The work takes a new liquid-cooling plate in a power battery with pin fins inside the channel as the object.A mathematical model is established via the central composite design of the response surface to study the rel...The work takes a new liquid-cooling plate in a power battery with pin fins inside the channel as the object.A mathematical model is established via the central composite design of the response surface to study the relationships among the length,width,height,and spacing of pin fins;the maximum temperature and temperature difference of the battery module;and the pressure drop of the liquid-cooling plate.Model accuracy is verified via variance analysis.The new liquid-cooling plate enables the power battery to work within an optimal temperature range.Appropriately increasing the length,width,and height and reducing the spacing of pin fins could reduce the temperature of the power battery module and improve the temperature uniformity.However,the pressure drop of the liquid-cooling plate increases.The structural parameters of the pin fins are optimized to minimize the maximum temperature and the temperature difference of the battery module as well as the pressure drop of the liquid-cooling plate.The errors between the values predicted and actual by the simulation test are 0.58%,4%,and 0.48%,respectively,which further verifies the model accuracy.The results reveal the influence of the structural parameters of the pin fins inside the liquid-cooling plate on its heat dissipation performance and pressure drop characteristics.A theoretical basis is provided for the design of liquid-cooling plates in power batteries and the optimization of structural parameters.展开更多
Device robust-design is inherently a multiple-objective optimization problem.Using design of experiments (DoE) combined with response surface methodology (RSM) can satisfy the great incentive to reduce the number of t...Device robust-design is inherently a multiple-objective optimization problem.Using design of experiments (DoE) combined with response surface methodology (RSM) can satisfy the great incentive to reduce the number of technology CAD(TCAD) simulations that need to be performed.However,the errors of RSM models might be large enough to diminish the validity of the results for some nonlinear problems.To find the feasible design space,a new method with objectives-oriented design in generations that takes the errors of RSM model into account is presented.After the augment design of experiments in promising space according to the results of RSM model in current generation,the feasible space will be emerging as the model errors deceasing.The results on FIBMOS examples show that the methodology is efficient.展开更多
Statistical experimental designs were used to optimize the process of phenol degradation by Candida tropicalis Z-04, isolated from phenol-degrading aerobic granules. The most important factors influencing phenol degra...Statistical experimental designs were used to optimize the process of phenol degradation by Candida tropicalis Z-04, isolated from phenol-degrading aerobic granules. The most important factors influencing phenol degradation （p 〈 0.05）, as identified by a two-level Plackett-Burman design with 11 variables, were yeast extract, phenol, inoculum size, and temperature. Steepest ascent method was undertaken to determine the optimal regions of these four significant factors. Central composite design （CCD） and response surface analysis were adopted to further investigate the mutual interactions between these variables and to identify their optimal values that would generate maximum phenol degradation. The analysis results indicated that interactions between yeast extract and temperature, phenol and temperature, inocuhim size and temperature affected the response variable （phenol degradation） significantly. The predicted results showed that the maximum removal efficiency of phenol （99.10%） could be obtained under the optimum conditions of yeast extract 0.41 g/L, phenol 1.03 g/L, inoculum size 1.43% （V/V） and temperature 30.04℃. These predicted values were further verified by validation experiments. The excellent correlation between predicted and experimental values confirmed the validity and practicability of this statistical optimum strategy. This study indicated the excellent ability of C. tropicalis Z-04 in degrading high-strength phenol. Optimal conditions obtained in this experiment laid a solid foundation for further use of this microorganism in the treatment of highstrength phenol effluents.展开更多
Turbine blade is one of the critical components of aircraft engine.The performance of the engine depends on the shape and dimensions of components,but superalloy blade material cannot be easily machined.Although inves...Turbine blade is one of the critical components of aircraft engine.The performance of the engine depends on the shape and dimensions of components,but superalloy blade material cannot be easily machined.Although investment casting is an ideal process for such net-shape components,it requires an accurate determination of the casting-die profile.In this paper,a reversing design methodology for investment casting die using ProCAST is proposed.By combining the methods of simplifying grid files and quick sorting,the efficiency of sorting and matching can be largely improved.Further,the mould/die cavity anti-deformation system can be easily built.With ProCAST,the optimized die profile for investment casting can be established.展开更多
The aim of this paper is to investigate and optimize the preparation of scutellarin(SCU)-loaded HP-β-CD/chitosan(CS) nanoparticles(CD/CS-SCU-NPs). CD/CS-SCU-NPs were prepared by ionic cross-linking method and the pro...The aim of this paper is to investigate and optimize the preparation of scutellarin(SCU)-loaded HP-β-CD/chitosan(CS) nanoparticles(CD/CS-SCU-NPs). CD/CS-SCU-NPs were prepared by ionic cross-linking method and the process and formulation variables were optimized using response surface methodology(RSM) with a three-level, three factor Box–Behnken design(BBD).The independent variables were the added amounts of CS, sodium tripolyphosphate(TPP)and Pluronic F-68 during the preparation. Dependent variables(responses) were particle size and entrapment efficiency. Mathematical equations and respond surface plots were used to correlate independent and dependent variables.The preparation process and formulation variables were optimized to achieve minimum particle size and maximum entrapment efficiency by calculating the overall desirability value(OD). The optimized NP formulation was characterized for particle size, PDI, zeta potential, entrapment efficiency and in vitro drug release.According to the results, an optimized CD/CS-SCU-NP formulation was prepared. Results for particle size, PDI, zeta potential and entrapment efficiency were found to be around 200 nm,0.5, 25 mV, and 70% respectively. For in vitro study, the release of SCU from the NPs exhibited a biphasic release and was in accordance with Higuchi equation. The optimized preparation was simple with the probability for industrialization. The combination use of RSM, BBD and overall desirability values could provide a promising application for incorporating CD into CS nanoparticles as drug delivery carrier and help develop lab-scale procedures.展开更多
A new method for optimizing a butterfly-shaped linear ultrasonic motor was proposed to maximize its mechanical output. The finite element analysis technology and response surface methodology were combined together to ...A new method for optimizing a butterfly-shaped linear ultrasonic motor was proposed to maximize its mechanical output. The finite element analysis technology and response surface methodology were combined together to realize the optimal design of the butterfly-shaped linear ultrasonic motor. First, the operation principle of the motor was introduced. Second, the finite element parameterized model of the stator of the motor was built using ANSYS parametric design language and some structure parameters of the stator were selected as design variables. Third, the sample points were selected in design variable space using latin hypercube Design. Through modal analysis and harmonic response analysis of the stator based on these sample points, the target responses were obtained. These sample points and response values were combined together to build a response surface model. Finally, the simplex method was used to find the optimal solution. The experimental results showed that many aspects of the design requirements of the butterfly-shaped linear ultrasonic motor have been fulfilled. The prototype motor fabricated based on the optimal design result exhibited considerably high dynamic performance, such as no-load speed of 873 ram/s, maximal thrust of 27.5 N, maximal efficiency of 43%, and thrust-weight ratio of 45.8.展开更多
This study discussed the application of response surface methodology(RSM)and central composite rotatable design(CCRD)for modeling and optimization of the influence of some operating variables on the performance of a l...This study discussed the application of response surface methodology(RSM)and central composite rotatable design(CCRD)for modeling and optimization of the influence of some operating variables on the performance of a lab scale thickener for dewatering of tailing in the flotation circuit.Four thickener operating variables,namely feed flowrate,solid percent,flocculant dosage and feedwell height were changed during the tests based on CCRD.The ranges of values of the thickener variables used in the design were a feed flowrate of 9–21 L/min,solid percent of 8%–20%,flocculant dosage of 1.25–4.25 g/t and feedwell height of 16–26 cm.A total of 30 thickening tests were conducted using lab scale thickener on flotation tailing obtained from the Sarcheshmeh copper mine,Iran.The underflow solid percent and bed height were expressed as functions of four operating parameters of thickener.Predicted values were found to be in good agreement with experimental values(R2values of 0.992 and 0.997 for underflow solid percent and bed height,respectively).This study has shown that the RSM and CCRD could effciently be applied for the modeling of thickener for dewatering of flotation tailing.展开更多
In this paper,a methodology for designing mooring system deployment for vessels at varying water depths is proposed.The Non-dominated Sorting Genetic Algorithm-II(NSGA-II)is combined with a self-dependently developed ...In this paper,a methodology for designing mooring system deployment for vessels at varying water depths is proposed.The Non-dominated Sorting Genetic Algorithm-II(NSGA-II)is combined with a self-dependently developed vessel-mooring coupled program to find the optimal mooring system deployment considering both station-keeping requirements and the safety of the mooring system.Two case studies are presented to demonstrate the methodology by designing the mooring system deployments for a very large floating structure(VLFS)module and a semi-submersible platform respectively at three different water depths.It can be concluded from the obtained results that the mooring system can achieve a better station-keeping ability with relatively shorter mooring line when deployed in the shallow water.The safety factor of mooring line is mainly dominated by the maximum instantaneous tension increment in the shallow water,while the pre-tension has a decisive influence on the safety factor of the mooring line in the deep water.展开更多
This paper presents an innovative Soft Design Science Methodology for improving information systems security using multi-layered security approach. The study applied Soft Design Science Methodology to address the prob...This paper presents an innovative Soft Design Science Methodology for improving information systems security using multi-layered security approach. The study applied Soft Design Science Methodology to address the problematic situation on how information systems security can be improved. In addition, Soft Design Science Methodology was compounded with mixed research methodology. This holistic approach helped for research methodology triangulation. The study assessed security requirements and developed a framework for improving information systems security. The study carried out maturity level assessment to determine security status quo in the education sector in Tanzania. The study identified security requirements gap (IT security controls, IT security measures) using ISO/IEC 21827: Systems Security Engineering-Capability Maturity Model (SSE-CMM) with a rating scale of 0 - 5. The results of this study show that maturity level across security domain is 0.44 out of 5. The finding shows that the implementation of IT security controls and security measures for ensuring security goals are lacking or conducted in ad-hoc. Thus, for improving the security of information systems, organisations should implement security controls and security measures in each security domain (multi-layer security). This research provides a framework for enhancing information systems security during capturing, processing, storage and transmission of information. This research has several practical contributions. Firstly, it contributes to the body of knowledge of information systems security by providing a set of security requirements for ensuring information systems security. Secondly, it contributes empirical evidence on how information systems security can be improved. Thirdly, it contributes on the applicability of Soft Design Science Methodology on addressing the problematic situation in information systems security. The research findings can be used by decision makers and lawmakers to improve existing cyber security laws, and enact laws for data privacy and sharing of open data.展开更多
Minimizing the impact of the mixed uncertainties(i.e.,the aleatory uncertainty and the epistemic uncertainty) for a complex product of compliant mechanism(CPCM) quality improvement signifies a fascinating research top...Minimizing the impact of the mixed uncertainties(i.e.,the aleatory uncertainty and the epistemic uncertainty) for a complex product of compliant mechanism(CPCM) quality improvement signifies a fascinating research topic to enhance the robustness.However, most of the existing works in the CPCM robust design optimization neglect the mixed uncertainties, which might result in an unstable design or even an infeasible design. To solve this issue, a response surface methodology-based hybrid robust design optimization(RSM-based HRDO) approach is proposed to improve the robustness of the quality characteristic for the CPCM via considering the mixed uncertainties in the robust design optimization. A bridge-type amplification mechanism is used to manifest the effectiveness of the proposed approach. The comparison results prove that the proposed approach can not only keep its superiority in the robustness, but also provide a robust scheme for optimizing the design parameters.展开更多
In this study,the enhancement of catalytic activity of ceria when modified with co-catalysts such as graphitic carbon nitride and silver was establishe d.The material was synthe sized using phytogenic combustion metho...In this study,the enhancement of catalytic activity of ceria when modified with co-catalysts such as graphitic carbon nitride and silver was establishe d.The material was synthe sized using phytogenic combustion method,a green alternative to the traditional preparative routes.The catalyst was characterized using XRD,FTIR,SEM,EDX,XPS and TEM techniques.The synergistic effect of the composite CeO2/g-C3 N4/Ag was tested for catalytic reduction of 4-nitrophenol in the prese nce of sodium borohydride.The reaction was carried out at room tempe rature without any light source or exte rnal stirring.The individual and combined effects of four parameters,viz.,concentration of 4-NP,amount of catalyst,amount of NaBH4 and time for the reduction of reduction 4-NP were investigated using Box-Behnken design of response surface methodology(RSM).This statistical model was used to optimize the reaction conditions for maximum reduction of 4-NP.The optimum conditions for the reduction reaction are found to be 0.01 mmol/L 4-NP,15 mg catalyst,20 mg NaBH4 and 13.7 min time interval.展开更多
Aircraft collaboration design is based on a unified set of schemas containing data and model representations and interfaces across disciplines.The aircraft design schema is a central data model that specifies the para...Aircraft collaboration design is based on a unified set of schemas containing data and model representations and interfaces across disciplines.The aircraft design schema is a central data model that specifies the paradigm for the representation of a full lifecycle model of aircraft design.The construction of the schema currently lacks theoretical guidance.This paper designs a novel methodology to construct the aircraft design schema,a fully functional,logical,and selfconsistent methodology.The methodology defines a schema matrix that includes implementation strategies,principles,processes,meta-object facility,views,scenarios,and products.The aircraft conceptual design schema is constructed according to the methodology,which is a hands-on approach to help understand the concept and implementation.The features of the methodology are analyzed,and the methodology and the aircraft conceptual design schema are presented to address the pain points of multiple solution trade-offs,multiple iterations,and multidisciplinary coupling in aircraft conceptual collaboration design.展开更多
As a kind of natural fiber,ramie fiber has distinctive advantages in textile application,but the application is limited due to the traditional degumming mode.Compared with the traditional degumming process,the microbi...As a kind of natural fiber,ramie fiber has distinctive advantages in textile application,but the application is limited due to the traditional degumming mode.Compared with the traditional degumming process,the microbial degumming process has many advantages.To obtain the optimal conditions for degumming ramie with Bacillus subtilis DZ_(5)(BS DZ_(5)),a combined statistical approach of orthogonal array design(OAD)and response surface methodology(RSM)was used.The influences of initial pH of the bacteria medium,culture temperature,shaking speed,degumming time and inoculum size on submerged fermentation degumming were evaluated by using fractional factorial design.The main factors in the analysis were culture temperature,shaking speed and initial pH.The residual gum mass fraction was used as the optimization index,and the optimal conditions for degumming were determined by central composite design and RSM.Thus with only a limited number of experiments,an optimal ramie microbial degumming condition was found as the culture temperature of 40℃,the initial pH in the culture medium of 8.5,the shaking speed of 205 r/min,the degumming time of 96 h and the inoculum size of 5%.After microbial degumming of ramie under the optimal conditions,there was only 10.6%residual gum by mass in the fiber.In addition,the effective degumming of BS DZ_(5)was also confirmed by a scanning electron microscope(SEM).展开更多
An intelligent response surface methodology (IRSM) was proposed to achieve the most competitive metal forming products, in which artificial intelligence technologies are introduced into the optimization process. It is...An intelligent response surface methodology (IRSM) was proposed to achieve the most competitive metal forming products, in which artificial intelligence technologies are introduced into the optimization process. It is used as simple and inexpensive replacement for computationally expensive simulation model. In IRSM, the optimal design space can be reduced greatly without any prior information about function distribution. Also, by identifying the approximation error region, new design points can be supplemented correspondingly to improve the response surface model effectively. The procedure is iterated until the accuracy reaches the desired threshold value. Thus, the global optimization can be performed based on this substitute model. Finally, we present an optimization design example about roll forming of a "U" channel product.展开更多
<span style="font-family:Verdana;">The Building Information Modeling (BIM) methodology considers the representation of the building as a virtual BIM model and its main concept is to centralize all the ...<span style="font-family:Verdana;">The Building Information Modeling (BIM) methodology considers the representation of the building as a virtual BIM model and its main concept is to centralize all the information generated throughout the development of the project. Structural design involves a set of tasks, namely, structure definition, structural analyses, and after the generation of drawings and technical documentation. In all processes, it is required confidence in data transferred between the BIM systems used, and to support this, a high level of interoperability is claimed. The present study aims to evaluate the degree of interoperability between the BIM-based platforms, ArchiCAD (Graphisoft), Revit (Autodesk), and ETABS (CSI). Two-way data flows between these systems were explored using distinct transfer strategies: add-in applications;Industry Foundation Classes (IFC) standard data format. The research made allows identifying the most appropriate procedure to be adopted by structural engineers, given the interoperability limitations verified, enabling the establishment of a practical guide of sequential procedures on the development of structural designs using BIM tools.</span>展开更多
Isoamylene from the Fischer-Tropsch syncrude can be transformed to valuable fuel oxygenate additives through an equilibrium limited etherification reaction with methanol. A reactive distillation process is established...Isoamylene from the Fischer-Tropsch syncrude can be transformed to valuable fuel oxygenate additives through an equilibrium limited etherification reaction with methanol. A reactive distillation process is established to increase isoamylene conversion. Facing the challenge of improving product purity at the same time, an equilibrium stage model based design methodology is proposed and illustrated step-by-step for converting the Fischer-Tropsch C_5 olefins to tert-amyl methyl ether(TAME) process by using Aspen Plus. Under the guide of the proposed methodology, the design leads to a TAME product purity of higher than 95% and an isoamylene conversion of higher than 90%. The etherification kinetics over Amberlyst 35 is also studied within a temperature range of 60 ℃ to 75 ℃ to shed more light on the feasibility of process development. The methodology provides an effective reactive distillation column design to achieve the target reactant conversion and product purity simultaneously.展开更多
Aiming at the problems cased by the fast increase of industry and popula-tion in China,the paper cxpounds the conceptual connotation of urban dcsign and theinteraction between urban form and design,sums up the“top-d...Aiming at the problems cased by the fast increase of industry and popula-tion in China,the paper cxpounds the conceptual connotation of urban dcsign and theinteraction between urban form and design,sums up the“top-down”and“bottom-up”urban design approaches in history,and points out that subject of urban design——as anavailable approach to cope with the problems of building cities——should be put forwardin China as quickly as possible.展开更多
This study employed the Box-Behnken design in response surface methodology(RSM)to optimize predistillation and pressurized distillation column parameters in methanol distillation.Statistical and fittinganalyses demons...This study employed the Box-Behnken design in response surface methodology(RSM)to optimize predistillation and pressurized distillation column parameters in methanol distillation.Statistical and fittinganalyses demonstrated the effects of operational parameters and their interactions on product purity and operating costs.Results showed that for methanol mass fraction in the product,the top distillate of the predistillation column(D_(1)),the interaction between D_(1) and the top distillate of the pressurized distillation column(D_(2)),and the interaction between the theoretical plates of the pressurized distillation column(N_(2))and its refluxratio(R_(2))significantlyaffected the outcome,in addition to pressurized distillation column parameters.Acetone mass fraction was mainly influencedby predistillation column parameters and their interactions,with minimal relation to the pressurized distillation column.Operating costs were primarily affected by the refluxratio(R),withdrawal(D)of both columns,and their interactions.Optimization strategies involved increasing theoretical plates and reducing refluxratios compared to the initial plan,achieving energy-saving and consumption-reduction goals.The process required the pressurized distillation column‘s methanol mass fraction to exceed 99.80%,acetone mass fraction below 2×10^(-8),and formaldehyde mass fraction below 5×10^(-9),with a feed rate of 6100 kg·h^(-1).Plans A,B,and C achieved energy-savings of 29.80%,21.78%,and 25.50%respectively,while ensuring separation efficiencyand product quality.This research provides theoretical and practical guidance for optimizing the methanol distillation process,helping to reduce energy consumption and production costs,thereby enhancing corporate competitiveness.展开更多
Probes are the interface between microsystems and bio-cells.The ideal interface is one-to-one interface.Though various research groups have been able to establish some sort of interfaces after many years of research,t...Probes are the interface between microsystems and bio-cells.The ideal interface is one-to-one interface.Though various research groups have been able to establish some sort of interfaces after many years of research,they are very crude.Neurons are millions in numbers,whereas the prostheses successfully built so far have only a few hundred probes at best.Creating an ef- fective interface is still far away.Though we have micro-and nano-technologies,we couldn't build a prosthesis with an effective resolution.Main reasons behind it are the type of probe being used and the poor design of the probe.To address this problem,we developed a methodology to design a probe and an array of probes with better resolution and less resistive donut probe.This methodology helps us to design a probe optimizing all the parameters.We presented our methodology through a design that is capable of 70 μm penetration inside the tissue.The tissue heating by our designed probe is only 0.411 °C.We also characterized the donut probe,which could be used by any research group to design a donut probe of their specific need.展开更多
[Objectives] The research aimed to optimize extraction process of Clerodendrum philippinum Schauer var. simplex Mlodenke total flavonoids( CPTF),and provide reference for its development and utilization. [Methods] Bas...[Objectives] The research aimed to optimize extraction process of Clerodendrum philippinum Schauer var. simplex Mlodenke total flavonoids( CPTF),and provide reference for its development and utilization. [Methods] Based on single-factor test,ethanol concentration,extraction temperature and extraction time were taken as independent variables,and total flavonoids yield was taken as dependent variable. The test was conducted according to central composite design principle. Multivariate linear regression and binomial equation fitting of the result were conducted,and extraction process of CPTF was optimized by using response surface methodology. [Results]The optimal extraction process of CPTF was as below: ethanol concentration 54. 76%,extraction temperature 83. 92℃,extraction time 102. 64 min,solid-liquid ratio 1:20,extraction for twice. [Conclusions] The extraction process of CPTF by central composite design-response surface methodology was simple and feasible,with reliable prediction result,which was suitable for industrial production.展开更多
基金supported by the Education and Teaching Research Project of Universities in Fujian Province(FBJY20230167).
文摘The work takes a new liquid-cooling plate in a power battery with pin fins inside the channel as the object.A mathematical model is established via the central composite design of the response surface to study the relationships among the length,width,height,and spacing of pin fins;the maximum temperature and temperature difference of the battery module;and the pressure drop of the liquid-cooling plate.Model accuracy is verified via variance analysis.The new liquid-cooling plate enables the power battery to work within an optimal temperature range.Appropriately increasing the length,width,and height and reducing the spacing of pin fins could reduce the temperature of the power battery module and improve the temperature uniformity.However,the pressure drop of the liquid-cooling plate increases.The structural parameters of the pin fins are optimized to minimize the maximum temperature and the temperature difference of the battery module as well as the pressure drop of the liquid-cooling plate.The errors between the values predicted and actual by the simulation test are 0.58%,4%,and 0.48%,respectively,which further verifies the model accuracy.The results reveal the influence of the structural parameters of the pin fins inside the liquid-cooling plate on its heat dissipation performance and pressure drop characteristics.A theoretical basis is provided for the design of liquid-cooling plates in power batteries and the optimization of structural parameters.
文摘Device robust-design is inherently a multiple-objective optimization problem.Using design of experiments (DoE) combined with response surface methodology (RSM) can satisfy the great incentive to reduce the number of technology CAD(TCAD) simulations that need to be performed.However,the errors of RSM models might be large enough to diminish the validity of the results for some nonlinear problems.To find the feasible design space,a new method with objectives-oriented design in generations that takes the errors of RSM model into account is presented.After the augment design of experiments in promising space according to the results of RSM model in current generation,the feasible space will be emerging as the model errors deceasing.The results on FIBMOS examples show that the methodology is efficient.
基金supported by the National Natural Science Foundation of China (No.50778110)
文摘Statistical experimental designs were used to optimize the process of phenol degradation by Candida tropicalis Z-04, isolated from phenol-degrading aerobic granules. The most important factors influencing phenol degradation （p 〈 0.05）, as identified by a two-level Plackett-Burman design with 11 variables, were yeast extract, phenol, inoculum size, and temperature. Steepest ascent method was undertaken to determine the optimal regions of these four significant factors. Central composite design （CCD） and response surface analysis were adopted to further investigate the mutual interactions between these variables and to identify their optimal values that would generate maximum phenol degradation. The analysis results indicated that interactions between yeast extract and temperature, phenol and temperature, inocuhim size and temperature affected the response variable （phenol degradation） significantly. The predicted results showed that the maximum removal efficiency of phenol （99.10%） could be obtained under the optimum conditions of yeast extract 0.41 g/L, phenol 1.03 g/L, inoculum size 1.43% （V/V） and temperature 30.04℃. These predicted values were further verified by validation experiments. The excellent correlation between predicted and experimental values confirmed the validity and practicability of this statistical optimum strategy. This study indicated the excellent ability of C. tropicalis Z-04 in degrading high-strength phenol. Optimal conditions obtained in this experiment laid a solid foundation for further use of this microorganism in the treatment of highstrength phenol effluents.
基金supported by National Key Technologies R&D Program under Grant No. 2006BAF04B02
文摘Turbine blade is one of the critical components of aircraft engine.The performance of the engine depends on the shape and dimensions of components,but superalloy blade material cannot be easily machined.Although investment casting is an ideal process for such net-shape components,it requires an accurate determination of the casting-die profile.In this paper,a reversing design methodology for investment casting die using ProCAST is proposed.By combining the methods of simplifying grid files and quick sorting,the efficiency of sorting and matching can be largely improved.Further,the mould/die cavity anti-deformation system can be easily built.With ProCAST,the optimized die profile for investment casting can be established.
基金supported by the Academic Research Fund,Faculty of Science,National University of Singapore,R148-000-180-112
文摘The aim of this paper is to investigate and optimize the preparation of scutellarin(SCU)-loaded HP-β-CD/chitosan(CS) nanoparticles(CD/CS-SCU-NPs). CD/CS-SCU-NPs were prepared by ionic cross-linking method and the process and formulation variables were optimized using response surface methodology(RSM) with a three-level, three factor Box–Behnken design(BBD).The independent variables were the added amounts of CS, sodium tripolyphosphate(TPP)and Pluronic F-68 during the preparation. Dependent variables(responses) were particle size and entrapment efficiency. Mathematical equations and respond surface plots were used to correlate independent and dependent variables.The preparation process and formulation variables were optimized to achieve minimum particle size and maximum entrapment efficiency by calculating the overall desirability value(OD). The optimized NP formulation was characterized for particle size, PDI, zeta potential, entrapment efficiency and in vitro drug release.According to the results, an optimized CD/CS-SCU-NP formulation was prepared. Results for particle size, PDI, zeta potential and entrapment efficiency were found to be around 200 nm,0.5, 25 mV, and 70% respectively. For in vitro study, the release of SCU from the NPs exhibited a biphasic release and was in accordance with Higuchi equation. The optimized preparation was simple with the probability for industrialization. The combination use of RSM, BBD and overall desirability values could provide a promising application for incorporating CD into CS nanoparticles as drug delivery carrier and help develop lab-scale procedures.
基金Projects(51275235, 50975135) supported by the National Natural Science Foundation of ChinaProject(U0934004) supported by the Natural Science Foundation of Guangdong Province, ChinaProject(2011CB707602) supported by the National Basic Research Program of China
文摘A new method for optimizing a butterfly-shaped linear ultrasonic motor was proposed to maximize its mechanical output. The finite element analysis technology and response surface methodology were combined together to realize the optimal design of the butterfly-shaped linear ultrasonic motor. First, the operation principle of the motor was introduced. Second, the finite element parameterized model of the stator of the motor was built using ANSYS parametric design language and some structure parameters of the stator were selected as design variables. Third, the sample points were selected in design variable space using latin hypercube Design. Through modal analysis and harmonic response analysis of the stator based on these sample points, the target responses were obtained. These sample points and response values were combined together to build a response surface model. Finally, the simplex method was used to find the optimal solution. The experimental results showed that many aspects of the design requirements of the butterfly-shaped linear ultrasonic motor have been fulfilled. The prototype motor fabricated based on the optimal design result exhibited considerably high dynamic performance, such as no-load speed of 873 ram/s, maximal thrust of 27.5 N, maximal efficiency of 43%, and thrust-weight ratio of 45.8.
基金supported by the National Iranian Copper Industry Co.
文摘This study discussed the application of response surface methodology(RSM)and central composite rotatable design(CCRD)for modeling and optimization of the influence of some operating variables on the performance of a lab scale thickener for dewatering of tailing in the flotation circuit.Four thickener operating variables,namely feed flowrate,solid percent,flocculant dosage and feedwell height were changed during the tests based on CCRD.The ranges of values of the thickener variables used in the design were a feed flowrate of 9–21 L/min,solid percent of 8%–20%,flocculant dosage of 1.25–4.25 g/t and feedwell height of 16–26 cm.A total of 30 thickening tests were conducted using lab scale thickener on flotation tailing obtained from the Sarcheshmeh copper mine,Iran.The underflow solid percent and bed height were expressed as functions of four operating parameters of thickener.Predicted values were found to be in good agreement with experimental values(R2values of 0.992 and 0.997 for underflow solid percent and bed height,respectively).This study has shown that the RSM and CCRD could effciently be applied for the modeling of thickener for dewatering of flotation tailing.
基金financially supported by the National Natural Science Foundation of China(Grant Nos.51709170 and 51979167)the Ministry of Industry and Information Technology of China(Mooring position technology:floating support platform engineering(II))the Shanghai Sailing Program(Grant No.17YF1409700)
文摘In this paper,a methodology for designing mooring system deployment for vessels at varying water depths is proposed.The Non-dominated Sorting Genetic Algorithm-II(NSGA-II)is combined with a self-dependently developed vessel-mooring coupled program to find the optimal mooring system deployment considering both station-keeping requirements and the safety of the mooring system.Two case studies are presented to demonstrate the methodology by designing the mooring system deployments for a very large floating structure(VLFS)module and a semi-submersible platform respectively at three different water depths.It can be concluded from the obtained results that the mooring system can achieve a better station-keeping ability with relatively shorter mooring line when deployed in the shallow water.The safety factor of mooring line is mainly dominated by the maximum instantaneous tension increment in the shallow water,while the pre-tension has a decisive influence on the safety factor of the mooring line in the deep water.
文摘This paper presents an innovative Soft Design Science Methodology for improving information systems security using multi-layered security approach. The study applied Soft Design Science Methodology to address the problematic situation on how information systems security can be improved. In addition, Soft Design Science Methodology was compounded with mixed research methodology. This holistic approach helped for research methodology triangulation. The study assessed security requirements and developed a framework for improving information systems security. The study carried out maturity level assessment to determine security status quo in the education sector in Tanzania. The study identified security requirements gap (IT security controls, IT security measures) using ISO/IEC 21827: Systems Security Engineering-Capability Maturity Model (SSE-CMM) with a rating scale of 0 - 5. The results of this study show that maturity level across security domain is 0.44 out of 5. The finding shows that the implementation of IT security controls and security measures for ensuring security goals are lacking or conducted in ad-hoc. Thus, for improving the security of information systems, organisations should implement security controls and security measures in each security domain (multi-layer security). This research provides a framework for enhancing information systems security during capturing, processing, storage and transmission of information. This research has several practical contributions. Firstly, it contributes to the body of knowledge of information systems security by providing a set of security requirements for ensuring information systems security. Secondly, it contributes empirical evidence on how information systems security can be improved. Thirdly, it contributes on the applicability of Soft Design Science Methodology on addressing the problematic situation in information systems security. The research findings can be used by decision makers and lawmakers to improve existing cyber security laws, and enact laws for data privacy and sharing of open data.
基金supported by the National Natural Science Foundation of China(71702072 71811540414+2 种基金 71573115)the Natural Science Foundation for Jiangsu Institutions(BK20170810)the Ministry of Education of Humanities and Social Science Planning Fund(18YJA630008)
文摘Minimizing the impact of the mixed uncertainties(i.e.,the aleatory uncertainty and the epistemic uncertainty) for a complex product of compliant mechanism(CPCM) quality improvement signifies a fascinating research topic to enhance the robustness.However, most of the existing works in the CPCM robust design optimization neglect the mixed uncertainties, which might result in an unstable design or even an infeasible design. To solve this issue, a response surface methodology-based hybrid robust design optimization(RSM-based HRDO) approach is proposed to improve the robustness of the quality characteristic for the CPCM via considering the mixed uncertainties in the robust design optimization. A bridge-type amplification mechanism is used to manifest the effectiveness of the proposed approach. The comparison results prove that the proposed approach can not only keep its superiority in the robustness, but also provide a robust scheme for optimizing the design parameters.
文摘In this study,the enhancement of catalytic activity of ceria when modified with co-catalysts such as graphitic carbon nitride and silver was establishe d.The material was synthe sized using phytogenic combustion method,a green alternative to the traditional preparative routes.The catalyst was characterized using XRD,FTIR,SEM,EDX,XPS and TEM techniques.The synergistic effect of the composite CeO2/g-C3 N4/Ag was tested for catalytic reduction of 4-nitrophenol in the prese nce of sodium borohydride.The reaction was carried out at room tempe rature without any light source or exte rnal stirring.The individual and combined effects of four parameters,viz.,concentration of 4-NP,amount of catalyst,amount of NaBH4 and time for the reduction of reduction 4-NP were investigated using Box-Behnken design of response surface methodology(RSM).This statistical model was used to optimize the reaction conditions for maximum reduction of 4-NP.The optimum conditions for the reduction reaction are found to be 0.01 mmol/L 4-NP,15 mg catalyst,20 mg NaBH4 and 13.7 min time interval.
文摘Aircraft collaboration design is based on a unified set of schemas containing data and model representations and interfaces across disciplines.The aircraft design schema is a central data model that specifies the paradigm for the representation of a full lifecycle model of aircraft design.The construction of the schema currently lacks theoretical guidance.This paper designs a novel methodology to construct the aircraft design schema,a fully functional,logical,and selfconsistent methodology.The methodology defines a schema matrix that includes implementation strategies,principles,processes,meta-object facility,views,scenarios,and products.The aircraft conceptual design schema is constructed according to the methodology,which is a hands-on approach to help understand the concept and implementation.The features of the methodology are analyzed,and the methodology and the aircraft conceptual design schema are presented to address the pain points of multiple solution trade-offs,multiple iterations,and multidisciplinary coupling in aircraft conceptual collaboration design.
基金National Natural Science Foundation of China(No.51863020)。
文摘As a kind of natural fiber,ramie fiber has distinctive advantages in textile application,but the application is limited due to the traditional degumming mode.Compared with the traditional degumming process,the microbial degumming process has many advantages.To obtain the optimal conditions for degumming ramie with Bacillus subtilis DZ_(5)(BS DZ_(5)),a combined statistical approach of orthogonal array design(OAD)and response surface methodology(RSM)was used.The influences of initial pH of the bacteria medium,culture temperature,shaking speed,degumming time and inoculum size on submerged fermentation degumming were evaluated by using fractional factorial design.The main factors in the analysis were culture temperature,shaking speed and initial pH.The residual gum mass fraction was used as the optimization index,and the optimal conditions for degumming were determined by central composite design and RSM.Thus with only a limited number of experiments,an optimal ramie microbial degumming condition was found as the culture temperature of 40℃,the initial pH in the culture medium of 8.5,the shaking speed of 205 r/min,the degumming time of 96 h and the inoculum size of 5%.After microbial degumming of ramie under the optimal conditions,there was only 10.6%residual gum by mass in the fiber.In addition,the effective degumming of BS DZ_(5)was also confirmed by a scanning electron microscope(SEM).
文摘An intelligent response surface methodology (IRSM) was proposed to achieve the most competitive metal forming products, in which artificial intelligence technologies are introduced into the optimization process. It is used as simple and inexpensive replacement for computationally expensive simulation model. In IRSM, the optimal design space can be reduced greatly without any prior information about function distribution. Also, by identifying the approximation error region, new design points can be supplemented correspondingly to improve the response surface model effectively. The procedure is iterated until the accuracy reaches the desired threshold value. Thus, the global optimization can be performed based on this substitute model. Finally, we present an optimization design example about roll forming of a "U" channel product.
文摘<span style="font-family:Verdana;">The Building Information Modeling (BIM) methodology considers the representation of the building as a virtual BIM model and its main concept is to centralize all the information generated throughout the development of the project. Structural design involves a set of tasks, namely, structure definition, structural analyses, and after the generation of drawings and technical documentation. In all processes, it is required confidence in data transferred between the BIM systems used, and to support this, a high level of interoperability is claimed. The present study aims to evaluate the degree of interoperability between the BIM-based platforms, ArchiCAD (Graphisoft), Revit (Autodesk), and ETABS (CSI). Two-way data flows between these systems were explored using distinct transfer strategies: add-in applications;Industry Foundation Classes (IFC) standard data format. The research made allows identifying the most appropriate procedure to be adopted by structural engineers, given the interoperability limitations verified, enabling the establishment of a practical guide of sequential procedures on the development of structural designs using BIM tools.</span>
基金financial support from the National High Technology Research and Development Program 863(2011AA05A204)National Natural Science Foundation of China(U1361202)
文摘Isoamylene from the Fischer-Tropsch syncrude can be transformed to valuable fuel oxygenate additives through an equilibrium limited etherification reaction with methanol. A reactive distillation process is established to increase isoamylene conversion. Facing the challenge of improving product purity at the same time, an equilibrium stage model based design methodology is proposed and illustrated step-by-step for converting the Fischer-Tropsch C_5 olefins to tert-amyl methyl ether(TAME) process by using Aspen Plus. Under the guide of the proposed methodology, the design leads to a TAME product purity of higher than 95% and an isoamylene conversion of higher than 90%. The etherification kinetics over Amberlyst 35 is also studied within a temperature range of 60 ℃ to 75 ℃ to shed more light on the feasibility of process development. The methodology provides an effective reactive distillation column design to achieve the target reactant conversion and product purity simultaneously.
基金The Project Supported by National Science Foundation of China.
文摘Aiming at the problems cased by the fast increase of industry and popula-tion in China,the paper cxpounds the conceptual connotation of urban dcsign and theinteraction between urban form and design,sums up the“top-down”and“bottom-up”urban design approaches in history,and points out that subject of urban design——as anavailable approach to cope with the problems of building cities——should be put forwardin China as quickly as possible.
基金jointly supported by the National Key Research and Development Program of China(2022YFC2106300)the National Nature Science Foundation of China(U2267226).
文摘This study employed the Box-Behnken design in response surface methodology(RSM)to optimize predistillation and pressurized distillation column parameters in methanol distillation.Statistical and fittinganalyses demonstrated the effects of operational parameters and their interactions on product purity and operating costs.Results showed that for methanol mass fraction in the product,the top distillate of the predistillation column(D_(1)),the interaction between D_(1) and the top distillate of the pressurized distillation column(D_(2)),and the interaction between the theoretical plates of the pressurized distillation column(N_(2))and its refluxratio(R_(2))significantlyaffected the outcome,in addition to pressurized distillation column parameters.Acetone mass fraction was mainly influencedby predistillation column parameters and their interactions,with minimal relation to the pressurized distillation column.Operating costs were primarily affected by the refluxratio(R),withdrawal(D)of both columns,and their interactions.Optimization strategies involved increasing theoretical plates and reducing refluxratios compared to the initial plan,achieving energy-saving and consumption-reduction goals.The process required the pressurized distillation column‘s methanol mass fraction to exceed 99.80%,acetone mass fraction below 2×10^(-8),and formaldehyde mass fraction below 5×10^(-9),with a feed rate of 6100 kg·h^(-1).Plans A,B,and C achieved energy-savings of 29.80%,21.78%,and 25.50%respectively,while ensuring separation efficiencyand product quality.This research provides theoretical and practical guidance for optimizing the methanol distillation process,helping to reduce energy consumption and production costs,thereby enhancing corporate competitiveness.
基金supported by the Royal National Institute for Deaf people (RNID)
文摘Probes are the interface between microsystems and bio-cells.The ideal interface is one-to-one interface.Though various research groups have been able to establish some sort of interfaces after many years of research,they are very crude.Neurons are millions in numbers,whereas the prostheses successfully built so far have only a few hundred probes at best.Creating an ef- fective interface is still far away.Though we have micro-and nano-technologies,we couldn't build a prosthesis with an effective resolution.Main reasons behind it are the type of probe being used and the poor design of the probe.To address this problem,we developed a methodology to design a probe and an array of probes with better resolution and less resistive donut probe.This methodology helps us to design a probe optimizing all the parameters.We presented our methodology through a design that is capable of 70 μm penetration inside the tissue.The tissue heating by our designed probe is only 0.411 °C.We also characterized the donut probe,which could be used by any research group to design a donut probe of their specific need.
基金Supported by Special Item for Guangxi Bagui Scholars(Guicaijiaohan [2017]143)
文摘[Objectives] The research aimed to optimize extraction process of Clerodendrum philippinum Schauer var. simplex Mlodenke total flavonoids( CPTF),and provide reference for its development and utilization. [Methods] Based on single-factor test,ethanol concentration,extraction temperature and extraction time were taken as independent variables,and total flavonoids yield was taken as dependent variable. The test was conducted according to central composite design principle. Multivariate linear regression and binomial equation fitting of the result were conducted,and extraction process of CPTF was optimized by using response surface methodology. [Results]The optimal extraction process of CPTF was as below: ethanol concentration 54. 76%,extraction temperature 83. 92℃,extraction time 102. 64 min,solid-liquid ratio 1:20,extraction for twice. [Conclusions] The extraction process of CPTF by central composite design-response surface methodology was simple and feasible,with reliable prediction result,which was suitable for industrial production.
