Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proo...Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.展开更多
AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 ...AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 and 2022,were retrieved from the Web of Science Core Collection.Bibliometric analyses were performed using VOSviewer and CiteSpace software to explore publication trends,as well as the contributions and collaborative networks of countries/regions,authors,institutions,and journals.RESULTS:The annual number of publications on strabismus showed a consistent upward trend.The United States(USA)maintained a leading position in this research field while Republic of Korea and China emerged as rapidly advancing contributors over the last decade.The University of California,Los Angeles ranked as the most productive institution,and Jonathan M.Holmes from USA was the most productive author.Journal of AAPOS was the leading journal with the most strabismus publications,whereas the two most highly cited articles were both published in Ophthalmology.Co-occurrence analysis identified pivotal keywords and burst terms,including intermittent exotropia(IXT),acute acquired comitant esotropia(AACE),functional magnetic resonance imaging(fMRI),and surgical treatment,which were confirmed as predominant and frontier topics.CONCLUSION:This study provides a comprehensive bibliometric analysis of strabismus research,revealing the evolution of research hotspots over the past 30y and outlining several cutting-edge directions for future investigation.展开更多
Rime ice is an effective winter ambient air pollution accumulator.Due to its higher ion content as compared to snow it is a non-negligible contributor to atmospheric deposition fluxes with potential environmental cons...Rime ice is an effective winter ambient air pollution accumulator.Due to its higher ion content as compared to snow it is a non-negligible contributor to atmospheric deposition fluxes with potential environmental consequences,particularly in mountain regions.Here we explore spatio-temporal patterns of rime formation as a proxy for the propensity of individual sites to form rime ice.We present the recent time trends in rime ice occurrence and thickness measured by 23 professional meteorological stations in the Czech Republic in 2002–2023.In an exploratory data analysis,we found high year-to-year variability in rime occurrence and thickness at all sites.According to the annual mean number of hours with rime detected,the stations situated at the highest altitudes are significantly different(higher)from the rest of the sites.The highest rime hour and thickness records by far were observed at the LYSA station in the Beskydy(Beskid)Mts situated at the exposed mountaintop and highly elevated above the surrounding terrain.For advanced statistical modelling of rime thickness,we used two generalised additive models that account for long-term trends(potentially nonlinear),seasonal and daily variability.In an expanded model we further considered the effect of the North Atlantic Oscillation(NAO)index.All the parameters included in the models proved to be statistically significant,although the strength of their effect differed.Factors affecting the rime formation(meteorology and terrain)are strongly site-specific and identification of the significance of individual influencing factors remains a challenging task for our future research.Here,we explore a rare long-term rime record with detailed temporal resolution from multiple uniformly measured sites,which significantly enhances our understanding of rime formation.Additionally,the rime record is from a temperate zone,where rime forms only during a small part of the year.展开更多
Background:Hemifacial spasm(HFS)is a neurological disorder characterized by involuntary facial muscle contractions,significantly impacting quality of life.This study aims to provide a comprehensive bibliometric analys...Background:Hemifacial spasm(HFS)is a neurological disorder characterized by involuntary facial muscle contractions,significantly impacting quality of life.This study aims to provide a comprehensive bibliometric analysis of global research trends,collaborations,and scientific contributions in the field of HFS,addressing publication patterns,influential authors and institutions,and prominent research topics from 1999 to 2024.Methods:We conducted a bibliometric analysis based on 1,884 publications retrieved from the Web of Science Core Collection using the keyword"Hemifacial Spasm."Data analysis and visualization were performed using Microsoft Excel,R/Bibliometrix,Scimago Graphica,VOSviewer,Pajek,and CiteSpace.Parameters assessed included publication trends,author collaborations,institutional contributions,core journals,citation metrics,and keyword clusters.Results:Among the analyzed publications,1,646 were original research articles,and 238 were reviews,involving 6,063 researchers and citing 25,252 references.The United States,China,and Japan were identified as leading contributing countries,with prominent institutions including Shanghai Jiao Tong University,Sungkyunkwan University,and the University of Pittsburgh.Top authors by publication count were Li Shiting,Park Kwan,and Zhong Jun,whereas Peter J.Jannetta,Albert R.Møller,and Janko Jankovic were most frequently cited.Core journals,identified via Bradford’s Law,included Acta Neurochirurgica,World Neurosurgery,and Journal of Neurosurgery.Keyword analysis highlighted focal research areas:"hemifacial spasm","microvascular decompression",and"trigeminal neuralgia".Conclusion:This bibliometric study provides critical insights into the evolution of research on HFS,highlighting key contributors,institutional influence,and research hotspots.The findings underscore ongoing collaborative opportunities and essential areas for future research exploration.展开更多
Maize yield is critically endangered by diseases throughout its growth cycle,posing significant risks to food security.The spatial and temporal dynamics of maize yield loss and the rate of yield loss attributable to t...Maize yield is critically endangered by diseases throughout its growth cycle,posing significant risks to food security.The spatial and temporal dynamics of maize yield loss and the rate of yield loss attributable to these threats on a regional scale have been challenging to ascertain due to scarce continuous observation data.This study compiled county-level data on maize yield and yield loss across China's six primary cropping regions over twenty years from 1999 to 2018.These include the Spring-sown area of Northern China(1-NC),the Summer-sown Huang-Huai-Hai Plain(2-HHP),the Southwest Mountain(3-SM),the Southern Hilly(4-SH),the Northwest Irrigated(5-NI),and the Qinghai-Tibet Plateau Maize Regions(6-QTP).We identified 15 major diseases affecting these regions.The annual average yield loss due to maize diseases in the regions 1-NC,2-HHP,3-SM,4-SH,5-NI,and 6-QTP were 0.40,0.58,0.12,0.05,0.04 and<0.01 million tons,respectively,and the corresponding average yield loss rate(the ratio of yield loss to total yield)in these regions was 0.63,0.90,0.65,0.63,0.44,and 0.05.The yield loss due to all diseases increased for three regions in 3-SM,4-SH and 5-NI.The yield loss rate due to diseases significantly increased in region 4-SH and 5-NI.Predominantly,maize leaf blight has become the most significant threats.In region 1-NC,maize head smut(D1)and maize leaf blight(D2)were the primary diseases.In region 2-HHP,maize leaf blight(D2),maize rust(D3),maize brown spot(D5),Curvularia leaf spot(D7),and maize virus disease(D14)were the key pathogens.Bivariate trend analysis(joint analysis of yield loss and loss rate trends)indicated that maize head smut(D1)decreased significantly in 1-NC,while in 2-HHP,six diseases showed a significant decrease in both yield loss and loss rate,namely sheath blight(D4),brown spot(D5),root rot(D11),downy mildew(D12)and virus disease(D14).By providing a long-term,national-scale perspective,this study not only supports the development of broad management strategies but also guides the creation of precise,region-specific control protocols to safeguard maize production.展开更多
Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Fa...Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Factors Surveillance)conducted between 2010 and 2018,a total of 645,420 adult participants(97,741 in 2010;175,749 in 2013;187,777 in 2015;and 184,153 in 2018)were included in the trend analysis.Linear and logistic regression models were utilized to assess trends in sleep duration.Results In 2018,the estimated overall mean sleep duration among the Chinese adult population was7.58(SD,1.45)hours per day,with no significant trend from 2010.A significant increase in short sleep duration(≤6 hours)was observed in the total population,from 15.3%(95%CI:14.1%–16.5%)in 2010 to18.5%(95%CI:17.7%–19.3%)in 2018(P<0.001).Similarly,the trend in long sleep duration(>9 hours)was also significant,increasing in weighted prevalence from 7.2%(95%CI:6.3%–8.1%)in 2010 to 9.0%(95%CI:8.2%–9.9%)in 2018(P<0.001).Conclusion The prevalence of both short and long sleep durations significantly increased among Chinese adults from 2010 to 2018,highlighting the urgency of health initiatives to promote optimal sleep duration in China.展开更多
In this study,we use observations from the Sounding of the Atmosphere using Broadband Emission Radiometry(SABER)instrument onboard the Thermosphere–Ionosphere–Mesosphere Energetics and Dynamics(TIMED)satellite to de...In this study,we use observations from the Sounding of the Atmosphere using Broadband Emission Radiometry(SABER)instrument onboard the Thermosphere–Ionosphere–Mesosphere Energetics and Dynamics(TIMED)satellite to develop and apply a new local-time binning method to investigate the long-term evolution of mesospheric water vapor at high latitudes.The proposed method accounts for the gradual local-time drift of the SABER orbit by aligning seasonal observation windows and selecting samples observed at similar local times.This approach minimizes tidal aliasing and ensures more consistent sampling,yielding more reliable estimates of long-term water vapor trends at high latitudes.The results show that drying signals primarily appear in the polar regions.However,in the southern hemisphere,a drying trend is observed only in autumn,whereas winter and summer mainly show moistening trends.In contrast,the northern hemisphere exhibits drying signals in the polar regions during all seasons,showing a clear seasonal asymmetry.Additionally,the water vapor trend in the northern hemisphere is particularly pronounced in February(late winter),with moistening reaching up to+2.0 ppmv.The winter in the southern hemisphere(July–August)also shows moistening,but the trend is still weaker than in the northern hemisphere.These differences highlight the strong moistening trend in the northern hemisphere during winter and underscore the significant asymmetry in seasonal water vapor changes between the two hemispheres.These findings emphasize the limitations of water vapor trend estimates across different seasons and latitudes.Moreover,they provide new insights into the spatiotemporal variability associated with tidal structures,underscoring the importance of optimizing local-time sampling strategies for reliable long-term trend detection.展开更多
BACKGROUND Diverticular disease of the intestine is a major gastrointestinal cause of mortality in the United States and the world.It is one of the most common gastrointestinal conditions responsible for hospital admi...BACKGROUND Diverticular disease of the intestine is a major gastrointestinal cause of mortality in the United States and the world.It is one of the most common gastrointestinal conditions responsible for hospital admissions.AIM To identify mortality trends of diverticular disease among adults in the United States,examining regional and demographic variations,as these have not been previously studied.These trends are highly beneficial to studying disease burden and vulnerable populations.METHODS Diverticular disease-related mortality data were extracted as age-adjusted mortality rates(AAMRs)from death certificate data of the CDC WONDER database using International Statistical Classification of Diseases and Related Health Problems-10th Revision codes K57.0 to K57.9 from 1999 to 2020 in adults≥45 years of age per 100000 population.These AAMRs were stratified by gender,ethnicity,and demographics and analyzed using Joinpoint regression to determine annual percent changes(APCs)and assess trend changes.RESULTS Between 1999 and 2020,a total of 114044 diverticular disease-related deaths were reported among adults≥45 years of age.Our analysis reports progressive decline in mortality with AAMR decreasing from 6.7 in 1999 to 6.1 in 2003[APC:-2.60;95%confidence interval(CI):-3.79 to-0.33],after which it further declined to 3.6 in 2013(APC:-5.16;95%CI:-7.26 to-4.74),with a minimal decrease to 3.5 in 2020(APC:-0.65;95%CI:-1.87 to 1.51).Women had a higher AAMR(4.8)than men(3.8)throughout the study period.The racial analysis reported the highest overall AAMR in non-Hispanic(NH)Whites(4.7),followed by NH Black or African American(3.9),Hispanic or Latino(3.1),and Asian or Pacific Islander(1.5),with unreliable data for the American Indian or Alaska Native population.States in the top 90th percentile,such as Wyoming and Vermont,had approximately double the AAMRs compared to states in the bottom 10th percentile.The mortality rate also exhibited regional disparities,with an overall AAMR higher in the Midwest and West regions(4.7)compared to the Northeast and South regions(4.2),and higher in nonmetropolitan areas(5.4)compared to metropolitan areas(4.2).CONCLUSION Although the annual mortality of diverticular disease has decreased since 1999,there are certain demographic and regional disparities,with mortality rates higher in women,NH White and NH Black adults,Western regions,and nonmetropolitan areas.Further research is needed to identify factors responsible for these disparities and plan appropriate interventions.展开更多
Objective The Asia-Pacific region has a high chronic obstructive pulmonary disease(COPD)burden,but studies on its trends are limited.Using the Global Burden of Disease(GBD)2019 data,we analyzed COPD trends in 36 count...Objective The Asia-Pacific region has a high chronic obstructive pulmonary disease(COPD)burden,but studies on its trends are limited.Using the Global Burden of Disease(GBD)2019 data,we analyzed COPD trends in 36 countries and territories from 1990 to 2019 and predicted future incidence trends through 2034.Methods COPD data by age and sex from the GBD 2019 database were analyzed for incidence,prevalence,mortality,and disability-adjusted life years(DALY)rates from 1990 to 2019.Joinpoint regression identified significant annual trends,and age-standardized incidence rates were predicted through 2034 using age-period-cohort models.Results The incidence,prevalence,mortality,and disease burden of COPD have been decreasing,and the incidence rates will continue to decrease or remain stable until 2034 in most selected countries and territories,except for a few Southeastern Asian countries.The Lao People’s Democratic Republic and Vietnam are projected to experience an increase in COPD incidence from 165.3 per 100,000 in 2019 to 177 per 100,000 in 2034 and from 179.9 per 100,000 in 2019 to 192.5 per 100,000 in 2034,respectively.Older males had a higher incidence than any other sex or age group.The sex gap in incidence rates continues to widen,though it is smaller and less significant in the younger age group than in those in the older one.Conclusion COPD rates are expected to decline until 2034 but remain a health risk,especially in countries with rising rates.Urgent action on tobacco control,air pollution,and public education is needed.展开更多
Glaucoma,a degenerative optic neuropathy,causes retinal ganglion cell(RGC)apoptosis and irreversible vision loss.Current therapies often fail to stop disease progression despite lowering intraocular pressure,the main ...Glaucoma,a degenerative optic neuropathy,causes retinal ganglion cell(RGC)apoptosis and irreversible vision loss.Current therapies often fail to stop disease progression despite lowering intraocular pressure,the main risk factor.Thus,neuroprotective strategies have gained interest.We performed a bibliometric analysis to determine global publishing trends and relationships among prolific authors,publications,institutions,funding agencies,and journals.We also analyzed author keywords to identify research hotspots in glaucoma neuroprotection.Further,based on keyword analysis,we reviewed most recent literature to understand mechanistic pathways underlying glaucomarelated pathophysiological responses leading to RGC loss.Bibliographic data were sourced from Scopus.Basic bibliographic features were characterized using Scopus’s functions.VOSviewer was used for mapping and visualizing bibliometric networks.The analysis included trends in publications since 2000,the most prolific countries,institutions,authors,and the strength of their linkages.A significant increase in publication output over the past two decades was noted.The United States leads in funding support,research output,and citation links,followed by China and the UK.Among the top 10 most cited authors,three are from Japanese institutions.Keyword analysis shows a focus on molecular targets related to ischemia,excitotoxicity,inflammation,and oxidative stress,with fewer emerging drug candidates and limited clinical trials.Based on the most recent literature,emerging molecular targets underlying these key pathophysiological mechanisms are summarized.In conclusion,while pathophysiology and molecular mechanisms are the current focus,there is not much progress in developing new drug candidates and conducting clinical trials.展开更多
Atrial fibrillation(AF)/atrial flutter(AFL)is the most common sustained cardiac arrhythmia.The known risk factors for developing AF/AFL include age,structural heart disease,hypertension,diabetes mellitus,or hyperthyro...Atrial fibrillation(AF)/atrial flutter(AFL)is the most common sustained cardiac arrhythmia.The known risk factors for developing AF/AFL include age,structural heart disease,hypertension,diabetes mellitus,or hyperthyroidism.This study aims to attribute the trends in AF/AFL-related mortalities over the past two decades 1999-2020 concerning race and sex and disparity among them.To the best of our knowledge,this is the first study that estimates the trends and mortality due to AF/AFL from 1999-2020 in older adults in the United States.In this 21-year analysis of mortality data,we found a constant increase in mortality rates due to AF/AFL in older adults.From 1999 to 2020,the overall mortality in older adults aged 65 and above,regardless of sex and race,is found to be almost doubled i.e.about a 50.2%increase in the number of deaths due to AF/AFL.Furthermore,other confounding risk factors such has obesity,prior myocardial infarction,inflammation,hypertension,birth weight,diabetes mellitus,hyperthyroidism,hormone replacement therapy in menopausal women increases the risk in the occurrence or recurrent occurrence of AF.展开更多
The Pearl River Delta(PRD)region has been identified as a significant hotspot of wet ammonium deposition.However,the absence of long-term monitoring data in the area hinders the comprehension of the historical trends ...The Pearl River Delta(PRD)region has been identified as a significant hotspot of wet ammonium deposition.However,the absence of long-term monitoring data in the area hinders the comprehension of the historical trends and changes in wet NH_(4)^(+)-N deposition in response to emissions,which interferes with the ability to make effective decisions.This study has analyzed the long-term trends of wet NH_(4)^(+)-N deposition flux and has quantified the effect of anthropogenic emissions and meteorological factors at a typical urban site and a typical forest site in the PRD region from 2009 to 2020.It revealed a significant decreasing trend in wet NH_(4)^(+)-N flux in both the typical urban and forest areas of the PRD region,at-6.2%/year(p<0.001)and-3.3%/year(p<0.001),respectively.Anthropogenic emissions are thought to have contributed 47%–57%of the wet NH_(4)^(+)-N deposition trend over the past 12 years compared to meteorological factors.Meteorological conditions dominated the interannual fluctuations in wet NH_(4)^(+)-N deposition with an absolute contribution of 46%–52%,while anthropogenic emissions change alone explained 10%–31%.NH_(3)emissions have the greatest impact on the urban area among anthropogenic emission factors,while SO_(2)emissions have the greatest impact on the forest area.Additionally,precipitation was identified as the primary meteorological driver for both sites.Our findings also imply that the benefits of NH_(3)emissions reductions might not immediately emerge due to interference from weather-related factors.展开更多
BACKGROUND Barrett's esophagus(BE)is a known premalignant precursor to esophageal adenocarcinoma(EAC).The prevalence rates continue to rise in the United States,but many patients who are at risk of EAC are not scr...BACKGROUND Barrett's esophagus(BE)is a known premalignant precursor to esophageal adenocarcinoma(EAC).The prevalence rates continue to rise in the United States,but many patients who are at risk of EAC are not screened.Current practice guidelines include male gender as a predisposing factor for BE and EAC.The population-based clinical evidence regarding female gender remains limited.AIM To study comparative trends of gender disparities in patients with BE in the United States.METHODS A nationwide retrospective study was conducted using the 2009-2019 National Inpatient Sample(NIS)database.Patients with a primary or secondary diagnosis code of BE were identified.The major outcome of interest was determining the gender disparities in patients with BE.Trend analysis for respective outcomes for females was also reported to ascertain any time-based shifts.RESULTS We identified 1204190 patients with BE for the study period.Among the included patients,717439(59.6%)were men and 486751(40.4%)were women.The mean age was higher in women than in men(67.1±0.4 vs 66.6±0.3 years,P<0.001).The rate of BE per 100000 total NIS hospitalizations for males increased from 144.6 in 2009 to 213.4 in 2019(P<0.001).The rate for females increased from 96.8 in 2009 to 148.7 in 2019(P<0.001).There was a higher frequency of obesity among women compared to men(17.4%vs 12.6%,P<0.001).Obesity prevalence among females increased from 12.3%in 2009 to 21.9%in 2019(P<0.001).A lower prevalence of smoking was noted in women than in men(20.8%vs 35.7%,P<0.001).However,trend analysis showed an increasing prevalence of smoking among women,from 12.9%in 2009 to 30.7%in 2019(P<0.001).Additionally,there was a lower prevalence of alcohol abuse,Helicobacter pylori(H.pylori),and diabetes mellitus among females than males(P<0.001).Trend analysis showed an increasing prevalence of alcohol use disorder and a decreasing prevalence of H.pylori and diabetes mellitus among women(P<0.001).CONCLUSION The prevalence of BE among women has steadily increased from 2009 to 2019.The existing knowledge concerning BE development has historically focused on men,but our findings show that the risk in women is not insignificant.展开更多
From February 7 to 10,Creativeworld yet again served as the most important international stage for the latest trends in hobby,arts and crafts.Above all,the Trends 2025 area in Hall 1.2—once more curated by Stilbü...From February 7 to 10,Creativeworld yet again served as the most important international stage for the latest trends in hobby,arts and crafts.Above all,the Trends 2025 area in Hall 1.2—once more curated by Stilbüro Bora.Herke.Palmisano—offered an overview of the most important developments and invited visitors to take a playful stroll through the city,the garden,and the forest.展开更多
Objective:This study aimed to analyze the temporal trends in cancer mortality in China from 2013-2021 and project the future trends through 2030.Methods:This study was based on the China Causes of Death Surveillance D...Objective:This study aimed to analyze the temporal trends in cancer mortality in China from 2013-2021 and project the future trends through 2030.Methods:This study was based on the China Causes of Death Surveillance Dataset,which covers 2.37 billion person-years.Age-standardized mortality rates(ASMRs)were calculated using Segi’s world standard population and the trends were evaluated via Joinpoint regression.Bayesian age-period-cohort models were used for mortality projections.Contributions of demographic changes(population size and age structure)and risk factors to the mortality burden were quantified using the decomposition analysis.Results:The combined ASMRs for all cancers decreased annually by 2.3%,driven by significant declines in esophageal(4.8%),stomach(4.5%),and liver cancers(2.7%).In contrast,the pancreatic and prostate cancer ASMRs increased by 2.0% and 3.4% annually,respectively.Urban areas demonstrated a more rapid decline in the combined ASMRs for all cancers[average annual percent change(AAPC)=-3.0% in urban areas vs.-2.0% in rural areas],highlighting persistent disparities.Population aging contributed 20%-50% to death increases between 2013 and 2021.The combined ASMRs for all cancers,like the findings of temporal trend analyses,will continue to decrease and the regional(urban and rural)difference is projected to simulate that of the temporal trend through 2030.In fact,cancer deaths are projected to reach 2.4 million by 2030.Conclusions:The cancer burden in China is facing the dual challenges of population aging and urban-rural disparities.It is necessary to prioritize rural screening,control risk factors,such as smoking and diet,and integrate more efficacious cancer prevention and control programmes into the policy to reduce mortality in the future.展开更多
Childhood neuroblastoma,a leading cause of cancer-related mortality in young children,accounts for approximately 8%-10%of pediatric cancers1.Originating from neural crest cells of the sympathetic nervous system,these ...Childhood neuroblastoma,a leading cause of cancer-related mortality in young children,accounts for approximately 8%-10%of pediatric cancers1.Originating from neural crest cells of the sympathetic nervous system,these tumors affect primarily children younger than 5 years of age and are often diagnosed in advanced stages,because of their aggressive nature and vague early symptoms2-4.展开更多
Objectives:This study aims to evaluate the current state of acupuncture randomized controlled trials(RCTs),their impact on guidelines,and future development trends,providing a reference for future re-search directions...Objectives:This study aims to evaluate the current state of acupuncture randomized controlled trials(RCTs),their impact on guidelines,and future development trends,providing a reference for future re-search directions.Methods:Search for acupuncture-related RCT articles in the Web of Science Core Collection and con-firm their guideline inclusion on Google Scholar.Analyze study characteristics to predict future research directions.Results:The analysis covered 1422 articles,reflecting a substantial rise in publications from 77 articles between 1993 and 2002 to 960 articles between 2013 and 2022.The Western Pacific region led in pub-lication numbers with 622 articles(43.7%),followed by Europe(466 articles;32.8%),Americas(250 articles;17.6%),Eastern Mediterranean(62 articles;4.4%),and Southeast Asia(22 articles;1.5%),with Africa showing a research void.Regrettably,only 29.6%(421 articles)were incorporated into guidelines.The low rate of inclusion of research results in guidelines and the uneven distribution of research fields are particularly prominent.From 1993 to 2002,there were 77 articles,among which 51(66.2%)were included in the guidelines;from 2003 to 2012,there were 385 articles,with 202(52.5%)included;from 2013 to 2022,there were 960 articles,and only 168(17.5%)were included,showing a decreasing trend in the inclusion rate year by year.Regarding geographical distribution,1167 articles were from the East-ern Hemisphere,with 326(27.9%)included;255 were from the Western Hemisphere,and 95(37.3%)were included.Regionally,179 articles(42.5%)from Europe were included,140(33.3%)from the West-ern Pacific,95(22.6%)from the Americas,6(1.4%)from the Eastern Mediterranean,and 1(0.2%)from Southeast Asia.China,the United States,and Germany were the top publishing countries,with consis-tent growth in countries like China,South Korea,Spain,Brazil,Turkey,and Iran.Noteworthy researchers such as Cesar Fernandez-de-las-Penas,Zhi-shun LIU,Jing-wen YANG,Cun-zhi LIU,Li-xing LAO,Stefan N Willich,and Benno Brinkhaus have collaborated on research in areas such as pain management,cognitive impairments,insomnia,digestive system diseases,and urinary system diseases.There has been a partic-ular increase in research focus on neck pain and myofascial trigger points.展开更多
Objective:This paper conducts a bibliometric analysis of the literature on neck pain research from 2000 to 2025,aiming to comprehensively and systematically understand the research landscape,hotspots,and frontier tren...Objective:This paper conducts a bibliometric analysis of the literature on neck pain research from 2000 to 2025,aiming to comprehensively and systematically understand the research landscape,hotspots,and frontier trends in this field,providing a reference for future research directions.Methods:Data were sourced from the Web of Science Core Collection,with the search term TI=“neck pain,”covering the time span from 2000 to 2025,resulting in 2746 articles.Software such as CiteSpace V6.3.R1 and VOSviewer 1.6.20 was used to analyze publication volume,countries,authors,institutions,keywords,and co-citation networks.Results:The number of publications in neck pain research has been increasing year by year,indicating a rising level of research activity.Authors like Falla,D,Jull,G,and institutions such as Univ Queensland and Univ Toronto have significant influence in this field.Co-occurrence analysis of keywords shows that“neck pain,”“low back pain,”and“disability index”are high-frequency keywords,reflecting research hotspots such as the characteristics and treatment of neck pain and its interrelation with pain in other regions.Timeline analysis and keyword emergence analysis reveal the frontiers and development trends in this field,such as the growing attention on emerging therapeutic methods like“exercise therapy”and“dry needling,”while keywords like“intensity,”“individuals,”and“quality”indicate an increasing emphasis on personalization,precision,and quality control in the treatment process.Conclusion:The field of neck pain research is continuously expanding and deepening.Future research should further investigate the pathogenesis of neck pain,its associations with other conditions,the refinement of assessment methods,and the development of innovative rehabilitation strategies.Emphasis should also be placed on interdisciplinary collaboration to provide more robust theoretical foundations and practical guidance for the clinical treatment and rehabilitation management of neck pain.展开更多
With an optimised hall layout,progressive design collaborations,inspiring trends and AIdriven innovations,Heimtextil 2026 reacts to the current market situation–and offers the industry a reliable constant in challeng...With an optimised hall layout,progressive design collaborations,inspiring trends and AIdriven innovations,Heimtextil 2026 reacts to the current market situation–and offers the industry a reliable constant in challenging times.Under the motto‘Lead the Change’,the leading trade fair for home and contract textiles and textile design shows how challenges can be turned into opportunities.From 13 to 16 January,more than 3,100 exhibitors from 65 countries will provide a comprehensive market overview with new collections and textile solutions.As a knowledge hub,Heimtextil delivers new strategies and concrete solutions for future business success.展开更多
Background:Over the past 15 years,research has emphasized the crucial role of the gut microbiota in metabolism and its potential association with osteoporosis.Given the increasing interest in this area,a bibliometric ...Background:Over the past 15 years,research has emphasized the crucial role of the gut microbiota in metabolism and its potential association with osteoporosis.Given the increasing interest in this area,a bibliometric analysis is essential to comprehensively understand the field.Methods:Literature published between 2009 and 2023 was retrieved from the Web of Science.CiteSpace,a tool for visual analysis,was employed to examine various aspects of the research,including the annual number of publications,contributing institutions,journals,authors,keywords,clusters,hotspots,and emerging frontiers.Results:The analysis included 1,075 articles from 80 countries,283 institutions,and 155 authors,reflecting the rapid growth of research in this field.PEOPLES R CHINA emerged as the most productive country,while the University of California System was the most active institution.Parameswaran,Narayanan had the highest number of publications,and LI JY and OHLSSON C were the most cited authors.Key keywords such as“gut microbiota,”“bone loss,”“bone mineral density,”“inflammation,”and“health”were identified,and keywords with strong citation bursts like“in vitro,”“inflammatory bowel disease,”and“bone mineral density”indicated emerging trends.Conclusion:This bibliometric analysis successfully identified research trends and hotspots,including the fecal microbiome,musculoskeletal studies,and postmenopausal women.Continued research in these areas will enhance our understanding of osteoporosis and may lead to the development of new treatments.The findings offer valuable insights for scholars aiming to conduct in-depth research in this field.展开更多
文摘Medical Data Mining published an article entitled Mapping the global research trends and hotspots on hypertensive nephropathy:A novel bibliometrics overview on 10 October 2025.The author confirmed this article’s proof on 28 September 2025 without any questions.However,on 13 November 2025,the Editorial Office of Medical Data Mining noticed an inconsistency between the data presented in the main text and Figure 1.Specifically,erroneous Figure 1 states“a total of 56,691 literatures were obtained through database search”,while the main text in the Search results section states“According to the search term,a total of 59,220 publications were retrieved from the database.”The authors acknowledge that the original version of Figure 1 was incorrect and have provided the revised,correct version in this corrigendum.The authors would like to assert that there is no change in the body text of the article.
基金Supported by National Natural Science Foundation of China(No.82020108006,No.81730025).
文摘AIM:To summarize publication trends in the field of strabismus over the past 30y and predict future research hotspots.METHODS:A total of 2915 English-language articles and reviews on strabismus,published between 1993 and 2022,were retrieved from the Web of Science Core Collection.Bibliometric analyses were performed using VOSviewer and CiteSpace software to explore publication trends,as well as the contributions and collaborative networks of countries/regions,authors,institutions,and journals.RESULTS:The annual number of publications on strabismus showed a consistent upward trend.The United States(USA)maintained a leading position in this research field while Republic of Korea and China emerged as rapidly advancing contributors over the last decade.The University of California,Los Angeles ranked as the most productive institution,and Jonathan M.Holmes from USA was the most productive author.Journal of AAPOS was the leading journal with the most strabismus publications,whereas the two most highly cited articles were both published in Ophthalmology.Co-occurrence analysis identified pivotal keywords and burst terms,including intermittent exotropia(IXT),acute acquired comitant esotropia(AACE),functional magnetic resonance imaging(fMRI),and surgical treatment,which were confirmed as predominant and frontier topics.CONCLUSION:This study provides a comprehensive bibliometric analysis of strabismus research,revealing the evolution of research hotspots over the past 30y and outlining several cutting-edge directions for future investigation.
基金financially supported by the Technological Agency of the Czech Republic (TAČR), Joint Grant No SS 02030031 ARAMISby the long-term strategic development financing of the Institute of Computer Science of the Czech Academy of Sciences (RVO 67985807)
文摘Rime ice is an effective winter ambient air pollution accumulator.Due to its higher ion content as compared to snow it is a non-negligible contributor to atmospheric deposition fluxes with potential environmental consequences,particularly in mountain regions.Here we explore spatio-temporal patterns of rime formation as a proxy for the propensity of individual sites to form rime ice.We present the recent time trends in rime ice occurrence and thickness measured by 23 professional meteorological stations in the Czech Republic in 2002–2023.In an exploratory data analysis,we found high year-to-year variability in rime occurrence and thickness at all sites.According to the annual mean number of hours with rime detected,the stations situated at the highest altitudes are significantly different(higher)from the rest of the sites.The highest rime hour and thickness records by far were observed at the LYSA station in the Beskydy(Beskid)Mts situated at the exposed mountaintop and highly elevated above the surrounding terrain.For advanced statistical modelling of rime thickness,we used two generalised additive models that account for long-term trends(potentially nonlinear),seasonal and daily variability.In an expanded model we further considered the effect of the North Atlantic Oscillation(NAO)index.All the parameters included in the models proved to be statistically significant,although the strength of their effect differed.Factors affecting the rime formation(meteorology and terrain)are strongly site-specific and identification of the significance of individual influencing factors remains a challenging task for our future research.Here,we explore a rare long-term rime record with detailed temporal resolution from multiple uniformly measured sites,which significantly enhances our understanding of rime formation.Additionally,the rime record is from a temperate zone,where rime forms only during a small part of the year.
基金supported by grants from the National Natural Science Foundation of China(No.82271426).
文摘Background:Hemifacial spasm(HFS)is a neurological disorder characterized by involuntary facial muscle contractions,significantly impacting quality of life.This study aims to provide a comprehensive bibliometric analysis of global research trends,collaborations,and scientific contributions in the field of HFS,addressing publication patterns,influential authors and institutions,and prominent research topics from 1999 to 2024.Methods:We conducted a bibliometric analysis based on 1,884 publications retrieved from the Web of Science Core Collection using the keyword"Hemifacial Spasm."Data analysis and visualization were performed using Microsoft Excel,R/Bibliometrix,Scimago Graphica,VOSviewer,Pajek,and CiteSpace.Parameters assessed included publication trends,author collaborations,institutional contributions,core journals,citation metrics,and keyword clusters.Results:Among the analyzed publications,1,646 were original research articles,and 238 were reviews,involving 6,063 researchers and citing 25,252 references.The United States,China,and Japan were identified as leading contributing countries,with prominent institutions including Shanghai Jiao Tong University,Sungkyunkwan University,and the University of Pittsburgh.Top authors by publication count were Li Shiting,Park Kwan,and Zhong Jun,whereas Peter J.Jannetta,Albert R.Møller,and Janko Jankovic were most frequently cited.Core journals,identified via Bradford’s Law,included Acta Neurochirurgica,World Neurosurgery,and Journal of Neurosurgery.Keyword analysis highlighted focal research areas:"hemifacial spasm","microvascular decompression",and"trigeminal neuralgia".Conclusion:This bibliometric study provides critical insights into the evolution of research on HFS,highlighting key contributors,institutional influence,and research hotspots.The findings underscore ongoing collaborative opportunities and essential areas for future research exploration.
基金supported by the National Key Research and Development Program of China,China(2022YFF1301801)Agricultural scientific and technological innovation project of Shandong Academy of Agricultural Sciences,China(333 Project)(06202214442066)+1 种基金Beijing Natural Science Foundation,China(5232018)Technology Innovation Project of Shandong Academy of Agricultural Sciences,China(06202214442062).
文摘Maize yield is critically endangered by diseases throughout its growth cycle,posing significant risks to food security.The spatial and temporal dynamics of maize yield loss and the rate of yield loss attributable to these threats on a regional scale have been challenging to ascertain due to scarce continuous observation data.This study compiled county-level data on maize yield and yield loss across China's six primary cropping regions over twenty years from 1999 to 2018.These include the Spring-sown area of Northern China(1-NC),the Summer-sown Huang-Huai-Hai Plain(2-HHP),the Southwest Mountain(3-SM),the Southern Hilly(4-SH),the Northwest Irrigated(5-NI),and the Qinghai-Tibet Plateau Maize Regions(6-QTP).We identified 15 major diseases affecting these regions.The annual average yield loss due to maize diseases in the regions 1-NC,2-HHP,3-SM,4-SH,5-NI,and 6-QTP were 0.40,0.58,0.12,0.05,0.04 and<0.01 million tons,respectively,and the corresponding average yield loss rate(the ratio of yield loss to total yield)in these regions was 0.63,0.90,0.65,0.63,0.44,and 0.05.The yield loss due to all diseases increased for three regions in 3-SM,4-SH and 5-NI.The yield loss rate due to diseases significantly increased in region 4-SH and 5-NI.Predominantly,maize leaf blight has become the most significant threats.In region 1-NC,maize head smut(D1)and maize leaf blight(D2)were the primary diseases.In region 2-HHP,maize leaf blight(D2),maize rust(D3),maize brown spot(D5),Curvularia leaf spot(D7),and maize virus disease(D14)were the key pathogens.Bivariate trend analysis(joint analysis of yield loss and loss rate trends)indicated that maize head smut(D1)decreased significantly in 1-NC,while in 2-HHP,six diseases showed a significant decrease in both yield loss and loss rate,namely sheath blight(D4),brown spot(D5),root rot(D11),downy mildew(D12)and virus disease(D14).By providing a long-term,national-scale perspective,this study not only supports the development of broad management strategies but also guides the creation of precise,region-specific control protocols to safeguard maize production.
基金supported by the National Natural Science Foundation of China(82341245,82371491)the Chinese Central Government(Key Project of Public Health Program)the National Key Research and Development Program of China(2018YFC1311706,2018YFC1311702)。
文摘Objective This study aimed to determine the temporal trends in sleep duration among Chinese adults.Methods In this series of repeated nationally representative cross-sectional surveys(China Chronic Disease and Risk Factors Surveillance)conducted between 2010 and 2018,a total of 645,420 adult participants(97,741 in 2010;175,749 in 2013;187,777 in 2015;and 184,153 in 2018)were included in the trend analysis.Linear and logistic regression models were utilized to assess trends in sleep duration.Results In 2018,the estimated overall mean sleep duration among the Chinese adult population was7.58(SD,1.45)hours per day,with no significant trend from 2010.A significant increase in short sleep duration(≤6 hours)was observed in the total population,from 15.3%(95%CI:14.1%–16.5%)in 2010 to18.5%(95%CI:17.7%–19.3%)in 2018(P<0.001).Similarly,the trend in long sleep duration(>9 hours)was also significant,increasing in weighted prevalence from 7.2%(95%CI:6.3%–8.1%)in 2010 to 9.0%(95%CI:8.2%–9.9%)in 2018(P<0.001).Conclusion The prevalence of both short and long sleep durations significantly increased among Chinese adults from 2010 to 2018,highlighting the urgency of health initiatives to promote optimal sleep duration in China.
基金supported by the National Key R&D Program of China(Grant No.2022YFF0503703)the National Natural Science Foundation of China(Grant Nos.42130203,42275133,and 42241135).
文摘In this study,we use observations from the Sounding of the Atmosphere using Broadband Emission Radiometry(SABER)instrument onboard the Thermosphere–Ionosphere–Mesosphere Energetics and Dynamics(TIMED)satellite to develop and apply a new local-time binning method to investigate the long-term evolution of mesospheric water vapor at high latitudes.The proposed method accounts for the gradual local-time drift of the SABER orbit by aligning seasonal observation windows and selecting samples observed at similar local times.This approach minimizes tidal aliasing and ensures more consistent sampling,yielding more reliable estimates of long-term water vapor trends at high latitudes.The results show that drying signals primarily appear in the polar regions.However,in the southern hemisphere,a drying trend is observed only in autumn,whereas winter and summer mainly show moistening trends.In contrast,the northern hemisphere exhibits drying signals in the polar regions during all seasons,showing a clear seasonal asymmetry.Additionally,the water vapor trend in the northern hemisphere is particularly pronounced in February(late winter),with moistening reaching up to+2.0 ppmv.The winter in the southern hemisphere(July–August)also shows moistening,but the trend is still weaker than in the northern hemisphere.These differences highlight the strong moistening trend in the northern hemisphere during winter and underscore the significant asymmetry in seasonal water vapor changes between the two hemispheres.These findings emphasize the limitations of water vapor trend estimates across different seasons and latitudes.Moreover,they provide new insights into the spatiotemporal variability associated with tidal structures,underscoring the importance of optimizing local-time sampling strategies for reliable long-term trend detection.
文摘BACKGROUND Diverticular disease of the intestine is a major gastrointestinal cause of mortality in the United States and the world.It is one of the most common gastrointestinal conditions responsible for hospital admissions.AIM To identify mortality trends of diverticular disease among adults in the United States,examining regional and demographic variations,as these have not been previously studied.These trends are highly beneficial to studying disease burden and vulnerable populations.METHODS Diverticular disease-related mortality data were extracted as age-adjusted mortality rates(AAMRs)from death certificate data of the CDC WONDER database using International Statistical Classification of Diseases and Related Health Problems-10th Revision codes K57.0 to K57.9 from 1999 to 2020 in adults≥45 years of age per 100000 population.These AAMRs were stratified by gender,ethnicity,and demographics and analyzed using Joinpoint regression to determine annual percent changes(APCs)and assess trend changes.RESULTS Between 1999 and 2020,a total of 114044 diverticular disease-related deaths were reported among adults≥45 years of age.Our analysis reports progressive decline in mortality with AAMR decreasing from 6.7 in 1999 to 6.1 in 2003[APC:-2.60;95%confidence interval(CI):-3.79 to-0.33],after which it further declined to 3.6 in 2013(APC:-5.16;95%CI:-7.26 to-4.74),with a minimal decrease to 3.5 in 2020(APC:-0.65;95%CI:-1.87 to 1.51).Women had a higher AAMR(4.8)than men(3.8)throughout the study period.The racial analysis reported the highest overall AAMR in non-Hispanic(NH)Whites(4.7),followed by NH Black or African American(3.9),Hispanic or Latino(3.1),and Asian or Pacific Islander(1.5),with unreliable data for the American Indian or Alaska Native population.States in the top 90th percentile,such as Wyoming and Vermont,had approximately double the AAMRs compared to states in the bottom 10th percentile.The mortality rate also exhibited regional disparities,with an overall AAMR higher in the Midwest and West regions(4.7)compared to the Northeast and South regions(4.2),and higher in nonmetropolitan areas(5.4)compared to metropolitan areas(4.2).CONCLUSION Although the annual mortality of diverticular disease has decreased since 1999,there are certain demographic and regional disparities,with mortality rates higher in women,NH White and NH Black adults,Western regions,and nonmetropolitan areas.Further research is needed to identify factors responsible for these disparities and plan appropriate interventions.
基金supported by a major project of the Zhejiang Natural Science Foundation(LD21G030001).
文摘Objective The Asia-Pacific region has a high chronic obstructive pulmonary disease(COPD)burden,but studies on its trends are limited.Using the Global Burden of Disease(GBD)2019 data,we analyzed COPD trends in 36 countries and territories from 1990 to 2019 and predicted future incidence trends through 2034.Methods COPD data by age and sex from the GBD 2019 database were analyzed for incidence,prevalence,mortality,and disability-adjusted life years(DALY)rates from 1990 to 2019.Joinpoint regression identified significant annual trends,and age-standardized incidence rates were predicted through 2034 using age-period-cohort models.Results The incidence,prevalence,mortality,and disease burden of COPD have been decreasing,and the incidence rates will continue to decrease or remain stable until 2034 in most selected countries and territories,except for a few Southeastern Asian countries.The Lao People’s Democratic Republic and Vietnam are projected to experience an increase in COPD incidence from 165.3 per 100,000 in 2019 to 177 per 100,000 in 2034 and from 179.9 per 100,000 in 2019 to 192.5 per 100,000 in 2034,respectively.Older males had a higher incidence than any other sex or age group.The sex gap in incidence rates continues to widen,though it is smaller and less significant in the younger age group than in those in the older one.Conclusion COPD rates are expected to decline until 2034 but remain a health risk,especially in countries with rising rates.Urgent action on tobacco control,air pollution,and public education is needed.
基金Supported by the Ministry of Higher Education(Malaysia)(No.FRGS/1/2023/SKK15/IMU/01/1)International Medical University[No.PHMS I-2023(01)].
文摘Glaucoma,a degenerative optic neuropathy,causes retinal ganglion cell(RGC)apoptosis and irreversible vision loss.Current therapies often fail to stop disease progression despite lowering intraocular pressure,the main risk factor.Thus,neuroprotective strategies have gained interest.We performed a bibliometric analysis to determine global publishing trends and relationships among prolific authors,publications,institutions,funding agencies,and journals.We also analyzed author keywords to identify research hotspots in glaucoma neuroprotection.Further,based on keyword analysis,we reviewed most recent literature to understand mechanistic pathways underlying glaucomarelated pathophysiological responses leading to RGC loss.Bibliographic data were sourced from Scopus.Basic bibliographic features were characterized using Scopus’s functions.VOSviewer was used for mapping and visualizing bibliometric networks.The analysis included trends in publications since 2000,the most prolific countries,institutions,authors,and the strength of their linkages.A significant increase in publication output over the past two decades was noted.The United States leads in funding support,research output,and citation links,followed by China and the UK.Among the top 10 most cited authors,three are from Japanese institutions.Keyword analysis shows a focus on molecular targets related to ischemia,excitotoxicity,inflammation,and oxidative stress,with fewer emerging drug candidates and limited clinical trials.Based on the most recent literature,emerging molecular targets underlying these key pathophysiological mechanisms are summarized.In conclusion,while pathophysiology and molecular mechanisms are the current focus,there is not much progress in developing new drug candidates and conducting clinical trials.
文摘Atrial fibrillation(AF)/atrial flutter(AFL)is the most common sustained cardiac arrhythmia.The known risk factors for developing AF/AFL include age,structural heart disease,hypertension,diabetes mellitus,or hyperthyroidism.This study aims to attribute the trends in AF/AFL-related mortalities over the past two decades 1999-2020 concerning race and sex and disparity among them.To the best of our knowledge,this is the first study that estimates the trends and mortality due to AF/AFL from 1999-2020 in older adults in the United States.In this 21-year analysis of mortality data,we found a constant increase in mortality rates due to AF/AFL in older adults.From 1999 to 2020,the overall mortality in older adults aged 65 and above,regardless of sex and race,is found to be almost doubled i.e.about a 50.2%increase in the number of deaths due to AF/AFL.Furthermore,other confounding risk factors such has obesity,prior myocardial infarction,inflammation,hypertension,birth weight,diabetes mellitus,hyperthyroidism,hormone replacement therapy in menopausal women increases the risk in the occurrence or recurrent occurrence of AF.
基金supported by the National Natural Science Foundation(Nos.42275107,42121004,and 42375109)the National Key Research and Development Plan(No.2023YFC3706202)+1 种基金the Foundational and Applied Basic Research in Guangzhou in 2023(No.2023A04J0251)the Special Fund Project for Science and Technology Innovation Strategy of Guangdong Province(No.2019B121205004).
文摘The Pearl River Delta(PRD)region has been identified as a significant hotspot of wet ammonium deposition.However,the absence of long-term monitoring data in the area hinders the comprehension of the historical trends and changes in wet NH_(4)^(+)-N deposition in response to emissions,which interferes with the ability to make effective decisions.This study has analyzed the long-term trends of wet NH_(4)^(+)-N deposition flux and has quantified the effect of anthropogenic emissions and meteorological factors at a typical urban site and a typical forest site in the PRD region from 2009 to 2020.It revealed a significant decreasing trend in wet NH_(4)^(+)-N flux in both the typical urban and forest areas of the PRD region,at-6.2%/year(p<0.001)and-3.3%/year(p<0.001),respectively.Anthropogenic emissions are thought to have contributed 47%–57%of the wet NH_(4)^(+)-N deposition trend over the past 12 years compared to meteorological factors.Meteorological conditions dominated the interannual fluctuations in wet NH_(4)^(+)-N deposition with an absolute contribution of 46%–52%,while anthropogenic emissions change alone explained 10%–31%.NH_(3)emissions have the greatest impact on the urban area among anthropogenic emission factors,while SO_(2)emissions have the greatest impact on the forest area.Additionally,precipitation was identified as the primary meteorological driver for both sites.Our findings also imply that the benefits of NH_(3)emissions reductions might not immediately emerge due to interference from weather-related factors.
文摘BACKGROUND Barrett's esophagus(BE)is a known premalignant precursor to esophageal adenocarcinoma(EAC).The prevalence rates continue to rise in the United States,but many patients who are at risk of EAC are not screened.Current practice guidelines include male gender as a predisposing factor for BE and EAC.The population-based clinical evidence regarding female gender remains limited.AIM To study comparative trends of gender disparities in patients with BE in the United States.METHODS A nationwide retrospective study was conducted using the 2009-2019 National Inpatient Sample(NIS)database.Patients with a primary or secondary diagnosis code of BE were identified.The major outcome of interest was determining the gender disparities in patients with BE.Trend analysis for respective outcomes for females was also reported to ascertain any time-based shifts.RESULTS We identified 1204190 patients with BE for the study period.Among the included patients,717439(59.6%)were men and 486751(40.4%)were women.The mean age was higher in women than in men(67.1±0.4 vs 66.6±0.3 years,P<0.001).The rate of BE per 100000 total NIS hospitalizations for males increased from 144.6 in 2009 to 213.4 in 2019(P<0.001).The rate for females increased from 96.8 in 2009 to 148.7 in 2019(P<0.001).There was a higher frequency of obesity among women compared to men(17.4%vs 12.6%,P<0.001).Obesity prevalence among females increased from 12.3%in 2009 to 21.9%in 2019(P<0.001).A lower prevalence of smoking was noted in women than in men(20.8%vs 35.7%,P<0.001).However,trend analysis showed an increasing prevalence of smoking among women,from 12.9%in 2009 to 30.7%in 2019(P<0.001).Additionally,there was a lower prevalence of alcohol abuse,Helicobacter pylori(H.pylori),and diabetes mellitus among females than males(P<0.001).Trend analysis showed an increasing prevalence of alcohol use disorder and a decreasing prevalence of H.pylori and diabetes mellitus among women(P<0.001).CONCLUSION The prevalence of BE among women has steadily increased from 2009 to 2019.The existing knowledge concerning BE development has historically focused on men,but our findings show that the risk in women is not insignificant.
文摘From February 7 to 10,Creativeworld yet again served as the most important international stage for the latest trends in hobby,arts and crafts.Above all,the Trends 2025 area in Hall 1.2—once more curated by Stilbüro Bora.Herke.Palmisano—offered an overview of the most important developments and invited visitors to take a playful stroll through the city,the garden,and the forest.
基金supported by the CAMS Innovation Fund for Medical Sciences(Grant No.2021-I2M-1-011)the Capital’s Funds for Health Improvement and Research(Grant No.CFH2024-2G-40214).
文摘Objective:This study aimed to analyze the temporal trends in cancer mortality in China from 2013-2021 and project the future trends through 2030.Methods:This study was based on the China Causes of Death Surveillance Dataset,which covers 2.37 billion person-years.Age-standardized mortality rates(ASMRs)were calculated using Segi’s world standard population and the trends were evaluated via Joinpoint regression.Bayesian age-period-cohort models were used for mortality projections.Contributions of demographic changes(population size and age structure)and risk factors to the mortality burden were quantified using the decomposition analysis.Results:The combined ASMRs for all cancers decreased annually by 2.3%,driven by significant declines in esophageal(4.8%),stomach(4.5%),and liver cancers(2.7%).In contrast,the pancreatic and prostate cancer ASMRs increased by 2.0% and 3.4% annually,respectively.Urban areas demonstrated a more rapid decline in the combined ASMRs for all cancers[average annual percent change(AAPC)=-3.0% in urban areas vs.-2.0% in rural areas],highlighting persistent disparities.Population aging contributed 20%-50% to death increases between 2013 and 2021.The combined ASMRs for all cancers,like the findings of temporal trend analyses,will continue to decrease and the regional(urban and rural)difference is projected to simulate that of the temporal trend through 2030.In fact,cancer deaths are projected to reach 2.4 million by 2030.Conclusions:The cancer burden in China is facing the dual challenges of population aging and urban-rural disparities.It is necessary to prioritize rural screening,control risk factors,such as smoking and diet,and integrate more efficacious cancer prevention and control programmes into the policy to reduce mortality in the future.
基金supported by grants from the National Natural Science Foundation of China(Grant No.82470544)the Fundamental Research Funds for the Central Universities(Grant No.226-2024-00153).
文摘Childhood neuroblastoma,a leading cause of cancer-related mortality in young children,accounts for approximately 8%-10%of pediatric cancers1.Originating from neural crest cells of the sympathetic nervous system,these tumors affect primarily children younger than 5 years of age and are often diagnosed in advanced stages,because of their aggressive nature and vague early symptoms2-4.
基金Supported by the National Natural Science Foundation of China:82074529Guangdong Province Famous Traditional Chinese Medicine Inheritance Studio Construction Project:Guangdong Traditional Chinese Medicine Office Letter 2023_108+1 种基金Sanming Project of Medicine in Shenzhen:SZZYSM202108013Hainan General Hospital Science and Technology Start-up Fund for Braught-in Talents:YJRC2022001。
文摘Objectives:This study aims to evaluate the current state of acupuncture randomized controlled trials(RCTs),their impact on guidelines,and future development trends,providing a reference for future re-search directions.Methods:Search for acupuncture-related RCT articles in the Web of Science Core Collection and con-firm their guideline inclusion on Google Scholar.Analyze study characteristics to predict future research directions.Results:The analysis covered 1422 articles,reflecting a substantial rise in publications from 77 articles between 1993 and 2002 to 960 articles between 2013 and 2022.The Western Pacific region led in pub-lication numbers with 622 articles(43.7%),followed by Europe(466 articles;32.8%),Americas(250 articles;17.6%),Eastern Mediterranean(62 articles;4.4%),and Southeast Asia(22 articles;1.5%),with Africa showing a research void.Regrettably,only 29.6%(421 articles)were incorporated into guidelines.The low rate of inclusion of research results in guidelines and the uneven distribution of research fields are particularly prominent.From 1993 to 2002,there were 77 articles,among which 51(66.2%)were included in the guidelines;from 2003 to 2012,there were 385 articles,with 202(52.5%)included;from 2013 to 2022,there were 960 articles,and only 168(17.5%)were included,showing a decreasing trend in the inclusion rate year by year.Regarding geographical distribution,1167 articles were from the East-ern Hemisphere,with 326(27.9%)included;255 were from the Western Hemisphere,and 95(37.3%)were included.Regionally,179 articles(42.5%)from Europe were included,140(33.3%)from the West-ern Pacific,95(22.6%)from the Americas,6(1.4%)from the Eastern Mediterranean,and 1(0.2%)from Southeast Asia.China,the United States,and Germany were the top publishing countries,with consis-tent growth in countries like China,South Korea,Spain,Brazil,Turkey,and Iran.Noteworthy researchers such as Cesar Fernandez-de-las-Penas,Zhi-shun LIU,Jing-wen YANG,Cun-zhi LIU,Li-xing LAO,Stefan N Willich,and Benno Brinkhaus have collaborated on research in areas such as pain management,cognitive impairments,insomnia,digestive system diseases,and urinary system diseases.There has been a partic-ular increase in research focus on neck pain and myofascial trigger points.
基金Hubei Provincial Natural Science Foundation Innovation and Development Joint Fund Project(Project No.:2025AFD278)Three Gorges University Scientific Fund Project(Project No.:2022kj008)Three Gorges University Special Scientific Fund Project(Project No.:2023kjzx001)。
文摘Objective:This paper conducts a bibliometric analysis of the literature on neck pain research from 2000 to 2025,aiming to comprehensively and systematically understand the research landscape,hotspots,and frontier trends in this field,providing a reference for future research directions.Methods:Data were sourced from the Web of Science Core Collection,with the search term TI=“neck pain,”covering the time span from 2000 to 2025,resulting in 2746 articles.Software such as CiteSpace V6.3.R1 and VOSviewer 1.6.20 was used to analyze publication volume,countries,authors,institutions,keywords,and co-citation networks.Results:The number of publications in neck pain research has been increasing year by year,indicating a rising level of research activity.Authors like Falla,D,Jull,G,and institutions such as Univ Queensland and Univ Toronto have significant influence in this field.Co-occurrence analysis of keywords shows that“neck pain,”“low back pain,”and“disability index”are high-frequency keywords,reflecting research hotspots such as the characteristics and treatment of neck pain and its interrelation with pain in other regions.Timeline analysis and keyword emergence analysis reveal the frontiers and development trends in this field,such as the growing attention on emerging therapeutic methods like“exercise therapy”and“dry needling,”while keywords like“intensity,”“individuals,”and“quality”indicate an increasing emphasis on personalization,precision,and quality control in the treatment process.Conclusion:The field of neck pain research is continuously expanding and deepening.Future research should further investigate the pathogenesis of neck pain,its associations with other conditions,the refinement of assessment methods,and the development of innovative rehabilitation strategies.Emphasis should also be placed on interdisciplinary collaboration to provide more robust theoretical foundations and practical guidance for the clinical treatment and rehabilitation management of neck pain.
文摘With an optimised hall layout,progressive design collaborations,inspiring trends and AIdriven innovations,Heimtextil 2026 reacts to the current market situation–and offers the industry a reliable constant in challenging times.Under the motto‘Lead the Change’,the leading trade fair for home and contract textiles and textile design shows how challenges can be turned into opportunities.From 13 to 16 January,more than 3,100 exhibitors from 65 countries will provide a comprehensive market overview with new collections and textile solutions.As a knowledge hub,Heimtextil delivers new strategies and concrete solutions for future business success.
文摘Background:Over the past 15 years,research has emphasized the crucial role of the gut microbiota in metabolism and its potential association with osteoporosis.Given the increasing interest in this area,a bibliometric analysis is essential to comprehensively understand the field.Methods:Literature published between 2009 and 2023 was retrieved from the Web of Science.CiteSpace,a tool for visual analysis,was employed to examine various aspects of the research,including the annual number of publications,contributing institutions,journals,authors,keywords,clusters,hotspots,and emerging frontiers.Results:The analysis included 1,075 articles from 80 countries,283 institutions,and 155 authors,reflecting the rapid growth of research in this field.PEOPLES R CHINA emerged as the most productive country,while the University of California System was the most active institution.Parameswaran,Narayanan had the highest number of publications,and LI JY and OHLSSON C were the most cited authors.Key keywords such as“gut microbiota,”“bone loss,”“bone mineral density,”“inflammation,”and“health”were identified,and keywords with strong citation bursts like“in vitro,”“inflammatory bowel disease,”and“bone mineral density”indicated emerging trends.Conclusion:This bibliometric analysis successfully identified research trends and hotspots,including the fecal microbiome,musculoskeletal studies,and postmenopausal women.Continued research in these areas will enhance our understanding of osteoporosis and may lead to the development of new treatments.The findings offer valuable insights for scholars aiming to conduct in-depth research in this field.
