Dear Editor,I am Dr.Tian-Wei Qian,from Shanghai General Hospital,Shanghai,China.I write to present one case report of tuberculosis（TB）-associated uveitis after corticosteroid treatment for Vogt-Koyanagi-Harada（VKH...Dear Editor,I am Dr.Tian-Wei Qian,from Shanghai General Hospital,Shanghai,China.I write to present one case report of tuberculosis（TB）-associated uveitis after corticosteroid treatment for Vogt-Koyanagi-Harada（VKH）disease.展开更多
Tuberculosis(TB)significantly increases the risk of developing chronic obstructive pulmonary disease(COPD),po-sitioning TB-associated COPD(TB-COPD)as a distinct category within the spectrum of respiratory diseases pre...Tuberculosis(TB)significantly increases the risk of developing chronic obstructive pulmonary disease(COPD),po-sitioning TB-associated COPD(TB-COPD)as a distinct category within the spectrum of respiratory diseases preva-lent,especially in low-and middle-income countries.This condition results from the body’s immune response to TB,leading to prolonged inflammation and consequent persistent lung damage.Diagnostic approaches,par-ticularly post-bronchodilator spirometry,are vital for identifying airflow obstruction and confirming TB-COPD.Furthermore,exploring potential biomarkers is crucial for a deeper insight into the pathogenesis of TB-COPD and the improvement of treatment strategies.Currently,this condition is primarily managed using inhaled bron-chodilators,with cautious use of inhaled corticosteroids advised owing to the increased risk of developing TB.This review delves into the epidemiology,clinical manifestations,pulmonary function,and imaging character-istics of TB-COPD,scrutinizing current and prospective biomarkers and therapeutic strategies.Furthermore,it underscores the necessity for focused research to bridge the knowledge and treatment gaps in this complex con-dition.展开更多
文摘Dear Editor,I am Dr.Tian-Wei Qian,from Shanghai General Hospital,Shanghai,China.I write to present one case report of tuberculosis（TB）-associated uveitis after corticosteroid treatment for Vogt-Koyanagi-Harada（VKH）disease.
基金supported by the National Natural Science Foundation of China(Nos.81400041,8217010845)Capital’s Funds for Health Improvement and Research(No.2022-2G-40910)+1 种基金Key Clinical Projects of Peking University Third Hospital(No.BYSYZD2022014)Peking University Medicine Fund of Fostering Young Scholars’Scientific&Technological Innovation(No.BMU2024YFJHPY014)supported by Fundamental Research Funds for the Central Universities.The funding bodies had no role in the design and writing of the manuscript。
文摘Tuberculosis(TB)significantly increases the risk of developing chronic obstructive pulmonary disease(COPD),po-sitioning TB-associated COPD(TB-COPD)as a distinct category within the spectrum of respiratory diseases preva-lent,especially in low-and middle-income countries.This condition results from the body’s immune response to TB,leading to prolonged inflammation and consequent persistent lung damage.Diagnostic approaches,par-ticularly post-bronchodilator spirometry,are vital for identifying airflow obstruction and confirming TB-COPD.Furthermore,exploring potential biomarkers is crucial for a deeper insight into the pathogenesis of TB-COPD and the improvement of treatment strategies.Currently,this condition is primarily managed using inhaled bron-chodilators,with cautious use of inhaled corticosteroids advised owing to the increased risk of developing TB.This review delves into the epidemiology,clinical manifestations,pulmonary function,and imaging character-istics of TB-COPD,scrutinizing current and prospective biomarkers and therapeutic strategies.Furthermore,it underscores the necessity for focused research to bridge the knowledge and treatment gaps in this complex con-dition.
