BACKGROUND Congenital tufting enteropathy(CTE)is a rare cause of diarrhea in children.However,it can result in early-onset of chronic diarrhea and failure to thrive.Children with this disease have to depend on total p...BACKGROUND Congenital tufting enteropathy(CTE)is a rare cause of diarrhea in children.However,it can result in early-onset of chronic diarrhea and failure to thrive.Children with this disease have to depend on total parenteral nutrition(TPN),and eventually small intestine transplantation.The epithelial cell adhesion molecule(EPCAM)gene was identified to be associated with CTE.Here,we present a case of an infant with CTE due to a mutation not reported in the literature before.CASE SUMMARY A 1-year and 7-mo infant boy exhibited intractable watery diarrhea and mushy stool within 1 wk after birth,for which he had required medical treatment and hospitalization several times.His sister presented similar symptoms and died at the age of two.On admission,his body weight was 5700 g(-4.8 SDS)and measured 66 cm(-5.4 SDS)in height.Meanwhile,he cannot speak or climb.He exhibited mild anemia,hypocalcemia,hypomagnesemia,and an infection in the upper respiratory tract.Microvilli sparse and vacuolar degeneration of epithelial cells were reported by small intestine biopsy.Whole-exome sequencing showed a novel homozygous splice mutation(c.657+1[IVS6]G>A)in the EPCAM gene.He was treated with TPN and recombinant human growth hormone.After 2 mo,his body weight was up to 8500 g and he has been waiting for small bowel transplantation.CONCLUSION CTE is rare but fatal.Patients with CTE require rapid diagnosis and therapy to improve their survival.展开更多
The dynamic performance of the coupling shaft system in a carpet tufting machine is the most critical factor affecting the carpet tufting machine's efficiency,and the product quality of the tufted carpet. To deter...The dynamic performance of the coupling shaft system in a carpet tufting machine is the most critical factor affecting the carpet tufting machine's efficiency,and the product quality of the tufted carpet. To determine how to avoid resonance produced by the coupling shaft system's vibration during the weaving process,the dynamic performance of a coupling shaft system in a carpet tufting machine was analyzed. Focusing on a DHGN801D-400 carpet tufting machine,a dynamic model of coupling shaft system was established by utilizing transfer matrix methodology. On the basis of this model,the natural frequencies and mode shapes of the coupling shaft system were obtained through simulations. The correctness of the theoretical model and the dynamic performance of the coupling shaft system were validated by experiments. The first order natural frequency of the coupling shaft system was close to 600 r / min. A conclusion can thus be drawn that operating the carpet tufting machine near this speed should be avoided as much as possible.展开更多
In order to achieve high speed of tufting machine,the oval gear is used as the transmission mechanism between the main shaft and the slave shaft. And then,mathematical model of tufting machine spindle system is establ...In order to achieve high speed of tufting machine,the oval gear is used as the transmission mechanism between the main shaft and the slave shaft. And then,mathematical model of tufting machine spindle system is established by transfer matrix method.Finally,the dynamic reaction force of the connection and the unbalanced response of the joint between the general tufting machine and the improved spindle system are studied by using Matlab numerical simulation. The analysis results showthat when the spindle speed reaches 1 000 r/min, the dynamic reaction force of the improved spindle system at the joint is far less than that of the general tufting machine,and the unbalanced response is reduced from 0. 22 mm to 0. 10 mm.展开更多
In view of the lack of research on the information model of tufting carpet machine in China,an information modeling method based on Object Linking and Embedding for Process Control Unified Architecture(OPC UA)framewor...In view of the lack of research on the information model of tufting carpet machine in China,an information modeling method based on Object Linking and Embedding for Process Control Unified Architecture(OPC UA)framework was proposed to solve the problem of“information island”caused by the differentiated data interface between heterogeneous equipment and system in tufting carpet machine workshop.This paper established an information model of tufting carpet machine based on analyzing the system architecture,workshop equipment composition and information flow of the workshop,combined with the OPC UA information modeling specification.Subsequently,the OPC UA protocol is used to instantiate and map the information model,and the OPC UA server is developed.Finally,the practicability of tufting carpet machine information model under the OPC UA framework and the feasibility of realizing the information interconnection of heterogeneous devices in the tufting carpet machine digital workshop are verified.On this basis,the cloud and remote access to the underlying device data are realized.The application of this information model and information integration scheme in actual production explores and practices the application of OPC UA technology in the digital workshop of tufting carpet machine.展开更多
The olfactory bulb(OB)is the first relay station in the olfactory system and functions as a crucial hub.It can represent odor information precisely and accurately in an ever-changing environment.As the only output neu...The olfactory bulb(OB)is the first relay station in the olfactory system and functions as a crucial hub.It can represent odor information precisely and accurately in an ever-changing environment.As the only output neurons in the OB,mitral/tufted cells encode information such as odor identity and concentration.Recently,the neural strategies and mechanisms underlying odor representation and encoding in the OB have been investigated extensively.Here we review the main progress on this topic.We first review the neurons and circuits involved in odor representation,including the different cell types in the OB and the neural circuits within and beyond the OB.We will then discuss how two different coding strategies—spatial coding and temporal coding—work in the rodent OB.Finally,we discuss potential future directions for this research topic.Overall,this review provides a comprehensive description of our current understanding of how odor information is represented and encoded by mitral/tufted cells in the OB.展开更多
After a review of the tufting industry’s development, and a brief introduction to available systems for producing patterned tufted carpets, the principle of ICN (Individually Controlled Needle) and the related advanc...After a review of the tufting industry’s development, and a brief introduction to available systems for producing patterned tufted carpets, the principle of ICN (Individually Controlled Needle) and the related advanced tufting technology Col-ortec are presented. Finally, Colortec machine, Axminster weaving machine, and Wilton loom are compared. It is believed that the Cobble Colortec machine is a significant jump forward in the tufted carpets industry as it now allows access to all major carpet markets in a competitive fashion.展开更多
In the carpet tufting machine,feed rollers are used to guide the yarns positively.After deducing the general Euler formula of yarn tension under positive guide of rollers,a conclusion is got that the tension of yarns ...In the carpet tufting machine,feed rollers are used to guide the yarns positively.After deducing the general Euler formula of yarn tension under positive guide of rollers,a conclusion is got that the tension of yarns at the output side of each roller tends to decrease one by one.Afterwards,a computing formula of wrap angle of yarn passing through the feed roller is deduced by application of triangle geometry method.By analyzing the effect of each parameter on the yarn tension,values of the space between rollers and the roller diameter are proposed for design reference,and relations between the yarn tension and the two key parameters,the friction coefficient of roller surface and the speed of rollers,are illustrated in detail.Consequently,a policy is drawn out to control the yarn tension.The results of this paper provide not only theory foundation for empirical settings of the operational parameters of tufting machine,but also theory support for further research on yarn tension-control methods.展开更多
A new type of rare earth elements （REEs） deposit was discovered from the gaolinite mudstone in the weathering crust of Permian basalt, Bijie region, western Guizhou, China. It contained ∑RE2O3 0.065%-1.086%. This t...A new type of rare earth elements （REEs） deposit was discovered from the gaolinite mudstone in the weathering crust of Permian basalt, Bijie region, western Guizhou, China. It contained ∑RE2O3 0.065%-1.086%. This type of REEs deposit was widely distributed with steady horizon and thickness of 3-4 m. The ore-bearing weathering crust （kaolinite） of the three discovered REEs deposits belonged to the third episode of the Emeishan basalt eruption. The new type of REEs deposit was suggested that basalt （tuff） weathering could lead to the enrichment of the rare earth elements. Therefore, it is of important economic significance to explore REEs deposits in the weathering crust of basalt （tuffs） in Yunnan, Guizhou, and Sichuan Provinces.展开更多
Responses of 302 mitral/tufted (M/T) cells in the olfactory bulb were recorded from 42 anesthetized freely breathing rats using a 16-channel microwire electrode array.Saturated vapors of four pure chemicals,anisole,ca...Responses of 302 mitral/tufted (M/T) cells in the olfactory bulb were recorded from 42 anesthetized freely breathing rats using a 16-channel microwire electrode array.Saturated vapors of four pure chemicals,anisole,carvone,citral and isoamyl acetate were applied.After aligning spike trains to the initial phase of the inhalation after odor onset,the responses of M/T cells showed transient temporal features including excitatory and inhibitory patterns.Both odor-evoked patterns indicated that mammals recognize odors within a short respiration cycle after odor stimulus.Due to the small amount of information received from a single cell,we pooled results from all responsive M/T cells to study the ensemble activity.The firing rates of the cell ensembles were computed over 100 ms bins and population vectors were constructed.The high dimension vectors were condensed into three dimensions for visualization using principal component analysis.The trajectories of both excitatory and inhibitory cell ensembles displayed strong dynamics during odor stimulation.The distances among cluster centers were enlarged compared to those of the resting state.Thus,we presumed that pictures of odor information sent to higher brain regions were depicted and odor discrimination was completed within the first breathing cycle.展开更多
基金Key Research and Development Program of Zhejiang Province,China,No.2020C03121。
文摘BACKGROUND Congenital tufting enteropathy(CTE)is a rare cause of diarrhea in children.However,it can result in early-onset of chronic diarrhea and failure to thrive.Children with this disease have to depend on total parenteral nutrition(TPN),and eventually small intestine transplantation.The epithelial cell adhesion molecule(EPCAM)gene was identified to be associated with CTE.Here,we present a case of an infant with CTE due to a mutation not reported in the literature before.CASE SUMMARY A 1-year and 7-mo infant boy exhibited intractable watery diarrhea and mushy stool within 1 wk after birth,for which he had required medical treatment and hospitalization several times.His sister presented similar symptoms and died at the age of two.On admission,his body weight was 5700 g(-4.8 SDS)and measured 66 cm(-5.4 SDS)in height.Meanwhile,he cannot speak or climb.He exhibited mild anemia,hypocalcemia,hypomagnesemia,and an infection in the upper respiratory tract.Microvilli sparse and vacuolar degeneration of epithelial cells were reported by small intestine biopsy.Whole-exome sequencing showed a novel homozygous splice mutation(c.657+1[IVS6]G>A)in the EPCAM gene.He was treated with TPN and recombinant human growth hormone.After 2 mo,his body weight was up to 8500 g and he has been waiting for small bowel transplantation.CONCLUSION CTE is rare but fatal.Patients with CTE require rapid diagnosis and therapy to improve their survival.
基金National Natural Science Foundation of China(No.51175075)the Research and Innovation Project of Shanghai Municipal Education Commission,China(No.15ZZ034)
文摘The dynamic performance of the coupling shaft system in a carpet tufting machine is the most critical factor affecting the carpet tufting machine's efficiency,and the product quality of the tufted carpet. To determine how to avoid resonance produced by the coupling shaft system's vibration during the weaving process,the dynamic performance of a coupling shaft system in a carpet tufting machine was analyzed. Focusing on a DHGN801D-400 carpet tufting machine,a dynamic model of coupling shaft system was established by utilizing transfer matrix methodology. On the basis of this model,the natural frequencies and mode shapes of the coupling shaft system were obtained through simulations. The correctness of the theoretical model and the dynamic performance of the coupling shaft system were validated by experiments. The first order natural frequency of the coupling shaft system was close to 600 r / min. A conclusion can thus be drawn that operating the carpet tufting machine near this speed should be avoided as much as possible.
文摘In order to achieve high speed of tufting machine,the oval gear is used as the transmission mechanism between the main shaft and the slave shaft. And then,mathematical model of tufting machine spindle system is established by transfer matrix method.Finally,the dynamic reaction force of the connection and the unbalanced response of the joint between the general tufting machine and the improved spindle system are studied by using Matlab numerical simulation. The analysis results showthat when the spindle speed reaches 1 000 r/min, the dynamic reaction force of the improved spindle system at the joint is far less than that of the general tufting machine,and the unbalanced response is reduced from 0. 22 mm to 0. 10 mm.
文摘In view of the lack of research on the information model of tufting carpet machine in China,an information modeling method based on Object Linking and Embedding for Process Control Unified Architecture(OPC UA)framework was proposed to solve the problem of“information island”caused by the differentiated data interface between heterogeneous equipment and system in tufting carpet machine workshop.This paper established an information model of tufting carpet machine based on analyzing the system architecture,workshop equipment composition and information flow of the workshop,combined with the OPC UA information modeling specification.Subsequently,the OPC UA protocol is used to instantiate and map the information model,and the OPC UA server is developed.Finally,the practicability of tufting carpet machine information model under the OPC UA framework and the feasibility of realizing the information interconnection of heterogeneous devices in the tufting carpet machine digital workshop are verified.On this basis,the cloud and remote access to the underlying device data are realized.The application of this information model and information integration scheme in actual production explores and practices the application of OPC UA technology in the digital workshop of tufting carpet machine.
基金supported by the National Natural Science Foundation of China(Nos.32271055 and 32070995)the Jiangsu Province Innovative and Entrepreneurial Team Program,and the Guangdong Medical University(No.GDMUB2022048),China.
文摘The olfactory bulb(OB)is the first relay station in the olfactory system and functions as a crucial hub.It can represent odor information precisely and accurately in an ever-changing environment.As the only output neurons in the OB,mitral/tufted cells encode information such as odor identity and concentration.Recently,the neural strategies and mechanisms underlying odor representation and encoding in the OB have been investigated extensively.Here we review the main progress on this topic.We first review the neurons and circuits involved in odor representation,including the different cell types in the OB and the neural circuits within and beyond the OB.We will then discuss how two different coding strategies—spatial coding and temporal coding—work in the rodent OB.Finally,we discuss potential future directions for this research topic.Overall,this review provides a comprehensive description of our current understanding of how odor information is represented and encoded by mitral/tufted cells in the OB.
文摘After a review of the tufting industry’s development, and a brief introduction to available systems for producing patterned tufted carpets, the principle of ICN (Individually Controlled Needle) and the related advanced tufting technology Col-ortec are presented. Finally, Colortec machine, Axminster weaving machine, and Wilton loom are compared. It is believed that the Cobble Colortec machine is a significant jump forward in the tufted carpets industry as it now allows access to all major carpet markets in a competitive fashion.
文摘In the carpet tufting machine,feed rollers are used to guide the yarns positively.After deducing the general Euler formula of yarn tension under positive guide of rollers,a conclusion is got that the tension of yarns at the output side of each roller tends to decrease one by one.Afterwards,a computing formula of wrap angle of yarn passing through the feed roller is deduced by application of triangle geometry method.By analyzing the effect of each parameter on the yarn tension,values of the space between rollers and the roller diameter are proposed for design reference,and relations between the yarn tension and the two key parameters,the friction coefficient of roller surface and the speed of rollers,are illustrated in detail.Consequently,a policy is drawn out to control the yarn tension.The results of this paper provide not only theory foundation for empirical settings of the operational parameters of tufting machine,but also theory support for further research on yarn tension-control methods.
基金the Major State Basic Research Development Program of China (2006CB403202)the Doctoral Discipline Foundation of Guizhou University
文摘A new type of rare earth elements （REEs） deposit was discovered from the gaolinite mudstone in the weathering crust of Permian basalt, Bijie region, western Guizhou, China. It contained ∑RE2O3 0.065%-1.086%. This type of REEs deposit was widely distributed with steady horizon and thickness of 3-4 m. The ore-bearing weathering crust （kaolinite） of the three discovered REEs deposits belonged to the third episode of the Emeishan basalt eruption. The new type of REEs deposit was suggested that basalt （tuff） weathering could lead to the enrichment of the rare earth elements. Therefore, it is of important economic significance to explore REEs deposits in the weathering crust of basalt （tuffs） in Yunnan, Guizhou, and Sichuan Provinces.
基金Project (Nos. 30970765 and 81027003) supported by the National Natural Science Foundation of China
文摘Responses of 302 mitral/tufted (M/T) cells in the olfactory bulb were recorded from 42 anesthetized freely breathing rats using a 16-channel microwire electrode array.Saturated vapors of four pure chemicals,anisole,carvone,citral and isoamyl acetate were applied.After aligning spike trains to the initial phase of the inhalation after odor onset,the responses of M/T cells showed transient temporal features including excitatory and inhibitory patterns.Both odor-evoked patterns indicated that mammals recognize odors within a short respiration cycle after odor stimulus.Due to the small amount of information received from a single cell,we pooled results from all responsive M/T cells to study the ensemble activity.The firing rates of the cell ensembles were computed over 100 ms bins and population vectors were constructed.The high dimension vectors were condensed into three dimensions for visualization using principal component analysis.The trajectories of both excitatory and inhibitory cell ensembles displayed strong dynamics during odor stimulation.The distances among cluster centers were enlarged compared to those of the resting state.Thus,we presumed that pictures of odor information sent to higher brain regions were depicted and odor discrimination was completed within the first breathing cycle.
