《计算机应用文摘》 2015年第22期50-50,共1页
提起陌生人社交应用,很多人第一时间会想到《陌陌》,紧接着就想到了约X。的确,《陌陌》的成功让陌生人交友的概念在国内普及开来,同时也为它打上不太光彩的负面标签。难道所有的陌生人社交APP都只能拿来约个什么?也不尽然,今天我... 提起陌生人社交应用,很多人第一时间会想到《陌陌》,紧接着就想到了约X。的确,《陌陌》的成功让陌生人交友的概念在国内普及开来,同时也为它打上不太光彩的负面标签。难道所有的陌生人社交APP都只能拿来约个什么?也不尽然,今天我们给大家带来的twinkle就不是干这个的哦! 展开更多
关键词 twinkle APP 社交应用 软件
在线阅读 下载PDF
From Coal to Solar
3
作者 YAN YING WANG RUYING 《China Today》 2025年第6期34-36,共3页
Shanxi,China’s leading coal-mining province,is feeding more green power into the national grid,heralding an era of cleaner and more sustainable energy.AT the national demonstration base of advanced photovoltaic(PV)te... Shanxi,China’s leading coal-mining province,is feeding more green power into the national grid,heralding an era of cleaner and more sustainable energy.AT the national demonstration base of advanced photovoltaic(PV)technology in Datong City,Shangxi Province-the largest coal producer in China,rows upon rows of solar panels glitter in the sunlight,resembling a twinkling blue ocean. 展开更多
关键词 SOLAR green power SHANXI twinkling blue ocean photovoltaic technology solar panels COAL cleaner more sustainable energyat
在线阅读 下载PDF
Diagnostic value ultrasound signs of stones less than or equal to 10 mm and clinicoradiological variants of ureteric colic
4
作者 Denis V.Krakhotkin Volodymyr A.Chernylovskyi +5 位作者 Kemal Sarica Arman Tsaturyan Evangelos Liatsikos Jurijus Makevicius Nikolay Yu Iglovikov Dmitry N.Pikhovkin 《Asian Journal of Urology》 CSCD 2023年第1期39-49,共11页
Objective:To determine the diagnostic value of ultrasound signs of urinary stones less than or equal to 10 mm and to determine clinico-radiological variants of ureteric colic.Methods:A total of 455 ultrasound investig... Objective:To determine the diagnostic value of ultrasound signs of urinary stones less than or equal to 10 mm and to determine clinico-radiological variants of ureteric colic.Methods:A total of 455 ultrasound investigations were performed in patients referring to emergency department with urolithiasis and symptoms suspected of ureteric colic between January 2021 and May 2021.In addition to microscopic evaluation of urine sediment to detect different crystals and non-contrast spiral computed tomography to detect stones,B-mode and color Doppler sonography was performed to assess the presence of acoustic shadow(AS)and twinkle artifacts(TA)as possible signs of stone(s)in ureter.Results:While the sensitivity and specificity of AS and TA were higher than 90%in patients with stones greater than 5 mm;positive prognostic values of these parameters were found to be extremely low for stones with sizes of 1-3 mm with specificity and sensitivity values not exceeding 53%.The sensitivity and specificity of AS and TA in the upper and lower ureters were higher for stones greater than or equal to 5 than for compared to those less than 5 mm.At the same time,the diagnostic values of TA and AS for middle ureter stones were very limited.The most prevalent clinico-radiological variants of ureteric colic were types I,III,and V being observed in 39%,28% and 21% cases,respectively.Conclusion:Our results demonstrate that TA and AS parameters seem to have a very low sensitivity and specificity in the diagnosis of urinary stones less than 5 mm.The diagnostic value of TA and AS increase significantly in stones greater than or equal to 5 mm.Therefore,clinicians need to be very careful for overestimating the diagnostic values of TA and AS for stones less than 5 mm and non-contrast spiral computed tomography must be the method of choice for patients presenting to emergency department with ureteric colic. 展开更多
关键词 Ureteric colic UROLITHIASIS ULTRASOUND twinkle artifact Non-contrast computed tomography
暂未订购
A Genetic Algorithm with Weighted Average Normally-Distributed Arithmetic Crossover and Twinkling
5
作者 George S. Ladkany Mohamed B. Trabia 《Applied Mathematics》 2012年第10期1220-1235,共16页
Genetic algorithms have been extensively used as a global optimization tool. These algorithms, however, suffer from their generally slow convergence rates. This paper proposes two approaches to address this limitation... Genetic algorithms have been extensively used as a global optimization tool. These algorithms, however, suffer from their generally slow convergence rates. This paper proposes two approaches to address this limitation. First, a new crossover technique, the weighted average normally-distributed arithmetic crossover (NADX), is introduced to enhance the rate of convergence. Second, twinkling is incorporated within the crossover phase of the genetic algorithms. Twinkling is a controlled random deviation that allows only a subset of the design variables to undergo the decisions of an optimization algorithm while maintaining the remaining variable values. Two twinkling genetic algorithms are proposed. The proposed algorithmsare compared to simple genetic algorithms by using various mathematical and engineering design test problems. The results show that twinkling genetic algorithms have the ability to consistently reach known global minima, rather than nearby sub-optimal points, and are able to do this with competitive rates of convergence. 展开更多
关键词 GENETIC ALGORITHMS CROSSOVER TECHNIQUES Twinkling Engineering Design GLOBAL Optimization
暂未订购
上一页 1 下一页 到第
使用帮助 返回顶部