Dear Editor： The emergence of multidrug-resistant tuberculosis （MDR-TB） is bringing new challenges. MDR-TB is caused by Mycobacterium tuberculosis （M. tuberculosis） that is resistant to isoniazid and rifampicin,...Dear Editor： The emergence of multidrug-resistant tuberculosis （MDR-TB） is bringing new challenges. MDR-TB is caused by Mycobacterium tuberculosis （M. tuberculosis） that is resistant to isoniazid and rifampicin, with or with- out resistance to other anti-tuberculosis drugs. Approximately 450,000 people developed MDR-TB worldwide in 2012 and an estimated 170,000 people died from the disease. Bacterial burden is not strictly corre- lated with disease progression, and several hallmarks of severe tuberculosis suggest that insufficiently controlled inflammation plays an important role in pathogenesis.展开更多
Student contacts of tuberculosis（TB）cases are susceptible to latent tuberculosis infection（LTBI）,and chemo-prophylaxis can reduce the risk of active TB among them.This study aimed to assess the acceptance of chemo...Student contacts of tuberculosis（TB）cases are susceptible to latent tuberculosis infection（LTBI）,and chemo-prophylaxis can reduce the risk of active TB among them.This study aimed to assess the acceptance of chemo-prophylaxis for LTBI among students, and their concerns regarding TB and its preventive treatment.展开更多
Objective: to explore the effect of psychological nursing combined with health education on compliance of drug-resistant pulmonary tuberculosis patients. Methods: 100 cases of drug-resistant pulmonary tuberculosis pat...Objective: to explore the effect of psychological nursing combined with health education on compliance of drug-resistant pulmonary tuberculosis patients. Methods: 100 cases of drug-resistant pulmonary tuberculosis patients admitted in our hospital from October 2017 to December 2019 were randomly divided into observation group and control group with 50 cases in each group. The control group was given routine nursing combined with health education, while the observation group was given psychological nursing combined with health education. The two groups were compared in terms of compliance (medication rate according to the doctor's advice, treatment interruption rate, and regular examination), degree of knowledge mastery (adverse drug reactions, causes of disease, treatment principles, necessity of isolation) and nursing satisfaction. Results: after the intervention, the scores of medication rate, regular examination and adverse drug reactions, cause of disease, treatment principle and the necessity of isolation in the observation group were significantly higher than those in the control group (P < 0.05), while the interruption rate of treatment was significantly lower in the observation group (P < 0.05). The nursing satisfaction of the two groups of patients was higher than before the intervention, the observation group was significantly higher than the control group (P < 0.05). Conclusion: psychological nursing combined with health education for drug-resistant pulmonary tuberculosis can significantly reduce the interruption rate of treatment, and improve patients' compliance, knowledge mastery and nursing satisfaction.展开更多
Objective: to explore the relationship between medication compliance of pulmonary tuberculosis patients and nursing intervention. Methods: a total of 100 patients with pulmonary tuberculosis admitted to our hospital i...Objective: to explore the relationship between medication compliance of pulmonary tuberculosis patients and nursing intervention. Methods: a total of 100 patients with pulmonary tuberculosis admitted to our hospital in recent years were randomly divided into experimental group and observation group. The patients in the experimental group were treated with high-quality nursing intervention, while the patients in the observation group were only treated with conventional nursing methods. The effects of different nursing methods on their medication compliance were compared. Results: it was found that the experimental group adopted high-quality nursing, and the patients' medication compliance was significantly improved. There was a significant statistical difference between the two groups, which could be used as a comparison of experiments. Conclusion: the implementation of nursing intervention for pulmonary tuberculosis patients can improve the patients' medication compliance and promote their clinical use, which can effectively improve the patients' lives.展开更多
Objective: to study the effectiveness of "TRICE" in the treatment and prevention of tuberculosis under the condition of treating tuberculosis patients. Methods: from January 2012 to December 2020, 163 patien...Objective: to study the effectiveness of "TRICE" in the treatment and prevention of tuberculosis under the condition of treating tuberculosis patients. Methods: from January 2012 to December 2020, 163 patients with tuberculosis were randomly divided into two groups. The control group provided general medical treatment, while the research group introduced the model of tuberculosis compound. Self-care and quality of life before and after nursing were compared. Results: compared with the control group, the ability of self-care and quality of life in the study group was significantly different (P < 0.05). Conclusion: the introduction of "Triune" model of tuberculosis type of tuberculosis patients gives specific results, which increases the ability of patients to take care of patients independently and improve their quality of life.展开更多
Objective: to analyze the effect of personalized nursing in the process of disease understanding of pulmonary tuberculosis patients. Methods: 116 patients with pulmonary tuberculosis who were treated in our hospital f...Objective: to analyze the effect of personalized nursing in the process of disease understanding of pulmonary tuberculosis patients. Methods: 116 patients with pulmonary tuberculosis who were treated in our hospital from February 2019 to February in 2020 were selected as research subjects. The routine group and the study group were treated with ordinary nursing and personalized nursing. The awareness and nursing satisfaction of tuberculosis in two groups were compared. Results: the knowledge level of TB group was higher than that of the conventional group, and the results were statistically significant (P<0.05).The comparison shows that the satisfaction of the routine group is lower than that of the study group, and the comparison result is statistically significant (P < 0.05).Conclusion: the application of personalized nursing to the nursing process of pulmonary tuberculosis patients can make up for the loopholes in the original work, improve the nursing quality, increase the patients' awareness of their own diseases and improve the patients' compliance. Therefore, it can be popularized and applied in clinic.展开更多
Objective: to observe the effect of targeted nursing intervention on nutritional status and disease recovery of patients with pulmonary tuberculosis. Methods: 90 patients with pulmonary tuberculosis treated in our hos...Objective: to observe the effect of targeted nursing intervention on nutritional status and disease recovery of patients with pulmonary tuberculosis. Methods: 90 patients with pulmonary tuberculosis treated in our hospital from June 2018 to June 2020 were randomly divided into control group and targeted nursing group, with 45 cases in each group. The control group was given traditional routine nursing and the targeted nursing group was given targeted nursing. The changes of nutritional indexes, sputum negative conversion rate and cavity closure rate were compared between the two groups. Results: the levels of serum total protein (STP), serum albumin (ALB), RBC and Hb in the targeted nursing group were higher than those in the control group;The sputum negative conversion rate and cavity closure rate were 84.4% and 88.9% respectively, which were higher than 62.2% and 66.7% in the control group;The difference was statistically significant (P < 0.05). Conclusion: targeted nursing intervention can effectively improve the nutritional status, sputum negative conversion rate and cavity closure rate of pulmonary tuberculosis patients.展开更多
The objective of this prospective study of the risks of treatment failure in patients with drug-susceptible pulmonary tuberculosis （PTB） was to provide reference data to help develop a disease control strategy. Part...The objective of this prospective study of the risks of treatment failure in patients with drug-susceptible pulmonary tuberculosis （PTB） was to provide reference data to help develop a disease control strategy. Participants were recruited in eight provinces of China from October 2008 to December 2010. A total of 1447 patients with drug-susceptible PTB and older than 15 years of age were enrolled.展开更多
Objective To discuss perioperative features,operative approach and surgical effects of spinal tuberculosis in older patients.Methods Retrospective analysis was conducted to analyze the clinical data of 45 patients wit...Objective To discuss perioperative features,operative approach and surgical effects of spinal tuberculosis in older patients.Methods Retrospective analysis was conducted to analyze the clinical data of 45 patients with spinal展开更多
Introduction: In India, tuberculosis continues to be a major public health problem and there is a growing concern about drug-resistant tuberculosis as most of the patients are from private sector. The National TB Elim...Introduction: In India, tuberculosis continues to be a major public health problem and there is a growing concern about drug-resistant tuberculosis as most of the patients are from private sector. The National TB Elimination Programme (NTEP) in collaboration with TB Alert, India (TBAI) and Clinton Health Association of India (CHAI) had implemented a collaborative project to strengthen the network between the private practitioners and public healthcare facilities in New Delhi during 2019 and 2020. Methods: A study was conducted to understand the enablers and challenges encountered by them during the implementation of the project. This is a qualitative exploration of the “healthcare providers” on a project linking DR-TB patients in private sector with government health facilities. The process of data collection involved face-to-face in-depth interviews of healthcare providers, the Doctors mainly from private and public health facilities, the paramedical workers from general health system and paramedical from the project using an interview guide administered through a trained researcher. Results: The study findings revealed that all healthcare providers were completely aware of the DOST project in the health system, the model led to early diagnosis and initiation of quality treatment. There were no major challenges to the implementation of the project. The healthcare providers wish to have this project implemented for a longer duration. Conclusion: The perspectives of healthcare providers towards the “DOST” project were optimistic and call for re-initiating the project in the area.展开更多
Dear Editor,Infections are a common cause of stroke,and tuberculosis is one of the most dangerous causes of central nervous system（CNS）diseases.For example,cerebral infarction is a relatively common and serious CNS ...Dear Editor,Infections are a common cause of stroke,and tuberculosis is one of the most dangerous causes of central nervous system（CNS）diseases.For example,cerebral infarction is a relatively common and serious CNS disease associated with tuberculosis.展开更多
By means of polymerase chain reaction(PCR) technique,direct smear fluorescence microscopy and bacterial culture,the sputa and purulent secretion of 122 TB patients were examined to detect mycobacterium tuberculosis.
Background:South Africa has one of the world’s worst tuberculosis(TB)(520 per 100000 population)and TB-human immunodefciency virus(HIV)epidemics(~56%TB/HIV co-infected).While individual-and system-level factors infue...Background:South Africa has one of the world’s worst tuberculosis(TB)(520 per 100000 population)and TB-human immunodefciency virus(HIV)epidemics(~56%TB/HIV co-infected).While individual-and system-level factors infuencing progression along the TB cascade have been identifed,the impact of stigma is underexplored and underappreciated.We conducted an exploratory study to 1)describe diferences in perceived community-level TB stigma among community members,TB presumptives,and TB patients,and 2)identify factors associated with TB stigma levels among these groups.Methods:A cross sectional study was conducted in November 2017 at public health care facilities in Bufalo City Metro(BCM)and Zululand health districts,South Africa.Community members,TB presumptives,and TB patients were recruited.Data were collected on sociodemographic characteristics,TB knowledge,health and clinical history,social support,and both HIV and TB stigma.A validated scale assessing perceived community TB stigma was used.Univariate and multivariate linear regression models were used to describe diferences in perceived community TB stigma by participant type and to identify factors associated with TB stigma.Results:We enrolled 397 participants.On a scale of zero to 24,the mean stigma score for TB presumptives(14.7±4.4)was statistically higher than community members(13.6±4.8)and TB patients(13.3±5.1).Community members from Zululand(β=5.73;95%CI 2.19,9.72)had higher TB stigma compared to those from BCM.Previously having TB(β=−2.19;95%CI−4.37,0.0064)was associated with reduced TB stigma among community members.Understanding the relationship between HIV and TB disease(β=2.48;95%CI 0.020,4.94),and having low social support(β=−0.077;95%CI−0.14,0.010)were associated with increased TB stigma among TB presumptives.Among TB Patients,identifying as Black African(β=−2.90;95%CI−4.74,−1.04)and knowing the correct causes of TB(β=−2.93;95%CI−4.92,−0.94)were associated with decreased TB stigma,while understanding the relationship between HIV and TB disease(β=2.48;95%CI 1.05,3.90)and higher HIV stigma(β=0.32;95%CI 0.21,0.42)were associated with increased TB stigma.Conclusions:TB stigma interventions should be developed for TB presumptives,as stigma may increase initial-lossto-follow up.Given that stigma may be driven by numerous factors throughout the TB cascade,adaptive stigma reduction interventions may be required.展开更多
文摘Dear Editor： The emergence of multidrug-resistant tuberculosis （MDR-TB） is bringing new challenges. MDR-TB is caused by Mycobacterium tuberculosis （M. tuberculosis） that is resistant to isoniazid and rifampicin, with or with- out resistance to other anti-tuberculosis drugs. Approximately 450,000 people developed MDR-TB worldwide in 2012 and an estimated 170,000 people died from the disease. Bacterial burden is not strictly corre- lated with disease progression, and several hallmarks of severe tuberculosis suggest that insufficiently controlled inflammation plays an important role in pathogenesis.
基金supported by the National Key Science&Technology project against major infectious diseases[No.2017ZX10105012]the Fourth Round of Three-Year Public Health Action Plan of Shanghai,China[No.15GWZK0101]
文摘Student contacts of tuberculosis（TB）cases are susceptible to latent tuberculosis infection（LTBI）,and chemo-prophylaxis can reduce the risk of active TB among them.This study aimed to assess the acceptance of chemo-prophylaxis for LTBI among students, and their concerns regarding TB and its preventive treatment.
文摘Objective: to explore the effect of psychological nursing combined with health education on compliance of drug-resistant pulmonary tuberculosis patients. Methods: 100 cases of drug-resistant pulmonary tuberculosis patients admitted in our hospital from October 2017 to December 2019 were randomly divided into observation group and control group with 50 cases in each group. The control group was given routine nursing combined with health education, while the observation group was given psychological nursing combined with health education. The two groups were compared in terms of compliance (medication rate according to the doctor's advice, treatment interruption rate, and regular examination), degree of knowledge mastery (adverse drug reactions, causes of disease, treatment principles, necessity of isolation) and nursing satisfaction. Results: after the intervention, the scores of medication rate, regular examination and adverse drug reactions, cause of disease, treatment principle and the necessity of isolation in the observation group were significantly higher than those in the control group (P < 0.05), while the interruption rate of treatment was significantly lower in the observation group (P < 0.05). The nursing satisfaction of the two groups of patients was higher than before the intervention, the observation group was significantly higher than the control group (P < 0.05). Conclusion: psychological nursing combined with health education for drug-resistant pulmonary tuberculosis can significantly reduce the interruption rate of treatment, and improve patients' compliance, knowledge mastery and nursing satisfaction.
文摘Objective: to explore the relationship between medication compliance of pulmonary tuberculosis patients and nursing intervention. Methods: a total of 100 patients with pulmonary tuberculosis admitted to our hospital in recent years were randomly divided into experimental group and observation group. The patients in the experimental group were treated with high-quality nursing intervention, while the patients in the observation group were only treated with conventional nursing methods. The effects of different nursing methods on their medication compliance were compared. Results: it was found that the experimental group adopted high-quality nursing, and the patients' medication compliance was significantly improved. There was a significant statistical difference between the two groups, which could be used as a comparison of experiments. Conclusion: the implementation of nursing intervention for pulmonary tuberculosis patients can improve the patients' medication compliance and promote their clinical use, which can effectively improve the patients' lives.
文摘Objective: to study the effectiveness of "TRICE" in the treatment and prevention of tuberculosis under the condition of treating tuberculosis patients. Methods: from January 2012 to December 2020, 163 patients with tuberculosis were randomly divided into two groups. The control group provided general medical treatment, while the research group introduced the model of tuberculosis compound. Self-care and quality of life before and after nursing were compared. Results: compared with the control group, the ability of self-care and quality of life in the study group was significantly different (P < 0.05). Conclusion: the introduction of "Triune" model of tuberculosis type of tuberculosis patients gives specific results, which increases the ability of patients to take care of patients independently and improve their quality of life.
文摘Objective: to analyze the effect of personalized nursing in the process of disease understanding of pulmonary tuberculosis patients. Methods: 116 patients with pulmonary tuberculosis who were treated in our hospital from February 2019 to February in 2020 were selected as research subjects. The routine group and the study group were treated with ordinary nursing and personalized nursing. The awareness and nursing satisfaction of tuberculosis in two groups were compared. Results: the knowledge level of TB group was higher than that of the conventional group, and the results were statistically significant (P<0.05).The comparison shows that the satisfaction of the routine group is lower than that of the study group, and the comparison result is statistically significant (P < 0.05).Conclusion: the application of personalized nursing to the nursing process of pulmonary tuberculosis patients can make up for the loopholes in the original work, improve the nursing quality, increase the patients' awareness of their own diseases and improve the patients' compliance. Therefore, it can be popularized and applied in clinic.
文摘Objective: to observe the effect of targeted nursing intervention on nutritional status and disease recovery of patients with pulmonary tuberculosis. Methods: 90 patients with pulmonary tuberculosis treated in our hospital from June 2018 to June 2020 were randomly divided into control group and targeted nursing group, with 45 cases in each group. The control group was given traditional routine nursing and the targeted nursing group was given targeted nursing. The changes of nutritional indexes, sputum negative conversion rate and cavity closure rate were compared between the two groups. Results: the levels of serum total protein (STP), serum albumin (ALB), RBC and Hb in the targeted nursing group were higher than those in the control group;The sputum negative conversion rate and cavity closure rate were 84.4% and 88.9% respectively, which were higher than 62.2% and 66.7% in the control group;The difference was statistically significant (P < 0.05). Conclusion: targeted nursing intervention can effectively improve the nutritional status, sputum negative conversion rate and cavity closure rate of pulmonary tuberculosis patients.
基金supported by the National Science and Technology Major Project of China(2008ZX10003-008-02)
文摘The objective of this prospective study of the risks of treatment failure in patients with drug-susceptible pulmonary tuberculosis （PTB） was to provide reference data to help develop a disease control strategy. Participants were recruited in eight provinces of China from October 2008 to December 2010. A total of 1447 patients with drug-susceptible PTB and older than 15 years of age were enrolled.
文摘Objective To discuss perioperative features,operative approach and surgical effects of spinal tuberculosis in older patients.Methods Retrospective analysis was conducted to analyze the clinical data of 45 patients with spinal
文摘Introduction: In India, tuberculosis continues to be a major public health problem and there is a growing concern about drug-resistant tuberculosis as most of the patients are from private sector. The National TB Elimination Programme (NTEP) in collaboration with TB Alert, India (TBAI) and Clinton Health Association of India (CHAI) had implemented a collaborative project to strengthen the network between the private practitioners and public healthcare facilities in New Delhi during 2019 and 2020. Methods: A study was conducted to understand the enablers and challenges encountered by them during the implementation of the project. This is a qualitative exploration of the “healthcare providers” on a project linking DR-TB patients in private sector with government health facilities. The process of data collection involved face-to-face in-depth interviews of healthcare providers, the Doctors mainly from private and public health facilities, the paramedical workers from general health system and paramedical from the project using an interview guide administered through a trained researcher. Results: The study findings revealed that all healthcare providers were completely aware of the DOST project in the health system, the model led to early diagnosis and initiation of quality treatment. There were no major challenges to the implementation of the project. The healthcare providers wish to have this project implemented for a longer duration. Conclusion: The perspectives of healthcare providers towards the “DOST” project were optimistic and call for re-initiating the project in the area.
文摘Dear Editor,Infections are a common cause of stroke,and tuberculosis is one of the most dangerous causes of central nervous system（CNS）diseases.For example,cerebral infarction is a relatively common and serious CNS disease associated with tuberculosis.
文摘By means of polymerase chain reaction(PCR) technique,direct smear fluorescence microscopy and bacterial culture,the sputa and purulent secretion of 122 TB patients were examined to detect mycobacterium tuberculosis.
文摘Background:South Africa has one of the world’s worst tuberculosis(TB)(520 per 100000 population)and TB-human immunodefciency virus(HIV)epidemics(~56%TB/HIV co-infected).While individual-and system-level factors infuencing progression along the TB cascade have been identifed,the impact of stigma is underexplored and underappreciated.We conducted an exploratory study to 1)describe diferences in perceived community-level TB stigma among community members,TB presumptives,and TB patients,and 2)identify factors associated with TB stigma levels among these groups.Methods:A cross sectional study was conducted in November 2017 at public health care facilities in Bufalo City Metro(BCM)and Zululand health districts,South Africa.Community members,TB presumptives,and TB patients were recruited.Data were collected on sociodemographic characteristics,TB knowledge,health and clinical history,social support,and both HIV and TB stigma.A validated scale assessing perceived community TB stigma was used.Univariate and multivariate linear regression models were used to describe diferences in perceived community TB stigma by participant type and to identify factors associated with TB stigma.Results:We enrolled 397 participants.On a scale of zero to 24,the mean stigma score for TB presumptives(14.7±4.4)was statistically higher than community members(13.6±4.8)and TB patients(13.3±5.1).Community members from Zululand(β=5.73;95%CI 2.19,9.72)had higher TB stigma compared to those from BCM.Previously having TB(β=−2.19;95%CI−4.37,0.0064)was associated with reduced TB stigma among community members.Understanding the relationship between HIV and TB disease(β=2.48;95%CI 0.020,4.94),and having low social support(β=−0.077;95%CI−0.14,0.010)were associated with increased TB stigma among TB presumptives.Among TB Patients,identifying as Black African(β=−2.90;95%CI−4.74,−1.04)and knowing the correct causes of TB(β=−2.93;95%CI−4.92,−0.94)were associated with decreased TB stigma,while understanding the relationship between HIV and TB disease(β=2.48;95%CI 1.05,3.90)and higher HIV stigma(β=0.32;95%CI 0.21,0.42)were associated with increased TB stigma.Conclusions:TB stigma interventions should be developed for TB presumptives,as stigma may increase initial-lossto-follow up.Given that stigma may be driven by numerous factors throughout the TB cascade,adaptive stigma reduction interventions may be required.
