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Low-density lipoprotein receptor–related protein 1 mediatesα-synuclein transmission from the striatum to the substantia nigra in animal models of Parkinson's disease
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作者 Hanjiang Luo Caixia Peng +5 位作者 Chengli Wu Chengwei Liu Qinghua Li Shun Yu Jia Liu Min Chen 《Neural Regeneration Research》 2026年第4期1595-1606,共12页
α-Synuclein accumulation and transmission are vital to the pathogenesis of Parkinson's disease,although the mechanisms underlying misfoldedα-synuclein accumulation and propagation have not been conclusively dete... α-Synuclein accumulation and transmission are vital to the pathogenesis of Parkinson's disease,although the mechanisms underlying misfoldedα-synuclein accumulation and propagation have not been conclusively determined.The expression of low-density lipoprotein receptor–related protein 1,which is abundantly expressed in neurons and considered to be a multifunctional endocytic receptor,is elevated in the neurons of patients with Parkinson's disease.However,whether there is a direct link between low-density lipoprotein receptor–related protein 1 andα-synuclein aggregation and propagation in Parkinson's disease remains unclear.Here,we established animal models of Parkinson's disease by inoculating monkeys and mice withα-synuclein pre-formed fibrils and observed elevated low-density lipoprotein receptor–related protein 1 levels in the striatum and substantia nigra,accompanied by dopaminergic neuron loss and increasedα-synuclein levels.However,low-density lipoprotein receptor–related protein 1 knockdown efficiently rescued dopaminergic neurodegeneration and inhibited the increase inα-synuclein levels in the nigrostriatal system.In HEK293A cells overexpressingα-synuclein fragments,low-density lipoprotein receptor–related protein 1 levels were upregulated only when the N-terminus ofα-synuclein was present,whereas anα-synuclein fragment lacking the N-terminus did not lead to low-density lipoprotein receptor–related protein 1 upregulation.Furthermore,the N-terminus ofα-synuclein was found to be rich in lysine residues,and blocking lysine residues in PC12 cells treated withα-synuclein pre-formed fibrils effectively reduced the elevated low-density lipoprotein receptor–related protein 1 andα-synuclein levels.These findings indicate that low-density lipoprotein receptor–related protein 1 regulates pathological transmission ofα-synuclein from the striatum to the substantia nigra in the nigrostriatal system via lysine residues in theα-synuclein N-terminus. 展开更多
关键词 Α-SYNUCLEIN dopaminergic neurodegeneration INTERNALIZATION low-density lipoprotein receptor-related protein 1 lysine pre-formed fibril movement disorder nigrostriatal system Parkinson's disease transmission
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Cost effective technologies for long range microwave wireless power transmission
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作者 CHOI Joon-Min KIM Dae-Kwan +3 位作者 PARK Durk-Jong YI Sang-Hwa KIM Dong-Min KO Dae-Ho 《中国空间科学技术(中英文)》 北大核心 2026年第1期122-134,共13页
Space-Based Solar Power(SBSP) presents a promising solution for achieving carbon neutrality and Renewable Electricity 100%(RE100) goals by offering a stable and continuous energy supply. However, its commercialization... Space-Based Solar Power(SBSP) presents a promising solution for achieving carbon neutrality and Renewable Electricity 100%(RE100) goals by offering a stable and continuous energy supply. However, its commercialization faces significant obstacles due to the technical challenges of long-distance microwave Wireless Power Transmission(WPT) from geostationary orbit. Even ground-based kilometer-scale WPT experiments remain difficult because of limited testing infrastructure, high costs, and strict electromagnetic wave regulations. Since the 1975 NASA-Raytheon experiment, which successfully recovered 30 kW of power over 1.55 km, there has been little progress in extending the transmission distance or increasing the retrieved power. This study proposes a cost-effective methodology for conducting long-range WPT experiments in constrained environments by utilizing existing infrastructure. A deep space antenna operating at 2.08 GHz with an output power of 2.3 kW and a gain of 55.3 dBi was used as the transmitter. Two test configurations were implemented: a 1.81 km ground-to-air test using an aerostat to elevate the receiver and a 1.82 km ground-to-ground test using a ladder truck positioned on a plateau. The rectenna consists of a lightweight 3×3 patch antenna array(0.9 m × 0.9 m), accompanied by a steering device and LED indicators to verify power reception. The aerostat-based test achieved a power density of 154.6 mW/m2, which corresponds to approximately 6.2% of the theoretical maximum. The performance gap is primarily attributed to near-field interference, detuning of the patch antenna, rectifier mismatch, and alignment issues. These limitations are expected to be mitigated through improved patch antenna fabrication, a transition from GaN to GaAs rectifiers optimized for lower input power, and the implementation of an automated alignment system. With these enhancements, the recovered power is expected to improve by approximately four to five times. The results demonstrate a practical and scalable framework for long-range WPT experiments under constrained conditions and provide key insights for advancing SBSP technology. 展开更多
关键词 wireless power transmission space-based solar power deep space antenna DSP KDSA KARI RECTENNA AEROSTAT
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S-scheme unidirectional transmission of CdS-CuO heterojunction benefits for superior photocatalytic hydrogen evolution efficiency
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作者 ZHAO Haiting YAN Zheng +2 位作者 LIU Yang JIANG Longde LUAN Jingde 《燃料化学学报(中英文)》 北大核心 2026年第1期1-14,共14页
The efficiency and stability of catalysts for photocatalytic hydrogen evolution(PHE)are largely governed by the charge transfer behaviors across the heterojunction interfaces.In this study,CuO,a typical semiconductor ... The efficiency and stability of catalysts for photocatalytic hydrogen evolution(PHE)are largely governed by the charge transfer behaviors across the heterojunction interfaces.In this study,CuO,a typical semiconductor featuring a broad spectral absorption range,is successfully employed as the electron acceptor to combine with CdS for constructing a S-scheme heterojunction.The optimized photocatalyst(CdSCuO2∶1)delivers an exceptional hydrogen evolution rate of 18.89 mmol/(g·h),4.15-fold higher compared with bare CdS.X-ray photoelectron spectroscopy(XPS)and ultraviolet-visible diffuse reflection absorption spectroscopy(UV-vis DRS)confirmed the S-scheme band structure of the composites.Moreover,the surface photovoltage(SPV)and electron paramagnetic resonance(EPR)indicated that the photogenerated electrons and photogenerated holes of CdS-CuO2∶1 were respectively transferred to the conduction band(CB)of CdS with a higher reduction potential and the valence band(VB)of CuO with a higher oxidation potential under illumination,as expected for the S-scheme mechanism.Density-functional-theory calculations of the electron density difference(EDD)disclose an interfacial electric field oriented from CdS to CuO.This built-in field suppresses charge recombination and accelerates carrier migration,rationalizing the markedly enhanced PHE activity.This study offers a novel strategy for designing S-scheme heterojunctions with high light harvesting and charge utilization toward sustainable solar-tohydrogen conversion. 展开更多
关键词 photocatalytic hydrogen evolution CdS-CuO S-scheme heterojunction electron directional transmission interfacial electric field DFT calculation
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Reconstruction of the"Reader Centered"Paradigm in the Teaching of High School English Literary Text Reading from the Perspective of Reception Aesthetics
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作者 Zhuohao Fei 《Research on Educational Theory》 2026年第1期1-6,共6页
This study focuses on reconstructing the"reader-centered"paradigm in the teaching of high school English literary text reading,supported by Reception Aesthetics as its theoretical foundation.High school Engl... This study focuses on reconstructing the"reader-centered"paradigm in the teaching of high school English literary text reading,supported by Reception Aesthetics as its theoretical foundation.High school English literary text reading plays a significant role in cultivating students'language proficiency,cultural awareness,and aesthetic literacy.However,the current teaching practice in this area remains dominated by the traditional"teacher-centered"approach,which restricts students'active participation and the realization of the pluralistic value of literary texts.By integrating core concepts of Reception Aesthetics-such as"horizon of expectations,""structure of appeal,"and"interpretive community"-this research addresses the gap in existing studies,which have largely focused on the application of Reception Aesthetics in Chinese language teaching or college English instruction.Using literature research and classroom practice analysis,the study reconstructs the"reader-centered"paradigm across three dimensions:teaching objectives,teaching process,and evaluation methods.It also identifies practical challenges,including uneven student participation,time constraints,and difficulties in the teacher's role adaptation,and proposes corresponding optimization strategies.Practical results demonstrate that this paradigm effectively enhances students'reading engagement,text interpretation skills,and critical thinking.Future research may further expand text types and integrate information technology to continuously improve teaching effectiveness. 展开更多
关键词 reception Aesthetics Reader Centered English teaching
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Nonreciprocal transmission in a dual WGM resonators-waveguide system via synergistic Sagnac and scattering effects
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作者 Gang Li Yong Yong Gong +3 位作者 De-Xiu Qiu Ying Qiao Zhang Chengshou An Xing Ri Jin 《Communications in Theoretical Physics》 2026年第2期15-24,共10页
We propose a scheme to achieve nonreciprocal single-photon transmission in a system consisting of a spinning whispering-gallery-mode resonator and a stationary resonator containing a scatterer,both coupled to a one-di... We propose a scheme to achieve nonreciprocal single-photon transmission in a system consisting of a spinning whispering-gallery-mode resonator and a stationary resonator containing a scatterer,both coupled to a one-dimensional waveguide.By tuning the Sagnac-Fizeau shift induced by the spinning resonator,high-contrast nonreciprocal transmission in both forward and backward directions can be realized.Furthermore,we investigate the influences of system parameters including waveguide-resonator coupling strength,inter-mode coupling strengths within two resonators,and inter-cavity coupling strength on nonreciprocal transmissions.The results indicate that the synergistic regulation of these parameters can adjust the position of the nonreciprocal transmission peak and achieve high-contrast nonreciprocal transmission. 展开更多
关键词 nonreciprocal transmission WGM resonator SCATTERER Sagnac-Fizeau shift
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Enhanced atomic localization and precision control in a four-level atomic medium via transmission spectrum
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作者 Muhammad Idrees Fatima Ghulam Kakepoto Zareen A Khan 《Communications in Theoretical Physics》 2026年第1期51-60,共10页
In this article,we introduce a new theoretical approach to improve the accuracy of twodimensional(2D)atomic localization within a tripod-type,four-level atomic system by analyzing its transmission spectrum.In this met... In this article,we introduce a new theoretical approach to improve the accuracy of twodimensional(2D)atomic localization within a tripod-type,four-level atomic system by analyzing its transmission spectrum.In this method,the atom interacts with two orthogonal standing-wave fields and a weak probe field.By examining how the weak probe field passes through the system,we can determine the atom position.Our analysis reveals the presence of both double and sharply defined single localized peaks in the transmission spectrum,which correspond to specific positions of the atom.Importantly,we achieve ultra-high-resolution atomic localization with accuracy confined to a region smaller thanλ/32×λ/32.This level of precision is a significant improvement compared to earlier methods,which had lower localization accuracy.The increased precision is due to the complex interaction between the atom and the carefully controlled standing-wave and probe fields,which allows for precise control over the atom's position.The implications of this work are significant,especially for applications like nano-lithography,where precise atomic placement is essential,and for laser cooling technologies,where better atomic localization could lead to more effective cooling processes and improved manipulation of atomic states. 展开更多
关键词 atomic localization transmission spectrum standing-wave fields ultra-high resolution nano-lithography
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Review of Deep Learning-Based Intelligent Inspection Research for Transmission Lines
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作者 Jingjing Liu Chuanyang Liu 《Computers, Materials & Continua》 2026年第5期155-198,共44页
Intelligent inspection of transmission lines enables efficient automated fault detection by integrating artificial intelligence,robotics,and other related technologies.It plays a key role in ensuring power grid safety... Intelligent inspection of transmission lines enables efficient automated fault detection by integrating artificial intelligence,robotics,and other related technologies.It plays a key role in ensuring power grid safety,reducing operation and maintenance costs,driving the digital transformation of the power industry,and facilitating the achievement of the dual-carbon goals.This review focuses on vision-based power line inspection,with deep learning as the core perspective to systematically analyze the latest research advancements in this field.Firstly,at the technical foundation level,it elaborates on deep learning algorithms for intelligent transmission line inspection based on image perception,covering object detection algorithms,semantic segmentation algorithms,and other relevant methodologies.Secondly,in application practice,it summarizes deep learning-based intelligent inspection applications across six dimensions—including detection of power insulators and their defects,transmission tower detection,power line feature extraction,metal fitting and defect detection,thermal fault diagnosis of power components,and safety hazard detection in power scenarios,and further lists relevant public datasets.Finally,in response to current challenges,it identifies five key future research directions,such as the deep integration of multiple learning paradigms,multi-modal data fusion,collaborative application of large and small models,cloud-edge-end collaborative integration,and multi-agent cluster control.This paper reviews and analyzes numerous deep learning-based intelligent detectionmethods for aerial images,comprehensively explores the application of deep learning in Unmanned Aerial Vehicle(UAV)inspection scenarios,and thus provides valuable theoretical and practical references for scholars engaged in smart grid automated inspection research. 展开更多
关键词 Intelligent inspection transmission lines deep learning defect detection
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Transmission Characteristics of Biological Pollutant on Cold Surface Through Surface Contact During Cold Storage
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作者 Zhiqiang Wang Lixin Chen +3 位作者 Saiwei Ge Wei Xiao Zhuohao Xuan Pengcheng Zhang 《Journal of Harbin Institute of Technology(New Series)》 2026年第1期20-32,共13页
The cold chain environment is an important route for the long⁃distance transmission of pathogenic micro⁃organisms.In this study,we explored the mechanisms of secondary propagation through surface contact on cold surfa... The cold chain environment is an important route for the long⁃distance transmission of pathogenic micro⁃organisms.In this study,we explored the mechanisms of secondary propagation through surface contact on cold surfaces.A quantitative statistical experimental method was adopted to study the surface⁃contact transmission of micro⁃organisms,wherein the transfer rate of surface contact was the dependent variable and Escherichia coli was used as the indicator bacterium.The effects of contact pressure(0.44,0.86,1.55,2.25,and 2.94 N/cm^(2)),contact time(0,15,30,45,and 60 s),contact angle(15°and 25°),and surface materials(rubber and cotton gloves)were measured at two storage temperatures:cold storage(5℃)and freezing(-18℃).The results showed that as temperature decreases,the transfer of micro⁃organisms through surface contact becomes less probable.The contact time did not significantly influence the transfer rate of micro⁃organisms when items were handled at cold⁃storage temperatures.Based on these results,we recommend placing items as flat as possible to minimize the tilt angle when handling them at cold⁃storage temperatures.Additionally,if the tilt angle cannot be avoided,rubber gloves should be used when handling items stored at large tilt angles,whereas cotton gloves may be used for items placed at smaller angles. 展开更多
关键词 cold chain biological pollutant surface contact transfer rate transmission characteristics
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Construction of MMC-CLCC Hybrid DC Transmission System and Its Power Flow Reversal Control Strategy
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作者 Yechun Xin Xinyuan Zhao +3 位作者 Dong Ding Shuyu Chen Chuanjie Wang Tuo Wang 《Energy Engineering》 2026年第1期460-474,共15页
To enhance power flow regulation in scenarios involving large-scale renewable energy transmission via high-voltage direct current(HVDC)links and multi-infeed DC systems in load-center regions,this paper proposes a hyb... To enhance power flow regulation in scenarios involving large-scale renewable energy transmission via high-voltage direct current(HVDC)links and multi-infeed DC systems in load-center regions,this paper proposes a hybrid modular multilevel converter–capacitor-commutated line-commutated converter(MMC-CLCC)HVDC transmission system and its corresponding control strategy.First,the system topology is constructed,and a submodule configuration method for the MMC—combining full-bridge submodules(FBSMs)and half-bridge submodules(HBSMs)—is proposed to enable direct power flow reversal.Second,a hierarchical control strategy is introduced,includingMMCvoltage control,CLCC current control,and a coordinationmechanism,along with the derivation of the hybrid system’s power flow reversal characteristics.Third,leveraging the CLCC’s fast current regulation and theMMC’s negative voltage control capability,a coordinated power flow reversal control strategy is developed.Finally,an 800 kV MMC-CLCC hybrid HVDC system is modeled in PSCAD/EMTDC to validate the power flow reversal performance under a high proportion of full-bridge submodule configuration.Results demonstrate that the proposed control strategy enables rapid(1-s transition)and smooth switching of bidirectional power flow without modifying the structure of primary equipment:the transient fluctuation ofDC voltage from the rated value(UdcN)to themaximumreverse voltage(-kUdcN)is less than 5%;the DC current strictly follows the preset characteristic curve with a deviation of≤3%;the active power reverses continuously,and the system maintains stable operation throughout the reversal process. 展开更多
关键词 Hybrid HVDC transmission modular multilevel converter(MMC) controllable line commutated converter(CLCC) online power flow reversal full-bridge and half-bridge submodules new energy through dc transmission system
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Establishing an induced infertile chicken line for efficient germline transmission of exogenous PGCs
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作者 Haimei Qin Xiaoxuan Jia +7 位作者 Zhenwen Huang Yifei Zhi Na Ji Meiyu Lan Lang Zhang Xingting Liu Huiyan Xu Yangqing Lu 《Journal of Integrative Agriculture》 2026年第1期227-234,共8页
Primordial germ cells(PGCs)are the stem-cell population of adult animal gametes,which develop into sperm or eggs.It can be propagated in vitro and injected into the host chicken for genome editing to obtain germline c... Primordial germ cells(PGCs)are the stem-cell population of adult animal gametes,which develop into sperm or eggs.It can be propagated in vitro and injected into the host chicken for genome editing to obtain germline chimeric chicken.However,it has the limitation that the host embryo contains endogenous PGCs,which raises complications,resultantly donor PGCs fail to compete,and transmission efficiency reduced.Therefore,to increase the transmission efficiency,we generated a novel sterile chicken with the inducible elimination of endogenous PGCs in the host.This is the first study that applied the herpes simplex virus thymidine kinase(HSV-TK)cell ablation system in avian.CRISPR/Cas9-mediated homology-directed repair was performed to localize the HSV-TK suicide gene to the last exon of the deleted in azoospermialike(DAZL)gene,and ganciclovir(GCV)was added to induce the apoptosis in the germ cells of the host embryo.The sterilized host embryo introduced genome-edited PGCs to produce chimeric chicken carrying exogenous germ cells only.It was observed that the germline transmission efficiency was 100%achieved,and the obtained chicks were purely from donor breeds.The technologies established in the current study have important applications in germplasm conservation and gene editing in chicken. 展开更多
关键词 chicken embryos germline transmission efficiency herpes simplex virus thymidine kinase primordial germ cells
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Enhanced sparse RCNN for transmission line bolt defect detection via text-to-image data augmentation and quality filtering
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作者 Chen Zhenyu Yan Huaguang +2 位作者 Du Jianguang Xue Meng Zhao Shuai 《High Technology Letters》 2026年第1期11-20,共10页
To address the issue of inconsistent image quality and data scarcity in bolt defect detection for transmission lines,this paper proposes an improved sparse region-based convolutional neural network(RCNN) based detecti... To address the issue of inconsistent image quality and data scarcity in bolt defect detection for transmission lines,this paper proposes an improved sparse region-based convolutional neural network(RCNN) based detection framework integrating image quality evaluation and text-to-image data augmentation.First,a HyperNetwork-based image quality assessment module is introduced to filter low-quality inspection images in terms of clarity and structural integrity,resulting in a high-quality training dataset.Second,a text-to-image diffusion model is utilized for sample augmentation.By designing text prompts that describe various bolt defect types under diverse lighting and viewing conditions,the model automatically generates realistic synthetic samples.The generated images are further filtered using a combination of quality and perceptual similarity metrics to ensure consistency with the real data distribution.Building upon the sparse RCNN baseline,a dynamic label assignment mechanism and a random decision path detection head are incorporated to enhance bounding box matching and prediction accuracy.Experimental results demonstrate that the proposed method significantly improves detection accuracy(mAP@0.5) over the original sparse RCNN while maintaining low computational cost,enabling more efficient and intelligent inspection of transmission line components. 展开更多
关键词 sparse region-based convolutional neural network HyperNetwork image quality assessment text-to-image generation data augmentation bolt defect detection transmission line inspection
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Modeling of a DVB-S2 Transmission Chain with Optimization of Adjustment Parameters for a Good Quality of the Reception Signal
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作者 Patrick Dany Bavoua Kenfack Alphonse Binele Abana +1 位作者 Emmanuel Tonye Salim Adjiali Boukar 《International Journal of Communications, Network and System Sciences》 2023年第1期1-20,共20页
Digital television is part of our daily lives. We took an interest in the DVB-S2 standard in particular, because it is the one that governs the transmission by satellite of multimedia content from television programs.... Digital television is part of our daily lives. We took an interest in the DVB-S2 standard in particular, because it is the one that governs the transmission by satellite of multimedia content from television programs. With ever-changing user needs, there are new challenges that the DVB-S2 standard is no longer able to meet due to errors caused by weather and hardware limitations. The main purpose of a satellite TV transmission is to obtain a video signal in reception of the best possible quality and at a high bit rate. It is therefore important to determine all the factors which could intervene in the process of transmission and which have a negative impact on the yield at the reception of the signal. We therefore designed and simulated the DVB-S and DVB-S2 transmission chains with QPSK modulation (and an FEC coding rate of 1/2), on MATLAB software (Simulink), and with an AWGN channel for the sake of comparison performance between these two chains. Then we carried out the design of the DVB-S2 transmission chain with an RF (Radio Frequency) satellite channel, by materializing all the elements which intervene in the downlink to evaluate the performance of this chain according to the factors which influence and/or degrade the signal quality between transmission and reception at the receiving earth station. The main results obtained relate to the DVB-S2 transmission chain and were interpreted using the visualization of the error rate blocks: With an AWGN channel, increasing the signal-to-noise ratio decreases the rate of erroneous packets and therefore improves the quality of the received signal. With an RF satellite channel on the downlink: increasing the transmit power improves the receive performance, this is useful for correcting most RF imperfections;having larger parabolic antennas is an advantage because they have greater gains;this makes it possible to minimize the rate of erroneous packets. These simulations allowed us to determine the precise and numerical impact of RF degradations on the performance of the downlink DVB-S2 transmission chain. 展开更多
关键词 DVB-S2 MODULATION AWGN RF Imperfection TV transmission
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Zika virus transmission in Aedes aegypti:A systematic study on the ability of mosquitoes to transmit the virus horizontally and vertically 被引量:1
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作者 Xugang Wang Chaonan Qian +13 位作者 Chenxi Zhang Siyun Hu Muhammad Asad Chengjie Yang Bingrui Liao Xiaotong Guo Chen Zhang Quanzhi Li Xinyao Li Qiuying Huang Youhui Si Bibo Zhu Shengbo Cao Jing Ye 《Virologica Sinica》 2025年第2期192-205,共14页
Zika virus(ZIKV)is a mosquito-borne virus belonging to the genus Orthoflavivirus,and the family Flaviviridae.It commonly presents with febrile-like symptoms,neurological issues,and pregnancy complications in humans.Cu... Zika virus(ZIKV)is a mosquito-borne virus belonging to the genus Orthoflavivirus,and the family Flaviviridae.It commonly presents with febrile-like symptoms,neurological issues,and pregnancy complications in humans.Currently,there is no commercial vaccine or specific treatment available to prevent ZIKV infection.Therefore,controlling the epidemic's spread relies on preventing mosquitoes from transmitting the virus.Although various studies have explored the transmission of ZIKV between mosquitoes and vertebrate hosts,comprehensive research on potential mosquito-to-mosquito transmission of ZIKV remains limited.In this study,we conducted systematic laboratory investigations to assess the ability of ZIKV to spread among mosquitoes,and to evaluate the impact of ZIKV infection on mosquito development.Our findings revealed that ZIKV can be transmitted between Aedes aegypti mosquitoes both vertically and horizontally,through oviposition and contact between mosquitoes of the same or opposite sex.Additionally,we observed that ZIKV infection resulted in a reduction in the number of mosquito eggs but an increase in their size.The widespread distribution of ZIKV in infected mosquitoes and the altered levels of hormone related genes following viral infection were noted,which may contribute to viral transmission among mosquitoes and affect mosquito development.This research provides systematic experimental evidence of ZIKV transmission among mosquitoes,which is crucial for developing novel strategies to disrupt the spread of orthoflaviviruses and other mosquitoborne pathogens. 展开更多
关键词 Zika virus(ZIKV) Aedes aegypti Horizontal transmission Vertical transmission
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GFRF R-CNN:Object Detection Algorithm for Transmission Lines
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作者 Xunguang Yan Wenrui Wang +3 位作者 Fanglin Lu Hongyong Fan Bo Wu Jianfeng Yu 《Computers, Materials & Continua》 SCIE EI 2025年第1期1439-1458,共20页
To maintain the reliability of power systems,routine inspections using drones equipped with advanced object detection algorithms are essential for preempting power-related issues.The increasing resolution of drone-cap... To maintain the reliability of power systems,routine inspections using drones equipped with advanced object detection algorithms are essential for preempting power-related issues.The increasing resolution of drone-captured images has posed a challenge for traditional target detection methods,especially in identifying small objects in high-resolution images.This study presents an enhanced object detection algorithm based on the Faster Regionbased Convolutional Neural Network(Faster R-CNN)framework,specifically tailored for detecting small-scale electrical components like insulators,shock hammers,and screws in transmission line.The algorithm features an improved backbone network for Faster R-CNN,which significantly boosts the feature extraction network’s ability to detect fine details.The Region Proposal Network is optimized using a method of guided feature refinement(GFR),which achieves a balance between accuracy and speed.The incorporation of Generalized Intersection over Union(GIOU)and Region of Interest(ROI)Align further refines themodel’s accuracy.Experimental results demonstrate a notable improvement in mean Average Precision,reaching 89.3%,an 11.1%increase compared to the standard Faster R-CNN.This highlights the effectiveness of the proposed algorithm in identifying electrical components in high-resolution aerial images. 展开更多
关键词 Faster R-CNN transmission line object detection GIOU GFR
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An Interpretable Few-Shot Framework for Fault Diagnosis of Train Transmission Systems with Noisy Labels 被引量:1
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作者 Haiquan Qiu Biao Wang +4 位作者 Yong Qin Ao Ding Zhixin He Jing Liu Xin Huang 《Journal of Dynamics, Monitoring and Diagnostics》 2025年第1期65-75,共11页
Intelligent fault diagnosis technology plays an indispensable role in ensuring the safety,stability,and efficiency of railway operations.However,existing studies have the following limitations.1)They are typical black-... Intelligent fault diagnosis technology plays an indispensable role in ensuring the safety,stability,and efficiency of railway operations.However,existing studies have the following limitations.1)They are typical black-box models that lacks interpretability as well as they fuse features by simply stacking them,overlooking the discrepancies in the importance of different features,which reduces the credibility and diagnosis accuracy of the models.2)They ignore the effects of potentially mistaken labels in the training datasets disrupting the ability of the models to learn the true data distribution,which degrades the generalization performance of intelligent diagnosis models,especially when the training samples are limited.To address the above items,an interpretable few-shot framework for fault diagnosis with noisy labels is proposed for train transmission systems.In the proposed framework,a feature extractor is constructed by stacked frequency band focus modules,which can capture signal features in different frequency bands and further adaptively concentrate on the features corresponding to the potential fault characteristic frequency.Then,according to prototypical network,a novel metric-based classifier is developed that is tolerant to mislabeled support samples in the case of limited samples.Besides,a new loss function is designed to decrease the impact of label mistakes in query datasets.Finally,fault simulation experiments of subway train transmission systems are designed and conducted,and the effectiveness as well as superiority of the proposed method are proved by ablation experiments and comparison with the existing methods. 展开更多
关键词 few-shot learning intelligent fault diagnosis INTERPRETABILITY noisy labels train transmission systems
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Combining machine learning algorithms with traditional methods for resolving the atomic-scale dynamic structure of monolayer MoS_(2) in high-resolution transmission electron microscopy 被引量:1
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作者 Yu Meng Shuya Wang +5 位作者 Xibiao Ren Han Xue Xuejun Yue Chuanhong Jin Shanggang Lin Fang Lin 《Chinese Physics B》 2025年第1期162-170,共9页
High-resolution transmission electron microscopy(HRTEM)promises rapid atomic-scale dynamic structure imaging.Yet,the precision limitations of aberration parameters and the challenge of eliminating aberrations in Cs-co... High-resolution transmission electron microscopy(HRTEM)promises rapid atomic-scale dynamic structure imaging.Yet,the precision limitations of aberration parameters and the challenge of eliminating aberrations in Cs-corrected transmission electron microscopy constrain resolution.A machine learning algorithm is developed to determine the aberration parameters with higher precision from small,lattice-periodic crystal images.The proposed algorithm is then validated with simulated HRTEM images of graphene and applied to the experimental images of a molybdenum disulfide(MoS_(2))monolayer with 25 variables(14 aberrations)resolved in wide ranges.Using these measured parameters,the phases of the exit-wave functions are reconstructed for each image in a focal series of MoS_(2)monolayers.The images were acquired due to the unexpected movement of the specimen holder.Four-dimensional data extraction reveals time-varying atomic structures and ripple.In particular,the atomic evolution of the sulfur-vacancy point and line defects,as well as the edge structure near the amorphous,is visualized as the resolution has been improved from about 1.75?to 0.9 A.This method can help salvage important transmission electron microscope images and is beneficial for the images obtained from electron microscopes with average stability. 展开更多
关键词 aberration measurement high-resolution transmission electron microscopy feature-extraction networks exit-wave reconstruction monolayer MoS_(2)
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Activities of nicotinic acetylcholine receptors modulate neurotransmission and synaptic architecture 被引量:1
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作者 Akira Oda Hidekazu Tanaka 《Neural Regeneration Research》 SCIE CAS CSCD 2014年第24期2128-2131,共4页
The cholinergic system is involved in a broad spectrum of brain function, and its failure has been implicated in Alzheimer's disease. Acetylcholine transduces signals through muscarinic and nicotinic acetylcholine re... The cholinergic system is involved in a broad spectrum of brain function, and its failure has been implicated in Alzheimer's disease. Acetylcholine transduces signals through muscarinic and nicotinic acetylcholine receptors, both of which influence synaptic plasticity and cognition. However, the mechanisms that relate the rapid gating of nicotinic acetylcholine receptors to persistent changes in brain function have remained elusive. Recent evidence indicates that nicotinic acetylcholine receptors activities affect synaptic morphology and density, which result in persistent rearrangements of neural connectivity. Further investigations of the relationships between nicotinic acetylcholine receptors and rearrangements of neural circuitry in the central nervous system may help understand the pathogenesis of Alzheimer's disease. 展开更多
关键词 cholinergic system nicotinic acetylcholine receptors (nAChRs) Alzheimer's disease (AD) synaptic transmission synaptic plasticity synaptic morphology dendritic spine remodeling COGNITION
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Microwave power transmission technologies for space solar power station
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作者 YANG Bo SHINOHARA Naoki 《中国空间科学技术(中英文)》 北大核心 2025年第2期1-14,共14页
The microwave wireless power transmission technologies for space solar power station are a crucial field in the international space sector,where various countries are competing in its development.This paper surveys th... The microwave wireless power transmission technologies for space solar power station are a crucial field in the international space sector,where various countries are competing in its development.This paper surveys the research experiments and development efforts related to space solar power stations and microwave wireless power transmission technologies worldwide.The objective is to assess the progress and current state of this technological foundation,determine the necessary focus for developing high-power microwave wireless power transmission technology,and provide clarity on the direction of future technology development in these areas.Finally,a distributed space solar power station plan that is immediately feasible is proposed. 展开更多
关键词 microwave power transmission space solar power station wireless power transfer microwave transmitter phased array rectenna array
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Vibration Transmission Characteristics of Shoe Sole Based on Mechanical Mobility and Vibration Transmissibility
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作者 WU Xuyang LIU Xiaoying +2 位作者 HAO Yanhua LIU Changhuang HUANG Xianwei 《Journal of Shanghai Jiaotong university(Science)》 2025年第1期175-186,共12页
It is particularly important to explore the response and transmission characteristics of shoe sole when exposed to foot-transmitted vibration(FTV)in daily life.In this study,based on mechanical mobility and vibration ... It is particularly important to explore the response and transmission characteristics of shoe sole when exposed to foot-transmitted vibration(FTV)in daily life.In this study,based on mechanical mobility and vibration transmissibility,the vibration response and transmission characteristics of ordinary sole and multi-cellular structure sole under three excitation modes were analyzed with finite element analysis.The analysis results of the ordinary sole are as follows:The distribution and transmission of vibration energy of ordinary sole are more related to the excitation position and mode-shape;the phalange region is more violent in vibration response to vibration and transmission of vibration.In addition,the analysis results of multi-cellular structure soles show that different types of multi-cellular structure soles have different effects on the equivalent mechanical mobility and the equivalent vibration transmissibility,among which Grid type has the greatest influence.So,this study can help prevent foot injury and provide guidance for the optimal design of the sole. 展开更多
关键词 vibration transmission characteristics mechanical mobility vibration transmissibility vibration energy shoe sole
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NYBELT:Leading the world in high-performance flat transmission belts
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《China Textile》 2025年第5期38-38,共1页
With the most advanced and sophisticated technologies and equipment,NYBELT is one of the largest manufacturers of flat transmission belts in the world.Under the Certified Quality,Environment,Occupational Health&Sa... With the most advanced and sophisticated technologies and equipment,NYBELT is one of the largest manufacturers of flat transmission belts in the world.Under the Certified Quality,Environment,Occupational Health&Safety,and Energy Standardized ISO Management System,NYBELT can produce all kinds of flat transmission belts,roller coverings and conveyor belts applicable to textile,printing&packaging,electronics and other industries.Due to the superior quality and the reasonable prices,we have become well known in providing high quality belting products and excellent service to customers all over the world.Our success in the past gives us the confidence to look into the future with great expectations. 展开更多
关键词 flat transmission belts high performance flat transmission belts roller coverings flat transmission beltsroller coverings standardized iso management iso management system conveyor belts advanced technologies
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